The International GNSS Service(IGS) final products(ephemeris and clocks-correction) have made the GNSS an indispensable low-cost tool for scientific research, for example sub-daily atmospheric water vapor monitoring. ...The International GNSS Service(IGS) final products(ephemeris and clocks-correction) have made the GNSS an indispensable low-cost tool for scientific research, for example sub-daily atmospheric water vapor monitoring. In this study, we investigate if there is a systematic difference coming from the choice between the Vienna Mapping Function 1(VMF1) and the Global Mapping Function(GMF) for the modeling of Zenith Total Delay(ZTD) estimates, as well as the Integrated Precipitable Water Vapor(IPWV) estimates that are deduced from them. As ZTD estimates cannot be fully separated from coordinate estimates, we also investigated the coordinate repeatability between subsequent measurements.For this purpose, we monitored twelve GNSS stations on a global scale, for each of the three climatic zones(polar, mid-latitudes and tropical), with four stations on each zone. We used an automated processing based on the Bernese GNSS Software Version 5.2 by applying the Precise Point Positioning(PPP)approach, L3 Ionosphere-free linear combination, 7 cutoff elevation angle and 2 h sampling. We noticed an excellent agreement with the ZTD estimates and coordinate repeatability for all the stations w.r.t to CODE(the Center for Orbit Determination in Europe) and USNO(US Naval Observatory) products, except for the Antarctic station(Davis) which shows systematic biases for the GMF related results. As a final step, we investigated the effect of using two mapping functions(VMF1 and GMF) to estimate the IPWV,w.r.t the IPWV estimates provided by the Integrated Global Radiosonde Archive(IGRA). The GPS-derived IPWV estimates are very close to the radiosonde-derived IPWV estimates, except for one station in the tropics(Tahiti).展开更多
Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends a...Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends and knowledge structures for human neural stem cells have not yet been studied bibliometrically.In this study,we retrieved 2742 articles from the PubMed database from 2013 to 2018 using "Neural Stem Cells" as the retrieval word.Co-word analysis was conducted to statistically quantify the characteristics and popular themes of human neural stem cell-related studies.Bibliographic data matrices were generated with the Bibliographic Item Co-Occurrence Matrix Builder.We identified 78 high-frequency Medical Subject Heading(MeSH)terms.A visual matrix was built with the repeated bisection method in gCLUTO software.A social network analysis network was generated with Ucinet 6.0 software and GraphPad Prism 5 software.The analyses demonstrated that in the 6-year period,hot topics were clustered into five categories.As suggested by the constructed strategic diagram,studies related to cytology and physiology were well-developed,whereas those related to neural stem cell applications,tissue engineering,metabolism and cell signaling,and neural stem cell pathology and virology remained immature.Neural stem cell therapy for stroke and Parkinson’s disease,the genetics of microRNAs and brain neoplasms,as well as neuroprotective agents,Zika virus,Notch receptor,neural crest and embryonic stem cells were identified as emerging hot spots.These undeveloped themes and popular topics are potential points of focus for new studies on human neural stem cells.展开更多
We have defined the environmental interface through the exchange processes between media forming this interface. Considering the environmental interface as a complex system we elaborated the advanced mathematical tool...We have defined the environmental interface through the exchange processes between media forming this interface. Considering the environmental interface as a complex system we elaborated the advanced mathematical tools for its modelling. We have suggested two coupled maps serving the exchange processes on the environmental interfaces spatially ranged from cellular to planetary level, i.e. 1) the map with diffusive coupling for energy exchange simulation and 2) the map with affinity, which is suitable for matter exchange processes at the cellular level. We have performed the dynamical analysis of the coupled maps using the Lyapunov exponent, cross sample as well as the permutation entropy in dependence on different map parameters. Finally, we discussed the map with affinity, which shows some features making it a promising toll in simulation of exchange processes on the environmental interface at the cellular level.展开更多
