The dynamic behaviors of a large-scale ring neural network with a triangular coupling structure are investigated.The characteristic equation of the high-dimensional system using Coate’s flow graph method is calculate...The dynamic behaviors of a large-scale ring neural network with a triangular coupling structure are investigated.The characteristic equation of the high-dimensional system using Coate’s flow graph method is calculated.Time delay is selected as the bifurcation parameter,and sufficient conditions for stability and Hopf bifurcation are derived.It is found that the connection coefficient and time delay play a crucial role in the dynamic behaviors of the model.Furthermore,a phase diagram of multiple equilibrium points with one saddle point and two stable nodes is presented.Finally,the effectiveness of the theory is verified through simulation results.展开更多
It has been argued that the human brain,as an information-processing machine,operates near a phase transition point in a non-equilibrium state,where it violates detailed balance leading to entropy production.Thus,the ...It has been argued that the human brain,as an information-processing machine,operates near a phase transition point in a non-equilibrium state,where it violates detailed balance leading to entropy production.Thus,the assessment of irreversibility in brain networks can provide valuable insights into their non-equilibrium properties.In this study,we utilized an open-source whole-brain functional magnetic resonance imaging(fMRI)dataset from both resting and task states to evaluate the irreversibility of large-scale human brain networks.Our analysis revealed that the brain networks exhibited significant irreversibility,violating detailed balance,and generating entropy.Notably,both physical and cognitive tasks increased the extent of this violation compared to the resting state.Regardless of the state(rest or task),interactions between pairs of brain regions were the primary contributors to this irreversibility.Moreover,we observed that as global synchrony increased within brain networks,so did irreversibility.The first derivative of irreversibility with respect to synchronization peaked near the phase transition point,characterized by the moderate mean synchronization and maximized synchronization entropy of blood oxygenation level-dependent(BOLD)signals.These findings deepen our understanding of the non-equilibrium dynamics of large-scale brain networks,particularly in relation to their phase transition behaviors,and may have potential clinical applications for brain disorders.展开更多
As the first stage of the quantum Internet,quantum key distribution(QKD)networks hold the promise of providing long-term security for diverse users.Most existing QKD networks have been constructed based on independent...As the first stage of the quantum Internet,quantum key distribution(QKD)networks hold the promise of providing long-term security for diverse users.Most existing QKD networks have been constructed based on independent QKD protocols,and they commonly rely on the deployment of single-protocol trusted relay chains for long reach.Driven by the evolution of QKD protocols,large-scale QKD networking is expected to migrate from a single-protocol to a multi-protocol paradigm,during which some useful evolutionary elements for the later stages of the quantum Internet may be incorporated.In this work,we delve into a pivotal technique for large-scale QKD networking,namely,multi-protocol relay chaining.A multi-protocol relay chain is established by connecting a set of trusted/untrusted relays relying on multiple QKD protocols between a pair of QKD nodes.The structures of diverse multi-protocol relay chains are described,based on which the associated model is formulated and the policies are defined for the deployment of multi-protocol relay chains.Furthermore,we propose three multi-protocol relay chaining heuristics.Numerical simulations indicate that the designed heuristics can effectively reduce the number of trusted relays deployed and enhance the average security level versus the commonly used single-protocol trusted relay chaining methods on backbone network topologies.展开更多
The Internet of Things(IoT)ecosystem faces growing security challenges because it is projected to have 76.88 billion devices by 2025 and $1.4 trillion market value by 2027,operating in distributed networks with resour...The Internet of Things(IoT)ecosystem faces growing security challenges because it is projected to have 76.88 billion devices by 2025 and $1.4 trillion market value by 2027,operating in distributed networks with resource limitations and diverse system architectures.The current conventional intrusion detection systems(IDS)face scalability problems and trust-related issues,but blockchain-based solutions face limitations because of their low transaction throughput(Bitcoin:7 TPS(Transactions Per Second),Ethereum:15-30 TPS)and high latency.The research introduces MBID(Multi-Tier Blockchain Intrusion Detection)as a groundbreaking Multi-Tier Blockchain Intrusion Detection System with AI-Enhanced Detection,which solves the problems in huge IoT networks.The MBID system uses a four-tier architecture that includes device,edge,fog,and cloud layers with blockchain implementations and Physics-Informed Neural Networks(PINNs)for edge-based anomaly detection and a dual consensus mechanism that uses Honesty-based Distributed Proof-of-Authority(HDPoA)and Delegated Proof of Stake(DPoS).The system achieves scalability and efficiency through the combination of dynamic sharding and Interplanetary File System(IPFS)integration.Experimental evaluations demonstrate exceptional performance,achieving a detection accuracy of 99.84%,an ultra-low false positive rate of 0.01% with a False Negative Rate of 0.15%,and a near-instantaneous edge detection latency of 0.40 ms.The system demonstrated an aggregate throughput of 214.57 TPS in a 3-shard configuration,providing a clear,evidence-based path for horizontally scaling to support overmillions of devices with exceeding throughput.The proposed architecture represents a significant advancement in blockchain-based security for IoT networks,effectively balancing the trade-offs between scalability,security,and decentralization.展开更多
1.Introduction Climate change mitigation pathways aimed at limiting global anthropogenic carbon dioxide(CO_(2))emissions while striving to constrain the global temperature increase to below 2℃—as outlined by the Int...1.Introduction Climate change mitigation pathways aimed at limiting global anthropogenic carbon dioxide(CO_(2))emissions while striving to constrain the global temperature increase to below 2℃—as outlined by the Intergovernmental Panel on Climate Change(IPCC)—consistently predict the widespread implementation of CO_(2)geological storage on a global scale.展开更多
