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Exploring hard-rock cutting performances by a master-slave follow-up disc cutter
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作者 Feng Lin Xia-Ting Feng +3 位作者 Yuxi Liu Shiping Li Tianyang Tong Xiangxin Su 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第12期7966-7979,共14页
In this paper,a self-developed master-slave follow-up disc cutter is used to conduct rock-breaking tests on hard sandstone samples.Different working parameters were employed in the tests(e.g.cutting depth,cutting spee... In this paper,a self-developed master-slave follow-up disc cutter is used to conduct rock-breaking tests on hard sandstone samples.Different working parameters were employed in the tests(e.g.cutting depth,cutting speed,cutting angle,and rotational speed)in order to explore their influences on cutting performance.The results indicate that the thrust,torque,vibration velocity,and roughness all increased continuously with increase of the propulsion speed and cutting depth.At the same time,the specific energy consumption was found to decrease continuously.As the rotational speed was increased,the thrust increased at first and then decreased.In contrast,the torque and roughness continuously decreased,and the specific energy consumption and vibration speed continuously increased.When the cutting angle was increased,the thrust remained unchanged.However,the torque,specific energy consumption,and vibration speed all decreased continuously,and the roughness increased continuously.The temperature of the surface of the cutting tool was found to be relatively uniformly distributed during the rock-breaking process;the highest temperatures generated were in the range of 200-300℃.As the propulsion speed,cutting depth,and cutting angle were increased,the proportion of tensile fractures produced appeared to increase and the proportion of shear fractures decreased.As the rotational speed was increased,the proportion of tensile fractures decreased and the proportion of shear fractures increased.The results could provide useful information on the rock-breaking behavior involved and can be used to offer technical support for engineers using master-slave follow-up disc cutters in the field. 展开更多
关键词 Hard rocks master-slave follow-up cutter Specific energy consumption Rock-breaking mechanism
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Cluster synchronization of master-slave complex networks via adaptive feedback pinning control
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作者 LIU Ziping GONG Siyi 《上海师范大学学报(自然科学版中英文)》 2025年第4期389-400,共12页
This paper investigates the problem of cluster synchronization of master-slave complex net-works with time-varying delay via linear and adaptive feedback pinning controls.We need not non-delayed and delayed coupling m... This paper investigates the problem of cluster synchronization of master-slave complex net-works with time-varying delay via linear and adaptive feedback pinning controls.We need not non-delayed and delayed coupling matrices to be symmetric or irreducible.We have the advantages of using adaptive control method to reduce control gain and pinning control technology to reduce cost.By con-structing Lyapunov function,some sufficient synchronization criteria are established.Finally,numerical examples are employed to illustrate the effectiveness of the proposed approach. 展开更多
关键词 cluster synchronization TIME-VARYING master-slave complex networks DELAYED adaptive feedback control pinning control
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Master-Slave机器手协调控制选择行列式算法
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作者 杨慧 《中国民航学院学报》 2003年第A02期210-213,共4页
提出了一种基于选择行列式的Master-Slave机器手的协调控制算法。通过选择行列式的导入,实现了对Master机器手和Slave机器手各个变量的协调控制。本方法应用于装有视觉传感器的机器手的追踪控制,经过实验证明了基于选择行列式的算法能... 提出了一种基于选择行列式的Master-Slave机器手的协调控制算法。通过选择行列式的导入,实现了对Master机器手和Slave机器手各个变量的协调控制。本方法应用于装有视觉传感器的机器手的追踪控制,经过实验证明了基于选择行列式的算法能够实现人类的某些技能赋予机器手,在支援机器手的同时还能够通过有效地协调遥控,完成机器手的自主控制。 展开更多
关键词 选择行列式 master-slave机器手 协调控制 视觉传感器
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A Master-Slave Blockchain Paradigm and Application in Digital Rights Management 被引量:5
