A mathematical model of quantum noise having much effect on the low light imaging system is set up. To simulate the quantum noise, the random numbers obeying noise distribution must be formed and are weighted on the...A mathematical model of quantum noise having much effect on the low light imaging system is set up. To simulate the quantum noise, the random numbers obeying noise distribution must be formed and are weighted on the basis of the model created. Three uniform random sequences are built by the linear congruential method, of which two are used to form integer number and decimal fraction parts of the new random sequence respectively and the third to shuffle the new sequence. And then a Gauss sequence is formed out of uniform distribution by a function transforming method. It actualizes the simulation in real time of quantum noise in the low light imaging system, where video flow is extracted in real time, the noise summed up and played back side by side with the original video signs by a simulation software.展开更多
on the basis of analyzing the characteristics of low light level(LLL)image and ultra-violet image and the information amount of dual channel color night vision system,the LLL and ultra-violet color night vision techni...on the basis of analyzing the characteristics of low light level(LLL)image and ultra-violet image and the information amount of dual channel color night vision system,the LLL and ultra-violet color night vision technique is put forward.The methods of gray-scale modulation,frequency field fusion,special component fusion arc tried,and the improved LLL and ultra-violet image pseudo color fusion algorithms are presented.These new algorithms include subsection gray-scale modulation,image difference picking-up,component separation based on the reflected characteristics to night skylight reflection characteristics of objects and color space mapping which embodies the spectrum response of image sensor and nature vision.Some good results are obtained.展开更多
A novel frame shift and integral technique for the enhancement of low light level moving image sequence is introduced. According to the technique, motion parameters of target are measured by algorithm based on differe...A novel frame shift and integral technique for the enhancement of low light level moving image sequence is introduced. According to the technique, motion parameters of target are measured by algorithm based on difference processing. To obtain spatial relativity, images are shifted according to the motion parameters. As a result, the processing of integral and average can be applied to images that have been shifted. The technique of frame shift and integral that includes the algorithm of motion parameter determination is discussed, experiments with low light level moving image sequences are also described. The experiment results show the effectiveness and the robustness of the parameter determination algorithm, and the improvement in the signal-to-noise ratio （SNR） of low light level moving images.展开更多
The low level red light irradiation dose that produced positive response on different cell indexes was selected through experiments.In fibroblast detection model,the low level red light irradiation dose that had posit...The low level red light irradiation dose that produced positive response on different cell indexes was selected through experiments.In fibroblast detection model,the low level red light irradiation dose that had positive response to the four indicators of mitochondrial membrane potential,ATP release,cell migration and collagen synthesis was screened.The experimental results showed that low level red light with a irradiation dose of 2 J/cm^(2) had a positive response to the above four indexes in fibroblast.The test model on fibroblast was later transferred to dermal papilla cells for further experimental verification.The results showed that low level red light with a irradiation dose of 2 J/cm^(2) also had a positive response to the four indicators of dermal papilla cells,namely,mitochondrial membrane potential,ATP release,cell proliferation rate and collagen synthesis.It is proved that the low level red light with a irradiation dose of 2 J/cm^(2) could improve the mitochondrial function,cell migration and collagen synthesis of fibroblast and dermal papilla cell,thus providing energy for cell activities,improving cell repair ability and cell anti-aging ability.展开更多
