This paper is concerned with a class of nonlinear fractional differential equations with a disturbance parameter in the integral boundary conditions on the infinite interval.By using Guo-Krasnoselskii fixed point theo...This paper is concerned with a class of nonlinear fractional differential equations with a disturbance parameter in the integral boundary conditions on the infinite interval.By using Guo-Krasnoselskii fixed point theorem,fixed point index theory and the analytic technique,we give the bifurcation point of the parameter which divides the range of parameter for the existence of at least two,one and no positive solutions for the problem.And,by using a fixed point theorem of generalized concave operator and cone theory,we establish the maximum parameter interval for the existence of the unique positive solution for the problem and show that such a positive solution continuously depends on the parameter.In the end,some examples are given to illustrate our main results.展开更多
Extreme traffic loads significantly challenge the safety and cost-effectiveness of highway bridges,especially under site-specific traffic conditions.Conventional assessments often rely on overly conservative load mode...Extreme traffic loads significantly challenge the safety and cost-effectiveness of highway bridges,especially under site-specific traffic conditions.Conventional assessments often rely on overly conservative load models,leading to excessive structural design.In this study,a framework for the prediction of maximum bending moments in simply supported bridges is developed by integrating weigh-in-motion(WIM)data,traffic microsimulation,and generalized extreme value(GEV)regression modeling to establish relationships between the GEV parameters(μ,σ,ξ)and traffic factors—heavy vehicle proportion,bridge span length,vehicle speed,headway,and traffic volume.Using one-year WIM data from 7.4 million vehicles,the developed models for μ and σ exhibit high predictive accuracy(R^(2)>0.95)and are validated through leave-one-out cross-validation.The prediction of ξ is less accurate(R^(2)≈0.6),requiring further improvement.Applying these models to a 1000-year return level yields a reliable,data-driven extrapolation,supporting optimized bridge design and safety assessment under varying traffic conditions.展开更多
Weak measurement offers a powerful framework for probing nonclassical features of quantum mechanics,with anomalous weak values serving as operational signatures of contextuality.While the anomalous weak value verifica...Weak measurement offers a powerful framework for probing nonclassical features of quantum mechanics,with anomalous weak values serving as operational signatures of contextuality.While the anomalous weak value verification of quantum contextuality has been predominantly investigated in the single-photon regime and analyzed under approximation condition of infinitesimally small perturbation strength.This study releases the approximation condition and takes into account the impact of perturbation strength on the rigor of the verification.And the investigation on the verification of contextuality is extended to the multi-photon scenarios for observing the influence of the correlation between photons on the verification.Without the limitation of infinitesimally small probability of disturbance,anomalous weak values are identified as necessary for contextuality to emerge,thereby refining the criterion proposed by Pusey[Phys.Rev.Lett.113200401(2014)].In the multi-photon scenarios,the emergence of contextuality also depends strongly on both the photon number and the photon-number distribution state.In particular,contextuality is found to be maximized when the single-photon component dominates and the second-order correlation is lower.These results highlight the critical role of photon statistics in experimental tests of contextuality via anomalous weak values.展开更多
BACKGROUND:Although the Confusion Assessment Methods for the Intensive Care Unit(CAMICU) is a recommended tool for diagnosing sepsis-associated encephalopathy(SAE),it has several limitations.Mismatch-negativity(MMN) a...BACKGROUND:Although the Confusion Assessment Methods for the Intensive Care Unit(CAMICU) is a recommended tool for diagnosing sepsis-associated encephalopathy(SAE),it has several limitations.Mismatch-negativity(MMN) and P3a are components of event-related potentials(ERPs) used with electroencephalography(EEG) and are associated with cerebral function changes in critically ill patients.This study aimed to provide a quantitative,non-invasive method to guide SAE diagnosis in nonsedated patients.METHODS:From January 2022 to March 2023,sepsis patients without sedation were enrolled and assessed via the CAM-ICU,Glasgow Coma Scale(GCS),and ERP under standard procedures.Both MMN and P3a data were collected.The diagnostic value of MMN and P3a was assessed with processed ERP data.RESULTS:Thirty-six patients were included in this study,comprising 19 patients with SAE and 17 patients without SAE(NSAE).MMN and P3a amplitudes decreased,and only FzMMN amplitude significantly decreased in SAE patients(2.03 [1.08,2.93] mV vs.3.21 [1.92,4.34] mV,P=0.040).After median dichotomization,low F3P3a and FzP3a amplitudes were associated with higher CAM-ICU positivity rates and APACHE II scores.Both amplitude in F3P3a(AUC=0.710,95%CI:0.527–0.893,P=0.034) and FzP3a(AUC=0.700,95%CI:0.519–0.881,P=0.041) exhibited moderate diagnostic efficacy for SAE,while FzMMN amplitude lacks effective diagnostic value.CONCLUSION:In this pilot study,ERP components F3P3a and FzP3a amplitudes demonstrated moderate diagnostic value for SAE.These exploratory findings require confirmation in larger and powered cohorts.展开更多
Solar-driven H_(2) production coupled with selective organic transformation represents a promising strategy for co-generation of green hydrogen and high-value chemicals,yet its feasibility relies critically on effecti...Solar-driven H_(2) production coupled with selective organic transformation represents a promising strategy for co-generation of green hydrogen and high-value chemicals,yet its feasibility relies critically on effective bifunctional photocatalysts.Herein,we report the synthesis of ultrafine Cd_(x)Zn_(1-x)S nanocrystals derived from a zeolitic imidazolate framework(ZIF),featuring high surface area,shortened charge diffusion path,and enhanced H_(2) evolution activity.Anchoring amorphous Pt sub-nanoclusters onto these nanocrystals created a bifunctional catalyst(Pt-Cd_(x)Zn_(1-x)S)for efficient lactic acid photoreforming,enabling coproduction of H_(2) with switchable selectivity toward pyruvic acid(PA)or 2,3-dihydroxy-2,3-dimethylsuccinic acid(DTA).The optimized 0.5Pt-Cd_(0.3)Zn_(0.7)S catalyst achieved an exceptional H_(2) production rate of 270.6 mmol h^(-1) g^(-1),73.1%PA selectivity,and 62.8% apparent quantum efficiency at 400 nm.Mechanistic studies revealed that lactic acid undergoes C-H cleavage to form carbon-centered radicals.Pt sub-nanoclusters served as electron sinks to facilitate O-H dissociation and PA formation,whereas pristine Cd_(0.3)Zn_(0.6)7S promoted direct C-C coupling of radicals to predominantly yield DTA.This work offers critical insights for designing advanced bifunctional photocatalysts to integrate solar hydrogen and value-added chemical synthesis.展开更多
