Objective To identify risk factors contributing to prolonged postoperative length of stay(LOS)in very elderly patients following hip fracture surgery,with a focus on postoperative complications and the impact of diffe...Objective To identify risk factors contributing to prolonged postoperative length of stay(LOS)in very elderly patients following hip fracture surgery,with a focus on postoperative complications and the impact of different anesthesia approaches.Methods This retrospective single-center cohort study enrolled patients aged 90 years or older who underwent hip fracture surgery at Peking Union Medical College Hospital between January 31,2013 and December 31,2023.Relevant perioperative data were collected.The primary outcome was postoperative LOS,and the study cohort was divided into two groups:postoperative LOS≤7 days and LOS>7 days.Logistic regression was performed to identify factors related to prolonged postoperative LOS.Results A total of 155 patients were included.The average age was 92.7±2.6 years.There were 73(47%)patients with postoperative LOS>7 days.Postoperative pneumonia was the only factor associated with a prolonged postoperative LOS(OR=2.12,95%CI[1.09,4.16],P=0.028).Neither the type of anesthesia(regional vs.general anesthesia,OR=1.00,95%CI[0.53,1.90],P=0.993)nor the method of airway management(laryngeal mask ventilation vs.spontaneous breathing,OR=1.46,95%CI[0.58,3.76],P=0.424;endotracheal intubation vs.spontaneous breathing,OR=0.82,95%CI[0.39,1.69],P=0.592)showed a significant association with a prolonged postoperative LOS.Preoperative chronic obstructive pulmonary disease(OR=2.78,95%CI[1.05,7.65],P=0.040)and preoperative neutrophil count(OR=1.13,95%CI[1.01,1.26],P=0.029)were both significantly associated with the occurrence of postoperative pneumonia,while anesthesia type and airway management method were not.Conclusions Postoperative pneumonia was associated with prolonged postoperative LOS in very elderly patients undergoing hip fracture surgery,whereas anesthesia types and airway management methods show no association with prolonged postoperative LOS or postoperative pneumonia.Preoperative comorbidities,especially respiratory conditions and systemic inflammation,potentially play a substantial role in postoperative recovery.展开更多
BACKGROUND Red blood cell distribution width(RDW)is associated with the development and progression of various diseases.AIM To explore the association between pretreatment RDW and short-term outcomes after laparoscopi...BACKGROUND Red blood cell distribution width(RDW)is associated with the development and progression of various diseases.AIM To explore the association between pretreatment RDW and short-term outcomes after laparoscopic pancreatoduodenectomy(LPD).METHODS A total of 804 consecutive patients who underwent LPD at our hospital between March 2017 and November 2021 were retrospectively analyzed.Correlations between pretreatment RDW and clinicopathological characteristics and short-term outcomes were investigated.RESULTS Patients with higher pretreatment RDW were older,had higher Eastern Cooperative Oncology Group scores and were associated with poorer short-term outcomes than those with normal RDW.High pretreatment RDW was an independent risk factor for postoperative complications(POCs)(hazard ratio=2.973,95%confidence interval:2.032-4.350,P<0.001)and severe POCs of grade IIIa or higher(hazard ratio=3.138,95%confidence interval:2.042-4.824,P<0.001)based on the Clavien-Dino classification system.Subgroup analysis showed that high pretreatment RDW was an independent risk factor for Clavien-Dino classi-fication grade IIIb or higher POCs,a comprehensive complication index score≥26.2,severe postoperative pancreatic fistula,severe bile leakage and severe hemorrhage.High pretreatment RDW was positively associated with the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio and was negatively associated with albumin and the prognostic nutritional index.CONCLUSION Pretreatment RDW was a special parameter for patients who underwent LPD.It was associated with malnutrition,severe inflammatory status and poorer short-term outcomes.RDW could be a surrogate marker for nutritional and inflammatory status in identifying patients who were at high risk of developing POCs after LPD.展开更多
To cater the need for real-time crack monitoring of infrastructural facilities,a CNN-regression model is proposed to directly estimate the crack properties from patches.RGB crack images and their corresponding masks o...To cater the need for real-time crack monitoring of infrastructural facilities,a CNN-regression model is proposed to directly estimate the crack properties from patches.RGB crack images and their corresponding masks obtained from a public dataset are cropped into patches of 256 square pixels that are classified with a pre-trained deep convolution neural network,the true positives are segmented,and crack properties are extracted using two different methods.The first method is primarily based on active contour models and level-set segmentation and the second method consists of the domain adaptation of a mathematical morphology-based method known as FIL-FINDER.A statistical test has been performed for the comparison of the stated methods and a database prepared with the more suitable method.An advanced convolution neural network-based multi-output regression model has been proposed which was trained with the prepared database and validated with the held-out dataset for the prediction of crack-length,crack-width,and width-uncertainty directly from input image patches.The pro-posed model has been tested on crack patches collected from different locations.Huber loss has been used to ensure the robustness of the proposed model selected from a set of 288 different variations of it.Additionally,an ablation study has been conducted on the top 3 models that demonstrated the influence of each network component on the pre-diction results.Finally,the best performing model HHc-X among the top 3 has been proposed that predicted crack properties which are in close agreement to the ground truths in the test data.展开更多
The minimal widths of three bounded subsets of the unit sphere associated to a unit vector in a normed linear space are studied,and three related geometric constants are introduced.New characterizations of inner produ...The minimal widths of three bounded subsets of the unit sphere associated to a unit vector in a normed linear space are studied,and three related geometric constants are introduced.New characterizations of inner product spaces are also presented.From the perspective of minimal width,strongε-symmetry of Birkhoff orthogonality is introduced,and its relation toε-symmetry of Birkhoff orthogonality is shown.Unlike most of the existing parameters of the underlying space,these new constants are full dimensional in nature.展开更多
BACKGROUND Leg length discrepancy(LLD)following total hip arthroplasty(THA)is a common complaint,leading to decreased patient satisfaction.However,the effect of LLD before THA on outcomes and complications is not well...BACKGROUND Leg length discrepancy(LLD)following total hip arthroplasty(THA)is a common complaint,leading to decreased patient satisfaction.However,the effect of LLD before THA on outcomes and complications is not well defined.AIM To assess the effect of prior LLD on rates of falls,implant-related complications,stay length,readmissions,and implant survival following THA.METHODS A retrospective review of a nationwide insurance database was conducted from 2010 to 2021.All cases of THA and those with a prior diagnosis of LLD were identified.THA patients with LLD were matched to control patients 1:5 based on demographic and comorbidity profiles.Two-year fall rates and implant complications,lengths of stay,90-day readmissions,and time to revision were compared between cohorts.RESULTS A total of 2038 patients with LLD were matched to 10165 control patients.The LLD group showed significantly greater rates of falls[odds ratio(OR)=1.58;95%confidence interval(95%CI):1.24-2.01],dislocation(OR=2.61;95%CI:2.10-3.24),mechanical loosening(OR=4.58;95%CI:3.28-6.29),and periprosthetic fracture(OR=2.70;95%CI:1.96-3.72)compared to the control group(all P<0.001).Mean length of stay(LOS)was also significantly higher in the LLD group(3.1 days vs 2.8 days,P=0.034).No significant difference in 90-day readmission rates(7.75%vs 7.02%,P=0.244)was observed between the groups(P=0.244).Time to revision was significantly less in the LLD group(225 days vs 544 days,P<0.001).CONCLUSION LLD in patients having THA is related with significantly higher fall risk,rates of implant-related complications,LOS,and quicker time to revision.Identifying patients with LLD before their THA may help in identifying risks,better patient counselling,and more effective preoperative planning.However,the study have important limitations:Its design lacks information on the degree and cause of LLD,the time between diagnosis and surgery,and which leg with the discrepancy underwent the operation.Future well-designed studies should confirm the findings of this study.展开更多