Automatic segmentation and recognition of content and element information in color geological map are of great significance for researchers to analyze the distribution of mineral resources and predict disaster informa...Automatic segmentation and recognition of content and element information in color geological map are of great significance for researchers to analyze the distribution of mineral resources and predict disaster information.This article focuses on color planar raster geological map(geological maps include planar geological maps,columnar maps,and profiles).While existing deep learning approaches are often used to segment general images,their performance is limited due to complex elements,diverse regional features,and complicated backgrounds for color geological map in the domain of geoscience.To address the issue,a color geological map segmentation model is proposed that combines the Felz clustering algorithm and an improved SE-UNet deep learning network(named GeoMSeg).Firstly,a symmetrical encoder-decoder structure backbone network based on UNet is constructed,and the channel attention mechanism SENet has been incorporated to augment the network’s capacity for feature representation,enabling the model to purposefully extract map information.The SE-UNet network is employed for feature extraction from the geological map and obtain coarse segmentation results.Secondly,the Felz clustering algorithm is used for super pixel pre-segmentation of geological maps.The coarse segmentation results are refined and modified based on the super pixel pre-segmentation results to obtain the final segmentation results.This study applies GeoMSeg to the constructed dataset,and the experimental results show that the algorithm proposed in this paper has superior performance compared to other mainstream map segmentation models,with an accuracy of 91.89%and a MIoU of 71.91%.展开更多
We reported in this manuscript that TGF-beta1 induces apoptosis in AML12 murine hepatocytes, which is associated with the activation of p38 MAPK signaling pathway. SB202190, a specific inhibitor of p38 MAPK, strongly ...We reported in this manuscript that TGF-beta1 induces apoptosis in AML12 murine hepatocytes, which is associated with the activation of p38 MAPK signaling pathway. SB202190, a specific inhibitor of p38 MAPK, strongly inhibited the TGF-beta1-induced apoptosis and PAI-1 promoter activity. Treatment of cells with TGF-beta1 activates p38. Furthermore, over-expression of dominant negative mutant p38 also reduced the TGF-beta1-induced apoptosis. The data indicate that the activation of p38 is involved in TGF-beta1-mediated gene expression and apoptosis.展开更多
The Kehdolan area is located at 20 kilometers to the?south-east of Dozdozan Town (Eastern Azarbaijan Province). According to structural geology, volconic rocks are situated in Alborz-Azarbyjan zone, and faults?are?obs...The Kehdolan area is located at 20 kilometers to the?south-east of Dozdozan Town (Eastern Azarbaijan Province). According to structural geology, volconic rocks are situated in Alborz-Azarbyjan zone, and faults?are?observed?in?the?same direction to this system with SE-NW trend. The results show that kaolinite alteration trend with Argilic and propylitic veins?is the?same direction with SW-NE faults in this area. Therefore, these faults with these trends can be considered as the mineralization control for determination of the alterations. Different image processing techniques,?such as false color composite?(FCC), band ratios, color ratio composite?(CRC), principal component?analysis?(PCA), Crosta technique, supervised spectral angle mapping?(SAM), are used for?identification of the alteration zones associated with copper mineralization. In this project ASTER?data are process and spectral analysis to fit for recognizing intensity and kind of argillic, propylitic,?philic, and ETM+ data?which?are process and to fit for iron oxide and relation to metal mineralization of the area. For recognizing different alterations of the study area, some chemical and mineralogical analysis data from the samples showed that ASTER data and ETM+ data were?capable of hydrothermal alteration mapping with copper mineralization.?Copper mineralization in the region is in agreement with argillic alteration. SW-NE trending faults controlled the mineralization process.展开更多
Conventional soil maps(CSMs)often have multiple soil types within a single polygon,which hinders the ability of machine learning to accurately predict soils.Soil disaggregation approaches are commonly used to improve ...Conventional soil maps(CSMs)often have multiple soil types within a single polygon,which hinders the ability of machine learning to accurately predict soils.Soil disaggregation approaches are commonly used to improve the spatial and attribute precision of CSMs.The approach disaggregation and harmonization of soil map units through resampled classification trees(DSMART)is popular but computationally intensive,as it generates and assigns synthetic samples to soil series based on the areal coverage information of CSMs.Alternatively,the disaggregation approach pure polygon disaggregation(PPD)assigns soil series based solely on the proportions of soil series in pure polygons in CSMs.This study compared these two disaggregation approaches by applying them to a CSM of Middlesex County,Ontario,Canada.Four different sampling methods were used:two sampling designs,simple random sampling(SRS)and conditional Latin hypercube sampling(cLHS),with two sample