Objective To study efficacy and safety of Yiqi Daozhi Formula in the recoveryyof gastrointestinal function after gastric cancer surgery.Methods A total of 67 patients undergoing laparoscopic radical gastrectomy betwee...Objective To study efficacy and safety of Yiqi Daozhi Formula in the recoveryyof gastrointestinal function after gastric cancer surgery.Methods A total of 67 patients undergoing laparoscopic radical gastrectomy between April 2023 and April 2024 were selected and randomly assigned to a treatment group(33 cases)and a control group(34 cases)using a random number method.Both groups received perioperative management based on the Enhanced Recovery After Surgery(ERAS)protocol,with data collected using artificial intelligencepowered wearable electrocardiogram(ECG)recorders and continuous bowel sound auscultation recorders.The treatment group received 100 mL of concentrated Yiqi Daozhi Formula orally from the 1st to 3rd postoperative day,whereas the the control group reveived equal volume of plain water daily over the same period.Key indicators of gastrointestinal recovery encompassed the time to first flatus,bowel sound recovery,semi-liquid diet tolerance,pain scores on the 3rd postoperative day,and length of hospital stay,which were compared between the groups.Additionally,postoperative heart rate variability(HRV)indices,including standard diviation of NN intervals(SDNN),standard deviation of the average NN intervals(SDANN),percentage of difference between adjacent normal R-R intervals exceeding 50 milliseconds(pNN50),low frequency(LF),and high frequency(HF)were evaluated.Inflammatory biomarkers such as high-sensitivity C-reactive protein(hs-CRP),white blood cell(WBC),interleukin(IL)-1β,IL-2,IL-6,tumor necrosis factor-α(TNF-α),interferon-(IFN-)were assessed,alongside the incidence of postoperative complications.Results Compared to the control group,the treatment group exhibited reduced bowel sound recovery time and earlier onset of first flatus(P=0.001).On the 1st postoperative day,the treatment group exhibited decreased levels of hs-CRP,WBC,IL-1β,and IL-2(P<0.001,P<0.05).By the 3rd postoperative day,the treatment group continued to show lower levels of hs-CRP,IL-1β,and IL-2(P<0.001,P<0.05).Furthermore,the treatment group showed higher indices,specifically SDNN,SDANN,pNN50,and LF,on the third postoperative day(P<0.01,P<0.05).Conclusion The application of Yiqi Daozhi Formula post-gastrectomy in patients with gastric cancer surgery is safe,which reduces postoperative inflammatory responses,improves autonomic nervous function,and facilitates early gastrointestinal function recovery.展开更多
The mechanism of antiahock effect of anisodamine (654-2) is still unknown. Experimental shock on rabbits showed that 654-2 had good preventive and therapeutic effect on superior mesenteric artery occlusion shock (SMAO...The mechanism of antiahock effect of anisodamine (654-2) is still unknown. Experimental shock on rabbits showed that 654-2 had good preventive and therapeutic effect on superior mesenteric artery occlusion shock (SMAO shock). It increased survival rate of shock animals and the recovery rate of the animals from shock condition, and at the same time, the amount of exudative fluid loss from the intestinal cavities was significantly decreased. It also exerted good preventive and therapeutic effect展开更多
With a holding capacity of up to 9,100 vehicles(conventional or electric),the Höegh Aurora holds the title of“worlds largest vehicle carrier”.Operated by Norways Höegh Autoliners,the Höegh Aurora was ...With a holding capacity of up to 9,100 vehicles(conventional or electric),the Höegh Aurora holds the title of“worlds largest vehicle carrier”.Operated by Norways Höegh Autoliners,the Höegh Aurora was built by China Merchants Heavy Industry(CMHI)in Jiangsu,China,and made its first voyage last year.Measuring 37.6 meters wide and 199.9 meters long,it is considered the worlds largest Pure Car and Truck Carrier(PCTC)vessel for transporting various types of vehicles,and thanks to strengthened decks and enhanced internal ramp systems(坡道系统),it can carry heavier electric vehicles on all 14 decks,making it future⁃proof.With a cargo capacity of 9,100 vehicles,the first Höegh Aurora class carrier beats the previous worlds largest vehicle carrier by 600 vehicles.展开更多
