The high mortality rates of colon and rectal tumors have put forward an urgent need for rapid, sensitive, and accurate diagnosis. The polarization imaging technology, with the advantages of noninvasiveness, noncontact...The high mortality rates of colon and rectal tumors have put forward an urgent need for rapid, sensitive, and accurate diagnosis. The polarization imaging technology, with the advantages of noninvasiveness, noncontact, quantification, rapidity, and high sensitivity, is expected to be used for auxiliary diagnosis of colorectal cancer. Herein, the differences in colorectal tissues of four pathological types were studied using this powerful technology. Polarized light imaging combined with the Mueller matrix decomposition (MMPD) method was applied to extract structural features that may be related to colorectal tumors. It demonstrated that parameters δ and θ could reflect the structural differences of colorectal tumors. Preliminary simulated experiment results revealed that the parameter δ was related to the fiber density, and the parameter θ was related to the fiber angle. Then Tamura image texture analysis was used to quantitatively describe tissues of different pathological types, and the results showed that the coarseness, contrast, directionality, and roughness of the four groups were statistically different. Texture analysis based on the quantitative data of the four dimensions could be applied for the identification of benign and malignant colorectal tumors.展开更多
https://www.sciencedirect.com/journal/energy-and-buildings/vol/344/suppl/C Volume 344,1 October 2025(1)[OA](1)Energy impact of integrative lighting:as ystematic literature review by Marziyeh Taghizadeh,Niko Gentile,Pi...https://www.sciencedirect.com/journal/energy-and-buildings/vol/344/suppl/C Volume 344,1 October 2025(1)[OA](1)Energy impact of integrative lighting:as ystematic literature review by Marziyeh Taghizadeh,Niko Gentile,Pimkamol Mattsson,et al,Article 115920 Abstract:Integrative lighting promoting circadian health hasr ecently gained attention due to the increasing awareness of nonvisual effects of light and advancements in lighting technology.However,reaching both visual and non-visual circadian targets inb uildings may be challenging when considering energy use.展开更多
With the development of sound and light technology, they are increasingly being applied to art exhibitions and creations, and even become an indispensable part of the work of art. Installation art prints are more orna...With the development of sound and light technology, they are increasingly being applied to art exhibitions and creations, and even become an indispensable part of the work of art. Installation art prints are more ornamental interesting, appealing and shocking when being promoted by sound and light technology, but also providing more ideas and methods for creators. The creators but also should pay attention to rational use of sound and light technology to achieve better performance results.展开更多
Background: The skin serves as the first line of defense for the human body. Direct sunlight contains damaging radiations that can speed up the ageing process of the skin, resulting in wrinkles, leathery skin, dark pa...Background: The skin serves as the first line of defense for the human body. Direct sunlight contains damaging radiations that can speed up the ageing process of the skin, resulting in wrinkles, leathery skin, dark patches, and solar elastosis. Objectives: To evaluate the effect of multiple solar irradiation related factors at the protein level in human dermal fibroblast (HDF). The overall effect of individual solar irradiations such as Infrared A (IRA), blue light (BL), UVA, and UVB on HDF cells and the extent of molecular level aberrations to be assessed and compared against each. Methods: Label-free quantitative proteomics (MS/MS) approach has been adopted in this study to observe the protein level changes induced in the HDF cells through various exposures of full light sources. Following that, downstream insilico analysis has been carried out. Results: In this study, it is demonstrated all the four different solar irradiations significantly contribute to the molecular degeneration of skin cells through various mechanisms. This study confirms that BL down-regulates DNA repair proteins and the skin cells-HDF stimulate the histone proteins as a response mechanism to maintain the chromosomal integrity. Conclusions: The proteomics experiment carried out in the current study intends to support the future sun care products based on full light protection technology that can be custom designed to provide complete protection from the solar radiation. Similar technology could enhance the further investigations for deeper understanding of induction, mode of action, and prevention of skin damage from extensive solar irradiation.展开更多