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作者 Zhaofeng Ma Weihua Huang +2 位作者 Wei Bi Hongmin Gao Zhen Wang 《China Communications》 SCIE CSCD 2018年第8期174-188,共15页
Upon flaws of current blockchain platforms of heavyweight, large capacity of ledger, and time-consuming of synchronization of data, in this paper, we proposed a new paradigm of master-slave blockchain scheme(MSB) for ... Upon flaws of current blockchain platforms of heavyweight, large capacity of ledger, and time-consuming of synchronization of data, in this paper, we proposed a new paradigm of master-slave blockchain scheme(MSB) for pervasive computing that suitable for general PC, mobile device such as smart phones or PADs to participants in the working of mining and verification, in which we separated traditional blockchain model in 2 layer defined as master node layer and a series of slavery agents layer, then we proposed 2 approaches for partially computing model(PCM) and non-computing of model(NCM) in the MSB blockchain, Finally large amounts of simulations manifest the proposed master-slave blockchain scheme is feasible, extendible and suitable for pervasive computing especially in the 5 G generation environment, and can apply in the DRM-related applications. 展开更多
关键词 master-slave blockchain proof ofequivalent work proof of contribution pervasive computing DRM application
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Achievement of chaotic synchronization trajectories of master-slave manipulators with feedback control strategy 被引量:3
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作者 Qingkai Han Lina Hao Hao Zhang Bangchun Wen 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2010年第3期433-439,共7页
This paper addresses a master-slave synchro- nization strategy for complex dynamic systems based on feedback control. This strategy is applied to 3-DOF pla- nar manipulators in order to obtain synchronization in such ... This paper addresses a master-slave synchro- nization strategy for complex dynamic systems based on feedback control. This strategy is applied to 3-DOF pla- nar manipulators in order to obtain synchronization in such complicated as chaotic motions of end-effectors. A chaotic curve is selected from Duffing equation as the trajectory of master end-effector and a piecewise approximation method is proposed to accurately represent this chaotic trajectory of end-effectors. The dynamical equations of master-slave manipulators with synchronization controller are derived, and the Lyapunov stability theory is used to determine the stability of this controlled synchronization system. In numer- ical experiments, the synchronous motions of end-effectors as well as three joint angles and torques of master-slave manipulators are studied under the control of the proposed synchronization strategy. It is found that the positive gain matrix affects the implementation of synchronization con- trol strategy. This synchronization control strategy proves the synchronization's feasibility and controllability for com- plicated motions generated by master-slave manipulators. 展开更多
关键词 master-slave manipulators - Chaoticsynchronization trajectory - Feedback control
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Exponential networked synchronization of master-slave chaotic systems with timevarying communication topologies 被引量:1
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作者 杨东升 刘振伟 +1 位作者 赵琰 刘兆冰 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第4期151-158,共8页
The networked synchronization problem of a class of master-slave chaotic systems with time-varying communication topologies is investigated in this paper. Based on algebraic graph theory and matrix theory, a simple li... The networked synchronization problem of a class of master-slave chaotic systems with time-varying communication topologies is investigated in this paper. Based on algebraic graph theory and matrix theory, a simple linear state feedback controller is designed to synchronize the master chaotic system and the slave chaotic systems with a time- varying communication topology connection. The exponential stability of the closed-loop networked synchronization error system is guaranteed by applying Lyapunov stability theory. The derived novel criteria are in the form of linear matrix inequalities (LMIs), which are easy to examine and tremendously reduce the computation burden from the feedback matrices. This paper provides an alternative networked secure communication scheme which can be extended conveniently. An illustrative example is given to demonstrate the effectiveness of the proposed networked synchronization method. 展开更多
