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The role of agricultural mechanization technology in the promotion of scientific and technological achievements in agriculture
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作者 Zhiying TANG Xiaoming FU 《International Journal of Technology Management》 2014年第11期13-15,共3页
Agricultural mechanization is to the use advanced and applicable agricultural machinery and equipment in agriculture to improve agricultural production conditions, and continuously improve the production technology an... Agricultural mechanization is to the use advanced and applicable agricultural machinery and equipment in agriculture to improve agricultural production conditions, and continuously improve the production technology and economic, ecological processes of agriculture. The level of agricultural science and technology depends largely on the degree of agricultural mechanization promotion. An agricultural country level depends on the degree of modern agricultural mechanization level of the application, and the era of mechanization in agriculture can not only save a lot of labor, reduce labor intensity, but also improve labor efficiency, and enhance resistance to natural disasters. The importance of agricultural mechanization technology in the scientific and technological achievements in agriculture is visible. 展开更多
关键词 agricultural mechanization technology MARKETING scientific and technological achievements
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Mechanization technology:The key to sugarcane production in China 被引量:18
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作者 Ou Yinggang Malcolm Wegener +4 位作者 Yang Dantong Liu Qingting Zheng Dingke Wang Meimei Liu Haochun 《International Journal of Agricultural and Biological Engineering》 SCIE EI CAS 2013年第1期1-27,共27页
Sugarcane is an important cash crop in southern China now planted on about 1.5 million ha in the main production areas in Guangxi,Zhuang Autonomous Region and Yunnan,Guangdong,and Hainan Provinces.Since the cost of la... Sugarcane is an important cash crop in southern China now planted on about 1.5 million ha in the main production areas in Guangxi,Zhuang Autonomous Region and Yunnan,Guangdong,and Hainan Provinces.Since the cost of labor in China is increasing rapidly and the price of local sugar is uncompetitive with the product from mechanized international producers,China needs to change its sugarcane production methods from manual work to mechanization in order to catch up with international trends in this global industry.Although a lot of effort in China have gone into sugarcane mechanization since the 1960s,the overall level of mechanization in sugarcane production is still only approximately 30%,which is about 20%lower than that achieved in the other main field crops.Almost all of the sugarcane grown in China is still harvested by hand.In order to summarize past experience and promote the mechanization of sugarcane production in China,this paper reviews the whole process of developing mechanization since 1960s and describes the current state of sugarcane mechanization in China.The research currently being undertaken and the main obstacles to be overcome in developing a mechanized sugarcane production system,are described.The design and testing of sugarcane harvesting machinery and its key components has been a significant research area by some Chinese universities,research institutes,and manufacturing companies in these past decades.This paper reviews that research and outlines the main achievements which have been made in this area.Mechanized harvesting systems for sugarcane,and the appropriate harvesting patterns suitable for different growing conditions applying in China,have also been studied.The paper concludes with some comments on the future directions for progress in China’s mechanization of sugarcane production and some policy suggestions to facilitate the industry's transition. 展开更多
关键词 mechanization technology sugarcane production sugarcane harvester sugarcane machinery development pattern
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The study of measuring technology on the dynamic mechanical properties of welded joint with high strainrate 被引量:1
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作者 巩水利 张建勋 +1 位作者 裴怡 于琴 《China Welding》 EI CAS 2000年第1期30-37,共8页
In this paper, to meet the needs of studying work of dynamic mechanical properties of welded joint, the dynamic mechanical properties of welded joint were measured by means of SHPB(Split Hopkinson Pressure Bar).The dy... In this paper, to meet the needs of studying work of dynamic mechanical properties of welded joint, the dynamic mechanical properties of welded joint were measured by means of SHPB(Split Hopkinson Pressure Bar).The dynamic mechanical property's curves of every part of welded joint were obtained. For studying the dynamic behavior of mechanical heterogeneity of welded joint, important data were offered. The method of test creates a new way of studying dynamic mechanical properties of welded joint. 展开更多
关键词 welded joint dynamic mechanical properties measuring technology
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Discussion and Research on Orthopedic Biomechanics Testing Technology
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作者 Jinkui Liang Wanzong Liu +1 位作者 Xiuxiu Wang Yuanyu Li 《Journal of Clinical and Nursing Research》 2020年第6期67-70,共4页
