<strong>Purpose:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Radiotherapy is a widely accepted standard of care for early-sta...<strong>Purpose:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Radiotherapy is a widely accepted standard of care for early-stage prostate cancer, and it is believed that the plan quality and treatment outcome are associated with contour accuracy of both the target and organs-at-risk (OAR). The purposes of this study are to 1) assess geometric and dosimetric uncertainties due to inter-observer contour variabilities and 2) evaluate the effectiveness of geometric indicators to predict target dosimetry in prostate radiotherapy. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Twenty prostate patients were selected for this retrospective study. Five experienced clinicians created unique structure sets containing prostate, seminal vesicles, bladder, and rectum for each patient. A fully automated script and knowledge-based planning routine were utilized to create standardized and unbiased plans that could be used to evaluate changes in isodose distributions due to inter-observer variability in structure segmentation. Plans were created on a “gold-standard” structure set, as well as on each of the user-defined structure sets. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Inter-observer variability of contours during structure segmentation was very low for clearly defined organs such as the bladder but increased for organs without well-defined borders (prostate, seminal vesicles, and rectum). For plans generated with the user-defined structure sets, strong/moderate correlations were observed between the geometric indicators for target structure agreement and target coverage for both low-risk and intermediate-risk patient groups, while OAR indicators showed no correlation to final dosimetry. </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Target delineation is crucial in order to maintain adequate dosimetric coverage regardless of the associated inter-observer uncertainties in OAR contours that had a limited impact upon final dosimetry.</span></span>展开更多
The surrogate model serves as an efficient simulation tool during the slope parameter inversion process.However,the creep constitutive model integrated with dynamic damage evolution poses challenges in development of ...The surrogate model serves as an efficient simulation tool during the slope parameter inversion process.However,the creep constitutive model integrated with dynamic damage evolution poses challenges in development of the required surrogate model.In this study,a novel physics knowledge-based surrogate model framework is proposed.In this framework,a Transformer module is employed to capture straindriven softening-hardening physical mechanisms.Positional encoding and self-attention are utilized to transform the constitutive parameters associated with shear strain,which are not directly time-related,into intermediate latent features for physical loss calculation.Next,a multi-layer stacked GRU(gated recurrent unit)network is built to provide input interfaces for time-dependent intermediate latent features,hydraulic boundary conditions,and water-rock interaction degradation equations,with static parameters introduced via external fully-connected layers.Finally,a combined loss function is constructed to facilitate the collaborative training of physical and data loss,introducing time-dependent weight adjustments to focus the surrogate model on accurate deformation predictions during critical phases.Based on the deformation of a reservoir bank landslide triggered by impoundment and subsequent restabilization,an elasto-viscoplastic constitutive model that considers water effect and sliding state dependencies is developed to validate the proposed surrogate model framework.The results indicate that the framework exhibits good performance in capturing physical mechanisms and predicting creep behavior,reducing errors by about 30 times compared to baseline models such as GRU and LSTM(long short-term memory),meeting the precision requirements for parameter inversion.Ablation experiments also confirmed the effectiveness of the framework.This framework can also serve as a reference for constructing other creep surrogate models that involve non-time-related across dimensions.展开更多
Background External knowledge representations play an essential role in knowledge-based visual question and answering to better understand complex scenarios in the open world.Recent entity-relationship embedding appro...Background External knowledge representations play an essential role in knowledge-based visual question and answering to better understand complex scenarios in the open world.Recent entity-relationship embedding approaches are deficient in representing some complex relations,resulting in a lack of topic-related knowledge and redundancy in topic-irrelevant information.Methods To this end,we propose MKEAH:Multimodal Knowledge Extraction and Accumulation on Hyperplanes.To ensure that the lengths of the feature vectors projected onto the hyperplane compare equally and to filter out sufficient topic-irrelevant information,two losses are proposed to learn the triplet representations from the complementary views:range loss and orthogonal loss.To interpret the capability of extracting topic-related knowledge,we present the Topic Similarity(TS)between topic and entity-relations.Results Experimental results demonstrate the effectiveness of hyperplane embedding for knowledge representation in knowledge-based visual question answering.Our model outperformed state-of-the-art methods by 2.12%and 3.24%on two challenging knowledge-request datasets:OK-VQA and KRVQA,respectively.Conclusions The obvious advantages of our model in TS show that using hyperplane embedding to represent multimodal knowledge can improve its ability to extract topic-related knowledge.展开更多
