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A Study on‘the Market for Lemons’and the Strategy of‘Unification’in Booking Systems:A Case Study on the FAHSYSU Simulation T System of the Training Center for Clinical Skills of the First Affiliated Hospital of Sun Yat-sen University
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作者 Yiyan Dai 《Modern Electronic Technology》 2022年第2期9-16,共8页
Based on the blueprint of the training center for clinical skills of our hospital,this paper discusses the effect of‘the market for lemons’in its booking system from the perspective of economics of information,uses ... Based on the blueprint of the training center for clinical skills of our hospital,this paper discusses the effect of‘the market for lemons’in its booking system from the perspective of economics of information,uses the law of large numbers and the central limit theorem to model to carry out the case study of FAHSYSU Simulation T,and takes measures of offsetting adverse selections to increase booking efficiency.The paper also analyzes how to apply the ancient Chinese theory that man is an integral part of nature to wipe out‘the market for lemons’. 展开更多
关键词 Information asymmetry The market for lemons Akalov mode Adverse selection TAO
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基于分子感官技术解析‘广东香水’柠檬香气品质 被引量:1
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作者 张思凝 张兴蕊 +9 位作者 吴东轩 康婧博 陈晓琳 耿丽君 殷光敏 陈嘉景 高俊燕 蔡中虎 刘园 徐娟 《中国农业科学》 北大核心 2025年第1期141-155,I0008-I0010,共18页
【目的】以‘广东香水’柠檬为原料制作的茶饮深受消费者喜爱,但其果实香气轮廓、主要香气活性成分及生物合成关键基因尚需解析。本研究采用代谢组学结合感官评价的分子感官技术对‘广东香水’柠檬香气品质形成的物质基础及关键基因进... 【目的】以‘广东香水’柠檬为原料制作的茶饮深受消费者喜爱,但其果实香气轮廓、主要香气活性成分及生物合成关键基因尚需解析。本研究采用代谢组学结合感官评价的分子感官技术对‘广东香水’柠檬香气品质形成的物质基础及关键基因进行探究,为‘广东香水’柠檬香气品质研究奠定基础。【方法】使用GC-MS对云南巍山、广东云浮及广西梧州3个不同产地的‘广东香水’柠檬挥发性物质进行检测,并组织感官评价小组对不同产地样品香气品质进行评估。利用气相色谱-嗅闻-质谱联用(GC/O-MS)结合香气提取物稀释分析(AEDA)、香气活性值(OAV)分析和香气重构的方法对‘广东香水’柠檬香气活性物质进行鉴定,进一步确定其特征香气化合物。并基于基因家族分析,挖掘呈香物质合成相关基因。【结果】在‘广东香水’柠檬的黄皮层、果肉和切片中分别鉴定到了40、21和33种挥发性物质,黄皮层、果肉组织中含量最高的样品分别来自云南巍山、广东云浮。香气感官属性方面,来自云南巍山和广东云浮的‘广东香水’柠檬切片香气强度显著高于广西梧州的样品,更受消费者喜爱;而广西梧州的样品整果香气品质比其他地区样品更佳。采用溶剂辅助风味蒸馏萃取(SAFE)等方法对云南巍山‘广东香水’柠檬的精油进行了提取,在‘广东香水’柠檬精油中共鉴定出25种香气活性物质,结合OAV分析和香气重构试验,进一步确定香茅醛和柠檬醛是其特征香气化合物,并构建其香气风味轮。基于保守结构域鉴定和Blast比对,在‘广东香水’柠檬基因组中鉴定到52个可能参与呈香物质合成的萜烯合酶(TPS)基因。【结论】挥发性物质谱和感官评价表明云南巍山的‘广东香水’柠檬切片香气品质较优,以该地区样品为研究材料,共鉴定到25种香气活性物质,其中香茅醛和柠檬醛为‘广东香水’柠檬的特征香气化合物,d-柠檬烯为其提供背景香味。结合定量描述性分析和GC/O-MS收集的气味特性,构建了以“果香”“木香”“药香”“辛香”“花香”和“青草味”6大类包含15个香气描述词的‘广东香水’柠檬香气风味轮,挖掘到可能参与呈香物质合成的52个TPS基因。 展开更多
关键词 ‘广东香水’柠檬(Citrusmedica Guangdongxiangshui lemon) 感官评价 特征香气化合物 香气风味轮 萜烯合酶基因
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Genome-wide analysis of the S-phase kinase-association protein1(ClSKP1) family and the role of S-RNase targeting by an SCF(Cullin1-SKP1-F-box) complex in the self-incompatibility of‘Xiangshui' lemon 被引量:1
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作者 Yuze Li Wei Lin +9 位作者 Jiawei Zhu Moying Lan Cong Luo Yili Zhang Rongzhen Liang Liming Xia Wangli Hu Xiao Mo Guixiang Huang Xinhua He 《Horticultural Plant Journal》 2025年第2期593-607,共15页
