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Linking Words in English
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作者 许崇玲 《疯狂英语(双语世界)》 2025年第3期25-29,37,共6页
Linking words,also called transition words,are quite useful in English expressions.Linking words are not the same as conjunctions,although some conjunctions can function as linking words.Here's a clear explanation... Linking words,also called transition words,are quite useful in English expressions.Linking words are not the same as conjunctions,although some conjunctions can function as linking words.Here's a clear explanation for English learners,followed by a wellorganized passage on the functions of linking words in writing and communication. 展开更多
关键词 functions linking words linking wordsalso CONJUNCTIONS english expressionslinking words transition wordsare linking words linking wordsheres transition words
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ESG赋能高校环境专业教学探索——基于“双碳”背景下环境未来发展国际前沿课程的实践
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作者 张晓媛 鲁金凤 刘雨 《高教学刊》 2026年第4期17-20,共4页
新工科教育理念的提出给环境专业改革带来新的挑战与契机,大类招生制度的实施则为跨学科融合和创新教学提供更广泛的空间。为提升环境专业的竞争力,该研究探讨如何有效将ESG内容融入环境专业教学。通过ESG融入的跨学科课程开发、AI赋能... 新工科教育理念的提出给环境专业改革带来新的挑战与契机,大类招生制度的实施则为跨学科融合和创新教学提供更广泛的空间。为提升环境专业的竞争力,该研究探讨如何有效将ESG内容融入环境专业教学。通过ESG融入的跨学科课程开发、AI赋能的项目式学习实践、跨学科合作、职业发展指导等创新教学方法,构建高校环境专业教学的LINK模式ESG应用策略,旨在增强学生在环境与可持续发展领域的职业竞争力。以“双碳”背景下环境未来发展国际前沿课程为例,详细探讨通过多元化教学资源、项目式学习与“开卷式”考核的方式,将ESG教学内容融入课程的过程和效果,为ESG赋能高校环境专业教学改革提供理论支持和实践参考。 展开更多
关键词 新工科教育 ESG赋能 跨学科融合 LINK模式 AI赋能
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Renovating Beijing’s South Central Axis
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作者 WANG YU 《China Today》 2026年第4期60-62,共3页
The South Central Axis in Beijing showcases China’s image and highlights its cultural confidence.THE Central Axis is the centerpiece of the Chinese capital’s urban spatial layout.The southern extended section of the... The South Central Axis in Beijing showcases China’s image and highlights its cultural confidence.THE Central Axis is the centerpiece of the Chinese capital’s urban spatial layout.The southern extended section of the Central Axis,or the South Central Axis,stretches from the Yongdingmen Gate Tower in the north to the South Fifth Ring Road in the south.While being a strategic transport link facilitating the coordinated development of the Beijing-Tianjin-Hebei region,it also showcases China’s vision for the future and highlights its cultural confidence. 展开更多
关键词 BEIJING central axis Cultural Confidence South Central Axis central axisor yongdingmen gate tower transport link Strategic Transport Link
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Innovation and Practice Research on the Modern Apprenticeship Training Model for Nursing Talents Integrating General-Specialty Integration, Moral-Technical Fusion, and Specialty-Innovation Union
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作者 Yuan Yuan Ling Shen Lei Yin 《Journal of Clinical and Nursing Research》 2026年第2期176-183,共8页
Modern apprenticeship emphasizes strengthening school-enterprise cooperation,deepening the integration of production and education,and promoting the combination of work and study to achieve seamless connection between... Modern apprenticeship emphasizes strengthening school-enterprise cooperation,deepening the integration of production and education,and promoting the combination of work and study to achieve seamless connection between professional education and industrial needs,thereby improving the quality of talent training.This paper analyzes the current problems in the nursing talent training system,elaborates on the significance of cultivating nursing talents based on modern apprenticeship,and proposes new ideas for constructing a modern apprenticeship training model for nursing talents from the perspectives of“integrating general and specialized education,merging virtue and skills,and linking specialization and innovation”.The aim is to further promote the organic combination of nursing talent training goals and post needs,for reference only. 展开更多
关键词 Integration of general and specialized education Merging of virtue and skills linking of specialization and innovation Nursing talent training Modern apprenticeship
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A Hybrid Clique-Based Method with Structural Feature Node Extraction for Community Detection in Overlapping Networks
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作者 Sicheng Ma Lixiang Zhang +3 位作者 Guocai Chen Zeyu Dai Junru Zhu Wei Fang 《Computers, Materials & Continua》 2026年第4期2231-2253,共23页
