AIM:To investigate the ocular biological characteristics of children with myopia and rapid axial length(AL)changes prescribed spectacles with highly aspherical lenslets(HAL).METHODS:Data were collected from 156 childr...AIM:To investigate the ocular biological characteristics of children with myopia and rapid axial length(AL)changes prescribed spectacles with highly aspherical lenslets(HAL).METHODS:Data were collected from 156 children(252 eyes)with myopia and HAL treatment who were aged 7-13 and had rapid AL changes.The participants were divided into groups with AL reduction and elongation according to the changes in AL within 6mo.Paired t-tests were used to compare the ocular biological parameters at baseline and after rapid changes post-HAL treatment.Pearson’s correlation analysis was used to determine the association between the ocular parameters and AL changes.RESULTS:The ocular biological parameters significantly changed in the children with myopia and rapid AL changes after HAL treatment.In the group with AL reduction,the anterior chamber depth(ACD)and vitreous chamber depth(VCD)decreased.The crystalline lens thickness(CLT)increased,corneal flat keratometry(FK)decreased,and steep keratometry(SK)increased(all P<0.001).The eyes in the group with AL elongation had increased ACD and VCD and steepened SK,but the CLT or FK findings were not different.AL change was negatively associated with baseline astigmatism(r=-0.171;P=0.007).CONCLUSION:In the eyes with HAL treatment,decreased ACD and VCD,thickened CLT,flattened FK,and steepened SK are observed during AL reduction.Lower baseline astigmatism is associated with AL reduction.The AL reduction may suggest the potential efficacy of HAL intervention in myopia control,while providing evidence for optimizing personalized myopia management strategies.Further longitudinal studies are warranted to validate whether rapid AL changes predict sustained treatment efficacy.展开更多
Objectives:To investigate the short-and long-term effects of myopia control spectacle lenses with highly aspherical lenslets(HAL)and slightly aspherical lenslets(SAL)on visual function and visual quality using data ob...Objectives:To investigate the short-and long-term effects of myopia control spectacle lenses with highly aspherical lenslets(HAL)and slightly aspherical lenslets(SAL)on visual function and visual quality using data obtained from a randomized controlled clinical trial.Methods:This was a prospective,randomized,controlled,and double-blinded study;170 myopic children aged 8–13 years were randomly assigned to the HAL,SAL,or single-vision spectacle lenses(SVL)groups.Distance and near visual acuity(VA)at high(100%)and low(10%)contrast in photopic and scotopic conditions,near phoria,stereoacuity,and accommodative lag,microfluctuations(AMFs),amplitude(AA)were measured after wearing lenses for 10 min,6 months,and 12 months.Results:In total,161 subjects completed all follow-up in 12 months and were included in the analysis.After 10 min of wearing,the HAL and SAL groups had lower scotopic and low-contrast VA than the SVL group(decreased 0.03–0.08 logMAR and 0.01–0.04 logMAR in different VAs in the HAL and SAL groups,respectively,all P<0.05).The reduction in VA was recovered at 12 months as the HAL and SAL groups exhibited significant VA improvements,and the VA was not different among the three groups(all P>0.05).The HAL and SAL groups had significantly larger AMFs than the SVL group(HAL vs.SAL vs.SVL:0.21±0.08 D vs.0.16±0.05 D vs.0.15±0.06 D at baseline,0.19±0.07 D vs.0.17±0.05 D vs.0.13±0.07 D at 12 months,all P<0.05).There were no significant differences in accommodative lag,AA,or phoria between the groups(all P>0.05).The HAL and SAL groups had reduced stereoacuity compared to the SVL group at baseline(70’vs.60’vs.50’,P=0.005),but no difference was observed at 12 months(70’vs.70’vs.70’,P=0.11).Conclusions:HAL and SAL have no significant influence on accommodation and phoria except had larger AMF than SVL.Scotopic VA and low-contrast VA are reduced with short-term HAL and SAL use but recovered to be at same level with the SVL after 1 year of use.展开更多
In order to improve depth extraction accuracy, a method using moving array lenslet technique(MALT) in pickup stage is proposed, which can decrease the depth interval caused by pixelation. In this method, the lenslet a...In order to improve depth extraction accuracy, a method using moving array lenslet technique(MALT) in pickup stage is proposed, which can decrease the depth interval caused by pixelation. In this method, the lenslet array is moved along the horizontal and vertical directions simultaneously for N times in a pitch to get N sets of elemental images. Computational integral imaging reconstruction method for MALT is taken to obtain the slice images of the 3 D scene, and the sum modulus(SMD) blur metric is taken on these slice images to achieve the depth information of the 3 D scene. Simulation and optical experiments are carried out to verify the feasibility of this method.展开更多
基金Supported by the Medical Science and Technology Project of Zhejiang Province of China(No.2020KY191).