The SKP1 gene is an important component of the SCF(SKP1-Cullin1-F-box)complex and serves as a bridge connecting the F-box and Cullin1genes(F-box-SKP1-Cullin1).The pattern of S-RNase being ubiquitously labelled by the ... The SKP1 gene is an important component of the SCF(SKP1-Cullin1-F-box)complex and serves as a bridge connecting the F-box and Cullin1genes(F-box-SKP1-Cullin1).The pattern of S-RNase being ubiquitously labelled by the SCF complex and degraded by the 26S protease accounts for the bulk of the available self-incompatibility studies.In this study,15 ClSKP1s from the‘Xiangshui'lemon genome and ubiquitome exist in the same SKP1 conserved domain(CD)as SKP1s in other species.The q PCR results showed that SKP1-6 and SKP1-14 have tissue expression patterns specific for expression in pollen.In addition,SKP1-6 and SKP1-14 in the stigma,style and ovary were significantly upregulated after self-pollination compared to those after cross-pollination.A subcellular location showed that SKP1-6 and SKP1-14 were located in the nucleus.In addition,yeast two-hybrid(Y2H)assays,bimolecular fluorescence complementation(BiFC)and luciferase complementation imaging(LCI)assays showed that SKP1-6 interacted with F-box1,F-box33,F-box34,F-box17,F-box19,Cullin1-2 and 26S proteasome subunit 4 homolog A(26S PS4HA).SKP1-14 interacted with F-box17,F-box19,F-box35,Cullin1-2 and 26S PS4HA.The interaction of Cullin1-2 and the F-box with SKP1 as a bridge was verified by a yeast three-hybrid experiment.The ability of S3-RNase to inhibit pollen and pollen tube growth and development was assessed using in vitro pollen co-culture experiments with recombinant S3-RNase proteins.Overall,this study provides important experimental evidence and theoretical basis for understanding the mechanism of self-incompatibility in plants by revealing the key role of the SCF complex in‘Xiangshui'lemon,which is bridged by ClSKP1-6,in self-incompatibility.The results of this study are of great significance for the future indepth exploration of the molecular mechanism of the SCF complex and its wide application in the self-incompatibility of plants. 展开更多
关键词 LEMON SKP1 SCF SELF-INCOMPATIBILITY Expression analysis Functional analysis
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Convenient and highly efficient adsorption of diosmetin from lemon peel by magnetic surface molecularly imprinted polymers 被引量:1
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作者 Dongliang Xie Yi Kuang +12 位作者 Bingnan Yuan Yunlong Zhang Chenyu Ye Yuyi Guo Hua Qiu Juanna Ren Saud O.Alshammari Qamar A.Alshammari Zeinhom M.El-Bahy Kui Zhao Zhanhu Guo Qingqing Rao Shengxiang Yang 《Journal of Materials Science & Technology》 2025年第8期159-170,共12页
As a typical bioflavonoid,diosmetin is desirable in the field of natural medicine,healthy food,and cosmetics by anti-cancer,antibacterial,antioxidant,estrogen-like and anti-inflammatory activities,and it comes from a ... As a typical bioflavonoid,diosmetin is desirable in the field of natural medicine,healthy food,and cosmetics by anti-cancer,antibacterial,antioxidant,estrogen-like and anti-inflammatory activities,and it comes from a wide range of sources in traditional Chinese medicine like spider fragrance,spearmint and chrysanthemum,as well as in Citrus fruit.However,traditional analytical methods such as silica gel column chromatography face multiple challenges in the selective extraction of diosmetin from biological materials and traditional Chinese medicinal materials.Therefore,it is urgent to develop a new type of absorbent with high efficiency,recyclability and