On September 27 this year, in the golden autumn, more than 1,000 overseas travel agents and tourists and over 100 Chinese and foreign reporters converged in Zhengzhou City of China’s Henan Province, and joined thousa...On September 27 this year, in the golden autumn, more than 1,000 overseas travel agents and tourists and over 100 Chinese and foreign reporters converged in Zhengzhou City of China’s Henan Province, and joined thousands of local people in celebrating the ’93 World Tourism Day. World Tourism Day, which was set by the World Tourism Organization in September 1979, is a festival of展开更多
The"spleen"in traditional Chinese medicine is the"acquired foundation"and the"source of qi and blood biochemistry".Strengthening the"spleen"is one of the important treat‐ment m...The"spleen"in traditional Chinese medicine is the"acquired foundation"and the"source of qi and blood biochemistry".Strengthening the"spleen"is one of the important treat‐ment methods in traditional Chinese medicine;The gut microbiota has been a hot topic in modern scientific research in recent years,and its nutritional and immune functions correspond to some of the functions of the spleen in traditional Chinese medicine.In terms of philosophy,traditional Chinese medicine emphasizes the balance between the spleen and the gut microbiota,emphasizing the importance of supporting the right and eliminating evil,preventing diseases before they occur,seeking the root cause of treat‐ment,and adapting measures to the three causes;Clinically,the treatment of obesity,con‐stipation,diarrhea and other diseases by invigorating the spleen and the treatment mechanism of acupuncture and moxibustion,chiropractic and invigorating the spleen are all related to microecology.This article combines relevant literature on traditional Chinese medicine's"spleen"and"spleen health"to explore the treatment concept,clinical application,and correlation with intestinal microbiota of traditional Chinese medicine's"spleen health".It also elaborates on the latest literature,aiming to exchange ideas with peers and promote research on the microbiota of traditional Chinese medicine's"spleen".展开更多
Under the influence of academic theories of numerous physicians of TCM such as Li Gao and Li Zhong-zi in antient China, Professor Jia Chun-sheng proposed the academic thought of tonifying spleen and kidney in combinat...Under the influence of academic theories of numerous physicians of TCM such as Li Gao and Li Zhong-zi in antient China, Professor Jia Chun-sheng proposed the academic thought of tonifying spleen and kidney in combination with acupuncture based on his clinical experience for decades. In clinical practice of acupuncture, Zhongwan （中脘 CV 12）, bilateral Tianshu （天枢 ST 25）, Qihai （气海 CV 6）, Guanyuan （关元 CV4） are often selected to invigorate spleen so as to nourish original qi and to treat both spleen and kidney. The above-mentioned five acupoints form a pattern similar to a star according to their location distribution, so it is called the starlike selection method of acupoints, which attaches importance to spleen and kidney （original qi）. Many diseases, especially internal injuries, are often treated with the starlike acupuncture manipulation combined with acupuncture at other acupoints, which achieves good clinical efficacy.展开更多
AIM： TO observe the therapeutic effects of new traditional Chinese medicine （TClVl） therapy on coagulation disorder and accompanying intractable jaundice in HBV-related liver cirrhosis patients. METHODS： Using str...AIM： TO observe the therapeutic effects of new traditional Chinese medicine （TClVl） therapy on coagulation disorder and accompanying intractable jaundice in HBV-related liver cirrhosis patients. METHODS： Using stratified random sampling according to fibrinogen （Fib） levels, 145 liver cirrhosis patients due to hepatitis B complicated by coagulation disorder were treated. Of them, 70 in research group were treated with TCM by ＂nourishing yin, cooling blood and invigorating blood circulation＂ and Western medicine, 75 in control group were treated with conventional Western medicine. The indexes of liver function, coagulation function and bleeding events were observed and compared. RESULTS： The prothrombin time （PT） was shorter and the fibrinogen （Fib） level was higher in the research group than in the control group （Fib = 1.6-2.0 g/L, 1.1-1.5 g/L, and ≤ 1.0 g/L）. The total bilirubin （TBIL） level was significantly lower in the research group than in the control group, except for the subgroup of FIB ≤ 1.0 g/L. CONCLUSION： TCM therapy can improve coagulation fuction and decrease TBIL.展开更多
Objective: To explore the mechanism of action of Juanbi Capsules (蠲痹胶囊), a Chinese medicine for invigorating the kidney and replenishing qi, in preventing osteoarthritis of the knee in rabbits. Methods: Seventy-tw...Objective: To explore the mechanism of action of Juanbi Capsules (蠲痹胶囊), a Chinese medicine for invigorating the kidney and replenishing qi, in preventing osteoarthritis of the knee in rabbits. Methods: Seventy-two 4-month-old, Japanese long-eared white rabbits were randomly divided into 6 groups: control (group A), model (group B), Chinese drug; high-dose (group C), Chinese drug; mid-dose (group D), Chinese drug; low-dose (group E), and drug control (group F). With the exception of the rabbits in group A, each rabbit was subjected to plaster cast fixation for 6 weeks to induce osteoarthritis. In addition, rabbits were administrated with an intragastric injection of the Chinese drug (groups C, D and E) or an aminoglucose hydrochloride capsule (group F) for 4 weeks. Blood was drawn from the central ear artery for serum MMP-2 and MMP-9 concentrations, and the knee joint cartilage was harvested for gross observation and light microscopy. Results: There were significant differences in serum MMP-2 and MMP-9 concentrations between group B and groups C, D and E (P<0.05), with no significant differences between groups D and F. Histological results showed various changes in tissue staining with treatment, with osteophyte and bone cyst formation, and superficial erosion in the articular surface of the cartilage; in some cases, the defect reached the mid-layer of the cartilage, and these changes were lower than those in the model group. Conclusion: Juanbi Capsules assist in preventing osteoarthritis in the rabbit, possibly by decreasing serum MMP-2 and MMP-9 levels.展开更多