Case Letter Severe trauma has high morbidity and mortality rates,being the leading cause of death in young adults.Among all traumas,tra ffi c injuries are particularly lethal.^([1-2]) The injury severity score(ISS) ca...Case Letter Severe trauma has high morbidity and mortality rates,being the leading cause of death in young adults.Among all traumas,tra ffi c injuries are particularly lethal.^([1-2]) The injury severity score(ISS) can be used to assess trauma severity,with ISS of<9,9–15,16–24,and≥25 indicating minor,moderate,severe,and critical trauma,respectively.The ISS is correlated with mortality,morbidity,and hospitalization duration after injury.^([3-4]) Here,we report one patient who was admitted to our emergency intensive care unit(EICU) due to traumatic liver rupture and traumatic myocardial infarction complicated with inferior vena cava(IVC) thrombosis.展开更多
With the large-scale deployment of satellite constellations such as Starlink and the rapid advancement of technologies including artificial intelligence (AI) and non-terrestrial networks (NTNs), the integration of hig...With the large-scale deployment of satellite constellations such as Starlink and the rapid advancement of technologies including artificial intelligence (AI) and non-terrestrial networks (NTNs), the integration of high, medium, and low Earth orbit satellite networks with terrestrial networks has become a critical direction for future communication technologies. The objective is to develop a space-terrestrial integrated 6G network that ensures ubiquitous connectivity and seamless services, facilitating intelligent interconnection and collaborative symbiosis among humans, machines, and objects. This integration has become a central focus of global technological innovation.展开更多
Objective To examine the expression of follistatinlike protein 1(FSTL1)in the peripheral blood and intestinal mucosa tissues of ulcerative colitis(UC)patients and analyze the correlation between its expression and the...Objective To examine the expression of follistatinlike protein 1(FSTL1)in the peripheral blood and intestinal mucosa tissues of ulcerative colitis(UC)patients and analyze the correlation between its expression and the activity of UC.Methods From October 2010 to J une2012,sixty patients with UC were collected.From展开更多
Endoscopic submucosal dissection(ESD)is the standard treatment for early-stage gastric cancer,but the large post-operative ulcers caused by ESD often lead to serious side effects.Post-ESD mu-cosal repair materials pro...Endoscopic submucosal dissection(ESD)is the standard treatment for early-stage gastric cancer,but the large post-operative ulcers caused by ESD often lead to serious side effects.Post-ESD mu-cosal repair materials provide a new option for the treatment of post-ESD ulcers.In this study,we developed a polyurethane/small intestinal submucosa(PU/SIS)hydrogel and investigated its effi-cacy for accelerating ESD-induced ulcer healing in a canine model.PU/SIS hydrogel possessed great biocompatibility and distinctive pH-sensitive swelling properties and protected GES-1 cells from acid attack through forming a dense film in acidic conditions in vitro.Besides,PU/SIS gels present a strong bio-adhesion to gastric tissues under acidic conditions,thus ensuring the reten-tion time of PU/SIS gels in vivo.In a canine model,PU/SIS hydrogel was easily delivered via endoscopy and adhered to the ulcer sites.PU/SIS hydrogel accelerated gastric ulcer healing at an early stage with more epithelium regeneration and slight inflammation.Our findings reveal PU/SIS hydrogel is a promising and attractive candidate for ESD-induced ulcer repair.展开更多
The vehicles and pedestrians ranging is one of the basic functions of advanced driving assistance system.However,most of the ranging systems can only work on workstations with high computing power.To solve this proble...The vehicles and pedestrians ranging is one of the basic functions of advanced driving assistance system.However,most of the ranging systems can only work on workstations with high computing power.To solve this problem,a lightweight algorithm is proposed to be packaged into Android application package,and be installed in Android smartphones for vehicles and pedestrians ranging.The proposed ranging system is based on the images obtained by smartphone’s monocular camera.To achieve real-time ranging,an 8-bit integer(int8)quantization algorithm is proposed to accelerate the inference of convolutional neural