Community detection is a fundamental problem in network analysis for identifying densely connected node clusters,with successful applications in diverse fields like social networks,recommendation systems,biology,and c... Community detection is a fundamental problem in network analysis for identifying densely connected node clusters,with successful applications in diverse fields like social networks,recommendation systems,biology,and cyberattack detection.Overlapping community detection refers to the case of a node belonging to multiple communities simultaneously,which is a much more meaningful and challenging task.Graph representation learning with Evolutionary Computation has been studied well in overlapping community detection to deal with complex network structures and characteristics.However,most of them focus on searching the entire solution space,which can be inefficient and lead to inadequate results.To overcome the problem,a structural feature node extraction method is first proposed that can effectively map a network into a structural embedding space.Thus,nodes within the network are classified into hierarchical levels based on their structural feature strength,and only nodes with relatively high strength are considered in subsequent search steps to reduce the search space.Then,a maximal-clique representation method is employed on the given vertex set to identify overlapping nodes.A hybrid clique-based multi-objective evolutionary algorithmwith decomposition method is designed to address cliques and the remaining unexplored nodes separately.The number of communities generated with this allocation method is closer to the actual partition count with high division quality.Experimental results on nine usually used real-world networks,five synthetic networks,and two large-scale networks demonstrate the effectiveness of the proposed methodology in terms of community quality and algorithmic efficiency,compared to traditional,MOEA-based,and graph embedding-based community detection algorithms. 展开更多
关键词 Community detection graph embedding multi-objective evolutionary algorithm CLIQUES link strength
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Optimizing RPL Routing Using Tabu Search to Improve Link Stability and Energy Consumption in IoT Networks
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作者 Mehran Tarif Mohammadhossein Homaei +1 位作者 Abbas Mirzaei Babak Nouri-Moghaddam 《Computers, Materials & Continua》 2026年第4期2095-2126,共32页
The Routing Protocol for Low-power and Lossy Networks(RPL)is widely used in Internet of Things(IoT)systems,where devices usually have very limited resources.However,RPL still faces several problems,such as high energy... The Routing Protocol for Low-power and Lossy Networks(RPL)is widely used in Internet of Things(IoT)systems,where devices usually have very limited resources.However,RPL still faces several problems,such as high energy usage,unstable links,and inefficient routing decisions,which reduce the overall network performance and lifetime.In this work,we introduce TABURPL,an improved routing method that applies Tabu Search(TS)to optimize the parent selection process.The method uses a combined cost function that considers Residual Energy,Transmission Energy,Distance to the Sink,Hop Count,Expected Transmission Count(ETX),and Link Stability Rate(LSR).Simulation results show that TABURPL improves link stability,lowers energy consumption,and increases the packet delivery ratio compared with standard RPL and other existing approaches.These results indicate that Tabu Search can handle the complex trade-offs in IoT routing and can provide a more reliable solution for extending the network lifetime. 展开更多
关键词 Internet of things RPL protocol tabu search energy efficiency link stability multi-metric routing
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Constructions of Control Sequence Set for Hierarchical Access in Data Link Network
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作者 Niu Xianhua Ma Jiabei +3 位作者 Zhou Enzhi Wang Yaoxuan Zeng Bosen Li Zhiping 《China Communications》 2026年第1期67-80,共14页