关键词 exponential networked synchronization master-slave chaotic systems algebraic graph theory communication topology
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基于WOA-VMD和PSO-DSN的短期时空光伏功率预测
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作者 赵英男 彭真 阮玉园 《计算机系统应用》 2025年第8期264-275,共12页
由于太阳能具有间歇性、不稳定性和随机性,精确的短期光伏(photovoltaic,PV)功率预测具有较大的挑战,阻碍了光伏与智能电网的有机整合.为此,本文提出了一种名为WVPD(WOA-VMD和PSO-DSN)的方法.首先,应用变分模态分解(variational mode de... 由于太阳能具有间歇性、不稳定性和随机性,精确的短期光伏(photovoltaic,PV)功率预测具有较大的挑战,阻碍了光伏与智能电网的有机整合.为此,本文提出了一种名为WVPD(WOA-VMD和PSO-DSN)的方法.首先,应用变分模态分解(variational mode decomposition,VMD)获得多个本征模态函数(intrinsic mode function,IMF)分量.同时,结合鲸鱼优化算法(whale optimization algorithm,WOA)算法进行模式分量和惩罚因子参数优化,解决VMD分解不足和模式混合问题.然后,利用PV功率和数值天气预报(numerical weather prediction,NWP)数据的空间和时间相关性构建新型双流网络(dual-stream network,DSN),即结合挤压和激励网络(squeeze-andexcitation networks,SENet)以及双向门控循环单元(bidirectional gated recurrent unit,BiGRU).同时,采用粒子群优化算法(particle swarm optimization,PSO)优化DSN中学习率和批量大小.最后,验证得出与深度学习混合模型相比,MSE平均提升78.6%,RMSE平均提升53.7%,MAE平均提升37.7%,所提出的WVPD性能优越.代码共享于https://github.com/ruanyuyuan/PV-power-forecast. 展开更多
关键词 光伏功率预测 变分模态分解 双流网络 鲸鱼优化算法 粒子群优化
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A master-slave generalized predictive synchronization control for preheating process of multi-cavity hot runner system 被引量:1
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作者 Hongyi Qu Shengyong Mo +3 位作者 Ke Yao Zhao-Xia Huang Zhihao Xu Furong Gao 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第10期270-280,共11页
As a key component of injection molding,multi-cavity hot runner(MCHR)system faces the crucial problem of polymer melt filling imbalance among the cavities.The thermal imbalance in the system has been considered as the... As a key component of injection molding,multi-cavity hot runner(MCHR)system faces the crucial problem of polymer melt filling imbalance among the cavities.The thermal imbalance in the system has been considered as the leading cause.Hence,the solution may rest with the synchronization of those heating processes in MCHR system.This paper proposes a’Master-Slave’generalized predictive synchronization control(MS-GPSC)method with’Mr.Slowest’strategy for preheating stage of MCHR system.The core of the proposed method is choosing the heating process with slowest dynamics as the’Master’to track the setpoint,while the other heating processes are treated as‘Slaves’tracking the output of’Master’.This proposed method is shown to have the good ability of temperature synchronization.The corresponding analysis is conducted on parameters tuning and stability,simulations and experiments show the strategy is effective. 展开更多
关键词 Process control Thermodynamics process Model-predictive control Multi-cavity hot runner system master-slave synchronization Mr.Slowest
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基于迭代加权虚拟力算法的DSNs覆盖增强
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作者 高睿 冯秀芳 《太原理工大学学报》 北大核心 2017年第3期475-480,共6页
针对现有有向传感器网络(DSNs)覆盖增强算法复杂且收敛速度较慢的问题,在方向可调的有向感知模型基础上,提出一种基于分布式迭代加权的虚拟力覆盖增强算法(IW-RFGP)的有向传感器节点部署方法。该方法将传感器节点待感知区域内未被邻接... 针对现有有向传感器网络(DSNs)覆盖增强算法复杂且收敛速度较慢的问题,在方向可调的有向感知模型基础上,提出一种基于分布式迭代加权的虚拟力覆盖增强算法(IW-RFGP)的有向传感器节点部署方法。该方法将传感器节点待感知区域内未被邻接节点覆盖的区域离散化,通过离散网格点的迭代加权引力的合力作用,调整并确定其新的感知方向。仿真实验结果表明,该算法收敛速度快,迭代次数短,有效增强了有向传感器网络的覆盖率。 展开更多
关键词 有向传感器网络 覆盖增强 虚拟力 加权
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Research on Master-slave Telerobot Force Telepresence Technology
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作者 蔡鹤皋 陈卫东 +1 位作者 贾国武 赵杰 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 1997年第4期69-72,共4页
A 3 DOF master-slave telerobot system is established for study on force telepresence technology. A force feedback and position control scheme is adopted in the bilateral force response control system,and force fidelit... A 3 DOF master-slave telerobot system is established for study on force telepresence technology. A force feedback and position control scheme is adopted in the bilateral force response control system,and force fidelity and controllability experiments demonstrate feasibility of the con-trol system. 展开更多