Intracranial aneurysm(IA)is a prevalent cerebrovascular disease associated with high mortality and disability rates upon rupture.The hemodynamics of IA,which are significantly influenced by geometric parameters,direct...Intracranial aneurysm(IA)is a prevalent cerebrovascular disease associated with high mortality and disability rates upon rupture.The hemodynamics of IA,which are significantly influenced by geometric parameters,directly impact its rupture.This study focuses on investigating the transient flow characteristics in saccular IA models fabricated using a water droplet-based method,specifically examining the influence of neck widths.Particle image velocimetry technique and numerical simulation were employed to investigate the dynamic evolution of flow structures within three IA models.The results reveal that neck width(W)has a substantial effect on flow characteristics in the neck region,subsequently impacting the deep flow inside the sac.Three distinct patterns were observed during flow evolution inside the sac:for W=2 mm,two vortices occur and then disappear with relatively low average flow velocity;for W=4 mm,enhanced effects of a high-speed jet result in periodic pulsatile flow velocity distribution while maintaining stable vortex core position;for W=6 mm,significant changes in flow velocity occur due to size expansion and intensity increase of vortices.These findings demonstrate that neck widths play a complex role in influencing transient flow characteristics within IAs.Overall,this research contributes to further understanding transient flow behaviors in IAs.展开更多
Objective:To explore the correlation between fetal foot length measured by ultrasound and gestational age.Methods:This study employed ultrasound to measure the fetal foot length,femoral length,and foot length/femoral ...Objective:To explore the correlation between fetal foot length measured by ultrasound and gestational age.Methods:This study employed ultrasound to measure the fetal foot length,femoral length,and foot length/femoral length ratio in 214 pregnant women from 12 to 40 weeks of gestation,all of whom had no pregnancy complications or obstetric complications,and whose fetuses were normal.Results:A significant positive correlation was found between fetal foot length and gestational age(r=0.967,p<0.001);a similarly significant positive correlation was observed between fetal femoral length and gestational age(r=0.972,p<0.001);and a non-significant positive correlation was noted between the foot length/femoral length ratio and gestational age(r=0.943,p<0.001).Conclusion:Ultrasound can accurately measure fetal foot length and femoral length,both of which exhibit a significant positive correlation with gestational age,making them important reference indicators for assessing fetal growth and development.展开更多
BACKGROUND Post-hepatectomy liver failure(PHLF)after liver resection is one of the main complications causing postoperative death in patients with hepatocellular carcinoma(HCC).It is crucial to help clinicians identif...BACKGROUND Post-hepatectomy liver failure(PHLF)after liver resection is one of the main complications causing postoperative death in patients with hepatocellular carcinoma(HCC).It is crucial to help clinicians identify potential high-risk PHLF patients as early as possible through preoperative evaluation.AIM To identify risk factors for PHLF and develop a prediction model.METHODS This study included 248 patients with HCC at The Second Affiliated Hospital of Air Force Medical University between January 2014 and December 2023;these patients were divided into a training group(n=164)and a validation group(n=84)via random sampling.The independent variables for the occurrence of PHLF were identified by univariate and multivariate analyses and visualized as nomograms.Ultimately,comparisons were made with traditional models via receiver operating characteristic(ROC)curves,calibration curves,and decision curve analysis(DCA).RESULTS In this study,portal vein width[odds ratio(OR)=1.603,95%CI:1.288-1.994,P≤0.001],the preoperative neutrophil-to-lymphocyte ratio(NLR)(OR=1.495,95%CI:1.126-1.984,P=0.005),and the albumin-bilirubin(ALBI)score(OR=8.868,95%CI:2.144-36.678,P=0.003)were independent risk factors for PHLF.A nomogram prediction model was developed using these factors.ROC and DCA analyses revealed that the predictive efficacy and clinical value of this model were better than those of traditional models.CONCLUSION A new Nomogram model for predicting PHLF in HCC patients was successfully established based on portal vein width,the NLR,and the ALBI score,which outperforms the traditional model.展开更多
BACKGROUND As red blood cell distribution width(RDW)and albumin have been shown to be independent predictors of mortality from various diseases,this study aimed to investigate the effect of the RDW to albumin ratio(RA...BACKGROUND As red blood cell distribution width(RDW)and albumin have been shown to be independent predictors of mortality from various diseases,this study aimed to investigate the effect of the RDW to albumin ratio(RA)as an independent predictor of the prognosis of patients admitted to the coronary care unit(CCU).AIM To use the RDW and albumin level to predict the prognosis of patients in the CCU.METHODS Data were obtained from the Medical Information Mart Intensive Care III database.The primary outcome was 365-day all-cause mortality,whereas the secondary outcomes were 30-and 90-day all-cause mortality,hospital length of stay(LOS),and CCU LOS.Cox proportional hazards regression model,propen-sity score matching,and receiver operating characteristic curve analyses were used.RESULTS The hazard ratio(95%confidence interval)of the upper tertile(RA>4.66)was 1.62(1.29 to 2.03)when compared with the reference(RA<3.84)in 365-day all-cause mortality.This trend persisted after adjusting for demographic and clinical variables in the propensity score-matching analysis.Similar trends were observed for the secondary outcomes of hospital and CCU LOS.Receiver operating characteristic curve analysis was performed by combining the RA and sequential organ failure assessment(SOFA)scores,and the C-statistic was higher than that of the SOFA scores(0.733 vs 0.702,P<0.001).CONCLUSION RA is an independent prognostic factor in patients admitted to the CCU.RA combined with the SOFA score can improve the predictive ability of the SOFA score.However,our results should be verified in future prospective studies.展开更多