This study examines the methods to plan the development of offshore oilfields over the years,which are used to support the decision-making on the development of offshore oilfields.About 100 papers are analysed and cat...This study examines the methods to plan the development of offshore oilfields over the years,which are used to support the decision-making on the development of offshore oilfields.About 100 papers are analysed and categorised into different groups of main early-stage decisions.The present study stands in contrast to the contributions of the operations research and system engineering review articles,on the one hand,and the petroleum engineering review articles,on the other.This is because it does not focus on one methodological approach,nor does it limit the literature analysis by offshore oilfield characteristics.Consequently,the present analysis may offer valuable insights,for instance,by identifying environmental planning decisions as a recent yet highly significant concern that is currently being imposed on decision-making process.Thus,it is evident that the incorporation of safety criteria within the technical-economic decision-making process for the design of production systems would be a crucial requirement at development phase.展开更多
A machine-learning approach was developed for automated building of knowledgebases for soil resources mapping by using a classification tree to generate knowledge from trainingdata. With this method, building a knowle...A machine-learning approach was developed for automated building of knowledgebases for soil resources mapping by using a classification tree to generate knowledge from trainingdata. With this method, building a knowledge base for automated soil mapping was easier than usingthe conventional knowledge acquisition approach. The knowledge base built by classification tree wasused by the knowledge classifier to perform the soil type classification of Longyou County,Zhejiang Province, China using Landsat TM bi-temporal images and CIS data. To evaluate theperformance of the resultant knowledge bases, the classification results were compared to existingsoil map based on a field survey. The accuracy assessment and analysis of the resultant soil mapssuggested that the knowledge bases built by the machine-learning method was of good quality formapping distribution model of soil classes over the study area.展开更多
Due to the insufficiency of utilizing knowledge to guide the complex optimal searching, existing genetic algorithms fail to effectively solve excavator boom structural optimization problem. To improve the optimization...Due to the insufficiency of utilizing knowledge to guide the complex optimal searching, existing genetic algorithms fail to effectively solve excavator boom structural optimization problem. To improve the optimization efficiency and quality, a new knowledge-based real-coded genetic algorithm is proposed. A dual evolution mechanism combining knowledge evolution with genetic algorithm is established to extract, handle and utilize the shallow and deep implicit constraint knowledge to guide the optimal searching of genetic algorithm circularly. Based on this dual evolution mechanism, knowledge evolution and population evolution can be connected by knowledge influence operators to improve the conflgurability of knowledge and genetic operators. Then, the new knowledge-based selection operator, crossover operator and mutation operator are proposed to integrate the optimal process knowledge and domain culture to guide the excavator boom structural optimization. Eight kinds of testing algorithms, which include different genetic operators, arc taken as examples to solve the structural optimization of a medium-sized excavator boom. By comparing the results of optimization, it is shown that the algorithm including all the new knowledge-based genetic operators can more remarkably improve the evolutionary rate and searching ability than other testing algorithms, which demonstrates the effectiveness of knowledge for guiding optimal searching. The proposed knowledge-based genetic algorithm by combining multi-level knowledge evolution with numerical optimization provides a new effective method for solving the complex engineering optimization problem.展开更多
Knowledge-Based Engineering （KBE） is introduced into the ship structural design in this paper. From the implementation of KBE, the design solutions for both Rules Design Method （RDM） and Interpolation Design Meth...Knowledge-Based Engineering （KBE） is introduced into the ship structural design in this paper. From the implementation of KBE, the design solutions for both Rules Design Method （RDM） and Interpolation Design Method （IDM） are generated. The corresponding Finite Element （FE） models are generated. Topological design of the longitudinal structures is studied where the Gaussian Process （GP） is employed to build the surrogate model for FE analysis. Multi-objective optimization methods inspired by Pareto Front are used to reduce the design tank weight and outer surface area simultaneously. Additionally, an enhanced Level Set Method （LSM） which employs implicit algorithm is applied to the topological design of typical bracket plate which is used extensively in ship structures. Two different sets of boundary conditions are considered. The proposed methods show satisfactory efficiency and accuracy.展开更多