Emotion and executive control are often conceptualized as two distinct modes of human brain functioning.Little,however,is known about how the dynamic organization of large-scale functional brain networks that support ...Emotion and executive control are often conceptualized as two distinct modes of human brain functioning.Little,however,is known about how the dynamic organization of large-scale functional brain networks that support flexible emotion processing and executive control,especially their interactions.The amygdala and prefrontal systems have long been thought to play crucial roles in these processes.Recent advances in human neuroimaging studies have begun to delineate functional organization principles among the large-scale brain networks underlying emotion,executive control,and their interactions.Here,we propose a dynamic brain network model to account for interactive competition between emotion and executive control by reviewing recent resting-state and task-related neuroimaging studies using network-based approaches.In this model,dynamic interactions among the executive control network,the salience network,the default mode network,and sensorimotor networks enable dynamic processes of emotion and support flexible executive control of multiple processes;neural oscillations across multiple frequency bands and the locus coeruleus−norepinephrine pathway serve as communicational mechanisms underlying dynamic synergy among large-scale functional brain networks.This model has important implications for understanding how the dynamic organization of complex brain systems and networks empowers flexible cognitive and affective functions.展开更多
The titanium alloy strut serves as a key load-bearing component of aircraft landing gear,typically manufactured via forging.The friction condition has important influence on material flow and cavity filling during the...The titanium alloy strut serves as a key load-bearing component of aircraft landing gear,typically manufactured via forging.The friction condition has important influence on material flow and cavity filling during the forging process.Using the previously optimized shape and initial position of preform,the influence of the friction condition(friction factor m=0.1–0.3)on material flow and cavity filling was studied by numerical method with a shear friction model.A novel filling index was defined to reflect material flow into left and right flashes and zoom in on friction-induced results.The results indicate that the workpiece moves rigidly to the right direction,with the displacement decreasing as m increases.When m<0.18,the underfilling defect will occur in the left side of strut forging,while overflow occurs in the right forging die cavity.By combining the filling index and analyses of material flow and filling status,a reasonable friction factor interval of m=0.21–0.24 can be determined.Within this interval,the cavity filling behavior demonstrates robustness,with friction fluctuations exerting minimal influence.展开更多
Guided by molecular networking,nine novel curvularin derivatives(1-9)and 16 known analogs(10-25)were isolated from the hydrothermal vent sediment fungus Penicillium sp.HL-50.Notably,compounds 5-7 represented a hybrid ...Guided by molecular networking,nine novel curvularin derivatives(1-9)and 16 known analogs(10-25)were isolated from the hydrothermal vent sediment fungus Penicillium sp.HL-50.Notably,compounds 5-7 represented a hybrid of curvularin and purine.The structures and absolute configurations of compounds 1-9 were elucidated via nuclear magnetic resonance(NMR)spectroscopy,X-ray diffraction,electronic circular dichroism(ECD)calculations,^(13)C NMR calculation,modified Mosher's method,and chemical derivatization.Investigation of anti-inflammatory activities revealed that compounds 7-9,11,12,14,15,and 18 exhibited significant suppressive effects against lipopolysaccharide(LPS)-induced nitric oxide(NO)production in murine macrophage RAW264.7 cells,with IC_(50)values ranging from 0.44 to 4.40μmol·L^(-1).Furthermore,these bioactive compounds were found to suppress the expression of inflammation-related proteins,including inducible NO synthase(i NOS),cyclooxygenase-2(COX-2),NLR family pyrin domain-containing protein 3(NLRP3),and nuclear factor kappa-B(NF-κB).Additional studies demonstrated that the novel compound 7 possessed potent antiinflammatory activity by inhibiting the transcription of inflammation-related genes,downregulating the expression of inflammation-related proteins,and inhibiting the release of inflammatory cytokines,indicating its potential application in the treatment of inflammatory diseases.展开更多
Based on questionnaire surveys and field interviews conducted with various types of agricultural production organizations across five districts and four counties in Daqing City,this study combines relevant theoretical...Based on questionnaire surveys and field interviews conducted with various types of agricultural production organizations across five districts and four counties in Daqing City,this study combines relevant theoretical frameworks to systematically examine the evolution,performance,and influencing factors of governance mechanisms within these organizations.Using both quantitative and inductive analytical methods,the paper proposes innovative designs and supporting measures for improving governance mechanisms.The findings reveal that,amid large-scale farmland circulation,the governance mechanisms of agricultural production organizations in Daqing City are evolving from traditional to modern structures.However,challenges remain in areas such as decision-making efficiency,benefit distribution,and supervision mechanisms.In response,this study proposes innovative governance designs focusing on decision-making processes,profit-sharing mechanisms,and risk prevention.Corresponding policy recommendations are also provided to support the sustainable development of agricultural modernization in China.展开更多
Formalizing complex processes and phenomena of a real-world problem may require a large number of variables and constraints,resulting in what is termed a large-scale optimization problem.Nowadays,such large-scale opti...Formalizing complex processes and phenomena of a real-world problem may require a large number of variables and constraints,resulting in what is termed a large-scale optimization problem.Nowadays,such large-scale optimization problems are solved using computing machines,leading to an enormous computational time being required,which may delay deriving timely solutions.Decomposition methods,which partition a large-scale optimization problem into lower-dimensional subproblems,represent a key approach to addressing time-efficiency issues.There has been significant progress in both applied mathematics and emerging artificial intelligence approaches on this front.This work aims at providing an overview of the decomposition methods from both the mathematics and computer science points of view.We also remark on the state-of-the-art developments and recent applications of the decomposition methods,and discuss the future research and development perspectives.展开更多
