The "Biofilms, Microbiomes and Oral Diseases: Challenges and Future Perspectives" symposium jointly organized by Penn Dental Medicine and West China School of Stomatology was held on 30 September 2017 at Pen...The "Biofilms, Microbiomes and Oral Diseases: Challenges and Future Perspectives" symposium jointly organized by Penn Dental Medicine and West China School of Stomatology was held on 30 September 2017 at Penn Wharton China Center(PWCC) in Beijing,China. The topics included the pathogenicity of oral biofilms, novel strategies for the control of biofilm-related diseases, oral microbiome and single-cell approaches, and the link between oral diseases and overall health. Researchers from a number of disciplines, representing institutions from China and Penn Dental Medicine, gathered to discuss advances in our understanding of biofilms, as well as future directions for the control of biofilm-related oral and systemic diseases.展开更多
1 Introduction The Great Salt Lake(GSL)is the defining hydrological feature of the Great Basin,North America’s largest desert--and it is the largest waterbody in the western USA.Despite the early(Eardley,1938)recogni...1 Introduction The Great Salt Lake(GSL)is the defining hydrological feature of the Great Basin,North America’s largest desert--and it is the largest waterbody in the western USA.Despite the early(Eardley,1938)recognition of"bioherms,"algal layers,and mats covering hundreds of square km of lake area,these features have not been the展开更多
Both populous and fast-growing, China and India share important similarities. Over the years, comparative studies on both countries, especially in terms of economic development, have become a hot topic around the worl...Both populous and fast-growing, China and India share important similarities. Over the years, comparative studies on both countries, especially in terms of economic development, have become a hot topic around the world. China and India issues have aroused intense attention and interest in international academia. Three articles in this issue examine the race between the dragon and the elephant in the arena of economic development, information industry and software. In his article "A closer look at Chinese and Indian economic development," Prof. Huang Qunhui compares China and India’s economic development from national strategic perspectives based on his first-hand research; in "What China and India can learn from each other in the information industry?" Prof. Shen Kaiyan undertakes a comparative analysis of the development of information industries in China and India; lastly, Prof.Fang Hong’s empirical study looks at competition and cooperation in the Chinese and Indian software industries. This selection of essays begins with overall economic development, moves to a closer examination of the information industry, and then concludes with a look at the software industry, giving us an extremely broad yet also detailed comparison of the economies of these two emerging giants.展开更多
An overview of carbon emissions tradingin China and in the world ●With fast development of CDM, the global carbon mar-ket was doubled in 2007 compared with that in 2006.●China’s volume of certified emission reducti...An overview of carbon emissions tradingin China and in the world ●With fast development of CDM, the global carbon mar-ket was doubled in 2007 compared with that in 2006.●China’s volume of certified emission reductions (CERs)trading and expected annual emission reductions top the world.Xie Fei:Climate change and energy supply has become one of展开更多
■The world’s most prestigious art shows teamed up in Europe this spring to create a European art tour that offered an unparalleled opportunity to examine contemporary art from around the world.It was an endless expe...■The world’s most prestigious art shows teamed up in Europe this spring to create a European art tour that offered an unparalleled opportunity to examine contemporary art from around the world.It was an endless experience of展开更多
1. The Role of Human Rights Education in Promoting Human Rights Development 1. Human rights education shapes the soft environment for human rights development
Peter is in his room. He is sitting on the floor. He is fixing (修理) his tape recorder(磁带录音机). His radio is on. He's listening to music. But look at Peter's room. What a mess (混乱)! His cassettes (盒式...Peter is in his room. He is sitting on the floor. He is fixing (修理) his tape recorder(磁带录音机). His radio is on. He's listening to music. But look at Peter's room. What a mess (混乱)! His cassettes (盒式磁带) are lying all over the room. Two cassettes are on the table. Three are under the table. A big recorder is on展开更多
