Bigeye tuna is a protein-rich fish that is susceptible to spoilage during cold storage,however,there is limited information on untargeted metabolomic profiling of bigeye tuna concerning spoilage-associated enzymes and...Bigeye tuna is a protein-rich fish that is susceptible to spoilage during cold storage,however,there is limited information on untargeted metabolomic profiling of bigeye tuna concerning spoilage-associated enzymes and metabolites.This study aimed to investigate how cold storage affects enzyme activities,nutrient composition,tissue microstructures and spoilage metabolites of bigeye tuna.The activities of cathepsins B,H,L increased,while Na^(+)/K^(+)-ATPase and Mg^(2+)-ATPase decreased,α-glucosidase,lipase and lipoxygenase first increased and then decreased during cold storage,suggesting that proteins undergo degradation and ATP metabolism occurs at a faster rate during cold storage.Nutrient composition(moisture and lipid content),total amino acids decreased,suggesting that the nutritional value of bigeye tuna was reduced.Besides,a logistic regression equation has been established as a food analysis tool and assesses the dynamics and correlation of the enzyme of bigeye tuna during cold storage.Based on untargeted metabolomic profiling analysis,a total of 524 metabolites were identified in the bigeye tuna contained several spoilage metabolites involved in lipid metabolism(glycerophosphocholine and choline phosphate),amino acid metabolism(L-histidine,5-deoxy-5′-(methylthio)adenosine,5-methylthioadenosine),carbohydrate metabolism(D-gluconic acid,α-D-fructose 1,6-bisphosphate,D-glyceraldehyde 3-phosphate).The results of tissue microstructures of tuna showed a looser network and visible deterioration of tissue fiber during cold storage.Therefore,metabolomic analysis and tissue microstructures provide insight into the spoilage mechanism investigations on bigeye tuna during cold storage.展开更多
Internal solitary wave propagation over a submarine ridge results in energy dissipation, in which the hydrodynamic interaction between a wave and ridge affects marine environment. This study analyzes the effects of ri...Internal solitary wave propagation over a submarine ridge results in energy dissipation, in which the hydrodynamic interaction between a wave and ridge affects marine environment. This study analyzes the effects of ridge height and potential energy during wave-ridge interaction with a binary and cumulative logistic regression model. In testing the Global Null Hypothesis, all values are p 〈0.001, with three statistical methods, such as Likelihood Ratio, Score, and Wald. While comparing with two kinds of models, tests values obtained by cumulative logistic regression models are better than those by binary logistic regression models. Although this study employed cumulative logistic regression model, three probability functions p^1, p^2 and p^3, are utilized for investigating the weighted influence of factors on wave reflection. Deviance and Pearson tests are applied to cheek the goodness-of-fit of the proposed model. The analytical results demonstrated that both ridge height （X1 ） and potential energy （X2 ） significantly impact （p 〈 0. 0001 ） the amplitude-based refleeted rate; the P-values for the deviance and Pearson are all 〉 0.05 （0.2839, 0.3438, respectively）. That is, the goodness-of-fit between ridge height （ X1 ） and potential energy （X2） can further predict parameters under the scenario of the best parsimonious model. Investigation of 6 predictive powers （ R2, Max-rescaled R^2, Sorners＇ D, Gamma, Tau-a, and c, respectively） indicate that these predictive estimates of the proposed model have better predictive ability than ridge height alone, and are very similar to the interaction of ridge height and potential energy. It can be concluded that the goodness-of-fit and prediction ability of the cumulative logistic regression model are better than that of the binary logistic regression model.展开更多
With the well-being trends to pursue a healthy life, mountain ginseng(Panax ginseng) is rising as one of the most profitable forest products in South Korea. This study was aimed at evaluating a new methodology for ide...With the well-being trends to pursue a healthy life, mountain ginseng(Panax ginseng) is rising as one of the most profitable forest products in South Korea. This study was aimed at evaluating a new methodology for identifying suitable sites for mountain ginseng cultivation in the country. Forest vegetation data were collected from 46 sites and the spatial distribution of all sites was analyzed using GIS data for topographic position, landform, solar radiation, and topographic wetness. The physical and chemical properties of the soil samples, including moisture content, p H, organic matter, total nitrogen, exchangeable cations, available phosphorous, and soil texture, were analyzed. The cultivation suitability at each site was assessed based on the environmental conditions using logistic regression(LR) and geographically weighted logistic regression(GWLR) and the results of both methods were compared. The results show that the areas with northern aspect and higher levels of solar radiation, moisture content, total nitrogen, and sand ratio are more likely to be identified as suitable sites for ginseng cultivation. In contrast to the LR, the spatial modeling with the GWLR results in an increase in the model fitness and indicates that a significant portion of spatialautocorrelation in the data decreases. A higher value of the area under the receiver operating characteristic(ROC) curve presents a better prediction accuracy of site suitability by the GWLR. The geographically weighted coefficient estimates of the model are nonstationary, and reveal that different site suitability is associated with the geographical location of the forest stands. The GWLR increases the accuracy of selecting suitable sites by considering the geographical variations in the characteristics of the cultivation sites.展开更多
Road traffic crashes are becoming thorny issues being faced worldwide.Traffic crashes are spatiotemporal events and the research on the spatiotemporal patterns and variation trends of traffic crashes has been carried ...Road traffic crashes are becoming thorny issues being faced worldwide.Traffic crashes are spatiotemporal events and the research on the spatiotemporal patterns and variation trends of traffic crashes has been carried out.However,the impact of built environment on traffic crash spatiotemporal trends has not received much attention.Moreover,the spatial non-stationarity between the variation trends of traffic crashes and their influencing factors is usually neglected.To make up for the lack of analysis of built environment factors influencing spatiotemporal hotspot trends in traffic crashes,this paper proposed a method of“ST-GWLR”for analyzing the influence of built environment factors on spatiotemporal hotspot trends of traffic crashes by combining the spatiotemporal hotspot trend analysis and Geographically Weighted Logistic Regression(GWLR)modeling methods.Firstly,the traffic crash spatiotemporal hotspot trends were explored using the space-time cube model,hotspot analysis,and Mann-Kendall trend test.Then,the GWLR was introduced to capture the spatial non-stationarity neglected by the classic Global Logistic Regression(GLR)model,to improve the accuracy of the model estimation.GWLR model is used for the first time to analyze the significant local correlation between the traffic crash spatiotemporal hotspot trends and the built environment factors,to accurately and effectively identify the built environment factors that have significant influences on the hotspot trends of traffic crashes.The performance of the GWLR models and GLR models was examined and compared sufficiently.The results showed that the proposed ST-GWLR,which captured spatial non-stationarity,performed better than the classic GLR combined with spatiotemporal analysis,and improved the prediction accuracy of the models by 14.9%,13.9%,and 15.1%,respectively.There were significant local correlations between intensifying hotspots and persistent hotspots of traffic crashes and the built environment factors.The findings of this paper have positive implications for traffic safety management and urban built environment planning.展开更多
