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A New Design Approach for Nearly Linear Phase Stable IIR Filter using Fractional Derivative 被引量:1
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作者 Nikhil Agrawal Anil Kumar Varun Bajaj 《IEEE/CAA Journal of Automatica Sinica》 EI CSCD 2020年第2期527-538,共12页
In this paper,a new design method for digital infinite impulse response(IIR)filters with nearly linear-phase response is presented using fractional derivative constraints(FDCs).In the proposed method,design problem of... In this paper,a new design method for digital infinite impulse response(IIR)filters with nearly linear-phase response is presented using fractional derivative constraints(FDCs).In the proposed method,design problem of an IIR frlter is constructed as the minimization of phase error between the desired and designed phase response of an allpass filter(APF)such that the designed lowpass filter(LPF)or highpass frlter(HPF)yields less passband(ep),and stopband errors(es)with optimal stopband attenuation(As).In order to have accurate passband(pb)response,FDCs are imposed on appropriate reference frequency,where the optimality of these FDCs are ensured by using a new greedy based sorting mechanism.The simulated results reflect the efficiency of the proposed method in term of improved passband response along with better transition width.However,small reduction in^is observed within the allowable limit,when compared to noin-fractional design approach,but the designed filter remains immune to wordlength(WL)effect. 展开更多
关键词 Fractional derivative constraint(FDC) infinite impulse response(IIR)filter least squared linear phase QUANTIZATION
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A simple algorithm to calculate the pulsed sound field of a wide-band linear phased array
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作者 黄晶 阙沛文 +2 位作者 张志钢 雷华明 金建华 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2006年第4期427-430,共4页
A simple algorithm using an impulse response for a rectangular piston element is discussed. The impulse response of linear phased array is obtained hv stumming the impulse responses of rectangular piston elements with... A simple algorithm using an impulse response for a rectangular piston element is discussed. The impulse response of linear phased array is obtained hv stumming the impulse responses of rectangular piston elements with different delay times. The output response of the linear wide-band array is equal to the convolution of impulse response functions with wide-band pulse exeiting signal. Sound field distributions and impulse responses of three kinds of transducers are compared. The results can be used to optimize the parameters of the linear phased array transducers used in uhrasonie imaging in nondestructive testing (NDT). 展开更多
关键词 linear phased array ultrasonic transducer impulse response sound field
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Ultrasonic beam focusing characteristics of shear-vertical waves for contact-type linear phased array in solid 被引量:2
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作者 Yu-Xiang Dai Shou-Guo Yan Bi-Xing Zhang 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第3期270-276,共7页
We investigate the beam focusing technology of shear-vertical(SV) waves for a contact-type linear phased array to overcome the shortcomings of conventional wedge transducer arrays. The numerical simulation reveals the... We investigate the beam focusing technology of shear-vertical(SV) waves for a contact-type linear phased array to overcome the shortcomings of conventional wedge transducer arrays. The numerical simulation reveals the transient excitation and propagation characteristics of SV waves. It is found that the element size plays an important role in determining the transient radiation directivity of SV waves. The transient beam focusing characteristics of SV waves for various array parameters are deeply studied. It is particularly interesting to see that smaller element width will provide the focused beam of SV waves with higher quality, while larger element width may result in erratic fluctuation of focusing energy around the focal point. There exists a specific range of inter-element spacing for optimum focusing performance. Moreover, good beam focusing performance of SV waves can be achieved only at high steering angles. 展开更多
关键词 beam focusing shear-vertical(SV)waves contact-type linear phased array SOLID
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General FIR Filter Design with Linear Phase in Passband by Water Cycle Algorithm
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作者 Haijiang Hu Shaojing Song Yumei Gong 《Journal of Computer and Communications》 2018年第11期326-331,共6页
