Let {X\-n,n≥1} be a stationary strongly mixing random sequence satisfying E X\-1=μ, E X\+2\-1<∞ and (Var S\-n)/n→σ\+2 as n→∞ . In this paper a class of estimators of Var S\-n is studied. Th...Let {X\-n,n≥1} be a stationary strongly mixing random sequence satisfying E X\-1=μ, E X\+2\-1<∞ and (Var S\-n)/n→σ\+2 as n→∞ . In this paper a class of estimators of Var S\-n is studied. The weak consistency and asymptotic normality as well as the central limit theorem are presented.展开更多
Protoporphyrin Ⅸ(PPⅨ), a basic porphyrin system found in nature, all “porphyrin-type”tetrapyrroles with a biological function are biosynthetically derived thereof. PPⅨ is a metalloprosthetic group of numerous pro...Protoporphyrin Ⅸ(PPⅨ), a basic porphyrin system found in nature, all “porphyrin-type”tetrapyrroles with a biological function are biosynthetically derived thereof. PPⅨ is a metalloprosthetic group of numerous proteins involved in diverse metabolic and respiratory processes across all domains of life, and is thus considered essential for respiring organisms. Determining the biotic and abiotic factors that influence marine microbial growth and community structure is critical for understanding global biogeochemical cycles. Here,we present vertical profiles of intracellular PPⅨ and four derivative products(Chlorophylla/b and Pheophytin-a/b) from two coastal sediment cores, alongside ancillary geochemical and 16S rRNA microbial community data. Our findings indicated that PPⅨ is present in the natural sediment environment and displays a decreasing trend with depth, revealing a significant positive correlation with both organic matter and microbial abundance. Cooccurrence networks revealed that the environmental distribution of PPⅨ was positively correlated with the microbial porphyrin producer(high genetic completeness), but negatively correlated with auxotrophs(absence or low genetic completeness). It emphasized the critical role of PPⅨ as a biological molecule involved in key physiological processes. These results suggest that PPⅨ is a prominent component of the shared extracellular metabolite pool, especially in anoxic marine sediments where it exists at physiologically relevant concentrations for microbial metabolism. This study highlighted the significance of PPⅨ in microbial ecology and its potential impact on biogeochemical cycles in marine sedimentary environments.展开更多
To the Editor,Systemic lupus erythematosus(SLE)is an autoimmune disease characterized by multisystem involvement.In addition to butterfly erythema,photosensitivity,arthritis,and other clinical manifestations,SLE can a...To the Editor,Systemic lupus erythematosus(SLE)is an autoimmune disease characterized by multisystem involvement.In addition to butterfly erythema,photosensitivity,arthritis,and other clinical manifestations,SLE can also result in hematological complications,such as coagulopathy.Acquired hemophilia has been documented in patients with SLE,attributed to the presence of inhibitors against coagulation factors in the circulating blood.1 Furthermore,deficiency of factor XII(FXII)has been reported in patient with SLE in the absence of FXII inhibitors.2,3 However,there have been no reports of a deficiency of FIX without the presence of FIX inhibitors in patients with SLE.In this report,we present a case of a patient with SLE who exhibited recurrent mucosal bleeding attributed to reduced activity of FIX without detectable inhibitors.展开更多
目的:比较Fuji IX GP玻璃离子水门汀、3M ESPE Filtek^(TM) Bulk Fill Flowable树脂、VOCO Polofil Supra树脂及Beautiful Flow Plus F03树脂修复根面龋的临床疗效。方法:选取后牙根面龋患者128例(422颗患牙),按照充填修复材料分为A组(F...目的:比较Fuji IX GP玻璃离子水门汀、3M ESPE Filtek^(TM) Bulk Fill Flowable树脂、VOCO Polofil Supra树脂及Beautiful Flow Plus F03树脂修复根面龋的临床疗效。方法:选取后牙根面龋患者128例(422颗患牙),按照充填修复材料分为A组(Fuji IX GP玻璃离子水门汀修复)34例、B组(3M ESPE Filtek^(TM) Bulk Fill Flowable树脂修复)29例、C组(VOCO Polofil Supra树脂修复)35例、D组(Beautiful Flow Plus F03树脂修复)30例。手术治疗后随访6个月,比较4组患者牙髓活力、材料密合性、充填物表面磨损及充填物完好性情况。结果:术后6个月,4组患者牙髓活力均正常。A组、B组、C组、D组材料密合性好的患牙占比分别为75.49%、90.74%、88.57%、97.20%,A组低于B组、C组、D组,差异均有统计学意义(P<0.05);B组与D组、C组与D组比较,差异均有统计学意义(P<0.05),B、C组之间差异无统计学意义(P>0.05)。A组、B组、C组、D组充填物表面无磨损的患牙占比分别为77.45%、95.37%、94.29%、99.07%,A组占比低于B组、C组及D组,差异均有统计学意义(P<0.05);B组与C组、B组与D组、C组与D组间比较,差异均无统计学意义(P>0.05)。A组、B组、C组、D组充填物完好的患牙占比分别为91.18%、97.22%、97.14%、99.07%,A组占比低于D组,差异有统计学意义(P<0.05)。其他组之间比较,差异均无统计学意义(P>0.05)。结论:4种材料对牙髓活力均无影响,树脂类材料在密合性、表面磨损情况以及完好性上均优于Fuji IX GP玻璃离子水门汀。三种树脂类材料中Beautiful Flow Plus F03在密闭性方面优于其他两种树脂。展开更多
In this paper, a notion of negative side ρ \|mixing ( ρ\+- \|mixing) which can be regarded as asymptotic negative association is defined, and some Rosenthal type inequalities for ρ\+- \|mixing random fields are est...In this paper, a notion of negative side ρ \|mixing ( ρ\+- \|mixing) which can be regarded as asymptotic negative association is defined, and some Rosenthal type inequalities for ρ\+- \|mixing random fields are established. The complete convergence and almost sure summability on the convergence rates with respect to the strong law of large numbers are also discussed for ρ\+-\| mixing random fields. The results obtained extend those for negatively associated sequences and ρ\+*\| mixing random fields.展开更多
文摘Let {X\-n,n≥1} be a stationary strongly mixing random sequence satisfying E X\-1=μ, E X\+2\-1<∞ and (Var S\-n)/n→σ\+2 as n→∞ . In this paper a class of estimators of Var S\-n is studied. The weak consistency and asymptotic normality as well as the central limit theorem are presented.
