With the widespread use of social media,the propagation of health-related rumors has become a significant public health threat.Existing methods for detecting health rumors predominantly rely on external knowledge or p...With the widespread use of social media,the propagation of health-related rumors has become a significant public health threat.Existing methods for detecting health rumors predominantly rely on external knowledge or propagation structures,with only a few recent approaches attempting causal inference;however,these have not yet effectively integrated causal discovery with domain-specific knowledge graphs for detecting health rumors.In this study,we found that the combined use of causal discovery and domain-specific knowledge graphs can effectively identify implicit pseudo-causal logic embedded within texts,holding significant potential for health rumor detection.To this end,we propose CKDG—a dual-graph fusion framework based on causal logic and medical knowledge graphs.CKDG constructs a weighted causal graph to capture the implicit causal relationships in the text and introduces a medical knowledge graph to verify semantic consistency,thereby enhancing the ability to identify the misuse of professional terminology and pseudoscientific claims.In experiments conducted on a dataset comprising 8430 health rumors,CKDG achieved an accuracy of 91.28%and an F1 score of 90.38%,representing improvements of 5.11%and 3.29%over the best baseline,respectively.Our results indicate that the integrated use of causal discovery and domainspecific knowledge graphs offers significant advantages for health rumor detection systems.This method not only improves detection performance but also enhances the transparency and credibility of model decisions by tracing causal chains and sources of knowledge conflicts.We anticipate that this work will provide key technological support for the development of trustworthy health-information filtering systems,thereby improving the reliability of public health information on social media.展开更多
Multi-modal knowledge graph completion(MMKGC)aims to complete missing entities or relations in multi-modal knowledge graphs,thereby discovering more previously unknown triples.Due to the continuous growth of data and ...Multi-modal knowledge graph completion(MMKGC)aims to complete missing entities or relations in multi-modal knowledge graphs,thereby discovering more previously unknown triples.Due to the continuous growth of data and knowledge and the limitations of data sources,the visual knowledge within the knowledge graphs is generally of low quality,and some entities suffer from the issue of missing visual modality.Nevertheless,previous studies of MMKGC have primarily focused on how to facilitate modality interaction and fusion while neglecting the problems of low modality quality and modality missing.In this case,mainstream MMKGC models only use pre-trained visual encoders to extract features and transfer the semantic information to the joint embeddings through modal fusion,which inevitably suffers from problems such as error propagation and increased uncertainty.To address these problems,we propose a Multi-modal knowledge graph Completion model based on Super-resolution and Detailed Description Generation(MMCSD).Specifically,we leverage a pre-trained residual network to enhance the resolution and improve the quality of the visual modality.Moreover,we design multi-level visual semantic extraction and entity description generation,thereby further extracting entity semantics from structural triples and visual images.Meanwhile,we train a variational multi-modal auto-encoder and utilize a pre-trained multi-modal language model to complement the missing visual features.We conducted experiments on FB15K-237 and DB13K,and the results showed that MMCSD can effectively perform MMKGC and achieve state-of-the-art performance.展开更多
Deep-time Earth research plays a pivotal role in deciphering the rates,patterns,and mechanisms of Earth's evolutionary processes throughout geological history,providing essential scientific foundations for climate...Deep-time Earth research plays a pivotal role in deciphering the rates,patterns,and mechanisms of Earth's evolutionary processes throughout geological history,providing essential scientific foundations for climate prediction,natural resource exploration,and sustainable planetary stewardship.To advance Deep-time Earth research in the era of big data and artificial intelligence,the International Union of Geological Sciences initiated the“Deeptime Digital Earth International Big Science Program”(DDE)in 2019.At the core of this ambitious program lies the development of geoscience knowledge graphs,serving as a transformative knowledge infrastructure that enables the integration,sharing,mining,and analysis of heterogeneous geoscience big data.The DDE knowledge graph initiative has made significant strides in three critical dimensions:(1)establishing a unified knowledge structure across geoscience disciplines that ensures consistent representation of geological entities and their interrelationships through standardized ontologies and semantic frameworks;(2)developing a robust and scalable software infrastructure capable of supporting both expert-driven and machine-assisted knowledge engineering for large-scale graph construction and management;(3)implementing a comprehensive three-tiered architecture encompassing basic,discipline-specific,and application-oriented knowledge graphs,spanning approximately 20 geoscience disciplines.Through its open knowledge framework and international collaborative network,this initiative has fostered multinational research collaborations,establishing a robust foundation for next-generation geoscience research while propelling the discipline toward FAIR(Findable,Accessible,Interoperable,Reusable)data practices in deep-time Earth systems research.展开更多
Accurate prediction of drug-target interactions(DTIs)plays a pivotal role in drug discovery,facilitating optimization of lead compounds,drug repurposing and elucidation of drug side effects.However,traditional DTI pre...Accurate prediction of drug-target interactions(DTIs)plays a pivotal role in drug discovery,facilitating optimization of lead compounds,drug repurposing and elucidation of drug side effects.However,traditional DTI prediction methods are often limited by incomplete biological data and insufficient representation of protein features.In this study,we proposed KG-CNNDTI,a novel knowledge graph-enhanced framework for DTI prediction,which integrates heterogeneous biological information to improve model generalizability and predictive performance.The proposed model utilized protein embeddings derived from a biomedical knowledge graph via the Node2Vec algorithm,which were further enriched with contextualized sequence representations obtained from ProteinBERT.For compound representation,multiple molecular fingerprint schemes alongside the Uni-Mol pre-trained model were evaluated.The fused representations served as inputs to both classical machine learning models and a convolutional neural network-based predictor.Experimental evaluations across benchmark datasets demonstrated that KG-CNNDTI achieved superior performance compared to state-of-the-art methods,particularly in terms of Precision,Recall,F1-Score and area under the precision-recall curve(AUPR).Ablation analysis highlighted the substantial contribution of knowledge graph-derived features.Moreover,KG-CNNDTI was employed for virtual screening of natural products against Alzheimer's disease,resulting in 40 candidate compounds.5 were supported by literature evidence,among which 3 were further validated in vitro assays.展开更多