sizes(83100 and 19420 samples per sampling plan),both based on an area-weighted approach.Two machine learning algorithms(MLAs),C5.0 decision tree(C5.0)and random forest(RF),were applied to the disaggregation approaches to compare the disaggregation accuracy.The accuracy assessment utilized a set of 500 validation points obtained from the Middlesex County soil survey report.The MLA C5.0(Kappa index=0.58–0.63)showed better performance than RF(Kappa index=0.53–0.54)based on the larger sample size,and PPD with C5.0 based on the larger sample size was the best-performing(Kappa index=0.63)approach.Based on the smaller sample size,both cLHS(Kappa index=0.41–0.48)and SRS(Kappa index=0.40–0.47)produced similar accuracy results.The disaggregation approach PPD exhibited lower processing capacity and time demands(1.62–5.93 h)while yielding maps with lower uncertainty as compared to DSMART(2.75–194.2 h).For CSMs predominantly composed of pure polygons,utilizing PPD for soil series disaggregation is a more efficient and rational choice.However,DSMART is the preferable approach for disaggregating soil series that lack pure polygon representations in the CSMs.展开更多
TNNI3K is a cardiac-specific and cardiac troponin I(cT n I)-interacting MAP kinase, known to play important roles in promoting cardiac differentiation, maintenance of beating rhythm and contractual force. The molecula...TNNI3K is a cardiac-specific and cardiac troponin I(cT n I)-interacting MAP kinase, known to play important roles in promoting cardiac differentiation, maintenance of beating rhythm and contractual force. The molecular structure of TNNI3 K contains three kinds of domain: a seven or ten NH2-terminal ankyrin repeat domain followed by a protein kinase domain and a COOH-terminal serine-rich domain. There are many binding sites in the structure of TNNI3 K for binding to ATP, magnesium, nucleotide, protein kinase C, antioxidant protein 1(AOP-1) and cT n I, indicating TNNI3 K has many interacting partners. This review summarizes the evidence, hypothesis and significance of TNNI3 K interacting with TNNI3 and its other putative interaction partners. From the literature, the interaction partners of TNNI3 K are divided into 2 types following their phenotypic pattern of functions, positive interaction(to increase the cardiac performance) or negative interaction(to suppress the cardiac performance). Following their binding sites, it also can be divided into other 2 types: binding to C-terminal domain(e.g., cT n I) or binding to both ankyrin repeat domain and C-terminal domains(AOP-1).To date, a well understood partner of TNNI3 K is cT nI, from the molecular structure, physiological function, mechanisms and its significance in some physiological and pathophysiological conditions. There are many reasons to believe that, with more understanding on the TNNI3 K interacting with its partners, we can understand more roles of TNNI3 K in some cardiac diseases.展开更多
The African continent habituated with volatile conflicts and protracted violence,be it intra-state or inter-state is also acquainted with multi-ethnic tensions breeding different militias.The trend,although not new,is...The African continent habituated with volatile conflicts and protracted violence,be it intra-state or inter-state is also acquainted with multi-ethnic tensions breeding different militias.The trend,although not new,is the expanding phenomenon of Jihadism and general terrorism.Some of these and other forms of conflicts summarize the geopolitics of Africa’s Great Lakes Region(AGLR).The bloodbath wherein the subregion engrosses itself is not solely guided by political considerations.Both endogenous and exogenous capitalist economic profit have stirred the system while ethnic politics and politics on ethnic leanings have amplified the scenario.The endeavors of both the international community and regional blocs appear deficient-a consequence of the frailty of the UN system and general multilateralism.Peace is possible for AGLR when humanity is placed over the tidal wave of capitalist profit,patriotism over toxic ethnicity and respect is accorded to international jurisprudence emblemed by the bona fide principle of pacta sunt Servanda,without neglecting the capacity of the youth and peace education.展开更多
The paper reviews goals and objectives, stages and components of a seismotectonic study conducted in Eastern Siberia, Russia. Based on a comprehensive analysis of geological and geophysical data, our study establishes...The paper reviews goals and objectives, stages and components of a seismotectonic study conducted in Eastern Siberia, Russia. Based on a comprehensive analysis of geological and geophysical data, our study establishes whether the local earthquakes are of tectonic origin and reveals relationships among earthquakes with recent geodynamic processes in the area under study. Seismic hazard assessment and evaluation of tectonic processes are the two major closely interrelated aspects of seismotectonic studies. A seismotectonic study is generally combined with a seismic study and conducted prior to the stage of detailed seismic zonation (DSZ) which is followed by seismic micro-zonation (SMZ). In three stages of the seismotectonic study, we analyze specific geological structures, reveal the regional dynamics of seismotectonic processes, clarify details of potential seismic hazard locations and identify sites of the potential instantaneous deformation of the crust which may take place due to active faulting. Based on results of our longterm studies, a seismotectonic zonation map of Eastern Siberia is compiled. The paper briefly reviews the methods of mapping and refers to data on active faults and neotectonic structures revealed in the area under study, which are closely related to regional earthquake sources.展开更多
