According to the analysis, there are still many problems in our foreign language teaching. To improve students' English acquisition, foreign language teaching should follow the law of SLA based on the function of ...According to the analysis, there are still many problems in our foreign language teaching. To improve students' English acquisition, foreign language teaching should follow the law of SLA based on the function of internalized grammar.展开更多
Stigma and discrimination because of epilepsy, leprosy and HIV/aids has decreased over the years, but this has not happened as regards mental illness. One aspect of the stigma issue is what has been described as self-...Stigma and discrimination because of epilepsy, leprosy and HIV/aids has decreased over the years, but this has not happened as regards mental illness. One aspect of the stigma issue is what has been described as self-stigmatization, the way the mentally ill look at themselves. The aim of this study was to illuminate the self-perception of mentally ill persons in a Swedish setting. An internationally well established questionnaire, Internalized Stigma of Mental Illness scale (ISMI) was used to investigate two samples of out-patients from northern Sweden (N = 260). Fifty two percent reported “minimum stigma”, 35% “mild” and 13% “moderate/severe” stigma. As many as 58% agreed to the statement “I am embarrassed or ashamed that I have a mental illness”. The levels of internalized stigma are rather high, but somewhat lower than reported from some other European and an Iranian study using the same methodology. In spite of several campaigns aimed at reducing the stigma and discrimination because of mental illness in Sweden, still the experience of self stigma is rather high. There is an urgent need to further developed anti-stigma strategies.展开更多
Purpose: There is extensive evidence regarding the relationship between HIV related stigma and disclosure;however, the influence of depression in this relationship is not well understood, and thus is the focus of our ...Purpose: There is extensive evidence regarding the relationship between HIV related stigma and disclosure;however, the influence of depression in this relationship is not well understood, and thus is the focus of our analysis. Methods: Baseline data from a prospective longitudinal cohort of 798 HIV patients starting ART in Kampala, Uganda were examined. A staged-approach regression analysis was used to examine variables associated with HIV disclosure to most people (general disclosure) and disclosure to primary sex partner. Internalized HIV stigma plus demographic and background covariates were first entered into the model;the binary indicator of clinical depression was added on step two, followed by the addition of the interaction of stigma and depression in step three. Separate analyses were conducted for each of the two disclosure outcomes. Results: 39% indicated that they kept their HIV status as a secret from most people, while 19% of respondents with a regular sex partner had not disclosed their HIV status to the partner. In bivariate analysis, respondents who preferred to keep their HIV status as a secret from most people had higher internalized HIV stigma (p < 0.001) and depression (p < 0.01), and were more likely to be clinically depressed (p < 0.01) compared with others in the sample. Similarly, participants who had not disclosed their HIV status to their main sex partner had higher internalized HIV stigma (p < 0.01) and depression (p < 0.05), and were more likely to be clinically depressed (p < 0.01) compared with those who had informed their partner of their HIV status. The regression analysis revealed that internalized HIV stigma was strongly negatively correlated with disclosure to primary partner, while depression was not associated. In the regression analysis for general disclosure, both stigma and depression were negatively correlated with disclosure when the interaction term was included in the model. Further analysis showed that internalized HIV stigma was more strongly associated with general disclosure among participants who were not depressed. Conclusions: Although there was clearly a strong and consistent association between internalized HIV stigma and depression symptoms, the strong association between internalized HIV stigma and general disclosure among respondents who were not depressed indicated that HIV stigma was in itself remained a strong barrier to HIV disclosure. Therefore, interventions to reduce internalized HIV stigma may aid in efforts to decrease secondary transmission of HIV.展开更多