关键词 master-slave TELEROBOT FORCE TELEPRESENCE BILATERAL FORCE response control MANOEUVRABILITY
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Jet sweeping angle control by fluidic oscillators with master-slave designs
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作者 Ziyan LI Kaiwen ZHOU +1 位作者 Yingzheng LIU Xin WEN 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2021年第5期145-162,共18页
The fluidic oscillator is an instrument that can continuously generate a spatially sweeping jet entirely based on its internal geometry without any moving parts.However,the traditional fluidic oscillator has an inhere... The fluidic oscillator is an instrument that can continuously generate a spatially sweeping jet entirely based on its internal geometry without any moving parts.However,the traditional fluidic oscillator has an inherent limitation,that is,the spreading angle cannot be controlled independently,rather by the jet volume flow rate and internal geometry.Accordingly,two types of fluidic oscillators based on the master-slave design are developed in current study to decouple this correlation.In both designs,the master layer inherits the similar oscillation mechanisms of a sweeping jet,and the slave layer resembles a steady jet channel.The difference between the two designs is that Design A has a short diverging exit in the slave layer,but Design B adds a long interaction chamber in the exit channel to intensify flow instability.The external flow fields and governing oscillation properties of these two designs are experimentally explored with time-resolved Particle Image Velocimetry(PIV),while the internal flow dynamics and driving oscillation mechanisms are numerically investigated.By fixing the total volume flow rate,the jet spreading angle of Design A can be increased smoothly from 0°to above 100°by increasing the proportion of master layer’s flow rate from 0 to 100%.For Design B,the control authority of the master layer is significantly enhanced by adding the interaction chamber in the slave layer.In addition,the added chamber causes notable jet oscillation even when the master layer has none input. 展开更多
关键词 Adjustable spreading angle CFD Fluidic devices master-slave fluidic oscillator TR-PIV
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Adaptive H_∞ Synchronization of Master-slave Systems with Mixed Time-varying Delays and Nonlinear Perturbations: An LMI Approach
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作者 Hamid Reza Karimi 《International Journal of Automation and computing》 EI 2011年第4期381-390,共10页
This paper proposes an adaptive synchronization problem for the master and slave structure of linear systems with nonlinear perturbations and mixed time-varying delays comprising different discrete and distributed tim... This paper proposes an adaptive synchronization problem for the master and slave structure of linear systems with nonlinear perturbations and mixed time-varying delays comprising different discrete and distributed time delays. Using an appropriate Lyapunov-Krasovskii functional, some delay-dependent sufficient conditions and an adaptation law including the master-slave parame- ters are established for designing a delayed synchronization law in terms of linear matrix inequalities(LMIs). The time-varying controller guarantees the H ∞ synchronization of the two coupled master and slave systems regardless of their initial states. Particularly, it is shown that the synchronization speed can be controlled by adjusting the updated gain of the synchronization signal. Two numerical examples are given to demonstrate the effectiveness of the method. 展开更多
关键词 Adaptive synchronization master-slave systems DELAY H performance nonlinear perturbations.
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Tremor suppression in master-slave robot remote welding system
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作者 陈洪堂 李海超 +1 位作者 高洪明 吴林 《China Welding》 EI CAS 2011年第2期63-66,共4页