文摘AIM:To investigate the ocular biological characteristics of children with myopia and rapid axial length(AL)changes prescribed spectacles with highly aspherical lenslets(HAL).METHODS:Data were collected from 156 children(252 eyes)with myopia and HAL treatment who were aged 7-13 and had rapid AL changes.The participants were divided into groups with AL reduction and elongation according to the changes in AL within 6mo.Paired t-tests were used to compare the ocular biological parameters at baseline and after rapid changes post-HAL treatment.Pearson’s correlation analysis was used to determine the association between the ocular parameters and AL changes.RESULTS:The ocular biological parameters significantly changed in the children with myopia and rapid AL changes after HAL treatment.In the group with AL reduction,the anterior chamber depth(ACD)and vitreous chamber depth(VCD)decreased.The crystalline lens thickness(CLT)increased,corneal flat keratometry(FK)decreased,and steep keratometry(SK)increased(all P<0.001).The eyes in the group with AL elongation had increased ACD and VCD and steepened SK,but the CLT or FK findings were not different.AL change was negatively associated with baseline astigmatism(r=-0.171;P=0.007).CONCLUSION:In the eyes with HAL treatment,decreased ACD and VCD,thickened CLT,flattened FK,and steepened SK are observed during AL reduction.Lower baseline astigmatism is associated with AL reduction.The AL reduction may suggest the potential efficacy of HAL intervention in myopia control,while providing evidence for optimizing personalized myopia management strategies.Further longitudinal studies are warranted to validate whether rapid AL changes predict sustained treatment efficacy.
基金supported by the International S&T Cooperation Program of China(Grant No.2014DFA30940)Collaborative research project with Essilor International(Wenzhou Medical University Grant Nos.95013006,95016010 and 95020005).
文摘Objectives:To investigate the short-and long-term effects of myopia control spectacle lenses with highly aspherical lenslets(HAL)and slightly aspherical lenslets(SAL)on visual function and visual quality using data obtained from a randomized controlled clinical trial.Methods:This was a prospective,randomized,controlled,and double-blinded study;170 myopic children aged 8–13 years were randomly assigned to the HAL,SAL,or single-vision spectacle lenses(SVL)groups.Distance and near visual acuity(VA)at high(100%)and low(10%)contrast in photopic and scotopic conditions,near phoria,stereoacuity,and accommodative lag,microfluctuations(AMFs),amplitude(AA)were measured after wearing lenses for 10 min,6 months,and 12 months.Results:In total,161 subjects completed all follow-up in 12 months and were included in the analysis.After 10 min of wearing,the HAL and SAL groups had lower scotopic and low-contrast VA than the SVL group(decreased 0.03–0.08 logMAR and 0.01–0.04 logMAR in different VAs in the HAL and SAL groups,respectively,all P<0.05).The reduction in VA was recovered at 12 months as the HAL and SAL groups exhibited significant VA improvements,and the VA was not different among the three groups(all P>0.05).The HAL and SAL groups had significantly larger AMFs than the SVL group(HAL vs.SAL vs.SVL:0.21±0.08 D vs.0.16±0.05 D vs.0.15±0.06 D at baseline,0.19±0.07 D vs.0.17±0.05 D vs.0.13±0.07 D at 12 months,all P<0.05).There were no significant differences in accommodative lag,AA,or phoria between the groups(all P>0.05).The HAL and SAL groups had reduced stereoacuity compared to the SVL group at baseline(70’vs.60’vs.50’,P=0.005),but no difference was observed at 12 months(70’vs.70’vs.70’,P=0.11).Conclusions:HAL and SAL have no significant influence on accommodation and phoria except had larger AMF than SVL.Scotopic VA and low-contrast VA are reduced with short-term HAL and SAL use but recovered to be at same level with the SVL after 1 year of use.
基金supported by the National Natural Science Foundation of China(Nos.11474169 and 61675100)the Tianjin Natural Science Foundation(No.15JCYBJC16900)
文摘In order to improve depth extraction accuracy, a method using moving array lenslet technique(MALT) in pickup stage is proposed, which can decrease the depth interval caused by pixelation. In this method, the lenslet array is moved along the horizontal and vertical directions simultaneously for N times in a pitch to get N sets of elemental images. Computational integral imaging reconstruction method for MALT is taken to obtain the slice images of the 3 D scene, and the sum modulus(SMD) blur metric is taken on these slice images to achieve the depth information of the 3 D scene. Simulation and optical experiments are carried out to verify the feasibility of this method.