In the international shipping industry, digital intelligence transformation has become essential, with both governments and enterprises actively working to integrate diverse datasets. The domain of maritime and shippi...In the international shipping industry, digital intelligence transformation has become essential, with both governments and enterprises actively working to integrate diverse datasets. The domain of maritime and shipping is characterized by a vast array of document types, filled with complex, large-scale, and often chaotic knowledge and relationships. Effectively managing these documents is crucial for developing a Large Language Model (LLM) in the maritime domain, enabling practitioners to access and leverage valuable information. A Knowledge Graph (KG) offers a state-of-the-art solution for enhancing knowledge retrieval, providing more accurate responses and enabling context-aware reasoning. This paper presents a framework for utilizing maritime and shipping documents to construct a knowledge graph using GraphRAG, a hybrid tool combining graph-based retrieval and generation capabilities. The extraction of entities and relationships from these documents and the KG construction process are detailed. Furthermore, the KG is integrated with an LLM to develop a Q&A system, demonstrating that the system significantly improves answer accuracy compared to traditional LLMs. Additionally, the KG construction process is up to 50% faster than conventional LLM-based approaches, underscoring the efficiency of our method. This study provides a promising approach to digital intelligence in shipping, advancing knowledge accessibility and decision-making.展开更多
With the continuous advancement of information technology,corpora and knowledge graphs(KGs)have become indispensable tools in modern language learning.This study explores how the integration of corpora and KGs in inte...With the continuous advancement of information technology,corpora and knowledge graphs(KGs)have become indispensable tools in modern language learning.This study explores how the integration of corpora and KGs in integrated English teaching can enhance students’abilities in vocabulary acquisition,grammar understanding,and discourse analysis.Through a comprehensive literature review,it elaborates on the theoretical foundations and practical values of these two technological tools in English instruction.The study designs a teaching model based on corpora and KGs and analyzes its specific applications in vocabulary,grammar,and discourse teaching within the Integrated English course.Additionally,the article discusses the challenges that may arise during implementation and proposes corresponding solutions.Finally,it envisions future research directions and application prospects.展开更多
Drug repurposing offers a promising alternative to traditional drug development and significantly re-duces costs and timelines by identifying new therapeutic uses for existing drugs.However,the current approaches ofte...Drug repurposing offers a promising alternative to traditional drug development and significantly re-duces costs and timelines by identifying new therapeutic uses for existing drugs.However,the current approaches often rely on limited data sources and simplistic hypotheses,which restrict their ability to capture the multi-faceted nature of biological systems.This study introduces adaptive multi-view learning(AMVL),a novel methodology that integrates chemical-induced transcriptional profiles(CTPs),knowledge graph(KG)embeddings,and large language model(LLM)representations,to enhance drug repurposing predictions.AMVL incorporates an innovative similarity matrix expansion strategy and leverages multi-view learning(MVL),matrix factorization,and ensemble optimization techniques to integrate heterogeneous multi-source data.Comprehensive evaluations on benchmark datasets(Fdata-set,Cdataset,and Ydataset)and the large-scale iDrug dataset demonstrate that AMVL outperforms state-of-the-art(SOTA)methods,achieving superior accuracy in predicting drug-disease associations across multiple metrics.Literature-based validation further confirmed the model's predictive capabilities,with seven out of the top ten predictions corroborated by post-2011 evidence.To promote transparency and reproducibility,all data and codes used in this study were open-sourced,providing resources for pro-cessing CTPs,KG,and LLM-based similarity calculations,along with the complete AMVL algorithm and benchmarking procedures.By unifying diverse data modalities,AMVL offers a robust and scalable so-lution for accelerating drug discovery,fostering advancements in translational medicine and integrating multi-omics data.We aim to inspire further innovations in multi-source data integration and support the development of more precise and efficient strategies for advancing drug discovery and translational medicine.展开更多
Knowledge graphs (KGs) offer a structured, machine-readable format for organizing complex information. In heterogeneous catalysis, where data on catalytic materials, reaction conditions, mechanisms, and synthesis rout...Knowledge graphs (KGs) offer a structured, machine-readable format for organizing complex information. In heterogeneous catalysis, where data on catalytic materials, reaction conditions, mechanisms, and synthesis routes are dispersed across diverse sources, KGs provide a semantic framework that supports data integration under the FAIR (Findable, Accessible, Interoperable, and Reusable) principles. This review aims to survey recent developments in catalysis KGs, describe the main techniques for graph construction, and highlight how artificial intelligence, particularly large language models (LLMs), enhances graph generation and query. We conducted a systematic analysis of the literature, focusing on ontology-guided text mining pipelines, graph population methods, and maintenance strategies. Our review identifies key trends: ontology-based approaches enable the automated extraction of domain knowledge, LLM-driven retrieval-augmented generation supports natural-language queries, and scalable graph architectures range from a few thousand to over a million triples. We discuss state-of-the-art applications, such as catalyst recommendation systems and reaction mechanism discovery tools, and examine the major challenges, including data heterogeneity, ontology alignment, and long-term graph curation. We conclude that KGs, when combined with AI methods, hold significant promise for accelerating catalyst discovery and knowledge management, but progress depends on establishing community standards for ontology development and maintenance. This review provides a roadmap for researchers seeking to leverage KGs to advance heterogeneous catalysis research.展开更多
The article is based on language model,through the cue word engineering and agent thinking method,automatic knowledge extraction,with China accounting standards support to complete the corresponding knowledge map cons...The article is based on language model,through the cue word engineering and agent thinking method,automatic knowledge extraction,with China accounting standards support to complete the corresponding knowledge map construction.Through the way of extracting the accounting entities and their connections in the pattern layer,the data layer is provided for the fine-tuning and optimization of the large model.Studies found that,through the reasonable application of language model,knowledge can be realized in massive financial data neural five effective extracted tuples,and complete accounting knowledge map construction.展开更多