Background:Erzhu Erchen decoction(EZECD),which is based on Erchen decoction and enhanced with Atractylodes lancea and Atractylodes macrocephala,is widely used for the treatment of dampness and heat(The clinical manife...Background:Erzhu Erchen decoction(EZECD),which is based on Erchen decoction and enhanced with Atractylodes lancea and Atractylodes macrocephala,is widely used for the treatment of dampness and heat(The clinical manifestations of Western medicine include thirst,inability to drink more,diarrhea,yellow urine,red tongue,et al.)internalized disease.Nevertheless,the mechanism of EZECD on damp-heat internalized Type 2 diabetes(T2D)remains unknown.We employed data mining,pharmacology databases and experimental verification to study how EZECD treats damp-heat internalized T2D.Methods:The main compounds or genes of EZECD and damp-heat internalized T2D were obtained from the pharmacology databases.Succeeding,the overlapped targets of EZECD and damp-heat internalized T2D were performed by the Gene Ontology,kyoto encyclopedia of genes and genomes analysis.And the compound-disease targets-pathway network were constructed to obtain the hub compound.Moreover,the hub genes and core related pathways were mined with weighted gene co-expression network analysis based on Gene Expression Omnibus database,the capability of hub compound and genes was valid in AutoDock 1.5.7.Furthermore,and violin plot and gene set enrichment analysis were performed to explore the role of hub genes in damp-heat internalized T2D.Finally,the interactions of hub compound and genes were explored using Comparative Toxicogenomics Database and quantitative polymerase chain reaction.Results:First,herb-compounds-genes-disease network illustrated that the hub compound of EZECD for damp-heat internalized T2D could be quercetin.Consistently,the hub genes were CASP8,CCL2,and AHR according to weighted gene co-expression network analysis.Molecular docking showed that quercetin could bind with the hub genes.Further,gene set enrichment analysis and Gene Ontology represented that CASP8,or CCL2,is negatively involved in insulin secretion response to the TNF or lipopolysaccharide process,and AHR or CCL2 positively regulated lipid and atherosclerosis,and/or including NOD-like receptor signaling pathway,and TNF signaling pathway.Ultimately,the quantitative polymerase chain reaction and western blotting analysis showed that quercetin could down-regulated the mRNA and protein experssion of CASP8,CCL2,and AHR.It was consistent with the results in Comparative Toxicogenomics Database databases.Conclusion:These results demonstrated quercetin could inhibit the expression of CASP8,CCL2,AHR in damp-heat internalized T2D,which improves insulin secretion and inhibits lipid and atherosclerosis,as well as/or including NOD-like receptor signaling pathway,and TNF signaling pathway,suggesting that EZECD may be more effective to treat damp-heat internalized T2D.展开更多
Objectives: Stigma and discrimination because of mental illness is still prevalent even in high-income countries where a lot of emphasis has been given to anti-stigma activities and measures to reduce the marginalizat...Objectives: Stigma and discrimination because of mental illness is still prevalent even in high-income countries where a lot of emphasis has been given to anti-stigma activities and measures to reduce the marginalization of these persons. One aspect of the stigma issue is the self-stigmatization that persons suffering from mental illness are experiencing. In this study two different societies have been compared as regards internalized stigma of mental illness. Methods: A widely used questionnaire was used by the Internalized Stigma of Mental Illness scale (ISMI). One sample of psychiatric patients from Sweden (N = 163) and from Iran (N = 138) is compared. Results: The Swedish sample generally reports lower levels of experienced stigma except for items covering selfblame and feelings of alienation. Conclusions: There are reasons to consider the aspect of self-stigmatization when working with mentally ill persons even in high income countries with well developed mental health services.展开更多
Caveolae and non-caveolar lipid rafts are two types of membrane lipid microdomains that play important roles in insulin-stimulated glucose uptake in adipocytes. In order to ascertain their specific functions in this p...Caveolae and non-caveolar lipid rafts are two types of membrane lipid microdomains that play important roles in insulin-stimulated glucose uptake in adipocytes. In order to ascertain their specific functions in this process, caveolae were ablated by caveolin-1 RNA interference. In Cav-1 RNAi adipocytes, neither insulin-stimulated glucose uptake nor Glut-4 （glucose transporter 4） translocation to membrane lipid microdomains was affected by the ablation of caveolae. With a modified sucrose density gradient, caveolae and non-caveolar lipid rafts could be separated. In the wild-type 3T3- L l adipocytes, Glut-4 was found to be translocated into both caveolae and non-caveolar lipid rafts. However, in Cav1 RNAi adipocytes, Glut-4 was localized predominantly in non-caveolar lipid rafts. After the removal of insulin, caveolaelocalized Glut-4 was internalized faster than non-caveolar lipid raft-associated Glut-4. The internalization of Glut-4 from plasma membrane was significantly decreased in Cav-1 RNAi adipocytes. These results suggest that insulin-stimulated Glut-4 translocation and glucose uptake are caveolae-independent events. Caveolae play a role in the internalization of Glut-4 from plasma membrane after the removal of insulin.展开更多
