针对风机偏航转速传感器在长期运行中受偏航旋转工况影响易出现供电不连续与电压波动的问题,开展基于有限电源(Limited Power Source,LPS)冗余供电的稳定性改造应用研究。通过在传感器供电侧引入LPS冗余供电方式,从供电连续性增强、供...针对风机偏航转速传感器在长期运行中受偏航旋转工况影响易出现供电不连续与电压波动的问题,开展基于有限电源(Limited Power Source,LPS)冗余供电的稳定性改造应用研究。通过在传感器供电侧引入LPS冗余供电方式,从供电连续性增强、供电波动抑制及转速信号稳定输出3个方面分析LPS冗余供电在稳定性改造方面的应用,并结合工程实例对改造效果进行对比分析。结果表明,引入LPS冗余供电能够有效提升偏航转速传感器运行稳定性,具有良好的工程应用价值。展开更多
Dysregulated inflammation and multi-organ failure are hallmarks of sepsis,a potentially fatal illness for which there are currently no effective treatments.Fatty acid-binding protein(A-FABP)has been identified in rece...Dysregulated inflammation and multi-organ failure are hallmarks of sepsis,a potentially fatal illness for which there are currently no effective treatments.Fatty acid-binding protein(A-FABP)has been identified in recent research as a crucial mediator of the inflammatory pathways underlying sepsis.In this study,we used a murine model of lipopolysaccharide(LPS)-induced endotoxemia to assess the therapeutic potential of 6H2,a monoclonal antibody that targets A-FABP.In comparison to untreated septic mice,6H2 treatment significantly increased survival rates,decreased histopathological damage in the liver,lungs,kidneys,and heart,and reduced systemic inflammation.According to biochemical analyses,6H2 treatment decreased circulating levels of A-FABP,and this was associated with a reduction in inflammatory markers.These results indicate that A-FABP inhibition is a potentially effective treatment approach for sepsis,with 6H2 demonstrating strong therapeutic efficacy.展开更多
文摘针对风机偏航转速传感器在长期运行中受偏航旋转工况影响易出现供电不连续与电压波动的问题,开展基于有限电源(Limited Power Source,LPS)冗余供电的稳定性改造应用研究。通过在传感器供电侧引入LPS冗余供电方式,从供电连续性增强、供电波动抑制及转速信号稳定输出3个方面分析LPS冗余供电在稳定性改造方面的应用,并结合工程实例对改造效果进行对比分析。结果表明,引入LPS冗余供电能够有效提升偏航转速传感器运行稳定性,具有良好的工程应用价值。
文摘Dysregulated inflammation and multi-organ failure are hallmarks of sepsis,a potentially fatal illness for which there are currently no effective treatments.Fatty acid-binding protein(A-FABP)has been identified in recent research as a crucial mediator of the inflammatory pathways underlying sepsis.In this study,we used a murine model of lipopolysaccharide(LPS)-induced endotoxemia to assess the therapeutic potential of 6H2,a monoclonal antibody that targets A-FABP.In comparison to untreated septic mice,6H2 treatment significantly increased survival rates,decreased histopathological damage in the liver,lungs,kidneys,and heart,and reduced systemic inflammation.According to biochemical analyses,6H2 treatment decreased circulating levels of A-FABP,and this was associated with a reduction in inflammatory markers.These results indicate that A-FABP inhibition is a potentially effective treatment approach for sepsis,with 6H2 demonstrating strong therapeutic efficacy.