To address the underutilization of Chinese research materials in nonferrous metals,a method for constructing a domain of nonferrous metals knowledge graph(DNMKG)was established.Starting from a domain thesaurus,entitie...To address the underutilization of Chinese research materials in nonferrous metals,a method for constructing a domain of nonferrous metals knowledge graph(DNMKG)was established.Starting from a domain thesaurus,entities and relationships were mapped as resource description framework(RDF)triples to form the graph’s framework.Properties and related entities were extracted from open knowledge bases,enriching the graph.A large-scale,multi-source heterogeneous corpus of over 1×10^(9) words was compiled from recent literature to further expand DNMKG.Using the knowledge graph as prior knowledge,natural language processing techniques were applied to the corpus,generating word vectors.A novel entity evaluation algorithm was used to identify and extract real domain entities,which were added to DNMKG.A prototype system was developed to visualize the knowledge graph and support human−computer interaction.Results demonstrate that DNMKG can enhance knowledge discovery and improve research efficiency in the nonferrous metals field.展开更多
Existing wireless networks are flooded with video data transmissions,and the demand for high-speed and low-latency video services continues to surge.This has brought with it challenges to networks in the form of conge...Existing wireless networks are flooded with video data transmissions,and the demand for high-speed and low-latency video services continues to surge.This has brought with it challenges to networks in the form of congestion as well as the need for more resources and more dedicated caching schemes.Recently,Multi-access Edge Computing(MEC)-enabled heterogeneous networks,which leverage edge caches for proximity delivery,have emerged as a promising solution to all of these problems.Designing an effective edge caching scheme is critical to its success,however,in the face of limited resources.We propose a novel Knowledge Graph(KG)-based Dueling Deep Q-Network(KG-DDQN)for cooperative caching in MEC-enabled heterogeneous networks.The KGDDQN scheme leverages a KG to uncover video relations,providing valuable insights into user preferences for the caching scheme.Specifically,the KG guides the selection of related videos as caching candidates(i.e.,actions in the DDQN),thus providing a rich reference for implementing a personalized caching scheme while also improving the decision efficiency of the DDQN.Extensive simulation results validate the convergence effectiveness of the KG-DDQN,and it also outperforms baselines regarding cache hit rate and service delay.展开更多
Geologic time is an essential dimension in geological research,acting as a pivotal attribute that integrates data across various subdisciplines.The Geologic Time Scale(GTS)provides a formal framework for interpreting ...Geologic time is an essential dimension in geological research,acting as a pivotal attribute that integrates data across various subdisciplines.The Geologic Time Scale(GTS)provides a formal framework for interpreting and communicating geologic time within the field of geological studies,such as macro-geological evolution and regional geologic surveys.展开更多
Objectives:Chemotherapy-induced nausea and vomiting(CINV)is a common adverse effect among breast cancer patients,significantly affecting quality of life.Existing evidence on the prevention,assessment,and management of...Objectives:Chemotherapy-induced nausea and vomiting(CINV)is a common adverse effect among breast cancer patients,significantly affecting quality of life.Existing evidence on the prevention,assessment,and management of this condition is fragmented and inconsistent.This study constructed a CINV knowledge graph using a large language model(LLM)to integrate nursing and medical evidence,thereby supporting systematic clinical decision-making.Methods:A top-down approach was adopted.1)Knowledge base preparation:Nine databases and eight guideline repositories were searched up to October 2024 to include guidelines,evidence summaries,expert consensuses,and systematic reviews screened by two researchers.2)Schema design:Referring to the Unified Medical Language System,Systematized Nomenclature of Medicine-Clinical Terms,and the Nursing Intervention Classification,entity and relation types were defined to build the ontology schema.3)LLM-based extraction and integration:Using the Qwen model under the CRISPE framework,named entity recognition,relation extraction,disambiguation,and fusion were conducted to generate triples and visualize them in Neo4j.Four expert rounds ensured semantic and logical consistency.Model performance was evaluated using precision,recall,F1-score,and 95%confidence interval(95%CI)in Python 3.11.Result:A total of 47 studies were included(18 guidelines,two expert consensuses,two evidence summaries,and 25 systematic reviews).The Qwen model extracted 273 entities and 289 relations;after expert validation,238 entities and 242 relations were retained,forming 244 triples.The ontology comprised nine entity types and eight relation types.The F1-scores for named entity recognition and relation extraction were 82.97(95%CI:0.820,0.839)and 85.54(95%CI:0.844,0.867),respectively.The average node degree was 2.03,with no isolated nodes.Conclusion:The LLM-based CINV knowledge graph achieved structured integration of nursing and medical evidence,offering a novel,data-driven tool to support clinical nursing decision-making and advance intelligent healthcare.展开更多
As a new data management paradigm,knowledge graphs can integrate multiple data sources and achieve quick responses,reasoning and better predictions in drug discovery.Characterized by powerful contagion and a high rate...As a new data management paradigm,knowledge graphs can integrate multiple data sources and achieve quick responses,reasoning and better predictions in drug discovery.Characterized by powerful contagion and a high rate of morbidity and mortality,porcine reproductive and respiratory syndrome(PRRS)is a common infectious disease in the global swine industry that causes economically great losses.Traditional Chinese medicine(TCM)has advantages in low adverse effects and a relatively affordable cost of application,and TCM is therefore conceived as a possibility to treat PRRS under the current circumstance that there is a lack of safe and effective approaches.Here,we constructed a knowledge graph containing common biomedical data from humans and Sus Scrofa as well as information from thousands of TCMs.Subsequently,we validated the effectiveness of the Sus Scrofa knowledge graph by the t-SNE algorithm and selected the optimal model(i.e.,transR)from six typical models,namely,transE,transR,DistMult,ComplEx,RESCAL and RotatE,according to five indicators,namely,MRR,MR,HITS@1,HITS@3 and HITS@10.Based on embedding vectors trained by the optimal model,anti-PRRSV TCMs were predicted by two paths,namely,VHC-Herb and VHPC-Herb,and potential anti-PRRSVTCMs were identified by retrieving the HERB database according to the phar-macological properties corresponding to symptoms of PRRS.Ultimately,Dan Shen's(Salvia miltiorrhiza Bunge)capacity to resist PRRSV infection was validated by a cell experiment in which the inhibition rate of PRRSV exceeded90%when the concentrations of Dan Shen extract were 0.004,0.008,0.016 and 0.032 mg/mL.In summary,this is the first report on the Sus Scrofa knowledge graph including TCM information,and our study reflects the important application values of deep learning on graphs in the swine industry as well as providing accessible TCM resources for PRRS.展开更多
In recent years,various efforts have been devoted to advancing university education through artificial intelligence(AI).To this end,this paper introduces KCUBE,a novel framework centered on knowledge graphs(KGs)design...In recent years,various efforts have been devoted to advancing university education through artificial intelligence(AI).To this end,this paper introduces KCUBE,a novel framework centered on knowledge graphs(KGs)designed to enhance student advising and career planning in university courses.Owing to KCUBE,we can improve university education in the AI era by leveraging the expressiveness,operability,and interpretability of KGs.We detail a bottom-up approach for KG construction,empowering professors to develop subject-specific KGs,augmented by tools like ChatGPT,which has demonstrated promising accuracy and coverage.Based on KGs,KCUBE supports KG reasoning for applications such as automated teaching plan generation with dynamic editing capabilities.Furthermore,KCUBE offers advanced KG manipulation through 2D and 3D visualization platforms,such as virtual reality(VR)for immersive exploration of academic subjects and potential career paths.A comparative study on collaborative learning highlights the benefits of VR and KG-enhanced environments in promoting student engagement,participation,and collaborative decision-making.展开更多