good specificity to diosmetin.In this investigation,a magnetic surface molecularly imprinted polymer(labeled as Diosmetin/SMIPs)was synthesized employing magnetic nanoparticles as the carrier and 4-vinylpyridinyl(4-VP)as the functional monomer by surface imprinting technology.The functional monomer was screened by the binding energy(△E)between functional monomers and template molecules via computational simulation.The Diosmetin/SMIPs had a high level of specific recognition and adsorption capability towards diosmetin with a 20.25 mg g^(-1) adsorption capacity and an imprinting factor(IF)of 2.28.Additionally,it demonstrated excellent regeneration performance with 8 adsorption/desorption cycles.In addition,91.20%-94.16% of spiked diosmetin was recovered from the lemon peel samples.The strategy of constructing Diosmetin/SMIPs based on computational simulation can effectively enhance the specific adsorption performance of diosmetin.Meanwhile,Diosmetin/SMIPs synthesized by imprinting polymerization showed excellent anti-interference and reusability,and realized efficient targeted extraction of diosmetin from lemon peel samples.The results of this investigation provide a promising adsorbent for selective enrichment of diosmetin from Citrus fruit and complicated materials. 展开更多
关键词 Diosmetin Selective extraction Magnetic molecularly imprinted polymer Lemon peel
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巴斯夫与LEMON签署合作备忘录,共同开发新型服装材料解决方案
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《上海塑料》 2025年第5期64-64,共1页
2025年10月16日,巴斯夫与LEMON株式会社在韩国首尔签署谅解备忘录,双方将携手运用巴斯夫Elastollan^(Ⓡ)热塑性聚氨酯(TPU)制成的Freeflex^(Ⓡ)纤维,共同推进新型服装应用解决方案。作为功能性纳米膜的领先生产商,LEMON计划将Freeflex应... 2025年10月16日,巴斯夫与LEMON株式会社在韩国首尔签署谅解备忘录,双方将携手运用巴斯夫Elastollan^(Ⓡ)热塑性聚氨酯(TPU)制成的Freeflex^(Ⓡ)纤维,共同推进新型服装应用解决方案。作为功能性纳米膜的领先生产商,LEMON计划将Freeflex应用于其防水防风服装的生产中。该备忘录还明确了双方在技术开发与业务拓展方面的未来合作机会。Freeflex是一款巴斯夫的高性能材料,专为通过静电纺丝工艺制造具有网状结构的纳米膜而设计。它具备优异防水性能、良好的透气性,并且质地轻盈。同时该材料专为在极端环境条件下使用设计,能有效保持舒适性与耐用性。 展开更多
关键词 Freeflex 新型服装材料 LEMON 巴斯夫 合作备忘录
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Development of Lemon-Flavored Solid Instant Tea
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作者 Yan WANG Yikang FENG Lei PENG 《Medicinal Plant》 2025年第1期30-34,共5页
[Objectives]To investigate the optimal preparation process for lemon-flavored solid instant tea.[Methods]The formulation process was optimized through a single-factor combined orthogonal test,utilizing large-leaf Pu&#... [Objectives]To investigate the optimal preparation process for lemon-flavored solid instant tea.[Methods]The formulation process was optimized through a single-factor combined orthogonal test,utilizing large-leaf Pu'er tea as the primary raw material and perfume lemon as the auxiliary ingredient.Sensory scores and the effectiveness of the spray drying process served as the key indicators for this investigation.[Results]The optimal formulation for lemon-flavored solid instant tea was established as follows:15 g of Pu'er tea,25 g of perfume lemon,a solid-liquid ratio of 1:20(g/mL),an extraction temperature of 90℃,an extraction duration of 30 min,and air inlet and outlet temperatures of 200℃and 80℃,respectively.This formulation produced the most favorable flavor profile for the perfume lemon-flavored solid instant tea,which was characterized by a stable texture and a sensory evaluation score of 91.97 points.[Conclusions]This study has the potential to enhance the development and utilization of large-leaf Pu'er tea and perfume lemon resources. 展开更多