Bailongjiang watershed in southern Gansu province, China, is one of the most landslide-prone regions in China, characterized by very high frequency of landslide occurrence. In order to predict the landslide occurrence...Bailongjiang watershed in southern Gansu province, China, is one of the most landslide-prone regions in China, characterized by very high frequency of landslide occurrence. In order to predict the landslide occurrence, a comprehensive map of landslide susceptibility is required which may be significantly helpful in reducing loss of property and human life. In this study, an integrated model of information value method and logistic regression is proposed by using their merits at maximum and overcoming their weaknesses, which may enhance precision and accuracy of landslide susceptibility assessment. A detailed and reliable landslide inventory with 1587 landslides was prepared and randomly divided into two groups,(i) training dataset and(ii) testing dataset. Eight distinct landslide conditioning factors including lithology, slope gradient, aspect, elevation, distance to drainages,distance to faults, distance to roads and vegetation coverage were selected for landslide susceptibility mapping. The produced landslide susceptibility maps were validated by the success rate and prediction rate curves. The validation results show that the success rate and the prediction rate of the integrated model are 81.7 % and 84.6 %, respectively, which indicate that the proposed integrated method is reliable to produce an accurate landslide susceptibility map and the results may be used for landslides management and mitigation.展开更多
The Wenchuan earthquake on May 12,2008 caused numerous collapses,landslides,barrier lakes,and debris flows.Landslide susceptibility mapping is important for evaluation of environmental capacity and also as a guide for...The Wenchuan earthquake on May 12,2008 caused numerous collapses,landslides,barrier lakes,and debris flows.Landslide susceptibility mapping is important for evaluation of environmental capacity and also as a guide for post-earthquake reconstruction.In this paper,a logistic regression model was developed within the framework of GIS to map landslide susceptibility.Qingchuan County,a heavily affected area,was selected for the study.Distribution of landslides was prepared by interpretation of multi-temporal and multi-resolution remote sensing images(ADS40 aerial imagery,SPOT5 imagery and TM imagery,etc.) and field surveys.The Certainly Factor method was used to find the influencial factors,indicating that lithologic groups,distance from major faults,slope angle,profile curvature,and altitude are the dominant factors influencing landslides.The weight of each factor was determined using a binomial logistic regression model.Landslide susceptibility mapping was based on spatial overlay analysis and divided into five classes.Major faults have the most significant impact,and landslides will occur most likely in areas near the faults.Onethird of the area has a high or very high susceptibility,located in the northeast,south and southwest,including 65.3% of all landslides coincident with the earthquake.The susceptibility map can reveal the likelihood of future failures,and it will be useful for planners during the rebuilding process and for future zoning issues.展开更多
Landslide susceptibility map is one of the study fields portraying the spatial distribution of future slope failure sus- ceptibility. This paper deals with past methods for producing landslide susceptibility map and d...Landslide susceptibility map is one of the study fields portraying the spatial distribution of future slope failure sus- ceptibility. This paper deals with past methods for producing landslide susceptibility map and divides these methods into 3 types. The logistic linear regression approach is further elaborated on by crosstabs method, which is used to analyze the relationship between the categorical or binary response variable and one or more continuous or categorical or binary explanatory variables derived from samples. It is an objective assignment of coefficients serving as weights of various factors under considerations while expert opinions make great difference in heuristic approaches. Different from deterministic approach, it is very applicable to regional scale. In this study, double logistic regression is applied in the study area. The entire study area is first analyzed. The logistic regression equation showed that elevation, proximity to road, river and residential area are main factors triggering land- slide occurrence in this area. The prediction accuracy of the first landslide susceptibility map was showed to be 80%. Along the road and residential area, almost all areas are in high landslide susceptibility zone. Some non-landslide areas are incorrectly divided into high and medium landslide susceptibility zone. In order to improve the status, a second logistic regression was done in high landslide susceptibility zone using landslide cells and non-landslide sample cells in this area. In the second logistic regression analysis, only engineering and geological conditions are important in these areas and are entered in the new logistic regression equation indicating that only areas with unstable engineering and geological conditions are prone to landslide during large scale engineering activity. Taking these two logistic regression results into account yields a new landslide susceptibility map. Double logistic regression analysis improved the non-landslide prediction accuracy. During calculation of parameters for logistic regres- sion, landslide density is used to transform nominal variable to numeric variable and this avoids the creation of an excessively high number of dummy variables.展开更多
Landslide susceptibility mapping is the first step in regional hazard management as it helps to understand the spatial distribution of the probability of slope failure in an area.An attempt is made to map the landslid...Landslide susceptibility mapping is the first step in regional hazard management as it helps to understand the spatial distribution of the probability of slope failure in an area.An attempt is made to map the landslide susceptibility in Tevankarai Ar subwatershed,Kodaikkanal,India using binary logistic regression analysis.Geographic Information System is used to prepare the database of the predictor variables and landslide inventory map,which is used to build the spatial model of landslide susceptibility.The model describes the relationship between the dependent variable(presence and absence of landslide) and the independent variables selected for study(predictor variables) by the best fitting function.A forward stepwise logistic regression model using maximum likelihood estimation is used in the regression analysis.An inventory of 84 landslides and cells within a buffer distance of 10m around the landslide is used as the dependent variable.Relief,slope,aspect,plan curvature,profile curvature,land use,soil,topographic wetness index,proximity to roads and proximity to lineaments are taken as independent variables.The constant and the coefficient of the predictor variable retained by the regression model are used to calculate the probability of slope failure and analyze the effect of each predictor variable on landslide occurrence in thestudy area.The model shows that the most significant parameter contributing to landslides is slope.The other significant parameters are profile curvature,soil,road,wetness index and relief.The predictive logistic regression model is validated using temporal validation data-set of known landslide locations and shows an accuracy of 85.29 %.展开更多
A detailed landslide susceptibility map was produced in the Youfang catchment using logistic regression method with datasets developed for a geographic information system(GIS).Known as one of the most landslide-prone ...A detailed landslide susceptibility map was produced in the Youfang catchment using logistic regression method with datasets developed for a geographic information system(GIS).Known as one of the most landslide-prone areas in China, the Youfang catchment of Longnan mountain region,which lies in the transitional area among QinghaiTibet Plateau, loess Plateau and Sichuan Basin, was selected as a representative case to evaluate the frequency and distribution of landslides.Statistical relationships for landslide susceptibility assessment were developed using landslide and landslide causative factor databases.Logistic regression(LR)was used to create the landslide susceptibility maps based on a series of available data sources: landslide inventory; distance to drainage systems, faults and roads; slope angle and aspect; topographic elevation and topographical wetness index, and land use.The quality of the landslide susceptibility map produced in this paper was validated and the result can be used fordesigning protective and mitigation measures against landslide hazards.The landslide susceptibility map is expected to provide a fundamental tool for landslide hazards assessment and risk management in the Youfang catchment.展开更多