Lhasa,one of the world's highest cities,confronts the challenge of harmonizing cultural heritage preservation with ecological protection.Assessing the spatiotemporal dynamics of ecosystem service value(ESV)in its ...Lhasa,one of the world's highest cities,confronts the challenge of harmonizing cultural heritage preservation with ecological protection.Assessing the spatiotemporal dynamics of ecosystem service value(ESV)in its central urban area is therefore critical for informing future urban planning and land management.This study systematically analyzed land use evolution,the spatiotemporal characteristics of ecosystem services,and ecological network construction within Lhasa's central urban area.It integrated multi-source data,including Landsat remote sensing imagery from 2000,2010,and 2023,with multiple modeling methods such as the InVEST model,MaxEnt for cultural service assessment,the Minimum Cumulative Resistance(MCR)model,and circuit theory.Based on these analyses,optimization strategies were proposed.The results indicate that from 2000 to 2023,areas of cultivated land,grassland,and water bodies decreased by 7.47%,6.85%,and 0.68%,respectively,while wetland and forest areas expanded by 1.44%and 0.64%.Construction land exhibited significant expansion(12.94%),leading to an overall ESV reduction of 462.8×10^(5)yuan.Vegetation coverage was identified as the pivotal factor influencing ESV distribution,with higher values concentrated in the Lhasa River Basin and near the Lhalu Wetland,diminishing towards the urban core.Furthermore,spatial autocorrelation analysis revealed significant positive spatial clustering,with low-low aggregation in the eastern and central regions and high-high aggregation in the Lhasa River Basin and its surrounding water bodies.Moreover,based on a comprehensive ecosystem service assessment,11 ecological source sites were identified,primarily in the southwestern mountains and northeastern foothills.A comprehensive resistance surface,incorporating factors such as elevation,Normalized Difference Vegetation Index(NDVI),and land use,facilitated the extraction of 23 potential ecological corridors totaling 124.96 km in length.Topological network analysis indicated high redundancy and connectivity;however,marginal source sites relying on single connections exhibited significant vulnerability to rupture.Additionally,the application of circuit theory identified 30 ecological pinch points(current density≥1.5 A/km^(2))and 23 obstacle points,revealing significant blockages to ecological flow along the Qinghai-Xizang Highway,within the old city,and in other areas of high-intensity human activity.To address the identified network deficiencies—‘scattered cores,fragmented corridors,and insufficient resilience’—this study proposes an optimization strategy conceptualized as‘one vein,three corridors,and multiple cores’.Recommendations for enhancing network resilience include the delineation of ecological protection red lines,the integration of plateau-adapted technologies,and the fostering of community governance mechanisms.This approach aims to provide a scientific basis for constructing an ecological security pattern and promoting sustainable development in plateau cities.Ultimately,this research contributes to the enhancement of ecological well-being in the Himalayan region.展开更多
Against the backdrop of profound restructuring in the global industrial and supply chains,data elements have emerged as a critical force driving the transformation of enterprises'new quality productive forces.To a...Against the backdrop of profound restructuring in the global industrial and supply chains,data elements have emerged as a critical force driving the transformation of enterprises'new quality productive forces.To address the ambiguity surrounding its micro-level empowerment mechanism,this paper empirically examines the impact of data elements on enterprises'new quality productive forces and its transmission channels using panel data of Chinese A-share listed firms from 2014 to 2023.The results show that data elements significantly improve the level of enterprises'new quality productive forces.Heterogeneity analysis indicates that this promotional effect is more pronounced in non-state-owned enterprises,large-scale enterprises,and low-leverage enterprises.Mechanism tests confirm that data elements empower new quality productive forces through three paths:enhancing enterprise innovation capability,improving internal operational efficiency,and promoting inter-firm collaboration efficiency.This study provides empirical evidence for understanding the micro-level empowerment logic of data elements and offers theoretical references and practical implications for advancing the deep integration of the digital economy and the real economy.展开更多
AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control stu...AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control study included participants who underwent routine complete blood count testing.Inflammation-related indices,including neutrophil-to-lymphocyte ratio,systemic immune-inflammation index(SII),and PIV,were derived and analyzed.Receiver operating characteristic curve(ROC)analysis was applied to assess the diagnostic performance of these indices in distinguishing patients with PDR,with sensitivity,specificity,area under ROC,and optimal threshold values calculated.In addition,binary logistic regression analysis was performed to evaluate the association between inflammatory indices and PDR stage.RESULTS:This study included 205 patients:60 with diabetes without retinopathy(mean age:61.81±10.76y),80 with PDR(mean age:61.63±10.03y)and 65 healthy controls(mean age:59.52±5.88y).The PDR group had significantly higher white blood cell(WBC,P<0.001),monocyte(MONO,P=0.009)and neutrophil(NEU)counts(P<0.001).SII and PIV had the highest sensitivity and area under ROC for predicting patients with PDR(0.822,0.846,respectively).The optimal cut-off values for discriminating patients with PDR were determined to be>527.12 and>299.08 for SII and PIV,respectively.The logistic regression analysis demonstrated that a decrease in lymphocyte(LYM)count and an increase in platelet count(PLT),glycated haemoglobin(HbA1c),SII,and PIV were all significantly associated with the development of high-risk PDR(all P<0.05).PIV was more stable than independent MONO,LYM,PLT and NEU levels in predicting both the diagnosis and stage of PDR.The optimal cut-off value for PIV to discriminate patients with high-risk PDR was found to be>345.87 area under ROC=0.871,with sensitivity of 0.827 and specificity of 0.812.CONCLUSION:PIV is a reliable,valuable,and inexpensive blood index that can be used for early detection and staging of PDR.PIV may therefore be essential to be used for the follow-up of diabetic patients.展开更多