A novel knowledge-based fuzzy neural network （KBFNN） for fault diagnosis is presented. Crude rules were extracted and the corresponding dependent factors and antecedent coverage factors were calculated firstly from ...A novel knowledge-based fuzzy neural network （KBFNN） for fault diagnosis is presented. Crude rules were extracted and the corresponding dependent factors and antecedent coverage factors were calculated firstly from the diagnostic sample based on rough sets theory. Then the number of rules was used to construct partially the structure of a fuzzy neural network and those factors were implemented as initial weights, with fuzzy output parameters being optimized by genetic algorithm. Such fuzzy neural network was called KBFNN. This KBFNN was utilized to identify typical faults of rotating machinery. Diagnostic results show that it has those merits of shorter training time and higher right diagnostic level compared to general fuzzy neural networks.展开更多
Biological raw data are growing exponentially, providing a large amount of information on what life is. It is believed that potential functions and the rules governing protein behaviors can be revealed from analysis o...Biological raw data are growing exponentially, providing a large amount of information on what life is. It is believed that potential functions and the rules governing protein behaviors can be revealed from analysis on known native structures of proteins. Many knowledge-based potentials for proteins have been proposed. Contrary to most existing review articles which mainly describe technical details and applications of various potential models, the main foci for the discussion here are ideas and concepts involving the construction of potentials, including the relation between free energy and energy, the additivity of potentials of mean force and some key issues in potential construction. Sequence analysis is briefly viewed from an energetic viewpoint.展开更多
This paper describes the development of a knowledgebased system (KBS) for determining whether or not, and under what conditions, a bank Ioan officer should grant a business loan to a company. The prototype system deve...This paper describes the development of a knowledgebased system (KBS) for determining whether or not, and under what conditions, a bank Ioan officer should grant a business loan to a company. The prototype system developed focuses on what is bank loans risks management, how to prevent risk by the analysis of the ability of paying back loans. The paper makes the structural analysis involved in the system's decision situation, the structured situation diagram or model, dependency diagram and the document needed by the KBS prototype system thus are developed. Through testing the samples from loan business, the quality for the analysis of the ability of paying back loans can be effectively evaluated by the KBS prototype system.展开更多
The limitations of traditional approaches to selection problems are examined. A problemsolving strategy is presented in which decision-support and knowledge-based techniques play complementary roles. An approach to th...The limitations of traditional approaches to selection problems are examined. A problemsolving strategy is presented in which decision-support and knowledge-based techniques play complementary roles. An approach to the representation of knowledge to support the problem-solving strategy is presented which avoids commitment to a specific programming language or implementation environment. The problem of choosing a home is used to illustrate the representation of knowledge in a specific problem domain. Techniques for implementation of the problem-solving strategy are described. Knowledge elicitation techniques and their implementation in a development shell for application of the problem-solving strategy to any selection problem are also described.展开更多
In the spinning process, some key process parameters( i. e.,raw material index inputs) have very strong relationship with the quality of finished products. The abnormal changes of these process parameters could result...In the spinning process, some key process parameters( i. e.,raw material index inputs) have very strong relationship with the quality of finished products. The abnormal changes of these process parameters could result in various categories of faulty products. In this paper, a hybrid learning-based model was developed for on-line intelligent monitoring and diagnosis of the spinning process. In the proposed model, a knowledge-based artificial neural network( KBANN) was developed for monitoring the spinning process and recognizing faulty quality categories of yarn. In addition,a rough set( RS)-based rule extraction approach named RSRule was developed to discover the causal relationship between textile parameters and yarn quality. These extracted rules were applied in diagnosis of the spinning process, provided guidelines on improving yarn quality,and were used to construct KBANN. Experiments show that the proposed model significantly improve the learning efficiency, and its prediction precision is improved by about 5. 4% compared with the BP neural network model.展开更多
The Financial Crisis in Asia is having a negative impacion the economic development of China, but it also enlightens us. It makes us consider and take measures to avoid such a crisis. I have put forward six measures, ...The Financial Crisis in Asia is having a negative impacion the economic development of China, but it also enlightens us. It makes us consider and take measures to avoid such a crisis. I have put forward six measures, one of which is to promote the transformation of S&T knowledge into productive forces.展开更多