基金supported by the Doctoral Research Initiation Fund Project of Hebei Normal University(No.L2025B19)PhD Fellowship of the State Key Laboratory of Marine Environmental Science at Xiamen University.
文摘Protoporphyrin Ⅸ(PPⅨ), a basic porphyrin system found in nature, all “porphyrin-type”tetrapyrroles with a biological function are biosynthetically derived thereof. PPⅨ is a metalloprosthetic group of numerous proteins involved in diverse metabolic and respiratory processes across all domains of life, and is thus considered essential for respiring organisms. Determining the biotic and abiotic factors that influence marine microbial growth and community structure is critical for understanding global biogeochemical cycles. Here,we present vertical profiles of intracellular PPⅨ and four derivative products(Chlorophylla/b and Pheophytin-a/b) from two coastal sediment cores, alongside ancillary geochemical and 16S rRNA microbial community data. Our findings indicated that PPⅨ is present in the natural sediment environment and displays a decreasing trend with depth, revealing a significant positive correlation with both organic matter and microbial abundance. Cooccurrence networks revealed that the environmental distribution of PPⅨ was positively correlated with the microbial porphyrin producer(high genetic completeness), but negatively correlated with auxotrophs(absence or low genetic completeness). It emphasized the critical role of PPⅨ as a biological molecule involved in key physiological processes. These results suggest that PPⅨ is a prominent component of the shared extracellular metabolite pool, especially in anoxic marine sediments where it exists at physiologically relevant concentrations for microbial metabolism. This study highlighted the significance of PPⅨ in microbial ecology and its potential impact on biogeochemical cycles in marine sedimentary environments.
基金supported by a grant from Peking University Shougang Hospital Research Funds,Grant/Award Number:SGYYZ202403.
文摘To the Editor,Systemic lupus erythematosus(SLE)is an autoimmune disease characterized by multisystem involvement.In addition to butterfly erythema,photosensitivity,arthritis,and other clinical manifestations,SLE can also result in hematological complications,such as coagulopathy.Acquired hemophilia has been documented in patients with SLE,attributed to the presence of inhibitors against coagulation factors in the circulating blood.1 Furthermore,deficiency of factor XII(FXII)has been reported in patient with SLE in the absence of FXII inhibitors.2,3 However,there have been no reports of a deficiency of FIX without the presence of FIX inhibitors in patients with SLE.In this report,we present a case of a patient with SLE who exhibited recurrent mucosal bleeding attributed to reduced activity of FIX without detectable inhibitors.
文摘目的:比较Fuji IX GP玻璃离子水门汀、3M ESPE Filtek^(TM) Bulk Fill Flowable树脂、VOCO Polofil Supra树脂及Beautiful Flow Plus F03树脂修复根面龋的临床疗效。方法:选取后牙根面龋患者128例(422颗患牙),按照充填修复材料分为A组(Fuji IX GP玻璃离子水门汀修复)34例、B组(3M ESPE Filtek^(TM) Bulk Fill Flowable树脂修复)29例、C组(VOCO Polofil Supra树脂修复)35例、D组(Beautiful Flow Plus F03树脂修复)30例。手术治疗后随访6个月,比较4组患者牙髓活力、材料密合性、充填物表面磨损及充填物完好性情况。结果:术后6个月,4组患者牙髓活力均正常。A组、B组、C组、D组材料密合性好的患牙占比分别为75.49%、90.74%、88.57%、97.20%,A组低于B组、C组、D组,差异均有统计学意义(P<0.05);B组与D组、C组与D组比较,差异均有统计学意义(P<0.05),B、C组之间差异无统计学意义(P>0.05)。A组、B组、C组、D组充填物表面无磨损的患牙占比分别为77.45%、95.37%、94.29%、99.07%,A组占比低于B组、C组及D组,差异均有统计学意义(P<0.05);B组与C组、B组与D组、C组与D组间比较,差异均无统计学意义(P>0.05)。A组、B组、C组、D组充填物完好的患牙占比分别为91.18%、97.22%、97.14%、99.07%,A组占比低于D组,差异有统计学意义(P<0.05)。其他组之间比较,差异均无统计学意义(P>0.05)。结论:4种材料对牙髓活力均无影响,树脂类材料在密合性、表面磨损情况以及完好性上均优于Fuji IX GP玻璃离子水门汀。三种树脂类材料中Beautiful Flow Plus F03在密闭性方面优于其他两种树脂。
文摘In this paper, a notion of negative side ρ \|mixing ( ρ\+- \|mixing) which can be regarded as asymptotic negative association is defined, and some Rosenthal type inequalities for ρ\+- \|mixing random fields are established. The complete convergence and almost sure summability on the convergence rates with respect to the strong law of large numbers are also discussed for ρ\+-\| mixing random fields. The results obtained extend those for negatively associated sequences and ρ\+*\| mixing random fields.
