Background:Allogeneic peripheral-blood stem-cell transplantation(SCT)from a matched related donor after myeloablative conditioning is the preferred curative treatment for patients with high-risk blood cancers.The comb...Background:Allogeneic peripheral-blood stem-cell transplantation(SCT)from a matched related donor after myeloablative conditioning is the preferred curative treatment for patients with high-risk blood cancers.The combination of a calcineurin inhibitor and an antimetabolite remains standard care for graft-versus-host disease(GVHD)prophylaxis in these patients.Data from two randomized trials have suggested that post-transplantation cyclophosphamide can reduce the risk of GVHD after SCT from a matched donor when it is added to or replaces the antimetabolite.展开更多
A relational matching approach for imagery-to-GIS data is presented. This method applies image aspect interpretation and geospatial data mining techniques to realize their integration. Three-dimensional (3D) primiti...A relational matching approach for imagery-to-GIS data is presented. This method applies image aspect interpretation and geospatial data mining techniques to realize their integration. Three-dimensional (3D) primitives, standing for houses, are chosen and their projections are represented by these aspects. The hierarchy aspect graphs are constructed to represent their intercon- nected relations. In this connection arcs are described by attribute data via formulated coding regulations. The nodes of the graph represent image features and their attributes can contain measurements on these features. The arcs of the graph represent relations between features and their attributes can contain measurements on spatial relations. Data mining is used to discover the semantic relationship of these primitives. Aerial images are interpreted via these aspects and geospatial data mining. Our experimental results demonstrate that the method oresented is cat)able of effectively interoreting aerial images and extracting high accuracv from the DBM (digital building model) at a rate of 87%.展开更多
Based on hydromachanics and the law of conservation of energy by means of the Bernoulli Equation, the matching relation of a pump pressure and delivery, losing energy of the magma when it flows along the pipes are res...Based on hydromachanics and the law of conservation of energy by means of the Bernoulli Equation, the matching relation of a pump pressure and delivery, losing energy of the magma when it flows along the pipes are researched. This thesis provide the theoretical basis for equipment selection and selection of pipeline.展开更多
Allogeneic hematopoietic stem cell transplantation(HSCT)is one of the most effective options for hematological malignancies,and human leukocyte antigen-partially matched related donors(PMRDs)are a valuable option for ...Allogeneic hematopoietic stem cell transplantation(HSCT)is one of the most effective options for hematological malignancies,and human leukocyte antigen-partially matched related donors(PMRDs)are a valuable option for HSCT.Several protocols(with or without ex vivo T-cell depletion(TCD))have been established worldwide.TCD including CD34+positive selection and CD3/CD19 depletion has successfully overcome the human leukocyte antigen disparity.However,TCD is associated with prolonged immune deficiencies,increased risks of infectious complications,and high transplantation-related mortality.PMRD HSCT without ex vivo TCD is well developed,and numerous patients have benefitted from it.Here,we review the literature on PMRD HSCT.展开更多
文摘Background:Allogeneic peripheral-blood stem-cell transplantation(SCT)from a matched related donor after myeloablative conditioning is the preferred curative treatment for patients with high-risk blood cancers.The combination of a calcineurin inhibitor and an antimetabolite remains standard care for graft-versus-host disease(GVHD)prophylaxis in these patients.Data from two randomized trials have suggested that post-transplantation cyclophosphamide can reduce the risk of GVHD after SCT from a matched donor when it is added to or replaces the antimetabolite.
基金Projects 40574008 supported by the National Natural Science Foundation of China0131893 by the US National Science Foundation
文摘A relational matching approach for imagery-to-GIS data is presented. This method applies image aspect interpretation and geospatial data mining techniques to realize their integration. Three-dimensional (3D) primitives, standing for houses, are chosen and their projections are represented by these aspects. The hierarchy aspect graphs are constructed to represent their intercon- nected relations. In this connection arcs are described by attribute data via formulated coding regulations. The nodes of the graph represent image features and their attributes can contain measurements on these features. The arcs of the graph represent relations between features and their attributes can contain measurements on spatial relations. Data mining is used to discover the semantic relationship of these primitives. Aerial images are interpreted via these aspects and geospatial data mining. Our experimental results demonstrate that the method oresented is cat)able of effectively interoreting aerial images and extracting high accuracv from the DBM (digital building model) at a rate of 87%.
文摘Based on hydromachanics and the law of conservation of energy by means of the Bernoulli Equation, the matching relation of a pump pressure and delivery, losing energy of the magma when it flows along the pipes are researched. This thesis provide the theoretical basis for equipment selection and selection of pipeline.
基金This work was partly supported by the National High Technology Research and Development Program of China(863 Program)(Grant No.2011AA020105)the Key Program of National Natural Science Foundation of China(Grant No.81230013).
文摘Allogeneic hematopoietic stem cell transplantation(HSCT)is one of the most effective options for hematological malignancies,and human leukocyte antigen-partially matched related donors(PMRDs)are a valuable option for HSCT.Several protocols(with or without ex vivo T-cell depletion(TCD))have been established worldwide.TCD including CD34+positive selection and CD3/CD19 depletion has successfully overcome the human leukocyte antigen disparity.However,TCD is associated with prolonged immune deficiencies,increased risks of infectious complications,and high transplantation-related mortality.PMRD HSCT without ex vivo TCD is well developed,and numerous patients have benefitted from it.Here,we review the literature on PMRD HSCT.