Welding seam tracking precision was decreased due to human hand tremor during the master-slave welding teleoperation. To solve this problem, a master-slave robot remote welding system was built, the system consisted o... Welding seam tracking precision was decreased due to human hand tremor during the master-slave welding teleoperation. To solve this problem, a master-slave robot remote welding system was built, the system consisted of a master manipulator with six degree of freedom ( DOF ) , an industrial computer control system and a slave Motoman HP3 J robot, and human hand tremor and digital filtering were discussed. An optimal digital filter was designed to clean human tremor signal for improving the welding seam tracking precision. The experimental results show that the digital filter suppresses the operator' s tremor signal. 展开更多
关键词 remote welding master-slave teleoperation hand tremor digital filtering
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Hierarchical hybrid control network design based on LON and master-slave RS-422/485 protocol
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作者 彭可 陈际达 陈岚 《Journal of Central South University of Technology》 2002年第3期202-207,共6页
Aiming at the weaknesses of LON bus, combining the coexistence of fieldbus and DCS (Distribu ted Control Systems) in control networks, the authors introduce a hierarchical hybrid control network design based on LON an... Aiming at the weaknesses of LON bus, combining the coexistence of fieldbus and DCS (Distribu ted Control Systems) in control networks, the authors introduce a hierarchical hybrid control network design based on LON and master slave RS 422/485 protocol. This design adopts LON as the trunk, master slave RS 422/485 control networks are connected to LON as special subnets by dedicated gateways. It is an implementation method for isomerous control network integration. Data management is ranked according to real time requirements for different network data. The core components, such as control network nodes, router and gateway, are detailed in the paper. The design utilizes both communication advantage of LonWorks technology and the more powerful control ability of universal MCUs or PLCs, thus it greatly increases system response speed and performance cost ratio. 展开更多
关键词 LON fieldbus master-slave RS-422/485 PROTOCOL HIERARCHICAL hybrid control NETWORKS router gateway NETWORKS integration
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Distributed Generation Islanding Effect on Distribution Networks and End User Loads Using the Master-Slave Islanding Method
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作者 Lambros Ekonomou George P. Fotis +1 位作者 Vasiliki Vita Valeri Mladenov 《Journal of Power and Energy Engineering》 2016年第10期1-24,共24页
This study aims to address the feasibility of planned islanding operation and to investigate the effect of unplanned islanding using the master-slave islanding method for controlling the distributed generation units d... This study aims to address the feasibility of planned islanding operation and to investigate the effect of unplanned islanding using the master-slave islanding method for controlling the distributed generation units during grid-connected and islanding operation. Neplan desktop power simulation tool was used for the modelling and simulation of a realistic MV network with four different distributed generation technologies (diesel, gas, hydro and wind) along with their excitation and governor control systems, while an exponential model was used to represent the loads in the network. The dynamic and steady state behavior of the four distributed generation technologies were investigated during grid-connected operation and two transition modes to the islanding situation, planned and unplanned. The obtained results that validated through various case studies have shown that a suitable planned islanding transition could provide support to critical loads at the event of electricity utility outages. 展开更多
关键词 Distributed Generation Distribution Networks ISLANDING master-slave Islanding Method Neplan Simulation Tool
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Content Addressable Memory Using Automatic Charge Balancing with Self-Control Mechanism and Master-Slave Match Line Design