Geographic Information System(GIS)layers contain both spatial precision and domain knowledge,making them valuable for mineral prospectivity analysis.This study proposes a task-oriented methodology to struct con-a mine...Geographic Information System(GIS)layers contain both spatial precision and domain knowledge,making them valuable for mineral prospectivity analysis.This study proposes a task-oriented methodology to struct con-a mineral prospecting knowledge graph directly from GIS maps.The framework integrates ontology construction,spatiotemporal semantic embedding,and triple confidence evaluation.Ontologies are built from GIS layers through terminology extraction and alignment with existing standards,while spatial and temporal semantics are encoded using GeoSPARQL and the Geological Time Ontology.Graph Convolutional Networks(GCN)combined with the TransE embedding model are then applied to assess triple plausibility.A case study in the Eastern Tianshan region of Xinjiang verifies the effectiveness of the proposed method through semantic evaluation and graph-theoretic analysis.Guided by GIS,ontology construction significantly enhances the semantic fidelity and structural robustness of the prospecting knowledge graph,providing relatively reliable support for subsequent reasoning and predictive studies.展开更多
Knowledge graphs convey precise semantic information that can be effectively interpreted by neural networks,and generating descriptive text based on these graphs places significant emphasis on content consistency.Howe...Knowledge graphs convey precise semantic information that can be effectively interpreted by neural networks,and generating descriptive text based on these graphs places significant emphasis on content consistency.However,knowledge graphs are inadequate for providing additional linguistic features such as paragraph structure and expressive modes,making it challenging to ensure content coherence in generating text that spans multiple sentences.This lack of coherence can further compromise the overall consistency of the content within a paragraph.In this work,we present the generation of scientific abstracts by leveraging knowledge graphs,with a focus on enhancing both content consistency and coherence.In particular,we construct the ACL Abstract Graph Dataset(ACL-AGD)which pairs knowledge graphs with text,incorporating sentence labels to guide text structure and diverse expressions.We then implement a Siamese network to complement and concretize the entities and relations based on paragraph structure by accomplishing two tasks:graph-to-text generation and entity alignment.Extensive experiments demonstrate that the logical paragraphs generated by our method exhibit entities with a uniform position distribution and appropriate frequency.In terms of content,our method accurately represents the information encoded in the knowledge graph,prevents the generation of irrelevant content,and achieves coherent and non-redundant adjacent sentences,even with a shared knowledge graph.展开更多
In the context of the“Two New”initiatives,high school mathematics instruction still grapples with three interlocking problems:knowledge fragmentation,limited cultivation of higher-order thinking,and weak alignment a...In the context of the“Two New”initiatives,high school mathematics instruction still grapples with three interlocking problems:knowledge fragmentation,limited cultivation of higher-order thinking,and weak alignment among teaching,learning,and assessment.To counter these challenges,we propose an Inquiry-Construction Double-Helix model that uses a domain-specific knowledge graph as its cognitive spine.The model interweaves two mutually reinforcing strands-student-driven inquiry and systematic knowledge construction-into a double-helix trajectory analogous to DNA replication.The Inquiry Strand is launched by authentic,situation-based tasks that shepherd students through the complete cycle:question→hypothesis→verification→reflection.The Construction Strand simultaneously externalizes,restructures,and internalizes core disciplinary concepts via visual,hierarchical knowledge graphs.Within the flow of a lesson,the two strands alternately dominate and scaffold each other,securing the co-development of conceptual understanding,procedural fluency,and mathematical literacy.Empirical evidence demonstrates that this model significantly enhances students’systematic knowledge integration,problem-solving transfer ability,and core mathematical competencies,offering a replicable and operable teaching paradigm and practical pathway for deepening high school mathematics classroom reform.展开更多
After the design of aerospace products is completed,a manufacturability assessment needs to be conducted based on 3D model's features in terms of modeling quality and process design,otherwise the cost of design ch...After the design of aerospace products is completed,a manufacturability assessment needs to be conducted based on 3D model's features in terms of modeling quality and process design,otherwise the cost of design changes will increase.Due to the poor structure and low reusability of product manufacturing feature information and assessment knowledge in the current aerospace product manufacturability assessment process,it is difficult to realize automated manufacturability assessment.To address these issues,a domain ontology model is established for aerospace product manufacturability assessment in this paper.On this basis,a structured representation method of manufacturability assessment knowledge and a knowledge graph data layer construction method are proposed.Based on the semantic information and association information expressed by the knowledge graph,a rule matching method based on subgraph matching is proposed to improve the precision and recall.Finally,applications and experiments based on the software platform verify the effectiveness of the proposed knowledge graph construction and rule matching method.展开更多
In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with l...In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with large-scale knowledge graphs that contain vast numbers of entities and relations.In particular,resource-intensive embeddings often lead to increased computational costs,and may limit scalability and adaptability in practical environ-ments,such as in low-resource settings or real-world applications.This paper explores an approach to knowledge graph representation learning that leverages small,reserved entities and relation sets for parameter-efficient embedding.We introduce a hierarchical attention network designed to refine and maximize the representational quality of embeddings by selectively focusing on these reserved sets,thereby reducing model complexity.Empirical assessments validate that our model achieves high performance on the benchmark dataset with fewer parameters and smaller embedding dimensions.The ablation studies further highlight the impact and contribution of each component in the proposed hierarchical attention structure.展开更多
基金funded by the Hunan Provincial Natural Science Foundation of China(Grant No.2025JJ70105)the Hunan Provincial College Students’Innovation and Entrepreneurship Training Program(Project No.S202411342056)The article processing charge(APC)was funded by the Project No.2025JJ70105.