As an important resource in data link,time slots should be strategically allocated to enhance transmission efficiency and resist eavesdropping,especially considering the tremendous increase in the number of nodes and ... As an important resource in data link,time slots should be strategically allocated to enhance transmission efficiency and resist eavesdropping,especially considering the tremendous increase in the number of nodes and diverse communication needs.It is crucial to design control sequences with robust randomness and conflict-freeness to properly address differentiated access control in data link.In this paper,we propose a hierarchical access control scheme based on control sequences to achieve high utilization of time slots and differentiated access control.A theoretical bound of the hierarchical control sequence set is derived to characterize the constraints on the parameters of the sequence set.Moreover,two classes of optimal hierarchical control sequence sets satisfying the theoretical bound are constructed,both of which enable the scheme to achieve maximum utilization of time slots.Compared with the fixed time slot allocation scheme,our scheme reduces the symbol error rate by up to 9%,which indicates a significant improvement in anti-interference and eavesdropping capabilities. 展开更多
关键词 control sequence data link hierarchical access control theoretical bound
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Modbus TCP和PLC Link通信技术在航天产品测试设备中的应用
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作者 邢化友 张晔 宋鹏涛 《自动化应用》 2026年第4期239-241,245,共4页
提出了基于以太网Modbus TCP和PLC Link通信技术的应用方案,利用台达PLC的PLC Link通信技术实现两台PLC之间实时数据的自动共享,以完成对大型网状天线驱动组件的功能和性能测试。主要测试其在不同负载下的输出力矩、驱动电压、驱动电流... 提出了基于以太网Modbus TCP和PLC Link通信技术的应用方案,利用台达PLC的PLC Link通信技术实现两台PLC之间实时数据的自动共享,以完成对大型网状天线驱动组件的功能和性能测试。主要测试其在不同负载下的输出力矩、驱动电压、驱动电流、电机转速和输出转速。磁粉制动器为系统提供负载,下位机主站PLC通过模拟量采集模块实时采集扭矩传感器的扭矩信号,并与磁粉制动器提供的负载形成PID闭环控制,实现负载的自动加载。下位机从站PLC负责程控电源的电压电流控制,利用输出端光电编码器实时采集输出转速。最终,通过LabVIEW平台开发的专用测试软件,结合Modbus TCP总线对下位机主从站PLC进行实时采集和控制,实现上位机与下位机主从站PLC之间的数据交互。通过在驱动组件产品热真空试验中的实际应用,证明了该通信技术的有效性。 展开更多
关键词 Modbus TCP PLC Link LabVIEW PID 扭矩传感器 磁粉制动器
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Seismic design and performance of building structures with self-centering steel-concrete hybrid single-pier coupled walls
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作者 Mojtaba Farahi Fabio Freddi Massimo Latour 《Resilient Cities and Structures》 2026年第1期85-101,共17页
In response to the demand for seismic-resilient structures,various innovative solutions have emerged to reduce local damage and residual deformations,facilitating repair operations in the aftermath of high-intensity e... In response to the demand for seismic-resilient structures,various innovative solutions have emerged to reduce local damage and residual deformations,facilitating repair operations in the aftermath of high-intensity earth-quakes.This paper examines the seismic performance of a steel-concrete hybrid wall system equipped with a selfcentering solution to mitigate earthquake-induced residual deformations.The considered hybrid system includes a Reinforced Concrete(RC)shear wall with two steel side columns connected by coupling steel beams.In this study,a novel type of coupling beams featuring a friction-damped self-centering system is implemented.The system is referred to as Self-Centering Hybrid Single-Pier Coupled Wall(SC-SP-HCW)and aims to minimize damage and residual deformations after earthquakes,which in turn facilitates repairs and enhances seismic resilience.Unlike conventional self-centering coupling beams with post-tensioned tendons,the self-centering configuration in this system does not rely on a gap-opening mechanism at the wall-beam connection interface,eliminating frame expansion effects.The proposed self-centering devices can also be implemented as preassembled links,which facilitates installation and reduces uncertainties associated with the on-site posttensioning procedure.The seismic performance of SC-SP-HCWs is investigated through nonlinear static and incremental dynamic analyses on case study SC-SP-HCWs designed as the lateral load-resisting systems of an eight-story building.The seismic response of the case study SC-SP-HCWs is investigated,considering both local and global engineering demand parameters(EDPs).The results demonstrate the ability of the SC-SP-HCWs to significantly reduce earthquake-induced residual deformations without exacerbating damage to structural ele-ments typically observed in conventional coupled walls. 展开更多
关键词 Hybrid coupled walls Damage-free self-centering links Friction devices Seismic performance Reinforced concrete walls
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Learning Time Embedding for Temporal Knowledge Graph Completion
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作者 Jinglu Chen Mengpan Chen +2 位作者 Wenhao Zhang Huihui Ren Daniel Dajun Zeng 《Computers, Materials & Continua》 2026年第2期827-851,共25页