Although mental health symptoms in children and adolescents are shown to predict young adult mental health outcomes, long-term prospective studies of childhood cohorts are few. The aim of the present study was to anal...Although mental health symptoms in children and adolescents are shown to predict young adult mental health outcomes, long-term prospective studies of childhood cohorts are few. The aim of the present study was to analyze the prospective importance of internalized mental health symptoms in adolescence for internalized symptoms in adulthood. Methods: A community-based prospective longitudinal cohort provided information by questionnaire about psychological status at age 16 and 43 (n=1010, representing 94.3% of those still alive). Socio-demographic variables which were indicative of possible childhood adversity (parental class, absence, illness, unemployment, relationship, crowding, number of moves) were treated as confounders and controlled for in ordinal regression. Results: For both women and men, internalizing mental health symptoms reported at 16 significantly predicted the same outcome at 43 years, after controlling for previous adverse environmental conditions (OR =1.2 for women, 1.3 for men). Conclusion: In this representative cohort studied over 27 years with excellent retention rates, the occurrence of self-reported worry, panic and sadness in mid-adolescence significantly increased the likelihood of similar states in middle adulthood.展开更多
基于国际比较的地方空间规划的范围和工具研究An International Comparison of the Scope and Instruments of Local Spatial Planning源自:The TownPlanning Review,2024,95(2):197-217作者:MaciejJNowak,StefanieDühr,Sergio Pe&...基于国际比较的地方空间规划的范围和工具研究An International Comparison of the Scope and Instruments of Local Spatial Planning源自:The TownPlanning Review,2024,95(2):197-217作者:MaciejJNowak,StefanieDühr,Sergio Peña,et al.推荐:申明锐,南京大学建筑与城市规划学院。shenmingr@nju.edu.cn.展开更多
This article investigates the robust current tracking control problem of three-phase grid-connected inverters with LCL filter under external disturbance by a dynamic state feedback control method.First,this paper cons...This article investigates the robust current tracking control problem of three-phase grid-connected inverters with LCL filter under external disturbance by a dynamic state feedback control method.First,this paper constructs an internal model to learn the information of the states and input of the grid-connected inverter under steady state.Second,by utilizing the internal model principle,the paper turns the tracking control problem into the robust stabilization control problem based on some appropriate coordinate transformations.Then,The paper designs a dynamics state feedback control law to deal with this robust stabilization problem,and thus the solution of the robust current tracking control problem of three-phase grid-connected inverters can be obtained.This control method can ensure the asymptotic stability of the closedloop system.Finally,the paper illustrates the effectiveness of the proposed control approach through several groups of simulations,and compares it with the feedforward control method to verify the robustness of the proposed control method to uncertain parameters.展开更多
Analysis Method of ^(131)I Activity in Carbon Cartridge and Internal Dose Assessment for Nuclear Medicine Workers.Shuo Wang1,Fei Tuo1,Jian-feng Zhang1,Xiao-liang Li1,Bao-lu Yang1,Qiang Zhou1,Ze-shu Li1,Shu-ying Kong1,...Analysis Method of ^(131)I Activity in Carbon Cartridge and Internal Dose Assessment for Nuclear Medicine Workers.Shuo Wang1,Fei Tuo1,Jian-feng Zhang1,Xiao-liang Li1,Bao-lu Yang1,Qiang Zhou1,Ze-shu Li1,Shu-ying Kong1,and Wei-hao Qin1(1.National Institute for Radiological Protection,Chinese Center for Disease Control and Prevention,Beijing,100088,China.)展开更多
Journal of Iron and Steel Research International(中文刊名:钢铁研究学报(英文版),下文简称JISRI)是由中国钢铁工业协会主管、中国钢研科技集团有限公司主办的冶金领域学术期刊(CN 11-3678/TF,ISSN 1006-706X)。JISRI于1994年创刊,月...Journal of Iron and Steel Research International(中文刊名:钢铁研究学报(英文版),下文简称JISRI)是由中国钢铁工业协会主管、中国钢研科技集团有限公司主办的冶金领域学术期刊(CN 11-3678/TF,ISSN 1006-706X)。JISRI于1994年创刊,月刊,主编为赵栋梁教授和Hongbiao Dong教授。展开更多
The International Radiation Symposium(IRS) is a quadrennial symposium of the International Radiation Commission(IRC), one of the 11 commissions under the International Association of Meteorology and Atmospheric Scienc...The International Radiation Symposium(IRS) is a quadrennial symposium of the International Radiation Commission(IRC), one of the 11 commissions under the International Association of Meteorology and Atmospheric Sciences(IAMAS).The role of the IRC is to promote fundamental research in atmospheric radiation and its applications to practical problems.展开更多
