1 A study shows that music lessons obviously enhance children's cognitive abilities,including short⁃term memory and planning,which lead to improving academic performance.The research is the first large⁃scale and l...1 A study shows that music lessons obviously enhance children's cognitive abilities,including short⁃term memory and planning,which lead to improving academic performance.The research is the first large⁃scale and long⁃term study to be adapted into the regular school curriculum.Visual arts lessons were also found to significantly improve children's visual memory.展开更多
Rainfall-induced landslides are often highly destructive.Reviewing and analyzing the causes,processes,impacts,and deficiencies in emergency response is critical for improving disaster prevention and management.From th...Rainfall-induced landslides are often highly destructive.Reviewing and analyzing the causes,processes,impacts,and deficiencies in emergency response is critical for improving disaster prevention and management.From the night of July 21 to the morning of July 22,2024,the Kencho Shacha Gozdi Village in Gezei Gofa,Southern Nations,Nationalities,and Peoples'Region,Ethiopia,suffered heavy rainfall that triggered two landslides.By July25,this event had claimed at least 257 lives.This study presents a detailed characterization of the landslides using multi-source data.By analyzing the landslide disaster process,this study summarizes key lessons and provides suggestions for preventing rainfall-induced geological hazards.The results indicate that rainfall has the greatest impact on the occurrence of landslides,while lithology and human activities have promoted and strengthened the landslide disaster.Despite the active disaster response in the local area,many problems were still exposed in the emergency response work.This analysis offers valuable insights for mitigating rainfall-induced geological hazards and enhancing emergency response capabilities.展开更多
African ambassadors reflect on Nujiang’s poverty reduction strategies.Diplomats,government officials,and experts from 34 countries and regions shared experiences in poverty reduction during the 2025 International For...African ambassadors reflect on Nujiang’s poverty reduction strategies.Diplomats,government officials,and experts from 34 countries and regions shared experiences in poverty reduction during the 2025 International Forum on Poverty Governance and Global Development held on 29 March in Lushui City,Nujiang Lisu Autonomous Prefecture,Yunnan Province.展开更多
Annyeong-haseyo!What pops into your mind when you hear this familiar Korean greeting?K-Dramas?K-Pop idols?The dazzling lights of Seoul?Or advanced microsurgery?What if I told you I experienced all things Korean—strol...Annyeong-haseyo!What pops into your mind when you hear this familiar Korean greeting?K-Dramas?K-Pop idols?The dazzling lights of Seoul?Or advanced microsurgery?What if I told you I experienced all things Korean—strolling the streets in a hanbok,savoring kimchi,and sipping soju—not in South Korea,but in China?展开更多
On March 28,2025,a catastrophic M 7.9 earthquake shook central Myanmar,causing extensive damage to buildings,significant casualties,and substantial economic loss,making it one of the most severe natural disasters Myan...On March 28,2025,a catastrophic M 7.9 earthquake shook central Myanmar,causing extensive damage to buildings,significant casualties,and substantial economic loss,making it one of the most severe natural disasters Myanmar has faced in recent years.During an on-site investigation that lasted two weeks,widely spreading liquefaction phenomena and associated damage to buildings and other facilities were investigated in 16 villages or districts in the seismic zones,involving hundreds of residential houses,two large bridges,underground storage tanks,etc.Ground fissures generated by liquefaction tore apart houses,which contributed to a significant impact on house damage.The loss of ground bearing capacity is another impact of liquefaction with regard to structural damage,causing the subsidence and tilting of houses.Several consequences of liquefaction were identified,such as lateral spreading,which demolishes houses and causes casualties,as well as damage to two large bridges as a result of lateral spreading.The cases of liquefaction following the Myanmar earthquake reported on herein provide data and lessons for future seismic desigs to help prevent such disasters in Southeast Asia.Through analyzing the phenomena and characteristics of soil liquefaction,the methods and techniques for liquefaction hazard mitigation in other countries also can be improved.展开更多
The provision of water and sanitation services is a key challenge worldwide.The size,complexity,and critical nature of the water and wastewater infrastructure providing such services make the planning and management o...The provision of water and sanitation services is a key challenge worldwide.The size,complexity,and critical nature of the water and wastewater infrastructure providing such services make the planning and management of these systems extremely difficult.Following the digital revolution in many areas of our lives,the water sector has begun to benefit from digital transformation.Effective utilization of remotely sensed weather and soil moisture data for more efficient irrigation(i.e.,for food production),better detection of anomalies and faults in pipe networks using artificial intelligence,the use of nature-inspired optimization to improve the management and planning of systems,and greater use of digital twins and robotics all exhibit great potential to change and improve the ways in which complex water systems are managed.However,there are additional risks associated with these developments,including—but not limited to—cybersecurity,incorrect use,and overconfidence in the capability and accuracy of digital solutions and automation.This paper identifies key advances in digital technology