The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation...The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation and evolution of Meizhou pomelo industry cluster in China,focusing on its role in restructuring rural socio-economic systems and integrating the whole value chains.Based on a case study employing qualitative methods such as in-depth interviews and participatory observation,the agricultural cluster evolution of Meizhou pomelo was categorized into three key phases of initial decentralization,self-organized scaling,and reorganized clustering.Geographical proximity and industrial agglomeration constitute the physical foundation,while vertical/horizontal linkages,technologic-al innovation,and policy support enhance competitiveness.Special mechanisms emerge through localized social networks,farmer co-operatives’activation,and cross-regional market expansion.The cluster’s impact is manifested in the shift from extensive to standard-ized and modernized production,diversified and flexible livelihood of farmers,and the integration of agriculture with industry and ser-vices.The development of the whole value chain based on agricultural cluster represents a critical pathway for achieving agricultural modernization,encompassing both internal and external value chain optimization.Through quality assurance systems,product diversi-fication strategies,operational efficiency improvements,and brand enhancement,these clusters amplify product value propositions and market competitiveness.This systemic approach facilitates supply-demand coordination,enables resource synergies,and optimizes eco-nomic returns across the horizontal and vertical value chain.This paper argues that agricultural clusters serve as strategic catalysts for sustainable rural development by reconstructing local production systems,fostering innovation ecosystems,and aligning agricultural modernization.It contributes to debates on rural vitalization by demonstrating how agricultural clustering can reconfigure rural areas as hubs of ecological modernization,rather than mere urban peripheries.展开更多
In this paper,we study the nonlinear Riemann boundary value problem with square roots that is represented by a Cauchy-type integral with kernel density in variable exponent Lebesgue spaces.We discuss the odd-order zer...In this paper,we study the nonlinear Riemann boundary value problem with square roots that is represented by a Cauchy-type integral with kernel density in variable exponent Lebesgue spaces.We discuss the odd-order zero-points distribution of the solutions and separate the single valued analytic branch of the solutions with square roots,then convert the problem to a Riemann boundary value problem in variable exponent Lebesgue spaces and discuss the singularity of solutions at individual zeros belonging to curve.We consider two types of cases those where the coefficient is Hölder and those where it is piecewise Hölder.Then we solve the Hilbert boundary value problem with square roots in variable exponent Lebesgue spaces.By discussing the distribution of the odd-order zero-points for solutions and the method of symmetric extension,we convert the Hilbert problem to a Riemann boundary value problem.The equivalence of the transformation is discussed.Finally,we get the solvable conditions and the direct expressions of the solutions in variable exponent Lebesgue spaces.展开更多
In the Tianshan region,a complete textile industry chain has been established,covering the entire process from cotton cultivation and chemical fiber production,through spinning,weaving,dyeing,and finishing,and further...In the Tianshan region,a complete textile industry chain has been established,covering the entire process from cotton cultivation and chemical fiber production,through spinning,weaving,dyeing,and finishing,and further extending to apparel,home textiles,and industrial textiles.In November 2025,the first list of five characteristic textile and apparel industry clusters in Xinjiang was officially announced,marking a new stage in the clustering of Xinjiang's textile and apparel industry.Data shows that the total output value of Xinjiang's cotton and textile and apparel industry chain has exceeded 220 billion yuan.With the nation's largest cotton production,a complete industrial chain system,and strong synergistic effects,Xinjiang has become a leading and highly competitive textile industry hub in China.展开更多
The Double Take column looks at a single topic from an African and Chinese perspective.This month,we discuss how to understand the growing emphasis on emotional returns among young people.Emotional value has emerged a...The Double Take column looks at a single topic from an African and Chinese perspective.This month,we discuss how to understand the growing emphasis on emotional returns among young people.Emotional value has emerged as a central force shaping youth decision-making across work,consumption,relationships and lifestyle choices.Unlike traditional economic rationality that prioritises income and material security,emotional value focuses on how choices make individuals feel and how they align with personal meaning.This shift is particularly evident in rapidly transforming societies such as China and Ghana,where economic restructuring,globalisation and social change have reshaped pathways to adulthood.展开更多
Ming-style furniture represents the pinnacle of Chinese traditional furniture,with the four-head official’s cap chair standing out as a representative category due to its classic form and cultural connotations.This p...Ming-style furniture represents the pinnacle of Chinese traditional furniture,with the four-head official’s cap chair standing out as a representative category due to its classic form and cultural connotations.This paper takes a specific rosewood four-head official’s cap chair inscribed by Wang Shixiang as the research subject,employing a tripartite approach of form analysis,material examination,and inscription interpretation.The chair strictly adheres to the classic form of Ming-style four-head official’s cap chairs,embodying the Ming Dynasty design philosophy of“the unity of function and aesthetics”.The scarcity and unique grain pattern of the golden-flecked rosewood(Zitan)endow it with the status of“gold among woods”.Wang Shixiang’s inscription binds the furniture to the cultural essence of“the charm of the Ming Dynasty”,transforming it into“heritable cultural heritage”.This paper provides a new perspective for the case study of Ming-style furniture and offers theoretical reference for the contemporary inheritance of traditional craftsmanship.展开更多
The Nuo mask is the core visual vehicle within China’s Nuo culture and constitutes a complex symbolic system through facial features(icons),patterns(indexes),and colors(symbols).Within the context of intangible cultu...The Nuo mask is the core visual vehicle within China’s Nuo culture and constitutes a complex symbolic system through facial features(icons),patterns(indexes),and colors(symbols).Within the context of intangible cultural heritage(ICH)preservation,its value lies in the continuation and revitalization of its dynamic symbolic functions.Grounded in semiotic theory,this paper elaborates on three core dimensions of symbolic value manifested by Nuo masks in ICH preservation:a ritual symbol for living transmission,a symbol of identity for collective memory,and an aesthetic symbol as a source of creativity.展开更多
The Transformer has achieved great success in the field of medical image segmentation,but its quadratic computational complexity limits its application in dense medical image prediction.Recently,the receptance weighte...The Transformer has achieved great success in the field of medical image segmentation,but its quadratic computational complexity limits its application in dense medical image prediction.Recently,the receptance weighted key value(RWKV)architecture has garnered widespread attention due to its linear computational complexity and its capability of parallel computation during training.Despite the RWKV model's proficiency in addressing long-range modeling tasks with linear computational complexity,most current RWKV-based approaches employ static scanning patterns.These patterns may inadvertently incorporate biased prior knowledge into the model's predictions.To address this challenge,we propose a multi-head scan strategy combined with padding methods to effectively simulate spatial continuity in 2D images.Within the Feature Aggregation Attention(FAA)module,asymmetric convolutions are designed to aggregate 1D sequence features along a single dimension,thereby expanding effective receptive fields while preserving structural sparsity.Additionally,panoramic token shift(P-Shift)effectively models local dependency relationships by moving tokens from a wide receptive field.Extensive experiments conducted on the ISIC17/18 and ACDC datasets demonstrate that our method exhibits superior performance in dense medical image prediction tasks.展开更多