The year 2025 witnessed the profound evolution of the international landscape,characterized by intensified major-power rivalry,protracted geopolitical conflicts,erosion of multilateral mechanisms,and increasingly obso...The year 2025 witnessed the profound evolution of the international landscape,characterized by intensified major-power rivalry,protracted geopolitical conflicts,erosion of multilateral mechanisms,and increasingly obsolete international rules.The old order is dying,and the new one is yet to be born.The future trajectory of the world hinges largely on whether nations,particularly major powers,can manage differences and seek cooperation through effective communication amidst the complex and volatile environment.展开更多
In 2025,the global landscape has undergone profound transformations,with the international architecture continuing to adjust.The fragility and uncertainty of international security have become increasingly pronounced....In 2025,the global landscape has undergone profound transformations,with the international architecture continuing to adjust.The fragility and uncertainty of international security have become increasingly pronounced.Frequent regional conflicts and political instability have triggered a deep sense of insecurity,while latent risks have emerged one after another,exacerbating turbulence and disorder.Some countries still cling to a zero-sum mindset,selectively applying or discarding international rules based on their interests.Hegemonism and unilateralism have severely undermined the UN-centered international system,leading to a resurgence of geopolitical rivalry and intensified bloc confrontation.The provision of global public goods remains severely inadequate,security risks continue to accumulate,and the journey toward effective global security governance remains long and challenging.展开更多
GLOBAL GOVERNANCE AS AN INSTRUMENT FOR TRANSFORMING CHAOS INTO ORDERLY MULTIPOLARITY The current global geopolitical situation,marked by instability,the erosion of the post-WWII international order and the weakening o...GLOBAL GOVERNANCE AS AN INSTRUMENT FOR TRANSFORMING CHAOS INTO ORDERLY MULTIPOLARITY The current global geopolitical situation,marked by instability,the erosion of the post-WWII international order and the weakening of US unipolar dominance,requires joint efforts by major international actors and the wider international community to establish a functional international order for the twenty-first century.展开更多
At the IEC,Chinese experts have been contributing their expertise to international standardization.As one of them,Ma Dejun has grown from an inexperienced explorer in the field of standardization into a distinguished ...At the IEC,Chinese experts have been contributing their expertise to international standardization.As one of them,Ma Dejun has grown from an inexperienced explorer in the field of standardization into a distinguished expert driving the development of international standards in key sectors over the past 35 years.He was presented with the 2025 Lord Kelvin Award at the 89th IEC General Meeting held in New Delhi,India,in September 2025.Thus,he became the first Chinese expert to receive the highest honor bestowed by the IEC.In an exclusive interview with Ma Dejun,he reviewed his original aspiration behind his decades-long journey in international standardization,shared his experience and insights on promoting international standards,and looked forward to China's future role on the international standardiz ation stage.展开更多
I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single inve...I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single investigator or an isolated team.My advice is intended for early-career scientists.The product of the collaboration may be high-impact research publications,enhanced geophysical monitoring capabilities in a foreign country,or an advanced training course.Choosing the right international partner is the most important step.Keeping an open mind and being receptive to suggestions to modify the initial concept is critical.Other key steps include having a mutually agreed upon plan with achievable goals and well-defined expected outcomes.International cooperation is a richly rewarding experience that accelerates progress in the Earth Sciences.展开更多
The China Expo Forum for International Cooperation(CEFCO)2026 was held in Wuhan,Hubei Province,China,on January 22.The opening ceremony was attended by Li Qing Shuang,Vice President of the China Council for the Promot...The China Expo Forum for International Cooperation(CEFCO)2026 was held in Wuhan,Hubei Province,China,on January 22.The opening ceremony was attended by Li Qing Shuang,Vice President of the China Council for the Promotion of International Trade(CCPIT);Zhu Yuji,Deputy Secretary of the Hubei Provincial Committee of the Communist Party of China;Sheng Yue Chun,Member of the Standing Committee of the Hubei Provincial Committee of the Communist Party of China and Secretary of the Wuhan Municipal Committee;Punita Bhansal,President of the Global Association of the Exhibition Industry(UFI);Marsha Flanagan,President and CEO of the International Association of Exhibitions and Events(IAEE);Vincent Polito,CEO of the Society of Independent Show Organizers(SISO);and Leonie Ashford,Board Member of the International Congress and Convention Association(ICCA).展开更多