that have found application in the water sector,and applies forensic engineering principles to failures that have been experienced in industries further ahead with automation and digital transformation.By iden-tifying what went wrong with new digital technologies that might have contributed to high-profile acci-dents in the car and aircraft industries(e.g.,Tesla self-driving cars and the Boeing 737 MAX),it is possible to identify similar risks in the water sector,learn from them,and prevent future failures.The key findings show that:①Automation will require“humans in the loop”;②human operators must be fully aware of the technology and trained to use it;③fallback manual intervention should be available in case of tech-nology malfunctioning;④while redundant sensors may be costly,they reduce the risks due to erroneous sensor readings;⑤cybersecurity risks must be considered;and⑥ethics issues have to be considered,given the increasing automation and interconnectedness of water systems.These findings also point to major research areas related to digital transformation in the water sector.展开更多
Retinal ganglions cells （RGCs） are responsible for propagating electrochemical information from the eye to the brain along their axons which make up the optic nerve. The loss of RGCs is characteristic in several con...Retinal ganglions cells （RGCs） are responsible for propagating electrochemical information from the eye to the brain along their axons which make up the optic nerve. The loss of RGCs is characteristic in several conditions such as glaucoma and trau- matic optic neuropathy and leads to visual loss and blindness. While no therapy exists to directly treat RGCs, the use of bone marrow-derived mesenchymal stem cells （BMSCs） has shown promise in eliciting significant RGC neuroprotection.展开更多
On April 14,2010,an earthquake reaching Richter scale 7.1 struck Jiegu Town of Yushu,a mountain rescue operation promptly launched. All injurers had a direct assess to take medical care,and were immediately rescued an...On April 14,2010,an earthquake reaching Richter scale 7.1 struck Jiegu Town of Yushu,a mountain rescue operation promptly launched. All injurers had a direct assess to take medical care,and were immediately rescued and rapidly evacuated by air to Xining and Golmud at lower altitudes and admitted to advanced hospitals. Almost all of the injurers have been completely recovered. Yushu Earthquake was one of the highest earthquakes in the world,with a high incidence of acute altitude illness,which was observed in about 80 % of the lowland rescuers at an altitude of 4 000 m."Rescue the rescuers"became the major task of Qinghai-Tibetan rescue teams,all the severe patients were rapidly descended to Xining and treated promptly and effectively. The outcome was excellent,all patients survived. After the earthquake,it is a long and arduous task to reconstruct what has been destroyed. Medical teams continue to work in the Yushu Earthquake area because about 30 000 workers and carders are now here for rebuilding the earthquake center. Thus the prevention and treatment of altitude illness are still critical tasks for medical teams. Although all the fights are successful,there are more experiences and lessons we have learned from the medical mountain rescue during the earthquake and the reconstruction,and reports here are to sum up our experiences from the medical mountain rescue operation in Yushu Earthquake and draw the lessons that we should learn. With the increasing of earthquake probability occurring in the Qinghai-Tibetan Plateau,we also should prepare against earthquake disasters and for further rescue training in the high mountains.展开更多
Exercise is a potent force of nature with significant potential for extending longevity and boosting physical fitness. It is also be- ing increasingly used as a prophylactic and curative measure for various physical a...Exercise is a potent force of nature with significant potential for extending longevity and boosting physical fitness. It is also be- ing increasingly used as a prophylactic and curative measure for various physical ailments, such as cardiovascular diseases and diabetes.展开更多
The intestinal microbiome has emerged as an important component involved in various diseases.Therefore,the interest in understanding the factors shaping its composition is growing.The gut microbiome,often defined as a...The intestinal microbiome has emerged as an important component involved in various diseases.Therefore,the interest in understanding the factors shaping its composition is growing.The gut microbiome,often defined as a complex trait,contains diverse components and its properties are determined by a combination of external and internal effects.Although much effort has been invested so far,it is still difficult to evaluate the extent to which human genetics shape the composition of the gut microbiota.However,in mouse studies,where the environmental factors are better controlled,the effect of the genetic background was significant.The purpose of this paper is to provide a current assessment of the role of human host genetics in shaping the gut microbiome composition.Despite the inconsistency of the reported results,it can be estimated that the genetic factor affects a portion of the microbiome.However,this effect is currently lower than the initial estimates,and it is difficult to separate the genetic influence from the environmental effect.Additionally,despite the differences between the microbial composition of humans and mice,results from mouse models can strengthen our knowledge of host genetics underlying the human gut microbial variation.展开更多