Stream cipher, DNA cryptography and DNA analysis are the most important R&D fields in both Cryptography and Bioinformatics. HC-256 is an emerged scheme as the new generation of stream ciphers for advanced network ...Stream cipher, DNA cryptography and DNA analysis are the most important R&D fields in both Cryptography and Bioinformatics. HC-256 is an emerged scheme as the new generation of stream ciphers for advanced network security. From a random sequencing viewpoint, both sequences of HC-256 and real DNA data may have intrinsic pseudo-random properties respectively. In a recent decade, many DNA sequencing projects are developed on cells, plants and animals over the world into huge DNA databases. Researchers notice that mammalian genomes encode thousands of large noncoding RNAs (lncRNAs), interact with chromatin regulatory complexes, and are thought to play a role in localizing these complexes to target loci across the genome. It is a challenge target using higher dimensional visualization tools to organize various complex interactive properties as visual maps. The Variant Map System (VMS) as an emerging scheme is systematically proposed in this paper to apply multiple maps that used four Meta symbols as same as DNA or RNA representations. System architecture of key components and core mechanism on the VMS are described. Key modules, equations and their I/O parameters are discussed. Applying the VM System, two sets of real DNA sequences from both sample human (noncoding DNA) and corn (coding DNA) genomes are collected in comparison with pseudo DNA sequences generated by HC-256 to show their intrinsic properties in higher levels of similar relationships among relevant DNA sequences on 2D maps. Sample 2D maps are listed and their characteristics are illustrated under controllable environment. Visual results are briefly analyzed to explore their intrinsic properties on selected genome sequences.展开更多
This contribution proposes a new combination symbol mapper/8-ary constellation, which is a joint optimization of an 8-ary signal constellation and its symbol mapping operation, to improve the performance of Bit Interl...This contribution proposes a new combination symbol mapper/8-ary constellation, which is a joint optimization of an 8-ary signal constellation and its symbol mapping operation, to improve the performance of Bit Interleaved Coded Modulation with Iterative Decoding (BICM-ID). The basic idea was to use the so called (1,7) constellation (which is a capacitive efficient constellation) instead of the conventional 8-PSK constellation and to choose the most suitable mapping for it. A comparative study between the combinations most suitable mapping/(1,7) constellation and SSP mapping/conventional 8-PSK constellation has been carried out. Simulation results showed that the 1st combination significantly outperforms the 2nd combination and with only 4 iterations, it gives better performance than the 2nd combination with 8 iterations. A gain of 4 dB is given by iteration 4 of the 1st combination compared to iteration 8 of the 2nd combination at a BER level equal to 10-5, and it (iteration 4 of the 1st combination) can attain a BER equal to 10-7 for, only, a SNR = 5.6 dB.展开更多
On April 28,2023,the Map Museum of Zhengzhou University was officially opened in the historical Central Plains of China.The museum was founded by Mr.GAO Jun,Distinguished Academician of the Chinese Academy of Sciences...On April 28,2023,the Map Museum of Zhengzhou University was officially opened in the historical Central Plains of China.The museum was founded by Mr.GAO Jun,Distinguished Academician of the Chinese Academy of Sciences and Dean of the School of Geo-Science and Technology at Zhengzhou University.The establishment of the Map Museum reflects the vigorous development of Chinese cartography and its advancement toward world-class level.Additionally,it marks a significant milestone in promoting Chinese map culture.展开更多
