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Large-stroke snap-through instability in the axial direction of a bi-stable structure with high slenderness
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作者 Huan Zhou Qian Sun +4 位作者 Haibin Xia Yiwei Xiong Youchao Yuan Yin Huang Jianghong Yuan 《Theoretical & Applied Mechanics Letters》 2025年第1期43-48,共6页
Mechanical snap-through instability of bi-stable structures may find many practical applications such as state switching and energy transforming.Although there exist diverse bi-stable structures capable of snap-throug... Mechanical snap-through instability of bi-stable structures may find many practical applications such as state switching and energy transforming.Although there exist diverse bi-stable structures capable of snap-through instability,it is still difficult for a structure with high slenderness to undergo the axial snap-through instability with a large stroke.Here,an elastic structure with high slenderness is simply constructed by a finite number of identical,conventional bi-stable units with relatively low slenderness in series connection.For realizing the axial snap-through instability with a large stroke,common scissors mechanisms are further introduced as rigid constraints to guarantee the synchronous snap-through instability of these bi-stable units.The global feature of the large-stroke snap-through instability realized here is robust and even insusceptible to the local out-of-synchronization of individual units.The present design provides a simple and feasible way to achieve the large-stroke snap-through instability of slender structures,which is expected to be particularly useful for state switching and energy transforming in narrow spaces. 展开更多
关键词 Synchronous instability Snap-through instability Bi-stability large stroke High slenderness
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Design method for out-of-plane motion rejecting structure in 2-DoF large stroke actuators
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作者 Wei Bian Xiaoguang Zhao +4 位作者 Wenshuai Lu Yijun Yang Junjie Zhang Rui You Fei Xing 《Microsystems & Nanoengineering》 2025年第4期191-207,共17页
This paper addresses a critical challenge in the design of MEMS actuators:the rejection of out-of-plane motion,specifically along the Z-axis,which can severely impact the precision and performance of these micro-actua... This paper addresses a critical challenge in the design of MEMS actuators:the rejection of out-of-plane motion,specifically along the Z-axis,which can severely impact the precision and performance of these micro-actuation systems.In many MEMS applications,unwanted out-of-plane displacement can lead to reduced accuracy in tasks such as optical steering,micro-manipulation,and scanning applications.In response to these limitations,this paper proposes a novel design technique that effectively rejects Z-axis motion by transforming the motion of the micro stage along the Z-axis into equivalent displacements between pairs of points on cantilevers.These point pairs are founded exhibiting variable common-mode and differential-mode motion characteristics,depending on whether the stage is undergoing in-plane(X/Y)or out-of-plane(Z)displacements.By connecting these point pairs with rods,differential motion between the points in the pairs is suppressed,reducing unwanted out-of-plane motion significantly.We provide a detailed analysis of this design methodology and present a practical application in the form of an electromagnetic large displacement MEMS actuator.This actuator undergoes a complete design-simulationmanufacturing-testing cycle,where the effectiveness of the Z-axis motion rejection structure is systematically evaluated,and compared against traditional designs.Experimental results reveal a significant improvement in performance,with static and dynamic travel ranges reaching±60μm and±400μm,respectively.Moreover,the Z-axis stiffness was enhanced by 68.5%,which is more than five times the improvement observed in the X/Y axes’stiffness.These results highlight the potential of the proposed method to provide a robust solution for out-of-plane motion suppression in MEMS actuators,offering improved performance without compromising other critical parameters such as displacement and actuation speed. 展开更多
关键词 z axis motion rejection differential mode motion optical steeringmicro manipulationand plane motion large stroke actuators common mode motion mems actuators design technique