This article focuses on the management of large-scale machinery and equipment in highway construction,with the research objective of identifying issues at the management level and exploring more effective management m...This article focuses on the management of large-scale machinery and equipment in highway construction,with the research objective of identifying issues at the management level and exploring more effective management measures.Through practical observation and logical analysis,this article elaborates on the management connotations of large-scale machinery and equipment in highway construction,affirming its management value from different perspectives.On this basis,it carefully analyzes the problems existing in the management of large-scale machinery and equipment,providing a detailed interpretation of issues such as the weak foundation of the equipment management system and the disconnection between equipment selection and configuration from reality.Combining the manifestations of related problems,this article proposes strategies such as strengthening the institutional foundation of equipment management,selecting and configuring equipment based on actual conditions,aiming to provide references for large-scale machinery and equipment management to relevant enterprises.展开更多
With the large-scale deployment of satellite constellations such as Starlink and the rapid advancement of technologies including artificial intelligence (AI) and non-terrestrial networks (NTNs), the integration of hig...With the large-scale deployment of satellite constellations such as Starlink and the rapid advancement of technologies including artificial intelligence (AI) and non-terrestrial networks (NTNs), the integration of high, medium, and low Earth orbit satellite networks with terrestrial networks has become a critical direction for future communication technologies. The objective is to develop a space-terrestrial integrated 6G network that ensures ubiquitous connectivity and seamless services, facilitating intelligent interconnection and collaborative symbiosis among humans, machines, and objects. This integration has become a central focus of global technological innovation.展开更多
The recent upsurge in metro construction emphasizes the necessity of understanding the mechanical performance of metro shield tunnel subjected to the influence of ground fissures.In this study,a largescale experiment,...The recent upsurge in metro construction emphasizes the necessity of understanding the mechanical performance of metro shield tunnel subjected to the influence of ground fissures.In this study,a largescale experiment,in combination with numerical simulation,was conducted to investigate the influence of ground fissures on a metro shield tunnel.The results indicate that the lining contact pressure at the vault increases in the hanging wall while decreases in the footwall,resulting in a two-dimensional stress state of vertical shear and axial tension-compression,and simultaneous vertical dislocation and axial tilt for the segments around the ground fissure.In addition,the damage to curved bolts includes tensile yield,flexural yield,and shear twist,leading to obvious concrete lining damage,particularly at the vault,arch bottom,and hance,indicating that the joints in these positions are weak areas.The shield tunnel orthogonal to the ground fissure ultimately experiences shear failure,suggesting that the maximum actual dislocation of ground fissure that the structure can withstand is approximately 20 cm,and five segment rings in the hanging wall and six segment rings in the footwall also need to be reinforced.This study could provide a reference for metro design in ground fissure sites.展开更多
Offshore wind power plays a crucial role in energy strategies.The results of traditional small-scale physical models may be unreliable when extrapolated to large field scales.This study addressed this limitation by co...Offshore wind power plays a crucial role in energy strategies.The results of traditional small-scale physical models may be unreliable when extrapolated to large field scales.This study addressed this limitation by conducting large-scale(1:13)experiments to investigate the scour hole pattern and equilibrium scour depth around both slender and large monopiles under irregular waves.The experiments adopted KeuleganeCarpenter number(NKC)values from 1.01 to 8.89 and diffraction parameter(D/L,where D is the diameter of the monopile,and L is the wave length)values from 0.016 to 0.056.The results showed that changes in the maximum scour location and scour hole shape around a slender monopile were associated with NKC,with differences observed between irregular and regular waves.Improving the calculation of NKC enhanced the accuracy of existing scour formulae under irregular waves.The maximum scour locations around a large monopile were consistently found on both sides,regardless of NKC and D/L,but the scour hole topography was influenced by both parameters.Notably,the scour range around a large monopile was at least as large as the monopile diameter.展开更多
In 2022, South China(SC) experienced record-breaking rainfall during its first rainy season, causing severe socioeconomic losses. This study examines the large-scale circulation anomalies responsible for this extreme ...In 2022, South China(SC) experienced record-breaking rainfall during its first rainy season, causing severe socioeconomic losses. This study examines the large-scale circulation anomalies responsible for this extreme event.Analysis reveals that the lower-tropospheric cyclonic anomaly over SC plays a crucial role. This cyclonic anomaly consists of extratropical northeasterly anomalies to the north of SC and tropical southwesterly anomalies to the south. Both components were particularly intense during the 2022 first rainy season, contributing to the heavy rainfall in SC. Moreover,the lower-tropospheric cyclonic anomaly is enhanced by its counterpart in the upper troposphere, which is associated with a wave train propagating from the North Atlantic to East Asia across the mid-high latitudes of the Eurasian continent.Further analysis indicates that the extratropical wave train correlates with sea surface temperature anomalies(SSTAs) in the North Atlantic. Additionally, the SSTAs over the North Indian Ocean also play a role in enhancing the tropical southwesterlies in the lower troposphere. This study highlights the combined influence of tropical and extratropical circulation anomalies, offering a comprehensive understanding of the record-breaking rainfall.展开更多