ABSTRACT The spatial and temporal global distribution of deep clouds was analyzed using a four-year dataset （2007-10） based on observations from CloudSat and CALIPSO. Results showed that in the Northern Hemisphere,...ABSTRACT The spatial and temporal global distribution of deep clouds was analyzed using a four-year dataset （2007-10） based on observations from CloudSat and CALIPSO. Results showed that in the Northern Hemisphere, the number of deep cloud systems （DCS） reached a maximum in summer and a minimum in winter. Seasonal variations in the number of DCS varied zonally in the Southern Hemisphere. DCS occurred most frequently over central Africa, the northern parts of South America and Australia, and Tibet. The mean cloud-top height of deep cloud cores （TDCC） decreased toward high latitudes in all seasons. DCS with the highest TDCC and deepest cores occurred over east and south Asian monsoon regions, west-central Africa and northern South America. The width of DCS （WDCS） increased toward high latitudes in all seasons. In general, DCS were more developed in the horizontal than in the vertical direction over high latitudes and vice versa over lower lat- itudes. Findings from this study show that different mechanisms are behind the development of DCS at different latitudes. Most DCS at low latitudes are deep convective clouds which are highly developed in the vertical direction but cover a rela tively small area in the horizontal direction; these DCS have the highest TDCC and smallest WDCS. The DCS at midlatitudes are more likely to be caused by cyclones, so they have less vertical development than DCS at low latitudes. DCS at high latitudes are mainly generated by large frontal systems, so they have the largest WDCS and the smallest TDCC.展开更多
Objective:To examine the effects of modified Shenmai Yin on invigorating vital energy, promoting blood flow, and protection against neural impairment in an endotoxin-induced shock rat model. Methods: Ninety-six SD rat...Objective:To examine the effects of modified Shenmai Yin on invigorating vital energy, promoting blood flow, and protection against neural impairment in an endotoxin-induced shock rat model. Methods: Ninety-six SD rats were randomly divided into four groups: sham operation (saline 20 ml/kg), shock model (lipopolysaccharide, LPS, 8 mg/kg), Reformed Shengmai Yin (加味生脉饮 Pulse-activating Decoction) (LPS 8 mg/kg + reformed Shengmai Yin Injection 10 ml/kg), and dexamethasone (LPS 8 mg/kg + dexamethasone 5 mg/kg) groups. Each group was subdivided into 1 h, 2 h, 3 h, and 6 h time points for observation. The carotid artery was separated and connected with a biological functional system to monitor mean arterial pressure (MAP). Brain water levels, malonaldehyde (MDA) content, and superoxide dismutase (SOD) activity were also determined. Results: In the shock model group, MAP was progressively decreased after injection of LPS, brain water and MDA contents were increased, brain SOD activity was decreased, and capillary vessel edema in brain tissue was also observed. All these parameters were improved significantly in both treatment groups, although the effects were more marked with Shengmai Yin than with dexamethasone. Conclusion: Modified Shengmai Yin exhibits strong anti-shock and neuroprotective effects against Endotoxininduced shock.展开更多
OBJECTIVE: To observe the effect of tonifying liver and kidney-essence herbs on expression of a nerve regeneration inhibitor, Nogo for neuron A (No- go-A), and its associated signaling molecule, low-af- finity neurotr...OBJECTIVE: To observe the effect of tonifying liver and kidney-essence herbs on expression of a nerve regeneration inhibitor, Nogo for neuron A (No- go-A), and its associated signaling molecule, low-af- finity neurotrophin receptor p75 (p75TR), in rats with cerebral ischemic stroke (CIS), with the aim of exploring the possible mechanism of tonifying liver and kidney-essence herbs in recovery following in- jury to the central nervous system. METHODS: A cerebral ischemic stroke model in SD rats was established with the suture-occlusion method. Successful model rats were divided into placebo and herb groups at random; sham-operat- ed and control groups were set up simultaneously.Each of these groups was divided into six sub- groups at random. Expression of Nogo-A and p75TR was evaluated with immunofluorescence microsco- py at days 3, and weeks1, 2, 3, 4 and 8 after adminis- tration. RESULTS: Tonifying liver and kidney-essence herbs suppressed the expression of Nogo-A and p75T (P〈0.05 and P〈0.01, respectively). CONCLUSION: Suppressing the expression of No- go-A and p75NTR is possibly one of the mechanisms underlying the ability of tonifying liver and kid- ney-essence herbs to promote recovery of the in- jured central nervous system.展开更多
Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction.＂Warming yang and inv...Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction.＂Warming yang and invigorating qi＂ acupuncture treatment has been shown to reduce serum inflammatory cytokine expression and increase transforming growth factor beta expression in rats with experimental autoimmune myasthenia gravis.However,few studies have addressed the effects of this type of acupuncture on the acetylcholine receptors at the neuromuscular junction.Here,we used confocal laser scanning microscopy to examine the area and density of immunoreactivity for an antibody to the nicotinic acetylcholine receptor at the neuromuscular junction in the phrenic nerve of rats with experimental autoimmune myasthenia gravis following ＂warming yang and invigorating qi＂ acupuncture therapy.Needles were inserted at acupressure points Shousanli（LI10）,Zusanli（ST36）,Pishu（BL20）,and Shenshu（BL23） once daily for 7 consecutive days.The treatment was repeated after 1 day of rest.We found that area and the integrated optical density of the immunoreactivity for the acetylcholine receptor at the neuromuscular junction of the phrenic nerve was significantly increased following acupuncture treatment.This outcome of the acupuncture therapy was similar to that of the cholinesterase inhibitor pyridostigmine bromide.These findings suggest that ＂warming yang and invigorating qi＂ acupuncture treatment increases acetylcholine receptor expression at the neuromuscular junction in a rat model of autoimmune myasthenia gravis.展开更多
Seed priming has proved to be an effective pre-germination seed invigoration technique for different crops to improve seed and seedling performance under different abiotic stresses.In Bangladesh,winter rice is very of...Seed priming has proved to be an effective pre-germination seed invigoration technique for different crops to improve seed and seedling performance under different abiotic stresses.In Bangladesh,winter rice is very often exposed to cold waves just after sowing in the nursery bed resulting in poor seed germination and seedling emergence,yellowish and thin seedlings production,and a very low survival rate.Seed priming may mitigate the cold stress during seed germination and seedling emergence and helps in the quality seedling production of winter rice.To evaluate the efficacy of different seed priming techniques in increasing seedling emergence,growth,vigor and survivability of winter rice cultivars under cold stress,a pot experiment was conducted at the Department of Agronomy,Bangladesh Agricultural University during December 2018 to January 2019.The experiment comprised two factors,(A)Winter rice variety namely,(i)BRRI dhan29 and (ii)BRRI dhan36;(B)Seed priming agent namely (i)Control(no priming),(ii)20000 ppm NaCl,(iii)30000 ppm NaCl,(iv)20000 ppm KCl,(v)30000 ppm KCl,(vi)20000 ppm CaCl2,(vii)30000 ppm CaCl2,(viii)50 ppm CuSO4,(ix)75 ppm CuSO_(4),(x)10000 ppm ZnSO4,(xi)15000 ppm ZnSO4,(xii)2 ppm Na2MoO4,(xiii)3 ppm Na2MoO4,(xiv)100 ppm PEG(Polyethylene glycol 4000)and (xv)150 ppm PEG.Seeds were sown on two different dates viz.,1st December and 1st January so that seedlings are exposed to cold stress at different stages.The experiment was laid out in a completely randomized design(CRD)with three replications.Results indicated that(in most of the cases)seed priming has a positive impact on seedling emergence rate(%),root length,shoot length,root shoot ratio,root dry weight,shoot dry weight,seedling dry weight and survival rate(%).Among the priming agents,KCl and CaCl2 performed best;while priming with NaCl and PEG showed no advantages over no priming for both the sowing dates.In general,BRRI dhan36 performed better than BRRI dhan29 in terms of seedling growth because of its higher tolerance to cold stress.But,both the varieties performed similarly in terms of emergence rate and survival rate.Thus,priming is an effective tool to increase seed germination,better seedling growth,and higher seedling survivability of winter rice under cold stress,and KCl(20000 ppm)or CaCl2(20000 ppm)can be considered as a viable priming agent.展开更多
The therapeutic effects in treating the intermediate and late rheumatoid arthritis by supplementing the kidney and invigorating blood circulation were observed. In the 43 cases of the treatment group, No. 2 Qu Feng Sh...The therapeutic effects in treating the intermediate and late rheumatoid arthritis by supplementing the kidney and invigorating blood circulation were observed. In the 43 cases of the treatment group, No. 2 Qu Feng Shi Ling capsules (祛风湿灵胶囊2号) and Fenbid (芬必得) were prescribed, while in the 39 cases of the control group Lei Gong Teng Tablets (雷公藤总甙片) and Fenbid were given. The results showed that the total effective rate in the treatment group was more satisfactory than that in the control (P<0.05 or P<0.01). With less toxic effects, the former could better improve the local swelling and lower the blood viscosity.展开更多