English teaching is an integral part of education,which shoulders the responsibility of rendering rudimentary knowledge of English to the students,providing the students with the listening,speaking,reading and writing...English teaching is an integral part of education,which shoulders the responsibility of rendering rudimentary knowledge of English to the students,providing the students with the listening,speaking,reading and writing ability,as well as the obligation of carrying out ideological education and cultivating their noble and healthy sentiment.In teaching,the teachers should pay special attention to the students' thirst for English learning and give full play to their initiative,which demands enough lead-in preparation before class.The lead-in of new lessons bears a direct impact on the quality of the classroom teaching.This thesis will make an analysis of this problem in two aspects.展开更多
This paper describes some special features of the Wenchuan earthquake that affected dam safety. Damage and performance of dams, primarily for four dams over 100 m high located in the affected earthquake area, are brie...This paper describes some special features of the Wenchuan earthquake that affected dam safety. Damage and performance of dams, primarily for four dams over 100 m high located in the affected earthquake area, are briefly described. Lessons learned related to dam safety from this devastating earthquake are preliminarily drawn. As the seismic safety of high dams during strong earthquakes has gained more attention around the world, some critical issues related to dam construction in China are considered and extensively discussed. Questions such as ＂Why is dam construction necessary in earthquake prone countries such as China？＂, ＂Can we accurately evaluate the seismic safety of high dams in China？＂, ＂Did reservoir impounding of the Zipingpu and Three Gorges Projects trigger the Wenchuan Earthquake in some way？＂ and ＂What is the strategic priority of dam safety for large dams in China？＂ are discussed. Finally, the corresponding tactics with response to the challenge are suggested and recent preliminary progress mainly achieved in IWHR is briefly introduced.展开更多
Traumatic brain injury （TBI） is a mechanical injury to brain tissue that leads to an impairment of function and a broad spectrum of symptoms and disabilities; often, it is followed by diffuse axonal injury, which ca...Traumatic brain injury （TBI） is a mechanical injury to brain tissue that leads to an impairment of function and a broad spectrum of symptoms and disabilities; often, it is followed by diffuse axonal injury, which causes denaturation of the white matter and axon retraction, leaving patients with severe brain damage or even in a persistent vegetative state.展开更多
The agri and food industry is a major industrial sector in Denmark. Compared to other countries on a similar level of economic development Denmark has an extremely important agriculture and agribusiness sector. Danish...The agri and food industry is a major industrial sector in Denmark. Compared to other countries on a similar level of economic development Denmark has an extremely important agriculture and agribusiness sector. Danish agri and food cooperatives seem to have been successful in obtaining international competitiveness. The transformation and the structural development of the cooperative sector have more or less been completed. The development of the industrial structure among Danish agricultural cooperatives has been very rapid during the latest decades. Through mergers and acquisitions the number of firms has fallen dramatically, and the result has been increasing concentration ratios in almost all groups of the food industry. Structural development, concentration and globalization in recent decades have resulted in agri and food companies now being among the largest in Europe. To a large extent, agriculture all over the world faces similar problems and challenges. For this reason, it is essential that know-how, experiences and lessons can be transferred and adopted by agriculture in other countries around the world. In many ways, the experience and the success behind Danish agriculture and agribusiness can be transferred to other countries. However, profound studies of specific needs and conditions are necessary.展开更多
<strong>Background:</strong> Coronavirus-19 (COVID-19) dramatically impacted institutions of higher education. The effect was acute in the practice disciplines such as medicine, medical laboratory science,...<strong>Background:</strong> Coronavirus-19 (COVID-19) dramatically impacted institutions of higher education. The effect was acute in the practice disciplines such as medicine, medical laboratory science, and nursing. The purpose is to describe how an interdisciplinary team, led by nursing faculty, adapted to the changes driven by COVID-19 and the lessons that were learned for nursing and other disciplines in higher education. <strong>Method:</strong> The interdisciplinary group created a comprehensive list which captured the impact of COVID-19 on their academic disciplines. Similarities and differences between the disciplines regarding faculty experiences, teaching, and responding to student concerns were discovered. <strong>Results:</strong> Collective review resulted in the identification of four inclusive thematic categories and several sub-categories. These were: academic considerations (didactic, lab, clinical), perceptions (faculty, student), ethical considerations, and social determinants affecting the learning environment. Lessons Learned: This project utilized an innovative interdisciplinary approach to identify common COVID-19 effects on higher education. <strong>Conclusions:</strong> Nursing and other health-related disciplines should pursue interdisciplinary collaboration to address common academic issues that arise during the COVID.展开更多