Accurate prediction of strip width is a key factor related to the quality of hot rolling manufacture.Firstly,based on strip width formation mechanism model within strip rolling process,an improved width mechanism calc...Accurate prediction of strip width is a key factor related to the quality of hot rolling manufacture.Firstly,based on strip width formation mechanism model within strip rolling process,an improved width mechanism calculation model is delineated for the optimization of process parameters via the particle swarm optimization algorithm.Subsequently,a hybrid strip width prediction model is proposed by effectively combining the respective advantages of the improved mechanism model and the data-driven model.In acknowledgment of prerequisite for positive error in strip width prediction,an adaptive width error compensation algorithm is proposed.Finally,comparative simulation experiments are designed on the actual rolling dataset after completing data cleaning and feature engineering.The experimental results show that the hybrid prediction model proposed has superior precision and robustness compared with the improved mechanism model and the other eight common data-driven models and satisfies the needs of practical applications.Moreover,the hybrid model can realize the complementary advantages of the mechanism model and the data-driven model,effectively alleviating the problems of difficult to improve the accuracy of the mechanism model and poor interpretability of the data-driven model,which bears significant practical implications for the research of strip width control.展开更多
AIM:To investigate the ocular biological characteristics of children with myopia and rapid axial length(AL)changes prescribed spectacles with highly aspherical lenslets(HAL).METHODS:Data were collected from 156 childr...AIM:To investigate the ocular biological characteristics of children with myopia and rapid axial length(AL)changes prescribed spectacles with highly aspherical lenslets(HAL).METHODS:Data were collected from 156 children(252 eyes)with myopia and HAL treatment who were aged 7-13 and had rapid AL changes.The participants were divided into groups with AL reduction and elongation according to the changes in AL within 6mo.Paired t-tests were used to compare the ocular biological parameters at baseline and after rapid changes post-HAL treatment.Pearson’s correlation analysis was used to determine the association between the ocular parameters and AL changes.RESULTS:The ocular biological parameters significantly changed in the children with myopia and rapid AL changes after HAL treatment.In the group with AL reduction,the anterior chamber depth(ACD)and vitreous chamber depth(VCD)decreased.The crystalline lens thickness(CLT)increased,corneal flat keratometry(FK)decreased,and steep keratometry(SK)increased(all P<0.001).The eyes in the group with AL elongation had increased ACD and VCD and steepened SK,but the CLT or FK findings were not different.AL change was negatively associated with baseline astigmatism(r=-0.171;P=0.007).CONCLUSION:In the eyes with HAL treatment,decreased ACD and VCD,thickened CLT,flattened FK,and steepened SK are observed during AL reduction.Lower baseline astigmatism is associated with AL reduction.The AL reduction may suggest the potential efficacy of HAL intervention in myopia control,while providing evidence for optimizing personalized myopia management strategies.Further longitudinal studies are warranted to validate whether rapid AL changes predict sustained treatment efficacy.展开更多
AIM:To evaluate the efficacy of the Tecnis Symfony ZXR00 lens in achieving optimal visual outcomes for cataract surgery patients with axial length(AL)shorter than 24 mm.METHODS:A total of 21 subjects(37 eyes)were subm...AIM:To evaluate the efficacy of the Tecnis Symfony ZXR00 lens in achieving optimal visual outcomes for cataract surgery patients with axial length(AL)shorter than 24 mm.METHODS:A total of 21 subjects(37 eyes)were submitted to cataract surgery and implantation of Tecnis Symfony ZXR00 lens(Johnson&Johnson Vision)was assessed.Patients were examined at 5 m,80 cm,and 40 cm for uncorrected distance visual acuity(UCDVA)and corrected distance visual acuity(CDVA),uncorrected intermediate(UCIVA),and uncorrected near visual acuity(UCNVA).Further,based on the optimal distance correction,the monocular defocusing curve in the range of+0.5 to-3.5 D was investigated.A simple patient-reported spectacle independence questionnaire(PRSIQ)was used to evaluate subjects’subjective feelings about their dependence on glasses at various distances.Multiple linear regression was employed to examine the association amony intraocular lenses(IOLs)diopter,AL,corneal curvature,anterior chamber depth,mean manifest refractive spherical equivalent,pupil,pupil/scan,target refraction,and near vision(logMAR).RESULTS:The study demonstrated enhanced UCNVA alongside comparable distant vision and UCIVA outcomes in eyes with AL shorter than 24 mm.Mean post-operative UCDVA significantly improved from preoperative levels 0.530±0.406(P=0.000).Notably,83.3%of eyes achieved 0.01 logMAR in UCNVA.Five unilateral cases with blended IOL implantation also showed satisfactory visual acuity and satisfaction.The 90.5%(19/21)achieved spectacle independence.The average score for self-reported spectacle-independence on the PRSIQ was 3.52 with a standard deviation of 0.98.The results of the regression analysis revealed that one predictor,the pupil/scan accounted for 27.6%of the variation in near vision[logMAR;F(1,35)=13.33,P<0.01].CONCLUSION:The results affirm the effectiveness of the Tecnis Symfony ZXR00 lens in enhancing visual outcomes for cataract surgery patients with AL shorter than 24 mm.Additionally,the pupil/scan emerges as a critical factor influencing postoperative near vision.展开更多
We report an interesting and abnormal electromagnetic phenomenon with regard to a terajet(TJ)that is generated in a reflection mode,which is realized by placing a dielectric scatterer onto a metal reflection plate.We ...We report an interesting and abnormal electromagnetic phenomenon with regard to a terajet(TJ)that is generated in a reflection mode,which is realized by placing a dielectric scatterer onto a metal reflection plate.We show that the introduction of an air hollow into metal reflection plate beneath the scatterer does not induce an expected decrease but an abnormal increase of focal length of the TJ by as much as more than three times.This abnormal phenomenon takes place in case that the air hollow is shallow and there exists a critical hollow depth for a given lateral size of air hollow.Larger than the critical depth,the phenomenon no longer occurs.It is explained from viewpoints of both ray optics in terms of role of relative portion of central waves in TJ formation and electromagnetic field theory with regard to hollow-induced phase singularities.展开更多
Grain size is a crucial factor influencing both rice yield and appearance quality.In this study,we identified GL6.1 as a gene associated with rice grain size by map-based cloning.The GL6.1 encodes a protein with CC-NB...Grain size is a crucial factor influencing both rice yield and appearance quality.In this study,we identified GL6.1 as a gene associated with rice grain size by map-based cloning.The GL6.1 encodes a protein with CC-NB-LRR domain,a structural motif related to rice disease resistance.Genetic transformation experiments and the construction of gene pyramiding lines indicate that GL6.1 functions as a negative regulatory factor for rice grain length.By the analysis of SSSLs with diverse donor parents,a total of 11 single nucleotide polymorphisms(SNPs)are identified that are closely associated with the phenotype variations.A yeast one-hybrid library screening revealed that GL6.1 interacts with OsWRKY53,a transcription factor associated with rice disease resistance.Furthermore,RNA-seq assay also revealed the involvement of pathways associated with disease resistance,hinting at a multifaceted role for GL6.1 in both yield and stress tolerance traits in rice.These results indicate that the cloning and in-depth studies of GL6.1 would provide valuable insights into the interplay among high yield,superior quality,and stress tolerance,which are critical goals for rice breeding.展开更多
A self-pulsed Tm:GdScO_(3)laser was experimentally demonstrated by using a compact linear resonant cavity.When the pump power was 19.6 W,an average output power of 1771 m W was achieved from the self-pulsed Tm:GdScO_(...A self-pulsed Tm:GdScO_(3)laser was experimentally demonstrated by using a compact linear resonant cavity.When the pump power was 19.6 W,an average output power of 1771 m W was achieved from the self-pulsed Tm:GdScO_(3)laser with a pulse width of 158.1 ns and a pulse repetition frequency of 112.8 kHz,corresponding to an optical-to-optical conversion efficiency of 9.0%.Moreover,a single pulse energy of 15.7μJ and a pulse peak power of 99.3 W were acquired from the self-pulsed Tm:GdScO_(3)laser.This is,as we know,the first time that the self-pulsed laser output at 2-μm waveband range was obtained by utilizing a Tm:GdScO_(3)crystal so far.展开更多