Numerous economically underdeveloped and ecologically fragile areas in southern China's mountainous regions face increasing challenges in achieving sustainable development. A comparative analysis of ecosystem serv...Numerous economically underdeveloped and ecologically fragile areas in southern China's mountainous regions face increasing challenges in achieving sustainable development. A comparative analysis of ecosystem service responses to land use scenarios, incorporating adaptive valuation coefficients, can reveal actionable pathways to reconcile sustainable development and ecological conservation in mountainous regions. In this study, the ecosystem service value(ESV) dynamics in the Hunan–Jiangxi Border Region(HJBR), which is a representative old revolutionary base with a relatively undeveloped economy, were investigated by integrating historical land use data analysis from 2000 to 2020 and adopting patch-generating land use simulation(PLUS) modelling. Three policy-responsive scenarios, namely, natural growth(NGS), farmland protection(FPS), and ecological protection(EPS), were systematically developed to project ESV variations for 2030 and 2040. Our analysis revealed that from 2000 to 2020, urban sprawl and water body expansion occurred at the expense of forestland, cultivated land, and grassland, yet yield-driven productivity improvements increased the ESV by 227.30%(equivalent to ¥250.0 billion). By 2040, the NGS achieves the greatest ESV increase(¥189.895 billion) while fully accommodating urban land demand;the FPS yields the smallest ESV increase(¥148.169 billion), with the EPS occupying an intermediate position(¥182.207 billion). Climate regulation and hydrological services dominate ecological functions, collectively exceeding 49% across all the scenarios and periods. By 2040, most service functions exhibit growth trends except for a 0.30% water supply decline under the FPS, whereas the EPS demonstrates balanced development through multidimensional service enhancements. These findings underscore the necessity of integrating ecological safeguards into land use planning frameworks to ensure sustainable regional development.展开更多
The rapid population and land urbanization not only promoted economic development but also affected the ecosystem service value(ESV).In the context of new-type urbanization and green development,it’s essential to inv...The rapid population and land urbanization not only promoted economic development but also affected the ecosystem service value(ESV).In the context of new-type urbanization and green development,it’s essential to investigate the impacts of urbanization on ESV in China.However,a comprehensive and dynamic framework to reveal the relationship between ESV and urbanization processes is lacking.This study adopted multi-source datasets to portray China’s urbanization process by integrating population,land,and economic urbanization,eval-uated the ESV changes of 10 categories by gross ecosystem product(GEP)methods,and explored ESV changes within different urbanization scales and speeds.The results showed rapid urbanization in the population,land,and economic dimensions in China,with a faster process of economic urbanization.The ESV also exhibited an increasing trend,with higher levels in the southeastern coastal regions and lower levels in the northwestern regions.Urbanization had positive impacts on ESV across various research units,but the ESV exhibited heteroge-neous changes across different urbanization scales,speeds,and their interactive effects.The response of ESV to dynamic urbanization processes was influenced by socio-economic,ecological,and policy factors;it is essential to combine targeted measures with general ecological product value realization methods in each unit to maximize social-economic-ecological benefits.展开更多
BACKGROUND Acute-on-chronic liver failure(ACLF)is a liver disease based on chronic liver disease,which is significantly influenced by clinical treatment regimen and disease status,and despite the existence of multiple...BACKGROUND Acute-on-chronic liver failure(ACLF)is a liver disease based on chronic liver disease,which is significantly influenced by clinical treatment regimen and disease status,and despite the existence of multiple prognostic assessment indicators for ACLF,the overall sensitivity and accuracy are relatively low.AIM To investigate the prognostic value of the combined detection of alpha-fetoprotein(AFP),plasma prothrombin activity(PTA),and serum prealbumin(PA)in ACLF.METHODS This retrospective study included 87 patients with ACLF admitted from February 2021 to February 2023 and categorized them into the survival(n=47)and death(n=40)groups according to their clinical outcomes 3 months posttreatment.All the participants underwent AFP,PTA,and PA level measurements upon admission.Baseline data,as well as AFP,PTA,and PA levels,were comparatively analyzed.Pearson correlation coefficients were utilized to analyze the correlations of AFP,PTA,and PA with different survival outcomes in patients with ACLF.Receiver operating characteristic(ROC)curves and areas under the curves were used to evaluate the predictive value of AFP,PTA,and PA for ACLF prognosis.RESULTS AFP,PTA,and PA levels were markedly decreased in the death group than in the survival group(P<0.05).Pearson analysis indicated a positive association of the AFP,PTA,and PA levels with the survival of patients with ACLF(P<0.05).ROC curve analysis determined the sensitivity and specificity of the combined diagnosis at 91.24%and 100.00%,respectively,both of which were notably increased compared to the single-index diagnosis.The ROC of their combined diagnosis was 0.989,significantly surpassing 0.907,0.849,and 0.853 of AFP,PTA,and PA,respectively.No statistically significant variance was determined in the sensitivity and specificity of the combined diagnosis vs the single detection(P>0.05).CONCLUSION The combined detection of AFP,PTA,and PA levels demonstrates favorable diagnostic value for the short-term prognosis of patients with ACLF,featuring high sensitivity and specificity.展开更多
基金Supported by the National Natural Science Foundation of China(11361047)Fundamental Research Program of Shanxi Province(20210302124529)。
文摘This paper is concerned with a class of nonlinear fractional differential equations with a disturbance parameter in the integral boundary conditions on the infinite interval.By using Guo-Krasnoselskii fixed point theorem,fixed point index theory and the analytic technique,we give the bifurcation point of the parameter which divides the range of parameter for the existence of at least two,one and no positive solutions for the problem.And,by using a fixed point theorem of generalized concave operator and cone theory,we establish the maximum parameter interval for the existence of the unique positive solution for the problem and show that such a positive solution continuously depends on the parameter.In the end,some examples are given to illustrate our main results.