Dear Editor,The mammalian brain exhibits cross-scale complexity in neuronal morphology and connectivity,the study of which demands high-resolution morphological reconstruction of individual neurons across the entire b...Dear Editor,The mammalian brain exhibits cross-scale complexity in neuronal morphology and connectivity,the study of which demands high-resolution morphological reconstruction of individual neurons across the entire brain[1-4].Current commonly used approaches for such mesoscale brain mapping include two main types of three-dimensional fluorescence microscopy:the block-face methods,and the lightsheet-based methods[5,6].In general,the high imaging speed and light efficiency of light-sheet microscopy make it a suitable tool for high-throughput volumetric imaging,especially when combined with tissue-clearing techniques.However,large brain samples pose major challenges to this approach.展开更多
基金the innovation carrier project by Zhejiang provincial science and Technology Department (2017F10008)the French Space Agency (CNES) for their funding, through a DAR grant to the Geodesy Observatory of Tahiti
文摘The International GNSS Service(IGS) final products(ephemeris and clocks-correction) have made the GNSS an indispensable low-cost tool for scientific research, for example sub-daily atmospheric water vapor monitoring. In this study, we investigate if there is a systematic difference coming from the choice between the Vienna Mapping Function 1(VMF1) and the Global Mapping Function(GMF) for the modeling of Zenith Total Delay(ZTD) estimates, as well as the Integrated Precipitable Water Vapor(IPWV) estimates that are deduced from them. As ZTD estimates cannot be fully separated from coordinate estimates, we also investigated the coordinate repeatability between subsequent measurements.For this purpose, we monitored twelve GNSS stations on a global scale, for each of the three climatic zones(polar, mid-latitudes and tropical), with four stations on each zone. We used an automated processing based on the Bernese GNSS Software Version 5.2 by applying the Precise Point Positioning(PPP)approach, L3 Ionosphere-free linear combination, 7 cutoff elevation angle and 2 h sampling. We noticed an excellent agreement with the ZTD estimates and coordinate repeatability for all the stations w.r.t to CODE(the Center for Orbit Determination in Europe) and USNO(US Naval Observatory) products, except for the Antarctic station(Davis) which shows systematic biases for the GMF related results. As a final step, we investigated the effect of using two mapping functions(VMF1 and GMF) to estimate the IPWV,w.r.t the IPWV estimates provided by the Integrated Global Radiosonde Archive(IGRA). The GPS-derived IPWV estimates are very close to the radiosonde-derived IPWV estimates, except for one station in the tropics(Tahiti).
基金supported by the National Natural Science Foundation of China,No.81471308(to JL)the Stem Cell Clinical Research Project in China,No.CMR-20161129-1003(to JL)the Innovation Technology Funding of Dalian in China,No.2018J11CY025(to JL)
文摘Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends and knowledge structures for human neural stem cells have not yet been studied bibliometrically.In this study,we retrieved 2742 articles from the PubMed database from 2013 to 2018 using "Neural Stem Cells" as the retrieval word.Co-word analysis was conducted to statistically quantify the characteristics and popular themes of human neural stem cell-related studies.Bibliographic data matrices were generated with the Bibliographic Item Co-Occurrence Matrix Builder.We identified 78 high-frequency Medical Subject Heading(MeSH)terms.A visual matrix was built with the repeated bisection method in gCLUTO software.A social network analysis network was generated with Ucinet 6.0 software and GraphPad Prism 5 software.The analyses demonstrated that in the 6-year period,hot topics were clustered into five categories.As suggested by the constructed strategic diagram,studies related to cytology and physiology were well-developed,whereas those related to neural stem cell applications,tissue engineering,metabolism and cell signaling,and neural stem cell pathology and virology remained immature.Neural stem cell therapy for stroke and Parkinson’s disease,the genetics of microRNAs and brain neoplasms,as well as neuroprotective agents,Zika virus,Notch receptor,neural crest and embryonic stem cells were identified as emerging hot spots.These undeveloped themes and popular topics are potential points of focus for new studies on human neural stem cells.
文摘We have defined the environmental interface through the exchange processes between media forming this interface. Considering the environmental interface as a complex system we elaborated the advanced mathematical tools for its modelling. We have suggested two coupled maps serving the exchange processes on the environmental interfaces spatially ranged from cellular to planetary level, i.e. 1) the map with diffusive coupling for energy exchange simulation and 2) the map with affinity, which is suitable for matter exchange processes at the cellular level. We have performed the dynamical analysis of the coupled maps using the Lyapunov exponent, cross sample as well as the permutation entropy in dependence on different map parameters. Finally, we discussed the map with affinity, which shows some features making it a promising toll in simulation of exchange processes on the environmental interface at the cellular level.