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The characteristics of hybrid transducer type linear ultrasonic motor with large thrust and large stroke 被引量:1
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作者 LI Chaodong JIN Long ZHAO Chunsheng (Institute of Vibration Engineering Research, NUAA Nanjing 210016) 《Chinese Journal of Acoustics》 1999年第3期266-271,共6页
This hybrid transducer type linear ultrasonic motor is a new troe of the lineax ultrasonic motor proposed by the authors. This paper describes its basic structure and operation principle, provides its mechedsm of the ... This hybrid transducer type linear ultrasonic motor is a new troe of the lineax ultrasonic motor proposed by the authors. This paper describes its basic structure and operation principle, provides its mechedsm of the large thrust and large seif lock force when power is cut off. The measured characteristics of the prototype motor are shown, its mtalmum thrust is 11 N and mtalmum output power is 1.4 W, the backward and forward motion performances are roughly coincident 展开更多
关键词 TYPE The characteristics of hybrid transducer type linear ultrasonic motor with large thrust and large stroke
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Oscillating-grid turbulence at large strokes: Revisiting the equation of Hopfinger and Toly
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作者 wan hanna melini wan mohtar 《Journal of Hydrodynamics》 SCIE EI CSCD 2016年第3期473-481,共9页
A quasi-isotropic, quasi-homogeneous turbulence generated by an oscillating-grid, spatially decays according to power law of u ∝ Z-nM , where u is the root mean square (rms) horizontal velocity, Z is the vertical d... A quasi-isotropic, quasi-homogeneous turbulence generated by an oscillating-grid, spatially decays according to power law of u ∝ Z-nM , where u is the root mean square (rms) horizontal velocity, Z is the vertical distance from the grid and nu = 1. However, the findings of Nokes and Yi indicate that as the stroke of oscillation increases, the power law n u= 1 and does not follow the established decay law equation of Hopfinger. This paper investigates the characteristics of the turbulence that are generated using larger strokes S/M = 1.6 and 2 and compares with that obtained using a S/M = 0.8, which is the stroke used when the equation was developed. Measurements of the grid-generated turbulence in a water tank were taken using particle image velocimetry (PIV). The results showed that the homogeneity occurred at distance beyond 2.5 mesh spacings away from the grid midplane, independent of the stroke and the frequency of oscillation. Within this region, the turbulent kinetic energy distribution was quasi-homogeneous, and the secondary mean flow is negligible. The statistical characteristics of the measured turbulence confirmed that although nu decreases as stroke increases, the grid-turbulence generated at S/M = 1.6 and 2 obeys the universal decay law. 展开更多
关键词 oscillating-grid turbulence large strokes decay power law
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Mechanical thrombectomy and postoperative complications after acute ischemic stroke with large vessel occlusion
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作者 WANG Yi-tian AI Xiang-bai +2 位作者 HUANG Xiao-gan FU Chuan-yi ZHAO Jian-nong 《Journal of Hainan Medical University》 CAS 2023年第24期52-57,共6页
Acute ischemic stroke is one of the common discases in Chinese,among which acute ischemic stroke with large vessel occlusion(AIS-LVO)has thc most serious complications and has the risk of death.Studies have shown that... Acute ischemic stroke is one of the common discases in Chinese,among which acute ischemic stroke with large vessel occlusion(AIS-LVO)has thc most serious complications and has the risk of death.Studies have shown that reperfusion is a first-line treatment for the effective rescue of ischemic brain tissue,usually mainly by mechanical|hrombectomy(MT),supplemented by intravenous thrombolysis.However,there are still complications after large blood vessel occlusion and MT.such as blecding and infection at the puncture point,vasospasm,vascular dissection,subarachnoid hemorrhage,hcmonhagic transfomation,reembolization,and massive cerebral infarction,ctc.The high risk factors and corresponding measures of complications after MT by revicwing the rescarch analysis. 展开更多
关键词 Acute ischemic stroke with large vessel occlusion Mechanical thrombectomy COMPLICATIONS