Objective:To determine the therapeutic effect of Danggui Shaoyao San with Huangqi on rats with nephrotic syndrome(NS)was discussed,and the scientific connotation of TCM treatment principle was elaborated,so as to prov...Objective:To determine the therapeutic effect of Danggui Shaoyao San with Huangqi on rats with nephrotic syndrome(NS)was discussed,and the scientific connotation of TCM treatment principle was elaborated,so as to provide experimental basis for its clinical application.Methods:The NS rat model was established by iv administration of adriamycin;The rats were divided into model group,Danggui Shaoyao San group,Danggui Shaoyao San with Huangqi group,Huangqi group and positive drug group,with 10 rats in control group;The best dosage ratio of Danggui Shaoyao San and Huangqi was screened by Excel;24 h urine protein was measured by BCA method;The electrolyte level was detected by automatic biochemical analyzer;In serum Urea nitrogen(BUN),Creatinine(SCr),Total cholesterol(TC),Triglyceride(TG),Total protein(TP),Albumin(ALB),Immunoglobulin M(Ig-M)and Immunoglobulin G(Ig-G)were detected by the kit;hematoxylin-eosin staining was used to observe the renal morphology;The Total water content(TBW),Extracellular water content(ECF)and Intracellular water content(ICF)were measured by experimental animal body composition analyzer.Results:Compared with the model group,the urine protein in the modified Astragalus group of Danggui Shaoyao Powder was significantly decreased(P<0.01);Urine electrolytes were significantly decreased and serum electrolytes were significantly increased(P<0.01);Serum BUN,SCR,TC and TG were significantly decreased(P<0.01),while TP,ALB,TBW and ICF were significantly increased(P<0.01);The levels of Ig-M and Ig-G were significantly increased(P<0.01),TBW and ICF were significantly increased,and ECF was significantly decreased(P<0.01);Histopathology showed that the pathological changes of renal tissue were obviously alleviated;The improvement of each index was better than that of Danggui Shaoyao San group and Huangqi group.Conclusion:Danggui Shaoyao San with Huangqi group can significantly improve the edema,proteinuria,blood lipid and immune function of NS rats,and the effect is better than that of Danggui Shaoyao San group and Huangqi group.It has the best therapeutic effect on NS,which indicates that Huangqi plays a key synergistic effect on Danggui Shaoyao San,which verifies the scientific connotation of"Yiqi Huoxue Lishui"in the treatment of NS.展开更多
Chronic kidney disease is a general term for various types of renal diseases characterized by a long course of disease and difficulty in early detection.It is one of the social diseases that need to be solved urgently...Chronic kidney disease is a general term for various types of renal diseases characterized by a long course of disease and difficulty in early detection.It is one of the social diseases that need to be solved urgently and its pathogenesis and treatment have always been a hotspot for researchers.Studies have shown that traditional Chinese medicine(TCM)can effectively delay the progress of chronic kidney disease.According to the clinical experience of national famous TCM physicians,based on its pathogenesis of"kidney deficiency as the foundation and poison as the target",chronic kidney disease can be treated by invigorating the kidney and removing toxic.Based on the above background,this paper summarizes the research progress of invigorating the kidney and removing toxic in delaying chronic kidney disease from multiple mechanisms and pathways in modern research.展开更多
Recent released Chinese Ski Industry White Paper by Asian International Trade Show for Sporting Equipements and Fashion(ISPO)pointed out that ski industry in China received customers of 12.5 million person times in 20...Recent released Chinese Ski Industry White Paper by Asian International Trade Show for Sporting Equipements and Fashion(ISPO)pointed out that ski industry in China received customers of 12.5 million person times in 2015,and many ski resorts had more than200,000 vistors.Zhao Yinggang,展开更多
Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, ...Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).展开更多
Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, ...Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).展开更多
Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, ...Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).展开更多
Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, ...Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).展开更多
Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, ...Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).展开更多
文摘On September 27 this year, in the golden autumn, more than 1,000 overseas travel agents and tourists and over 100 Chinese and foreign reporters converged in Zhengzhou City of China’s Henan Province, and joined thousands of local people in celebrating the ’93 World Tourism Day. World Tourism Day, which was set by the World Tourism Organization in September 1979, is a festival of
文摘The"spleen"in traditional Chinese medicine is the"acquired foundation"and the"source of qi and blood biochemistry".Strengthening the"spleen"is one of the important treat‐ment methods in traditional Chinese medicine;The gut microbiota has been a hot topic in modern scientific research in recent years,and its nutritional and immune functions correspond to some of the functions of the spleen in traditional Chinese medicine.In terms of philosophy,traditional Chinese medicine emphasizes the balance between the spleen and the gut microbiota,emphasizing the importance of supporting the right and eliminating evil,preventing diseases before they occur,seeking the root cause of treat‐ment,and adapting measures to the three causes;Clinically,the treatment of obesity,con‐stipation,diarrhea and other diseases by invigorating the spleen and the treatment mechanism of acupuncture and moxibustion,chiropractic and invigorating the spleen are all related to microecology.This article combines relevant literature on traditional Chinese medicine's"spleen"and"spleen health"to explore the treatment concept,clinical application,and correlation with intestinal microbiota of traditional Chinese medicine's"spleen health".It also elaborates on the latest literature,aiming to exchange ideas with peers and promote research on the microbiota of traditional Chinese medicine's"spleen".