基金financially supported by the Natural Science Foundation of China(42301492)the Open Fund of Hubei Key Laboratory of Intelligent Vision Based Monitoring for Hydroelectric Engineering(2022SDSJ04,2024SDSJ03)+1 种基金the Opening Fund of Key Laboratory of Geological Survey and Evaluation of Ministry of Education(GLAB 2023ZR01,GLAB2024ZR08)the Fundamental Research Funds for the Central Universities.
文摘Automatic segmentation and recognition of content and element information in color geological map are of great significance for researchers to analyze the distribution of mineral resources and predict disaster information.This article focuses on color planar raster geological map(geological maps include planar geological maps,columnar maps,and profiles).While existing deep learning approaches are often used to segment general images,their performance is limited due to complex elements,diverse regional features,and complicated backgrounds for color geological map in the domain of geoscience.To address the issue,a color geological map segmentation model is proposed that combines the Felz clustering algorithm and an improved SE-UNet deep learning network(named GeoMSeg).Firstly,a symmetrical encoder-decoder structure backbone network based on UNet is constructed,and the channel attention mechanism SENet has been incorporated to augment the network’s capacity for feature representation,enabling the model to purposefully extract map information.The SE-UNet network is employed for feature extraction from the geological map and obtain coarse segmentation results.Secondly,the Felz clustering algorithm is used for super pixel pre-segmentation of geological maps.The coarse segmentation results are refined and modified based on the super pixel pre-segmentation results to obtain the final segmentation results.This study applies GeoMSeg to the constructed dataset,and the experimental results show that the algorithm proposed in this paper has superior performance compared to other mainstream map segmentation models,with an accuracy of 91.89%and a MIoU of 71.91%.
基金supported by the grants from the Major Program of the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(No.23KJA180005)the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX23_3384)。
基金grants fromthe Chinese Academy of Sciences (No. KJ951-BI608), the National Natural Sciences FOundation ofChina (No. 39625007 and
文摘We reported in this manuscript that TGF-beta1 induces apoptosis in AML12 murine hepatocytes, which is associated with the activation of p38 MAPK signaling pathway. SB202190, a specific inhibitor of p38 MAPK, strongly inhibited the TGF-beta1-induced apoptosis and PAI-1 promoter activity. Treatment of cells with TGF-beta1 activates p38. Furthermore, over-expression of dominant negative mutant p38 also reduced the TGF-beta1-induced apoptosis. The data indicate that the activation of p38 is involved in TGF-beta1-mediated gene expression and apoptosis.
文摘The Kehdolan area is located at 20 kilometers to the?south-east of Dozdozan Town (Eastern Azarbaijan Province). According to structural geology, volconic rocks are situated in Alborz-Azarbyjan zone, and faults?are?observed?in?the?same direction to this system with SE-NW trend. The results show that kaolinite alteration trend with Argilic and propylitic veins?is the?same direction with SW-NE faults in this area. Therefore, these faults with these trends can be considered as the mineralization control for determination of the alterations. Different image processing techniques,?such as false color composite?(FCC), band ratios, color ratio composite?(CRC), principal component?analysis?(PCA), Crosta technique, supervised spectral angle mapping?(SAM), are used for?identification of the alteration zones associated with copper mineralization. In this project ASTER?data are process and spectral analysis to fit for recognizing intensity and kind of argillic, propylitic,?philic, and ETM+ data?which?are process and to fit for iron oxide and relation to metal mineralization of the area. For recognizing different alterations of the study area, some chemical and mineralogical analysis data from the samples showed that ASTER data and ETM+ data were?capable of hydrothermal alteration mapping with copper mineralization.?Copper mineralization in the region is in agreement with argillic alteration. SW-NE trending faults controlled the mineralization process.