关键词 Large-leaf Pu'er tea Instant tea Spray drying Perfume lemon
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巴斯夫与LEMON株式会社合作开发Freeflex^(®)纤维膜
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作者 钱伯章 《合成纤维工业》 2025年第6期9-9,共1页
2025年10月17日,巴斯夫公司与LEMON株式会社签署谅解备忘录,双方将基于巴斯夫公司生产的Elastollan^(®)热塑性聚氨酯(TPU)合作开发Freeflex^(®)纤维膜,共同推进新型服装应用解决方案。作为功能性纳米膜的领先生产商,LEMON株... 2025年10月17日,巴斯夫公司与LEMON株式会社签署谅解备忘录,双方将基于巴斯夫公司生产的Elastollan^(®)热塑性聚氨酯(TPU)合作开发Freeflex^(®)纤维膜,共同推进新型服装应用解决方案。作为功能性纳米膜的领先生产商,LEMON株式会社计划将Freeflex^(®)纤维膜应用于其防水防风服装产品中。 展开更多
关键词 谅解备忘录 ELASTOLLAN LEMON株式会社 巴斯夫 热塑性聚氨酯
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Oxygen heterocyclic compounds(OHCs)in lemon oils are important markers in targeted HPLC analyses for authentication
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作者 Siyu Liu Shiming Li Chi-Tang Ho 《Food Science and Human Wellness》 2025年第2期421-428,共8页
Lemon oils are broadly used as flavoring agents in beverages,foods,cosmetics and pharmaceuticals,yet the adulteration of natural,particularly cold pressed lemon oils is very common in the industry due to its unmet dem... Lemon oils are broadly used as flavoring agents in beverages,foods,cosmetics and pharmaceuticals,yet the adulteration of natural,particularly cold pressed lemon oils is very common in the industry due to its unmet demand and high cost.Nowadays,most quality control(QC)analysis of lemon oils is conducted by gas chromatography(GC)analysis,which is far from a reliable method.Oxygen heterocyclic compounds(OHCs)in non-volatile fraction are gaining increasing attention in authentication process because of the nearly finger-printing profiles of OHCs in cold pressed citrus essential oils.Our goal in this study was to identify OHCs using high performance liquid chromatography(HPLC)in lemon oils,establish OHC profiles,perform stepwise logistic regression analysis(SLRA)and build effective predicting model and further determine adulterated lemon oils by referencing the OHC profiles and established models.After HPLC analyses,profiling and SLRA modeling of 154 OHCs samples of industrial lemon oils,we found that the combination of isopimpinellin and total OHC concentration are essential and robust predictors to differentiate authentic samples from adulterated lemon oils with a success rate of 98%from the 5-fold cross validation.This study provided a reliable and efficient method in determining the authenticity of lemon oils. 展开更多
关键词 Lemon oils Oxygen heterocyclic compounds High performance liquid chromatography(HPLC) AUTHENTICITY Targeted analysis Quality control
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LEMON法预测困难气道的有效性 被引量:3
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作者 徐德朋 杨磊 +5 位作者 王超 杨蔷 文晓兵 周文 张燕燕 江学成 《临床麻醉学杂志》 CAS CSCD 北大核心 2016年第12期1215-1217,共3页
困难气道是麻醉中常遇到的紧迫而危险的境况,许多严重麻醉并发症和死亡的发生由困难气道管理失当引起^([1-3])。对未预料的困难气道,后果更为严重。虽然可视喉镜的应用使气管插管变得容易,插管困难的发生率也明显降低^([1^4]),但对... 困难气道是麻醉中常遇到的紧迫而危险的境况,许多严重麻醉并发症和死亡的发生由困难气道管理失当引起^([1-3])。对未预料的困难气道,后果更为严重。虽然可视喉镜的应用使气管插管变得容易,插管困难的发生率也明显降低^([1^4]),但对全麻患者气道评估和对困难气道的处理是麻醉医师的临床基本技能,需要熟练掌握和应用,况且传统喉镜仍为目前的主要工具。 展开更多
关键词 LEMON 临床基本技能 麻醉并发症 肋间神经阻滞 气管插管 插管困难 麻醉起效时间 麻醉维持时间 椎管内麻醉 镇痛持续时间
