Hydrogel fibers have gained considerable attention,but their large-scale production and industrial application are currently constrained.The key lies in precise diameter control and industrial manufacturing with a str...Hydrogel fibers have gained considerable attention,but their large-scale production and industrial application are currently constrained.The key lies in precise diameter control and industrial manufacturing with a straightforward,energy-saving,and efficient strategy.Herein,we introduce a hydrodynamic drafting spinning platform inspired by water vortices.It employs the rotation of a nonsolvent to generate vortices and further facilitate the efficient drafting of hydrogel fibers.Through sup-porting equipment,we have achieved impressive results,including scalable production capabilities(1 h,single channel output of 2×10^(3) m of fibers)and extensive adaptability.Subsequently,by simply regulating the velocity difference between fiber extrusion and fluid vortex,hydrogel fibers can be drafted to any diameter from about 1 mm to 5×10^(-2) mm(for chi-tosan system).Notably,this platform endows hydrogel fibers to carry functional hydrophilic or hydrophobic drugs.Equally significant,these delicate hydrogel fibers seamlessly integrate with subsequent manufacturing technologies.This allows the production of various end products,such as fiber bundles,yarns,fabrics,and nonwovens.Furthermore,the immense potential in biomedical applications has been demonstrated after obtaining hydrogel fiber-based nonwoven as wound dress-ings.In summary,the hydrodynamic drafting spinning platform offers an effective solution for the large-scale production of diameter-controllable,multifunctional hydrogel fibers.展开更多
基金supported by the National Natural Science Foundation of China(NSFC)(No.81770091,No.51908246)the Clinical Research Plan of Shanghai Hospital Development Center(multi-center clinical research project for major diseases)(No.SHDC-2020CR1021B)+8 种基金the scientific and technological innovation action plan of Science and Technology Commission of Shanghai Municipality(No.20DZ2253700)the National Natural Science Foundation of China(NSFC)(No.82000099)the Science and Technology Commission of Shanghai Municipality(No.20YF1440900,21YF1438500)the Clinical Research Foundation of Shanghai Pulmonary Hospital(No.FKLY20007)Shanghai Pulmonary Hospital Innovation Team(No.FKCX1906,FKXY1902)Shanghai Pulmonary Hospital Grant(No.FKCY1903)Ningbo Top Medical and Health Research Program(No.2022030208)Clinical Research Foundation of Shanghai Pulmonary Hospital(No.SKPY2021005)Science and Technology Commission of Shanghai Municipality(No.21S31905200).
文摘Hydrogel fibers have gained considerable attention,but their large-scale production and industrial application are currently constrained.The key lies in precise diameter control and industrial manufacturing with a straightforward,energy-saving,and efficient strategy.Herein,we introduce a hydrodynamic drafting spinning platform inspired by water vortices.It employs the rotation of a nonsolvent to generate vortices and further facilitate the efficient drafting of hydrogel fibers.Through sup-porting equipment,we have achieved impressive results,including scalable production capabilities(1 h,single channel output of 2×10^(3) m of fibers)and extensive adaptability.Subsequently,by simply regulating the velocity difference between fiber extrusion and fluid vortex,hydrogel fibers can be drafted to any diameter from about 1 mm to 5×10^(-2) mm(for chi-tosan system).Notably,this platform endows hydrogel fibers to carry functional hydrophilic or hydrophobic drugs.Equally significant,these delicate hydrogel fibers seamlessly integrate with subsequent manufacturing technologies.This allows the production of various end products,such as fiber bundles,yarns,fabrics,and nonwovens.Furthermore,the immense potential in biomedical applications has been demonstrated after obtaining hydrogel fiber-based nonwoven as wound dress-ings.In summary,the hydrodynamic drafting spinning platform offers an effective solution for the large-scale production of diameter-controllable,multifunctional hydrogel fibers.