Steps of manipulation is required to complete the m od eling of the connection elements such as bolt, pin and the like in commerce CAD system. It leads to low efficiency, difficulty to assure the relative position, im...Steps of manipulation is required to complete the m od eling of the connection elements such as bolt, pin and the like in commerce CAD system. It leads to low efficiency, difficulty to assure the relative position, impossibility to express rules and knowledge. Based on the inner character analy sis of interpart, detail modification and assembly relation of mechanical connec ting element, the idea, which extends the feature modeling of part to the interp art feature modeling for assembly purpose, is presented, and virtual part based connecting element modeling is proposed. Virtual part is a complement set of lo cal modification of part to be connected. In assembly modeling, base part is mod ified by Boolean operation between base part and virtual part. The modeling and assembly is finished just in one operation, at the same time the rules and knowl edge of the connection elements are encapsulated through virtual part. According to this mechanism, a knowledge-based connecting elements rapid design module i s developed on commerce software package UG with satisfying results.展开更多
Knowledge-based scoring functions have been widely used for protein structure prediction, protein-small molecule, and protein-nucleic acid interactions, in which one critical step is to find an appropriate representat...Knowledge-based scoring functions have been widely used for protein structure prediction, protein-small molecule, and protein-nucleic acid interactions, in which one critical step is to find an appropriate representation of protein structures. A key issue is to determine the minimal protein representations, which is important not only for developing of scoring func- tions but also for understanding the physics of protein folding. Despite significant progresses in simplifying residues into alphabets, few studies have been done to address the optimal number of atom types for proteins. Here, we have investigated the atom typing issue by classifying the 167 heavy atoms of proteins through 11 schemes with 1 to 20 atom types based on their physicochemical and functional environments. For each atom typing scheme, a statistical mechanics-based iterative method was used to extract atomic distance-dependent potentials from protein structures. The atomic distance-dependent pair potentials for different schemes were illustrated by several typical atom pairs with different physicochemical proper- ties. The derived potentials were also evaluated on a high-resolution test set of 148 diverse proteins for native structure recognition. It was found that there was a crossover around the scheme of four atom types in terms of the success rate as a function of the number of atom types, which means that four atom types may be used when investigating the basic folding mechanism of proteins. However, it was revealed by a close examination of typical potentials that 14 atom types were needed to describe the protein interactions at atomic level. The present study will be beneficial for the development of protein related scoring functions and the understanding of folding mechanisms.展开更多
We develop a neuro-knowledge-based expert system (NKBES) frame in this work. The system mainly concerns with decision of gating system and die casting machine based on a neuro-inference engine launched under the MATLA...We develop a neuro-knowledge-based expert system (NKBES) frame in this work. The system mainly concerns with decision of gating system and die casting machine based on a neuro-inference engine launched under the MATLAB software environment. For enhancement of reasoning agility, an error back-propagation neural network was applied. A rapidly convergent adaptive learning rate (ALR) and a momentum-based error back-propagation algorithm was used to conduct neuro-reasoning. The working effect of the system was compared to a conventional expert system that is based on a two-way (forward and backward) chaining inference mechanism. As the reference, the present paper provided the neural networks sum-squared error (S5E) and ALR vs iterative epoch curves of process planning case mentioned above. The study suggests that the neuro-modeling optimization application to die casting process design has good feasibility, and based on that a novel and effective intelligent expert system can be launched at low cost.展开更多
A knowledge-based decision supporting system, used for engineering design is introduced by describing the architecture, function, workflow of the system and its way of implementation. Based upon information composed o...A knowledge-based decision supporting system, used for engineering design is introduced by describing the architecture, function, workflow of the system and its way of implementation. Based upon information composed of knowledge, models, data, cases, methods, etc, the system is designed to use such methods as knowledge-based reasoning, case-based reasoning, and multi-criteria evaluation techniques to provide effective tools to support the decision-making process.展开更多
Ribonucleic acids(RNAs)play a vital role in biology,and knowledge of their three-dimensional(3D)structure is required to understand their biological functions.Recently structural prediction methods have been developed...Ribonucleic acids(RNAs)play a vital role in biology,and knowledge of their three-dimensional(3D)structure is required to understand their biological functions.Recently structural prediction methods have been developed to address this issue,but a series of RNA 3D structures are generally predicted by most existing methods.Therefore,the evaluation of the predicted structures is generally indispensable.Although several methods have been proposed to assess RNA 3D structures,the existing methods are not precise enough.In this work,a new all-atom knowledge-based potential is developed for more accurately evaluating RNA 3D structures.The potential not only includes local and nonlocal interactions but also fully considers the specificity of each RNA by introducing a retraining mechanism.Based on extensive test sets generated from independent methods,the proposed potential correctly distinguished the native state and ranked near-native conformations to effectively select the best.Furthermore,the proposed potential precisely captured RNA structural features such as base-stacking and base-pairing.Comparisons with existing potential methods show that the proposed potential is very reliable and accurate in RNA 3D structure evaluation.展开更多