基金The National Natural Science Foundation of China(No.52278149)the Natural Science Foundation of Jiangsu Province(No.BZ2024015)+1 种基金the Opening Project of State Key Laboratory for Track Technology of High-Speed Railway(No.2023YJ375)the Opening Project of Zhejiang Engineering Centre of Road and Bridge Intelligent Operation and Maintenance Technology(No.202402G).
文摘Extreme traffic loads significantly challenge the safety and cost-effectiveness of highway bridges,especially under site-specific traffic conditions.Conventional assessments often rely on overly conservative load models,leading to excessive structural design.In this study,a framework for the prediction of maximum bending moments in simply supported bridges is developed by integrating weigh-in-motion(WIM)data,traffic microsimulation,and generalized extreme value(GEV)regression modeling to establish relationships between the GEV parameters(μ,σ,ξ)and traffic factors—heavy vehicle proportion,bridge span length,vehicle speed,headway,and traffic volume.Using one-year WIM data from 7.4 million vehicles,the developed models for μ and σ exhibit high predictive accuracy(R^(2)>0.95)and are validated through leave-one-out cross-validation.The prediction of ξ is less accurate(R^(2)≈0.6),requiring further improvement.Applying these models to a 1000-year return level yields a reliable,data-driven extrapolation,supporting optimized bridge design and safety assessment under varying traffic conditions.
基金Project supported by the National Natural Science Foun-dation of China(Grant Nos.62371199 and 62071186)the Natural Science Foundation of Guangdong Province,China(Grant No.2024A1515012427)+1 种基金the Quantum Science Strate-gic Initiative Project of Guangdong Province,China(Grant No.GDZX2305001)the Key Laboratory Project of Guangdong Province,China(Grant No.2020B1212060066).
文摘Weak measurement offers a powerful framework for probing nonclassical features of quantum mechanics,with anomalous weak values serving as operational signatures of contextuality.While the anomalous weak value verification of quantum contextuality has been predominantly investigated in the single-photon regime and analyzed under approximation condition of infinitesimally small perturbation strength.This study releases the approximation condition and takes into account the impact of perturbation strength on the rigor of the verification.And the investigation on the verification of contextuality is extended to the multi-photon scenarios for observing the influence of the correlation between photons on the verification.Without the limitation of infinitesimally small probability of disturbance,anomalous weak values are identified as necessary for contextuality to emerge,thereby refining the criterion proposed by Pusey[Phys.Rev.Lett.113200401(2014)].In the multi-photon scenarios,the emergence of contextuality also depends strongly on both the photon number and the photon-number distribution state.In particular,contextuality is found to be maximized when the single-photon component dominates and the second-order correlation is lower.These results highlight the critical role of photon statistics in experimental tests of contextuality via anomalous weak values.
基金supported by the CAMS Innovation Fund for Medical Sciences (CIFMS)(No.2021-1-I2M-020)National High Level Hospital Clinical Research Funding (No.2022-PUMCH-B-109)National Natural Science Foundation of China (82402543)。
文摘BACKGROUND:Although the Confusion Assessment Methods for the Intensive Care Unit(CAMICU) is a recommended tool for diagnosing sepsis-associated encephalopathy(SAE),it has several limitations.Mismatch-negativity(MMN) and P3a are components of event-related potentials(ERPs) used with electroencephalography(EEG) and are associated with cerebral function changes in critically ill patients.This study aimed to provide a quantitative,non-invasive method to guide SAE diagnosis in nonsedated patients.METHODS:From January 2022 to March 2023,sepsis patients without sedation were enrolled and assessed via the CAM-ICU,Glasgow Coma Scale(GCS),and ERP under standard procedures.Both MMN and P3a data were collected.The diagnostic value of MMN and P3a was assessed with processed ERP data.RESULTS:Thirty-six patients were included in this study,comprising 19 patients with SAE and 17 patients without SAE(NSAE).MMN and P3a amplitudes decreased,and only FzMMN amplitude significantly decreased in SAE patients(2.03 [1.08,2.93] mV vs.3.21 [1.92,4.34] mV,P=0.040).After median dichotomization,low F3P3a and FzP3a amplitudes were associated with higher CAM-ICU positivity rates and APACHE II scores.Both amplitude in F3P3a(AUC=0.710,95%CI:0.527–0.893,P=0.034) and FzP3a(AUC=0.700,95%CI:0.519–0.881,P=0.041) exhibited moderate diagnostic efficacy for SAE,while FzMMN amplitude lacks effective diagnostic value.CONCLUSION:In this pilot study,ERP components F3P3a and FzP3a amplitudes demonstrated moderate diagnostic value for SAE.These exploratory findings require confirmation in larger and powered cohorts.
基金supported by the National Natural Science Foundation of China(Grant 52276212)the National Key Research and Development Program of China(Grant 2022YFB3803600)+1 种基金the Natural Science Foundation of Jiangsu Province(Grant BK20231211)the China Fundamental Research Funds for the Central Universities.