The Pacific island nation of Nauru used to be a beautiful place.Now it is an ecological disaster area.Nauru’s heartbreaking story could have one good consequence-other countries might learn from its mistakes.For thou...The Pacific island nation of Nauru used to be a beautiful place.Now it is an ecological disaster area.Nauru’s heartbreaking story could have one good consequence-other countries might learn from its mistakes.For thousands of years,Polynesian people lived in the remote island of Nauru,far from western civilization.The first European to arrive was John Fearn in 1798.He was the British captain of the Hunter,a whaling ship.He called the island Pleasant Island.展开更多
教学内容：三年级下学期,第三单元第一课时课前准备：挂图、多媒体、单词卡片、磁带教学设计思路：从学生的学习兴趣出发,用新颖的教学方法让学生喜欢英语课,通过互动游戏,用英语向大家介绍自己的五官,从而让学生非常轻松的融入英语课堂...教学内容：三年级下学期,第三单元第一课时课前准备：挂图、多媒体、单词卡片、磁带教学设计思路：从学生的学习兴趣出发,用新颖的教学方法让学生喜欢英语课,通过互动游戏,用英语向大家介绍自己的五官,从而让学生非常轻松的融入英语课堂.教学目标：1.学生们能说出新单词nose,eye,big,small.句型hello!Look at my nose.Wow!It＇s big! Touch your nose!2.启发学生拓展更多词汇去思考问题,想想身体其他部位的单词怎样去表达,感受语言的奥妙.3.记住形容词和名词的出现顺序,感受英语中对应词的出现.展开更多
Look at Me,’stories of two"Charlotte"s who are searching for their true self.In this fiction,Egan adopts alternative narratives between first-person narrative and third-person narrative to tell the stories ...Look at Me,’stories of two"Charlotte"s who are searching for their true self.In this fiction,Egan adopts alternative narratives between first-person narrative and third-person narrative to tell the stories of characters.In the process of first-person narrative,Egan uses unreliable first-person narrative to tell the story of the main protagonist.This fiction deals with the issues around image culture in depth.It demonstrates eloquently how often fiction,in its visionary form,speaks of truth.展开更多
Artificial intelligence(AI)was a hot topic at this year’s annual meetings of the National People’s Congress and the National Committee of the Chinese People’s Political Consultative Conference,also referred to as t...Artificial intelligence(AI)was a hot topic at this year’s annual meetings of the National People’s Congress and the National Committee of the Chinese People’s Political Consultative Conference,also referred to as the Two Sessions.The recently released AI chatbot DeepSeek has quickly gained global attention and users with its rich features.展开更多
AIM:To construct an intelligent segmentation scheme for precise localization of central serous chorioretinopathy(CSC)leakage points,thereby enabling ophthalmologists to deliver accurate laser treatment without navigat...AIM:To construct an intelligent segmentation scheme for precise localization of central serous chorioretinopathy(CSC)leakage points,thereby enabling ophthalmologists to deliver accurate laser treatment without navigational laser equipment.METHODS:A dataset with dual labels(point-level and pixel-level)was first established based on fundus fluorescein angiography(FFA)images of CSC and subsequently divided into training(102 images),validation(40 images),and test(40 images)datasets.An intelligent segmentation method was then developed,based on the You Only Look Once version 8 Pose Estimation(YOLOv8-Pose)model and segment anything model(SAM),to segment CSC leakage points.Next,the YOLOv8-Pose model was trained for 200 epochs,and the best-performing model was selected to form the optimal combination with SAM.Additionally,the classic five types of U-Net series models[i.e.,U-Net,recurrent residual U-Net(R2U-Net),attention U-Net(AttU-Net),recurrent residual attention U-Net(R2AttUNet),and nested U-Net(UNet^(++))]were initialized with three random seeds and trained for 200 epochs,resulting in a total of 15 baseline models for comparison.Finally,based on the metrics including Dice similarity coefficient(DICE),intersection over union(IoU),precision,recall,precisionrecall(PR)curve,and receiver operating characteristic(ROC)curve,the proposed method was compared with baseline models through quantitative and qualitative experiments for leakage point segmentation,thereby demonstrating its effectiveness.RESULTS:With the increase of training epochs,the mAP50-95,Recall,and precision of the YOLOv8-Pose model showed a significant increase and tended to stabilize,and it achieved a preliminary localization success rate of 90%(i.e.,36 images)for CSC leakage points in 40 test images.Using manually expert-annotated pixel-level labels as the ground truth,the proposed method achieved outcomes with a DICE of 57.13%,an IoU of 45.31%,a precision of 45.91%,a recall of 93.57%,an area under the PR curve(AUC-PR)of 0.78 and an area under