AIM:To compare the effects of different types of negative pressure suction on the macular and optic disc retinal vessel density(VD)in myopic patients with different axial lengths(ALs)undergoing femtosecond laser-assis...AIM:To compare the effects of different types of negative pressure suction on the macular and optic disc retinal vessel density(VD)in myopic patients with different axial lengths(ALs)undergoing femtosecond laser-assisted excimer laser in situ keratomileusis(FS-LASIK)by optical coherence tomography angiography(OCTA).METHODS:A prospective,nonrandomized,controlled study.Participants underwent FS-LASIK surgery were divided into the short AL group(SAL,22≤AL<26 mm)and the long AL group(LAL,26≤AL<28 mm)according to the different ALs.Further,the two groups were divided into subgroups according to the corneal flap using VisuMax or WaveLight FS200 femtosecond laser(FS)platform.All patients underwent OCTA before the surgery and 1-day/1-week/1-month after the surgery.ANOVA statistically analyzed data with two-factor repeated measurement in SPSS.RESULTS:Totally 108 participants(108 eyes,18–35y)were divided into SAL group[22 patients(4 males and 18 females)were treated with VisuMax,and 24(3 males and 21 females)were treated with WaveLight FS200]and LAL group[34 patients(4 males and 30 females)were treated with VisuMax,and 28 patients(6 males and 22 females)were treated with WaveLight FS200].In the LAL group,there was no significant difference in macular superficial capillary plexuses vessel density(SCP-VD)in the fovea and perifovea region,but compared with the VisuMax subgroup,SCP-VD in the parafoveal region(t=2.647,P=0.010)and the whole area(t=2.030,P=0.047)in WaveLight FS200 subgroup decreased at one day after the operation and increased to a preoperative level at 1-week and 1-month after operation.There was no significant difference between SCP-VD in the two SAL subgroups,neither of deep capillary plexuses vessel density(DCP-VD)and optic nerve head vessel density(ONH-VD)in the SAL and LAL groups.CONCLUSION:With the increase of AL and suction intensity,a transient decrease of SCP-VD in the macular region is observed at 1d postoperatively during FS-LASIK,and it increases to preoperative level at 1-week and 1-month postoperatively.However,the AL and suction intensity do not affect the macular DCP-VD and ONH-VD.展开更多
The crystallization behavior of polymers is significantly influenced by molecular chain length and the dispersion of varying chain lengths.The complexity of studying crystallization arises from the dispersity of polym...The crystallization behavior of polymers is significantly influenced by molecular chain length and the dispersion of varying chain lengths.The complexity of studying crystallization arises from the dispersity of polymer materials and the typically slow cooling rates.Recent advancements in fast cooling techniques have rendered the investigation of polymer crystallization at varying cooling rates an attractive area of research;however,a systematic quantitative framework for this process is still lacking.We employ a coarse-grained model for polyvinyl alcohol(CGPVA)in molecular dynamics simulations to study the crystallization of linear polymers with varying chain lengths under variable cooling rates.Monodisperse,bidisperse and polydisperse samples are simulated.We propose two formulae based on a two-phase assumption to fit the exothermal curves obtained during cooling.Based on these formulae,better estimations of crystallization temperatures are obtained and the effects of chain lengths and cooling rates are studied.It is found that the crystallization temperature increases with chain length,similar to the Gibbs-Thomson relation formelting temperature,indicating a strong relation between fast crystallization and glass formation in linear polymers.Extrapolation to the infinitely slow cooling rate provides an easy way in simulations to estimate the equilibrium crystallization temperature.The effective chain lengths of polydisperse and bidisperse samples are found to be the number-averaged chain lengths compared to the weight-averaged ones.The chain length-dependent crystallization exhibits crossover behavior near the entanglement length,indicating the effects of entanglements under fast cooling conditions.The effect of chain length dispersity on crystallization becomes more obvious under fast cooling conditions.展开更多
Liquid cooling through a cold plate offers an efficient solution for battery thermal management.Excellent flow and heat transfer performance can be obtained by optimizing the flow channel structure of the cold plate u...Liquid cooling through a cold plate offers an efficient solution for battery thermal management.Excellent flow and heat transfer performance can be obtained by optimizing the flow channel structure of the cold plate using the topology optimization method.However,due to the uneven channel width of the optimized cold plate,there are some difficulties in processing,which affect its practical application in battery thermal management.In this study,the length scale control method is applied to a topology-optimized cold plate.An optimized cold plate considering length scale control is designed and processed,and its experimental results of flow and heat transfer are compared with those of a traditional cold plate and an optimized cold plate without length scale control.Results show that the relative deviations between the numerical and experimental results with length scale control are within 5%and 8%for temperature and pressure drop,respectively.The flow channel structure of the cold plate with length scale control is simpler and easier to process than that of the cold plate without length scale control.When the inlet velocity is 0.23 m/s,the maximum temperature,maximum temperature difference,and pressure drop of the cold plate with length scale control are 5.7 K,4.4 K,and 0.56 Pa lower than those of the traditional cold plate,respectively.This study provides valuable insights and practical guidance for the manufacturing and implementation of topology-optimized cold plates in battery thermal management systems.展开更多
The anchoring capacity of the anchor cable is closely related to the bonding length and radial pressure conditions.Through field pull-out tests,theoretical analysis,numerical simulation,and industrial tests,this study...The anchoring capacity of the anchor cable is closely related to the bonding length and radial pressure conditions.Through field pull-out tests,theoretical analysis,numerical simulation,and industrial tests,this study clarifies the relationship between radial pressure and bonding length for the ultimate pullout force and reveals the microscopic failure process of the resin-rock interface in the anchoring system.The results show that the ultimate load increases with the increase of bonding length in three different stages:rapid,slow,and uniform growth.The new mechanical model developed considering radial pressure describes the inverse relationship between radial pressure and the plastic zone on the bonding section,and quantifies the reinforcing effect of confining pressure on the anchoring force.During the pull-out process of the anchor cable,the generation of failure cracks is in the order of orifice,bottom,and middle of the hole.Radial pressure can effectively enhance the ultimate pull-out force,alleviate the oscillation increase of pull-out force,and inhibit resin cracking,but will produce an external crushing zone.It also reveals the synergistic effect between bonding length and radial pressure,and successfully carries out industrial tests of anchor cable support,which ensures the stability of the stope roof and provides an important reference for the design of anchor cable support in deep high-stress mines.展开更多