With the continuous development of today's science and technology,orthopedic research has also achieved continuous updates in materials and machinery.In this case,the mechanics testing technology of orthopedics al... With the continuous development of today's science and technology,orthopedic research has also achieved continuous updates in materials and machinery.In this case,the mechanics testing technology of orthopedics also needs to be further updated and developed,so that it can effectively meet the requirement for today's orthopedic mechanical testing.Based on this,this article analyzes several advanced orthopedic mechanics testing techniques.It is hoped that this analysis can provide a reference for the good application and development of orthopedic mechanics testing technology. 展开更多
关键词 ORTHOPEDICS BIOMECHANICS Mechanical testing Testing technology
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Practical Analysis of Mechanical Automation Technology in Automobile Manufacturing
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作者 Miao Zhang 《Journal of Electronic Research and Application》 2023年第5期24-29,共6页
In today’s rapidly developing modern society,automobiles,as an important part of transportation and industrial fields,play a pivotal role.With the improvement of people’s living standards and the increase in traffic... In today’s rapidly developing modern society,automobiles,as an important part of transportation and industrial fields,play a pivotal role.With the improvement of people’s living standards and the increase in traffic demand,the automobile manufacturing industry has been continuously developing and growing globally.However,to cope with increasingly fierce market competition and ever-changing consumer demands,the automobile manufacturing industry is also facing the challenges of improving production efficiency,reducing costs,and improving product quality.In this context,automation technology has gradually become a major trend in the automobile manufacturing industry.As an important support of modern industry,automation technology has shown great application potential in many fields.From industrial production to daily life,automation technology can be seen everywhere.In the field of manufacturing,especially in automobile manufacturing,the application of automation technology is getting more and more attention.Automated production lines,intelligent robots,and automated warehousing systems have all changed the face of automobile manufacturing to varying degrees,bringing companies higher efficiency,more stable quality,and greater competitive advantages.The application trend of this automation technology in various fields not only meets the needs of modern industry for efficient,precise,and sustainable development but also provides new ideas and paths for the future development of the automobile manufacturing industry. 展开更多
关键词 Mechanical automation technology Automobile manufacturing Practical analysis Production efficiency
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Application of Mechanical Oxygen Enrichment Technology in Freshwater Aquaculture
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作者 CAOPeixian 《外文科技期刊数据库(文摘版)自然科学》 2022年第2期033-037,共5页
With the continuous improvement of China's economic level and the continuous improvement of people's quality of life, the freshwater aquaculture industry has also developed rapidly, and the high-yield and high... With the continuous improvement of China's economic level and the continuous improvement of people's quality of life, the freshwater aquaculture industry has also developed rapidly, and the high-yield and high-efficiency aquaculture technology has also been widely used. Under this background, the traditional mechanical oxygenation technology can no longer meet the current aquaculture industry's demand for higher quality. This paper briefly introduces the mechanical oxygenation technology applied in the aquaculture market in Sixian County, Anhui Province, analyzes its market application status and existing problems, and puts forward relevant countermeasures to improve the technical level of oxygenation equipment and aquaculture production, hoping to provide technical support for promoting the sustainable development of freshwater aquaculture in Sixian County. 展开更多
关键词 fresh water AQUACULTURE mechanical oxygenation technology
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Brief Discussion on the Application of Mechanical Automation Technology in Mechanical Manufacturing Industry
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作者 LIUBing 《外文科技期刊数据库(文摘版)工程技术》 2022年第7期044-047,共4页
With the overall improvement and steady development of Chinas science and technology, mechanical automation technology has been widely used in Chinas current mechanical manufacturing industry. Mechanical automation te... With the overall improvement and steady development of Chinas science and technology, mechanical automation technology has been widely used in Chinas current mechanical manufacturing industry. Mechanical automation technology can improve the steady development of industrial enterprises and help enterprises to realize intelligent, intensive and systematic production management work pattern analysis under the current product production cycle structure. At the same time, the comprehensive management of production, implementation of production technology and production speed in the production process of the enterprise can be comprehensively controlled, thus effectively improving the quality of product production management within the enterprise and effectively shortening the actual cycle of product production. Therefore, based on the implementation of the existing mechanical automation technology, this paper analyzes the effective application of mechanical automation technology in the mechanical manufacturing industry, analyzes the main problems existing therein, and puts forward various measures and means accordingly, so as to provide certain assistance for the application of mechanical automation technology in the mechanical manufacturing industry. 展开更多