the ROC curve(AUC-ROC)of 0.97,which enables more accurate segmentation of CSC leakage points.CONCLUSION:By combining the precise localization capability of the YOLOv8-Pose model with the robust and flexible segmentation ability of SAM,the proposed method not only demonstrates the effectiveness of the YOLOv8-Pose model in detecting keypoint coordinates of CSC leakage points from the perspective of application innovation but also establishes a novel approach for accurate segmentation of CSC leakage points through the“detect-then-segment”strategy,thereby providing a potential auxiliary means for the automatic and precise realtime localization of leakage points during traditional laser photocoagulation for CSC.展开更多
基金in part made possible through Penn Global Education Fund
文摘The "Biofilms, Microbiomes and Oral Diseases: Challenges and Future Perspectives" symposium jointly organized by Penn Dental Medicine and West China School of Stomatology was held on 30 September 2017 at Penn Wharton China Center(PWCC) in Beijing,China. The topics included the pathogenicity of oral biofilms, novel strategies for the control of biofilm-related diseases, oral microbiome and single-cell approaches, and the link between oral diseases and overall health. Researchers from a number of disciplines, representing institutions from China and Penn Dental Medicine, gathered to discuss advances in our understanding of biofilms, as well as future directions for the control of biofilm-related oral and systemic diseases.
文摘1 Introduction The Great Salt Lake(GSL)is the defining hydrological feature of the Great Basin,North America’s largest desert--and it is the largest waterbody in the western USA.Despite the early(Eardley,1938)recognition of"bioherms,"algal layers,and mats covering hundreds of square km of lake area,these features have not been the
文摘Both populous and fast-growing, China and India share important similarities. Over the years, comparative studies on both countries, especially in terms of economic development, have become a hot topic around the world. China and India issues have aroused intense attention and interest in international academia. Three articles in this issue examine the race between the dragon and the elephant in the arena of economic development, information industry and software. In his article "A closer look at Chinese and Indian economic development," Prof. Huang Qunhui compares China and India’s economic development from national strategic perspectives based on his first-hand research; in "What China and India can learn from each other in the information industry?" Prof. Shen Kaiyan undertakes a comparative analysis of the development of information industries in China and India; lastly, Prof.Fang Hong’s empirical study looks at competition and cooperation in the Chinese and Indian software industries. This selection of essays begins with overall economic development, moves to a closer examination of the information industry, and then concludes with a look at the software industry, giving us an extremely broad yet also detailed comparison of the economies of these two emerging giants.
文摘An overview of carbon emissions tradingin China and in the world ●With fast development of CDM, the global carbon mar-ket was doubled in 2007 compared with that in 2006.●China’s volume of certified emission reductions (CERs)trading and expected annual emission reductions top the world.Xie Fei:Climate change and energy supply has become one of
文摘■The world’s most prestigious art shows teamed up in Europe this spring to create a European art tour that offered an unparalleled opportunity to examine contemporary art from around the world.It was an endless experience of
文摘1. The Role of Human Rights Education in Promoting Human Rights Development 1. Human rights education shapes the soft environment for human rights development
文摘Peter is in his room. He is sitting on the floor. He is fixing (修理) his tape recorder(磁带录音机). His radio is on. He's listening to music. But look at Peter's room. What a mess (混乱)! His cassettes (盒式磁带) are lying all over the room. Two cassettes are on the table. Three are under the table. A big recorder is on
文摘The Pacific island nation of Nauru used to be a beautiful place.Now it is an ecological disaster area.Nauru’s heartbreaking story could have one good consequence-other countries might learn from its mistakes.For thousands of years,Polynesian people lived in the remote island of Nauru,far from western civilization.The first European to arrive was John Fearn in 1798.He was the British captain of the Hunter,a whaling ship.He called the island Pleasant Island.