In this paper,we investigate geothermal exploration and production in 189 hydrothermal projects and 42 hot dry rock projects around the world.The hydrothermal fields for a working hydrothermal system to generate elect...In this paper,we investigate geothermal exploration and production in 189 hydrothermal projects and 42 hot dry rock projects around the world.The hydrothermal fields for a working hydrothermal system to generate electricity should have the elements of heat source,water-saturated porous or fractured reservoir,caprock,heat transfer pathway,and good heat preservation condition and geothermal power energy intensity of 10-20 MW per km^(2)within at least 5 km^(2)area in tectonically active region.The hot water or steam flow rate in this hydrothermal system is normally larger than 40 L/s with temperature of 150℃or above.The power generated from enhanced geothermal system(EGS)in hot dry rock projects are generally less than 2 MW because the flow rate in most cases is much less than 40 L/s even with the hydraulic fractures using the modern stimulation technology learned from the oil and gas industry.The natural fracture in the subsurface is generally beneficial to the hydraulic fracturing and heat recovery in the hot dry rock.Moreover,the hydraulic fracture parameters,injection rate and well spacing,drilling strategy should be properly designed to avoid the short-circuit between injector and producer and low heat productivity.In the future,CO^(2)enhanced geothermal recovery associated with CO^(2)sequestration in the high temperature oil,gas,and geothermal fields maybe a good choice.On the other hand,both nearreal-time seismic monitoring to limit the pumping rate and the closed-loop of the Eavor-Loop style system without hydraulic fracture can contribute greatly to heat recovery of hot dry rocks and mitigate the risks of the hydraulic fracturing induced earthquake.Furthermore,the hybrid solar and geothermal system performs better than the stand-alone geothermal system.展开更多
Innovation in forestry education is needed to address changing contexts of the positionality of forests.This is particularly signifi cant in the Asia–Pacifi c region,where deforestation and degradation are high.Howev...Innovation in forestry education is needed to address changing contexts of the positionality of forests.This is particularly signifi cant in the Asia–Pacifi c region,where deforestation and degradation are high.However,the accessibility of high-quality forestry education to address changing regional and global contexts is lacking.A series of innovative sustainable forest management(SFM)open education resource(OER)courses were developed and implemented to improve the accessibility of SFM education to enhance teaching quality,curriculum,and research capacity of universities in the Asia-Pacifi c Region.To evaluate the SFM-OER program in terms of student experiences,this study investigated student achievement,perceived success of the pedagogical approach and instructional design,and perceived eff ectiveness of the learning activities in promoting active and transformative learning through the assessment of a 1,191-course feedback survey between 2018 and 2020,including the global pandemic.This study revealed that the program attracted diverse student demographics,including a higher proportion of female students majoring in forestry,ecology,and other environmental studies.Their primary motivation to participate in the courses was to gain international experience,followed by the fl exibility of online learning,mandatory course requirements,and earning course credits.Students were satisfi ed with the Canvas learning management system.Most students spent less than 5 to 10 h of their weekly time in the course and agreed or strongly agreed that the workloads were manageable.Students refl ected positively on various learning activities and assignments,such as watching lecture videos,taking quizzes,reading and summarizing,having discussions,and peer review writing.However,they did not clearly prefer specifi c learning activities,signifying the importance of using diverse learning activities to satisfy diverse individual learning styles in online settings.This analysis contributes to the further development of student-centered pedagogical development for online learning and provides insight into the ways forward for online higher forestry education,while repurposing existing OER courses in a post-Covid-19 era.展开更多
Our phenotype includes not only physical features,but also behavioral outputs such as motor schemes and learned skills,and is the result of a complex interaction between genetic background and environment.In fact,a go...Our phenotype includes not only physical features,but also behavioral outputs such as motor schemes and learned skills,and is the result of a complex interaction between genetic background and environment.In fact,a good fraction of last decades’biomedical efforts were dedicated to understanding how different elements(e.g.,genetic polymorphisms,lifestyle components)participate in this interplay,ultimately contributing to affect a given phenotype up to the point of steering it towards pathology.Genetic and epigenetic elements are relatively easy to analyze individually using a reductionist approach,for instance via loss-or gain-of-function studies in cellular and animal models;the effects of nutrients,drugs,pollutants can be similarly tested as single specific stimuli.展开更多
In ST-segment elevation myocardial infarction (STEMI), acute reperfusion of the infarct-related artery (IRA)is the main goal in the early minutes after the patient seeks medical attention. Fibrinolytic therapy (FT) an...In ST-segment elevation myocardial infarction (STEMI), acute reperfusion of the infarct-related artery (IRA)is the main goal in the early minutes after the patient seeks medical attention. Fibrinolytic therapy (FT) and/or primary coronary intervention (PCI) were proven to be effective in opening the IRA.展开更多
文摘1 A study shows that music lessons obviously enhance children's cognitive abilities,including short⁃term memory and planning,which lead to improving academic performance.The research is the first large⁃scale and long⁃term study to be adapted into the regular school curriculum.Visual arts lessons were also found to significantly improve children's visual memory.