Objective:To develop and optimize intense pulsed light(IPL)technology for the treatment of blepharitis-associated dry eye disease and to evaluate its biomedical effects on meibomian gland function and corneal epitheli...Objective:To develop and optimize intense pulsed light(IPL)technology for the treatment of blepharitis-associated dry eye disease and to evaluate its biomedical effects on meibomian gland function and corneal epithelial repair.Methods:The affected eyes of 90 patients with blepharitis-associated dry eye disease admitted to our hospital were selected,and the optimal parameters of enhanced pulsed light technology for dry eye syndrome were selected by L_(9)(3^(4))orthogonal experimental design with pulse width,pulse delay and energy gradient as the influencing factors,and the meibomian gland function was used as the evaluation index.The effect on meibomian gland f unction and corneal epithelial repair in patients with dry eye inflammation of the palpebral margin was observed.Results:The analysis of variance(ANOVA)results for the response surface methodology experiment demonstrated that the established model(R1=+0.92+0.38×energy gradient-0.33×pulse duration-0.10×pulse delay+0.65×energy gradient×pulse duration+1.30×energy gradient×pulse delay+0.100×pulse duration×pulse delay+1.37×energy gradient^(2)+0.065×pulse duration^(2)-0.58×pulse delay^(2))showed statistical significance(P<0.05),and the lack-of-fit term was non-significant(P>0.05),indicating that high reliability and successful modeling.The optimal parameters of the three factors appeared in the energy gradient pulse width of 14 J,10.82 ms,and pulse delay of 40.14 ms.After optimization with reference to the above parameters,the difference in meibomian gland function grade in 45 patients was significantly higher than that of the patients before optimization(P<0.05).Conclusion:The optimized IPL technology demonstrotes a significant improvement in blepharitis-associated dry eye disease,which can improve meibomian gland function,but still cannot promote corneal epithelial repair,so other treatment regimens can be considered.展开更多
Making full-color active matrix display based on quantum dot light emitting diodes(AM-QLEDs) via ink-jet printing is attractive in display industry due to QLEDs' wide color gamut and their potential manufacturing ...Making full-color active matrix display based on quantum dot light emitting diodes(AM-QLEDs) via ink-jet printing is attractive in display industry due to QLEDs' wide color gamut and their potential manufacturing advantages of large screen size and low cost. The challenges for realizing AM-QLED display are how to achieve high quality films through ink-jet printing, multi-color patterning, electroluminescence(EL) color purity, and high efficiency. Herein, a 2-inch diagonal full-color AM-QLEDs display with pixel density of 120 pixels per inch(PPI) fabricated by ink-jet printing technique is presented. Driven by a metal oxide TFT(MOTFT) back-panel, the display exhibits a maximum brightness of 400 cd m.2, and a color gamut of 109%(NTSC 1931). The red, green, and blue(RGB) monochrome QLEDs passive matrix panels fabricated by ink-jet printing technique have a current efficiency(CE) of 2.5, 13.9, and 0.30 cd A.1, respectively. To the best of our knowledge, the efficiencies are the highest among passive matrix QLEDs panels made by ink-jet printing technique. The ink-jet printed QDs films show good thickness uniformity due to high viscosity and low volatility of the printable inks, and no cross-contamination between adjacent pixels resulting from the hydrophobic pixel defining layer.展开更多
A state-owned enterprise grasps new opportunities In a huge dome immersed in blue laser lights,people experience a breathtaking race along glowing glass rails,accompanied by adrenaline-pumping music with3Dgraphics fas...A state-owned enterprise grasps new opportunities In a huge dome immersed in blue laser lights,people experience a breathtaking race along glowing glass rails,accompanied by adrenaline-pumping music with3Dgraphics fashingpasttheireyes.展开更多
文摘The high mortality rates of colon and rectal tumors have put forward an urgent need for rapid, sensitive, and accurate diagnosis. The polarization imaging technology, with the advantages of noninvasiveness, noncontact, quantification, rapidity, and high sensitivity, is expected to be used for auxiliary diagnosis of colorectal cancer. Herein, the differences in colorectal tissues of four pathological types were studied using this powerful technology. Polarized light imaging combined with the Mueller matrix decomposition (MMPD) method was applied to extract structural features that may be related to colorectal tumors. It demonstrated that parameters δ and θ could reflect the structural differences of colorectal tumors. Preliminary simulated experiment results revealed that the parameter δ was related to the fiber density, and the parameter θ was related to the fiber angle. Then Tamura image texture analysis was used to quantitatively describe tissues of different pathological types, and the results showed that the coarseness, contrast, directionality, and roughness of the four groups were statistically different. Texture analysis based on the quantitative data of the four dimensions could be applied for the identification of benign and malignant colorectal tumors.
文摘https://www.sciencedirect.com/journal/energy-and-buildings/vol/344/suppl/C Volume 344,1 October 2025(1)[OA](1)Energy impact of integrative lighting:as ystematic literature review by Marziyeh Taghizadeh,Niko Gentile,Pimkamol Mattsson,et al,Article 115920 Abstract:Integrative lighting promoting circadian health hasr ecently gained attention due to the increasing awareness of nonvisual effects of light and advancements in lighting technology.However,reaching both visual and non-visual circadian targets inb uildings may be challenging when considering energy use.
文摘With the development of sound and light technology, they are increasingly being applied to art exhibitions and creations, and even become an indispensable part of the work of art. Installation art prints are more ornamental interesting, appealing and shocking when being promoted by sound and light technology, but also providing more ideas and methods for creators. The creators but also should pay attention to rational use of sound and light technology to achieve better performance results.