networks.To increase the detection precision,a zoom-in algorithm is further proposed to detect small targets in the distance.After having detected the 2D bounding boxes of vehicles and pedestrians,a pinhole ranging method is applied to estimate the distance.In order to verify the proposed algorithm,the mean average precision(mAP)and the frame per second(FPS)are first tested by using COCO dataset on Huawei P40Pro,then,the ranging precision on the real road.The experimental results show that this algorithm can successfully perform real-time ranging(15 FPS)with high precision(34.8 mAP)onto the tested smartphones.Finally,a possible mobile application based on the ranging algorithm,i.e.,distance keeping warning,is also provided.展开更多
文摘Objective To study efficacy and safety of Yiqi Daozhi Formula in the recoveryyof gastrointestinal function after gastric cancer surgery.Methods A total of 67 patients undergoing laparoscopic radical gastrectomy between April 2023 and April 2024 were selected and randomly assigned to a treatment group(33 cases)and a control group(34 cases)using a random number method.Both groups received perioperative management based on the Enhanced Recovery After Surgery(ERAS)protocol,with data collected using artificial intelligencepowered wearable electrocardiogram(ECG)recorders and continuous bowel sound auscultation recorders.The treatment group received 100 mL of concentrated Yiqi Daozhi Formula orally from the 1st to 3rd postoperative day,whereas the the control group reveived equal volume of plain water daily over the same period.Key indicators of gastrointestinal recovery encompassed the time to first flatus,bowel sound recovery,semi-liquid diet tolerance,pain scores on the 3rd postoperative day,and length of hospital stay,which were compared between the groups.Additionally,postoperative heart rate variability(HRV)indices,including standard diviation of NN intervals(SDNN),standard deviation of the average NN intervals(SDANN),percentage of difference between adjacent normal R-R intervals exceeding 50 milliseconds(pNN50),low frequency(LF),and high frequency(HF)were evaluated.Inflammatory biomarkers such as high-sensitivity C-reactive protein(hs-CRP),white blood cell(WBC),interleukin(IL)-1β,IL-2,IL-6,tumor necrosis factor-α(TNF-α),interferon-(IFN-)were assessed,alongside the incidence of postoperative complications.Results Compared to the control group,the treatment group exhibited reduced bowel sound recovery time and earlier onset of first flatus(P=0.001).On the 1st postoperative day,the treatment group exhibited decreased levels of hs-CRP,WBC,IL-1β,and IL-2(P<0.001,P<0.05).By the 3rd postoperative day,the treatment group continued to show lower levels of hs-CRP,IL-1β,and IL-2(P<0.001,P<0.05).Furthermore,the treatment group showed higher indices,specifically SDNN,SDANN,pNN50,and LF,on the third postoperative day(P<0.01,P<0.05).Conclusion The application of Yiqi Daozhi Formula post-gastrectomy in patients with gastric cancer surgery is safe,which reduces postoperative inflammatory responses,improves autonomic nervous function,and facilitates early gastrointestinal function recovery.
文摘The mechanism of antiahock effect of anisodamine (654-2) is still unknown. Experimental shock on rabbits showed that 654-2 had good preventive and therapeutic effect on superior mesenteric artery occlusion shock (SMAO shock). It increased survival rate of shock animals and the recovery rate of the animals from shock condition, and at the same time, the amount of exudative fluid loss from the intestinal cavities was significantly decreased. It also exerted good preventive and therapeutic effect
文摘With a holding capacity of up to 9,100 vehicles(conventional or electric),the Höegh Aurora holds the title of“worlds largest vehicle carrier”.Operated by Norways Höegh Autoliners,the Höegh Aurora was built by China Merchants Heavy Industry(CMHI)in Jiangsu,China,and made its first voyage last year.Measuring 37.6 meters wide and 199.9 meters long,it is considered the worlds largest Pure Car and Truck Carrier(PCTC)vessel for transporting various types of vehicles,and thanks to strengthened decks and enhanced internal ramp systems(坡道系统),it can carry heavier electric vehicles on all 14 decks,making it future⁃proof.With a cargo capacity of 9,100 vehicles,the first Höegh Aurora class carrier beats the previous worlds largest vehicle carrier by 600 vehicles.