基金the Ontario Ministry of Agriculture,Food and Rural Affairs,Canada,who supported this project by providing updated soil information on Ontario and Middlesex Countysupported by the Natural Science and Engineering Research Council of Canada(No.RGPIN-2014-4100)。
文摘Conventional soil maps(CSMs)often have multiple soil types within a single polygon,which hinders the ability of machine learning to accurately predict soils.Soil disaggregation approaches are commonly used to improve the spatial and attribute precision of CSMs.The approach disaggregation and harmonization of soil map units through resampled classification trees(DSMART)is popular but computationally intensive,as it generates and assigns synthetic samples to soil series based on the areal coverage information of CSMs.Alternatively,the disaggregation approach pure polygon disaggregation(PPD)assigns soil series based solely on the proportions of soil series in pure polygons in CSMs.This study compared these two disaggregation approaches by applying them to a CSM of Middlesex County,Ontario,Canada.Four different sampling methods were used:two sampling designs,simple random sampling(SRS)and conditional Latin hypercube sampling(cLHS),with two sample sizes(83100 and 19420 samples per sampling plan),both based on an area-weighted approach.Two machine learning algorithms(MLAs),C5.0 decision tree(C5.0)and random forest(RF),were applied to the disaggregation approaches to compare the disaggregation accuracy.The accuracy assessment utilized a set of 500 validation points obtained from the Middlesex County soil survey report.The MLA C5.0(Kappa index=0.58–0.63)showed better performance than RF(Kappa index=0.53–0.54)based on the larger sample size,and PPD with C5.0 based on the larger sample size was the best-performing(Kappa index=0.63)approach.Based on the smaller sample size,both cLHS(Kappa index=0.41–0.48)and SRS(Kappa index=0.40–0.47)produced similar accuracy results.The disaggregation approach PPD exhibited lower processing capacity and time demands(1.62–5.93 h)while yielding maps with lower uncertainty as compared to DSMART(2.75–194.2 h).For CSMs predominantly composed of pure polygons,utilizing PPD for soil series disaggregation is a more efficient and rational choice.However,DSMART is the preferable approach for disaggregating soil series that lack pure polygon representations in the CSMs.
文摘TNNI3K is a cardiac-specific and cardiac troponin I(cT n I)-interacting MAP kinase, known to play important roles in promoting cardiac differentiation, maintenance of beating rhythm and contractual force. The molecular structure of TNNI3 K contains three kinds of domain: a seven or ten NH2-terminal ankyrin repeat domain followed by a protein kinase domain and a COOH-terminal serine-rich domain. There are many binding sites in the structure of TNNI3 K for binding to ATP, magnesium, nucleotide, protein kinase C, antioxidant protein 1(AOP-1) and cT n I, indicating TNNI3 K has many interacting partners. This review summarizes the evidence, hypothesis and significance of TNNI3 K interacting with TNNI3 and its other putative interaction partners. From the literature, the interaction partners of TNNI3 K are divided into 2 types following their phenotypic pattern of functions, positive interaction(to increase the cardiac performance) or negative interaction(to suppress the cardiac performance). Following their binding sites, it also can be divided into other 2 types: binding to C-terminal domain(e.g., cT n I) or binding to both ankyrin repeat domain and C-terminal domains(AOP-1).To date, a well understood partner of TNNI3 K is cT nI, from the molecular structure, physiological function, mechanisms and its significance in some physiological and pathophysiological conditions. There are many reasons to believe that, with more understanding on the TNNI3 K interacting with its partners, we can understand more roles of TNNI3 K in some cardiac diseases.
文摘The African continent habituated with volatile conflicts and protracted violence,be it intra-state or inter-state is also acquainted with multi-ethnic tensions breeding different militias.The trend,although not new,is the expanding phenomenon of Jihadism and general terrorism.Some of these and other forms of conflicts summarize the geopolitics of Africa’s Great Lakes Region(AGLR).The bloodbath wherein the subregion engrosses itself is not solely guided by political considerations.Both endogenous and exogenous capitalist economic profit have stirred the system while ethnic politics and politics on ethnic leanings have amplified the scenario.The endeavors of both the international community and regional blocs appear deficient-a consequence of the frailty of the UN system and general multilateralism.Peace is possible for AGLR when humanity is placed over the tidal wave of capitalist profit,patriotism over toxic ethnicity and respect is accorded to international jurisprudence emblemed by the bona fide principle of pacta sunt Servanda,without neglecting the capacity of the youth and peace education.
文摘The paper reviews goals and objectives, stages and components of a seismotectonic study conducted in Eastern Siberia, Russia. Based on a comprehensive analysis of geological and geophysical data, our study establishes whether the local earthquakes are of tectonic origin and reveals relationships among earthquakes with recent geodynamic processes in the area under study. Seismic hazard assessment and evaluation of tectonic processes are the two major closely interrelated aspects of seismotectonic studies. A seismotectonic study is generally combined with a seismic study and conducted prior to the stage of detailed seismic zonation (DSZ) which is followed by seismic micro-zonation (SMZ). In three stages of the seismotectonic study, we analyze specific geological structures, reveal the regional dynamics of seismotectonic processes, clarify details of potential seismic hazard locations and identify sites of the potential instantaneous deformation of the crust which may take place due to active faulting. Based on results of our longterm studies, a seismotectonic zonation map of Eastern Siberia is compiled. The paper briefly reviews the methods of mapping and refers to data on active faults and neotectonic structures revealed in the area under study, which are closely related to regional earthquake sources.