The Chinese Journal of Chemical Engineering is the official journal of The Chemical Industry and Engineering Society of China and published by the Chemical Industry Press Co.,Ltd.The aim of the journal is to develop t...The Chinese Journal of Chemical Engineering is the official journal of The Chemical Industry and Engineering Society of China and published by the Chemical Industry Press Co.,Ltd.The aim of the journal is to develop the international exchange of scientific and technical information in the field of chemical engineering.Submission of Papers All papers will be submitted on line.展开更多
文摘According to the analysis, there are still many problems in our foreign language teaching. To improve students' English acquisition, foreign language teaching should follow the law of SLA based on the function of internalized grammar.
文摘Stigma and discrimination because of epilepsy, leprosy and HIV/aids has decreased over the years, but this has not happened as regards mental illness. One aspect of the stigma issue is what has been described as self-stigmatization, the way the mentally ill look at themselves. The aim of this study was to illuminate the self-perception of mentally ill persons in a Swedish setting. An internationally well established questionnaire, Internalized Stigma of Mental Illness scale (ISMI) was used to investigate two samples of out-patients from northern Sweden (N = 260). Fifty two percent reported “minimum stigma”, 35% “mild” and 13% “moderate/severe” stigma. As many as 58% agreed to the statement “I am embarrassed or ashamed that I have a mental illness”. The levels of internalized stigma are rather high, but somewhat lower than reported from some other European and an Iranian study using the same methodology. In spite of several campaigns aimed at reducing the stigma and discrimination because of mental illness in Sweden, still the experience of self stigma is rather high. There is an urgent need to further developed anti-stigma strategies.
文摘Purpose: There is extensive evidence regarding the relationship between HIV related stigma and disclosure;however, the influence of depression in this relationship is not well understood, and thus is the focus of our analysis. Methods: Baseline data from a prospective longitudinal cohort of 798 HIV patients starting ART in Kampala, Uganda were examined. A staged-approach regression analysis was used to examine variables associated with HIV disclosure to most people (general disclosure) and disclosure to primary sex partner. Internalized HIV stigma plus demographic and background covariates were first entered into the model;the binary indicator of clinical depression was added on step two, followed by the addition of the interaction of stigma and depression in step three. Separate analyses were conducted for each of the two disclosure outcomes. Results: 39% indicated that they kept their HIV status as a secret from most people, while 19% of respondents with a regular sex partner had not disclosed their HIV status to the partner. In bivariate analysis, respondents who preferred to keep their HIV status as a secret from most people had higher internalized HIV stigma (p < 0.001) and depression (p < 0.01), and were more likely to be clinically depressed (p < 0.01) compared with others in the sample. Similarly, participants who had not disclosed their HIV status to their main sex partner had higher internalized HIV stigma (p < 0.01) and depression (p < 0.05), and were more likely to be clinically depressed (p < 0.01) compared with those who had informed their partner of their HIV status. The regression analysis revealed that internalized HIV stigma was strongly negatively correlated with disclosure to primary partner, while depression was not associated. In the regression analysis for general disclosure, both stigma and depression were negatively correlated with disclosure when the interaction term was included in the model. Further analysis showed that internalized HIV stigma was more strongly associated with general disclosure among participants who were not depressed. Conclusions: Although there was clearly a strong and consistent association between internalized HIV stigma and depression symptoms, the strong association between internalized HIV stigma and general disclosure among respondents who were not depressed indicated that HIV stigma was in itself remained a strong barrier to HIV disclosure. Therefore, interventions to reduce internalized HIV stigma may aid in efforts to decrease secondary transmission of HIV.