FIR filter is an important type of filter in the field of signal processing because of its inherent stability, simpler structure, and easier implementation on linear phase. WCA is used to solve FIR filter design with ... FIR filter is an important type of filter in the field of signal processing because of its inherent stability, simpler structure, and easier implementation on linear phase. WCA is used to solve FIR filter design with low magnitude error and linear phase in passband. This method uses WCA to optimize the filter coefficient based on the low magnitude errors in all frequency domains. Moreover, in the constraint conditions, the least group delay in passband is used for the optimization. The experiments testify this method has good performance on the passband error and group delay error in the passband. Therefore this method is an efficient algorithm for FIR filter optimization which can be used in the digital signal processing widely. 展开更多
关键词 FIR WCA linear phase Optimization
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Non-Linear Phase Tomography Based on Fréchet Derivative
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作者 Valentina Davidoiu Bruno Sixou +1 位作者 Max Langer Franoise Peyrin 《Advances in Computed Tomography》 2014年第4期39-50,共12页
Phase imaging coupled to micro-tomography acquisition has emerged as a powerful tool to investigate specimens in a non-destructive manner. While the intensity data can be acquired and recorded, the phase information o... Phase imaging coupled to micro-tomography acquisition has emerged as a powerful tool to investigate specimens in a non-destructive manner. While the intensity data can be acquired and recorded, the phase information of the signal has to be “retrieved” from the data modulus only. Phase retrieval is an ill-posed non-linear problem and regularization techniques including a priori knowledge are necessary to obtain stable solutions. Several linear phase recovery methods have been proposed and it is expected that some limitations resulting from the linearization of the direct problem will be overcome by taking into account the non-linearity of the phase problem. To achieve this goal, we propose and evaluate a non-linear algorithm for in-line phase micro-tomography based on an iterative Landweber method with an analytic calculation of the Fréchet derivative of the phase-intensity relationship and of its adjoint. The algorithm was applied in the projection space using as initialization the linear mixed solution. The efficacy of the regularization scheme was evaluated on simulated objects with a slowly and a strongly varying phase. Experimental data were also acquired at ESRF using a propagation-based X-ray imaging technique for the given pixel size 0.68 μm. Two regularization scheme were considered: first the initialization was obtained without any prior on the ratio of the real and imaginary parts of the complex refractive index and secondly a constant a priori value was assumed on ?. The tomographic central slices of the refractive index decrement were compared and numerical evaluation was performed. The non-linear method globally decreases the reconstruction errors compared to the linear algorithm and is achieving better reconstruction results if no prior is introduced in the initialization solution. For in-line phase micro-tomography, this non-linear approach is a new and interesting method in biomedical studies where the exact value of the a priori ratio is not known. 展开更多
关键词 phase Retrieval In-Line phase TOMOGRAPHY Inverse Problems NON-linear Problem NON-linear Optimization Fréchet DERIVATIVE Coherent IMAGING FRESNEL Diffraction phase Contrast X-Ray IMAGING
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Construction of Two-Dimensional Compactly Supported Orthogonal Wavelets Filters with Linear Phase 被引量:8
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作者 Si Long PENG Institute of Automation, Academia Sinica, Beijing 100080. P. R. China 《Acta Mathematica Sinica,English Series》 SCIE CSCD 2002年第4期719-726,共8页
In this paper, at large class of two-dimensional orthogonal wavelet filters, (lowpass and highpass), are presented in explicit expression. We also characterize the filters with linear phase in this case. Some examples... In this paper, at large class of two-dimensional orthogonal wavelet filters, (lowpass and highpass), are presented in explicit expression. We also characterize the filters with linear phase in this case. Some examples are also given, including non-separable filters with linear phase. 展开更多
关键词 TWO-DIMENSIONAL ORTHOGONAL linear phase WAVELET FILTERS
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Design of Perfect Reconstruction Cosine Modulated Filter Bank with Linear Phase
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作者 Tan, Ying 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 1998年第1期24-30,共7页
We propose the quadratic constrained formulas for the design of linear phase cosine modulated paraunitary filter banks given in references . Using these formulae, we can, directly, optimize the prototype filter coeff... We propose the quadratic constrained formulas for the design of linear phase cosine modulated paraunitary filter banks given in references . Using these formulae, we can, directly, optimize the prototype filter coefficients in a quadratic form. A design example is also given to demonstrate these formulae in this paper. 展开更多
关键词 Quadratic constrained formula linear phase Perfect reconstruction Cosine modulated FB.
