Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass majorly focused on cellulose and hemicellulose restricts the economic and environment...Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass majorly focused on cellulose and hemicellulose restricts the economic and environmental feasibilities. To cope with this issue, we proposed an integrated process of co-producing 1,6-hexanediol(1,6-HDO) with tetrahydrofuran and adipic acid from biomass, referred to as Strategy A. To compare the impacts of lignin upgrading and feedstock, Strategy B, which co-produces tetrahydrofuran alone, and Strategy C, which is the traditional route to produce 1,6-HDO from fossil fuels, were used. Heat networks are also designed to reduce operating costs and indirect carbon emissions due to energy consumption, saving 87% and 83% of the heat and cooling requirements, respectively, in Strategy A. The market competitiveness of Strategy A was evaluated by determining the minimum selling price through techno-economic analysis, and sustainability was thoroughly investigated by quantifying the environmental impacts through both midpoint and endpoint life-cycle assessments(LCAs).Strategy A was found to be the most favorable both economically(USRDSCHARDOLLAR3,402/ton) and environmentally(-26.9 kg CO_(2)eq.). This indicates that lignin valorization is not only economically but also environmentally preferred. Finally, changes in economic and environmental feasibilities depending on economic, process, and environmental parameters were investigated using sensitivity and uncertainty analyses. The results of these analyses provide valuable insight into bio-based chemical production.展开更多
Lignin,an energy-rich and adaptable polymer comprising phenylpropanoid monomers utilized by plants for structural reinforcement,water conveyance,and defense mechanisms,ranks as the planet's second most prevalent b...Lignin,an energy-rich and adaptable polymer comprising phenylpropanoid monomers utilized by plants for structural reinforcement,water conveyance,and defense mechanisms,ranks as the planet's second most prevalent biopolymer,after cellulose.Despite its prevalence,lignin is frequently underused in the process of converting biomass into fuels and chemicals.Instead,it is commonly incinerated for industrial heat due to its intricate composition and resistance to decomposition,presenting obstacles for targeted valorization.In contrast to chemical catalysts,biological enzymes show promise not only in selectively converting lignin components but also in seamlessly integrating into cellular structures,offering biocatalysis as a potentially efficient pathway for lignin enhancement.This review comprehensively summarizes cutting-edge biostrategies,ligninolytic enzymes,metabolic pathways,and lignin-degrading strains or consortia involved in lignin degradation,while critically evaluating the underlying mechanisms.Metabolic and genetic engineering play crucial roles in redirecting lignin and its derivatives towards metabolic pathways like the tricarboxylic acid cycle,opening up novel avenues for its valorization.Recent advancements in lignin valorization are scrutinized,highlighting key challenges and promising solutions.Furthermore,the review underscores the importance of innovative approaches,such as leveraging digital systems and synthetic biology,to unlock the commercial potential of lignin-derived raw materials as sustainable feedstocks.Artificial intelligence-driven technologies offer promise in overcoming current challenges and driving widespread adoption of lignin valorization,presenting an alternative to sugar-based feedstocks for bio-based manufacturing in the future.The utilization of available lignin residue for synthesis of high-value chemicals or energy,even alternative food,addresses various crises looming in the food-energy-water nexus.展开更多
基金Material Parts Technology Development Program (20017461, Development and Performance Improvement of Air Operated Valve for 105 MPa Hydrogen Charging Station) funded by the Ministry of Trade,Industry and Energy(MOTIE, Republic of Korea)Korea Evaluation Institute of Industrial Technology (KEIT, Republic of Korea)+1 种基金financial support from the Korea Institute of Energy Technology Evaluation and Planning (KETEP)Ministry of Trade,Industry&Energy (MOTIE) of the Republic of Korea(RS-2024-00419764)。
文摘Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass majorly focused on cellulose and hemicellulose restricts the economic and environmental feasibilities. To cope with this issue, we proposed an integrated process of co-producing 1,6-hexanediol(1,6-HDO) with tetrahydrofuran and adipic acid from biomass, referred to as Strategy A. To compare the impacts of lignin upgrading and feedstock, Strategy B, which co-produces tetrahydrofuran alone, and Strategy C, which is the traditional route to produce 1,6-HDO from fossil fuels, were used. Heat networks are also designed to reduce operating costs and indirect carbon emissions due to energy consumption, saving 87% and 83% of the heat and cooling requirements, respectively, in Strategy A. The market competitiveness of Strategy A was evaluated by determining the minimum selling price through techno-economic analysis, and sustainability was thoroughly investigated by quantifying the environmental impacts through both midpoint and endpoint life-cycle assessments(LCAs).Strategy A was found to be the most favorable both economically(USRDSCHARDOLLAR3,402/ton) and environmentally(-26.9 kg CO_(2)eq.). This indicates that lignin valorization is not only economically but also environmentally preferred. Finally, changes in economic and environmental feasibilities depending on economic, process, and environmental parameters were investigated using sensitivity and uncertainty analyses. The results of these analyses provide valuable insight into bio-based chemical production.
基金supported by the National Key R&D program of China(2023YFD1600502)Strategic Priority Research Program of Chinese Academy of Sciences(XDC0110304)。
文摘Lignin,an energy-rich and adaptable polymer comprising phenylpropanoid monomers utilized by plants for structural reinforcement,water conveyance,and defense mechanisms,ranks as the planet's second most prevalent biopolymer,after cellulose.Despite its prevalence,lignin is frequently underused in the process of converting biomass into fuels and chemicals.Instead,it is commonly incinerated for industrial heat due to its intricate composition and resistance to decomposition,presenting obstacles for targeted valorization.In contrast to chemical catalysts,biological enzymes show promise not only in selectively converting lignin components but also in seamlessly integrating into cellular structures,offering biocatalysis as a potentially efficient pathway for lignin enhancement.This review comprehensively summarizes cutting-edge biostrategies,ligninolytic enzymes,metabolic pathways,and lignin-degrading strains or consortia involved in lignin degradation,while critically evaluating the underlying mechanisms.Metabolic and genetic engineering play crucial roles in redirecting lignin and its derivatives towards metabolic pathways like the tricarboxylic acid cycle,opening up novel avenues for its valorization.Recent advancements in lignin valorization are scrutinized,highlighting key challenges and promising solutions.Furthermore,the review underscores the importance of innovative approaches,such as leveraging digital systems and synthetic biology,to unlock the commercial potential of lignin-derived raw materials as sustainable feedstocks.Artificial intelligence-driven technologies offer promise in overcoming current challenges and driving widespread adoption of lignin valorization,presenting an alternative to sugar-based feedstocks for bio-based manufacturing in the future.The utilization of available lignin residue for synthesis of high-value chemicals or energy,even alternative food,addresses various crises looming in the food-energy-water nexus.