文摘教学内容：三年级下学期,第三单元第一课时课前准备：挂图、多媒体、单词卡片、磁带教学设计思路：从学生的学习兴趣出发,用新颖的教学方法让学生喜欢英语课,通过互动游戏,用英语向大家介绍自己的五官,从而让学生非常轻松的融入英语课堂.教学目标：1.学生们能说出新单词nose,eye,big,small.句型hello!Look at my nose.Wow!It＇s big! Touch your nose!2.启发学生拓展更多词汇去思考问题,想想身体其他部位的单词怎样去表达,感受语言的奥妙.3.记住形容词和名词的出现顺序,感受英语中对应词的出现.
文摘Look at Me,’stories of two"Charlotte"s who are searching for their true self.In this fiction,Egan adopts alternative narratives between first-person narrative and third-person narrative to tell the stories of characters.In the process of first-person narrative,Egan uses unreliable first-person narrative to tell the story of the main protagonist.This fiction deals with the issues around image culture in depth.It demonstrates eloquently how often fiction,in its visionary form,speaks of truth.
文摘Artificial intelligence(AI)was a hot topic at this year’s annual meetings of the National People’s Congress and the National Committee of the Chinese People’s Political Consultative Conference,also referred to as the Two Sessions.The recently released AI chatbot DeepSeek has quickly gained global attention and users with its rich features.
基金Supported by the Shenzhen Science and Technology Program(No.JCYJ20240813152704006)the National Natural Science Foundation of China(No.62401259)+2 种基金the Fundamental Research Funds for the Central Universities(No.NZ2024036)the Postdoctoral Fellowship Program of CPSF(No.GZC20242228)High Performance Computing Platform of Nanjing University of Aeronautics and Astronautics。
文摘AIM:To construct an intelligent segmentation scheme for precise localization of central serous chorioretinopathy(CSC)leakage points,thereby enabling ophthalmologists to deliver accurate laser treatment without navigational laser equipment.METHODS:A dataset with dual labels(point-level and pixel-level)was first established based on fundus fluorescein angiography(FFA)images of CSC and subsequently divided into training(102 images),validation(40 images),and test(40 images)datasets.An intelligent segmentation method was then developed,based on the You Only Look Once version 8 Pose Estimation(YOLOv8-Pose)model and segment anything model(SAM),to segment CSC leakage points.Next,the YOLOv8-Pose model was trained for 200 epochs,and the best-performing model was selected to form the optimal combination with SAM.Additionally,the classic five types of U-Net series models[i.e.,U-Net,recurrent residual U-Net(R2U-Net),attention U-Net(AttU-Net),recurrent residual attention U-Net(R2AttUNet),and nested U-Net(UNet^(++))]were initialized with three random seeds and trained for 200 epochs,resulting in a total of 15 baseline models for comparison.Finally,based on the metrics including Dice similarity coefficient(DICE),intersection over union(IoU),precision,recall,precisionrecall(PR)curve,and receiver operating characteristic(ROC)curve,the proposed method was compared with baseline models through quantitative and qualitative experiments for leakage point segmentation,thereby demonstrating its effectiveness.RESULTS:With the increase of training epochs,the mAP50-95,Recall,and precision of the YOLOv8-Pose model showed a significant increase and tended to stabilize,and it achieved a preliminary localization success rate of 90%(i.e.,36 images)for CSC leakage points in 40 test images.Using manually expert-annotated pixel-level labels as the ground truth,the proposed method achieved outcomes with a DICE of 57.13%,an IoU of 45.31%,a precision of 45.91%,a recall of 93.57%,an area under the PR curve(AUC-PR)of 0.78 and an area under the ROC curve(AUC-ROC)of 0.97,which enables more accurate segmentation of CSC leakage points.CONCLUSION:By combining the precise localization capability of the YOLOv8-Pose model with the robust and flexible segmentation ability of SAM,the proposed method not only demonstrates the effectiveness of the YOLOv8-Pose model in detecting keypoint coordinates of CSC leakage points from the perspective of application innovation but also establishes a novel approach for accurate segmentation of CSC leakage points through the“detect-then-segment”strategy,thereby providing a potential auxiliary means for the automatic and precise realtime localization of leakage points during traditional laser photocoagulation for CSC.