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A Construction Method of Wavelet with Linear Phase
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作者 匡正 李云晖 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 1997年第4期4-6,共3页
H(ω) |is chosen as a filter for filter H(ω) ,and |H(ω)| is a even function when H(ω) is a real coefficient rational function of e -iω ,and so the scaling and wavelet functions corresponding to | H... H(ω) |is chosen as a filter for filter H(ω) ,and |H(ω)| is a even function when H(ω) is a real coefficient rational function of e -iω ,and so the scaling and wavelet functions corresponding to | H(ω) | possess linear phases. An algorithm is given for computation of wavelet at very low cost. 展开更多
关键词 WAVELET SYMMETRIC WAVELET linear phase
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Multi-Level Inverter Linear Predictive Phase Composition Strategy for UPQC
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作者 M.Hari Prabhu K.Sundararaju 《Intelligent Automation & Soft Computing》 SCIE 2023年第6期2947-2958,共12页
The power system is facing numerous issues when the distributed gen-eration is added to the existing system.The existing power system has not been planned with flawless power quality control.These restrictions in the ... The power system is facing numerous issues when the distributed gen-eration is added to the existing system.The existing power system has not been planned with flawless power quality control.These restrictions in the power trans-mission generation system are compensated by the use of devices such as the Static Synchronous Compensator(STATCOM),the Unified Power Quality Con-ditioner(UPQC)series/shunt compensators,etc.In this work,UPQC’s plan with the joint activity of photovoltaic(PV)exhibits is proposed.The proposed system is made out of series and shunt regulators and PV.A boost converter connects the DC link to the PV source,allowing it to compensate for voltage sags,swells,vol-tage interferences,harmonics,and reactive power issues.In this paper,the fea-tures of a seven-level Cascaded H-Bridge Multi-Level idea are applied to shunt and series active filter changeovers to reduce Total Harmonic Distortion and com-pensate for voltage issues.Despite its power quality capacity for common cou-pling,the proposed system can inject the grid’s dynamic power.During voltage interference,it can also provide a piece of delicate burden power.The simulation is carried out with the help of MATLAB/SIMULINK programming,and the results are compared to those of other conventional methods. 展开更多
关键词 Unified power quality conditioner PHOTOVOLTAIC linear predictive phase composition total harmonic distortion
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Linear Complementary Method for Moving Boundary Problems with Phase Transformation 被引量:1
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作者 Deng Kang Shen Min(Shanghai University) Sun Huanchun(Dalian University of Technology) 《Advances in Manufacturing》 SCIE CAS 1998年第3期67-70,共4页
In this paper, the linear complementary method for moving boundary problems with phase transformation is presented, in which a pair of unknown vectors of heat source with phase transforming and the temperature field c... In this paper, the linear complementary method for moving boundary problems with phase transformation is presented, in which a pair of unknown vectors of heat source with phase transforming and the temperature field can be solved exactly, and a large amount of iterative calculations can be avoided. 展开更多
关键词 phase transformation moving boundary problems heat transfer linear complementary equation
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Linearization and analytic solution of fluid dynamics of cell two-phase flow
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作者 范天佑 范蕾 唐志毅 《Journal of Beijing Institute of Technology》 EI CAS 2011年第1期1-3,共3页
Linearized equations of fluid dynamics of cell two phase flow for one dimensional case are proposed. Based on the equations, an analytic solution is derived, in which the frequency of wave is observed. The frequency f... Linearized equations of fluid dynamics of cell two phase flow for one dimensional case are proposed. Based on the equations, an analytic solution is derived, in which the frequency of wave is observed. The frequency formula consists of all important parameters of the fluid dynamics. In our observation, the group velocity and phase velocity of the motion of wave propagation are explicitly exhibited as well. 展开更多
关键词 ell two phase flow fluid dynamics linearIZATION analytic solution