文摘Under the influence of academic theories of numerous physicians of TCM such as Li Gao and Li Zhong-zi in antient China, Professor Jia Chun-sheng proposed the academic thought of tonifying spleen and kidney in combination with acupuncture based on his clinical experience for decades. In clinical practice of acupuncture, Zhongwan （中脘 CV 12）, bilateral Tianshu （天枢 ST 25）, Qihai （气海 CV 6）, Guanyuan （关元 CV4） are often selected to invigorate spleen so as to nourish original qi and to treat both spleen and kidney. The above-mentioned five acupoints form a pattern similar to a star according to their location distribution, so it is called the starlike selection method of acupoints, which attaches importance to spleen and kidney （original qi）. Many diseases, especially internal injuries, are often treated with the starlike acupuncture manipulation combined with acupuncture at other acupoints, which achieves good clinical efficacy.
基金Science and Technology Agency of Guangdong Province,NO.2008B030301041
文摘AIM： TO observe the therapeutic effects of new traditional Chinese medicine （TClVl） therapy on coagulation disorder and accompanying intractable jaundice in HBV-related liver cirrhosis patients. METHODS： Using stratified random sampling according to fibrinogen （Fib） levels, 145 liver cirrhosis patients due to hepatitis B complicated by coagulation disorder were treated. Of them, 70 in research group were treated with TCM by ＂nourishing yin, cooling blood and invigorating blood circulation＂ and Western medicine, 75 in control group were treated with conventional Western medicine. The indexes of liver function, coagulation function and bleeding events were observed and compared. RESULTS： The prothrombin time （PT） was shorter and the fibrinogen （Fib） level was higher in the research group than in the control group （Fib = 1.6-2.0 g/L, 1.1-1.5 g/L, and ≤ 1.0 g/L）. The total bilirubin （TBIL） level was significantly lower in the research group than in the control group, except for the subgroup of FIB ≤ 1.0 g/L. CONCLUSION： TCM therapy can improve coagulation fuction and decrease TBIL.
基金supported by special-purpose scientific research plan of the Education Department of Shaanxi Province (09JK411)the foundation of the Education Department of Shaanxi Province for Key Discipline and The State Administration of TCM for Key Specialized Subject Construction
文摘Objective: To explore the mechanism of action of Juanbi Capsules (蠲痹胶囊), a Chinese medicine for invigorating the kidney and replenishing qi, in preventing osteoarthritis of the knee in rabbits. Methods: Seventy-two 4-month-old, Japanese long-eared white rabbits were randomly divided into 6 groups: control (group A), model (group B), Chinese drug; high-dose (group C), Chinese drug; mid-dose (group D), Chinese drug; low-dose (group E), and drug control (group F). With the exception of the rabbits in group A, each rabbit was subjected to plaster cast fixation for 6 weeks to induce osteoarthritis. In addition, rabbits were administrated with an intragastric injection of the Chinese drug (groups C, D and E) or an aminoglucose hydrochloride capsule (group F) for 4 weeks. Blood was drawn from the central ear artery for serum MMP-2 and MMP-9 concentrations, and the knee joint cartilage was harvested for gross observation and light microscopy. Results: There were significant differences in serum MMP-2 and MMP-9 concentrations between group B and groups C, D and E (P<0.05), with no significant differences between groups D and F. Histological results showed various changes in tissue staining with treatment, with osteophyte and bone cyst formation, and superficial erosion in the articular surface of the cartilage; in some cases, the defect reached the mid-layer of the cartilage, and these changes were lower than those in the model group. Conclusion: Juanbi Capsules assist in preventing osteoarthritis in the rabbit, possibly by decreasing serum MMP-2 and MMP-9 levels.