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香蜂草精油的药理与应用研究概况 被引量:2
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作者 申万祥 荆颖艾莎 +5 位作者 赵兵 李文燕 陈国权 刘向辉 巩江 倪士峰 《安徽农业科学》 CAS 2012年第31期15191-15193,共3页
香蜂草为唇形科著名草药,具有极高的保健和医疗价值。近年来研究表明,其精油具有镇静、驱风、解痉、抗菌、抗病毒、抗真菌、抗炎、抗氧化和改善血糖耐受水平等多种功能。而且,其在许多国家的不同工业部门(如医药、香水、化妆品和食品等... 香蜂草为唇形科著名草药,具有极高的保健和医疗价值。近年来研究表明,其精油具有镇静、驱风、解痉、抗菌、抗病毒、抗真菌、抗炎、抗氧化和改善血糖耐受水平等多种功能。而且,其在许多国家的不同工业部门(如医药、香水、化妆品和食品等)均得到了广泛应用。该文在广泛文献检索的基础上,概述了香蜂草精油的活性成分、药理作用和医药应用,为深入开发应用提供了依据。 展开更多
关键词 香蜂草(Lemon Balm) 挥发油 药理作用 医药应用
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超声测量联合LEMON法在阻塞性睡眠呼吸暂停低通气综合征患者困难气道评估中的应用研究
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作者 陈以建 周文 李以平 《赣南医学院学报》 2023年第12期1250-1254,共5页
目的:分析使用超声测量联合LEMON法评估阻塞性睡眠呼吸暂停低通气综合征(Obstructive sleep apnea hypopnea syndrome,OSAHS)患者困难气道的准确性。方法:选择择期全麻气管插管下行改良腭咽成形术OSAHS患者46例,根据插管时Cormack-Lehan... 目的:分析使用超声测量联合LEMON法评估阻塞性睡眠呼吸暂停低通气综合征(Obstructive sleep apnea hypopnea syndrome,OSAHS)患者困难气道的准确性。方法:选择择期全麻气管插管下行改良腭咽成形术OSAHS患者46例,根据插管时Cormack-Lehane分级分为两组:Ⅰ、Ⅱ级为非喉镜暴露困难组27例,Ⅲ、Ⅳ级为喉镜暴露困难组19例。麻醉前测量张口度、甲颏距离,评估改良Mallampati分级,患者麻醉后在相同体位下行气管插管。比较常规评估气道方法和超声测量联合LEMON法与喉镜显露困难的关系,采用受试者工作特征曲线(Receiver operating characteristic curve,ROC)分析各指标预测困难气道的效能。结果:喉镜暴露困难组超声测量数据、LEMON法评分、改良Mallampati分级高于非喉镜暴露困难组(P<0.05)。超声测量联合LEMON法的曲线下面积(Area under curve,AUC)为0.990(95%CI 0.969~1.000),高于单独应用超声测量或LEMON法的AUC值。结论:超声测量和LEMON法均可有效对OSAHS患者困难气道进行评估,其中超声测量预测OSAHS患者困难气道具有较好的效果,超声测量联合使用LEMON法可提高评估OSAHS患者困难气道的准确性。 展开更多
关键词 超声测量 LEMON法 睡眠呼吸暂停 阻塞性 气道评估 困难气道
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LEMON法预测患者困难气道的临床效果 被引量:10
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作者 杨芳芳 王茗芳 +4 位作者 王斌 徐建玲 钱美平 姚卫东 金孝岠 《临床麻醉学杂志》 CAS CSCD 北大核心 2018年第4期331-335,共5页
目的评价LEMON法预测困难气道的临床效果。方法选择择期行全身麻醉下喉镜暴露气管插管的手术患者1 528例,男680例,女848例,年龄18~83岁,ASAⅠ或Ⅱ级。麻醉前进行LEMON法评分,采用受试者工作特征曲线(receiver operating characteristic ... 目的评价LEMON法预测困难气道的临床效果。方法选择择期行全身麻醉下喉镜暴露气管插管的手术患者1 528例,男680例,女848例,年龄18~83岁,ASAⅠ或Ⅱ级。麻醉前进行LEMON法评分,采用受试者工作特征曲线(receiver operating characteristic curve,ROC)及曲线下面积(area under the curve,AUC)评价LEMON法预测困难气道的临床效果。结果困难气管插管患者37例,发生率为2.4%。困难喉镜暴露患者106例,发生率为6.9%。LEMON法预测困难喉镜暴露及困难气管插管的AUC分别为0.884(95%CI 0.867~0.899)和0.934(95%CI 0.921~0.946)。结论LEMON法在患者困难气道预测中有较好的临床效果。 展开更多
关键词 气道评估 全身麻醉 困难喉镜暴露 困难气管插管 LEMON法
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品尝水果 品味习语
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作者 喻劲梅 《英语自学》 2005年第5期33-33,共1页
关键词 苹果派 LEMON 特洛伊战争 英语俚语 水果味 SQUEEZE 又香 金玉其外 JUICE 中有
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情感语言资源语义互操作模型研究
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作者 严骏 《信息与电脑》 2016年第19期37-38,共2页
情感分析强烈依赖语言资源,尤其与情感词典有直接关系,而这些情感词典等语言资源通常是分散的、异构的,并且局限于某个特定领域。笔者提出一种模型,旨在:(1)为情感分析构建一个通用语言资源表达模型,为基于已形成的关联数据格式(Lemon、... 情感分析强烈依赖语言资源,尤其与情感词典有直接关系,而这些情感词典等语言资源通常是分散的、异构的,并且局限于某个特定领域。笔者提出一种模型,旨在:(1)为情感分析构建一个通用语言资源表达模型,为基于已形成的关联数据格式(Lemon、Marl、NIF、ONYX)的情感分析及服务建立APIs;(2)建立一个语言资源池,用互操作的方式使得分散的语言资源及服务能在情感分析中可用。笔者描述了资源池中可用的语言资源及服务,并列举了几个基于资源池的实例应用。 展开更多
关键词 情感本体 本体 NIF LEMON MARL
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输出假设理论指导下的多模态lemon英语写作教学体系初探
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作者 张琳娜 《湖北函授大学学报》 2014年第4期128-129,共2页
本文给出输出假设理论指导下的多模态lemon英语写作教学体系的定义,简述国内外的研究情况,分析研究的必要性,分析研究的意义和创新之处,给出研究的方法和具体的教学环节,对创新理论,丰富外语教学方法和提高学生的写作水平有重要的指导... 本文给出输出假设理论指导下的多模态lemon英语写作教学体系的定义,简述国内外的研究情况,分析研究的必要性,分析研究的意义和创新之处,给出研究的方法和具体的教学环节,对创新理论,丰富外语教学方法和提高学生的写作水平有重要的指导意义。 展开更多