文摘With the widespread use of social media,the propagation of health-related rumors has become a significant public health threat.Existing methods for detecting health rumors predominantly rely on external knowledge or propagation structures,with only a few recent approaches attempting causal inference;however,these have not yet effectively integrated causal discovery with domain-specific knowledge graphs for detecting health rumors.In this study,we found that the combined use of causal discovery and domain-specific knowledge graphs can effectively identify implicit pseudo-causal logic embedded within texts,holding significant potential for health rumor detection.To this end,we propose CKDG—a dual-graph fusion framework based on causal logic and medical knowledge graphs.CKDG constructs a weighted causal graph to capture the implicit causal relationships in the text and introduces a medical knowledge graph to verify semantic consistency,thereby enhancing the ability to identify the misuse of professional terminology and pseudoscientific claims.In experiments conducted on a dataset comprising 8430 health rumors,CKDG achieved an accuracy of 91.28%and an F1 score of 90.38%,representing improvements of 5.11%and 3.29%over the best baseline,respectively.Our results indicate that the integrated use of causal discovery and domainspecific knowledge graphs offers significant advantages for health rumor detection systems.This method not only improves detection performance but also enhances the transparency and credibility of model decisions by tracing causal chains and sources of knowledge conflicts.We anticipate that this work will provide key technological support for the development of trustworthy health-information filtering systems,thereby improving the reliability of public health information on social media.
基金funded by Research Project,grant number BHQ090003000X03。
文摘Multi-modal knowledge graph completion(MMKGC)aims to complete missing entities or relations in multi-modal knowledge graphs,thereby discovering more previously unknown triples.Due to the continuous growth of data and knowledge and the limitations of data sources,the visual knowledge within the knowledge graphs is generally of low quality,and some entities suffer from the issue of missing visual modality.Nevertheless,previous studies of MMKGC have primarily focused on how to facilitate modality interaction and fusion while neglecting the problems of low modality quality and modality missing.In this case,mainstream MMKGC models only use pre-trained visual encoders to extract features and transfer the semantic information to the joint embeddings through modal fusion,which inevitably suffers from problems such as error propagation and increased uncertainty.To address these problems,we propose a Multi-modal knowledge graph Completion model based on Super-resolution and Detailed Description Generation(MMCSD).Specifically,we leverage a pre-trained residual network to enhance the resolution and improve the quality of the visual modality.Moreover,we design multi-level visual semantic extraction and entity description generation,thereby further extracting entity semantics from structural triples and visual images.Meanwhile,we train a variational multi-modal auto-encoder and utilize a pre-trained multi-modal language model to complement the missing visual features.We conducted experiments on FB15K-237 and DB13K,and the results showed that MMCSD can effectively perform MMKGC and achieve state-of-the-art performance.
基金Strategic Priority Research Program of the Chinese Academy of Sciences,No.XDB0740000National Key Research and Development Program of China,No.2022YFB3904200,No.2022YFF0711601+1 种基金Key Project of Innovation LREIS,No.PI009National Natural Science Foundation of China,No.42471503。
文摘Deep-time Earth research plays a pivotal role in deciphering the rates,patterns,and mechanisms of Earth's evolutionary processes throughout geological history,providing essential scientific foundations for climate prediction,natural resource exploration,and sustainable planetary stewardship.To advance Deep-time Earth research in the era of big data and artificial intelligence,the International Union of Geological Sciences initiated the“Deeptime Digital Earth International Big Science Program”(DDE)in 2019.At the core of this ambitious program lies the development of geoscience knowledge graphs,serving as a transformative knowledge infrastructure that enables the integration,sharing,mining,and analysis of heterogeneous geoscience big data.The DDE knowledge graph initiative has made significant strides in three critical dimensions:(1)establishing a unified knowledge structure across geoscience disciplines that ensures consistent representation of geological entities and their interrelationships through standardized ontologies and semantic frameworks;(2)developing a robust and scalable software infrastructure capable of supporting both expert-driven and machine-assisted knowledge engineering for large-scale graph construction and management;(3)implementing a comprehensive three-tiered architecture encompassing basic,discipline-specific,and application-oriented knowledge graphs,spanning approximately 20 geoscience disciplines.Through its open knowledge framework and international collaborative network,this initiative has fostered multinational research collaborations,establishing a robust foundation for next-generation geoscience research while propelling the discipline toward FAIR(Findable,Accessible,Interoperable,Reusable)data practices in deep-time Earth systems research.
基金supported by the National Natural Science Foundation of China(Nos.82173746 and U23A20530)Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism(Shanghai Municipal Education Commission)。
文摘Accurate prediction of drug-target interactions(DTIs)plays a pivotal role in drug discovery,facilitating optimization of lead compounds,drug repurposing and elucidation of drug side effects.However,traditional DTI prediction methods are often limited by incomplete biological data and insufficient representation of protein features.In this study,we proposed KG-CNNDTI,a novel knowledge graph-enhanced framework for DTI prediction,which integrates heterogeneous biological information to improve model generalizability and predictive performance.The proposed model utilized protein embeddings derived from a biomedical knowledge graph via the Node2Vec algorithm,which were further enriched with contextualized sequence representations obtained from ProteinBERT.For compound representation,multiple molecular fingerprint schemes alongside the Uni-Mol pre-trained model were evaluated.The fused representations served as inputs to both classical machine learning models and a convolutional neural network-based predictor.Experimental evaluations across benchmark datasets demonstrated that KG-CNNDTI achieved superior performance compared to state-of-the-art methods,particularly in terms of Precision,Recall,F1-Score and area under the precision-recall curve(AUPR).Ablation analysis highlighted the substantial contribution of knowledge graph-derived features.Moreover,KG-CNNDTI was employed for virtual screening of natural products against Alzheimer's disease,resulting in 40 candidate compounds.5 were supported by literature evidence,among which 3 were further validated in vitro assays.