基金supported by the National Natural Science Foundation of China (Grant No.41375080)the National Program on Key Basic Research Project of China (Grant Nos.2011CB403405 and 2013CB955804)the US Department of Energy Atmospheric System Research Program (DESC0007171)
文摘ABSTRACT The spatial and temporal global distribution of deep clouds was analyzed using a four-year dataset （2007-10） based on observations from CloudSat and CALIPSO. Results showed that in the Northern Hemisphere, the number of deep cloud systems （DCS） reached a maximum in summer and a minimum in winter. Seasonal variations in the number of DCS varied zonally in the Southern Hemisphere. DCS occurred most frequently over central Africa, the northern parts of South America and Australia, and Tibet. The mean cloud-top height of deep cloud cores （TDCC） decreased toward high latitudes in all seasons. DCS with the highest TDCC and deepest cores occurred over east and south Asian monsoon regions, west-central Africa and northern South America. The width of DCS （WDCS） increased toward high latitudes in all seasons. In general, DCS were more developed in the horizontal than in the vertical direction over high latitudes and vice versa over lower lat- itudes. Findings from this study show that different mechanisms are behind the development of DCS at different latitudes. Most DCS at low latitudes are deep convective clouds which are highly developed in the vertical direction but cover a rela tively small area in the horizontal direction; these DCS have the highest TDCC and smallest WDCS. The DCS at midlatitudes are more likely to be caused by cyclones, so they have less vertical development than DCS at low latitudes. DCS at high latitudes are mainly generated by large frontal systems, so they have the largest WDCS and the smallest TDCC.
基金supported by a grant from National Natural Science Foundation of China (No.30672737)
文摘Objective:To examine the effects of modified Shenmai Yin on invigorating vital energy, promoting blood flow, and protection against neural impairment in an endotoxin-induced shock rat model. Methods: Ninety-six SD rats were randomly divided into four groups: sham operation (saline 20 ml/kg), shock model (lipopolysaccharide, LPS, 8 mg/kg), Reformed Shengmai Yin (加味生脉饮 Pulse-activating Decoction) (LPS 8 mg/kg + reformed Shengmai Yin Injection 10 ml/kg), and dexamethasone (LPS 8 mg/kg + dexamethasone 5 mg/kg) groups. Each group was subdivided into 1 h, 2 h, 3 h, and 6 h time points for observation. The carotid artery was separated and connected with a biological functional system to monitor mean arterial pressure (MAP). Brain water levels, malonaldehyde (MDA) content, and superoxide dismutase (SOD) activity were also determined. Results: In the shock model group, MAP was progressively decreased after injection of LPS, brain water and MDA contents were increased, brain SOD activity was decreased, and capillary vessel edema in brain tissue was also observed. All these parameters were improved significantly in both treatment groups, although the effects were more marked with Shengmai Yin than with dexamethasone. Conclusion: Modified Shengmai Yin exhibits strong anti-shock and neuroprotective effects against Endotoxininduced shock.
基金Suppored by Special Project on Traditional Chinese Medicine Science and Technology of State Administration of Traditional Chinese Medicine of the PRC(No.06-07LB21)
文摘OBJECTIVE: To observe the effect of tonifying liver and kidney-essence herbs on expression of a nerve regeneration inhibitor, Nogo for neuron A (No- go-A), and its associated signaling molecule, low-af- finity neurotrophin receptor p75 (p75TR), in rats with cerebral ischemic stroke (CIS), with the aim of exploring the possible mechanism of tonifying liver and kidney-essence herbs in recovery following in- jury to the central nervous system. METHODS: A cerebral ischemic stroke model in SD rats was established with the suture-occlusion method. Successful model rats were divided into placebo and herb groups at random; sham-operat- ed and control groups were set up simultaneously.Each of these groups was divided into six sub- groups at random. Expression of Nogo-A and p75TR was evaluated with immunofluorescence microsco- py at days 3, and weeks1, 2, 3, 4 and 8 after adminis- tration. RESULTS: Tonifying liver and kidney-essence herbs suppressed the expression of Nogo-A and p75T (P〈0.05 and P〈0.01, respectively). CONCLUSION: Suppressing the expression of No- go-A and p75NTR is possibly one of the mechanisms underlying the ability of tonifying liver and kid- ney-essence herbs to promote recovery of the in- jured central nervous system.