关键词 输出假设理论 多模态 lemon教学环节
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Agrobacterium-Mediated Transfer of Arabidopsis ICE1 Gene into Lemon (Citrus Limon (L.) Burm. F. cv. Eureka) 被引量:11
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作者 HUANG Jia-quan SUN Zhong-hai 《Agricultural Sciences in China》 CAS CSCD 2005年第9期714-720,共7页
The Arabidopsis ICEI (inducer of CBF expression 1) gene was cloned through RT-PCR of Arabidopsis cDNAs and introduced into the lemon (Citrus Limon (L.) Burm. F. cv. Eureka) genome using Agrobacterium-mediated tr... The Arabidopsis ICEI (inducer of CBF expression 1) gene was cloned through RT-PCR of Arabidopsis cDNAs and introduced into the lemon (Citrus Limon (L.) Burm. F. cv. Eureka) genome using Agrobacterium-mediated transformation method. Epicotyl segments from in vitro grown lemon seedlings were co-cultivated with A. tumefaciens strain EHA 105 carrying the binary plasmid pMVICE1, whose T-DNA region contain ICEI gene driven by 35S CaMV promoter. Among 320 epicotyl segments inoculated, 71 explants responded and regenerated 51 elongated shoots. These shoots were subjected to an extra month of kanamycin exposure. In this way, the number of escapes reduced. Thirteen of 31 survived shoots formed roots and 7 were tested positive using PCR technique. Southern blot analyses confirmed PCR results and demonstrated that more than two copies of the ICE1 gene were integrated into the lemon genome. 展开更多
关键词 LEMON ICE1 Agrobacterium-mediated transformation REGENERATION
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Reprogramming of a defense signaling pathway in rough lemon and sweet orange is a critical element of the early response to‘Candidatus Liberibacter asiaticus’ 被引量:9
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作者 Qibin Yu Chunxian Chen +5 位作者 Dongliang Du Ming Huang Jiqiang Yao Fahong Yu Ronald H Brlansky Frederick G.Gmitter Jr 《Horticulture Research》 SCIE 2017年第1期62-76,共15页
Huanglongbing(HLB)in citrus infected by Candidatus Liberibacter asiaticus(CLas)has caused tremendous losses to the citrus industry.No resistant genotypes have been identified in citrus species or close relatives.Among... Huanglongbing(HLB)in citrus infected by Candidatus Liberibacter asiaticus(CLas)has caused tremendous losses to the citrus industry.No resistant genotypes have been identified in citrus species or close relatives.Among citrus varieties,rough lemon(Citrus jambhiri)has been considered tolerant due to its ability to produce a healthy flush of new growth after infection.The difference between tolerance and susceptibility is often defined by the speed and intensity of a plant’s response to a pathogen,especially early defense responses.RNA-seq data were collected from three biological replicates of CLas-and mock-inoculated rough lemon and sweet orange at week 0 and 7 following infection.Functional analysis of the differentially expressed genes(DEGs)indicated that genes involved in the mitogen activated protein kinase(MAPK)signaling pathway were highly upregulated in rough lemon.MAPK induces the transcription of WRKY and other transcription factors which potentially turn on multiple defense-related genes.A Subnetwork Enrichment Analysis further revealed different patterns of regulation of several functional categories,suggesting DEGs with different functions were subjected to reprogramming.In general,the amplitude of the expression of defense-related genes is much greater in rough lemon than in sweet orange.A quantitative disease resistance response may contribute to the durable tolerance level to HLB observed in rough lemon. 展开更多