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Analysis on Endovascular Therapy for Acute Ischemic Stroke with Large Vessel Occlusion and Large-Scaled Core Infarct Volume in the Time Window
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作者 Gang Yang Shaojun Yang Yaojie Cai 《World Journal of Neuroscience》 CAS 2022年第4期181-186,共6页
Patients who received endovascular therapy (EVT) for acute ischemic stroke with large vessel occlusion (AIS-LVO) and large-scaled core infarct volume in the time window were analyzed. Literature data were reviewed. Re... Patients who received endovascular therapy (EVT) for acute ischemic stroke with large vessel occlusion (AIS-LVO) and large-scaled core infarct volume in the time window were analyzed. Literature data were reviewed. Results showed that although EVT is the first choice to AIS-LVO, patients often have poor prognosis. Alberta stroke program early CT score (ASPECTS) based on computerized tomography angiography source image (CTA-SI) can reflect the real cerebral perfusion more truly, and it can assess the size of core infarct more quickly and accurately, thus enabling to judge prognosis. 展开更多
关键词 Acute Ischemic stroke with large Vessel Occlusion Endovascular Therapy
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The regulatory variant rs17612742 confers the risk of large artery atherosclerotic stroke by increasing the expression of endothelin receptor type A
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作者 Di Luan Xing-Lun Dang +5 位作者 Xi Chen Zi-Xu Wang Shi-Fei Ye Yuan-Xiang Zhang Li-Li Yuan Kun Lian 《Life Research》 2022年第4期27-35,共9页
Genome-wide association studies have found that rs17612742 increases the risk of large artery atherosclerotic stroke.The rs17612742 was located in the intron region of Endothelin receptor type A(NRA),which was cellula... Genome-wide association studies have found that rs17612742 increases the risk of large artery atherosclerotic stroke.The rs17612742 was located in the intron region of Endothelin receptor type A(NRA),which was cellular and gender-heterogeneous.Functional genomics studies of rs17612742 were carried out through some public databases,and it was found that rs17612742 was located in the chromatin open region and promoted the expression of NRA.Compared with the control group,EDNRA expression increased in middle cerebral artery occlusion exposed rodents.However,age heterogeneity of EDNRA expression under physiological and pathological conditions was not observed.In addition,we also discussed how to conduct further empirical studies to provide evidence that rs17612742 confers the risk of large artery atherosclerotic stroke by increasing the expression of NRA. 展开更多
关键词 large artery atherosclerotic stroke rs17612742 EDNRA
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Coiled Polymer Artificial Muscles Having Dual-Mode Actuation with Large Stress Generation 被引量:1
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作者 Xinghao Hu Runmin Liu +5 位作者 Kai Zhao Yilun Wang Xianfu Bao Lin Xu Guanggui Cheng Jianning Ding 《Journal of Bionic Engineering》 SCIE EI CSCD 2023年第4期1626-1634,共9页
Coiled polymer artificial muscles with both large tensile stroke and giant force generation are needed for practical applications in robotics,soft exosuits,and prosthesis.However,most polymer yarn artificial muscles c... Coiled polymer artificial muscles with both large tensile stroke and giant force generation are needed for practical applications in robotics,soft exosuits,and prosthesis.However,most polymer yarn artificial muscles cannot generate a large force or stress.Here,we report an inexpensive Twisted and Coiled Polymer artificial muscle(TCP)that performs both large isobaric and isometric contractions.This TCP can generate a tensile stroke of 20.1%and a specific work capacity of up to 1.3 kJ kg^(−1) during temperature changes from 20 to 180℃.Moreover,the nylon yarn artificial muscle produced a reversible output stress of 28.4 MPa,which is 100 times larger than human skeletal muscle.A robot arm and a simple gripper were made to demonstrate the isobaric actuation and isometric actuation of our TCP muscle,repectivley.Thus,the polymer artificial muscles with dual-mode actuation show potential applications in the field of robotics,grippers,and exoskeletons and so on. 展开更多
关键词 Coiled nylon muscles Dual-mode actuation large stroke Stress generation
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Magnitude of systolic blood pressure reduction following endovascular treatment and clinical outcomes in acute large artery occlusion stroke