基金supported by the National Natural Science Foundation of China,No.81173344
文摘Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction.＂Warming yang and invigorating qi＂ acupuncture treatment has been shown to reduce serum inflammatory cytokine expression and increase transforming growth factor beta expression in rats with experimental autoimmune myasthenia gravis.However,few studies have addressed the effects of this type of acupuncture on the acetylcholine receptors at the neuromuscular junction.Here,we used confocal laser scanning microscopy to examine the area and density of immunoreactivity for an antibody to the nicotinic acetylcholine receptor at the neuromuscular junction in the phrenic nerve of rats with experimental autoimmune myasthenia gravis following ＂warming yang and invigorating qi＂ acupuncture therapy.Needles were inserted at acupressure points Shousanli（LI10）,Zusanli（ST36）,Pishu（BL20）,and Shenshu（BL23） once daily for 7 consecutive days.The treatment was repeated after 1 day of rest.We found that area and the integrated optical density of the immunoreactivity for the acetylcholine receptor at the neuromuscular junction of the phrenic nerve was significantly increased following acupuncture treatment.This outcome of the acupuncture therapy was similar to that of the cholinesterase inhibitor pyridostigmine bromide.These findings suggest that ＂warming yang and invigorating qi＂ acupuncture treatment increases acetylcholine receptor expression at the neuromuscular junction in a rat model of autoimmune myasthenia gravis.
基金funded by Bangladesh Agricultural University Research System(BAURES,Bangladesh Agricultural University,Mymensingh through the research project number:2018/597/BAU.Taif University Researchers Supporting Project number(TURSP-2020/120)Taif University,Taif,Saudi Arabia provided the APC of this publication.
文摘Seed priming has proved to be an effective pre-germination seed invigoration technique for different crops to improve seed and seedling performance under different abiotic stresses.In Bangladesh,winter rice is very often exposed to cold waves just after sowing in the nursery bed resulting in poor seed germination and seedling emergence,yellowish and thin seedlings production,and a very low survival rate.Seed priming may mitigate the cold stress during seed germination and seedling emergence and helps in the quality seedling production of winter rice.To evaluate the efficacy of different seed priming techniques in increasing seedling emergence,growth,vigor and survivability of winter rice cultivars under cold stress,a pot experiment was conducted at the Department of Agronomy,Bangladesh Agricultural University during December 2018 to January 2019.The experiment comprised two factors,(A)Winter rice variety namely,(i)BRRI dhan29 and (ii)BRRI dhan36;(B)Seed priming agent namely (i)Control(no priming),(ii)20000 ppm NaCl,(iii)30000 ppm NaCl,(iv)20000 ppm KCl,(v)30000 ppm KCl,(vi)20000 ppm CaCl2,(vii)30000 ppm CaCl2,(viii)50 ppm CuSO4,(ix)75 ppm CuSO_(4),(x)10000 ppm ZnSO4,(xi)15000 ppm ZnSO4,(xii)2 ppm Na2MoO4,(xiii)3 ppm Na2MoO4,(xiv)100 ppm PEG(Polyethylene glycol 4000)and (xv)150 ppm PEG.Seeds were sown on two different dates viz.,1st December and 1st January so that seedlings are exposed to cold stress at different stages.The experiment was laid out in a completely randomized design(CRD)with three replications.Results indicated that(in most of the cases)seed priming has a positive impact on seedling emergence rate(%),root length,shoot length,root shoot ratio,root dry weight,shoot dry weight,seedling dry weight and survival rate(%).Among the priming agents,KCl and CaCl2 performed best;while priming with NaCl and PEG showed no advantages over no priming for both the sowing dates.In general,BRRI dhan36 performed better than BRRI dhan29 in terms of seedling growth because of its higher tolerance to cold stress.But,both the varieties performed similarly in terms of emergence rate and survival rate.Thus,priming is an effective tool to increase seed germination,better seedling growth,and higher seedling survivability of winter rice under cold stress,and KCl(20000 ppm)or CaCl2(20000 ppm)can be considered as a viable priming agent.
文摘The therapeutic effects in treating the intermediate and late rheumatoid arthritis by supplementing the kidney and invigorating blood circulation were observed. In the 43 cases of the treatment group, No. 2 Qu Feng Shi Ling capsules (祛风湿灵胶囊2号) and Fenbid (芬必得) were prescribed, while in the 39 cases of the control group Lei Gong Teng Tablets (雷公藤总甙片) and Fenbid were given. The results showed that the total effective rate in the treatment group was more satisfactory than that in the control (P<0.05 or P<0.01). With less toxic effects, the former could better improve the local swelling and lower the blood viscosity.