文摘Objective To identify risk factors contributing to prolonged postoperative length of stay(LOS)in very elderly patients following hip fracture surgery,with a focus on postoperative complications and the impact of different anesthesia approaches.Methods This retrospective single-center cohort study enrolled patients aged 90 years or older who underwent hip fracture surgery at Peking Union Medical College Hospital between January 31,2013 and December 31,2023.Relevant perioperative data were collected.The primary outcome was postoperative LOS,and the study cohort was divided into two groups:postoperative LOS≤7 days and LOS>7 days.Logistic regression was performed to identify factors related to prolonged postoperative LOS.Results A total of 155 patients were included.The average age was 92.7±2.6 years.There were 73(47%)patients with postoperative LOS>7 days.Postoperative pneumonia was the only factor associated with a prolonged postoperative LOS(OR=2.12,95%CI[1.09,4.16],P=0.028).Neither the type of anesthesia(regional vs.general anesthesia,OR=1.00,95%CI[0.53,1.90],P=0.993)nor the method of airway management(laryngeal mask ventilation vs.spontaneous breathing,OR=1.46,95%CI[0.58,3.76],P=0.424;endotracheal intubation vs.spontaneous breathing,OR=0.82,95%CI[0.39,1.69],P=0.592)showed a significant association with a prolonged postoperative LOS.Preoperative chronic obstructive pulmonary disease(OR=2.78,95%CI[1.05,7.65],P=0.040)and preoperative neutrophil count(OR=1.13,95%CI[1.01,1.26],P=0.029)were both significantly associated with the occurrence of postoperative pneumonia,while anesthesia type and airway management method were not.Conclusions Postoperative pneumonia was associated with prolonged postoperative LOS in very elderly patients undergoing hip fracture surgery,whereas anesthesia types and airway management methods show no association with prolonged postoperative LOS or postoperative pneumonia.Preoperative comorbidities,especially respiratory conditions and systemic inflammation,potentially play a substantial role in postoperative recovery.
基金Supported by the National Natural Science Foundation of China,No.81302124.
文摘BACKGROUND Red blood cell distribution width(RDW)is associated with the development and progression of various diseases.AIM To explore the association between pretreatment RDW and short-term outcomes after laparoscopic pancreatoduodenectomy(LPD).METHODS A total of 804 consecutive patients who underwent LPD at our hospital between March 2017 and November 2021 were retrospectively analyzed.Correlations between pretreatment RDW and clinicopathological characteristics and short-term outcomes were investigated.RESULTS Patients with higher pretreatment RDW were older,had higher Eastern Cooperative Oncology Group scores and were associated with poorer short-term outcomes than those with normal RDW.High pretreatment RDW was an independent risk factor for postoperative complications(POCs)(hazard ratio=2.973,95%confidence interval:2.032-4.350,P<0.001)and severe POCs of grade IIIa or higher(hazard ratio=3.138,95%confidence interval:2.042-4.824,P<0.001)based on the Clavien-Dino classification system.Subgroup analysis showed that high pretreatment RDW was an independent risk factor for Clavien-Dino classi-fication grade IIIb or higher POCs,a comprehensive complication index score≥26.2,severe postoperative pancreatic fistula,severe bile leakage and severe hemorrhage.High pretreatment RDW was positively associated with the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio and was negatively associated with albumin and the prognostic nutritional index.CONCLUSION Pretreatment RDW was a special parameter for patients who underwent LPD.It was associated with malnutrition,severe inflammatory status and poorer short-term outcomes.RDW could be a surrogate marker for nutritional and inflammatory status in identifying patients who were at high risk of developing POCs after LPD.
文摘To cater the need for real-time crack monitoring of infrastructural facilities,a CNN-regression model is proposed to directly estimate the crack properties from patches.RGB crack images and their corresponding masks obtained from a public dataset are cropped into patches of 256 square pixels that are classified with a pre-trained deep convolution neural network,the true positives are segmented,and crack properties are extracted using two different methods.The first method is primarily based on active contour models and level-set segmentation and the second method consists of the domain adaptation of a mathematical morphology-based method known as FIL-FINDER.A statistical test has been performed for the comparison of the stated methods and a database prepared with the more suitable method.An advanced convolution neural network-based multi-output regression model has been proposed which was trained with the prepared database and validated with the held-out dataset for the prediction of crack-length,crack-width,and width-uncertainty directly from input image patches.The pro-posed model has been tested on crack patches collected from different locations.Huber loss has been used to ensure the robustness of the proposed model selected from a set of 288 different variations of it.Additionally,an ablation study has been conducted on the top 3 models that demonstrated the influence of each network component on the pre-diction results.Finally,the best performing model HHc-X among the top 3 has been proposed that predicted crack properties which are in close agreement to the ground truths in the test data.
基金supported by the National Natural Science Foundation of China(12071444,12201581)the Fundamental Research Program of Shanxi Province of China(202103021223191).
文摘The minimal widths of three bounded subsets of the unit sphere associated to a unit vector in a normed linear space are studied,and three related geometric constants are introduced.New characterizations of inner product spaces are also presented.From the perspective of minimal width,strongε-symmetry of Birkhoff orthogonality is introduced,and its relation toε-symmetry of Birkhoff orthogonality is shown.Unlike most of the existing parameters of the underlying space,these new constants are full dimensional in nature.
文摘BACKGROUND Leg length discrepancy(LLD)following total hip arthroplasty(THA)is a common complaint,leading to decreased patient satisfaction.However,the effect of LLD before THA on outcomes and complications is not well defined.AIM To assess the effect of prior LLD on rates of falls,implant-related complications,stay length,readmissions,and implant survival following THA.METHODS A retrospective review of a nationwide insurance database was conducted from 2010 to 2021.All cases of THA and those with a prior diagnosis of LLD were identified.THA patients with LLD were matched to control patients 1:5 based on demographic and comorbidity profiles.Two-year fall rates and implant complications,lengths of stay,90-day readmissions,and time to revision were compared between cohorts.RESULTS A total of 2038 patients with LLD were matched to 10165 control patients.The LLD group showed significantly greater rates of falls[odds ratio(OR)=1.58;95%confidence interval(95%CI):1.24-2.01],dislocation(OR=2.61;95%CI:2.10-3.24),mechanical loosening(OR=4.58;95%CI:3.28-6.29),and periprosthetic fracture(OR=2.70;95%CI:1.96-3.72)compared to the control group(all P<0.001).Mean length of stay(LOS)was also significantly higher in the LLD group(3.1 days vs 2.8 days,P=0.034).No significant difference in 90-day readmission rates(7.75%vs 7.02%,P=0.244)was observed between the groups(P=0.244).Time to revision was significantly less in the LLD group(225 days vs 544 days,P<0.001).CONCLUSION LLD in patients having THA is related with significantly higher fall risk,rates of implant-related complications,LOS,and quicker time to revision.Identifying patients with LLD before their THA may help in identifying risks,better patient counselling,and more effective preoperative planning.However,the study have important limitations:Its design lacks information on the degree and cause of LLD,the time between diagnosis and surgery,and which leg with the discrepancy underwent the operation.Future well-designed studies should confirm the findings of this study.