Landslide distribution and susceptibility mapping are the fundamental steps for landslide-related hazard and disaster risk management activities, especially in the Himalaya region which has resulted in a great deal of...Landslide distribution and susceptibility mapping are the fundamental steps for landslide-related hazard and disaster risk management activities, especially in the Himalaya region which has resulted in a great deal of death and damage to property. To better understand the landslide condition in the Nepal Himalaya, we carried out an investigation on the landslide distribution and susceptibility using the landslide inventory data and 12 different contributing factors in the Dailekh district, Western Nepal. Based on the evaluation of the frequency distribution of the landslide, the relationship between the landslide and the various contributing factors was determined.Then, the landslide susceptibility was calculated using logistic regression and statistical index methods along with different topographic(slope, aspect, relative relief, plan curvature, altitude, topographic wetness index) and non-topographic factors(distance from river, normalized difference vegetation index(NDVI), distance from road, precipitation, land use and land cover, and geology), and 470(70%) of total 658 landslides. The receiver operating characteristic(ROC) curve analysis using 198(30%) of total landslides showed that the prediction curve rates(area under the curve, AUC) values for two methods(logistic regression and statistical index) were 0.826, and 0.823with success rates of 0.793, and 0.811, respectively. The values of R-Index for the logistic regression and statistical index methods were83.66 and 88.54, respectively, consisting of high susceptible hazard classes. In general, this research concluded that the cohesive and coherent natural interplay of topographic and non-topographic factors strongly affects landslide occurrence, distribution, and susceptibility condition in the Nepal Himalaya region. Furthermore, the reliability of these two methods is verified for landslide susceptibility mapping in Nepal’s central mountain region.展开更多
This study aimed to assess the potential of in-situ measured soil and vegetation characteristics in landslide susceptibility analyses.First,data for eight independent variables,i.e.,soil moisture content,soil organic ...This study aimed to assess the potential of in-situ measured soil and vegetation characteristics in landslide susceptibility analyses.First,data for eight independent variables,i.e.,soil moisture content,soil organic content,compaction of soil(soil toughness),plant root strength,crop biomass,tree diameter at knee height,Shannon Wiener Index(SWI)for trees and herbs was assembled from field tests at two historic landslide locations:Aranayaka and Kurukudegama,Sri Lanka.An economical,finer resolution database was obtained as the field tests were not cost-prohibitive.The logistic regression(LR)analysis showed that soil moisture content,compaction of soil,SWI for trees and herbs were statistically significant at P<0.05.The variance inflation factors(VIFs)were computed to test for multicollinearity.VIF values(<2)confirmed the absence of multicollinearity between four independent variables in the LR model.Receiver Operating Characteristics(ROC)curve and Confusion Metrix(CM)methods were used to validate the model.In ROC analysis,areas under the curve of Success Rate Curve and Prediction Rate Curve were 84.5% and 96.6%,respectively,demonstrating the model’s excellent compatibility and predictability.According to the CM,the model demonstrated a 79.6% accuracy,63.6% precision,100% recall,and a F-measure of 77.8%.The model coefficients revealed that the vegetation cover has a more significant contribution to landslide susceptibility than soil characteristics.Finally,the susceptibility map,which was then classified as low,medium,and highly susceptible areas based on the natural breaks(Jenks)method,was generated using geographical information systems(GIS)techniques.All the historic landslide locations fell into the high susceptibility areas.Thus,validation of the model and inspection of the susceptibility map indicated that the in-situ soil and vegetation characteristics used in the model could be employed to demarcate historical landslide patches and identify landslide susceptible locations with high confidence.展开更多
The currently prevalent machine performance degradation assessment techniques involve estimating a machine＇s current condition based upon the recognition of indications of failure features,which entail complete data ...The currently prevalent machine performance degradation assessment techniques involve estimating a machine＇s current condition based upon the recognition of indications of failure features,which entail complete data collected in different conditions.However,failure data are always hard to acquire,thus making those techniques hard to be applied.In this paper,a novel method which does not need failure history data is introduced.Wavelet packet decomposition（WPD） is used to extract features from raw signals,principal component analysis（PCA） is utilized to reduce feature dimensions,and Gaussian mixture model（GMM） is then applied to approximate the feature space distributions.Single-channel confidence value（SCV） is calculated by the overlap between GMM of the monitoring condition and that of the normal condition,which can indicate the performance of single-channel.Furthermore,multi-channel confidence value（MCV）,which can be deemed as the overall performance index of multi-channel,is calculated via logistic regression（LR） and that the task of decision-level sensor fusion is also completed.Both SCV and MCV can serve as the basis on which proactive maintenance measures can be taken,thus preventing machine breakdown.The method has been adopted to assess the performance of the turbine of a centrifugal compressor in a factory of Petro-China,and the result shows that it can effectively complete this task.The proposed method has engineering significance for machine performance degradation assessment.展开更多
This paper proposed a new method for quantitative assessment of visual detectability of damage based on logistic regression,using the Probability of Detection(POD)as a criterion.Experiments were performed to establish...This paper proposed a new method for quantitative assessment of visual detectability of damage based on logistic regression,using the Probability of Detection(POD)as a criterion.Experiments were performed to establish the massive hit/miss data of visual inspection.Authoritative investigations verified the reliability of the data.The prediction function concluded comprises more than one flaw size parameters,including the depth and diameter of the dents.The results show that the depth and diameter of the dents are pivotal for the evaluation of detectability;the type of detection,the detection distance,and the qualifications of personnel are critical external factors to be considered.This function,with an accuracy rate of nearly 85%,is capable of predicting the visual detection probability of impact damage under various detection environments,which will provide a reference for the damage tolerance design of composite materials and field maintenance in the NonDestructive Testing(NDT)field.展开更多
Ecological land is an important guarantee to maintain urban ecological security and sustainable development.Although increasing studies have been brought to ecological land,with few explorations of the relative import...Ecological land is an important guarantee to maintain urban ecological security and sustainable development.Although increasing studies have been brought to ecological land,with few explorations of the relative importance of anthropogenic-natural factors and how they interact to induce the ecological land evolution.This research sought to fill this gap.In this study,18 factors,including the risk of goaf collapse,fault,prime croplands,were selected from six aspects of topography,geology,climate,accessibility,socio-economic and land control policies.logistic regression(LR)and random forest(RF)models were adopted to identify the anthropogenic and biophysical factors on the dynamic change of ecological land of Mentougou in Beijing from 1990 to 2018.The results show that there was a significant increase in ecological land from 1990 to 2018.The increased area of ecological land reached 102.11 km2 with an increased rate of 0.78,the gravity center of ecological land gradually moved to the northwest.The impact of anthropogenic factors on ecological land was greater than that of natural factors,ecological land was mainly driven by proportion of prime cropland,per capita GDP,land urbanization,temperature,per capita rural income,elevation and aspect factors.Additionally,slope and precipitation were also identified as important predictors for ecological land change.The model comparison suggested that RF can better identify the relationship between ecological land and explanatory variables than LR model.Based on our findings,the implementation of government policies along with anthropogenic factors are the most important variables influencing ecological land change,and the rational planning and allocation of ecological land by Mentougou government are still needed.展开更多