关键词 mechanical automation technology machinery manufacturing APPLICATION
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Discussion on Existing Problems and Countermeasures of Practical Training Teaching of Mechanical and Electrical Technology Application Major in Secondary Vocational Schools
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作者 CHEN Yanxia 《外文科技期刊数据库(文摘版)教育科学》 2021年第4期146-150,共5页
Secondary vocational schools are one of the cradles for training professional technicians, and the major of electromechanical technology application is a popular major in secondary vocational schools. With the rapid d... Secondary vocational schools are one of the cradles for training professional technicians, and the major of electromechanical technology application is a popular major in secondary vocational schools. With the rapid development of social and economic level, the electromechanical industry has obtained rapid development, and the demand for electromechanical talents is also increasing day by day. Therefore, many secondary vocational students have chosen the major of electromechanical technology application. However, the practical teaching effect of the electromechanical technology application major in secondary vocational schools is not ideal, and there are still some problems. This paper will focus on discussing the existing problems in the practical teaching of the application of mechanical and electrical technology in secondary vocational schools, and put forward specific solutions for reference by teachers of the application of mechanical and electrical technology in secondary vocational schools. 展开更多
关键词 secondary vocational mechanical and electrical technology application major practical teaching EX
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Effects of Rice Combine Harvester Application to Harvest Chinese Milk Vetch Seeds
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作者 廖育林 鲁艳红 +4 位作者 聂军 周兴 谢坚 杨曾平 吴浩杰 《Agricultural Science & Technology》 CAS 2015年第4期853-856,共4页
During the test, the seed yield, Iabor efficiency, harvesting costs and eco-nomic benefits were compared and analyzed between mechanical harvesting tech-noIogy and traditional artificial harvesting technoIogy of Chine... During the test, the seed yield, Iabor efficiency, harvesting costs and eco-nomic benefits were compared and analyzed between mechanical harvesting tech-noIogy and traditional artificial harvesting technoIogy of Chinese miIk vetch seeds to studied the mechanical harvesting technoIogy and appIication effects. The resuIts showed that mechanical harvesting technoIogy increased the yield of 92.7 kg/hm2, reducing the seeds Ioss. It improved the Iabor efficiency and reduced the harvesting cost. For exampIe, a rice combine harvester was the equal of 18-20 person in the harvest quantity in one day, which directIy reduced the Iabor cost of 2 175-3 000 yuan/hm2 and increased the economic income of 3 307-4 099 yuan/hm2. So it wiI pIay an important roIe in soIving the shortage of Chinese miIk vetch seeds and ac-ceIerating the deveIopment of Chinese miIk vetch green manure crop in south China rice region. 展开更多
关键词 Rice combine harvester Chinese mlik vetch seeds Mechanical harvest-ing technology Applicatlon effect
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Pyrolysis characteristics of Radix Rhizoma Rhei, Cortex Moudan Radicis, and Radix Sanguisorbae and correlations with the carbonizing process of Chinese herbs 被引量:8
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作者 MENG Xiang-Long GUO Xiao-Hui +3 位作者 CUI Nan-Nan MA Jun-Nan ZHANG Shuo-Sheng FAN Zhou 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2014年第1期55-64,共10页
AIM: The aim of the work is to study the pyrolysis characteristics of Radix Rhizoma Rhei, Cortex Moudan Radicis, and Radix Sanguisorbae in an inert atmosphere of argon (Ar), and to investigate the mechanism of the ... AIM: The aim of the work is to study the pyrolysis characteristics of Radix Rhizoma Rhei, Cortex Moudan Radicis, and Radix Sanguisorbae in an inert atmosphere of argon (Ar), and to investigate the mechanism of the carbonizing process of the three traditional Chinese herbs. METHODS: The pyrolysis characteristics of the crude materials and their extracts were studied by thermogravimetry-mass spectrometry (TG-MS) in a carrier gas of argon, coupled with Fourier transform infrared spectrometry (FTIR) and scanning electron microscopy (SEM) methods. Correlation of the pyrolysis behaviors with the carbonizing process by stir-frying of traditional Chinese medicines was made. RESULTS: Within the temperature range of 200-300 ℃, which is the testing range for the study of the carbonizing process of Chinese herbs, the temperatures