With the development of big data and social computing,large-scale group decisionmaking(LGDM)is nowmerging with social networks.Using social network analysis(SNA),this study proposes an LGDM consensus model that consid...With the development of big data and social computing,large-scale group decisionmaking(LGDM)is nowmerging with social networks.Using social network analysis(SNA),this study proposes an LGDM consensus model that considers the trust relationship among decisionmakers(DMs).In the process of consensusmeasurement:the social network is constructed according to the social relationship among DMs,and the Louvain method is introduced to classify social networks to form subgroups.In this study,the weights of each decision maker and each subgroup are computed by comprehensive network weights and trust weights.In the process of consensus improvement:A feedback mechanism with four identification and two direction rules is designed to guide the consensus of the improvement process.Based on the trust relationship among DMs,the preferences are modified,and the corresponding social network is updated to accelerate the consensus.Compared with the previous research,the proposedmodel not only allows the subgroups to be reconstructed and updated during the adjustment process,but also improves the accuracy of the adjustment by the feedbackmechanism.Finally,an example analysis is conducted to verify the effectiveness and flexibility of the proposed method.Moreover,compared with previous studies,the superiority of the proposed method in solving the LGDM problem is highlighted.展开更多
This study employs deformation monitoring data acquired during the construction of the Haoji railway large-scale bridge to investigate the displacement behavior of the subgrades,catenary columns,and tracks.Emphasis is...This study employs deformation monitoring data acquired during the construction of the Haoji railway large-scale bridge to investigate the displacement behavior of the subgrades,catenary columns,and tracks.Emphasis is placed on data acquisition and processing methods using total stations and automated monitoring systems.Through a comprehensive analysis of lateral,longitudinal,and vertical displacement data from 26 subgrade monitoring points,catenary columns,and track sections,this research evaluates how construction activities influence railway structures.The results show that displacement variations in the subgrades,catenary columns,and tracks remained within the established alert thresholds,exhibiting stable deformation trends and indicating that any adverse environmental impact was effectively contained.Furthermore,this paper proposes an early warning mechanism based on an automated monitoring system,which can promptly detect abnormal deformations and initiate emergency response procedures,thereby ensuring the safe operation of the railway.The integration of big data analysis and deformation prediction models offers a practical foundation for future safety management in railway construction.展开更多
The research on optimization methods for constellation launch deployment strategies focused on the consideration of mission interval time constraints at the launch site.Firstly,a dynamic modeling of the constellation ...The research on optimization methods for constellation launch deployment strategies focused on the consideration of mission interval time constraints at the launch site.Firstly,a dynamic modeling of the constellation deployment process was established,and the relationship between the deployment window and the phase difference of the orbit insertion point,as well as the cost of phase adjustment after orbit insertion,was derived.Then,the combination of the constellation deployment position sequence was treated as a parameter,together with the sequence of satellite deployment intervals,as optimization variables,simplifying a highdimensional search problem within a wide range of dates to a finite-dimensional integer programming problem.An improved genetic algorithm with local search on deployment dates was introduced to optimize the launch deployment strategy.With the new description of the optimization variables,the total number of elements in the solution space was reduced by N orders of magnitude.Numerical simulation confirms that the proposed optimization method accelerates the convergence speed from hours to minutes.展开更多
The existing deep-sea sediment plume tests are mostly under small-scale static water and rarely under large-scale flowing water conditions.In this study,large-scale tank experiments of flowing water were designed and ...The existing deep-sea sediment plume tests are mostly under small-scale static water and rarely under large-scale flowing water conditions.In this study,large-scale tank experiments of flowing water were designed and conducted to investigate the morphological characteristics and concentration evolution of the sediment plumes under different discharge rates(Q)and initial sediment concentrations(c).Viscosity tests,resuspension tests and free settling tests of the sediment solution with different c values were performed to reveal the settling mechanism of the plume diffusion process.The results show that the plume diffusion morphology variation in flowing water has four stages and the plume concentration evolution has three stages.The larger the Q,the smaller the initial incidence angle at the discharge outlet,the larger the diffusion range,the poorer the stability and the more complicated the diffusion morphology.The larger the c,the larger the settling velocity,the faster the formation of high-concentration accumulation zone,the better the stability and the clearer the diffusion boundary.The research results could provide experimental data for assessing the impact of deep-sea mining on the ocean environment.展开更多
This study examined the development of technician teams on large-scale instrument platforms in universities,using the State Key Laboratory of Natural and Biomimetic Drugs in the Peking University School of Pharmaceuti...This study examined the development of technician teams on large-scale instrument platforms in universities,using the State Key Laboratory of Natural and Biomimetic Drugs in the Peking University School of Pharmaceutical Sciences as a case study.Data were collected through questionnaire surveys and interviews conducted in 2017,followed by a questionnaire survey in 2023,offering both subjective and objective insights.The evolution of the platform’s technician team over the past 5 years was analyzed,highlighting key experiences and identifying ongoing challenges.Recommendations to enhance technician team development include recruiting skilled faculty,clearly defining job responsibilities,and refining the assessment and incentive systems.展开更多
基金Supported by Natural Science Foundation of Shandong Province of China(Grant Nos.ZR2020MF080 and ZR2020MF065).
