INTRODUCTION B-type natriuretic peptide （BNP） is a 32- amino acid polypeptide secreted by ventricular myocytes during period of increased ventricu- lar stretch and wall tension. It is believed that the peptide play...INTRODUCTION B-type natriuretic peptide （BNP） is a 32- amino acid polypeptide secreted by ventricular myocytes during period of increased ventricu- lar stretch and wall tension. It is believed that the peptide plays an important role in the reg- ulation of blood pressure, blood volume, and sodium balance. Because in vitro studies have reported that natriuretic peptides are directly released from cardiomyocytes in response to myocardial ischemia , it has been proposed that their circulating levels are relevant to sub- sequent risk of cardiovascular diseases （CVDs） other than heart failure.展开更多
文摘INTRODUCTION B-type natriuretic peptide （BNP） is a 32- amino acid polypeptide secreted by ventricular myocytes during period of increased ventricu- lar stretch and wall tension. It is believed that the peptide plays an important role in the reg- ulation of blood pressure, blood volume, and sodium balance. Because in vitro studies have reported that natriuretic peptides are directly released from cardiomyocytes in response to myocardial ischemia , it has been proposed that their circulating levels are relevant to sub- sequent risk of cardiovascular diseases （CVDs） other than heart failure.