基金supported by a grant from Hubei Key Laboratory of Diabetes and Angiopathy Program of Hubei University of Science and Technology(2020XZ10)Project of Education Commission of Hubei Province(B2022192).
文摘Background:Erzhu Erchen decoction(EZECD),which is based on Erchen decoction and enhanced with Atractylodes lancea and Atractylodes macrocephala,is widely used for the treatment of dampness and heat(The clinical manifestations of Western medicine include thirst,inability to drink more,diarrhea,yellow urine,red tongue,et al.)internalized disease.Nevertheless,the mechanism of EZECD on damp-heat internalized Type 2 diabetes(T2D)remains unknown.We employed data mining,pharmacology databases and experimental verification to study how EZECD treats damp-heat internalized T2D.Methods:The main compounds or genes of EZECD and damp-heat internalized T2D were obtained from the pharmacology databases.Succeeding,the overlapped targets of EZECD and damp-heat internalized T2D were performed by the Gene Ontology,kyoto encyclopedia of genes and genomes analysis.And the compound-disease targets-pathway network were constructed to obtain the hub compound.Moreover,the hub genes and core related pathways were mined with weighted gene co-expression network analysis based on Gene Expression Omnibus database,the capability of hub compound and genes was valid in AutoDock 1.5.7.Furthermore,and violin plot and gene set enrichment analysis were performed to explore the role of hub genes in damp-heat internalized T2D.Finally,the interactions of hub compound and genes were explored using Comparative Toxicogenomics Database and quantitative polymerase chain reaction.Results:First,herb-compounds-genes-disease network illustrated that the hub compound of EZECD for damp-heat internalized T2D could be quercetin.Consistently,the hub genes were CASP8,CCL2,and AHR according to weighted gene co-expression network analysis.Molecular docking showed that quercetin could bind with the hub genes.Further,gene set enrichment analysis and Gene Ontology represented that CASP8,or CCL2,is negatively involved in insulin secretion response to the TNF or lipopolysaccharide process,and AHR or CCL2 positively regulated lipid and atherosclerosis,and/or including NOD-like receptor signaling pathway,and TNF signaling pathway.Ultimately,the quantitative polymerase chain reaction and western blotting analysis showed that quercetin could down-regulated the mRNA and protein experssion of CASP8,CCL2,and AHR.It was consistent with the results in Comparative Toxicogenomics Database databases.Conclusion:These results demonstrated quercetin could inhibit the expression of CASP8,CCL2,AHR in damp-heat internalized T2D,which improves insulin secretion and inhibits lipid and atherosclerosis,as well as/or including NOD-like receptor signaling pathway,and TNF signaling pathway,suggesting that EZECD may be more effective to treat damp-heat internalized T2D.
文摘Objectives: Stigma and discrimination because of mental illness is still prevalent even in high-income countries where a lot of emphasis has been given to anti-stigma activities and measures to reduce the marginalization of these persons. One aspect of the stigma issue is the self-stigmatization that persons suffering from mental illness are experiencing. In this study two different societies have been compared as regards internalized stigma of mental illness. Methods: A widely used questionnaire was used by the Internalized Stigma of Mental Illness scale (ISMI). One sample of psychiatric patients from Sweden (N = 163) and from Iran (N = 138) is compared. Results: The Swedish sample generally reports lower levels of experienced stigma except for items covering selfblame and feelings of alienation. Conclusions: There are reasons to consider the aspect of self-stigmatization when working with mentally ill persons even in high income countries with well developed mental health services.