基金supported by the National Natural Science Foundation of China(Grant Nos.12172017 and 11872083)Project of Beijing Municipal Education Commission(Grant Nos.KZ202210005006 and KZ202110005007).
文摘Intracranial aneurysm(IA)is a prevalent cerebrovascular disease associated with high mortality and disability rates upon rupture.The hemodynamics of IA,which are significantly influenced by geometric parameters,directly impact its rupture.This study focuses on investigating the transient flow characteristics in saccular IA models fabricated using a water droplet-based method,specifically examining the influence of neck widths.Particle image velocimetry technique and numerical simulation were employed to investigate the dynamic evolution of flow structures within three IA models.The results reveal that neck width(W)has a substantial effect on flow characteristics in the neck region,subsequently impacting the deep flow inside the sac.Three distinct patterns were observed during flow evolution inside the sac:for W=2 mm,two vortices occur and then disappear with relatively low average flow velocity;for W=4 mm,enhanced effects of a high-speed jet result in periodic pulsatile flow velocity distribution while maintaining stable vortex core position;for W=6 mm,significant changes in flow velocity occur due to size expansion and intensity increase of vortices.These findings demonstrate that neck widths play a complex role in influencing transient flow characteristics within IAs.Overall,this research contributes to further understanding transient flow behaviors in IAs.
文摘Objective:To explore the correlation between fetal foot length measured by ultrasound and gestational age.Methods:This study employed ultrasound to measure the fetal foot length,femoral length,and foot length/femoral length ratio in 214 pregnant women from 12 to 40 weeks of gestation,all of whom had no pregnancy complications or obstetric complications,and whose fetuses were normal.Results:A significant positive correlation was found between fetal foot length and gestational age(r=0.967,p<0.001);a similarly significant positive correlation was observed between fetal femoral length and gestational age(r=0.972,p<0.001);and a non-significant positive correlation was noted between the foot length/femoral length ratio and gestational age(r=0.943,p<0.001).Conclusion:Ultrasound can accurately measure fetal foot length and femoral length,both of which exhibit a significant positive correlation with gestational age,making them important reference indicators for assessing fetal growth and development.
基金Supported by Shaanxi Provincial Social Development Fund,No.2024SF-YBXM-140.
文摘BACKGROUND Post-hepatectomy liver failure(PHLF)after liver resection is one of the main complications causing postoperative death in patients with hepatocellular carcinoma(HCC).It is crucial to help clinicians identify potential high-risk PHLF patients as early as possible through preoperative evaluation.AIM To identify risk factors for PHLF and develop a prediction model.METHODS This study included 248 patients with HCC at The Second Affiliated Hospital of Air Force Medical University between January 2014 and December 2023;these patients were divided into a training group(n=164)and a validation group(n=84)via random sampling.The independent variables for the occurrence of PHLF were identified by univariate and multivariate analyses and visualized as nomograms.Ultimately,comparisons were made with traditional models via receiver operating characteristic(ROC)curves,calibration curves,and decision curve analysis(DCA).RESULTS In this study,portal vein width[odds ratio(OR)=1.603,95%CI:1.288-1.994,P≤0.001],the preoperative neutrophil-to-lymphocyte ratio(NLR)(OR=1.495,95%CI:1.126-1.984,P=0.005),and the albumin-bilirubin(ALBI)score(OR=8.868,95%CI:2.144-36.678,P=0.003)were independent risk factors for PHLF.A nomogram prediction model was developed using these factors.ROC and DCA analyses revealed that the predictive efficacy and clinical value of this model were better than those of traditional models.CONCLUSION A new Nomogram model for predicting PHLF in HCC patients was successfully established based on portal vein width,the NLR,and the ALBI score,which outperforms the traditional model.
文摘BACKGROUND As red blood cell distribution width(RDW)and albumin have been shown to be independent predictors of mortality from various diseases,this study aimed to investigate the effect of the RDW to albumin ratio(RA)as an independent predictor of the prognosis of patients admitted to the coronary care unit(CCU).AIM To use the RDW and albumin level to predict the prognosis of patients in the CCU.METHODS Data were obtained from the Medical Information Mart Intensive Care III database.The primary outcome was 365-day all-cause mortality,whereas the secondary outcomes were 30-and 90-day all-cause mortality,hospital length of stay(LOS),and CCU LOS.Cox proportional hazards regression model,propen-sity score matching,and receiver operating characteristic curve analyses were used.RESULTS The hazard ratio(95%confidence interval)of the upper tertile(RA>4.66)was 1.62(1.29 to 2.03)when compared with the reference(RA<3.84)in 365-day all-cause mortality.This trend persisted after adjusting for demographic and clinical variables in the propensity score-matching analysis.Similar trends were observed for the secondary outcomes of hospital and CCU LOS.Receiver operating characteristic curve analysis was performed by combining the RA and sequential organ failure assessment(SOFA)scores,and the C-statistic was higher than that of the SOFA scores(0.733 vs 0.702,P<0.001).CONCLUSION RA is an independent prognostic factor in patients admitted to the CCU.RA combined with the SOFA score can improve the predictive ability of the SOFA score.However,our results should be verified in future prospective studies.
基金supported by the National Natural Science Foundation of China(No.62273234)Key Research and Development Program of Shaanxi(Program No.2022GY-306)Technology Innovation Leading Program of Shaanxi(Program No.2022QFY01-16).
文摘Accurate prediction of strip width is a key factor related to the quality of hot rolling manufacture.Firstly,based on strip width formation mechanism model within strip rolling process,an improved width mechanism calculation model is delineated for the optimization of process parameters via the particle swarm optimization algorithm.Subsequently,a hybrid strip width prediction model is proposed by effectively combining the respective advantages of the improved mechanism model and the data-driven model.In acknowledgment of prerequisite for positive error in strip width prediction,an adaptive width error compensation algorithm is proposed.Finally,comparative simulation experiments are designed on the actual rolling dataset after completing data cleaning and feature engineering.The experimental results show that the hybrid prediction model proposed has superior precision and robustness compared with the improved mechanism model and the other eight common data-driven models and satisfies the needs of practical applications.Moreover,the hybrid model can realize the complementary advantages of the mechanism model and the data-driven model,effectively alleviating the problems of difficult to improve the accuracy of the mechanism model and poor interpretability of the data-driven model,which bears significant practical implications for the research of strip width control.