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作者 Xianjun Huang Xianhui Ding +6 位作者 Hao Wang Qiankun Cai Junfeng Xu Zibao Li Qian Yang Zhiming Zhou Jie Xu 《Stroke & Vascular Neurology》 2025年第2期224-231,共8页
Background The impact of lowering systolic blood pressure(SBP)following endovascular treatment(EVT)in acute large vessel occlusion stroke(LVOS)patients remains unclear.We aimed to explore the effect of the magnitude o... Background The impact of lowering systolic blood pressure(SBP)following endovascular treatment(EVT)in acute large vessel occlusion stroke(LVOS)patients remains unclear.We aimed to explore the effect of the magnitude of SBP reduction(SBPr)after EVT on outcomes in LVOS patients.Methods We consecutively registered patients at three comprehensive stroke centres who had experienced EVT as a result of acute anterior circulation LVOS.SBPr was calculated as follows:(baseline SBP−mean SBP/baseline SBP)×100%.The 90-day modified Rankin Scale score ranging from 0 to 2 was defined as a favourable functional outcome.Based on CT scans obtained within 24 hours after procedure,symptomatic intracranial haemorrhage(sICH)was assessed according to the criteria of the European Cooperative Acute Stroke Study III.Results We enrolled 1080 patients,of which 908(84.1%)had successful recanalisation.In the overall cohort,SBPr was correlated with lower odds of sICH(SBPr±10%as a reference,20%-30%:OR 0.460;95%CI:0.245 to 0.864;p=0.016;>30%:OR 0.304;95%CI 0.123 to 0.749;p=0.010).In patients who achieved successful reperfusion,SBPr>30%was correlated with higher odds of a poor outcome(SBPr±10%as a reference,OR 2.150;95%CI 1.268 to 3.645;p=0.004)and SBPr has a similar tendency towards reducing the incidence of sICH.In the subgroup analyses,baseline Alberta Stroke Programme Early CT(ASPECT)score(p_(interact)=0.024)modified the effect of SBPr on the 90-day outcome.Conclusion Among patients with EVT,a significant drop in SBP may be related to a poor functional outcome and a reduced incidence of sICH.Baseline ASPECT score may be an important interacting factor in the association of SBPr with the 90-day outcome.This study provides new insights for individualised BP management in patients with EVT. 展开更多
关键词 acute large artery occlusion stroke acute anterior circulation lvossbpr systolic blood pressure reduction large vessel occlusion clinical outcomes endovascular treatment endovascular treatment evt lowering systolic blood pressure sbp following
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Anaesthesia modality on endovascular therapy outcomes in patients with large infarcts:a post hoc analysis of the ANGEL-ASPECT trial
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作者 Fa Liang Kangda Zhang +9 位作者 Youxuan Wu Xinyan Wang Xuan Hou Yun Yu Yunzhen Wang Mengxing Wang Yuesong Pan Xiaochuan Huo Ruquan Han Zhongrong Miao 《Stroke & Vascular Neurology》 2025年第2期214-223,共10页
Objectives Endovascular therapy(EVT)now penetrates the once obscure realm of large infarct core volume acute ischaemic stroke(LICV-AIS).This research aimed to investigate the potential correlation between different an... Objectives Endovascular therapy(EVT)now penetrates the once obscure realm of large infarct core volume acute ischaemic stroke(LICV-AIS).This research aimed to investigate the potential correlation between different anaesthetic approaches and post-EVT outcomes in LICV-AIS patients.Methods Between October 2020 and May 2022,the China ANGEL-Alberta Stroke Programme Early CT Score(ASPECT)trial studied patients with LICV-AIS,randomly assigning them to the best medical management(BMM)or BMM with EVT.This post hoc subgroup analysis categorised subjects receiving BMM with EVT into general anaesthesia(GA)and non-GA groups based on anaesthesia type.We applied multivariable logistic regression to evaluate the relationship between anaesthesia during EVT and patient functional outcomes,as measured by the modified Rankin scale(mRS),in addition to the occurrence of complications.Further adjustment for selection bias was achieved through propensity score matching(PSM).Results In total,230 patients with LICV-AIS were enrolled(GA 84 vs Non-GA 146).No significant difference was observed between the two groups in terms of the proportion of patients who achieved an mRS score of 0-2 at 90 days(27.4%for the GA group vs 31.5%for the non-GA group,p=0.51).However,the GA group had significantly longer median surgical times(142 min vs 122 min,p=0.03).Furthermore,GA was associated with an increased risk of postoperative pneumonia(adjusted OR 2.03,95%CI 1.04 to 3.98).The results of PSM analysis agreed with the results of the multivariate regression analysis.No significant difference in intracranial haemorrhage incidence or mortality rate was observed between the groups.Conclusion This post hoc analysis of subgroups of the ANGEL-ASPECT trial suggested that there may be no significant association between the choice of anaesthesia and neurological outcomes in LICV-AIS patients.However,compared with non-GA,GA prolongs the duration of EVT and is associated with a greater postoperative pneumonia risk. 展开更多