文摘Caveolae and non-caveolar lipid rafts are two types of membrane lipid microdomains that play important roles in insulin-stimulated glucose uptake in adipocytes. In order to ascertain their specific functions in this process, caveolae were ablated by caveolin-1 RNA interference. In Cav-1 RNAi adipocytes, neither insulin-stimulated glucose uptake nor Glut-4 （glucose transporter 4） translocation to membrane lipid microdomains was affected by the ablation of caveolae. With a modified sucrose density gradient, caveolae and non-caveolar lipid rafts could be separated. In the wild-type 3T3- L l adipocytes, Glut-4 was found to be translocated into both caveolae and non-caveolar lipid rafts. However, in Cav1 RNAi adipocytes, Glut-4 was localized predominantly in non-caveolar lipid rafts. After the removal of insulin, caveolaelocalized Glut-4 was internalized faster than non-caveolar lipid raft-associated Glut-4. The internalization of Glut-4 from plasma membrane was significantly decreased in Cav-1 RNAi adipocytes. These results suggest that insulin-stimulated Glut-4 translocation and glucose uptake are caveolae-independent events. Caveolae play a role in the internalization of Glut-4 from plasma membrane after the removal of insulin.
文摘Although mental health symptoms in children and adolescents are shown to predict young adult mental health outcomes, long-term prospective studies of childhood cohorts are few. The aim of the present study was to analyze the prospective importance of internalized mental health symptoms in adolescence for internalized symptoms in adulthood. Methods: A community-based prospective longitudinal cohort provided information by questionnaire about psychological status at age 16 and 43 (n=1010, representing 94.3% of those still alive). Socio-demographic variables which were indicative of possible childhood adversity (parental class, absence, illness, unemployment, relationship, crowding, number of moves) were treated as confounders and controlled for in ordinal regression. Results: For both women and men, internalizing mental health symptoms reported at 16 significantly predicted the same outcome at 43 years, after controlling for previous adverse environmental conditions (OR =1.2 for women, 1.3 for men). Conclusion: In this representative cohort studied over 27 years with excellent retention rates, the occurrence of self-reported worry, panic and sadness in mid-adolescence significantly increased the likelihood of similar states in middle adulthood.
文摘基于国际比较的地方空间规划的范围和工具研究An International Comparison of the Scope and Instruments of Local Spatial Planning源自:The TownPlanning Review,2024,95(2):197-217作者:MaciejJNowak,StefanieDühr,Sergio Peña,et al.推荐:申明锐,南京大学建筑与城市规划学院。shenmingr@nju.edu.cn.
基金Supported by the Fundamental Research Funds for the Central Universities(2024ZYGXZR047)the National Natural Science Foundation of China(62373156)the Guangdong Basic and Applied Basic Research Foundation(2024A1515011736)。
文摘This article investigates the robust current tracking control problem of three-phase grid-connected inverters with LCL filter under external disturbance by a dynamic state feedback control method.First,this paper constructs an internal model to learn the information of the states and input of the grid-connected inverter under steady state.Second,by utilizing the internal model principle,the paper turns the tracking control problem into the robust stabilization control problem based on some appropriate coordinate transformations.Then,The paper designs a dynamics state feedback control law to deal with this robust stabilization problem,and thus the solution of the robust current tracking control problem of three-phase grid-connected inverters can be obtained.This control method can ensure the asymptotic stability of the closedloop system.Finally,the paper illustrates the effectiveness of the proposed control approach through several groups of simulations,and compares it with the feedforward control method to verify the robustness of the proposed control method to uncertain parameters.
文摘Analysis Method of ^(131)I Activity in Carbon Cartridge and Internal Dose Assessment for Nuclear Medicine Workers.Shuo Wang1,Fei Tuo1,Jian-feng Zhang1,Xiao-liang Li1,Bao-lu Yang1,Qiang Zhou1,Ze-shu Li1,Shu-ying Kong1,and Wei-hao Qin1(1.National Institute for Radiological Protection,Chinese Center for Disease Control and Prevention,Beijing,100088,China.)