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Joint calibration algorithm for gain-phase and mutual coupling errors in uniform linear array 被引量:9
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作者 Li Weixing Lin Jianzhi +1 位作者 Zhang Yue Chen Zengping 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2016年第4期1065-1073,共9页
The effect of gain-phase perturbations and mutual coupling significantly degrades the performance of digital array radar (DAR). This paper investigates array calibration problems in the scenario where the true locatio... The effect of gain-phase perturbations and mutual coupling significantly degrades the performance of digital array radar (DAR). This paper investigates array calibration problems in the scenario where the true locations of auxiliary sources deviate from nominal values but the angle intervals are known. A practical algorithm is proposed to jointly calibrate gain-phase errors and mutual coupling errors. Firstly, a simplified model of the distortion matrix is developed based on its special structure in uniform linear array (ULA). Then the model is employed to derive the precise locations of the auxiliary sources by one-dimension search. Finally, the least-squares estimation of the distortion matrix is obtained. The algorithm has the potential of achieving considerable improvement in calibration accuracy due to the reduction of unknown parameters. In addition, the algorithm is feasible for practical applications, since it requires only one auxiliary source with the help of rotation platforms. Simulation results demonstrate the validity, robustness and high performance of the proposed algorithm. Experiments were carried out using an S-band DAR test-bed. The results of measured data show that the proposed algorithm is practical and effective in application. (C) 2016 Production and hosting by Elsevier Ltd. on behalf of Chinese Society of Aeronautics and Astronautics. 展开更多
关键词 Calibration accuracy Digital array Gain and phase errors LEAST-SQUARES Mutual coupling Uniform linear array
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Two-Phase Multi Objective Fuzzy Linear Programming Approach for Sustainable Irrigation Planning
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作者 D. G. Regulwar Jyotiba B. Gurav 《Journal of Water Resource and Protection》 2013年第6期642-651,共10页
The objective of the present study is to develop the irrigation planning model and to apply the same in the form of Two-Phase Multi Objective Fuzzy Linear Programming (TPMOFLP) approach for crop planning in command ar... The objective of the present study is to develop the irrigation planning model and to apply the same in the form of Two-Phase Multi Objective Fuzzy Linear Programming (TPMOFLP) approach for crop planning in command area of Jayakwadi Project Stage I, Maharashtra State, India. The development of TPMOFLP model is on the basis of various Linear Programming (LP) models and Multi Objective Fuzzy Linear Programming (MOFLP) models, these models have been applied for maximization of the Net Benefits (NB), Crop production (CP), Employment Generation (EG) and Manure Utilization (MU) respectively. The significant increase in the value of level of satisfaction (λ) has been found from 0.58 to 0.65 by using the TPMOFLP approach as compare to that of MOFLP model based on maxmin approach. The two-phase approach solution provides NB = 1503.56 Million Rupees, CP = 335729.30 Tons, EG = 29.74 Million Man days and MU = 160233.70 Tons respectively. The proposed model will be helpful for the Decision Maker (DM) to take a decision under conflicting situation while planning for different conflicting objectives simultaneously and has potential to find out an integrated irrigation planning with prime consideration for economic, social and environmental issue. 展开更多
关键词 SUSTAINABLE IRRIGATION PLANNING Multi Objective Fuzzy linear PROGRAMMING Maxmin APPROACH TWO-phase APPROACH
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Comparative Study of Linear and Non-Linear Controls of Three-Phase Shunt Active Filters for Improving the Quality of Electrical Energy
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作者 Mamane Adamou Nabil Alkassoum +1 位作者 André Foulani Amadou Seidou Maiga 《Energy and Power Engineering》 2019年第3期149-166,共18页