文摘<strong>Purpose:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Radiotherapy is a widely accepted standard of care for early-stage prostate cancer, and it is believed that the plan quality and treatment outcome are associated with contour accuracy of both the target and organs-at-risk (OAR). The purposes of this study are to 1) assess geometric and dosimetric uncertainties due to inter-observer contour variabilities and 2) evaluate the effectiveness of geometric indicators to predict target dosimetry in prostate radiotherapy. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Twenty prostate patients were selected for this retrospective study. Five experienced clinicians created unique structure sets containing prostate, seminal vesicles, bladder, and rectum for each patient. A fully automated script and knowledge-based planning routine were utilized to create standardized and unbiased plans that could be used to evaluate changes in isodose distributions due to inter-observer variability in structure segmentation. Plans were created on a “gold-standard” structure set, as well as on each of the user-defined structure sets. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Inter-observer variability of contours during structure segmentation was very low for clearly defined organs such as the bladder but increased for organs without well-defined borders (prostate, seminal vesicles, and rectum). For plans generated with the user-defined structure sets, strong/moderate correlations were observed between the geometric indicators for target structure agreement and target coverage for both low-risk and intermediate-risk patient groups, while OAR indicators showed no correlation to final dosimetry. </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Target delineation is crucial in order to maintain adequate dosimetric coverage regardless of the associated inter-observer uncertainties in OAR contours that had a limited impact upon final dosimetry.</span></span>
基金supported by the National Natural Science Foundation of China(Grant No.41961134032).
文摘The surrogate model serves as an efficient simulation tool during the slope parameter inversion process.However,the creep constitutive model integrated with dynamic damage evolution poses challenges in development of the required surrogate model.In this study,a novel physics knowledge-based surrogate model framework is proposed.In this framework,a Transformer module is employed to capture straindriven softening-hardening physical mechanisms.Positional encoding and self-attention are utilized to transform the constitutive parameters associated with shear strain,which are not directly time-related,into intermediate latent features for physical loss calculation.Next,a multi-layer stacked GRU(gated recurrent unit)network is built to provide input interfaces for time-dependent intermediate latent features,hydraulic boundary conditions,and water-rock interaction degradation equations,with static parameters introduced via external fully-connected layers.Finally,a combined loss function is constructed to facilitate the collaborative training of physical and data loss,introducing time-dependent weight adjustments to focus the surrogate model on accurate deformation predictions during critical phases.Based on the deformation of a reservoir bank landslide triggered by impoundment and subsequent restabilization,an elasto-viscoplastic constitutive model that considers water effect and sliding state dependencies is developed to validate the proposed surrogate model framework.The results indicate that the framework exhibits good performance in capturing physical mechanisms and predicting creep behavior,reducing errors by about 30 times compared to baseline models such as GRU and LSTM(long short-term memory),meeting the precision requirements for parameter inversion.Ablation experiments also confirmed the effectiveness of the framework.This framework can also serve as a reference for constructing other creep surrogate models that involve non-time-related across dimensions.
基金Supported by National Nature Science Foudation of China(61976160,61906137,61976158,62076184,62076182)Shanghai Science and Technology Plan Project(21DZ1204800)。
文摘Background External knowledge representations play an essential role in knowledge-based visual question and answering to better understand complex scenarios in the open world.Recent entity-relationship embedding approaches are deficient in representing some complex relations,resulting in a lack of topic-related knowledge and redundancy in topic-irrelevant information.Methods To this end,we propose MKEAH:Multimodal Knowledge Extraction and Accumulation on Hyperplanes.To ensure that the lengths of the feature vectors projected onto the hyperplane compare equally and to filter out sufficient topic-irrelevant information,two losses are proposed to learn the triplet representations from the complementary views:range loss and orthogonal loss.To interpret the capability of extracting topic-related knowledge,we present the Topic Similarity(TS)between topic and entity-relations.Results Experimental results demonstrate the effectiveness of hyperplane embedding for knowledge representation in knowledge-based visual question answering.Our model outperformed state-of-the-art methods by 2.12%and 3.24%on two challenging knowledge-request datasets:OK-VQA and KRVQA,respectively.Conclusions The obvious advantages of our model in TS show that using hyperplane embedding to represent multimodal knowledge can improve its ability to extract topic-related knowledge.