近年来,重复低强度红光疗法(repeated low-level red light therapy,RLRL)作为一种新兴的近视干预手段,在延缓眼轴增长和屈光度数加深方面展现出显著效果。大量临床研究证实其疗效优于阿托品及角膜塑形镜,然而其作用机制及长期安全性尚...近年来,重复低强度红光疗法(repeated low-level red light therapy,RLRL)作为一种新兴的近视干预手段,在延缓眼轴增长和屈光度数加深方面展现出显著效果。大量临床研究证实其疗效优于阿托品及角膜塑形镜,然而其作用机制及长期安全性尚不明确。基础研究表明RLRL可能通过利用纵向色差原理、调节视网膜多巴胺分泌、增加脉络膜厚度及血流灌注、改善巩膜缺氧、减轻炎症和氧化应激反应等多种途径控制近视进展。安全性方面,多数研究表明其短期安全性良好,但最新高分辨率成像研究提示潜在视网膜视锥细胞密度降低风险,且停用后存在反弹效应。本文对RLRL控制近视的作用机制、临床有效性和安全性进行综述,以期为临床应用提供参考。展开更多
A novel integrated circuit for driving LED lighting has been proposed, designed and fabricated. Besides the typical parts of LED driver, an integral part was added at the output terminal of error amplifier in the driv...A novel integrated circuit for driving LED lighting has been proposed, designed and fabricated. Besides the typical parts of LED driver, an integral part was added at the output terminal of error amplifier in the driver. In this way, a novel average current mode can be set up to take the place ordinary peak current control mode. In addition, a BUCK low-level topology was adopted, too. It can be used to drive up to eight 1 W HB LED lights with 350 mA constant current. In this way, the LED driver displays high performance, in which output current with less 1% error and total efficiency as high as 96%. The feasibility of the design has been verified by actual measurement on the fabricated chip.展开更多
使用范围综述的研究方法系统分析光生物调节疗法(photobiomodulation,PBM)在帕金森病(Parkinson disease,PD)患者中的临床应用,总结治疗方案、结局指标和疗效,为后续的临床研究和治疗提供参考。本文检索Web of Science、PubMed、Embase...使用范围综述的研究方法系统分析光生物调节疗法(photobiomodulation,PBM)在帕金森病(Parkinson disease,PD)患者中的临床应用,总结治疗方案、结局指标和疗效,为后续的临床研究和治疗提供参考。本文检索Web of Science、PubMed、Embase、Cochrane Library、中国知网和万方数据库,最终共纳入13项研究。结果发现PBM治疗能够有效改善PD患者的运动症状、非运动症状以及大脑结构,可以作为传统治疗的有益补充。但是大样本的随机对照试验研究仍然较少,选用的治疗参数也存在较大差异,因此还需要开展大规模、长时间的研究来进一步探究其疗效。展开更多
近视患病率逐年攀升,已成为全球性的重大公共卫生问题之一。目前的近视防控措施,如角膜塑形镜、离焦框架眼镜、软性离焦角膜接触镜、低浓度阿托品滴眼液均存在不足之处。重复低强度红光(RLRL)近年来成为儿童近视控制的手段之一。多项临...近视患病率逐年攀升,已成为全球性的重大公共卫生问题之一。目前的近视防控措施,如角膜塑形镜、离焦框架眼镜、软性离焦角膜接触镜、低浓度阿托品滴眼液均存在不足之处。重复低强度红光(RLRL)近年来成为儿童近视控制的手段之一。多项临床研究结果均表明,RLRL照射能够抑制儿童青少年近视的快速增长。近期一篇研究报告"Cone Density Changes After Repeated Low-Level Red Light Treatment in Children With Myopia"(《重复低强度红光治疗后近视儿童的视锥细胞密度变化》),在近视儿童的家长中引起了广泛讨论。本文详细分析此文章研究方法及结果,探讨是否能得出RLRL会影响近视儿童黄斑视锥细胞密度的结论。展开更多
电子轰击型有源像素传感器(Electron Bombarded Active Pixel Sensor,EBAPS)作为一种数字化微光成像器件,以其成像系统具有小型化、低成本和低功耗的优势,以及在昼夜条件下连续拍摄时具备清晰成像的能力,成为微光成像领域的研究热点。...电子轰击型有源像素传感器(Electron Bombarded Active Pixel Sensor,EBAPS)作为一种数字化微光成像器件,以其成像系统具有小型化、低成本和低功耗的优势,以及在昼夜条件下连续拍摄时具备清晰成像的能力,成为微光成像领域的研究热点。文章基于国产某型EBAPS微光器件,利用FPGA作为核心处理器,完成了EBAPS器件驱动电路、图像处理和跟踪电路、显示电路的设计。同时,构建了满足昼夜复用的光学系统,搭建了一种小型化的手持成像跟踪系统。实验结果表明,该EBAPS昼夜成像系统可在1×10^(-4)~1×10^(4) lx照度条件下实现良好的成像和跟踪效果。展开更多
文摘A mathematical model of quantum noise having much effect on the low light imaging system is set up. To simulate the quantum noise, the random numbers obeying noise distribution must be formed and are weighted on the basis of the model created. Three uniform random sequences are built by the linear congruential method, of which two are used to form integer number and decimal fraction parts of the new random sequence respectively and the third to shuffle the new sequence. And then a Gauss sequence is formed out of uniform distribution by a function transforming method. It actualizes the simulation in real time of quantum noise in the low light imaging system, where video flow is extracted in real time, the noise summed up and played back side by side with the original video signs by a simulation software.
文摘on the basis of analyzing the characteristics of low light level(LLL)image and ultra-violet image and the information amount of dual channel color night vision system,the LLL and ultra-violet color night vision technique is put forward.The methods of gray-scale modulation,frequency field fusion,special component fusion arc tried,and the improved LLL and ultra-violet image pseudo color fusion algorithms are presented.These new algorithms include subsection gray-scale modulation,image difference picking-up,component separation based on the reflected characteristics to night skylight reflection characteristics of objects and color space mapping which embodies the spectrum response of image sensor and nature vision.Some good results are obtained.
