Diradicaloids have garnered significant attention due to their unique electronic,photophysical properties and potential applications in functional materials.Characterized by a narrow band gap and near-infrared(NIR)abs...Diradicaloids have garnered significant attention due to their unique electronic,photophysical properties and potential applications in functional materials.Characterized by a narrow band gap and near-infrared(NIR)absorption,diradicaloids are promising candidates for NIR-guided photothermal therapy.However,they are often unstable and exhibit non-emissive properties due to high chemical reactivity and very efficient internal conversion.Herein,we report a remarkably stable Chichibabin diradicaloid,TT-CzPh,which exhibits NIR luminescence(λ_(em)=821 nm)with an efficient photoluminescence quantum yield(PLQY)of 6.4%.Surprisingly,TT-CzPh not only exhibits excellent NIR imaging but also has a very high photothermal conversion efficiency(PCE)of 87.5%.In vivo experiments with TT-CzPh nanoparticles demonstrated their effectiveness in tumor photoablation guided by NIR imaging.This work not only advances the development of stable,efficient luminescent Chichibabin’s hydrocarbons but also opens new avenues for bioimaging and cancer phototherapy applications.展开更多
Optical spectroscopy is crucial for understanding the optical properties of materials,characterizing the performance of photonic devices,and monitoring industrial processes based on spectral detection[1–3].However,co...Optical spectroscopy is crucial for understanding the optical properties of materials,characterizing the performance of photonic devices,and monitoring industrial processes based on spectral detection[1–3].However,commercial spectrometers often involve intricate optical setups and have substantial physical dimensions,especially for spectrometers with high precision.Consequently,there is a motivation to develop miniaturized spectrometers with increasement in portability and environmental robustness,which will broaden the scope of information acquisition in both scientific research and industrial applications[4].展开更多
基金supported by the National Key R&D Program of China(No.2023YFB3208303)the National Natural Science Foundation of China(Grant Nos.62422404,62171194,52103210)the Natural Science Foundation of Jilin Province(No.20230101363JC).
文摘Diradicaloids have garnered significant attention due to their unique electronic,photophysical properties and potential applications in functional materials.Characterized by a narrow band gap and near-infrared(NIR)absorption,diradicaloids are promising candidates for NIR-guided photothermal therapy.However,they are often unstable and exhibit non-emissive properties due to high chemical reactivity and very efficient internal conversion.Herein,we report a remarkably stable Chichibabin diradicaloid,TT-CzPh,which exhibits NIR luminescence(λ_(em)=821 nm)with an efficient photoluminescence quantum yield(PLQY)of 6.4%.Surprisingly,TT-CzPh not only exhibits excellent NIR imaging but also has a very high photothermal conversion efficiency(PCE)of 87.5%.In vivo experiments with TT-CzPh nanoparticles demonstrated their effectiveness in tumor photoablation guided by NIR imaging.This work not only advances the development of stable,efficient luminescent Chichibabin’s hydrocarbons but also opens new avenues for bioimaging and cancer phototherapy applications.
基金supported by the National Key Research and Development Program of China(2021YFA1400800)the Quantum Science Strategic Initiative(GDZX2206001 and GDZX2306003)+2 种基金the Natural Science Foundation of Guangdong Province(2022B1515020067 and 2024B1515040013)the Postdoctoral Fellowship Program of CPSF(GZB20240909)the China Postdoctoral Science Foundation(2024M763733)。
文摘Optical spectroscopy is crucial for understanding the optical properties of materials,characterizing the performance of photonic devices,and monitoring industrial processes based on spectral detection[1–3].However,commercial spectrometers often involve intricate optical setups and have substantial physical dimensions,especially for spectrometers with high precision.Consequently,there is a motivation to develop miniaturized spectrometers with increasement in portability and environmental robustness,which will broaden the scope of information acquisition in both scientific research and industrial applications[4].