indicated by the maximum weight loss rate peak of the above three extracts were taken as the upper-limit temperatures of the carbonizing process of the herbs, and which were 200, 240 and 247 ℃ for Radix Rhizoma Rhei, Cortex Moudan Radicis, and Radix Sanguisorbae, respectively. The ion monitoring signal peaks detected by the TG-MS method corresponded with reports that the level of chemical components of traditional Chinese medicinal materials would decrease after the carbonizing process. It was confirmed by Fourier transform infrared spectrometry (FTIR) and scanning electron microscopy (SEM) methods that better results of "medicinal property preservation" could be obtained by heating at 200 ℃ for Radix Rhizoma Rhei, at about 250 ℃ for Cortex Moudan Radicis, and Radix Sanguisorbae, as the relative intensity values of the common peaks were among the middle of their three carbonized samples by programmed heating. CONCLUSION: The upper-limit temperatures of the carbonizing process for Radix Rhizoma Rhei, Cortex Moudan Radicis and Radix Sanguisorbae were 200, 240 and 247 ℃ respectively. It is feasible to research the mechanism and technology of the carbonizing process of traditional Chinese medicinal materials using thermogravimetry, Fourier transform infrared spectrometry, and scanning electron microscopy methods. 展开更多
关键词 Chinese materia medica Mechanism and technology of carbonizing process Thermogravimetry-mass spectrometry(TG-MS) Fourier transform infrared spectrometry (FTIR) Scanning electron microscopy (SEM)
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Somatosensory Neuron Typing with High-Coverage Single-Cell RNA Sequencing and Functional Analysis 被引量:5
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作者 Changlin Li Sashuang Wang +1 位作者 Yan Chen Xu Zhang 《Neuroscience Bulletin》 SCIE CAS CSCD 2018年第1期200-207,共8页
Different physical and chemical stimuli are detected by the peripheral sensory receptors of dorsal root ganglion (DRG) neurons, and the generated inputs are transmitted via afferent fibers into the central nervous s... Different physical and chemical stimuli are detected by the peripheral sensory receptors of dorsal root ganglion (DRG) neurons, and the generated inputs are transmitted via afferent fibers into the central nervous system. The gene expression profiles of DRG neurons contribute to the generation, transmission, and regulation of various somatosensory signals. Recently, the single-cell transcriptomes, cell types, and functional annotations of somatosensory neurons have been studied. In this review, we introduce our classification of DRG neurons based on single-cell RNA-sequencing and functional analyses, and discuss the technical approaches. Moreover, studies on the molecular and cellular mechanisms underlying somatic sensations are discussed. 展开更多
关键词 Neuron type Single-cell technology Somatosensory mechanism PAIN Gene profiles
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Mechanics of rib spalling of high coal walls under fully-mechanized mining 被引量:9
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作者 Yuan Yong Tu Shihao +3 位作者 Wu Qi Ma Xiaotao Tu Hongsheng Sun Lulu 《Mining Science and Technology》 EI CAS 2011年第1期129-133,共5页
In order to solve the problem of rib spalling of high coal walls in fully-mechanized(HCWFM)mines,we used the principle of damage mechanics to analyze coal wall rib spalling.The results show that coal wall rib spalling... In order to solve the problem of rib spalling of high coal walls in fully-mechanized(HCWFM)mines,we used the principle of damage mechanics to analyze coal wall rib spalling.The results show that coal wall rib spalling is,to a certain degree,a macro-performance of the development of micro-cracks.We built a mechanical model to simulate the damage to the front of coal walls,carried out theoretical calculations of the damage parameters,analyzed the effect of mining height,original cracks,seam strength,horizontal stress,vertical displacement of the coal walls and other parameters on coal wall rib spalling, which conform well with the results of our field measurements and numerical simulation.The key to control coal wall rib spalling is to control the development of cracks in coal walls.Accelerating the speed of advancing the working face,improving the setting load of support and the horizontal force of the guard board,strengthening coal walls and other technical measures can effectively reduce the degree of damage to the coal walls and control coal wall rib spalling at HCWFM faces. 展开更多
关键词 HCWFM Rib spa/ling Damage mechanics Control technology
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Spatio-temporal Fragmentation of Leisure Activities in Information Era: Empirical Evidence from Nanjing, China 被引量:10
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作者 XI Guangliang ZHEN Feng +1 位作者 Puel GILLES Fernandez VALERIE 《Chinese Geographical Science》 SCIE CSCD 2017年第1期137-150,共14页