Temporal knowledge graph completion(TKGC),which merges temporal information into traditional static knowledge graph completion(SKGC),has garnered increasing attention recently.Among numerous emerging approaches,transl... Temporal knowledge graph completion(TKGC),which merges temporal information into traditional static knowledge graph completion(SKGC),has garnered increasing attention recently.Among numerous emerging approaches,translation-based embedding models constitute a prominent approach in TKGC research.However,existing translation-based methods typically incorporate timestamps into entities or relations,rather than utilizing them independently.This practice fails to fully exploit the rich semantics inherent in temporal information,thereby weakening the expressive capability of models.To address this limitation,we propose embedding timestamps,like entities and relations,in one or more dedicated semantic spaces.After projecting all embeddings into a shared space,we use the relation-timestamp pair instead of the conventional relation embedding as the translation vector between head and tail entities.Our method elevates timestamps to the same representational significance as entities and relations.Based on this strategy,we introduce two novel translation-based embedding models:TE-TransR and TE-TransT.With the independent representation of timestamps,our method not only enhances capabilities in link prediction but also facilitates a relatively underexplored task,namely time prediction.To further bolster the precision and reliability of time prediction,we introduce a granular,time unit-based timestamp setting and a relation-specific evaluation protocol.Extensive experiments demonstrate that our models achieve strong performance on link prediction benchmarks,with TE-TransR outperforming existing baselines in the time prediction task. 展开更多
关键词 Temporal knowledge graph(TKG) TKG embedding model link prediction time prediction
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Cascading failure modeling and survivability analysis of weak-communication underwater unmanned swarm networks
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作者 Yifan Yuan Xiaohong Shen +3 位作者 Lin Sun Ke He Yongsheng Yan Haiyan Wang 《Defence Technology(防务技术)》 2026年第2期66-82,共17页
Cascading failures pose a serious threat to the survivability of underwater unmanned swarm networks(UUSNs),significantly limiting their service ability in collaborative missions such as military reconnaissance and env... Cascading failures pose a serious threat to the survivability of underwater unmanned swarm networks(UUSNs),significantly limiting their service ability in collaborative missions such as military reconnaissance and environmental monitoring.Existing failure models primarily focus on power grids and traffic systems,and don't address the unique challenges of weak-communication UUSNs.In UUSNs,cascading failure present a complex and dynamic process driven by the coupling of unstable acoustic channels,passive node drift,adversarial attacks,and network heterogeneity.To address these challenges,a directed weighted graph model of UUSNs is first developed,in which node positions are updated according to ocean-current-driven drift and link weights reflect the probability of successful acoustic transmission.Building on this UUSNs graph model,a cascading failure model is proposed that integrates a normal-failure-recovery state-cycle mechanism,multiple attack strategies,and routingbased load redistribution.Finally,under a five-level connectivity UUSNs scheme,simulations are conducted to analyze how dynamic topology,network load,node recovery delay,and attack modes jointly affect network survivability.The main findings are:(1)moderate node drift can improve survivability by activating weak links;(2)based-energy routing(BER)outperform based-depth routing(BDR)in harsh conditions;(3)node self-recovery time is critical to network survivability;(4)traditional degree-based critical node metrics are inadequate for weak-communication UUSNs.These results provide a theoretical foundation for designing robust survivability mechanisms in weak-communication UUSNs. 展开更多
关键词 Weak communication Underwater unmanned swarm networks(UUSNs) Link success probability Cascading failure Node self-recovery Survivability analysis
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CEFCO 2026 An Era of Transformation:Stronger Links,Smarter Futures
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作者 Zhou Dongyang 《China's Foreign Trade》 2026年第1期8-10,共3页