In order to improve classification accuracy, the regularized logistic regression is used to classify single-trial electroencephalogram （EEG）. A novel approach, named local sparse logistic regression （LSLR）, is pro...In order to improve classification accuracy, the regularized logistic regression is used to classify single-trial electroencephalogram （EEG）. A novel approach, named local sparse logistic regression （LSLR）, is proposed. The LSLR integrates the locality preserving projection regularization term into the framework of sparse logistic regression. It tries to maintain the neighborhood information of original feature space, and, meanwhile, keeps sparsity. The bound optimization algorithm and component-wise update are used to compute the weight vector in the training data, thus overcoming the disadvantage of the Newton-Raphson method and iterative re-weighted least squares （IRLS）. The classification accuracy of 80% is achieved using ten-fold cross-validation in the self-paced finger tapping data set. The results of LSLR are compared with SLR, showing the effectiveness of the proposed method.展开更多
BACKGROUND Acute kidney injury(AKI)has serious consequences on the prognosis of patients undergoing liver transplantation.Recently,artificial neural network(ANN)was reported to have better predictive ability than the ...BACKGROUND Acute kidney injury(AKI)has serious consequences on the prognosis of patients undergoing liver transplantation.Recently,artificial neural network(ANN)was reported to have better predictive ability than the classical logistic regression(LR)for this postoperative outcome.AIM To identify the risk factors of AKI after deceased-donor liver transplantation(DDLT)and compare the prediction performance of ANN with that of LR for this complication.METHODS Adult patients with no evidence of end-stage kidney dysfunction(KD)who underwent the first DDLT according to model for end-stage liver disease(MELD)score allocation system was evaluated.AKI was defined according to the International Club of Ascites criteria,and potential predictors of postoperative AKI were identified by LR.The prediction performance of both ANN and LR was tested.RESULTS The incidence of AKI was 60.6%(n=88/145)and the following predictors were identified by LR:MELD score>25(odds ratio[OR]=1.999),preoperative kidney dysfunction(OR=1.279),extended criteria donors(OR=1.191),intraoperative arterial hypotension(OR=1.935),intraoperative massive blood transfusion(MBT)(OR=1.830),and postoperative serum lactate(SL)(OR=2.001).The area under the receiver-operating characteristic curve was best for ANN(0.81,95%confidence interval[CI]:0.75-0.83)than for LR(0.71,95%CI:0.67-0.76).The root-mean-square error and mean absolute error in the ANN model were 0.47 and 0.38,respectively.CONCLUSION The severity of liver disease,pre-existing kidney dysfunction,marginal grafts,hemodynamic instability,MBT,and SL are predictors of postoperative AKI,and ANN has better prediction performance than LR in this scenario.展开更多
Transformation of land use/land cover change occurs due to the numbers and activities of people.Urban growth mod-eling has attracted substantial attention because it helps to comprehend the mechanisms of land use chan...Transformation of land use/land cover change occurs due to the numbers and activities of people.Urban growth mod-eling has attracted substantial attention because it helps to comprehend the mechanisms of land use change and thus helps relevant policies made.This paper tends to apply logistic regression to model urban growth in the Jiayu county of Hubei province,China.It is applied in a GIS environment to calculate variables and,then,in SPSS to discover the relationships between urban growth and the driving forces.The relative operating characteristic(ROC) shows the modeling accuracy with the curve 0.891 with standard er-ror 0.001.A probability map is generated finally to predict where urban growth will occur as a result of the computation.The result shows the model simulates urban growth well in the county scale.展开更多
For high-dimensional models with a focus on classification performance,the?1-penalized logistic regression is becoming important and popular.However,the Lasso estimates could be problematic when penalties of different...For high-dimensional models with a focus on classification performance,the?1-penalized logistic regression is becoming important and popular.However,the Lasso estimates could be problematic when penalties of different coefficients are all the same and not related to the data.We propose two types of weighted Lasso estimates,depending upon covariates determined by the Mc Diarmid inequality.Given sample size n and a dimension of covariates p,the finite sample behavior of our proposed method with a diverging number of predictors is illustrated by non-asymptotic oracle inequalities such as the?1-estimation error and the squared prediction error of the unknown parameters.We compare the performance of our method with that of former weighted estimates on simulated data,then apply it to do real data analysis.展开更多
This paper is devoted to identifying the biomarkers of rat liver regeneration via the adaptive logistic regression. By combining the adaptive elastic net penalty with the logistic regression loss, the adaptive logisti...This paper is devoted to identifying the biomarkers of rat liver regeneration via the adaptive logistic regression. By combining the adaptive elastic net penalty with the logistic regression loss, the adaptive logistic regression is proposed to adaptively identify the important genes in groups. Furthermore, by improving the pathwise coordinate descent algorithm, a fast solving algorithm is developed for computing the regularized paths of the adaptive logistic regression. The results from the experiments performed on the microarray data of rat liver regeneration are provided to illustrate the effectiveness of the proposed method and verify the biological rationality of the selected biomarkers.展开更多
With recent advances in biotechnology, genome-wide association study （GWAS） has been widely used to identify genetic variants that underlie human complex diseases and traits. In case-control GWAS, typical statistica...With recent advances in biotechnology, genome-wide association study （GWAS） has been widely used to identify genetic variants that underlie human complex diseases and traits. In case-control GWAS, typical statistical strategy is traditional logistical regression （LR） based on single-locus analysis. However, such a single-locus analysis leads to the well-known multiplicity problem, with a risk of inflating type I error and reducing power. Dimension reduction-based techniques, such as principal component-based logistic regression （PC-LR）, partial least squares-based logistic regression （PLS-LR）, have recently gained much attention in the analysis of high dimensional genomic data. However, the perfor- mance of these methods is still not clear, especially in GWAS. We conducted simulations and real data application to compare the type I error and power of PC-LR, PLS-LR and LR applicable to GWAS within a defined single nucleotide polymorphism （SNP） set region. We found that PC-LR and PLS can reasonably control type I error under null hypothesis. On contrast, LR, which is corrected by Bonferroni method, was more conserved in all simulation settings. In particular, we found that PC-LR and PLS-LR had comparable power and they both outperformed LR, especially when the causal SNP was in high linkage disequilibrium with genotyped ones and with a small effective size in simulation. Based on SNP set analysis, we applied all three methods to analyze non-small cell lung cancer GWAS data.展开更多
基金supported by the Shanghai Sailing Program(22YF1416300)Youth Fund Project of National Natural Science Foundation of China(32202117)+1 种基金National Key Research and Development Program of China(2022YFD2100104)the China Agriculture Research System(CARS-47).