Activity fragmentation provides a new approach for understanding the transformation of urban space and function in the information era. Numerous theoretical and empirical studies have been conducted on activity fragme... Activity fragmentation provides a new approach for understanding the transformation of urban space and function in the information era. Numerous theoretical and empirical studies have been conducted on activity fragmentation, but few studies have focused on the fragmentation of leisure activities. This study was intended to extend the extant literature by: 1) analysing the spatio-temporal fragmentation of physical and virtual leisure activities by using a dataset collected in Nanjing, China, and 2) evaluating the reasons of leisure activity fragmentation, as well as the potential spatial effect of activity fragmentation. The results indicated that virtual leisure activities are more fragmented than physical leisure activities, but the fragmentation of physical and virtual leisure activities varies on weekday and weekend, as well as in various locations and urban districts. In addition, the results suggested that sociodemographic factors and information and communication technology(ICT) variables distinctly affect the fragmentation of leisure activities. Meanwhile, the fragmentation of virtual leisure activities may enhance the transformation of traditional urban space by reallocating leisure activity times and locations. 展开更多
关键词 activity fragmentation information and communication technology(ICT) influencing mechanism China
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Effects of Processing Technologies on Mechanical Properties of SiC Particulate Reinforced Magnesium Matrix Composites 被引量:2
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作者 樊建锋 ZHANG Hua +3 位作者 DONG Hongbiao XU Bingshe ZHANG Zhifeng SHI Likai 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2014年第4期769-772,共4页
Mg matrix composites with SiC particles ranging from 5vol%-25vol% were prepared using stirring casting method. Die casting, squeezing casting, and extrusion were applied for inhibiting or eliminating the defects such ... Mg matrix composites with SiC particles ranging from 5vol%-25vol% were prepared using stirring casting method. Die casting, squeezing casting, and extrusion were applied for inhibiting or eliminating the defects such as gas porosity and shrinkage void. Through die casting and squeezing casting, most of the defects in Mg matrix composites could be eliminated, but the mechanical properties were improved limitedly. On the other hand, after hot extrusion, not only most of the defects of as-cast composites ingots were eliminated, but also the mechanical properties were improved markedly. With the addition of SiC, the tensile strength, yield strength and elastic modulus of as extrusion SiCp/AZ61 composites increased remarkably, and the elongation decreased obviously. 展开更多
关键词 Mg matrix composites stirring casting forming technology mechanical property
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In-situ Fabricated TiB_2 Particle-whisker Synergistically Toughened Ti(C,N)-based Ceramic Cutting Tool Material 被引量:4
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作者 LIU Hanlian SHI Qiang +3 位作者 HUANG Chuanzhen ZOU Bin XU Liang WANG Jun 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2015年第2期338-342,共5页
The mechanical properties of ceramic cutting tool materials can be modified by introducing proper content of nanoparticles or whiskers.However,the process of adding whiskers or nanoparticles has the disadvantages of h... The mechanical properties of ceramic cutting tool materials can be modified by introducing proper content of nanoparticles or whiskers.However,the process of adding whiskers or nanoparticles has the disadvantages of high cost and health hazard as well as the agglomeration;although a new in-situ two-step sintering process can solve the above problems to some extent,yet the problems of low conversion ratio of the raw materials and the abnormal grain growth exist in this process.In this paper,an in-situ one-step synthesis technology is proposed,which means the growth of whiskers or nanoparticles and the sintering of the compact can be accomplished by one time in furnace.A kind of Ti(C,N)-based ceramic cutting tool material synergistically toughened by TiB_2 particles and whiskers is fabricated with this new process.The phase compositions,relationships between microstructure and mechanical properties as well as the toughening mechanisms are analyzed by means of X-ray diffraction(XRD)and scanning electron microscopy(SEM).The composite which is sintered under a pressure of 32 MPa at a temperature of 1700℃in vacuum holding for 60 min can get the optimal mechanical properties.Its flexural strength,fracture toughness and Vickers hardness are 540 MPa,7.81 MPa·m(1/2)and 20.42 GPa,respectively.The composite has relatively high density,and the in-situ synthesized TiB_2 whiskers have good surface integrity,which is beneficial for the improvement of the fracture toughness.It is concluded that the main toughening mechanisms of the present composite are whiskers pulling-out and crack deflection induced by whiskers,crack bridging by whiskers/particles and multi-scale particles synergistically toughening.This study proposes an in-situ one-step synthesis technology which can be well used for fabricating particles and whiskers synergistically toughened ceramic tool materials. 展开更多
关键词 in-situ synthesis technology TiB_ whisker toughening mechanism Ti(C N)-TiB_ composite tool material
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Review on Modeling and Optimization for Refractories
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作者 WANG Jiezeng 《China's Refractories》 CAS 2016年第3期25-30,共6页