The China Expo Forum for International Cooperation(CEFCO)2026 was held in Wuhan,Hubei Province,China,on January 22.The opening ceremony was attended by Li Qing Shuang,Vice President of the China Council for the Promot... The China Expo Forum for International Cooperation(CEFCO)2026 was held in Wuhan,Hubei Province,China,on January 22.The opening ceremony was attended by Li Qing Shuang,Vice President of the China Council for the Promotion of International Trade(CCPIT);Zhu Yuji,Deputy Secretary of the Hubei Provincial Committee of the Communist Party of China;Sheng Yue Chun,Member of the Standing Committee of the Hubei Provincial Committee of the Communist Party of China and Secretary of the Wuhan Municipal Committee;Punita Bhansal,President of the Global Association of the Exhibition Industry(UFI);Marsha Flanagan,President and CEO of the International Association of Exhibitions and Events(IAEE);Vincent Polito,CEO of the Society of Independent Show Organizers(SISO);and Leonie Ashford,Board Member of the International Congress and Convention Association(ICCA). 展开更多
关键词 smarter futures China expo forum international cooperation cefco exhibition industry wuhan stronger links international cooperation TRANSFORMATION global association exhibition industry ufi
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Unit-Linking PCNN中的彩色图像边缘检测 被引量:2
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作者 薛锦树 聂仁灿 +1 位作者 周冬明 赵东风 《计算机工程与应用》 CSCD 北大核心 2011年第17期188-191,共4页
PCNN模型具有相似群神经元同步发放脉冲的特性,适合于图像分割。对彩色图像的亮度分量进行对数变换,使其更符合人眼的视觉特性;在PCNN进行彩色图像R、G、B三分量分割的过程中,利用遗传算法进行神经元关键参数的选择,利用偏态指标进行迭... PCNN模型具有相似群神经元同步发放脉冲的特性,适合于图像分割。对彩色图像的亮度分量进行对数变换,使其更符合人眼的视觉特性;在PCNN进行彩色图像R、G、B三分量分割的过程中,利用遗传算法进行神经元关键参数的选择,利用偏态指标进行迭代控制;在Unit-Linking PCNN模型中实现R、G、B三分量分割图的边缘检测,利用加权合并策略得到最终的边缘检测结果。仿真结果表明,该方法得到的结果体现了图像中更多的轮廓细节,具有很好的自适应性。 展开更多
关键词 Unit—linking脉冲耦合神经网络 RGB空间 彩色图像分割 彩色图像边缘检测
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A Brief Analysis of the Self-correction Model——from the View of Linking Theory
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作者 佘阿莉 《教师》 2017年第32期78-79,共2页
Based on the theory of the post method pedagogy and the teaching practice,this paper proposes a new teaching model,the self-correction model,and explains it from the point of view of linking theory.
关键词 SELF-CORRECTION model linking THEORY CONCEPT implications
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Modeling online social networks based on preferential linking 被引量:2
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作者 胡海波 郭进利 陈骏 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第11期573-578,共6页
We study the phenomena of preferential linking in a large-scale evolving online social network and find that the linear preference holds for preferential creation, preferential acceptance, and preferential attachment.... We study the phenomena of preferential linking in a large-scale evolving online social network and find that the linear preference holds for preferential creation, preferential acceptance, and preferential attachment. Based on the linear preference, we propose an analyzable model, which illustrates the mechanism of network growth and reproduces the process of network evolution. Our simulations demonstrate that the degree distribution of the network produced by the model is in good agreement with that of the real network. This work provides a possible bridge between the micro=mechanisms of network growth and the macrostructures of online social networks. 展开更多
关键词 online social network preferential linking MODEL power law
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Corneal collagen cross-linking in patients with keratoconus from the Dresden protocol to customized solutions:theoretical basis 被引量:2
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作者 Ciro Caruso Luca D’Andrea +4 位作者 Mario Troisi Michele Rinaldi Raffaele Piscopo Salvatore Troisi Ciro Costagliola 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第5期951-962,共12页
Keratoconus is an ectatic condition characterized by gradual corneal thinning,corneal protrusion,progressive irregular astigmatism,corneal fibrosis,and visual impairment.The therapeutic options regarding improvement o... Keratoconus is an ectatic condition characterized by gradual corneal thinning,corneal protrusion,progressive irregular astigmatism,corneal fibrosis,and visual impairment.The therapeutic options regarding improvement of visual function include glasses or soft contact lenses correction for initial stages,gas-permeable rigid contact lenses,scleral lenses,implantation of intrastromal corneal ring or corneal transplants for most advanced stages.In keratoconus cases showing disease progression corneal collagen crosslinking(CXL)has been proven to be an effective,minimally invasive and safe procedure.CXL consists of a photochemical reaction of corneal collagen by riboflavin stimulation with ultraviolet A radiation,resulting in stromal crosslinks formation.The aim of this review is to carry out an examination of CXL methods based on theoretical basis and mathematical models,from the original Dresden protocol to the most recent developments in the technique,reporting the changes proposed in the last 15y and examining the advantages and disadvantages of the various treatment protocols.Finally,the limits of non-standardized methods and the perspectives offered by a customization of the treatment are highlighted. 展开更多