基金Supported by the Medical Science and Technology Project of Zhejiang Province of China(No.2020KY191).
文摘AIM:To investigate the ocular biological characteristics of children with myopia and rapid axial length(AL)changes prescribed spectacles with highly aspherical lenslets(HAL).METHODS:Data were collected from 156 children(252 eyes)with myopia and HAL treatment who were aged 7-13 and had rapid AL changes.The participants were divided into groups with AL reduction and elongation according to the changes in AL within 6mo.Paired t-tests were used to compare the ocular biological parameters at baseline and after rapid changes post-HAL treatment.Pearson’s correlation analysis was used to determine the association between the ocular parameters and AL changes.RESULTS:The ocular biological parameters significantly changed in the children with myopia and rapid AL changes after HAL treatment.In the group with AL reduction,the anterior chamber depth(ACD)and vitreous chamber depth(VCD)decreased.The crystalline lens thickness(CLT)increased,corneal flat keratometry(FK)decreased,and steep keratometry(SK)increased(all P<0.001).The eyes in the group with AL elongation had increased ACD and VCD and steepened SK,but the CLT or FK findings were not different.AL change was negatively associated with baseline astigmatism(r=-0.171;P=0.007).CONCLUSION:In the eyes with HAL treatment,decreased ACD and VCD,thickened CLT,flattened FK,and steepened SK are observed during AL reduction.Lower baseline astigmatism is associated with AL reduction.The AL reduction may suggest the potential efficacy of HAL intervention in myopia control,while providing evidence for optimizing personalized myopia management strategies.Further longitudinal studies are warranted to validate whether rapid AL changes predict sustained treatment efficacy.
文摘AIM:To evaluate the efficacy of the Tecnis Symfony ZXR00 lens in achieving optimal visual outcomes for cataract surgery patients with axial length(AL)shorter than 24 mm.METHODS:A total of 21 subjects(37 eyes)were submitted to cataract surgery and implantation of Tecnis Symfony ZXR00 lens(Johnson&Johnson Vision)was assessed.Patients were examined at 5 m,80 cm,and 40 cm for uncorrected distance visual acuity(UCDVA)and corrected distance visual acuity(CDVA),uncorrected intermediate(UCIVA),and uncorrected near visual acuity(UCNVA).Further,based on the optimal distance correction,the monocular defocusing curve in the range of+0.5 to-3.5 D was investigated.A simple patient-reported spectacle independence questionnaire(PRSIQ)was used to evaluate subjects’subjective feelings about their dependence on glasses at various distances.Multiple linear regression was employed to examine the association amony intraocular lenses(IOLs)diopter,AL,corneal curvature,anterior chamber depth,mean manifest refractive spherical equivalent,pupil,pupil/scan,target refraction,and near vision(logMAR).RESULTS:The study demonstrated enhanced UCNVA alongside comparable distant vision and UCIVA outcomes in eyes with AL shorter than 24 mm.Mean post-operative UCDVA significantly improved from preoperative levels 0.530±0.406(P=0.000).Notably,83.3%of eyes achieved 0.01 logMAR in UCNVA.Five unilateral cases with blended IOL implantation also showed satisfactory visual acuity and satisfaction.The 90.5%(19/21)achieved spectacle independence.The average score for self-reported spectacle-independence on the PRSIQ was 3.52 with a standard deviation of 0.98.The results of the regression analysis revealed that one predictor,the pupil/scan accounted for 27.6%of the variation in near vision[logMAR;F(1,35)=13.33,P<0.01].CONCLUSION:The results affirm the effectiveness of the Tecnis Symfony ZXR00 lens in enhancing visual outcomes for cataract surgery patients with AL shorter than 24 mm.Additionally,the pupil/scan emerges as a critical factor influencing postoperative near vision.
基金Project supported by the National Natural Science Foundation of China(Grant No.61875148)the Key Awards Program of Cultivating Outstanding Innovative Postgraduates in Arts and Sciences of Tianjin University(Grant No.C1-2022002)+3 种基金the Talent Project of Anhui Science and Technology University(Grant No.DQYJ202304)the University-Level Research Project of Tianjin Sino-German University of Applied Sciences(Grant No.zdkt2018-007)China Association for Science and Technology Young Talent Support Project Doctoral Special Programthe National High-level University Scholarship Program for Graduate Students of China Scholarship Council(Grant No.202406250166)。
文摘We report an interesting and abnormal electromagnetic phenomenon with regard to a terajet(TJ)that is generated in a reflection mode,which is realized by placing a dielectric scatterer onto a metal reflection plate.We show that the introduction of an air hollow into metal reflection plate beneath the scatterer does not induce an expected decrease but an abnormal increase of focal length of the TJ by as much as more than three times.This abnormal phenomenon takes place in case that the air hollow is shallow and there exists a critical hollow depth for a given lateral size of air hollow.Larger than the critical depth,the phenomenon no longer occurs.It is explained from viewpoints of both ray optics in terms of role of relative portion of central waves in TJ formation and electromagnetic field theory with regard to hollow-induced phase singularities.
基金supported by STI 2030-Major Project(2023ZD04069)the National Natural Science Foundation of China(32472129,U24A20392,32201841)+1 种基金Regional Joint Youth Fund for Basic and Applied Basic Research Foundation of Guangdong Province(2022 A1515110454)Science and Technology Projects in Guangzhou(2023B03J1355).
文摘Grain size is a crucial factor influencing both rice yield and appearance quality.In this study,we identified GL6.1 as a gene associated with rice grain size by map-based cloning.The GL6.1 encodes a protein with CC-NB-LRR domain,a structural motif related to rice disease resistance.Genetic transformation experiments and the construction of gene pyramiding lines indicate that GL6.1 functions as a negative regulatory factor for rice grain length.By the analysis of SSSLs with diverse donor parents,a total of 11 single nucleotide polymorphisms(SNPs)are identified that are closely associated with the phenotype variations.A yeast one-hybrid library screening revealed that GL6.1 interacts with OsWRKY53,a transcription factor associated with rice disease resistance.Furthermore,RNA-seq assay also revealed the involvement of pathways associated with disease resistance,hinting at a multifaceted role for GL6.1 in both yield and stress tolerance traits in rice.These results indicate that the cloning and in-depth studies of GL6.1 would provide valuable insights into the interplay among high yield,superior quality,and stress tolerance,which are critical goals for rice breeding.
基金Project supported by the Key Research and Development Plan of Xinjiang Uygur Autonomous Region,China(Grant Nos.2022B01040 and 2022B01040-2)the Key Project of Heilongjiang Natural Science Foundation(Grant No.ZD2021F002)。
文摘A self-pulsed Tm:GdScO_(3)laser was experimentally demonstrated by using a compact linear resonant cavity.When the pump power was 19.6 W,an average output power of 1771 m W was achieved from the self-pulsed Tm:GdScO_(3)laser with a pulse width of 158.1 ns and a pulse repetition frequency of 112.8 kHz,corresponding to an optical-to-optical conversion efficiency of 9.0%.Moreover,a single pulse energy of 15.7μJ and a pulse peak power of 99.3 W were acquired from the self-pulsed Tm:GdScO_(3)laser.This is,as we know,the first time that the self-pulsed laser output at 2-μm waveband range was obtained by utilizing a Tm:GdScO_(3)crystal so far.