文摘In the international shipping industry, digital intelligence transformation has become essential, with both governments and enterprises actively working to integrate diverse datasets. The domain of maritime and shipping is characterized by a vast array of document types, filled with complex, large-scale, and often chaotic knowledge and relationships. Effectively managing these documents is crucial for developing a Large Language Model (LLM) in the maritime domain, enabling practitioners to access and leverage valuable information. A Knowledge Graph (KG) offers a state-of-the-art solution for enhancing knowledge retrieval, providing more accurate responses and enabling context-aware reasoning. This paper presents a framework for utilizing maritime and shipping documents to construct a knowledge graph using GraphRAG, a hybrid tool combining graph-based retrieval and generation capabilities. The extraction of entities and relationships from these documents and the KG construction process are detailed. Furthermore, the KG is integrated with an LLM to develop a Q&A system, demonstrating that the system significantly improves answer accuracy compared to traditional LLMs. Additionally, the KG construction process is up to 50% faster than conventional LLM-based approaches, underscoring the efficiency of our method. This study provides a promising approach to digital intelligence in shipping, advancing knowledge accessibility and decision-making.
文摘With the continuous advancement of information technology,corpora and knowledge graphs(KGs)have become indispensable tools in modern language learning.This study explores how the integration of corpora and KGs in integrated English teaching can enhance students’abilities in vocabulary acquisition,grammar understanding,and discourse analysis.Through a comprehensive literature review,it elaborates on the theoretical foundations and practical values of these two technological tools in English instruction.The study designs a teaching model based on corpora and KGs and analyzes its specific applications in vocabulary,grammar,and discourse teaching within the Integrated English course.Additionally,the article discusses the challenges that may arise during implementation and proposes corresponding solutions.Finally,it envisions future research directions and application prospects.
基金supported by the National Natural Science Foundation of China(Grant No.:62101087)the China Postdoctoral Science Foundation(Grant No.:2021MD703942)+2 种基金the Chongqing Postdoctoral Research Project Special Funding,China(Grant No.:2021XM2016)the Science Foundation of Chongqing Municipal Commission of Education,China(Grant No.:KJQN202100642)the Chongqing Natural Science Foundation,China(Grant No.:cstc2021jcyj-msxmX0834).
文摘Drug repurposing offers a promising alternative to traditional drug development and significantly re-duces costs and timelines by identifying new therapeutic uses for existing drugs.However,the current approaches often rely on limited data sources and simplistic hypotheses,which restrict their ability to capture the multi-faceted nature of biological systems.This study introduces adaptive multi-view learning(AMVL),a novel methodology that integrates chemical-induced transcriptional profiles(CTPs),knowledge graph(KG)embeddings,and large language model(LLM)representations,to enhance drug repurposing predictions.AMVL incorporates an innovative similarity matrix expansion strategy and leverages multi-view learning(MVL),matrix factorization,and ensemble optimization techniques to integrate heterogeneous multi-source data.Comprehensive evaluations on benchmark datasets(Fdata-set,Cdataset,and Ydataset)and the large-scale iDrug dataset demonstrate that AMVL outperforms state-of-the-art(SOTA)methods,achieving superior accuracy in predicting drug-disease associations across multiple metrics.Literature-based validation further confirmed the model's predictive capabilities,with seven out of the top ten predictions corroborated by post-2011 evidence.To promote transparency and reproducibility,all data and codes used in this study were open-sourced,providing resources for pro-cessing CTPs,KG,and LLM-based similarity calculations,along with the complete AMVL algorithm and benchmarking procedures.By unifying diverse data modalities,AMVL offers a robust and scalable so-lution for accelerating drug discovery,fostering advancements in translational medicine and integrating multi-omics data.We aim to inspire further innovations in multi-source data integration and support the development of more precise and efficient strategies for advancing drug discovery and translational medicine.
基金support from the Full Bridge Fellowship for enabling the research stay at Virginia Tech.H.Xin acknowledge the financial support from the US Department of Energy,Office of Basic Energy Sciences under contract no.DE-SC0023323from the National Science Foundation through the grant 2245402 from CBET Catalysis and CDS&E programs.
文摘Knowledge graphs (KGs) offer a structured, machine-readable format for organizing complex information. In heterogeneous catalysis, where data on catalytic materials, reaction conditions, mechanisms, and synthesis routes are dispersed across diverse sources, KGs provide a semantic framework that supports data integration under the FAIR (Findable, Accessible, Interoperable, and Reusable) principles. This review aims to survey recent developments in catalysis KGs, describe the main techniques for graph construction, and highlight how artificial intelligence, particularly large language models (LLMs), enhances graph generation and query. We conducted a systematic analysis of the literature, focusing on ontology-guided text mining pipelines, graph population methods, and maintenance strategies. Our review identifies key trends: ontology-based approaches enable the automated extraction of domain knowledge, LLM-driven retrieval-augmented generation supports natural-language queries, and scalable graph architectures range from a few thousand to over a million triples. We discuss state-of-the-art applications, such as catalyst recommendation systems and reaction mechanism discovery tools, and examine the major challenges, including data heterogeneity, ontology alignment, and long-term graph curation. We conclude that KGs, when combined with AI methods, hold significant promise for accelerating catalyst discovery and knowledge management, but progress depends on establishing community standards for ontology development and maintenance. This review provides a roadmap for researchers seeking to leverage KGs to advance heterogeneous catalysis research.
文摘The article is based on language model,through the cue word engineering and agent thinking method,automatic knowledge extraction,with China accounting standards support to complete the corresponding knowledge map construction.Through the way of extracting the accounting entities and their connections in the pattern layer,the data layer is provided for the fine-tuning and optimization of the large model.Studies found that,through the reasonable application of language model,knowledge can be realized in massive financial data neural five effective extracted tuples,and complete accounting knowledge map construction.
