An all-solid-state ion-selective electrode(ISE)for the detection of potassium ions in complex media was developed based on functional peptides with both antibacterial and antifouling properties.While exhibiting unique...An all-solid-state ion-selective electrode(ISE)for the detection of potassium ions in complex media was developed based on functional peptides with both antibacterial and antifouling properties.While exhibiting unique antifouling property,the ISE capitalized on the high surface area of the conductive metalorganic framework(MOF)solid transducer layer to facilitate rapid ion-electron transfer,consequently improving the electrode stability.For a short period,the application of a±1 n A current to the ISE resulted in a slight potential drift of 2.5μV/s,while for a long-term stability test,the ISE maintained a stable Nernstian response slope over 8 days.The antifouling and antibacterial peptide effectively eradicated bacteria from the electrode surface while inhibited the adhesion of bacteria and other biological organisms.Both theoretical calculations and experimental results indicated that the incorporation of peptides in the sensing membrane did not compromise the detection performance of the ISE.The prepared antifouling potassium ion-selective electrode exhibited a Nernstian response range spanning from 1.0×10^(–8)mol/L to 1.0×10–3mol/L,with a detection limit of 2.51 nmol/L.Crucially,the prepared solid-contact ISE maintained excellent antifouling and sensing capabilities in actual seawater and human urine,indicating a promising feasibility of this strategy for constructing ISEs suitable for practical application in complex systems.展开更多
基金supported by the National Natural Science Foundation of China(Nos.22174082,22374085)the Key Research and Development Program of Shandong Province(No.2021ZDSYS30)Qingdao Postdoctoral Innovation Project Funding(No.QDBSH20220201038)。
文摘An all-solid-state ion-selective electrode(ISE)for the detection of potassium ions in complex media was developed based on functional peptides with both antibacterial and antifouling properties.While exhibiting unique antifouling property,the ISE capitalized on the high surface area of the conductive metalorganic framework(MOF)solid transducer layer to facilitate rapid ion-electron transfer,consequently improving the electrode stability.For a short period,the application of a±1 n A current to the ISE resulted in a slight potential drift of 2.5μV/s,while for a long-term stability test,the ISE maintained a stable Nernstian response slope over 8 days.The antifouling and antibacterial peptide effectively eradicated bacteria from the electrode surface while inhibited the adhesion of bacteria and other biological organisms.Both theoretical calculations and experimental results indicated that the incorporation of peptides in the sensing membrane did not compromise the detection performance of the ISE.The prepared antifouling potassium ion-selective electrode exhibited a Nernstian response range spanning from 1.0×10^(–8)mol/L to 1.0×10–3mol/L,with a detection limit of 2.51 nmol/L.Crucially,the prepared solid-contact ISE maintained excellent antifouling and sensing capabilities in actual seawater and human urine,indicating a promising feasibility of this strategy for constructing ISEs suitable for practical application in complex systems.