基金supported by the National Institute of Natural Hazards,Ministry of Emergency Management of China(2023-JBKY-57)the National Natural Science Foundation of China(42077259)。
文摘Rainfall-induced landslides are often highly destructive.Reviewing and analyzing the causes,processes,impacts,and deficiencies in emergency response is critical for improving disaster prevention and management.From the night of July 21 to the morning of July 22,2024,the Kencho Shacha Gozdi Village in Gezei Gofa,Southern Nations,Nationalities,and Peoples'Region,Ethiopia,suffered heavy rainfall that triggered two landslides.By July25,this event had claimed at least 257 lives.This study presents a detailed characterization of the landslides using multi-source data.By analyzing the landslide disaster process,this study summarizes key lessons and provides suggestions for preventing rainfall-induced geological hazards.The results indicate that rainfall has the greatest impact on the occurrence of landslides,while lithology and human activities have promoted and strengthened the landslide disaster.Despite the active disaster response in the local area,many problems were still exposed in the emergency response work.This analysis offers valuable insights for mitigating rainfall-induced geological hazards and enhancing emergency response capabilities.
文摘African ambassadors reflect on Nujiang’s poverty reduction strategies.Diplomats,government officials,and experts from 34 countries and regions shared experiences in poverty reduction during the 2025 International Forum on Poverty Governance and Global Development held on 29 March in Lushui City,Nujiang Lisu Autonomous Prefecture,Yunnan Province.
文摘Annyeong-haseyo!What pops into your mind when you hear this familiar Korean greeting?K-Dramas?K-Pop idols?The dazzling lights of Seoul?Or advanced microsurgery?What if I told you I experienced all things Korean—strolling the streets in a hanbok,savoring kimchi,and sipping soju—not in South Korea,but in China?
基金Scientific Research Fund of Institute of Engineering Mechanics,China Earthquake Administration under Grant No.2024A03。
文摘On March 28,2025,a catastrophic M 7.9 earthquake shook central Myanmar,causing extensive damage to buildings,significant casualties,and substantial economic loss,making it one of the most severe natural disasters Myanmar has faced in recent years.During an on-site investigation that lasted two weeks,widely spreading liquefaction phenomena and associated damage to buildings and other facilities were investigated in 16 villages or districts in the seismic zones,involving hundreds of residential houses,two large bridges,underground storage tanks,etc.Ground fissures generated by liquefaction tore apart houses,which contributed to a significant impact on house damage.The loss of ground bearing capacity is another impact of liquefaction with regard to structural damage,causing the subsidence and tilting of houses.Several consequences of liquefaction were identified,such as lateral spreading,which demolishes houses and causes casualties,as well as damage to two large bridges as a result of lateral spreading.The cases of liquefaction following the Myanmar earthquake reported on herein provide data and lessons for future seismic desigs to help prevent such disasters in Southeast Asia.Through analyzing the phenomena and characteristics of soil liquefaction,the methods and techniques for liquefaction hazard mitigation in other countries also can be improved.