文摘The dynamic behaviors of a large-scale ring neural network with a triangular coupling structure are investigated.The characteristic equation of the high-dimensional system using Coate’s flow graph method is calculated.Time delay is selected as the bifurcation parameter,and sufficient conditions for stability and Hopf bifurcation are derived.It is found that the connection coefficient and time delay play a crucial role in the dynamic behaviors of the model.Furthermore,a phase diagram of multiple equilibrium points with one saddle point and two stable nodes is presented.Finally,the effectiveness of the theory is verified through simulation results.
基金supported by the Fundamental Research Funds for the Central Universities(Grant Nos.lzujbky-2021-62 and lzujbky-2024-jdzx06)the National Natural Science Foundation of China(Grant No.12247101)+1 种基金the Natural Science Foundation of Gansu Province,China(Grant Nos.22JR5RA389 and 23JRRA1740)the‘111 Center’Fund(Grant No.B20063).
文摘It has been argued that the human brain,as an information-processing machine,operates near a phase transition point in a non-equilibrium state,where it violates detailed balance leading to entropy production.Thus,the assessment of irreversibility in brain networks can provide valuable insights into their non-equilibrium properties.In this study,we utilized an open-source whole-brain functional magnetic resonance imaging(fMRI)dataset from both resting and task states to evaluate the irreversibility of large-scale human brain networks.Our analysis revealed that the brain networks exhibited significant irreversibility,violating detailed balance,and generating entropy.Notably,both physical and cognitive tasks increased the extent of this violation compared to the resting state.Regardless of the state(rest or task),interactions between pairs of brain regions were the primary contributors to this irreversibility.Moreover,we observed that as global synchrony increased within brain networks,so did irreversibility.The first derivative of irreversibility with respect to synchronization peaked near the phase transition point,characterized by the moderate mean synchronization and maximized synchronization entropy of blood oxygenation level-dependent(BOLD)signals.These findings deepen our understanding of the non-equilibrium dynamics of large-scale brain networks,particularly in relation to their phase transition behaviors,and may have potential clinical applications for brain disorders.
基金supported in part by the National Natural Science Foundation of China(Grant Nos.62201276,62350001,U22B2026,and 62471248)Innovation Program for Quantum Science and Technology(Grant No.2021ZD0300701)+1 种基金the Key R&D Program(Industry Foresight and Key Core Technologies)of Jiangsu Province(Grant No.BE2022071)Natural Science Research of Jiangsu Higher Education Institutions of China(Grant No.22KJB510007)。
文摘As the first stage of the quantum Internet,quantum key distribution(QKD)networks hold the promise of providing long-term security for diverse users.Most existing QKD networks have been constructed based on independent QKD protocols,and they commonly rely on the deployment of single-protocol trusted relay chains for long reach.Driven by the evolution of QKD protocols,large-scale QKD networking is expected to migrate from a single-protocol to a multi-protocol paradigm,during which some useful evolutionary elements for the later stages of the quantum Internet may be incorporated.In this work,we delve into a pivotal technique for large-scale QKD networking,namely,multi-protocol relay chaining.A multi-protocol relay chain is established by connecting a set of trusted/untrusted relays relying on multiple QKD protocols between a pair of QKD nodes.The structures of diverse multi-protocol relay chains are described,based on which the associated model is formulated and the policies are defined for the deployment of multi-protocol relay chains.Furthermore,we propose three multi-protocol relay chaining heuristics.Numerical simulations indicate that the designed heuristics can effectively reduce the number of trusted relays deployed and enhance the average security level versus the commonly used single-protocol trusted relay chaining methods on backbone network topologies.
基金supported in part by Multimedia University under the Research Fellow Grant MMUI/250008in part by Telekom Research&Development Sdn Bhd underGrantRDTC/241149Princess Nourah bint Abdulrahman University Researchers Supporting Project number(PNURSP2025R140),Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia.
文摘The Internet of Things(IoT)ecosystem faces growing security challenges because it is projected to have 76.88 billion devices by 2025 and $1.4 trillion market value by 2027,operating in distributed networks with resource limitations and diverse system architectures.The current conventional intrusion detection systems(IDS)face scalability problems and trust-related issues,but blockchain-based solutions face limitations because of their low transaction throughput(Bitcoin:7 TPS(Transactions Per Second),Ethereum:15-30 TPS)and high latency.The research introduces MBID(Multi-Tier Blockchain Intrusion Detection)as a groundbreaking Multi-Tier Blockchain Intrusion Detection System with AI-Enhanced Detection,which solves the problems in huge IoT networks.The MBID system uses a four-tier architecture that includes device,edge,fog,and cloud layers with blockchain implementations and Physics-Informed Neural Networks(PINNs)for edge-based anomaly detection and a dual consensus mechanism that uses Honesty-based Distributed Proof-of-Authority(HDPoA)and Delegated Proof of Stake(DPoS).The system achieves scalability and efficiency through the combination of dynamic sharding and Interplanetary File System(IPFS)integration.Experimental evaluations demonstrate exceptional performance,achieving a detection accuracy of 99.84%,an ultra-low false positive rate of 0.01% with a False Negative Rate of 0.15%,and a near-instantaneous edge detection latency of 0.40 ms.The system demonstrated an aggregate throughput of 214.57 TPS in a 3-shard configuration,providing a clear,evidence-based path for horizontally scaling to support overmillions of devices with exceeding throughput.The proposed architecture represents a significant advancement in blockchain-based security for IoT networks,effectively balancing the trade-offs between scalability,security,and decentralization.