文摘Solar-driven H_(2) production coupled with selective organic transformation represents a promising strategy for co-generation of green hydrogen and high-value chemicals,yet its feasibility relies critically on effective bifunctional photocatalysts.Herein,we report the synthesis of ultrafine Cd_(x)Zn_(1-x)S nanocrystals derived from a zeolitic imidazolate framework(ZIF),featuring high surface area,shortened charge diffusion path,and enhanced H_(2) evolution activity.Anchoring amorphous Pt sub-nanoclusters onto these nanocrystals created a bifunctional catalyst(Pt-Cd_(x)Zn_(1-x)S)for efficient lactic acid photoreforming,enabling coproduction of H_(2) with switchable selectivity toward pyruvic acid(PA)or 2,3-dihydroxy-2,3-dimethylsuccinic acid(DTA).The optimized 0.5Pt-Cd_(0.3)Zn_(0.7)S catalyst achieved an exceptional H_(2) production rate of 270.6 mmol h^(-1) g^(-1),73.1%PA selectivity,and 62.8% apparent quantum efficiency at 400 nm.Mechanistic studies revealed that lactic acid undergoes C-H cleavage to form carbon-centered radicals.Pt sub-nanoclusters served as electron sinks to facilitate O-H dissociation and PA formation,whereas pristine Cd_(0.3)Zn_(0.6)7S promoted direct C-C coupling of radicals to predominantly yield DTA.This work offers critical insights for designing advanced bifunctional photocatalysts to integrate solar hydrogen and value-added chemical synthesis.
基金National Natural Science Foundation of China Youth Fund Project:Research on the Construction of Ecological Security Pattern in the Transition Zone of Nature Reserves along the Sichuan-Xizang Railway(Western Sichuan Section)(51908470).
文摘Lhasa,one of the world's highest cities,confronts the challenge of harmonizing cultural heritage preservation with ecological protection.Assessing the spatiotemporal dynamics of ecosystem service value(ESV)in its central urban area is therefore critical for informing future urban planning and land management.This study systematically analyzed land use evolution,the spatiotemporal characteristics of ecosystem services,and ecological network construction within Lhasa's central urban area.It integrated multi-source data,including Landsat remote sensing imagery from 2000,2010,and 2023,with multiple modeling methods such as the InVEST model,MaxEnt for cultural service assessment,the Minimum Cumulative Resistance(MCR)model,and circuit theory.Based on these analyses,optimization strategies were proposed.The results indicate that from 2000 to 2023,areas of cultivated land,grassland,and water bodies decreased by 7.47%,6.85%,and 0.68%,respectively,while wetland and forest areas expanded by 1.44%and 0.64%.Construction land exhibited significant expansion(12.94%),leading to an overall ESV reduction of 462.8×10^(5)yuan.Vegetation coverage was identified as the pivotal factor influencing ESV distribution,with higher values concentrated in the Lhasa River Basin and near the Lhalu Wetland,diminishing towards the urban core.Furthermore,spatial autocorrelation analysis revealed significant positive spatial clustering,with low-low aggregation in the eastern and central regions and high-high aggregation in the Lhasa River Basin and its surrounding water bodies.Moreover,based on a comprehensive ecosystem service assessment,11 ecological source sites were identified,primarily in the southwestern mountains and northeastern foothills.A comprehensive resistance surface,incorporating factors such as elevation,Normalized Difference Vegetation Index(NDVI),and land use,facilitated the extraction of 23 potential ecological corridors totaling 124.96 km in length.Topological network analysis indicated high redundancy and connectivity;however,marginal source sites relying on single connections exhibited significant vulnerability to rupture.Additionally,the application of circuit theory identified 30 ecological pinch points(current density≥1.5 A/km^(2))and 23 obstacle points,revealing significant blockages to ecological flow along the Qinghai-Xizang Highway,within the old city,and in other areas of high-intensity human activity.To address the identified network deficiencies—‘scattered cores,fragmented corridors,and insufficient resilience’—this study proposes an optimization strategy conceptualized as‘one vein,three corridors,and multiple cores’.Recommendations for enhancing network resilience include the delineation of ecological protection red lines,the integration of plateau-adapted technologies,and the fostering of community governance mechanisms.This approach aims to provide a scientific basis for constructing an ecological security pattern and promoting sustainable development in plateau cities.Ultimately,this research contributes to the enhancement of ecological well-being in the Himalayan region.
文摘Against the backdrop of profound restructuring in the global industrial and supply chains,data elements have emerged as a critical force driving the transformation of enterprises'new quality productive forces.To address the ambiguity surrounding its micro-level empowerment mechanism,this paper empirically examines the impact of data elements on enterprises'new quality productive forces and its transmission channels using panel data of Chinese A-share listed firms from 2014 to 2023.The results show that data elements significantly improve the level of enterprises'new quality productive forces.Heterogeneity analysis indicates that this promotional effect is more pronounced in non-state-owned enterprises,large-scale enterprises,and low-leverage enterprises.Mechanism tests confirm that data elements empower new quality productive forces through three paths:enhancing enterprise innovation capability,improving internal operational efficiency,and promoting inter-firm collaboration efficiency.This study provides empirical evidence for understanding the micro-level empowerment logic of data elements and offers theoretical references and practical implications for advancing the deep integration of the digital economy and the real economy.
文摘AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control study included participants who underwent routine complete blood count testing.Inflammation-related indices,including neutrophil-to-lymphocyte ratio,systemic immune-inflammation index(SII),and PIV,were derived and analyzed.Receiver operating characteristic curve(ROC)analysis was applied to assess the diagnostic performance of these indices in distinguishing patients with PDR,with sensitivity,specificity,area under ROC,and optimal threshold values calculated.In addition,binary logistic regression analysis was performed to evaluate the association between inflammatory indices and PDR stage.RESULTS:This study included 205 patients:60 with diabetes without retinopathy(mean age:61.81±10.76y),80 with PDR(mean age:61.63±10.03y)and 65 healthy controls(mean age:59.52±5.88y).The PDR group had significantly higher white blood cell(WBC,P<0.001),monocyte(MONO,P=0.009)and neutrophil(NEU)counts(P<0.001).SII and PIV had the highest sensitivity and area under ROC for predicting patients with PDR(0.822,0.846,respectively).The optimal cut-off values for discriminating patients with PDR were determined to be>527.12 and>299.08 for SII and PIV,respectively.The logistic regression analysis demonstrated that a decrease in lymphocyte(LYM)count and an increase in platelet count(PLT),glycated haemoglobin(HbA1c),SII,and PIV were all significantly associated with the development of high-risk PDR(all P<0.05).PIV was more stable than independent MONO,LYM,PLT and NEU levels in predicting both the diagnosis and stage of PDR.The optimal cut-off value for PIV to discriminate patients with high-risk PDR was found to be>345.87 area under ROC=0.871,with sensitivity of 0.827 and specificity of 0.812.CONCLUSION:PIV is a reliable,valuable,and inexpensive blood index that can be used for early detection and staging of PDR.PIV may therefore be essential to be used for the follow-up of diabetic patients.
