To the Editor:Papillary thyroid carcinoma(PTC)is the most common endocrine malignancy,and an excellent long-term prognosis is attained in most patients.[1]However,aggressive variants of PTC,including tall cells,column...To the Editor:Papillary thyroid carcinoma(PTC)is the most common endocrine malignancy,and an excellent long-term prognosis is attained in most patients.[1]However,aggressive variants of PTC,including tall cells,columnar cells,insular cells,solid cells,and diffuse sclerosing subtypes,are associated with higher recurrence and reduced survival rates.[2]The role of radioactive iodine(RAI)therapy in managing these aggressive variants remains controversial,particularly regarding its impact on cancer-specific survival(CSS).[3]展开更多
文摘To the Editor:Papillary thyroid carcinoma(PTC)is the most common endocrine malignancy,and an excellent long-term prognosis is attained in most patients.[1]However,aggressive variants of PTC,including tall cells,columnar cells,insular cells,solid cells,and diffuse sclerosing subtypes,are associated with higher recurrence and reduced survival rates.[2]The role of radioactive iodine(RAI)therapy in managing these aggressive variants remains controversial,particularly regarding its impact on cancer-specific survival(CSS).[3]