基金supported by the National Key Research and Development Program of China(2022YFE0206700)。
文摘1.Introduction Climate change mitigation pathways aimed at limiting global anthropogenic carbon dioxide(CO_(2))emissions while striving to constrain the global temperature increase to below 2℃—as outlined by the Intergovernmental Panel on Climate Change(IPCC)—consistently predict the widespread implementation of CO_(2)geological storage on a global scale.
基金supported by the National Natural Science Foundation of China(31920103009,32371104,and 32130045)the Major Project of National Social Science Foundation(20&ZD153)the Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions(2023SHIBS0003).
文摘Emotion and executive control are often conceptualized as two distinct modes of human brain functioning.Little,however,is known about how the dynamic organization of large-scale functional brain networks that support flexible emotion processing and executive control,especially their interactions.The amygdala and prefrontal systems have long been thought to play crucial roles in these processes.Recent advances in human neuroimaging studies have begun to delineate functional organization principles among the large-scale brain networks underlying emotion,executive control,and their interactions.Here,we propose a dynamic brain network model to account for interactive competition between emotion and executive control by reviewing recent resting-state and task-related neuroimaging studies using network-based approaches.In this model,dynamic interactions among the executive control network,the salience network,the default mode network,and sensorimotor networks enable dynamic processes of emotion and support flexible executive control of multiple processes;neural oscillations across multiple frequency bands and the locus coeruleus−norepinephrine pathway serve as communicational mechanisms underlying dynamic synergy among large-scale functional brain networks.This model has important implications for understanding how the dynamic organization of complex brain systems and networks empowers flexible cognitive and affective functions.
基金National Natural Science Foundation of China(52375378)National Key Laboratory of Metal Forming Technology and Heavy Equipment(S2308100.W12)Huxiang High-Level Talent Gathering Project of Hunan Province(2021RC5001)。
文摘The titanium alloy strut serves as a key load-bearing component of aircraft landing gear,typically manufactured via forging.The friction condition has important influence on material flow and cavity filling during the forging process.Using the previously optimized shape and initial position of preform,the influence of the friction condition(friction factor m=0.1–0.3)on material flow and cavity filling was studied by numerical method with a shear friction model.A novel filling index was defined to reflect material flow into left and right flashes and zoom in on friction-induced results.The results indicate that the workpiece moves rigidly to the right direction,with the displacement decreasing as m increases.When m<0.18,the underfilling defect will occur in the left side of strut forging,while overflow occurs in the right forging die cavity.By combining the filling index and analyses of material flow and filling status,a reasonable friction factor interval of m=0.21–0.24 can be determined.Within this interval,the cavity filling behavior demonstrates robustness,with friction fluctuations exerting minimal influence.
基金funded by the National Key Research and Development Program of China(No.2022YFC2804101)the Guangdong Provincial Key R&D Program(No.2023B1111050011)+2 种基金the Guangdong Basic and Applied Basic Research Foundation(No.2023A1515010432)the Guangzhou Basic and Applied Basic Research Foundation(No.202201010305)the High-Level Talents Special Program of Zhejiang(No.2022R52036)。
文摘Guided by molecular networking,nine novel curvularin derivatives(1-9)and 16 known analogs(10-25)were isolated from the hydrothermal vent sediment fungus Penicillium sp.HL-50.Notably,compounds 5-7 represented a hybrid of curvularin and purine.The structures and absolute configurations of compounds 1-9 were elucidated via nuclear magnetic resonance(NMR)spectroscopy,X-ray diffraction,electronic circular dichroism(ECD)calculations,^(13)C NMR calculation,modified Mosher's method,and chemical derivatization.Investigation of anti-inflammatory activities revealed that compounds 7-9,11,12,14,15,and 18 exhibited significant suppressive effects against lipopolysaccharide(LPS)-induced nitric oxide(NO)production in murine macrophage RAW264.7 cells,with IC_(50)values ranging from 0.44 to 4.40μmol·L^(-1).Furthermore,these bioactive compounds were found to suppress the expression of inflammation-related proteins,including inducible NO synthase(i NOS),cyclooxygenase-2(COX-2),NLR family pyrin domain-containing protein 3(NLRP3),and nuclear factor kappa-B(NF-κB).Additional studies demonstrated that the novel compound 7 possessed potent antiinflammatory activity by inhibiting the transcription of inflammation-related genes,downregulating the expression of inflammation-related proteins,and inhibiting the release of inflammatory cytokines,indicating its potential application in the treatment of inflammatory diseases.
基金Supported by Daqing City Philosophy and Social Sciences Planning Research Project(DSGB 2025011)the Heilongjiang Province Education Science Planning Key Project(GJB1320229).