关键词 corneal collagen cross linking KERATOCONUS custom fast protocol Dresden protocol lambert-beer law Bunsen-roscoe law
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A multi-attention RNN-based relation linking approach for question answering over knowledge base 被引量:2
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作者 Li Huiying Zhao Man Yu Wenqi 《Journal of Southeast University(English Edition)》 EI CAS 2020年第4期385-392,共8页
Aiming at the relation linking task for question answering over knowledge base,especially the multi relation linking task for complex questions,a relation linking approach based on the multi-attention recurrent neural... Aiming at the relation linking task for question answering over knowledge base,especially the multi relation linking task for complex questions,a relation linking approach based on the multi-attention recurrent neural network(RNN)model is proposed,which works for both simple and complex questions.First,the vector representations of questions are learned by the bidirectional long short-term memory(Bi-LSTM)model at the word and character levels,and named entities in questions are labeled by the conditional random field(CRF)model.Candidate entities are generated based on a dictionary,the disambiguation of candidate entities is realized based on predefined rules,and named entities mentioned in questions are linked to entities in knowledge base.Next,questions are classified into simple or complex questions by the machine learning method.Starting from the identified entities,for simple questions,one-hop relations are collected in the knowledge base as candidate relations;for complex questions,two-hop relations are collected as candidates.Finally,the multi-attention Bi-LSTM model is used to encode questions and candidate relations,compare their similarity,and return the candidate relation with the highest similarity as the result of relation linking.It is worth noting that the Bi-LSTM model with one attentions is adopted for simple questions,and the Bi-LSTM model with two attentions is adopted for complex questions.The experimental results show that,based on the effective entity linking method,the Bi-LSTM model with the attention mechanism improves the relation linking effectiveness of both simple and complex questions,which outperforms the existing relation linking methods based on graph algorithm or linguistics understanding. 展开更多
关键词 question answering over knowledge base(KBQA) entity linking relation linking multi-attention bidirectional long short-term memory(Bi-LSTM) large-scale complex question answering dataset(LC-QuAD)
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Correlation between corneal demarcation line depth in epithelium-off and trans-epithelium accelerated corneal cross linking and keratoconus progression 被引量:2
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作者 Mahmoud Abdel-Radi Zeiad Eldaly +3 位作者 Hazem Abdelmotaal Reham Abdelrahman Mohamed Sayed Kamel Soliman 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2020年第6期907-912,共6页
AIM:To compare corneal demarcation line(DL)depth in both accelerated epithelium-off and trans-epithelium cross linking(CXL)using anterior segment optical coherence tomography(AS-OCT)and its relation to maximum keratom... AIM:To compare corneal demarcation line(DL)depth in both accelerated epithelium-off and trans-epithelium cross linking(CXL)using anterior segment optical coherence tomography(AS-OCT)and its relation to maximum keratometry(Kmax)progression in both techniques.METHODS:A prospective comparative interventional study where patients with mild to moderate keratoconus(KC)were classified into two groups:accelerated epitheliumoff and trans-epithelium CXL based on corneal pachymetry.Assessment of corneal DL depth was carried out after 3mo by AS-OCT.Kmax readings were evaluated after one year follow up using the Scheimpflug imaging system.RESULTS:Study included 74 eyes of 44 patients.Group A underwent epithelium-off CXL(41 eyes),while Group B underwent trans-epithelium CXL(33 eyes).At 3mo follow up,mean corneal DL depth in Group A was 219.9±58.4μm while in Group B was 127.2±7.8μm(P<0.05).The mean Kmaxchangedfrom51.9±3.9to51.3±4.2dioptersin Group A and from 53.1±4.1 to 53.6±5 diopters in Group B with insignificant difference in Kmax changes in either group(P>0.05).In addition,no significant change in corneal pachymetry was found in both groups(meanchange at 1y:6.4±4.7 and-10.1±2.3μm in Groups A and B respectively).CONCLUSION:Despite a significantly deeper corneal DL depth created by accelerated epithelium-off CXL technique compared to accelerated trans-epithelium CXL,there is no significant impact on keratoconus progression. 展开更多