The aim of this work is to comparatively study two types of control of a three-phase shunt active filter (TSAF) in order to realize a system of depollution of electrical networks so as to improve the quality of electr... The aim of this work is to comparatively study two types of control of a three-phase shunt active filter (TSAF) in order to realize a system of depollution of electrical networks so as to improve the quality of electrical energy. We used two TSA control models which differ in the method of disturbed currents detection, one linear and the other non-linear. The results show that the non-linear control method, although with high calculation blocks, gives more promising results than the linear control method. When connecting a non-linear load (televisions, lamps, variable speed drives, etc.) directly to the public distribution network, the non-linear nature of the load causes the source current to be deformed due to the presence of harmonic currents and voltages. These harmonics thus generate a high reactive power, and therefore considerable electrical losses in the network. One of the solutions to reduce losses on the electricity grid is to incorporate an electronic circuit called a filter into the electricity grid. This work carried out a comparative study of two types of control of a three-phase shunt active filter (TSAF) in order to carry out a system for cleaning up electricity networks in order to improve the quality of electrical energy. We used two TSA control models that differ in the method of detecting disturbed currents, one linear and the other non-linear. The results show that the non-linear control method, although with high calculation blocks, gives better results than the linear control method. 展开更多
关键词 Power QUALITY Active THREE-phase SHUNT Filter NON-linear CONTROL linear CONTROL
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Linear Phase FIR Filter on Measuring 3-D Surface
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作者 WANG Yunshan,YANG Fujun,LI Wei (Shandong University of Technology,Jinan 250061,CHN) 《Semiconductor Photonics and Technology》 CAS 1997年第2期29-34,共6页
An optical technology for 3-D surface measurement is set up.The technology,based on a deformed projected grating pattern which carries the 3-D information of the measured object,can automatically and accurately obtain... An optical technology for 3-D surface measurement is set up.The technology,based on a deformed projected grating pattern which carries the 3-D information of the measured object,can automatically and accurately obtain the phase map of a measured object by using a linear-phase FIR filter.In contrast to the 2-D fast Fourier transform technique,it’s more than fast.Only one image pattern is sufficient for measuring.The phase map can be processed without assigning fringe orders and making distinction between a depression and an elevation.Theoretical analysis and experimental result are presented. 展开更多
关键词 linear-phase FIR FILTER Profilometry Projected GRATING Image 3-D SURFACE
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Modified Single Phase SRF d-q Theory Based Controller for DVR Mitigating Voltage Sag in Case of Nonlinear Load
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作者 Dhiraj N. Katole Manoj B. Daigavane +1 位作者 Snehal P. Gawande Prema M. Daigavane 《Journal of Electromagnetic Analysis and Applications》 2017年第2期22-33,共12页
This paper mainly concentrates on design of improved controller and its implementation based on single phase synchronous reference frame theory (SRFT) for Dynamic Voltage Restorer (DVR) compensating voltage sag partic... This paper mainly concentrates on design of improved controller and its implementation based on single phase synchronous reference frame theory (SRFT) for Dynamic Voltage Restorer (DVR) compensating voltage sag particularly for nonlinear load. In case of single phase distribution line with nonlinear load, the complexity of controller’s design becomes more serious issue. The present single phase and/or three phase theories applicable to DVR shows poor response to restore voltage sag in case of nonlinear load due to presence of harmonics. Hence restoration of voltage sag in single phase nonlinear load connected system has been a serious concern. Therefore, new controller for DVR has been proposed incorporating effective design concept for fundamental component extraction in case of nonlinear load. The single phase SRFT based main controller for DVR works on two separate closed path viz. feed forward path for quick transient response and feedback path for reducing the steady state error. Moreover, pre-sag mitigation strategy of DVR has been adapted through these two aforementioned paths. Complete design of proposed controller is based on phasor analysis. It also consist of proportional integral (PI) controller to reduce the error in the DC-link voltage during compensation time. The controller performance has been verified in MATLAB Simulink for both types (linear and nonlinear) of load. The results obtained indicates that the proposed controller is effective in its performance. 展开更多