文摘To address the underutilization of Chinese research materials in nonferrous metals,a method for constructing a domain of nonferrous metals knowledge graph(DNMKG)was established.Starting from a domain thesaurus,entities and relationships were mapped as resource description framework(RDF)triples to form the graph’s framework.Properties and related entities were extracted from open knowledge bases,enriching the graph.A large-scale,multi-source heterogeneous corpus of over 1×10^(9) words was compiled from recent literature to further expand DNMKG.Using the knowledge graph as prior knowledge,natural language processing techniques were applied to the corpus,generating word vectors.A novel entity evaluation algorithm was used to identify and extract real domain entities,which were added to DNMKG.A prototype system was developed to visualize the knowledge graph and support human−computer interaction.Results demonstrate that DNMKG can enhance knowledge discovery and improve research efficiency in the nonferrous metals field.
基金supported by the National Natural Science Foundation of China(Nos.62201419,62372357)the Natural Science Foundation of Chongqing(CSTB2023NSCQ-LMX0032)the ISN State Key Laboratory.
文摘Existing wireless networks are flooded with video data transmissions,and the demand for high-speed and low-latency video services continues to surge.This has brought with it challenges to networks in the form of congestion as well as the need for more resources and more dedicated caching schemes.Recently,Multi-access Edge Computing(MEC)-enabled heterogeneous networks,which leverage edge caches for proximity delivery,have emerged as a promising solution to all of these problems.Designing an effective edge caching scheme is critical to its success,however,in the face of limited resources.We propose a novel Knowledge Graph(KG)-based Dueling Deep Q-Network(KG-DDQN)for cooperative caching in MEC-enabled heterogeneous networks.The KGDDQN scheme leverages a KG to uncover video relations,providing valuable insights into user preferences for the caching scheme.Specifically,the KG guides the selection of related videos as caching candidates(i.e.,actions in the DDQN),thus providing a rich reference for implementing a personalized caching scheme while also improving the decision efficiency of the DDQN.Extensive simulation results validate the convergence effectiveness of the KG-DDQN,and it also outperforms baselines regarding cache hit rate and service delay.
基金supported by the Deep Earth Probe and Mineral Resources Exploration-National Science and Technology Major Project of China(Grant number:2024ZD1001105)National Natural Science Foundation of China(Grant number:42488201).
文摘Geologic time is an essential dimension in geological research,acting as a pivotal attribute that integrates data across various subdisciplines.The Geologic Time Scale(GTS)provides a formal framework for interpreting and communicating geologic time within the field of geological studies,such as macro-geological evolution and regional geologic surveys.
基金supported by Education and Research Project of Fujian Province Young and Middle-aged Teachers(JAT241035)High-level Talent Project of Fujian Medical University(XRCZX2024036)。
文摘Objectives:Chemotherapy-induced nausea and vomiting(CINV)is a common adverse effect among breast cancer patients,significantly affecting quality of life.Existing evidence on the prevention,assessment,and management of this condition is fragmented and inconsistent.This study constructed a CINV knowledge graph using a large language model(LLM)to integrate nursing and medical evidence,thereby supporting systematic clinical decision-making.Methods:A top-down approach was adopted.1)Knowledge base preparation:Nine databases and eight guideline repositories were searched up to October 2024 to include guidelines,evidence summaries,expert consensuses,and systematic reviews screened by two researchers.2)Schema design:Referring to the Unified Medical Language System,Systematized Nomenclature of Medicine-Clinical Terms,and the Nursing Intervention Classification,entity and relation types were defined to build the ontology schema.3)LLM-based extraction and integration:Using the Qwen model under the CRISPE framework,named entity recognition,relation extraction,disambiguation,and fusion were conducted to generate triples and visualize them in Neo4j.Four expert rounds ensured semantic and logical consistency.Model performance was evaluated using precision,recall,F1-score,and 95%confidence interval(95%CI)in Python 3.11.Result:A total of 47 studies were included(18 guidelines,two expert consensuses,two evidence summaries,and 25 systematic reviews).The Qwen model extracted 273 entities and 289 relations;after expert validation,238 entities and 242 relations were retained,forming 244 triples.The ontology comprised nine entity types and eight relation types.The F1-scores for named entity recognition and relation extraction were 82.97(95%CI:0.820,0.839)and 85.54(95%CI:0.844,0.867),respectively.The average node degree was 2.03,with no isolated nodes.Conclusion:The LLM-based CINV knowledge graph achieved structured integration of nursing and medical evidence,offering a novel,data-driven tool to support clinical nursing decision-making and advance intelligent healthcare.
基金supported by the China Fundamental Research Funds for the Central Universities(No.2662022XXYJ001,2662022JC004,2662023XXPY005)。
文摘As a new data management paradigm,knowledge graphs can integrate multiple data sources and achieve quick responses,reasoning and better predictions in drug discovery.Characterized by powerful contagion and a high rate of morbidity and mortality,porcine reproductive and respiratory syndrome(PRRS)is a common infectious disease in the global swine industry that causes economically great losses.Traditional Chinese medicine(TCM)has advantages in low adverse effects and a relatively affordable cost of application,and TCM is therefore conceived as a possibility to treat PRRS under the current circumstance that there is a lack of safe and effective approaches.Here,we constructed a knowledge graph containing common biomedical data from humans and Sus Scrofa as well as information from thousands of TCMs.Subsequently,we validated the effectiveness of the Sus Scrofa knowledge graph by the t-SNE algorithm and selected the optimal model(i.e.,transR)from six typical models,namely,transE,transR,DistMult,ComplEx,RESCAL and RotatE,according to five indicators,namely,MRR,MR,HITS@1,HITS@3 and HITS@10.Based on embedding vectors trained by the optimal model,anti-PRRSV TCMs were predicted by two paths,namely,VHC-Herb and VHPC-Herb,and potential anti-PRRSVTCMs were identified by retrieving the HERB database according to the phar-macological properties corresponding to symptoms of PRRS.Ultimately,Dan Shen's(Salvia miltiorrhiza Bunge)capacity to resist PRRSV infection was validated by a cell experiment in which the inhibition rate of PRRSV exceeded90%when the concentrations of Dan Shen extract were 0.004,0.008,0.016 and 0.032 mg/mL.In summary,this is the first report on the Sus Scrofa knowledge graph including TCM information,and our study reflects the important application values of deep learning on graphs in the swine industry as well as providing accessible TCM resources for PRRS.