基金the Strategic Research Plan of the Centre for Marine Technology and Ocean Engineering(CENTEC),which is financed by the Portuguese Foundation for Science and Technology(Fundação para a Ciência e a Tecnologia FCT)under contract UIDB/UIDP/00134/2020.
文摘This study examines the methods to plan the development of offshore oilfields over the years,which are used to support the decision-making on the development of offshore oilfields.About 100 papers are analysed and categorised into different groups of main early-stage decisions.The present study stands in contrast to the contributions of the operations research and system engineering review articles,on the one hand,and the petroleum engineering review articles,on the other.This is because it does not focus on one methodological approach,nor does it limit the literature analysis by offshore oilfield characteristics.Consequently,the present analysis may offer valuable insights,for instance,by identifying environmental planning decisions as a recent yet highly significant concern that is currently being imposed on decision-making process.Thus,it is evident that the incorporation of safety criteria within the technical-economic decision-making process for the design of production systems would be a crucial requirement at development phase.
基金Project supported by the National Natural Science Foundation of China(Nos.40101014 and 40001008).
文摘A machine-learning approach was developed for automated building of knowledgebases for soil resources mapping by using a classification tree to generate knowledge from trainingdata. With this method, building a knowledge base for automated soil mapping was easier than usingthe conventional knowledge acquisition approach. The knowledge base built by classification tree wasused by the knowledge classifier to perform the soil type classification of Longyou County,Zhejiang Province, China using Landsat TM bi-temporal images and CIS data. To evaluate theperformance of the resultant knowledge bases, the classification results were compared to existingsoil map based on a field survey. The accuracy assessment and analysis of the resultant soil mapssuggested that the knowledge bases built by the machine-learning method was of good quality formapping distribution model of soil classes over the study area.
基金supported by National Natural Science Foundation of China(Grant No.51175086)
文摘Due to the insufficiency of utilizing knowledge to guide the complex optimal searching, existing genetic algorithms fail to effectively solve excavator boom structural optimization problem. To improve the optimization efficiency and quality, a new knowledge-based real-coded genetic algorithm is proposed. A dual evolution mechanism combining knowledge evolution with genetic algorithm is established to extract, handle and utilize the shallow and deep implicit constraint knowledge to guide the optimal searching of genetic algorithm circularly. Based on this dual evolution mechanism, knowledge evolution and population evolution can be connected by knowledge influence operators to improve the conflgurability of knowledge and genetic operators. Then, the new knowledge-based selection operator, crossover operator and mutation operator are proposed to integrate the optimal process knowledge and domain culture to guide the excavator boom structural optimization. Eight kinds of testing algorithms, which include different genetic operators, arc taken as examples to solve the structural optimization of a medium-sized excavator boom. By comparing the results of optimization, it is shown that the algorithm including all the new knowledge-based genetic operators can more remarkably improve the evolutionary rate and searching ability than other testing algorithms, which demonstrates the effectiveness of knowledge for guiding optimal searching. The proposed knowledge-based genetic algorithm by combining multi-level knowledge evolution with numerical optimization provides a new effective method for solving the complex engineering optimization problem.
基金financially supported by the Project of Ministry of Education and Finance of China(Grant Nos.200512 and 201335)the Project of the State Key Laboratory of Ocean Engineering,Shanghai Jiao Tong University(Grant No.GKZD010053-10)
文摘Knowledge-Based Engineering （KBE） is introduced into the ship structural design in this paper. From the implementation of KBE, the design solutions for both Rules Design Method （RDM） and Interpolation Design Method （IDM） are generated. The corresponding Finite Element （FE） models are generated. Topological design of the longitudinal structures is studied where the Gaussian Process （GP） is employed to build the surrogate model for FE analysis. Multi-objective optimization methods inspired by Pareto Front are used to reduce the design tank weight and outer surface area simultaneously. Additionally, an enhanced Level Set Method （LSM） which employs implicit algorithm is applied to the topological design of typical bracket plate which is used extensively in ship structures. Two different sets of boundary conditions are considered. The proposed methods show satisfactory efficiency and accuracy.