基金Under the auspices of the Key Projects of Philosophy and Social Sciences Research,Ministry of Education of China(No.23JZD008)National Natural Science Foundation of China(No.42171193)+2 种基金Key Project of Guangdong Provincial Philosophy and Social Sciences Planning(No.GD24ES013,GD25ZX04)2025 Guangzhou Basic and Applied Basic Research Special Project(No.2025A04J7127)Fundamental Research Funds for the Central Universities,Sun Yat-sen University(No.24wkjc11)。
文摘The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation and evolution of Meizhou pomelo industry cluster in China,focusing on its role in restructuring rural socio-economic systems and integrating the whole value chains.Based on a case study employing qualitative methods such as in-depth interviews and participatory observation,the agricultural cluster evolution of Meizhou pomelo was categorized into three key phases of initial decentralization,self-organized scaling,and reorganized clustering.Geographical proximity and industrial agglomeration constitute the physical foundation,while vertical/horizontal linkages,technologic-al innovation,and policy support enhance competitiveness.Special mechanisms emerge through localized social networks,farmer co-operatives’activation,and cross-regional market expansion.The cluster’s impact is manifested in the shift from extensive to standard-ized and modernized production,diversified and flexible livelihood of farmers,and the integration of agriculture with industry and ser-vices.The development of the whole value chain based on agricultural cluster represents a critical pathway for achieving agricultural modernization,encompassing both internal and external value chain optimization.Through quality assurance systems,product diversi-fication strategies,operational efficiency improvements,and brand enhancement,these clusters amplify product value propositions and market competitiveness.This systemic approach facilitates supply-demand coordination,enables resource synergies,and optimizes eco-nomic returns across the horizontal and vertical value chain.This paper argues that agricultural clusters serve as strategic catalysts for sustainable rural development by reconstructing local production systems,fostering innovation ecosystems,and aligning agricultural modernization.It contributes to debates on rural vitalization by demonstrating how agricultural clustering can reconfigure rural areas as hubs of ecological modernization,rather than mere urban peripheries.
基金supported by the National Natural Science Foundation of China(11601525)the Natural Science Foundation of Hunan Province(2024JJ5412),the Changsha Municipal Natural Science Foundation(kq2402193).
文摘In this paper,we study the nonlinear Riemann boundary value problem with square roots that is represented by a Cauchy-type integral with kernel density in variable exponent Lebesgue spaces.We discuss the odd-order zero-points distribution of the solutions and separate the single valued analytic branch of the solutions with square roots,then convert the problem to a Riemann boundary value problem in variable exponent Lebesgue spaces and discuss the singularity of solutions at individual zeros belonging to curve.We consider two types of cases those where the coefficient is Hölder and those where it is piecewise Hölder.Then we solve the Hilbert boundary value problem with square roots in variable exponent Lebesgue spaces.By discussing the distribution of the odd-order zero-points for solutions and the method of symmetric extension,we convert the Hilbert problem to a Riemann boundary value problem.The equivalence of the transformation is discussed.Finally,we get the solvable conditions and the direct expressions of the solutions in variable exponent Lebesgue spaces.
文摘In the Tianshan region,a complete textile industry chain has been established,covering the entire process from cotton cultivation and chemical fiber production,through spinning,weaving,dyeing,and finishing,and further extending to apparel,home textiles,and industrial textiles.In November 2025,the first list of five characteristic textile and apparel industry clusters in Xinjiang was officially announced,marking a new stage in the clustering of Xinjiang's textile and apparel industry.Data shows that the total output value of Xinjiang's cotton and textile and apparel industry chain has exceeded 220 billion yuan.With the nation's largest cotton production,a complete industrial chain system,and strong synergistic effects,Xinjiang has become a leading and highly competitive textile industry hub in China.
文摘The Double Take column looks at a single topic from an African and Chinese perspective.This month,we discuss how to understand the growing emphasis on emotional returns among young people.Emotional value has emerged as a central force shaping youth decision-making across work,consumption,relationships and lifestyle choices.Unlike traditional economic rationality that prioritises income and material security,emotional value focuses on how choices make individuals feel and how they align with personal meaning.This shift is particularly evident in rapidly transforming societies such as China and Ghana,where economic restructuring,globalisation and social change have reshaped pathways to adulthood.
文摘Ming-style furniture represents the pinnacle of Chinese traditional furniture,with the four-head official’s cap chair standing out as a representative category due to its classic form and cultural connotations.This paper takes a specific rosewood four-head official’s cap chair inscribed by Wang Shixiang as the research subject,employing a tripartite approach of form analysis,material examination,and inscription interpretation.The chair strictly adheres to the classic form of Ming-style four-head official’s cap chairs,embodying the Ming Dynasty design philosophy of“the unity of function and aesthetics”.The scarcity and unique grain pattern of the golden-flecked rosewood(Zitan)endow it with the status of“gold among woods”.Wang Shixiang’s inscription binds the furniture to the cultural essence of“the charm of the Ming Dynasty”,transforming it into“heritable cultural heritage”.This paper provides a new perspective for the case study of Ming-style furniture and offers theoretical reference for the contemporary inheritance of traditional craftsmanship.
基金National Social Science Fund project“Research on the Narrative of the Sense of Community for the Chinese Nation in Southwest Nuo Opera”(24XMZ063).
文摘The Nuo mask is the core visual vehicle within China’s Nuo culture and constitutes a complex symbolic system through facial features(icons),patterns(indexes),and colors(symbols).Within the context of intangible cultural heritage(ICH)preservation,its value lies in the continuation and revitalization of its dynamic symbolic functions.Grounded in semiotic theory,this paper elaborates on three core dimensions of symbolic value manifested by Nuo masks in ICH preservation:a ritual symbol for living transmission,a symbol of identity for collective memory,and an aesthetic symbol as a source of creativity.