文摘Based on questionnaire surveys and field interviews conducted with various types of agricultural production organizations across five districts and four counties in Daqing City,this study combines relevant theoretical frameworks to systematically examine the evolution,performance,and influencing factors of governance mechanisms within these organizations.Using both quantitative and inductive analytical methods,the paper proposes innovative designs and supporting measures for improving governance mechanisms.The findings reveal that,amid large-scale farmland circulation,the governance mechanisms of agricultural production organizations in Daqing City are evolving from traditional to modern structures.However,challenges remain in areas such as decision-making efficiency,benefit distribution,and supervision mechanisms.In response,this study proposes innovative governance designs focusing on decision-making processes,profit-sharing mechanisms,and risk prevention.Corresponding policy recommendations are also provided to support the sustainable development of agricultural modernization in China.
基金The Australian Research Council(DP200101197,DP230101107).
文摘Formalizing complex processes and phenomena of a real-world problem may require a large number of variables and constraints,resulting in what is termed a large-scale optimization problem.Nowadays,such large-scale optimization problems are solved using computing machines,leading to an enormous computational time being required,which may delay deriving timely solutions.Decomposition methods,which partition a large-scale optimization problem into lower-dimensional subproblems,represent a key approach to addressing time-efficiency issues.There has been significant progress in both applied mathematics and emerging artificial intelligence approaches on this front.This work aims at providing an overview of the decomposition methods from both the mathematics and computer science points of view.We also remark on the state-of-the-art developments and recent applications of the decomposition methods,and discuss the future research and development perspectives.
文摘This article focuses on the management of large-scale machinery and equipment in highway construction,with the research objective of identifying issues at the management level and exploring more effective management measures.Through practical observation and logical analysis,this article elaborates on the management connotations of large-scale machinery and equipment in highway construction,affirming its management value from different perspectives.On this basis,it carefully analyzes the problems existing in the management of large-scale machinery and equipment,providing a detailed interpretation of issues such as the weak foundation of the equipment management system and the disconnection between equipment selection and configuration from reality.Combining the manifestations of related problems,this article proposes strategies such as strengthening the institutional foundation of equipment management,selecting and configuring equipment based on actual conditions,aiming to provide references for large-scale machinery and equipment management to relevant enterprises.
文摘With the large-scale deployment of satellite constellations such as Starlink and the rapid advancement of technologies including artificial intelligence (AI) and non-terrestrial networks (NTNs), the integration of high, medium, and low Earth orbit satellite networks with terrestrial networks has become a critical direction for future communication technologies. The objective is to develop a space-terrestrial integrated 6G network that ensures ubiquitous connectivity and seamless services, facilitating intelligent interconnection and collaborative symbiosis among humans, machines, and objects. This integration has become a central focus of global technological innovation.
基金supported by the National Key Research&Development Program of China(Grant No.2023YFC3008404)the Key Laboratory of Earth Fissures Geological Disaster,Ministry of Natural Resources,China(Grant Nos.EFGD20240609 and EFGD20240610).
文摘The recent upsurge in metro construction emphasizes the necessity of understanding the mechanical performance of metro shield tunnel subjected to the influence of ground fissures.In this study,a largescale experiment,in combination with numerical simulation,was conducted to investigate the influence of ground fissures on a metro shield tunnel.The results indicate that the lining contact pressure at the vault increases in the hanging wall while decreases in the footwall,resulting in a two-dimensional stress state of vertical shear and axial tension-compression,and simultaneous vertical dislocation and axial tilt for the segments around the ground fissure.In addition,the damage to curved bolts includes tensile yield,flexural yield,and shear twist,leading to obvious concrete lining damage,particularly at the vault,arch bottom,and hance,indicating that the joints in these positions are weak areas.The shield tunnel orthogonal to the ground fissure ultimately experiences shear failure,suggesting that the maximum actual dislocation of ground fissure that the structure can withstand is approximately 20 cm,and five segment rings in the hanging wall and six segment rings in the footwall also need to be reinforced.This study could provide a reference for metro design in ground fissure sites.
基金supported by the National Nature Science Foundation of China National Outstanding Youth Science Fund Project(Grant No.52122109)the National Natural Science Foundation of China(Grants No.51861165102 and 52039005).
文摘Offshore wind power plays a crucial role in energy strategies.The results of traditional small-scale physical models may be unreliable when extrapolated to large field scales.This study addressed this limitation by conducting large-scale(1:13)experiments to investigate the scour hole pattern and equilibrium scour depth around both slender and large monopiles under irregular waves.The experiments adopted KeuleganeCarpenter number(NKC)values from 1.01 to 8.89 and diffraction parameter(D/L,where D is the diameter of the monopile,and L is the wave length)values from 0.016 to 0.056.The results showed that changes in the maximum scour location and scour hole shape around a slender monopile were associated with NKC,with differences observed between irregular and regular waves.Improving the calculation of NKC enhanced the accuracy of existing scour formulae under irregular waves.The maximum scour locations around a large monopile were consistently found on both sides,regardless of NKC and D/L,but the scour hole topography was influenced by both parameters.Notably,the scour range around a large monopile was at least as large as the monopile diameter.