文摘Bigeye tuna is a protein-rich fish that is susceptible to spoilage during cold storage,however,there is limited information on untargeted metabolomic profiling of bigeye tuna concerning spoilage-associated enzymes and metabolites.This study aimed to investigate how cold storage affects enzyme activities,nutrient composition,tissue microstructures and spoilage metabolites of bigeye tuna.The activities of cathepsins B,H,L increased,while Na^(+)/K^(+)-ATPase and Mg^(2+)-ATPase decreased,α-glucosidase,lipase and lipoxygenase first increased and then decreased during cold storage,suggesting that proteins undergo degradation and ATP metabolism occurs at a faster rate during cold storage.Nutrient composition(moisture and lipid content),total amino acids decreased,suggesting that the nutritional value of bigeye tuna was reduced.Besides,a logistic regression equation has been established as a food analysis tool and assesses the dynamics and correlation of the enzyme of bigeye tuna during cold storage.Based on untargeted metabolomic profiling analysis,a total of 524 metabolites were identified in the bigeye tuna contained several spoilage metabolites involved in lipid metabolism(glycerophosphocholine and choline phosphate),amino acid metabolism(L-histidine,5-deoxy-5′-(methylthio)adenosine,5-methylthioadenosine),carbohydrate metabolism(D-gluconic acid,α-D-fructose 1,6-bisphosphate,D-glyceraldehyde 3-phosphate).The results of tissue microstructures of tuna showed a looser network and visible deterioration of tissue fiber during cold storage.Therefore,metabolomic analysis and tissue microstructures provide insight into the spoilage mechanism investigations on bigeye tuna during cold storage.
基金This paper was financially supported by NSC96-2628-E-366-004-MY2 and NSC96-2628-E-132-001-MY2
文摘Internal solitary wave propagation over a submarine ridge results in energy dissipation, in which the hydrodynamic interaction between a wave and ridge affects marine environment. This study analyzes the effects of ridge height and potential energy during wave-ridge interaction with a binary and cumulative logistic regression model. In testing the Global Null Hypothesis, all values are p 〈0.001, with three statistical methods, such as Likelihood Ratio, Score, and Wald. While comparing with two kinds of models, tests values obtained by cumulative logistic regression models are better than those by binary logistic regression models. Although this study employed cumulative logistic regression model, three probability functions p^1, p^2 and p^3, are utilized for investigating the weighted influence of factors on wave reflection. Deviance and Pearson tests are applied to cheek the goodness-of-fit of the proposed model. The analytical results demonstrated that both ridge height （X1 ） and potential energy （X2 ） significantly impact （p 〈 0. 0001 ） the amplitude-based refleeted rate; the P-values for the deviance and Pearson are all 〉 0.05 （0.2839, 0.3438, respectively）. That is, the goodness-of-fit between ridge height （ X1 ） and potential energy （X2） can further predict parameters under the scenario of the best parsimonious model. Investigation of 6 predictive powers （ R2, Max-rescaled R^2, Sorners＇ D, Gamma, Tau-a, and c, respectively） indicate that these predictive estimates of the proposed model have better predictive ability than ridge height alone, and are very similar to the interaction of ridge height and potential energy. It can be concluded that the goodness-of-fit and prediction ability of the cumulative logistic regression model are better than that of the binary logistic regression model.
基金R&D Program for Forestry Technology funded by Korea Forest Service(Project No.S121012L100100)the framework of international cooperation program funded by National Research Foundation of Korea(2013K2A2A4000649,FY2013)
文摘With the well-being trends to pursue a healthy life, mountain ginseng(Panax ginseng) is rising as one of the most profitable forest products in South Korea. This study was aimed at evaluating a new methodology for identifying suitable sites for mountain ginseng cultivation in the country. Forest vegetation data were collected from 46 sites and the spatial distribution of all sites was analyzed using GIS data for topographic position, landform, solar radiation, and topographic wetness. The physical and chemical properties of the soil samples, including moisture content, p H, organic matter, total nitrogen, exchangeable cations, available phosphorous, and soil texture, were analyzed. The cultivation suitability at each site was assessed based on the environmental conditions using logistic regression(LR) and geographically weighted logistic regression(GWLR) and the results of both methods were compared. The results show that the areas with northern aspect and higher levels of solar radiation, moisture content, total nitrogen, and sand ratio are more likely to be identified as suitable sites for ginseng cultivation. In contrast to the LR, the spatial modeling with the GWLR results in an increase in the model fitness and indicates that a significant portion of spatialautocorrelation in the data decreases. A higher value of the area under the receiver operating characteristic(ROC) curve presents a better prediction accuracy of site suitability by the GWLR. The geographically weighted coefficient estimates of the model are nonstationary, and reveal that different site suitability is associated with the geographical location of the forest stands. The GWLR increases the accuracy of selecting suitable sites by considering the geographical variations in the characteristics of the cultivation sites.
基金supported by the National Natural Science Foundation of China[grant numbers 42101449,42090012 and 61825103]the Natural Science Foundation of Hubei Province,China[grant numbers 2022CFB773 and 2020CFA001]+2 种基金the Key Research and Development Program of Hubei Province,China[grant number 2022BAA048]the Chutian Scholar Program of Hubei Provincethe Yellow Crane Talent Scheme.
文摘Road traffic crashes are becoming thorny issues being faced worldwide.Traffic crashes are spatiotemporal events and the research on the spatiotemporal patterns and variation trends of traffic crashes has been carried out.However,the impact of built environment on traffic crash spatiotemporal trends has not received much attention.Moreover,the spatial non-stationarity between the variation trends of traffic crashes and their influencing factors is usually neglected.To make up for the lack of analysis of built environment factors influencing spatiotemporal hotspot trends in traffic crashes,this paper proposed a method of“ST-GWLR”for analyzing the influence of built environment factors on spatiotemporal hotspot trends of traffic crashes by combining the spatiotemporal hotspot trend analysis and Geographically Weighted Logistic Regression(GWLR)modeling methods.Firstly,the traffic crash spatiotemporal hotspot trends were explored using the space-time cube model,hotspot analysis,and Mann-Kendall trend test.Then,the GWLR was introduced to capture the spatial non-stationarity neglected by the classic Global Logistic Regression(GLR)model,to improve the accuracy of the model estimation.GWLR model is used for the first time to analyze the significant local correlation between the traffic crash spatiotemporal hotspot trends and the built environment factors,to accurately and effectively identify the built environment factors that have significant influences on the hotspot trends of traffic crashes.The performance of the GWLR models and GLR models was examined and compared sufficiently.The results showed that the proposed ST-GWLR,which captured spatial non-stationarity,performed better than the classic GLR combined with spatiotemporal analysis,and improved the prediction accuracy of the models by 14.9%,13.9%,and 15.1%,respectively.There were significant local correlations between intensifying hotspots and persistent hotspots of traffic crashes and the built environment factors.The findings of this paper have positive implications for traffic safety management and urban built environment planning.