基金Supported by Wu Jieping Medical Foundation(No.320.6750.2021-4-15).
文摘AIM:To compare the effects of different types of negative pressure suction on the macular and optic disc retinal vessel density(VD)in myopic patients with different axial lengths(ALs)undergoing femtosecond laser-assisted excimer laser in situ keratomileusis(FS-LASIK)by optical coherence tomography angiography(OCTA).METHODS:A prospective,nonrandomized,controlled study.Participants underwent FS-LASIK surgery were divided into the short AL group(SAL,22≤AL<26 mm)and the long AL group(LAL,26≤AL<28 mm)according to the different ALs.Further,the two groups were divided into subgroups according to the corneal flap using VisuMax or WaveLight FS200 femtosecond laser(FS)platform.All patients underwent OCTA before the surgery and 1-day/1-week/1-month after the surgery.ANOVA statistically analyzed data with two-factor repeated measurement in SPSS.RESULTS:Totally 108 participants(108 eyes,18–35y)were divided into SAL group[22 patients(4 males and 18 females)were treated with VisuMax,and 24(3 males and 21 females)were treated with WaveLight FS200]and LAL group[34 patients(4 males and 30 females)were treated with VisuMax,and 28 patients(6 males and 22 females)were treated with WaveLight FS200].In the LAL group,there was no significant difference in macular superficial capillary plexuses vessel density(SCP-VD)in the fovea and perifovea region,but compared with the VisuMax subgroup,SCP-VD in the parafoveal region(t=2.647,P=0.010)and the whole area(t=2.030,P=0.047)in WaveLight FS200 subgroup decreased at one day after the operation and increased to a preoperative level at 1-week and 1-month after operation.There was no significant difference between SCP-VD in the two SAL subgroups,neither of deep capillary plexuses vessel density(DCP-VD)and optic nerve head vessel density(ONH-VD)in the SAL and LAL groups.CONCLUSION:With the increase of AL and suction intensity,a transient decrease of SCP-VD in the macular region is observed at 1d postoperatively during FS-LASIK,and it increases to preoperative level at 1-week and 1-month postoperatively.However,the AL and suction intensity do not affect the macular DCP-VD and ONH-VD.
基金National Natural Science Foundation of China No.22341302.
文摘The crystallization behavior of polymers is significantly influenced by molecular chain length and the dispersion of varying chain lengths.The complexity of studying crystallization arises from the dispersity of polymer materials and the typically slow cooling rates.Recent advancements in fast cooling techniques have rendered the investigation of polymer crystallization at varying cooling rates an attractive area of research;however,a systematic quantitative framework for this process is still lacking.We employ a coarse-grained model for polyvinyl alcohol(CGPVA)in molecular dynamics simulations to study the crystallization of linear polymers with varying chain lengths under variable cooling rates.Monodisperse,bidisperse and polydisperse samples are simulated.We propose two formulae based on a two-phase assumption to fit the exothermal curves obtained during cooling.Based on these formulae,better estimations of crystallization temperatures are obtained and the effects of chain lengths and cooling rates are studied.It is found that the crystallization temperature increases with chain length,similar to the Gibbs-Thomson relation formelting temperature,indicating a strong relation between fast crystallization and glass formation in linear polymers.Extrapolation to the infinitely slow cooling rate provides an easy way in simulations to estimate the equilibrium crystallization temperature.The effective chain lengths of polydisperse and bidisperse samples are found to be the number-averaged chain lengths compared to the weight-averaged ones.The chain length-dependent crystallization exhibits crossover behavior near the entanglement length,indicating the effects of entanglements under fast cooling conditions.The effect of chain length dispersity on crystallization becomes more obvious under fast cooling conditions.
基金supported by the National Natural Science Foundation of China(No.52206271)Guangxi Science and Technology Major Program(GK-AA23062070)+2 种基金the National Natural Science Foundation of China(No.52306266)the Key Project of Natural Science Funds of Tianjin City(No.24JCZDJC01060)funded by the Key Laboratory of Shallow Geothermal Energy,Ministry of Natural Resources of the People’s Republic of China(No.KLSGE202401-04).
文摘Liquid cooling through a cold plate offers an efficient solution for battery thermal management.Excellent flow and heat transfer performance can be obtained by optimizing the flow channel structure of the cold plate using the topology optimization method.However,due to the uneven channel width of the optimized cold plate,there are some difficulties in processing,which affect its practical application in battery thermal management.In this study,the length scale control method is applied to a topology-optimized cold plate.An optimized cold plate considering length scale control is designed and processed,and its experimental results of flow and heat transfer are compared with those of a traditional cold plate and an optimized cold plate without length scale control.Results show that the relative deviations between the numerical and experimental results with length scale control are within 5%and 8%for temperature and pressure drop,respectively.The flow channel structure of the cold plate with length scale control is simpler and easier to process than that of the cold plate without length scale control.When the inlet velocity is 0.23 m/s,the maximum temperature,maximum temperature difference,and pressure drop of the cold plate with length scale control are 5.7 K,4.4 K,and 0.56 Pa lower than those of the traditional cold plate,respectively.This study provides valuable insights and practical guidance for the manufacturing and implementation of topology-optimized cold plates in battery thermal management systems.
基金Financial supports for this work,provided by the National Natural Science Foundation Project of China(No.52374152)the Guangxi Science and Technology Plan Project of China(No.2022AB31023)the National Basic Research Development Program of China(No.2022YFC2904602)are gratefully acknowledged。
文摘The anchoring capacity of the anchor cable is closely related to the bonding length and radial pressure conditions.Through field pull-out tests,theoretical analysis,numerical simulation,and industrial tests,this study clarifies the relationship between radial pressure and bonding length for the ultimate pullout force and reveals the microscopic failure process of the resin-rock interface in the anchoring system.The results show that the ultimate load increases with the increase of bonding length in three different stages:rapid,slow,and uniform growth.The new mechanical model developed considering radial pressure describes the inverse relationship between radial pressure and the plastic zone on the bonding section,and quantifies the reinforcing effect of confining pressure on the anchoring force.During the pull-out process of the anchor cable,the generation of failure cracks is in the order of orifice,bottom,and middle of the hole.Radial pressure can effectively enhance the ultimate pull-out force,alleviate the oscillation increase of pull-out force,and inhibit resin cracking,but will produce an external crushing zone.It also reveals the synergistic effect between bonding length and radial pressure,and successfully carries out industrial tests of anchor cable support,which ensures the stability of the stope roof and provides an important reference for the design of anchor cable support in deep high-stress mines.