The target thickness for nitrogen was determined from the beam energy loss in HIRFL-CSRe during the experimental study of the K-REC process in 197 MeV/u Xe54＋-N2 collisions. Furthermore, the corresponding integrated ...The target thickness for nitrogen was determined from the beam energy loss in HIRFL-CSRe during the experimental study of the K-REC process in 197 MeV/u Xe54＋-N2 collisions. Furthermore, the corresponding integrated luminosity of （1.15±0.06） x 10^30 cm-2 was obtained. As an independent check on the energy-loss method, we have also determined the integrated luminosity by measuring the produced X-rays from the K-REC process with a known differential cross section. The values of （1.12±0.06） x 10^30 and （1.09±0.06） x 1030 cm-2 were obtained by using two high-purity germanium （HPGe） detectors which were oriented at 90% and 120%with respect to the beam path, respectively. The consistent results confirmed the feasibility of the energy-loss method, which may have an important impact on future internal target experiments at HIRFL-CSRe.展开更多
Objective To assess the effect of tetrandrine (Tet) pulmonary targeting microspheres on hypoxic pulmonary hypertension and evaluate its selective action on pulmonary circulation.Methods Twenty rats were exposed to h...Objective To assess the effect of tetrandrine (Tet) pulmonary targeting microspheres on hypoxic pulmonary hypertension and evaluate its selective action on pulmonary circulation.Methods Twenty rats were exposed to hypoxic conditions for 3 weeks. Ten rats were used as normoxic controls. We administered Tet pulmonary targeting microspheres to 10 hypoxic rats and Tet aqueous solution to 10 hypoxic rats and the 10 control rats. Mean pulmonary arterial pressure (mPAP) was measured by a right cardiac catheterization, and mean systemic blood pressure (mSBP) was measured by left femoral catheterization. Results Rats exposed to hypoxia developed pulmonary hypertension. The decrease in mPAP in rats treated with Tet pulmonary targeting microspheres was significantly greater than that in rats receiving Tet aqueous solution (P【0.05), and the effects were longer with Tet pulmonary targeting microspheres. Moreover, Tet pulmonary targeting microspheres, unlike Tet aqueous solution, did not decrease mSBP.Conclusion Tet pulmonary targeting microspheres were more effective than Tet aqueous solution in treating hypoxic pulmonary hypertension and acted selectively on the pulmonary circulation.展开更多
The opportunities and challenges of performing transfer reactions in inverse kinematics using the ^(16,18)O beams at the experimental Cooler Storage Ring(CSRe)of the Heavy Ion Research Facility in Lanzhou(HIRFL)with t...The opportunities and challenges of performing transfer reactions in inverse kinematics using the ^(16,18)O beams at the experimental Cooler Storage Ring(CSRe)of the Heavy Ion Research Facility in Lanzhou(HIRFL)with the internal gas-jet target are discussed herein.The kinematics,differential cross sections for various transfer reactions using the ^(16,18)O beam with incident energies of 30 and 100 MeV/nucleon,and the H_(2)-or D_(2)-gas-jet targets are compared.The^(16)O beam at 100 MeV/nucleon with an intensity of≥10^(6)pps interacting with the H2-gas-jet target is recommended as the first transfer reaction at HIRFL-CSRe.展开更多
基金Supported by National Natural Science Foundation of China(11179017,11105201,U1532130,and U1332206)
文摘The target thickness for nitrogen was determined from the beam energy loss in HIRFL-CSRe during the experimental study of the K-REC process in 197 MeV/u Xe54＋-N2 collisions. Furthermore, the corresponding integrated luminosity of （1.15±0.06） x 10^30 cm-2 was obtained. As an independent check on the energy-loss method, we have also determined the integrated luminosity by measuring the produced X-rays from the K-REC process with a known differential cross section. The values of （1.12±0.06） x 10^30 and （1.09±0.06） x 1030 cm-2 were obtained by using two high-purity germanium （HPGe） detectors which were oriented at 90% and 120%with respect to the beam path, respectively. The consistent results confirmed the feasibility of the energy-loss method, which may have an important impact on future internal target experiments at HIRFL-CSRe.
文摘Objective To assess the effect of tetrandrine (Tet) pulmonary targeting microspheres on hypoxic pulmonary hypertension and evaluate its selective action on pulmonary circulation.Methods Twenty rats were exposed to hypoxic conditions for 3 weeks. Ten rats were used as normoxic controls. We administered Tet pulmonary targeting microspheres to 10 hypoxic rats and Tet aqueous solution to 10 hypoxic rats and the 10 control rats. Mean pulmonary arterial pressure (mPAP) was measured by a right cardiac catheterization, and mean systemic blood pressure (mSBP) was measured by left femoral catheterization. Results Rats exposed to hypoxia developed pulmonary hypertension. The decrease in mPAP in rats treated with Tet pulmonary targeting microspheres was significantly greater than that in rats receiving Tet aqueous solution (P【0.05), and the effects were longer with Tet pulmonary targeting microspheres. Moreover, Tet pulmonary targeting microspheres, unlike Tet aqueous solution, did not decrease mSBP.Conclusion Tet pulmonary targeting microspheres were more effective than Tet aqueous solution in treating hypoxic pulmonary hypertension and acted selectively on the pulmonary circulation.
基金Supported by the National Key Research and Development Program of China(2023YFA1606702)the National Natural Science Foundation of China(12275007)the funding from Heavy Ion Research Facility in Lanzhou(HIR2021PY002)。
文摘The opportunities and challenges of performing transfer reactions in inverse kinematics using the ^(16,18)O beams at the experimental Cooler Storage Ring(CSRe)of the Heavy Ion Research Facility in Lanzhou(HIRFL)with the internal gas-jet target are discussed herein.The kinematics,differential cross sections for various transfer reactions using the ^(16,18)O beam with incident energies of 30 and 100 MeV/nucleon,and the H_(2)-or D_(2)-gas-jet targets are compared.The^(16)O beam at 100 MeV/nucleon with an intensity of≥10^(6)pps interacting with the H2-gas-jet target is recommended as the first transfer reaction at HIRFL-CSRe.