关键词 CITRUS LEMON ORANGE
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Melissa officinalis and rosmarinic acid in management of memory functions and Alzheimer disease 被引量:2
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作者 Mohaddese Mahboubi 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2019年第2期47-52,共6页
Alzheimer disease(AD) as worldwide progressive neurodegenerative disease is prevalent disease among elderly population. Due to limitation in chemical drugs along with their adverse effects of these treatments, researc... Alzheimer disease(AD) as worldwide progressive neurodegenerative disease is prevalent disease among elderly population. Due to limitation in chemical drugs along with their adverse effects of these treatments, research for finding more effective natural drugs, is one of interesting subjects among the scientists. Melissa officinalis(M. officinalis) has a long history of use in treatment of nervous system diseases. This review article evaluates the potency of M. officinalis in treatment of AD by review of experimental and clinical documents on the efficacy, safety and its mechanisms of action in management of AD. The information is extracted from electronic resources(PubMed, Wiley, Springer and Science Direct), English and Persian scientific books. In spite of different scientific and non-scientific reports on the use of M. officinalis and its main component of rosmarinic acid in neurodegenerative diseases, there is only one clinical trial on the efficacy of M. officinalis ethanol extract in management of AD. Different mechanisms of action for M. officinalis, including inhibitory effects against amyloid beta, reactive oxygen species, and acetylcholine esterase, are involved. Larger clinical trials are recommended to confirm the efficacy and safety of M. officinalis extracts in treatment of AD patients. 展开更多
关键词 LEMON balm MELISSA OFFICINALIS ALZHEIMER ACETYLCHOLINE Rosmarinic acid
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Application of Response Surface Methodology for Optimization of Fluoride Removal Mechanism by Newely Developed Biomaterial 被引量:5
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作者 Ria Bhaumik Naba Kumar Mondal +1 位作者 Soumya Chattoraj Jayanta Kumar Datta 《American Journal of Analytical Chemistry》 2013年第8期404-419,共16页
The adsorption capacities of new biomaterials derived from lemon leaf (Citrus sp.) toward fluoride ions have been explored by varying different physicochemical parameters such as pH, initial concentration, adsorbent d... The adsorption capacities of new biomaterials derived from lemon leaf (Citrus sp.) toward fluoride ions have been explored by varying different physicochemical parameters such as pH, initial concentration, adsorbent dose, contact time, stirring rate and temperature. The entire study was done through batch process. Maximum fluoride adsorption of 96.9% - 98.8% was achieved with an initial concentration of 