文摘In recent years,various efforts have been devoted to advancing university education through artificial intelligence(AI).To this end,this paper introduces KCUBE,a novel framework centered on knowledge graphs(KGs)designed to enhance student advising and career planning in university courses.Owing to KCUBE,we can improve university education in the AI era by leveraging the expressiveness,operability,and interpretability of KGs.We detail a bottom-up approach for KG construction,empowering professors to develop subject-specific KGs,augmented by tools like ChatGPT,which has demonstrated promising accuracy and coverage.Based on KGs,KCUBE supports KG reasoning for applications such as automated teaching plan generation with dynamic editing capabilities.Furthermore,KCUBE offers advanced KG manipulation through 2D and 3D visualization platforms,such as virtual reality(VR)for immersive exploration of academic subjects and potential career paths.A comparative study on collaborative learning highlights the benefits of VR and KG-enhanced environments in promoting student engagement,participation,and collaborative decision-making.
基金supported by the Natural Science Foundation of Jilin Province(20220101114JC).
文摘Geographic Information System(GIS)layers contain both spatial precision and domain knowledge,making them valuable for mineral prospectivity analysis.This study proposes a task-oriented methodology to struct con-a mineral prospecting knowledge graph directly from GIS maps.The framework integrates ontology construction,spatiotemporal semantic embedding,and triple confidence evaluation.Ontologies are built from GIS layers through terminology extraction and alignment with existing standards,while spatial and temporal semantics are encoded using GeoSPARQL and the Geological Time Ontology.Graph Convolutional Networks(GCN)combined with the TransE embedding model are then applied to assess triple plausibility.A case study in the Eastern Tianshan region of Xinjiang verifies the effectiveness of the proposed method through semantic evaluation and graph-theoretic analysis.Guided by GIS,ontology construction significantly enhances the semantic fidelity and structural robustness of the prospecting knowledge graph,providing relatively reliable support for subsequent reasoning and predictive studies.
文摘Knowledge graphs convey precise semantic information that can be effectively interpreted by neural networks,and generating descriptive text based on these graphs places significant emphasis on content consistency.However,knowledge graphs are inadequate for providing additional linguistic features such as paragraph structure and expressive modes,making it challenging to ensure content coherence in generating text that spans multiple sentences.This lack of coherence can further compromise the overall consistency of the content within a paragraph.In this work,we present the generation of scientific abstracts by leveraging knowledge graphs,with a focus on enhancing both content consistency and coherence.In particular,we construct the ACL Abstract Graph Dataset(ACL-AGD)which pairs knowledge graphs with text,incorporating sentence labels to guide text structure and diverse expressions.We then implement a Siamese network to complement and concretize the entities and relations based on paragraph structure by accomplishing two tasks:graph-to-text generation and entity alignment.Extensive experiments demonstrate that the logical paragraphs generated by our method exhibit entities with a uniform position distribution and appropriate frequency.In terms of content,our method accurately represents the information encoded in the knowledge graph,prevents the generation of irrelevant content,and achieves coherent and non-redundant adjacent sentences,even with a shared knowledge graph.
文摘In the context of the“Two New”initiatives,high school mathematics instruction still grapples with three interlocking problems:knowledge fragmentation,limited cultivation of higher-order thinking,and weak alignment among teaching,learning,and assessment.To counter these challenges,we propose an Inquiry-Construction Double-Helix model that uses a domain-specific knowledge graph as its cognitive spine.The model interweaves two mutually reinforcing strands-student-driven inquiry and systematic knowledge construction-into a double-helix trajectory analogous to DNA replication.The Inquiry Strand is launched by authentic,situation-based tasks that shepherd students through the complete cycle:question→hypothesis→verification→reflection.The Construction Strand simultaneously externalizes,restructures,and internalizes core disciplinary concepts via visual,hierarchical knowledge graphs.Within the flow of a lesson,the two strands alternately dominate and scaffold each other,securing the co-development of conceptual understanding,procedural fluency,and mathematical literacy.Empirical evidence demonstrates that this model significantly enhances students’systematic knowledge integration,problem-solving transfer ability,and core mathematical competencies,offering a replicable and operable teaching paradigm and practical pathway for deepening high school mathematics classroom reform.
基金Sponsored by the National Key Research and Development Program from Ministry of Science and Technology of the People's Republic of China (Grant No.2020YFB1711403)。
文摘After the design of aerospace products is completed,a manufacturability assessment needs to be conducted based on 3D model's features in terms of modeling quality and process design,otherwise the cost of design changes will increase.Due to the poor structure and low reusability of product manufacturing feature information and assessment knowledge in the current aerospace product manufacturability assessment process,it is difficult to realize automated manufacturability assessment.To address these issues,a domain ontology model is established for aerospace product manufacturability assessment in this paper.On this basis,a structured representation method of manufacturability assessment knowledge and a knowledge graph data layer construction method are proposed.Based on the semantic information and association information expressed by the knowledge graph,a rule matching method based on subgraph matching is proposed to improve the precision and recall.Finally,applications and experiments based on the software platform verify the effectiveness of the proposed knowledge graph construction and rule matching method.
基金supported by the National Science and Technology Council(NSTC),Taiwan,under Grants Numbers 112-2622-E-029-009 and 112-2221-E-029-019.
文摘In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with large-scale knowledge graphs that contain vast numbers of entities and relations.In particular,resource-intensive embeddings often lead to increased computational costs,and may limit scalability and adaptability in practical environ-ments,such as in low-resource settings or real-world applications.This paper explores an approach to knowledge graph representation learning that leverages small,reserved entities and relation sets for parameter-efficient embedding.We introduce a hierarchical attention network designed to refine and maximize the representational quality of embeddings by selectively focusing on these reserved sets,thereby reducing model complexity.Empirical assessments validate that our model achieves high performance on the benchmark dataset with fewer parameters and smaller embedding dimensions.The ablation studies further highlight the impact and contribution of each component in the proposed hierarchical attention structure.
