A convenient and efficient approach for difluoroalkyl-containing γ-hutyrolactones via the radical addition reaction of iododifluoromethyl ketones with 4-pentenoic acids initiated by AIBN in CH3CN at 60 ℃ was reporte...A convenient and efficient approach for difluoroalkyl-containing γ-hutyrolactones via the radical addition reaction of iododifluoromethyl ketones with 4-pentenoic acids initiated by AIBN in CH3CN at 60 ℃ was reported. Various difluoroalkyllcontaining γ-valerolactones were also synthesized under this reaction conditions.展开更多
基金financial supports from the National Natural Science Foundation of China(Nos.21472126,21172148,21302128)
文摘A convenient and efficient approach for difluoroalkyl-containing γ-hutyrolactones via the radical addition reaction of iododifluoromethyl ketones with 4-pentenoic acids initiated by AIBN in CH3CN at 60 ℃ was reported. Various difluoroalkyllcontaining γ-valerolactones were also synthesized under this reaction conditions.