文摘The provision of water and sanitation services is a key challenge worldwide.The size,complexity,and critical nature of the water and wastewater infrastructure providing such services make the planning and management of these systems extremely difficult.Following the digital revolution in many areas of our lives,the water sector has begun to benefit from digital transformation.Effective utilization of remotely sensed weather and soil moisture data for more efficient irrigation(i.e.,for food production),better detection of anomalies and faults in pipe networks using artificial intelligence,the use of nature-inspired optimization to improve the management and planning of systems,and greater use of digital twins and robotics all exhibit great potential to change and improve the ways in which complex water systems are managed.However,there are additional risks associated with these developments,including—but not limited to—cybersecurity,incorrect use,and overconfidence in the capability and accuracy of digital solutions and automation.This paper identifies key advances in digital technology that have found application in the water sector,and applies forensic engineering principles to failures that have been experienced in industries further ahead with automation and digital transformation.By iden-tifying what went wrong with new digital technologies that might have contributed to high-profile acci-dents in the car and aircraft industries(e.g.,Tesla self-driving cars and the Boeing 737 MAX),it is possible to identify similar risks in the water sector,learn from them,and prevent future failures.The key findings show that:①Automation will require“humans in the loop”;②human operators must be fully aware of the technology and trained to use it;③fallback manual intervention should be available in case of tech-nology malfunctioning;④while redundant sensors may be costly,they reduce the risks due to erroneous sensor readings;⑤cybersecurity risks must be considered;and⑥ethics issues have to be considered,given the increasing automation and interconnectedness of water systems.These findings also point to major research areas related to digital transformation in the water sector.
基金supported by the Intramural Research Programs of the National Eye Institutethe European Union’s Horizon 2020 Research and Innovation programme under the Marie Sklodowska-Curie grant agreement No.749346.
文摘Retinal ganglions cells （RGCs） are responsible for propagating electrochemical information from the eye to the brain along their axons which make up the optic nerve. The loss of RGCs is characteristic in several conditions such as glaucoma and trau- matic optic neuropathy and leads to visual loss and blindness. While no therapy exists to directly treat RGCs, the use of bone marrow-derived mesenchymal stem cells （BMSCs） has shown promise in eliciting significant RGC neuroprotection.
基金"973"National Key Basic Research and Development Program(No.2012CB518202)Project of Qinghai Development of Science and Technology(No.2011-N-150)
文摘On April 14,2010,an earthquake reaching Richter scale 7.1 struck Jiegu Town of Yushu,a mountain rescue operation promptly launched. All injurers had a direct assess to take medical care,and were immediately rescued and rapidly evacuated by air to Xining and Golmud at lower altitudes and admitted to advanced hospitals. Almost all of the injurers have been completely recovered. Yushu Earthquake was one of the highest earthquakes in the world,with a high incidence of acute altitude illness,which was observed in about 80 % of the lowland rescuers at an altitude of 4 000 m."Rescue the rescuers"became the major task of Qinghai-Tibetan rescue teams,all the severe patients were rapidly descended to Xining and treated promptly and effectively. The outcome was excellent,all patients survived. After the earthquake,it is a long and arduous task to reconstruct what has been destroyed. Medical teams continue to work in the Yushu Earthquake area because about 30 000 workers and carders are now here for rebuilding the earthquake center. Thus the prevention and treatment of altitude illness are still critical tasks for medical teams. Although all the fights are successful,there are more experiences and lessons we have learned from the medical mountain rescue during the earthquake and the reconstruction,and reports here are to sum up our experiences from the medical mountain rescue operation in Yushu Earthquake and draw the lessons that we should learn. With the increasing of earthquake probability occurring in the Qinghai-Tibetan Plateau,we also should prepare against earthquake disasters and for further rescue training in the high mountains.
文摘Exercise is a potent force of nature with significant potential for extending longevity and boosting physical fitness. It is also be- ing increasingly used as a prophylactic and curative measure for various physical ailments, such as cardiovascular diseases and diabetes.
基金Binational Science Foundation(BSF)grant number 2015077German Israeli Science Foundation(GIF)grant I-63-410.20-2017,Israeli Science Foundation(ISF)grant 1085/18,and Core Fund Form Tel-Aviv University.
文摘The intestinal microbiome has emerged as an important component involved in various diseases.Therefore,the interest in understanding the factors shaping its composition is growing.The gut microbiome,often defined as a complex trait,contains diverse components and its properties are determined by a combination of external and internal effects.Although much effort has been invested so far,it is still difficult to evaluate the extent to which human genetics shape the composition of the gut microbiota.However,in mouse studies,where the environmental factors are better controlled,the effect of the genetic background was significant.The purpose of this paper is to provide a current assessment of the role of human host genetics in shaping the gut microbiome composition.Despite the inconsistency of the reported results,it can be estimated that the genetic factor affects a portion of the microbiome.However,this effect is currently lower than the initial estimates,and it is difficult to separate the genetic influence from the environmental effect.Additionally,despite the differences between the microbial composition of humans and mice,results from mouse models can strengthen our knowledge of host genetics underlying the human gut microbial variation.