关键词 modified rankin scale endovascular therapy evt now post hoc su investigate potential correlation large infarct core volume acute ischaemic stroke licv ais large infarct core volume acute ischaemic stroke endovascular therapy anaesthetic approaches
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A Precision Alignment Control Method of Linear Ultrasonic Motors Using the Normal Distribution Theory
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作者 ZHOU Liping SUN Zhijun +1 位作者 ZHANG Quan GUO Yu 《中国电机工程学报》 EI CSCD 北大核心 2012年第27期I0007-I0007,共1页
The linear ultrasonic motor(LUSM)has many merits such as high precision,quick response,self-locking when power off and so on.However,it also has some drawbacks such as strong non-linear and time-varying characteristic... The linear ultrasonic motor(LUSM)has many merits such as high precision,quick response,self-locking when power off and so on.However,it also has some drawbacks such as strong non-linear and time-varying characteristics,which are harmful to high precision positioning.Fig.1 shows a positioning stage driven by LUSMs.In this paper,the macro-micro control mode is adopted to realize the requirements of the large-workspace and high precision positioning.The switching macro-micro control depends on switching threshold,and it can be described as follows(E denotes the position error,D denotes switching threshold):When E>D,the PID based macro control method is adopted to realize large stroke and quick response;When E≤D,the normal distribution theory combined with the technology of fuzzy logic approach is employed to realize high precision positioning. 展开更多
关键词 linear ultrasonic motors(LUSM) positioning stage macro/micro drive large stroke precision positioning
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H型高血压合并大动脉粥样硬化型急性缺血性脑卒中血浆抗凝血酶3、高敏C-反应蛋白、载脂蛋白-B水平及其意义 被引量:2
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作者 程启慧 余丹 +1 位作者 杨国帅 孙荣道 《实用心脑肺血管病杂志》 2020年第S01期1-4,共4页
目的探讨大动脉粥样硬化型H型高血压(H-type hypertension,HH)合并急性缺血性脑卒中(Acute ischemic stroke,AIS)血浆抗凝血酶3(antithrombin,at3)、高敏C-反应蛋白(high-sensitivity C-reactive protein,hs-CRP)、载脂蛋白-B(apolipopr... 目的探讨大动脉粥样硬化型H型高血压(H-type hypertension,HH)合并急性缺血性脑卒中(Acute ischemic stroke,AIS)血浆抗凝血酶3(antithrombin,at3)、高敏C-反应蛋白(high-sensitivity C-reactive protein,hs-CRP)、载脂蛋白-B(apolipoprotein-B,ApoB)水平及与脑卒中发病的相关性。方法选取2017年2月—2017年6月期间在海口市人民医院神经内科住院汉族患者30例HH合并大动脉粥样硬化型AIS患者,在海口市人民医院体检中心门诊就诊的30例汉族HH患者及30例汉族健康对照人群。HH合并大动脉粥样硬化型AIS患者参照2014中国脑血管病防治指南的AIS诊断标准,血浆同型半胱氨酸(homocysteine,Hcy)>10μmol/L。对HH合并大动脉粥样硬化型AIS患者,据改良Rankin量表(Modified Rankin Scale,mRS)对预后进行评估:≤2分,示预后良好亚组,3~5分,示:预后不良亚组,采用ELISA试验检测试验对象及不同预后亚组血浆Hcy、at3、hs-CRP、ApoB等水平,分析不同对象血浆Hcy、at3、hs-CRP、ApoB水平,以评估血浆Hcy、at3、hs-CRP、ApoB高低对AIS发病的影响。结果HH合并大动脉粥样硬化型AIS组血浆at3水平(0.15±0.07)g/L及HH组血浆at3水平(0.17±0.11)g/L与对照组比较血浆at3水平(0.31±0.08)g/L显著降低(P<0.000),HH合并大动脉粥样硬化型AIS组血浆hs-CRP(8.83±1.58)mg/L及HH组血浆hs-CRP(7.99±1.43)mg/L与对照组血浆hs-CRP(5.81±1.16)mg/L比较,HH合并大动脉粥样硬化型AIS组血浆ApoB(2.33±0.45)g/L及HH组血浆ApoB(2.23±0.53)g/L与对照组血浆ApoB(0.84±0.41)g/L比较均显著升高(P<0.05),HH合并大动脉粥样硬化型AIS组与HH组比较血浆hs-CRP显著升高,血浆at3、ApoB水平无明显差异,HH合并大动脉粥样硬化型AIS患者不同预后亚组间比较预后不良亚组血浆Hcy(25.76±5.39)umol/L较预后良好亚组血浆Hcy水平(15.33±4.21)umol/l、预后不良亚组血浆hs-CRP(10.35±1.79)mg/l较预后良好亚组血浆hsCRP(8.37±1.36)mg/l水平显著升高(P<0.05),预后不良亚组血浆at3(0.14±0.08)g/L与预后良好亚组血浆at3(0.17±0.09)g/L、预后不良亚组ApoB(2.38±0.56)g/L与预后良好亚组血浆ApoB(2.28±0.43)g/L水平差异无统计学意义(P>0.05)。结论HH合并大动脉粥样硬化型AIS患者中血浆Hcy水平、hs-CRP水平升高可以影响预后,水平越高预后越差。at3不但参与急性脑卒中患者发病后被激活凝血酶的清除,at3还可能参与了HH患者慢性动脉粥样硬化的发生、发展,从而促进其大动脉粥样硬化型AIS的发病可能。CRP作用于内皮细胞,促进急性血栓形成和慢性动脉粥样硬化的进展,进而增加卒中的风险。HH患者ApoB的分泌,可使动脉粥样硬化恶化,促使HH相关大动脉粥样硬化型AIS的发病。 展开更多
关键词 H型高血压(H-type hypertension HH) 大动脉粥样硬化型急性缺血性脑卒中(large atherosclerotic acute ischemic stroke LA-AIS) 抗凝血酶(antithrombin at)3 高敏C-反应蛋白(high-sensitivity C-reactive protein hs-CRP) 载脂蛋白-B(apolipoprotein-B ApoB)
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