基金supported by the Project of the 12th Five-year National Sci-Tech Support Plan of China(2011BAK12B09)China Special Project of Basic Work of Science and Technology(2011FY110100-2)
文摘Bailongjiang watershed in southern Gansu province, China, is one of the most landslide-prone regions in China, characterized by very high frequency of landslide occurrence. In order to predict the landslide occurrence, a comprehensive map of landslide susceptibility is required which may be significantly helpful in reducing loss of property and human life. In this study, an integrated model of information value method and logistic regression is proposed by using their merits at maximum and overcoming their weaknesses, which may enhance precision and accuracy of landslide susceptibility assessment. A detailed and reliable landslide inventory with 1587 landslides was prepared and randomly divided into two groups,(i) training dataset and(ii) testing dataset. Eight distinct landslide conditioning factors including lithology, slope gradient, aspect, elevation, distance to drainages,distance to faults, distance to roads and vegetation coverage were selected for landslide susceptibility mapping. The produced landslide susceptibility maps were validated by the success rate and prediction rate curves. The validation results show that the success rate and the prediction rate of the integrated model are 81.7 % and 84.6 %, respectively, which indicate that the proposed integrated method is reliable to produce an accurate landslide susceptibility map and the results may be used for landslides management and mitigation.
基金supported by State Key Fundamental Research Program (973) project (2008CB425802)the National natural Science Foundation of China (Grant No. 40801009)
文摘The Wenchuan earthquake on May 12,2008 caused numerous collapses,landslides,barrier lakes,and debris flows.Landslide susceptibility mapping is important for evaluation of environmental capacity and also as a guide for post-earthquake reconstruction.In this paper,a logistic regression model was developed within the framework of GIS to map landslide susceptibility.Qingchuan County,a heavily affected area,was selected for the study.Distribution of landslides was prepared by interpretation of multi-temporal and multi-resolution remote sensing images(ADS40 aerial imagery,SPOT5 imagery and TM imagery,etc.) and field surveys.The Certainly Factor method was used to find the influencial factors,indicating that lithologic groups,distance from major faults,slope angle,profile curvature,and altitude are the dominant factors influencing landslides.The weight of each factor was determined using a binomial logistic regression model.Landslide susceptibility mapping was based on spatial overlay analysis and divided into five classes.Major faults have the most significant impact,and landslides will occur most likely in areas near the faults.Onethird of the area has a high or very high susceptibility,located in the northeast,south and southwest,including 65.3% of all landslides coincident with the earthquake.The susceptibility map can reveal the likelihood of future failures,and it will be useful for planners during the rebuilding process and for future zoning issues.
基金Project supported by the Natural Science Foundation of ZhejiangProvince (No. 30295) and the Key Project of Zhejiang Province (No.011103192), China
文摘Landslide susceptibility map is one of the study fields portraying the spatial distribution of future slope failure sus- ceptibility. This paper deals with past methods for producing landslide susceptibility map and divides these methods into 3 types. The logistic linear regression approach is further elaborated on by crosstabs method, which is used to analyze the relationship between the categorical or binary response variable and one or more continuous or categorical or binary explanatory variables derived from samples. It is an objective assignment of coefficients serving as weights of various factors under considerations while expert opinions make great difference in heuristic approaches. Different from deterministic approach, it is very applicable to regional scale. In this study, double logistic regression is applied in the study area. The entire study area is first analyzed. The logistic regression equation showed that elevation, proximity to road, river and residential area are main factors triggering land- slide occurrence in this area. The prediction accuracy of the first landslide susceptibility map was showed to be 80%. Along the road and residential area, almost all areas are in high landslide susceptibility zone. Some non-landslide areas are incorrectly divided into high and medium landslide susceptibility zone. In order to improve the status, a second logistic regression was done in high landslide susceptibility zone using landslide cells and non-landslide sample cells in this area. In the second logistic regression analysis, only engineering and geological conditions are important in these areas and are entered in the new logistic regression equation indicating that only areas with unstable engineering and geological conditions are prone to landslide during large scale engineering activity. Taking these two logistic regression results into account yields a new landslide susceptibility map. Double logistic regression analysis improved the non-landslide prediction accuracy. During calculation of parameters for logistic regres- sion, landslide density is used to transform nominal variable to numeric variable and this avoids the creation of an excessively high number of dummy variables.
文摘Landslide susceptibility mapping is the first step in regional hazard management as it helps to understand the spatial distribution of the probability of slope failure in an area.An attempt is made to map the landslide susceptibility in Tevankarai Ar subwatershed,Kodaikkanal,India using binary logistic regression analysis.Geographic Information System is used to prepare the database of the predictor variables and landslide inventory map,which is used to build the spatial model of landslide susceptibility.The model describes the relationship between the dependent variable(presence and absence of landslide) and the independent variables selected for study(predictor variables) by the best fitting function.A forward stepwise logistic regression model using maximum likelihood estimation is used in the regression analysis.An inventory of 84 landslides and cells within a buffer distance of 10m around the landslide is used as the dependent variable.Relief,slope,aspect,plan curvature,profile curvature,land use,soil,topographic wetness index,proximity to roads and proximity to lineaments are taken as independent variables.The constant and the coefficient of the predictor variable retained by the regression model are used to calculate the probability of slope failure and analyze the effect of each predictor variable on landslide occurrence in thestudy area.The model shows that the most significant parameter contributing to landslides is slope.The other significant parameters are profile curvature,soil,road,wetness index and relief.The predictive logistic regression model is validated using temporal validation data-set of known landslide locations and shows an accuracy of 85.29 %.
基金supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions(164320H101)the Opening Fund of State Key Laboratory of Geohazard Prevention and Geoenvironment Protection of Chengdu University of Technology,China(SKLGP2012K012)+4 种基金the Opening Fund of Key Laboratory for Geo-hazards in Loess area(GLA2014005)the National Natural Science Foundation of China(No.40801212 and No.41201424)the 973 National Basic Research Program(Nos.2013CB733203,2013CB733204)the 863 National High-Tech Rand D Program(No.2012AA121302)the FP6 project"Mountain Risks"of the European Commission(No.MRTNCT-2006-035798)
文摘A detailed landslide susceptibility map was produced in the Youfang catchment using logistic regression method with datasets developed for a geographic information system(GIS).Known as one of the most landslide-prone areas in China, the Youfang catchment of Longnan mountain region,which lies in the transitional area among QinghaiTibet Plateau, loess Plateau and Sichuan Basin, was selected as a representative case to evaluate the frequency and distribution of landslides.Statistical relationships for landslide susceptibility assessment were developed using landslide and landslide causative factor databases.Logistic regression(LR)was used to create the landslide susceptibility maps based on a series of available data sources: landslide inventory; distance to drainage systems, faults and roads; slope angle and aspect; topographic elevation and topographical wetness index, and land use.The quality of the landslide susceptibility map produced in this paper was validated and the result can be used fordesigning protective and mitigation measures against landslide hazards.The landslide susceptibility map is expected to provide a fundamental tool for landslide hazards assessment and risk management in the Youfang catchment.