关键词 Power Quality Voltage SAG DVR Single phase SRFT BASED CONTROLLER Sinusoidal Pulse WIDTH Modulation Non-linear Load
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Inspection of pipeline girth welds with ultrasonic phased array technique
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作者 Huang Jing(黄晶) Que Peiwen Jin Jianhua 《High Technology Letters》 EI CAS 2005年第3期240-244,共5页
A novel automatic ultrasonic system used for the inspection of pipeline girth welds is developed, in which a linear phased array transducer using electronic scan is adopted. Optimal array parameters are determined bas... A novel automatic ultrasonic system used for the inspection of pipeline girth welds is developed, in which a linear phased array transducer using electronic scan is adopted. Optimal array parameters are determined based on a mathematical model of acoustic field for linear phased army derived from Huygens' principle. The testing method and the system structure are introduced. The experimental results show that the phased array transducer system has the same detectability as that of conventional ultrasonic transducer system, but the system architecture can be simplified greatly, and the testing flexibility and the testing speed can be improved greatly. 展开更多
关键词 linear phased array transducer mathematical model of acoustic field pipeline girth welds defect inspection
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基于分段线性死区补偿的新能源汽车PMSM控制方法研究
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作者 曾德墙 左亮平 戴佳权 《成都工业学院学报》 2026年第1期14-19,共6页
针对新能源汽车驱动系统逆变器死区效应导致的电流及电压波形畸变问题,提出分段线性死区补偿的永磁同步电机(PMSM)控制策略。首先,通过构建dq坐标系电流矢量角计算模型,结合滤波算法,突破依赖硬件电路或复杂参数辨识的传统方法局限,进... 针对新能源汽车驱动系统逆变器死区效应导致的电流及电压波形畸变问题,提出分段线性死区补偿的永磁同步电机(PMSM)控制策略。首先,通过构建dq坐标系电流矢量角计算模型,结合滤波算法,突破依赖硬件电路或复杂参数辨识的传统方法局限,进行相电流极性精准判定。其次,分析死区效应影响,基于精确的电流极性,在电流零点区域,依据补偿角度进行补偿时间分段计算,提出过零点区域分段线性电压补偿新算法。最后,建立MATLAB/Simulink仿真模型进行仿真分析,仿真结果表明,该方法使电流总谐波失真下降了3.67%,基本消除零电流钳位现象,有效改善电流及电压波形畸变问题,提升了新能源汽车PMSM控制性能。 展开更多
关键词 新能源汽车 永磁同步电机 相电流极性 分段线性 死区补偿
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THERMO-RESPONSIVE BLOCK COPOLYMERS BASED ON LINEAR-TYPE POLY(ETHYLENE GLYCOL):TUNABLE LCST WITHIN THE PHYSIOLOGICAL RANGE 被引量:1
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作者 Guo-liang Yue Qian-ling Cui +2 位作者 Yu-xi Zhang Er-jian Wang 吴飞鹏 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2012年第5期770-776,共7页
Therrno-responsive block copolymers poly(ethylene glycol)-block-poly(N-acryloyl-2,2-dimethyl-1,3-oxazolidine), PEG-b-PADMO, based on linear PEG were prepared via a versatile reversible addition-fragmentation chain... Therrno-responsive block copolymers poly(ethylene glycol)-block-poly(N-acryloyl-2,2-dimethyl-1,3-oxazolidine), PEG-b-PADMO, based on linear PEG were prepared via a versatile reversible addition-fragmentation chain transfer (RAFT) polymerization, PEG22 (Mw = 1000) was used as the hydrophilic component, whose dehydration was the main driving force for the phase transition of these copolymers, as demonstrated by the tH-NMR spectra. Their lower critical solution temperatures (LCSTs) could be tuned in the range of 20℃ to 35℃, by adjusting the degree of polymerization (DP) of PADMO between 14-27. Furthermore, a sharp phase transition at ca. 33℃, close to the physiological temperature with minimal hysteresis, was observed for the PEGzz-b-PADMO14 copolymer. Moreover, excellent reversibility and reproducibility were displayed for the same copolymer over 10 cycles of repeated temperature change between 25℃ (below the LCST) and 40℃ (above the LCST). 展开更多
关键词 THERMO-RESPONSIVE Block copolymers linear PEG phase transitions.
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On-line SPE/LC-LIT-MS法快速测定全血和肝组织中的利多卡因及其代谢物
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作者 卢敏萍 莫旖 +4 位作者 何日梅 黄克建 刘晓锋 杨宁 乔文涛 《化学研究与应用》 北大核心 2026年第1期228-233,共6页
基于在线固相萃取(on-line SPE)前处理技术,建立了一种快速测定全血和肝组织样品中利多卡因(LDC)及其代谢物单乙基甘氨酰二甲基苯胺(MEGX)、甘氨酰二甲基苯胺(GX)的液相色谱-线性离子阱质谱(LC-LIT-MS)分析方法。用乙腈沉淀样品中的蛋白... 基于在线固相萃取(on-line SPE)前处理技术,建立了一种快速测定全血和肝组织样品中利多卡因(LDC)及其代谢物单乙基甘氨酰二甲基苯胺(MEGX)、甘氨酰二甲基苯胺(GX)的液相色谱-线性离子阱质谱(LC-LIT-MS)分析方法。用乙腈沉淀样品中的蛋白,再经稀释、离心、过滤后即可进样。采用Waters Oasis®HLB在线SPE柱对样品进行快速富集纯化,结束后,通过阀切换将样品转移至Syncronis C8分析柱进行梯度洗脱,流动相为均含0.1%甲酸(V/V)的0.01 mol·L^(-1)乙酸铵溶液(A)和甲醇(B),最后使用电喷雾电离正离子源(ESI^(+)),在多反应监测(MRM)模式下进行测定,对利多卡因及其代谢物实现定性筛查与定量分析。在考察的浓度范围内,三种分析物均获得了良好的线性关系,相关系数为0.998 3~0.999 6,全血样品的检出限为(0.1~2.0)ng·mL^(−1),肝组织样品的检出限为(0.1~2.0)ng·g^(-1),3个添加水平的回收率为94.0~108.6%,相对标准偏差为0.1~5.8%(n=6)。该方法避免了繁琐的前处理过程,简单灵敏,结果准确可靠,适用于全血和肝组织样品中利多卡因及其代谢物的快速测定。 展开更多
关键词 在线固相萃取 LC-LIT-MS法 利多卡因 代谢物 全血 肝组织
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