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作者 Dr. Deepa Jose P. Suganya Dr. Palanichamy Nirmal Kumar 《Circuits and Systems》 2016年第6期597-611,共15页
Content Addressable Memory (CAM) is a type of memory used for high-speed search applications. Due to parallel comparison feature, the CAM memory leads to large power consumption which is caused by frequent pre-charge ... Content Addressable Memory (CAM) is a type of memory used for high-speed search applications. Due to parallel comparison feature, the CAM memory leads to large power consumption which is caused by frequent pre-charge or discharge of match line. In this paper, CAM for automatic charge balancing with self-control mechanism is proposed to control the voltage swing of ML for reducing the power consumption of CAM. Another technique to reduce the power dissipation is to use MSML, it combines the master-slave architecture with charge minimization technique. Unlike the conventional design, only one match line (ML) is used, whereas in Master-Slave Match Line (MSML) one master ML and several slave MLs are used to reduce the power dissipation in CAM caused by match lines (MLs). Theoretically, the match line (ML) reduces the power consumption up to 50% which is independent of search and match case. The simulation results using Cadence tool of MSML show the reduced power consumption in CAM and modified CAM cell. 展开更多
关键词 Content Addressable Memory (CAM) Match Line (ML) master-slave Match Line (MSML) Charge Balance Translation Look-Aside Buffer (TLAB)
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JSP中使用非DSN的ODBC连接方式实现多种数据库间的访问 被引量:3
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作者 刘承启 李建民 《计算机与现代化》 2005年第11期84-86,107,共4页
通过一个研究生学院信息管理系统实例的设计开发过程,分析探讨了JSP页面上不使用DSN,结合文件操作的方式,实现多种数据库系统互访的方法。
关键词 JSP JDBC-ODBC桥 dsn FOXPRO SQL server
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三阴性乳腺癌组织中DSN1的表达变化及其与预后的关系 被引量:2
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作者 全秀莲 朱金明 +2 位作者 陈曦 张宇 冀学宁 《山东医药》 CAS 2020年第25期82-85,共4页
目的观察三阴性乳腺癌患者癌组织中DSN1的表达变化,并探讨其与预后的关系。方法选择120例三阴性乳腺癌患者,采用免疫组化法检测乳腺癌组织中的DSN1,并根据免疫组化结果将患者分为DSN1高表达者与低表达者,分析DSN1表达与三阴性乳腺癌临... 目的观察三阴性乳腺癌患者癌组织中DSN1的表达变化,并探讨其与预后的关系。方法选择120例三阴性乳腺癌患者,采用免疫组化法检测乳腺癌组织中的DSN1,并根据免疫组化结果将患者分为DSN1高表达者与低表达者,分析DSN1表达与三阴性乳腺癌临床病理特征的关系,比较DSN1高低表达者无瘤生存率和总生存率的差异,采用Cox比例风险模型分析影响乳腺癌无瘤生存率和总生存率的独立危险因素。结果120例患者中75.8%(91/120)DSN1高表达、24.2%(29/120)DSN1低表达。三阴性乳腺癌组织中DSN1表达与TNM分期和淋巴结转移有关(P均<0.05)。DSN1高表达者无瘤生存率和总生存率均低于DSN1低表达者(P均<0.01)。多因素Cox回归分析表明,DSN1表达(HR=1.091,95%CI:1.082~3.75,P=0.001)是三阴性乳腺癌患者无瘤生存率独立预测因子,DSN1表达(HR=1.887,95%CI:1.591~4.528,P=0.003)、TNM分期(HR=1.368,95%CI:0.577~2.734,P=0.013)可作为三阴性乳腺癌患者总生存率的预测因子。结论DSN1在三阴性乳腺癌组织中高表达,且与患者TNM分期和淋巴结转移密切相关;DSN1高表达是三阴性乳腺癌预后不良的独立危险因素,可能是预测三阴性乳腺癌预后新的分子标志物。 展开更多
关键词 三阴性乳腺癌 dsn1基因 生存时间 预后
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基于IMS的DSN P2P流媒体系统 被引量:1
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作者 吴亦川 彭晋 段晓东 《移动通信》 2010年第8期66-70,共5页
文章介绍了基于IMS的DSN P2P流媒体系统的研究背景,简述了基于IMS的流媒体标准化进展;提出了一种面向电信运营商的可控可管的基于IMS的DSN P2P流媒体系统架构;介绍了系统的测试环境,并通过模型分析评估了DSN P2P流媒体业务对IMS网络的... 文章介绍了基于IMS的DSN P2P流媒体系统的研究背景,简述了基于IMS的流媒体标准化进展;提出了一种面向电信运营商的可控可管的基于IMS的DSN P2P流媒体系统架构;介绍了系统的测试环境,并通过模型分析评估了DSN P2P流媒体业务对IMS网络的性能影响。 展开更多
关键词 dsn P2P流媒体 IMS 可控可管
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肝组织中ARID4B和DSN1蛋白表达水平在肝细胞癌患者预后评估中的价值
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作者 闫春伟 田立蕊 张璐 《国际消化病杂志》 CAS 2020年第6期423-430,共8页
目的探索ARID家族富含AT的相互作用域4B(ARID4B)以及Nnf1的剂量抑制因子(DSN1)蛋白表达水平在肝细胞癌(HCC)患者预后评估中的作用。方法使用癌症基因组图谱(TCGA)和基因表达数据库(GEO)中的数据来分析HCC中ARID4B和DSN1的表达。所有组... 目的探索ARID家族富含AT的相互作用域4B(ARID4B)以及Nnf1的剂量抑制因子(DSN1)蛋白表达水平在肝细胞癌(HCC)患者预后评估中的作用。方法使用癌症基因组图谱(TCGA)和基因表达数据库(GEO)中的数据来分析HCC中ARID4B和DSN1的表达。所有组织样本均取自2016年6月至2017年6月在秦皇岛市第三医院外科接受肝切除手术且术前未行化学治疗或放射治疗的HCC患者。取新鲜冷冻的130对HCC组织和邻近非癌肝组织(ANLT)样品,采用实时定量聚合酶链反应(real-time qPCR)检测ARID4B mRNA和DSN1 mRNA的表达水平。对130例经37%甲醛溶液固定、石蜡包埋的HCC组织样品进行免疫组织化学分析,以检测ARID4B和DSN1在HCC组织中的表达水平并确定其临床意义。结果生物信息学分析、RT-PCR结果表明,与ANLT相比,ARID4B和DSN1在HCC组织中高表达(P<0.05)。ARID4B高表达与肿瘤结节数(P=0.042)、TNM分期(P=0.001)密切相关。DSN1高表达与性别(P=0.035)、甲胎蛋白(AFP)(P=0.005)、肿瘤结节数(P=0.023)密切相关。此外,Kaplan-Meier和Cox比例风险分析表明,ARID4B和DSN1高表达与HCC患者的不良生存率显著相关,并且ARID4B和DSN1是HCC患者整体生存和无病生存的独立预后因素。结论ARID4B和DSN1可作为预测HCC患者预后的生物学标志物。 展开更多
关键词 肝细胞癌 ARID4B dsn1 总体生存率 无病生存率
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