文摘Journal of Iron and Steel Research International(中文刊名:钢铁研究学报(英文版),下文简称JISRI)是由中国钢铁工业协会主管、中国钢研科技集团有限公司主办的冶金领域学术期刊(CN 11-3678/TF,ISSN 1006-706X)。JISRI于1994年创刊,月刊,主编为赵栋梁教授和Hongbiao Dong教授。
文摘The International Radiation Symposium(IRS) is a quadrennial symposium of the International Radiation Commission(IRC), one of the 11 commissions under the International Association of Meteorology and Atmospheric Sciences(IAMAS).The role of the IRC is to promote fundamental research in atmospheric radiation and its applications to practical problems.
文摘The year 2025 witnessed the profound evolution of the international landscape,characterized by intensified major-power rivalry,protracted geopolitical conflicts,erosion of multilateral mechanisms,and increasingly obsolete international rules.The old order is dying,and the new one is yet to be born.The future trajectory of the world hinges largely on whether nations,particularly major powers,can manage differences and seek cooperation through effective communication amidst the complex and volatile environment.
文摘In 2025,the global landscape has undergone profound transformations,with the international architecture continuing to adjust.The fragility and uncertainty of international security have become increasingly pronounced.Frequent regional conflicts and political instability have triggered a deep sense of insecurity,while latent risks have emerged one after another,exacerbating turbulence and disorder.Some countries still cling to a zero-sum mindset,selectively applying or discarding international rules based on their interests.Hegemonism and unilateralism have severely undermined the UN-centered international system,leading to a resurgence of geopolitical rivalry and intensified bloc confrontation.The provision of global public goods remains severely inadequate,security risks continue to accumulate,and the journey toward effective global security governance remains long and challenging.
文摘GLOBAL GOVERNANCE AS AN INSTRUMENT FOR TRANSFORMING CHAOS INTO ORDERLY MULTIPOLARITY The current global geopolitical situation,marked by instability,the erosion of the post-WWII international order and the weakening of US unipolar dominance,requires joint efforts by major international actors and the wider international community to establish a functional international order for the twenty-first century.
文摘At the IEC,Chinese experts have been contributing their expertise to international standardization.As one of them,Ma Dejun has grown from an inexperienced explorer in the field of standardization into a distinguished expert driving the development of international standards in key sectors over the past 35 years.He was presented with the 2025 Lord Kelvin Award at the 89th IEC General Meeting held in New Delhi,India,in September 2025.Thus,he became the first Chinese expert to receive the highest honor bestowed by the IEC.In an exclusive interview with Ma Dejun,he reviewed his original aspiration behind his decades-long journey in international standardization,shared his experience and insights on promoting international standards,and looked forward to China's future role on the international standardiz ation stage.
文摘I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single investigator or an isolated team.My advice is intended for early-career scientists.The product of the collaboration may be high-impact research publications,enhanced geophysical monitoring capabilities in a foreign country,or an advanced training course.Choosing the right international partner is the most important step.Keeping an open mind and being receptive to suggestions to modify the initial concept is critical.Other key steps include having a mutually agreed upon plan with achievable goals and well-defined expected outcomes.International cooperation is a richly rewarding experience that accelerates progress in the Earth Sciences.
文摘The China Expo Forum for International Cooperation(CEFCO)2026 was held in Wuhan,Hubei Province,China,on January 22.The opening ceremony was attended by Li Qing Shuang,Vice President of the China Council for the Promotion of International Trade(CCPIT);Zhu Yuji,Deputy Secretary of the Hubei Provincial Committee of the Communist Party of China;Sheng Yue Chun,Member of the Standing Committee of the Hubei Provincial Committee of the Communist Party of China and Secretary of the Wuhan Municipal Committee;Punita Bhansal,President of the Global Association of the Exhibition Industry(UFI);Marsha Flanagan,President and CEO of the International Association of Exhibitions and Events(IAEE);Vincent Polito,CEO of the Society of Independent Show Organizers(SISO);and Leonie Ashford,Board Member of the International Congress and Convention Association(ICCA).
文摘The Chinese Journal of Chemical Engineering is the official journal of The Chemical Industry and Engineering Society of China and published by the Chemical Industry Press Co.,Ltd.The aim of the journal is to develop the international exchange of scientific and technical information in the field of chemical engineering.Submission of Papers All papers will be submitted on line.