关键词 anterior segment optical coherence tomography cross linking demarcation line KERATOCONUS
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Preparation of cross-linked enzyme aggregates of nitrile hydratase ES-NHT-118 from E.coli by macromolecular cross-linking agent 被引量:5
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作者 Liya Zhou Haixia Mou +3 位作者 Jing Gao Li Ma Ying He Yanjun Jiang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2017年第4期487-492,共6页
Cross-linked enzyme aggregates(CLEAs) of nitrile hydratase(NHase) ES-NHT-118 from Escherichia coli were prepared by using ammonium sulfate as precipitating agent followed by cross-linking with dextran polyaldehyde for... Cross-linked enzyme aggregates(CLEAs) of nitrile hydratase(NHase) ES-NHT-118 from Escherichia coli were prepared by using ammonium sulfate as precipitating agent followed by cross-linking with dextran polyaldehyde for the first time. In this process, egg white was added as protein feeder for facilitating the formation of CLEAs. The optimal conditions of the immobilization process were determined. Michaelis constants(Km) of free NHase and NHase CLEAs were also determined. The NHase CLEAs exhibited increased stability at varied pH and temperature conditions compared to its free counterpart. When exposed to high concentrations of acrylamide, NHase CLEAs also exhibited effective catalytic activity. 展开更多
关键词 nitrile linking acrylamide linker ammonium facilitating counterpart Michaelis dextran constants
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Accelerated versus standard corneal cross linking in the treatment of ectasia post refractive surgery and penetrating keratoplasty: a medium term randomized trial 被引量:1
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作者 Hany A.Khairy Moataz F.Elsawy +2 位作者 Khaled Said-Ahmed Marwa A.Zaki Sameh S Mandour 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2019年第11期1714-1719,共6页
AIM: To compare the clinical outcomes of the standard corneal cross linking(CXL) and the accelerated CXL in patients with progressive corneal ectasia post refractive surgery and penetrating keratoplasty.METHODS: Total... AIM: To compare the clinical outcomes of the standard corneal cross linking(CXL) and the accelerated CXL in patients with progressive corneal ectasia post refractive surgery and penetrating keratoplasty.METHODS: Totally 120 eyes of 83 patients scheduled to receive either standard CXL(3 m W/cm^2 for a period of 30 min) or accelerated CXL(18 m W/cm2 for a period of 5 min). The main outcomes for comparison were the change in: maximum-K reading(K-max), manifest refractive spherical equivalent(SE), central corneal thickness(CCT), and the best corrected distance visual acuity(CDVA).RESULTS: One hundred and eleven eyes completed the study. The main outcome measurement was the K-max reading. Both group showed significant improvement in the value postoperatively at 6 and 12 mo. The mean change in the standard group was 1.21±0.11 D and in the accelerated group was 0.90±0.05 D at the end of 12 mo postoperatively, with no statistically significant difference between the 2 groups. Similarly, CDVA improved significantly from their preoperative value in the standard group by 2.98±0.11 letters, and in the accelerated group by 2.20±0.06 letters, with no statistically significant difference between the two groups. Both of the SE, and CCT showed no statistically significant difference at the end of follow up period in each group.CONCLUSION: Both standard CXL and accelerated CXL are safe and effective treatment in halting ectasia after corneal refractive surgery. The accelerated CXL results are comparable to the standard CXL with short time exposure of the cornea to ultraviolet irradiation, leading to reduced operation time, reduced operative ocular discomfort, and corneal haze. 展开更多
关键词 CORNEAL cross linking ACCELERATED refractivesurgery PENETRATING KERATOPLASTY CORNEAL ECTASIA
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