基金Under the auspices of the CAS Overseas Institutions Platform Project (No. 131C11KYSB20200033)the National Natural Science Foundation of China (No. 42071349)the Sichuan Science and Technology Program (No. 2020JDJQ0003)。
文摘Landslide distribution and susceptibility mapping are the fundamental steps for landslide-related hazard and disaster risk management activities, especially in the Himalaya region which has resulted in a great deal of death and damage to property. To better understand the landslide condition in the Nepal Himalaya, we carried out an investigation on the landslide distribution and susceptibility using the landslide inventory data and 12 different contributing factors in the Dailekh district, Western Nepal. Based on the evaluation of the frequency distribution of the landslide, the relationship between the landslide and the various contributing factors was determined.Then, the landslide susceptibility was calculated using logistic regression and statistical index methods along with different topographic(slope, aspect, relative relief, plan curvature, altitude, topographic wetness index) and non-topographic factors(distance from river, normalized difference vegetation index(NDVI), distance from road, precipitation, land use and land cover, and geology), and 470(70%) of total 658 landslides. The receiver operating characteristic(ROC) curve analysis using 198(30%) of total landslides showed that the prediction curve rates(area under the curve, AUC) values for two methods(logistic regression and statistical index) were 0.826, and 0.823with success rates of 0.793, and 0.811, respectively. The values of R-Index for the logistic regression and statistical index methods were83.66 and 88.54, respectively, consisting of high susceptible hazard classes. In general, this research concluded that the cohesive and coherent natural interplay of topographic and non-topographic factors strongly affects landslide occurrence, distribution, and susceptibility condition in the Nepal Himalaya region. Furthermore, the reliability of these two methods is verified for landslide susceptibility mapping in Nepal’s central mountain region.
基金funded by the National Research Council,Sri Lanka[NRC 17-066]。
文摘This study aimed to assess the potential of in-situ measured soil and vegetation characteristics in landslide susceptibility analyses.First,data for eight independent variables,i.e.,soil moisture content,soil organic content,compaction of soil(soil toughness),plant root strength,crop biomass,tree diameter at knee height,Shannon Wiener Index(SWI)for trees and herbs was assembled from field tests at two historic landslide locations:Aranayaka and Kurukudegama,Sri Lanka.An economical,finer resolution database was obtained as the field tests were not cost-prohibitive.The logistic regression(LR)analysis showed that soil moisture content,compaction of soil,SWI for trees and herbs were statistically significant at P<0.05.The variance inflation factors(VIFs)were computed to test for multicollinearity.VIF values(<2)confirmed the absence of multicollinearity between four independent variables in the LR model.Receiver Operating Characteristics(ROC)curve and Confusion Metrix(CM)methods were used to validate the model.In ROC analysis,areas under the curve of Success Rate Curve and Prediction Rate Curve were 84.5% and 96.6%,respectively,demonstrating the model’s excellent compatibility and predictability.According to the CM,the model demonstrated a 79.6% accuracy,63.6% precision,100% recall,and a F-measure of 77.8%.The model coefficients revealed that the vegetation cover has a more significant contribution to landslide susceptibility than soil characteristics.Finally,the susceptibility map,which was then classified as low,medium,and highly susceptible areas based on the natural breaks(Jenks)method,was generated using geographical information systems(GIS)techniques.All the historic landslide locations fell into the high susceptibility areas.Thus,validation of the model and inspection of the susceptibility map indicated that the in-situ soil and vegetation characteristics used in the model could be employed to demarcate historical landslide patches and identify landslide susceptible locations with high confidence.
基金supported by National Key Natural Science Foundation of China (Grant No. 50635010)
文摘The currently prevalent machine performance degradation assessment techniques involve estimating a machine＇s current condition based upon the recognition of indications of failure features,which entail complete data collected in different conditions.However,failure data are always hard to acquire,thus making those techniques hard to be applied.In this paper,a novel method which does not need failure history data is introduced.Wavelet packet decomposition（WPD） is used to extract features from raw signals,principal component analysis（PCA） is utilized to reduce feature dimensions,and Gaussian mixture model（GMM） is then applied to approximate the feature space distributions.Single-channel confidence value（SCV） is calculated by the overlap between GMM of the monitoring condition and that of the normal condition,which can indicate the performance of single-channel.Furthermore,multi-channel confidence value（MCV）,which can be deemed as the overall performance index of multi-channel,is calculated via logistic regression（LR） and that the task of decision-level sensor fusion is also completed.Both SCV and MCV can serve as the basis on which proactive maintenance measures can be taken,thus preventing machine breakdown.The method has been adopted to assess the performance of the turbine of a centrifugal compressor in a factory of Petro-China,and the result shows that it can effectively complete this task.The proposed method has engineering significance for machine performance degradation assessment.
基金supported by COMAC Beijing Aeronautical Science&Technology Research Institute。
文摘This paper proposed a new method for quantitative assessment of visual detectability of damage based on logistic regression,using the Probability of Detection(POD)as a criterion.Experiments were performed to establish the massive hit/miss data of visual inspection.Authoritative investigations verified the reliability of the data.The prediction function concluded comprises more than one flaw size parameters,including the depth and diameter of the dents.The results show that the depth and diameter of the dents are pivotal for the evaluation of detectability;the type of detection,the detection distance,and the qualifications of personnel are critical external factors to be considered.This function,with an accuracy rate of nearly 85%,is capable of predicting the visual detection probability of impact damage under various detection environments,which will provide a reference for the damage tolerance design of composite materials and field maintenance in the NonDestructive Testing(NDT)field.
基金funded by the National Natural Science Foundation of China(Grant No.41877533)。
文摘Ecological land is an important guarantee to maintain urban ecological security and sustainable development.Although increasing studies have been brought to ecological land,with few explorations of the relative importance of anthropogenic-natural factors and how they interact to induce the ecological land evolution.This research sought to fill this gap.In this study,18 factors,including the risk of goaf collapse,fault,prime croplands,were selected from six aspects of topography,geology,climate,accessibility,socio-economic and land control policies.logistic regression(LR)and random forest(RF)models were adopted to identify the anthropogenic and biophysical factors on the dynamic change of ecological land of Mentougou in Beijing from 1990 to 2018.The results show that there was a significant increase in ecological land from 1990 to 2018.The increased area of ecological land reached 102.11 km2 with an increased rate of 0.78,the gravity center of ecological land gradually moved to the northwest.The impact of anthropogenic factors on ecological land was greater than that of natural factors,ecological land was mainly driven by proportion of prime cropland,per capita GDP,land urbanization,temperature,per capita rural income,elevation and aspect factors.Additionally,slope and precipitation were also identified as important predictors for ecological land change.The model comparison suggested that RF can better identify the relationship between ecological land and explanatory variables than LR model.Based on our findings,the implementation of government policies along with anthropogenic factors are the most important variables influencing ecological land change,and the rational planning and allocation of ecological land by Mentougou government are still needed.