文摘English teaching is an integral part of education,which shoulders the responsibility of rendering rudimentary knowledge of English to the students,providing the students with the listening,speaking,reading and writing ability,as well as the obligation of carrying out ideological education and cultivating their noble and healthy sentiment.In teaching,the teachers should pay special attention to the students' thirst for English learning and give full play to their initiative,which demands enough lead-in preparation before class.The lead-in of new lessons bears a direct impact on the quality of the classroom teaching.This thesis will make an analysis of this problem in two aspects.
基金National Natural Science Foundation of China Under Grant No.90510017Public Welfare Project in Water Conservancy Under Grant No. 200701004
文摘This paper describes some special features of the Wenchuan earthquake that affected dam safety. Damage and performance of dams, primarily for four dams over 100 m high located in the affected earthquake area, are briefly described. Lessons learned related to dam safety from this devastating earthquake are preliminarily drawn. As the seismic safety of high dams during strong earthquakes has gained more attention around the world, some critical issues related to dam construction in China are considered and extensively discussed. Questions such as ＂Why is dam construction necessary in earthquake prone countries such as China？＂, ＂Can we accurately evaluate the seismic safety of high dams in China？＂, ＂Did reservoir impounding of the Zipingpu and Three Gorges Projects trigger the Wenchuan Earthquake in some way？＂ and ＂What is the strategic priority of dam safety for large dams in China？＂ are discussed. Finally, the corresponding tactics with response to the challenge are suggested and recent preliminary progress mainly achieved in IWHR is briefly introduced.
基金supported by grants from the Spanish Ministry of Economy and Competitivenessthe European Regional Development Fund 2007-2013(BFU2014-56300-P)+4 种基金the Xunta de Galicia(GPC2014/030)supported by a grant from the Xunta de Galicia(2016-PG008)a grant from the crowdfunding platform Precipita(FECYTSpanish Ministry of Economy and Competitivenessgrant number 2017-CP081)
文摘Traumatic brain injury （TBI） is a mechanical injury to brain tissue that leads to an impairment of function and a broad spectrum of symptoms and disabilities; often, it is followed by diffuse axonal injury, which causes denaturation of the white matter and axon retraction, leaving patients with severe brain damage or even in a persistent vegetative state.
文摘The agri and food industry is a major industrial sector in Denmark. Compared to other countries on a similar level of economic development Denmark has an extremely important agriculture and agribusiness sector. Danish agri and food cooperatives seem to have been successful in obtaining international competitiveness. The transformation and the structural development of the cooperative sector have more or less been completed. The development of the industrial structure among Danish agricultural cooperatives has been very rapid during the latest decades. Through mergers and acquisitions the number of firms has fallen dramatically, and the result has been increasing concentration ratios in almost all groups of the food industry. Structural development, concentration and globalization in recent decades have resulted in agri and food companies now being among the largest in Europe. To a large extent, agriculture all over the world faces similar problems and challenges. For this reason, it is essential that know-how, experiences and lessons can be transferred and adopted by agriculture in other countries around the world. In many ways, the experience and the success behind Danish agriculture and agribusiness can be transferred to other countries. However, profound studies of specific needs and conditions are necessary.
文摘<strong>Background:</strong> Coronavirus-19 (COVID-19) dramatically impacted institutions of higher education. The effect was acute in the practice disciplines such as medicine, medical laboratory science, and nursing. The purpose is to describe how an interdisciplinary team, led by nursing faculty, adapted to the changes driven by COVID-19 and the lessons that were learned for nursing and other disciplines in higher education. <strong>Method:</strong> The interdisciplinary group created a comprehensive list which captured the impact of COVID-19 on their academic disciplines. Similarities and differences between the disciplines regarding faculty experiences, teaching, and responding to student concerns were discovered. <strong>Results:</strong> Collective review resulted in the identification of four inclusive thematic categories and several sub-categories. These were: academic considerations (didactic, lab, clinical), perceptions (faculty, student), ethical considerations, and social determinants affecting the learning environment. Lessons Learned: This project utilized an innovative interdisciplinary approach to identify common COVID-19 effects on higher education. <strong>Conclusions:</strong> Nursing and other health-related disciplines should pursue interdisciplinary collaboration to address common academic issues that arise during the COVID.