基金National Natural Science Foundation Project(No.81573720,81974536)。
文摘Objective:To determine the therapeutic effect of Danggui Shaoyao San with Huangqi on rats with nephrotic syndrome(NS)was discussed,and the scientific connotation of TCM treatment principle was elaborated,so as to provide experimental basis for its clinical application.Methods:The NS rat model was established by iv administration of adriamycin;The rats were divided into model group,Danggui Shaoyao San group,Danggui Shaoyao San with Huangqi group,Huangqi group and positive drug group,with 10 rats in control group;The best dosage ratio of Danggui Shaoyao San and Huangqi was screened by Excel;24 h urine protein was measured by BCA method;The electrolyte level was detected by automatic biochemical analyzer;In serum Urea nitrogen(BUN),Creatinine(SCr),Total cholesterol(TC),Triglyceride(TG),Total protein(TP),Albumin(ALB),Immunoglobulin M(Ig-M)and Immunoglobulin G(Ig-G)were detected by the kit;hematoxylin-eosin staining was used to observe the renal morphology;The Total water content(TBW),Extracellular water content(ECF)and Intracellular water content(ICF)were measured by experimental animal body composition analyzer.Results:Compared with the model group,the urine protein in the modified Astragalus group of Danggui Shaoyao Powder was significantly decreased(P<0.01);Urine electrolytes were significantly decreased and serum electrolytes were significantly increased(P<0.01);Serum BUN,SCR,TC and TG were significantly decreased(P<0.01),while TP,ALB,TBW and ICF were significantly increased(P<0.01);The levels of Ig-M and Ig-G were significantly increased(P<0.01),TBW and ICF were significantly increased,and ECF was significantly decreased(P<0.01);Histopathology showed that the pathological changes of renal tissue were obviously alleviated;The improvement of each index was better than that of Danggui Shaoyao San group and Huangqi group.Conclusion:Danggui Shaoyao San with Huangqi group can significantly improve the edema,proteinuria,blood lipid and immune function of NS rats,and the effect is better than that of Danggui Shaoyao San group and Huangqi group.It has the best therapeutic effect on NS,which indicates that Huangqi plays a key synergistic effect on Danggui Shaoyao San,which verifies the scientific connotation of"Yiqi Huoxue Lishui"in the treatment of NS.
基金National Natural Science Foundation of China(No.81873270)"Six Talent Peaks"High-level Talent Project of Jiangsu Province(No.WSN-012)+2 种基金International Joint Research and Development Project of Nanjing Science and Technology Bureau for Medical and Health Care(No.202002051)PhaseⅢProject of TCM Advantaged Discipline in Nanjing University of Traditional Chinese Medicine(No.ZYX03KF076)"Peak Academic"Talent Project of Jiangsu Hospital of Traditional Chinese Medicine(No.Y2018RC17)。
文摘Chronic kidney disease is a general term for various types of renal diseases characterized by a long course of disease and difficulty in early detection.It is one of the social diseases that need to be solved urgently and its pathogenesis and treatment have always been a hotspot for researchers.Studies have shown that traditional Chinese medicine(TCM)can effectively delay the progress of chronic kidney disease.According to the clinical experience of national famous TCM physicians,based on its pathogenesis of"kidney deficiency as the foundation and poison as the target",chronic kidney disease can be treated by invigorating the kidney and removing toxic.Based on the above background,this paper summarizes the research progress of invigorating the kidney and removing toxic in delaying chronic kidney disease from multiple mechanisms and pathways in modern research.
文摘Recent released Chinese Ski Industry White Paper by Asian International Trade Show for Sporting Equipements and Fashion(ISPO)pointed out that ski industry in China received customers of 12.5 million person times in 2015,and many ski resorts had more than200,000 vistors.Zhao Yinggang,
文摘Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).
文摘Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).
文摘Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).
文摘Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).
文摘Objective: according to statistics, recurrent respiratory tract infection accounts for about 30% of respiratory tract infection, and respiratory tract infection accounts for about 80% of pediatric outpatient service, and it still has a rising trend in recent years. Recurrent respiratory tract infection is a common and frequently-occurring disease in childhood, including upper respiratory tract infection, tonsillitis, acute and chronic pharyngitis, bronchitis, pneumonia and other upper and lower respiratory tract diseases;If the frequency of upper and lower respiratory tract infections in children is too frequent and exceeds a certain number in a year, it can be called recurrent respiratory tract infection. Recurrent respiratory tract singing is more common in children aged 6 months to 6 years old, especially in children aged 1 to 3 years old. With the change of environment, social environment and children's diet structure, the widespread application and nonstandard use of antibiotics and hormones have affected the body's defense function and immune ability, as well as the influence of some factors such as children watching TV, playing mobile phone or playing games for too long, too long, too much learning pressure, etc., which cause children's hyperactivity of liver fire, further aggravate spleen deficiency symptoms, affect the lung, appear upper and lower respiratory tract infections, and further develop into repeated respiratory tract infections;Among them, the syndrome of lung and spleen disorder and liver hyperactivity has become a more common syndrome type of recurrent respiratory tract infection (children's viscera are delicate, form and qi are not sufficient to be susceptible to external pathogens, lung and spleen are insufficient, and heart and liver are surplus).