文摘Background: The skin serves as the first line of defense for the human body. Direct sunlight contains damaging radiations that can speed up the ageing process of the skin, resulting in wrinkles, leathery skin, dark patches, and solar elastosis. Objectives: To evaluate the effect of multiple solar irradiation related factors at the protein level in human dermal fibroblast (HDF). The overall effect of individual solar irradiations such as Infrared A (IRA), blue light (BL), UVA, and UVB on HDF cells and the extent of molecular level aberrations to be assessed and compared against each. Methods: Label-free quantitative proteomics (MS/MS) approach has been adopted in this study to observe the protein level changes induced in the HDF cells through various exposures of full light sources. Following that, downstream insilico analysis has been carried out. Results: In this study, it is demonstrated all the four different solar irradiations significantly contribute to the molecular degeneration of skin cells through various mechanisms. This study confirms that BL down-regulates DNA repair proteins and the skin cells-HDF stimulate the histone proteins as a response mechanism to maintain the chromosomal integrity. Conclusions: The proteomics experiment carried out in the current study intends to support the future sun care products based on full light protection technology that can be custom designed to provide complete protection from the solar radiation. Similar technology could enhance the further investigations for deeper understanding of induction, mode of action, and prevention of skin damage from extensive solar irradiation.
文摘Objective:To develop and optimize intense pulsed light(IPL)technology for the treatment of blepharitis-associated dry eye disease and to evaluate its biomedical effects on meibomian gland function and corneal epithelial repair.Methods:The affected eyes of 90 patients with blepharitis-associated dry eye disease admitted to our hospital were selected,and the optimal parameters of enhanced pulsed light technology for dry eye syndrome were selected by L_(9)(3^(4))orthogonal experimental design with pulse width,pulse delay and energy gradient as the influencing factors,and the meibomian gland function was used as the evaluation index.The effect on meibomian gland f unction and corneal epithelial repair in patients with dry eye inflammation of the palpebral margin was observed.Results:The analysis of variance(ANOVA)results for the response surface methodology experiment demonstrated that the established model(R1=+0.92+0.38×energy gradient-0.33×pulse duration-0.10×pulse delay+0.65×energy gradient×pulse duration+1.30×energy gradient×pulse delay+0.100×pulse duration×pulse delay+1.37×energy gradient^(2)+0.065×pulse duration^(2)-0.58×pulse delay^(2))showed statistical significance(P<0.05),and the lack-of-fit term was non-significant(P>0.05),indicating that high reliability and successful modeling.The optimal parameters of the three factors appeared in the energy gradient pulse width of 14 J,10.82 ms,and pulse delay of 40.14 ms.After optimization with reference to the above parameters,the difference in meibomian gland function grade in 45 patients was significantly higher than that of the patients before optimization(P<0.05).Conclusion:The optimized IPL technology demonstrotes a significant improvement in blepharitis-associated dry eye disease,which can improve meibomian gland function,but still cannot promote corneal epithelial repair,so other treatment regimens can be considered.
基金supported by the National Key Basic Research and Development Program of China (2015CB655004)the National Natural Science Foundation of China (U1601651, 51521002, U1301243, 61574061)the Educational Commission of Guangdong Province (2015B090914003, 2014KZDXM012)
文摘Making full-color active matrix display based on quantum dot light emitting diodes(AM-QLEDs) via ink-jet printing is attractive in display industry due to QLEDs' wide color gamut and their potential manufacturing advantages of large screen size and low cost. The challenges for realizing AM-QLED display are how to achieve high quality films through ink-jet printing, multi-color patterning, electroluminescence(EL) color purity, and high efficiency. Herein, a 2-inch diagonal full-color AM-QLEDs display with pixel density of 120 pixels per inch(PPI) fabricated by ink-jet printing technique is presented. Driven by a metal oxide TFT(MOTFT) back-panel, the display exhibits a maximum brightness of 400 cd m.2, and a color gamut of 109%(NTSC 1931). The red, green, and blue(RGB) monochrome QLEDs passive matrix panels fabricated by ink-jet printing technique have a current efficiency(CE) of 2.5, 13.9, and 0.30 cd A.1, respectively. To the best of our knowledge, the efficiencies are the highest among passive matrix QLEDs panels made by ink-jet printing technique. The ink-jet printed QDs films show good thickness uniformity due to high viscosity and low volatility of the printable inks, and no cross-contamination between adjacent pixels resulting from the hydrophobic pixel defining layer.
文摘A state-owned enterprise grasps new opportunities In a huge dome immersed in blue laser lights,people experience a breathtaking race along glowing glass rails,accompanied by adrenaline-pumping music with3Dgraphics fashingpasttheireyes.