文摘Stream cipher, DNA cryptography and DNA analysis are the most important R&D fields in both Cryptography and Bioinformatics. HC-256 is an emerged scheme as the new generation of stream ciphers for advanced network security. From a random sequencing viewpoint, both sequences of HC-256 and real DNA data may have intrinsic pseudo-random properties respectively. In a recent decade, many DNA sequencing projects are developed on cells, plants and animals over the world into huge DNA databases. Researchers notice that mammalian genomes encode thousands of large noncoding RNAs (lncRNAs), interact with chromatin regulatory complexes, and are thought to play a role in localizing these complexes to target loci across the genome. It is a challenge target using higher dimensional visualization tools to organize various complex interactive properties as visual maps. The Variant Map System (VMS) as an emerging scheme is systematically proposed in this paper to apply multiple maps that used four Meta symbols as same as DNA or RNA representations. System architecture of key components and core mechanism on the VMS are described. Key modules, equations and their I/O parameters are discussed. Applying the VM System, two sets of real DNA sequences from both sample human (noncoding DNA) and corn (coding DNA) genomes are collected in comparison with pseudo DNA sequences generated by HC-256 to show their intrinsic properties in higher levels of similar relationships among relevant DNA sequences on 2D maps. Sample 2D maps are listed and their characteristics are illustrated under controllable environment. Visual results are briefly analyzed to explore their intrinsic properties on selected genome sequences.
文摘This contribution proposes a new combination symbol mapper/8-ary constellation, which is a joint optimization of an 8-ary signal constellation and its symbol mapping operation, to improve the performance of Bit Interleaved Coded Modulation with Iterative Decoding (BICM-ID). The basic idea was to use the so called (1,7) constellation (which is a capacitive efficient constellation) instead of the conventional 8-PSK constellation and to choose the most suitable mapping for it. A comparative study between the combinations most suitable mapping/(1,7) constellation and SSP mapping/conventional 8-PSK constellation has been carried out. Simulation results showed that the 1st combination significantly outperforms the 2nd combination and with only 4 iterations, it gives better performance than the 2nd combination with 8 iterations. A gain of 4 dB is given by iteration 4 of the 1st combination compared to iteration 8 of the 2nd combination at a BER level equal to 10-5, and it (iteration 4 of the 1st combination) can attain a BER equal to 10-7 for, only, a SNR = 5.6 dB.
文摘On April 28,2023,the Map Museum of Zhengzhou University was officially opened in the historical Central Plains of China.The museum was founded by Mr.GAO Jun,Distinguished Academician of the Chinese Academy of Sciences and Dean of the School of Geo-Science and Technology at Zhengzhou University.The establishment of the Map Museum reflects the vigorous development of Chinese cartography and its advancement toward world-class level.Additionally,it marks a significant milestone in promoting Chinese map culture.
基金supported by the STI 2030-Major Project(2021ZD0204400,2022ZD0205203,2021ZD0200104,2022ZD0211900)the Shenzhen Science and Technology Program(RCYX20210706092100003,RCBS20221008093311027)+3 种基金the Shenzhen Medical Research Funds(A2303005)the Youth Innovation Promotion Association CAS(2022367)the National Natural Science Foundation of China(32100896)NSFC-Guangdong Joint Fund(U20A6005).
文摘Dear Editor,The mammalian brain exhibits cross-scale complexity in neuronal morphology and connectivity,the study of which demands high-resolution morphological reconstruction of individual neurons across the entire brain[1-4].Current commonly used approaches for such mesoscale brain mapping include two main types of three-dimensional fluorescence microscopy:the block-face methods,and the lightsheet-based methods[5,6].In general,the high imaging speed and light efficiency of light-sheet microscopy make it a suitable tool for high-throughput volumetric imaging,especially when combined with tissue-clearing techniques.However,large brain samples pose major challenges to this approach.