文摘Case Letter Severe trauma has high morbidity and mortality rates,being the leading cause of death in young adults.Among all traumas,tra ffi c injuries are particularly lethal.^([1-2]) The injury severity score(ISS) can be used to assess trauma severity,with ISS of<9,9–15,16–24,and≥25 indicating minor,moderate,severe,and critical trauma,respectively.The ISS is correlated with mortality,morbidity,and hospitalization duration after injury.^([3-4]) Here,we report one patient who was admitted to our emergency intensive care unit(EICU) due to traumatic liver rupture and traumatic myocardial infarction complicated with inferior vena cava(IVC) thrombosis.
文摘With the large-scale deployment of satellite constellations such as Starlink and the rapid advancement of technologies including artificial intelligence (AI) and non-terrestrial networks (NTNs), the integration of high, medium, and low Earth orbit satellite networks with terrestrial networks has become a critical direction for future communication technologies. The objective is to develop a space-terrestrial integrated 6G network that ensures ubiquitous connectivity and seamless services, facilitating intelligent interconnection and collaborative symbiosis among humans, machines, and objects. This integration has become a central focus of global technological innovation.
文摘Objective To examine the expression of follistatinlike protein 1(FSTL1)in the peripheral blood and intestinal mucosa tissues of ulcerative colitis(UC)patients and analyze the correlation between its expression and the activity of UC.Methods From October 2010 to J une2012,sixty patients with UC were collected.From
基金This work was supported by The National Key R&D Program of China(2017YFC1104702)Sichuan Science and Technology Program(2019JDRC0020)the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYJC18002).
文摘Endoscopic submucosal dissection(ESD)is the standard treatment for early-stage gastric cancer,but the large post-operative ulcers caused by ESD often lead to serious side effects.Post-ESD mu-cosal repair materials provide a new option for the treatment of post-ESD ulcers.In this study,we developed a polyurethane/small intestinal submucosa(PU/SIS)hydrogel and investigated its effi-cacy for accelerating ESD-induced ulcer healing in a canine model.PU/SIS hydrogel possessed great biocompatibility and distinctive pH-sensitive swelling properties and protected GES-1 cells from acid attack through forming a dense film in acidic conditions in vitro.Besides,PU/SIS gels present a strong bio-adhesion to gastric tissues under acidic conditions,thus ensuring the reten-tion time of PU/SIS gels in vivo.In a canine model,PU/SIS hydrogel was easily delivered via endoscopy and adhered to the ulcer sites.PU/SIS hydrogel accelerated gastric ulcer healing at an early stage with more epithelium regeneration and slight inflammation.Our findings reveal PU/SIS hydrogel is a promising and attractive candidate for ESD-induced ulcer repair.
基金the RoboCar Project for Internationalization of RTI Projects within the Frame of the Austrian Research Promotion Agency(No.861000)。
文摘The vehicles and pedestrians ranging is one of the basic functions of advanced driving assistance system.However,most of the ranging systems can only work on workstations with high computing power.To solve this problem,a lightweight algorithm is proposed to be packaged into Android application package,and be installed in Android smartphones for vehicles and pedestrians ranging.The proposed ranging system is based on the images obtained by smartphone’s monocular camera.To achieve real-time ranging,an 8-bit integer(int8)quantization algorithm is proposed to accelerate the inference of convolutional neural networks.To increase the detection precision,a zoom-in algorithm is further proposed to detect small targets in the distance.After having detected the 2D bounding boxes of vehicles and pedestrians,a pinhole ranging method is applied to estimate the distance.In order to verify the proposed algorithm,the mean average precision(mAP)and the frame per second(FPS)are first tested by using COCO dataset on Huawei P40Pro,then,the ranging precision on the real road.The experimental results show that this algorithm can successfully perform real-time ranging(15 FPS)with high precision(34.8 mAP)onto the tested smartphones.Finally,a possible mobile application based on the ranging algorithm,i.e.,distance keeping warning,is also provided.