基金Project supported by the National Major Science and Technology Foundation of China during the 10th Five-Year Plan Period(No.2001BA204B05-KHK Z0009)
文摘A novel knowledge-based fuzzy neural network （KBFNN） for fault diagnosis is presented. Crude rules were extracted and the corresponding dependent factors and antecedent coverage factors were calculated firstly from the diagnostic sample based on rough sets theory. Then the number of rules was used to construct partially the structure of a fuzzy neural network and those factors were implemented as initial weights, with fuzzy output parameters being optimized by genetic algorithm. Such fuzzy neural network was called KBFNN. This KBFNN was utilized to identify typical faults of rotating machinery. Diagnostic results show that it has those merits of shorter training time and higher right diagnostic level compared to general fuzzy neural networks.
基金Project supported in part by the National Natural Science Foundation of China(Grant Nos.11175224 and 11121403)
文摘Biological raw data are growing exponentially, providing a large amount of information on what life is. It is believed that potential functions and the rules governing protein behaviors can be revealed from analysis on known native structures of proteins. Many knowledge-based potentials for proteins have been proposed. Contrary to most existing review articles which mainly describe technical details and applications of various potential models, the main foci for the discussion here are ideas and concepts involving the construction of potentials, including the relation between free energy and energy, the additivity of potentials of mean force and some key issues in potential construction. Sequence analysis is briefly viewed from an energetic viewpoint.
基金Supported by the National Science Foundation of China(No.7977086)
文摘This paper describes the development of a knowledgebased system (KBS) for determining whether or not, and under what conditions, a bank Ioan officer should grant a business loan to a company. The prototype system developed focuses on what is bank loans risks management, how to prevent risk by the analysis of the ability of paying back loans. The paper makes the structural analysis involved in the system's decision situation, the structured situation diagram or model, dependency diagram and the document needed by the KBS prototype system thus are developed. Through testing the samples from loan business, the quality for the analysis of the ability of paying back loans can be effectively evaluated by the KBS prototype system.
文摘The limitations of traditional approaches to selection problems are examined. A problemsolving strategy is presented in which decision-support and knowledge-based techniques play complementary roles. An approach to the representation of knowledge to support the problem-solving strategy is presented which avoids commitment to a specific programming language or implementation environment. The problem of choosing a home is used to illustrate the representation of knowledge in a specific problem domain. Techniques for implementation of the problem-solving strategy are described. Knowledge elicitation techniques and their implementation in a development shell for application of the problem-solving strategy to any selection problem are also described.
基金National Natural Science Foundation of China(No.51175077)
文摘In the spinning process, some key process parameters( i. e.,raw material index inputs) have very strong relationship with the quality of finished products. The abnormal changes of these process parameters could result in various categories of faulty products. In this paper, a hybrid learning-based model was developed for on-line intelligent monitoring and diagnosis of the spinning process. In the proposed model, a knowledge-based artificial neural network( KBANN) was developed for monitoring the spinning process and recognizing faulty quality categories of yarn. In addition,a rough set( RS)-based rule extraction approach named RSRule was developed to discover the causal relationship between textile parameters and yarn quality. These extracted rules were applied in diagnosis of the spinning process, provided guidelines on improving yarn quality,and were used to construct KBANN. Experiments show that the proposed model significantly improve the learning efficiency, and its prediction precision is improved by about 5. 4% compared with the BP neural network model.
文摘The Financial Crisis in Asia is having a negative impacion the economic development of China, but it also enlightens us. It makes us consider and take measures to avoid such a crisis. I have put forward six measures, one of which is to promote the transformation of S&T knowledge into productive forces.