This paper introduced characteristics of refractories and step of simulation. During simulation,firstly analyzed mechanism of technology; secondly described the mechanism as quadratic equation; thirdly designed and ex... This paper introduced characteristics of refractories and step of simulation. During simulation,firstly analyzed mechanism of technology; secondly described the mechanism as quadratic equation; thirdly designed and executed experiment; later made regression equation and optimization; then found technical conflict; finally analyzed and resolved the conflict. Doing repeatedly like this,resolved difficult problems. 展开更多
关键词 technology mechanism regression equa-tion sensitivity analysis efficiency analysis conflictanalysis
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Fiber reinforced ceramic matrix composites:from the controlled fabrication to precision machining
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作者 Shuoshuo Qu Yuying Yang +3 位作者 Peng Yao Luyao Li Yang Sun Dongkai Chu 《International Journal of Extreme Manufacturing》 2025年第6期118-150,共33页
Fiber reinforced ceramic matrix composites(FRCMCs)are the preferred materials for safety critical components in the fields of aerospace,nuclear engineering,and transportation,with broad market and application prospect... Fiber reinforced ceramic matrix composites(FRCMCs)are the preferred materials for safety critical components in the fields of aerospace,nuclear engineering,and transportation,with broad market and application prospects.However,due to the characteristics of multiphase,heterogeneity,and anisotropy,key issues such as poor adhesion,high porosity,and crack propagation urgently need to be addressed in the fabrication and machining of FRCMCs.With the increasing demand for FRCMCs parts,high-quality and reliable design and fabrication,performance evaluation,and precision manufacturing have become a series of hot issues.There is a lack of systematic review in capturing the current research status and development direction of FRCMCs fabrication and machining.This research aims to comprehensively review and critically evaluate the existing understanding of the fabrication and machining of FRCMCs.This study can provide scientists with a deeper understanding of the shape control mechanism of FRCMCs fabrication and machining,the theoretical basis of material synchronous removal,machining performance,and development direction.Firstly,the basic characteristics and application background of FRCMCs are introduced.Secondly,by comparing and analyzing the typical fabrication process of FRCMCs,the advantages,disadvantages,and performance evaluation of different processes are comprehensively evaluated.Thirdly,the material removal mechanisms and machining performance evaluation standards of traditional mechanical machining technologies(drilling,milling,grinding)and non-traditional mechanical machining technologies(ultrasonic,laser,water jet,discharge,wire saw,and multi-field hybrid machining)are discussed and analyzed.Finally,the challenges,development trends,and prospects faced by FRCMCs in the fields of fabrication,machining,and application are analyzed.This study not only elucidates the basic processes and key difficulties in the fabrication of FRCMCs,but also provides valuable insights for low-damage machining. 展开更多
关键词 fiber reinforced ceramic matrix composites removal mechanism traditional mechanical machining technologies non-traditional mechanical machining technologies
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Flow behavior and deposition study of pollen-shape carrier particles in an idealized inhalation path model 被引量:2
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作者 Meer Saiful Hassan Raymond Lau 《Particuology》 SCIE EI CAS CSCD 2010年第1期51-59,共9页
Pollen-shape (spiked sphere) hydroxyapatite (HA) particles for drug carrier application are studied. The particle shape and size effect on flow characteristics and deposition are assessed. The pollen-shape HA part... Pollen-shape (spiked sphere) hydroxyapatite (HA) particles for drug carrier application are studied. The particle shape and size effect on flow characteristics and deposition are assessed. The pollen-shape HA particles are synthesized to have comparable size as typical carrier particles with mean diameter of 30-50 μm and effective density less than 0.3 g/cm^3. The flow behaviors of HA and commonly used lactose (LA) carrier particles are characterized by the Carr's compressibility index (CI). The HA particles have lower CI than the LA particles for the same size range. The flow fields of HA and LA carrier particles are measured in an idealized inhalation path model using particle image velocimetry (PLY) technique. The particle streamlines indicate that a large portion of particles may deposit at the bending section due to inertial impaction and gravitational deposition. The flow field result shows that HA particles give smaller separation regions than the LA particles for the same size range. The pollen-shape HA particles are found to be able to follow the gas flow in the model and minimize undesired deposition. Deposition result confirms the bending section to have the most deposition. Deposition is found to be a function of particle properties. An empirical correlation is derived for the deposition efficiency of the pollen-shape particles as a function of particles Stokes number. 展开更多
关键词 Aerosol Fluid mechanics Multiphase flow Particle Powder technology Pulmonary drug delivery
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