基金Guangdong Major Project of Basic and Applied Basic Research (2020B0301030004)National Natural Science Foundation of China (42275041)Hainan Province Science and Technology Special Fund (SOLZSKY2025006)。
文摘In 2022, South China(SC) experienced record-breaking rainfall during its first rainy season, causing severe socioeconomic losses. This study examines the large-scale circulation anomalies responsible for this extreme event.Analysis reveals that the lower-tropospheric cyclonic anomaly over SC plays a crucial role. This cyclonic anomaly consists of extratropical northeasterly anomalies to the north of SC and tropical southwesterly anomalies to the south. Both components were particularly intense during the 2022 first rainy season, contributing to the heavy rainfall in SC. Moreover,the lower-tropospheric cyclonic anomaly is enhanced by its counterpart in the upper troposphere, which is associated with a wave train propagating from the North Atlantic to East Asia across the mid-high latitudes of the Eurasian continent.Further analysis indicates that the extratropical wave train correlates with sea surface temperature anomalies(SSTAs) in the North Atlantic. Additionally, the SSTAs over the North Indian Ocean also play a role in enhancing the tropical southwesterlies in the lower troposphere. This study highlights the combined influence of tropical and extratropical circulation anomalies, offering a comprehensive understanding of the record-breaking rainfall.
基金The work was supported by Humanities and Social Sciences Fund of the Ministry of Education(No.22YJA630119)the National Natural Science Foundation of China(No.71971051)Natural Science Foundation of Hebei Province(No.G2021501004).
文摘With the development of big data and social computing,large-scale group decisionmaking(LGDM)is nowmerging with social networks.Using social network analysis(SNA),this study proposes an LGDM consensus model that considers the trust relationship among decisionmakers(DMs).In the process of consensusmeasurement:the social network is constructed according to the social relationship among DMs,and the Louvain method is introduced to classify social networks to form subgroups.In this study,the weights of each decision maker and each subgroup are computed by comprehensive network weights and trust weights.In the process of consensus improvement:A feedback mechanism with four identification and two direction rules is designed to guide the consensus of the improvement process.Based on the trust relationship among DMs,the preferences are modified,and the corresponding social network is updated to accelerate the consensus.Compared with the previous research,the proposedmodel not only allows the subgroups to be reconstructed and updated during the adjustment process,but also improves the accuracy of the adjustment by the feedbackmechanism.Finally,an example analysis is conducted to verify the effectiveness and flexibility of the proposed method.Moreover,compared with previous studies,the superiority of the proposed method in solving the LGDM problem is highlighted.
文摘This study employs deformation monitoring data acquired during the construction of the Haoji railway large-scale bridge to investigate the displacement behavior of the subgrades,catenary columns,and tracks.Emphasis is placed on data acquisition and processing methods using total stations and automated monitoring systems.Through a comprehensive analysis of lateral,longitudinal,and vertical displacement data from 26 subgrade monitoring points,catenary columns,and track sections,this research evaluates how construction activities influence railway structures.The results show that displacement variations in the subgrades,catenary columns,and tracks remained within the established alert thresholds,exhibiting stable deformation trends and indicating that any adverse environmental impact was effectively contained.Furthermore,this paper proposes an early warning mechanism based on an automated monitoring system,which can promptly detect abnormal deformations and initiate emergency response procedures,thereby ensuring the safe operation of the railway.The integration of big data analysis and deformation prediction models offers a practical foundation for future safety management in railway construction.
文摘The research on optimization methods for constellation launch deployment strategies focused on the consideration of mission interval time constraints at the launch site.Firstly,a dynamic modeling of the constellation deployment process was established,and the relationship between the deployment window and the phase difference of the orbit insertion point,as well as the cost of phase adjustment after orbit insertion,was derived.Then,the combination of the constellation deployment position sequence was treated as a parameter,together with the sequence of satellite deployment intervals,as optimization variables,simplifying a highdimensional search problem within a wide range of dates to a finite-dimensional integer programming problem.An improved genetic algorithm with local search on deployment dates was introduced to optimize the launch deployment strategy.With the new description of the optimization variables,the total number of elements in the solution space was reduced by N orders of magnitude.Numerical simulation confirms that the proposed optimization method accelerates the convergence speed from hours to minutes.
基金supported by the Major Project of Hunan Natural Science Foundation,China(No.2021JC0010)the National Natural Science Foundation of China(No.51274251)。
文摘The existing deep-sea sediment plume tests are mostly under small-scale static water and rarely under large-scale flowing water conditions.In this study,large-scale tank experiments of flowing water were designed and conducted to investigate the morphological characteristics and concentration evolution of the sediment plumes under different discharge rates(Q)and initial sediment concentrations(c).Viscosity tests,resuspension tests and free settling tests of the sediment solution with different c values were performed to reveal the settling mechanism of the plume diffusion process.The results show that the plume diffusion morphology variation in flowing water has four stages and the plume concentration evolution has three stages.The larger the Q,the smaller the initial incidence angle at the discharge outlet,the larger the diffusion range,the poorer the stability and the more complicated the diffusion morphology.The larger the c,the larger the settling velocity,the faster the formation of high-concentration accumulation zone,the better the stability and the clearer the diffusion boundary.The research results could provide experimental data for assessing the impact of deep-sea mining on the ocean environment.
文摘This study examined the development of technician teams on large-scale instrument platforms in universities,using the State Key Laboratory of Natural and Biomimetic Drugs in the Peking University School of Pharmaceutical Sciences as a case study.Data were collected through questionnaire surveys and interviews conducted in 2017,followed by a questionnaire survey in 2023,offering both subjective and objective insights.The evolution of the platform’s technician team over the past 5 years was analyzed,highlighting key experiences and identifying ongoing challenges.Recommendations to enhance technician team development include recruiting skilled faculty,clearly defining job responsibilities,and refining the assessment and incentive systems.