文摘Steps of manipulation is required to complete the m od eling of the connection elements such as bolt, pin and the like in commerce CAD system. It leads to low efficiency, difficulty to assure the relative position, impossibility to express rules and knowledge. Based on the inner character analy sis of interpart, detail modification and assembly relation of mechanical connec ting element, the idea, which extends the feature modeling of part to the interp art feature modeling for assembly purpose, is presented, and virtual part based connecting element modeling is proposed. Virtual part is a complement set of lo cal modification of part to be connected. In assembly modeling, base part is mod ified by Boolean operation between base part and virtual part. The modeling and assembly is finished just in one operation, at the same time the rules and knowl edge of the connection elements are encapsulated through virtual part. According to this mechanism, a knowledge-based connecting elements rapid design module i s developed on commerce software package UG with satisfying results.
基金Project supported by the National Natural Science Foundation of China(Grant No.31670724)the National Key Research and Development Program of China(Grant Nos.2016YFC1305800 and 2016YFC1305805)the Startup Grant of Huazhong University of Science and Technology,China
文摘Knowledge-based scoring functions have been widely used for protein structure prediction, protein-small molecule, and protein-nucleic acid interactions, in which one critical step is to find an appropriate representation of protein structures. A key issue is to determine the minimal protein representations, which is important not only for developing of scoring func- tions but also for understanding the physics of protein folding. Despite significant progresses in simplifying residues into alphabets, few studies have been done to address the optimal number of atom types for proteins. Here, we have investigated the atom typing issue by classifying the 167 heavy atoms of proteins through 11 schemes with 1 to 20 atom types based on their physicochemical and functional environments. For each atom typing scheme, a statistical mechanics-based iterative method was used to extract atomic distance-dependent potentials from protein structures. The atomic distance-dependent pair potentials for different schemes were illustrated by several typical atom pairs with different physicochemical proper- ties. The derived potentials were also evaluated on a high-resolution test set of 148 diverse proteins for native structure recognition. It was found that there was a crossover around the scheme of four atom types in terms of the success rate as a function of the number of atom types, which means that four atom types may be used when investigating the basic folding mechanism of proteins. However, it was revealed by a close examination of typical potentials that 14 atom types were needed to describe the protein interactions at atomic level. The present study will be beneficial for the development of protein related scoring functions and the understanding of folding mechanisms.
文摘We develop a neuro-knowledge-based expert system (NKBES) frame in this work. The system mainly concerns with decision of gating system and die casting machine based on a neuro-inference engine launched under the MATLAB software environment. For enhancement of reasoning agility, an error back-propagation neural network was applied. A rapidly convergent adaptive learning rate (ALR) and a momentum-based error back-propagation algorithm was used to conduct neuro-reasoning. The working effect of the system was compared to a conventional expert system that is based on a two-way (forward and backward) chaining inference mechanism. As the reference, the present paper provided the neural networks sum-squared error (S5E) and ALR vs iterative epoch curves of process planning case mentioned above. The study suggests that the neuro-modeling optimization application to die casting process design has good feasibility, and based on that a novel and effective intelligent expert system can be launched at low cost.
文摘A knowledge-based decision supporting system, used for engineering design is introduced by describing the architecture, function, workflow of the system and its way of implementation. Based upon information composed of knowledge, models, data, cases, methods, etc, the system is designed to use such methods as knowledge-based reasoning, case-based reasoning, and multi-criteria evaluation techniques to provide effective tools to support the decision-making process.
基金Project supported by the National Science Foundation of China(Grants Nos.11605125,11105054,11274124,and 11401448)
文摘Ribonucleic acids(RNAs)play a vital role in biology,and knowledge of their three-dimensional(3D)structure is required to understand their biological functions.Recently structural prediction methods have been developed to address this issue,but a series of RNA 3D structures are generally predicted by most existing methods.Therefore,the evaluation of the predicted structures is generally indispensable.Although several methods have been proposed to assess RNA 3D structures,the existing methods are not precise enough.In this work,a new all-atom knowledge-based potential is developed for more accurately evaluating RNA 3D structures.The potential not only includes local and nonlocal interactions but also fully considers the specificity of each RNA by introducing a retraining mechanism.Based on extensive test sets generated from independent methods,the proposed potential correctly distinguished the native state and ranked near-native conformations to effectively select the best.Furthermore,the proposed potential precisely captured RNA structural features such as base-stacking and base-pairing.Comparisons with existing potential methods show that the proposed potential is very reliable and accurate in RNA 3D structure evaluation.