文摘A novel frame shift and integral technique for the enhancement of low light level moving image sequence is introduced. According to the technique, motion parameters of target are measured by algorithm based on difference processing. To obtain spatial relativity, images are shifted according to the motion parameters. As a result, the processing of integral and average can be applied to images that have been shifted. The technique of frame shift and integral that includes the algorithm of motion parameter determination is discussed, experiments with low light level moving image sequences are also described. The experiment results show the effectiveness and the robustness of the parameter determination algorithm, and the improvement in the signal-to-noise ratio （SNR） of low light level moving images.
文摘The low level red light irradiation dose that produced positive response on different cell indexes was selected through experiments.In fibroblast detection model,the low level red light irradiation dose that had positive response to the four indicators of mitochondrial membrane potential,ATP release,cell migration and collagen synthesis was screened.The experimental results showed that low level red light with a irradiation dose of 2 J/cm^(2) had a positive response to the above four indexes in fibroblast.The test model on fibroblast was later transferred to dermal papilla cells for further experimental verification.The results showed that low level red light with a irradiation dose of 2 J/cm^(2) also had a positive response to the four indicators of dermal papilla cells,namely,mitochondrial membrane potential,ATP release,cell proliferation rate and collagen synthesis.It is proved that the low level red light with a irradiation dose of 2 J/cm^(2) could improve the mitochondrial function,cell migration and collagen synthesis of fibroblast and dermal papilla cell,thus providing energy for cell activities,improving cell repair ability and cell anti-aging ability.
文摘近年来,重复低强度红光疗法(repeated low-level red light therapy,RLRL)作为一种新兴的近视干预手段,在延缓眼轴增长和屈光度数加深方面展现出显著效果。大量临床研究证实其疗效优于阿托品及角膜塑形镜,然而其作用机制及长期安全性尚不明确。基础研究表明RLRL可能通过利用纵向色差原理、调节视网膜多巴胺分泌、增加脉络膜厚度及血流灌注、改善巩膜缺氧、减轻炎症和氧化应激反应等多种途径控制近视进展。安全性方面,多数研究表明其短期安全性良好,但最新高分辨率成像研究提示潜在视网膜视锥细胞密度降低风险,且停用后存在反弹效应。本文对RLRL控制近视的作用机制、临床有效性和安全性进行综述,以期为临床应用提供参考。
文摘A novel integrated circuit for driving LED lighting has been proposed, designed and fabricated. Besides the typical parts of LED driver, an integral part was added at the output terminal of error amplifier in the driver. In this way, a novel average current mode can be set up to take the place ordinary peak current control mode. In addition, a BUCK low-level topology was adopted, too. It can be used to drive up to eight 1 W HB LED lights with 350 mA constant current. In this way, the LED driver displays high performance, in which output current with less 1% error and total efficiency as high as 96%. The feasibility of the design has been verified by actual measurement on the fabricated chip.
文摘使用范围综述的研究方法系统分析光生物调节疗法(photobiomodulation,PBM)在帕金森病(Parkinson disease,PD)患者中的临床应用,总结治疗方案、结局指标和疗效,为后续的临床研究和治疗提供参考。本文检索Web of Science、PubMed、Embase、Cochrane Library、中国知网和万方数据库,最终共纳入13项研究。结果发现PBM治疗能够有效改善PD患者的运动症状、非运动症状以及大脑结构,可以作为传统治疗的有益补充。但是大样本的随机对照试验研究仍然较少,选用的治疗参数也存在较大差异,因此还需要开展大规模、长时间的研究来进一步探究其疗效。
文摘近视患病率逐年攀升,已成为全球性的重大公共卫生问题之一。目前的近视防控措施,如角膜塑形镜、离焦框架眼镜、软性离焦角膜接触镜、低浓度阿托品滴眼液均存在不足之处。重复低强度红光(RLRL)近年来成为儿童近视控制的手段之一。多项临床研究结果均表明,RLRL照射能够抑制儿童青少年近视的快速增长。近期一篇研究报告"Cone Density Changes After Repeated Low-Level Red Light Treatment in Children With Myopia"(《重复低强度红光治疗后近视儿童的视锥细胞密度变化》),在近视儿童的家长中引起了广泛讨论。本文详细分析此文章研究方法及结果,探讨是否能得出RLRL会影响近视儿童黄斑视锥细胞密度的结论。