10 mg/L. Langmuir isotherm model well expressed fluoride ad- sorption onto LLD-1, LLD-2 and LLD-3. According to correlation coefficient, the fluoride adsorption onto these 3 ad- sorbents was correlated well with pseudo-second-order kinetic model. From thermodynamic study, the spontaneous nature and feasibility of the adsorption process with negative enthalpy (&#916H0) value also supported the exothermic nature were shown. The rate of fluoride adsorption was mathematically described as a function of experimental parameters and was modeled through Box-Behnken (Response surface methodology). The results showed that the responses of fluoride adsorption were significantly affected by the quadratic term of pH, initial concentration, contact time and temperature and the statistical analysis was performed by ANOVA which indicated good correlation of experimental parameters. 展开更多
关键词 LEMON Leaf FLUORIDE Adsorption LANGMUIR ISOTHERM Pseudo-Second-Order Kinetic Model THERMODYNAMIC Study Response Surface Methodology
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Dietary bioactives and essential oils of lemon and lime fruits 被引量:2
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作者 Siyu Liu Shiming Li Chi-Tang Ho 《Food Science and Human Wellness》 SCIE 2022年第4期753-764,共12页
Human beings have consumed lemon(Citrus limon)and lime(Citrus aurantifolia or Citrus latiflia)for thousands of years.Among the variety of citrus families,lemon and lime are originated from the hybridization of citron ... Human beings have consumed lemon(Citrus limon)and lime(Citrus aurantifolia or Citrus latiflia)for thousands of years.Among the variety of citrus families,lemon and lime are originated from the hybridization of citron with primitive papeda,hence they are similar from the nutritional and organoleptic standpoints,whereas very different from other citrus species such as orange and mandarin.Except for fresh produce,a signifi cant percentage of lemon and lime are processed and separated as juice,essential oils,pulps and other products.Lemon and lime juice or fruit itself is rich in vitamins,minerals and flavonoids which are rich sources for human nutrition.Consumption of lemon and lime fruit or juice are benefi cial for human health in the scope of urinary citrate increase,oxidative stress relief,improvement in lipid profi les and infl ammation markers,neuroprotective effects among others.These beneficial effects of lemon and lime are not only because of their high vitamin C content but also other bioactive micronutrients such as fl avonoids.Essential oils from lemon and lime have fresh and zesty aroma for perfumery and flavor applications for centuries.Compared with orange or mandarin,the integrated review for lemon and lime dietary bioactive compounds and essential oils is scarce.Therefore,in this review,we introduced the historical cultivation,consumption and process of lemon and lime,discussed the chemical and biological activities of phytochemicals in lemon and lime fruits and juice,and summarized volatile and non-volatile components in lemon and lime oil.This review may provide a comprehensive perspective for entire lemon and lime industry as well as their scientifi c values. 展开更多
关键词 LEMON LIME Essential oils FLAVONOIDS Biological activity
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