基金Supported by Zhejiang Provincial Natural Science Foundation of China(LY22F020025)the National Natural Science Foundation of China(62072126)。
文摘The Transformer has achieved great success in the field of medical image segmentation,but its quadratic computational complexity limits its application in dense medical image prediction.Recently,the receptance weighted key value(RWKV)architecture has garnered widespread attention due to its linear computational complexity and its capability of parallel computation during training.Despite the RWKV model's proficiency in addressing long-range modeling tasks with linear computational complexity,most current RWKV-based approaches employ static scanning patterns.These patterns may inadvertently incorporate biased prior knowledge into the model's predictions.To address this challenge,we propose a multi-head scan strategy combined with padding methods to effectively simulate spatial continuity in 2D images.Within the Feature Aggregation Attention(FAA)module,asymmetric convolutions are designed to aggregate 1D sequence features along a single dimension,thereby expanding effective receptive fields while preserving structural sparsity.Additionally,panoramic token shift(P-Shift)effectively models local dependency relationships by moving tokens from a wide receptive field.Extensive experiments conducted on the ISIC17/18 and ACDC datasets demonstrate that our method exhibits superior performance in dense medical image prediction tasks.
基金supported by the National Natural Science Foundation of China(No.4230130142401322)+2 种基金the Scientific Research Foundation of Hunan Provincial Education Department,China(No.22A0159No.22B0191)the Fund Project of Key Laboratory of Rule of Law Research of Ministry of Natural Resources(CUGFZ-2204)。
文摘Numerous economically underdeveloped and ecologically fragile areas in southern China's mountainous regions face increasing challenges in achieving sustainable development. A comparative analysis of ecosystem service responses to land use scenarios, incorporating adaptive valuation coefficients, can reveal actionable pathways to reconcile sustainable development and ecological conservation in mountainous regions. In this study, the ecosystem service value(ESV) dynamics in the Hunan–Jiangxi Border Region(HJBR), which is a representative old revolutionary base with a relatively undeveloped economy, were investigated by integrating historical land use data analysis from 2000 to 2020 and adopting patch-generating land use simulation(PLUS) modelling. Three policy-responsive scenarios, namely, natural growth(NGS), farmland protection(FPS), and ecological protection(EPS), were systematically developed to project ESV variations for 2030 and 2040. Our analysis revealed that from 2000 to 2020, urban sprawl and water body expansion occurred at the expense of forestland, cultivated land, and grassland, yet yield-driven productivity improvements increased the ESV by 227.30%(equivalent to ¥250.0 billion). By 2040, the NGS achieves the greatest ESV increase(¥189.895 billion) while fully accommodating urban land demand;the FPS yields the smallest ESV increase(¥148.169 billion), with the EPS occupying an intermediate position(¥182.207 billion). Climate regulation and hydrological services dominate ecological functions, collectively exceeding 49% across all the scenarios and periods. By 2040, most service functions exhibit growth trends except for a 0.30% water supply decline under the FPS, whereas the EPS demonstrates balanced development through multidimensional service enhancements. These findings underscore the necessity of integrating ecological safeguards into land use planning frameworks to ensure sustainable regional development.
基金supported by the Key Program of the National Natural Science Foundation of China(Grant No.41931293)the National Natural Science Foundation of China(Grant No.42271275).
文摘The rapid population and land urbanization not only promoted economic development but also affected the ecosystem service value(ESV).In the context of new-type urbanization and green development,it’s essential to investigate the impacts of urbanization on ESV in China.However,a comprehensive and dynamic framework to reveal the relationship between ESV and urbanization processes is lacking.This study adopted multi-source datasets to portray China’s urbanization process by integrating population,land,and economic urbanization,eval-uated the ESV changes of 10 categories by gross ecosystem product(GEP)methods,and explored ESV changes within different urbanization scales and speeds.The results showed rapid urbanization in the population,land,and economic dimensions in China,with a faster process of economic urbanization.The ESV also exhibited an increasing trend,with higher levels in the southeastern coastal regions and lower levels in the northwestern regions.Urbanization had positive impacts on ESV across various research units,but the ESV exhibited heteroge-neous changes across different urbanization scales,speeds,and their interactive effects.The response of ESV to dynamic urbanization processes was influenced by socio-economic,ecological,and policy factors;it is essential to combine targeted measures with general ecological product value realization methods in each unit to maximize social-economic-ecological benefits.
文摘BACKGROUND Acute-on-chronic liver failure(ACLF)is a liver disease based on chronic liver disease,which is significantly influenced by clinical treatment regimen and disease status,and despite the existence of multiple prognostic assessment indicators for ACLF,the overall sensitivity and accuracy are relatively low.AIM To investigate the prognostic value of the combined detection of alpha-fetoprotein(AFP),plasma prothrombin activity(PTA),and serum prealbumin(PA)in ACLF.METHODS This retrospective study included 87 patients with ACLF admitted from February 2021 to February 2023 and categorized them into the survival(n=47)and death(n=40)groups according to their clinical outcomes 3 months posttreatment.All the participants underwent AFP,PTA,and PA level measurements upon admission.Baseline data,as well as AFP,PTA,and PA levels,were comparatively analyzed.Pearson correlation coefficients were utilized to analyze the correlations of AFP,PTA,and PA with different survival outcomes in patients with ACLF.Receiver operating characteristic(ROC)curves and areas under the curves were used to evaluate the predictive value of AFP,PTA,and PA for ACLF prognosis.RESULTS AFP,PTA,and PA levels were markedly decreased in the death group than in the survival group(P<0.05).Pearson analysis indicated a positive association of the AFP,PTA,and PA levels with the survival of patients with ACLF(P<0.05).ROC curve analysis determined the sensitivity and specificity of the combined diagnosis at 91.24%and 100.00%,respectively,both of which were notably increased compared to the single-index diagnosis.The ROC of their combined diagnosis was 0.989,significantly surpassing 0.907,0.849,and 0.853 of AFP,PTA,and PA,respectively.No statistically significant variance was determined in the sensitivity and specificity of the combined diagnosis vs the single detection(P>0.05).CONCLUSION The combined detection of AFP,PTA,and PA levels demonstrates favorable diagnostic value for the short-term prognosis of patients with ACLF,featuring high sensitivity and specificity.