基金The National Natural Science Foundation of China(No.61075009)the Natural Science Foundation of Jiangsu Province(No.BK2011595)the Program for New Century Excellent Talents in University of China,the Qing Lan Project of Jiangsu Province
文摘In order to improve classification accuracy, the regularized logistic regression is used to classify single-trial electroencephalogram （EEG）. A novel approach, named local sparse logistic regression （LSLR）, is proposed. The LSLR integrates the locality preserving projection regularization term into the framework of sparse logistic regression. It tries to maintain the neighborhood information of original feature space, and, meanwhile, keeps sparsity. The bound optimization algorithm and component-wise update are used to compute the weight vector in the training data, thus overcoming the disadvantage of the Newton-Raphson method and iterative re-weighted least squares （IRLS）. The classification accuracy of 80% is achieved using ten-fold cross-validation in the self-paced finger tapping data set. The results of LSLR are compared with SLR, showing the effectiveness of the proposed method.
文摘BACKGROUND Acute kidney injury(AKI)has serious consequences on the prognosis of patients undergoing liver transplantation.Recently,artificial neural network(ANN)was reported to have better predictive ability than the classical logistic regression(LR)for this postoperative outcome.AIM To identify the risk factors of AKI after deceased-donor liver transplantation(DDLT)and compare the prediction performance of ANN with that of LR for this complication.METHODS Adult patients with no evidence of end-stage kidney dysfunction(KD)who underwent the first DDLT according to model for end-stage liver disease(MELD)score allocation system was evaluated.AKI was defined according to the International Club of Ascites criteria,and potential predictors of postoperative AKI were identified by LR.The prediction performance of both ANN and LR was tested.RESULTS The incidence of AKI was 60.6%(n=88/145)and the following predictors were identified by LR:MELD score>25(odds ratio[OR]=1.999),preoperative kidney dysfunction(OR=1.279),extended criteria donors(OR=1.191),intraoperative arterial hypotension(OR=1.935),intraoperative massive blood transfusion(MBT)(OR=1.830),and postoperative serum lactate(SL)(OR=2.001).The area under the receiver-operating characteristic curve was best for ANN(0.81,95%confidence interval[CI]:0.75-0.83)than for LR(0.71,95%CI:0.67-0.76).The root-mean-square error and mean absolute error in the ANN model were 0.47 and 0.38,respectively.CONCLUSION The severity of liver disease,pre-existing kidney dysfunction,marginal grafts,hemodynamic instability,MBT,and SL are predictors of postoperative AKI,and ANN has better prediction performance than LR in this scenario.
文摘Transformation of land use/land cover change occurs due to the numbers and activities of people.Urban growth mod-eling has attracted substantial attention because it helps to comprehend the mechanisms of land use change and thus helps relevant policies made.This paper tends to apply logistic regression to model urban growth in the Jiayu county of Hubei province,China.It is applied in a GIS environment to calculate variables and,then,in SPSS to discover the relationships between urban growth and the driving forces.The relative operating characteristic(ROC) shows the modeling accuracy with the curve 0.891 with standard er-ror 0.001.A probability map is generated finally to predict where urban growth will occur as a result of the computation.The result shows the model simulates urban growth well in the county scale.
基金Supported by the National Natural Science Foundation of China(61877023)the Fundamental Research Funds for the Central Universities(CCNU19TD009)。
文摘For high-dimensional models with a focus on classification performance,the?1-penalized logistic regression is becoming important and popular.However,the Lasso estimates could be problematic when penalties of different coefficients are all the same and not related to the data.We propose two types of weighted Lasso estimates,depending upon covariates determined by the Mc Diarmid inequality.Given sample size n and a dimension of covariates p,the finite sample behavior of our proposed method with a diverging number of predictors is illustrated by non-asymptotic oracle inequalities such as the?1-estimation error and the squared prediction error of the unknown parameters.We compare the performance of our method with that of former weighted estimates on simulated data,then apply it to do real data analysis.
基金supported by National Nature Science Foundation of China(No.61203293)Key Scientific and Technological Project of Henan Province(No.122102210131)+3 种基金Program for Science and Technology Innovation Talents in Universities of Henan Province(No.13HASTIT040)Foundation of Henan Educational Committee(No.13A120524)Henan Normal University Doctoral Topics(No.qd14156)Henan Higher School Funding Scheme for Young Teachers(No.2012GGJS-063)
文摘This paper is devoted to identifying the biomarkers of rat liver regeneration via the adaptive logistic regression. By combining the adaptive elastic net penalty with the logistic regression loss, the adaptive logistic regression is proposed to adaptively identify the important genes in groups. Furthermore, by improving the pathwise coordinate descent algorithm, a fast solving algorithm is developed for computing the regularized paths of the adaptive logistic regression. The results from the experiments performed on the microarray data of rat liver regeneration are provided to illustrate the effectiveness of the proposed method and verify the biological rationality of the selected biomarkers.
基金founded by the National Natural Science Foundation of China(81202283,81473070,81373102 and81202267)Key Grant of Natural Science Foundation of the Jiangsu Higher Education Institutions of China(10KJA330034 and11KJA330001)+1 种基金the Research Fund for the Doctoral Program of Higher Education of China(20113234110002)the Priority Academic Program for the Development of Jiangsu Higher Education Institutions(Public Health and Preventive Medicine)
文摘With recent advances in biotechnology, genome-wide association study （GWAS） has been widely used to identify genetic variants that underlie human complex diseases and traits. In case-control GWAS, typical statistical strategy is traditional logistical regression （LR） based on single-locus analysis. However, such a single-locus analysis leads to the well-known multiplicity problem, with a risk of inflating type I error and reducing power. Dimension reduction-based techniques, such as principal component-based logistic regression （PC-LR）, partial least squares-based logistic regression （PLS-LR）, have recently gained much attention in the analysis of high dimensional genomic data. However, the perfor- mance of these methods is still not clear, especially in GWAS. We conducted simulations and real data application to compare the type I error and power of PC-LR, PLS-LR and LR applicable to GWAS within a defined single nucleotide polymorphism （SNP） set region. We found that PC-LR and PLS can reasonably control type I error under null hypothesis. On contrast, LR, which is corrected by Bonferroni method, was more conserved in all simulation settings. In particular, we found that PC-LR and PLS-LR had comparable power and they both outperformed LR, especially when the causal SNP was in high linkage disequilibrium with genotyped ones and with a small effective size in simulation. Based on SNP set analysis, we applied all three methods to analyze non-small cell lung cancer GWAS data.