基金This research is funded by the Deep-time Digital Earth(DDE)Big Science Program(DDE Program).
文摘In this paper,we investigate geothermal exploration and production in 189 hydrothermal projects and 42 hot dry rock projects around the world.The hydrothermal fields for a working hydrothermal system to generate electricity should have the elements of heat source,water-saturated porous or fractured reservoir,caprock,heat transfer pathway,and good heat preservation condition and geothermal power energy intensity of 10-20 MW per km^(2)within at least 5 km^(2)area in tectonically active region.The hot water or steam flow rate in this hydrothermal system is normally larger than 40 L/s with temperature of 150℃or above.The power generated from enhanced geothermal system(EGS)in hot dry rock projects are generally less than 2 MW because the flow rate in most cases is much less than 40 L/s even with the hydraulic fractures using the modern stimulation technology learned from the oil and gas industry.The natural fracture in the subsurface is generally beneficial to the hydraulic fracturing and heat recovery in the hot dry rock.Moreover,the hydraulic fracture parameters,injection rate and well spacing,drilling strategy should be properly designed to avoid the short-circuit between injector and producer and low heat productivity.In the future,CO^(2)enhanced geothermal recovery associated with CO^(2)sequestration in the high temperature oil,gas,and geothermal fields maybe a good choice.On the other hand,both nearreal-time seismic monitoring to limit the pumping rate and the closed-loop of the Eavor-Loop style system without hydraulic fracture can contribute greatly to heat recovery of hot dry rocks and mitigate the risks of the hydraulic fracturing induced earthquake.Furthermore,the hybrid solar and geothermal system performs better than the stand-alone geothermal system.
基金Asia-Pacifi c Network for Sustainable Forest Management and Rehabilitation SFM-ORE-2018。
文摘Innovation in forestry education is needed to address changing contexts of the positionality of forests.This is particularly signifi cant in the Asia–Pacifi c region,where deforestation and degradation are high.However,the accessibility of high-quality forestry education to address changing regional and global contexts is lacking.A series of innovative sustainable forest management(SFM)open education resource(OER)courses were developed and implemented to improve the accessibility of SFM education to enhance teaching quality,curriculum,and research capacity of universities in the Asia-Pacifi c Region.To evaluate the SFM-OER program in terms of student experiences,this study investigated student achievement,perceived success of the pedagogical approach and instructional design,and perceived eff ectiveness of the learning activities in promoting active and transformative learning through the assessment of a 1,191-course feedback survey between 2018 and 2020,including the global pandemic.This study revealed that the program attracted diverse student demographics,including a higher proportion of female students majoring in forestry,ecology,and other environmental studies.Their primary motivation to participate in the courses was to gain international experience,followed by the fl exibility of online learning,mandatory course requirements,and earning course credits.Students were satisfi ed with the Canvas learning management system.Most students spent less than 5 to 10 h of their weekly time in the course and agreed or strongly agreed that the workloads were manageable.Students refl ected positively on various learning activities and assignments,such as watching lecture videos,taking quizzes,reading and summarizing,having discussions,and peer review writing.However,they did not clearly prefer specifi c learning activities,signifying the importance of using diverse learning activities to satisfy diverse individual learning styles in online settings.This analysis contributes to the further development of student-centered pedagogical development for online learning and provides insight into the ways forward for online higher forestry education,while repurposing existing OER courses in a post-Covid-19 era.
文摘Our phenotype includes not only physical features,but also behavioral outputs such as motor schemes and learned skills,and is the result of a complex interaction between genetic background and environment.In fact,a good fraction of last decades’biomedical efforts were dedicated to understanding how different elements(e.g.,genetic polymorphisms,lifestyle components)participate in this interplay,ultimately contributing to affect a given phenotype up to the point of steering it towards pathology.Genetic and epigenetic elements are relatively easy to analyze individually using a reductionist approach,for instance via loss-or gain-of-function studies in cellular and animal models;the effects of nutrients,drugs,pollutants can be similarly tested as single specific stimuli.
文摘In ST-segment elevation myocardial infarction (STEMI), acute reperfusion of the infarct-related artery (IRA)is the main goal in the early minutes after the patient seeks medical attention. Fibrinolytic therapy (FT) and/or primary coronary intervention (PCI) were proven to be effective in opening the IRA.
