Current immunological research covers a broad spectrum of areas,including host defense mechanisms,inflammatory signaling pathways,immune regulation,immunometabolism,and therapeutic interventions,with an increasing foc...Current immunological research covers a broad spectrum of areas,including host defense mechanisms,inflammatory signaling pathways,immune regulation,immunometabolism,and therapeutic interventions,with an increasing focus on systems immunology and multi-omics,nextgeneration cell therapies and biologics,and disease microenvironment analyses.This special issue comprises one review,eight original articles,and a letter covering diverse topics,including opioidmediated immunomodulation,wound healing,osteoarthritis pathogenesis,neutrophil extracellular trap formation,vector control strategies,the genetic basis of the gut-skin axis,hepatitis C vaccine development,single-cell immune profiling in viral infection,neutralizing antibody discovery,and the association between vitamin D levels and cancer risk in psoriasis patients.展开更多
Peyronie's disease(PD)is a challenging condition that significantly impacts male sexual health,often leading to penile curvature,pain,and erectile dysfunction.Treatment options range from conservative pharmacologi...Peyronie's disease(PD)is a challenging condition that significantly impacts male sexual health,often leading to penile curvature,pain,and erectile dysfunction.Treatment options range from conservative pharmacologic approaches to more invasive surgical interventions,with collagenase clostridium histolyticum(CCH)being the only U.S.Food and Drug Administration(FDA)-approved intralesional therapy.However,optimizing treatment strategies to enhance efficacy while minimizing patient burden remains an area of ongoing investigation.^(1,2)展开更多
文摘Current immunological research covers a broad spectrum of areas,including host defense mechanisms,inflammatory signaling pathways,immune regulation,immunometabolism,and therapeutic interventions,with an increasing focus on systems immunology and multi-omics,nextgeneration cell therapies and biologics,and disease microenvironment analyses.This special issue comprises one review,eight original articles,and a letter covering diverse topics,including opioidmediated immunomodulation,wound healing,osteoarthritis pathogenesis,neutrophil extracellular trap formation,vector control strategies,the genetic basis of the gut-skin axis,hepatitis C vaccine development,single-cell immune profiling in viral infection,neutralizing antibody discovery,and the association between vitamin D levels and cancer risk in psoriasis patients.
文摘Peyronie's disease(PD)is a challenging condition that significantly impacts male sexual health,often leading to penile curvature,pain,and erectile dysfunction.Treatment options range from conservative pharmacologic approaches to more invasive surgical interventions,with collagenase clostridium histolyticum(CCH)being the only U.S.Food and Drug Administration(FDA)-approved intralesional therapy.However,optimizing treatment strategies to enhance efficacy while minimizing patient burden remains an area of ongoing investigation.^(1,2)
