Distraction osteogenesis,or the Illizarov technique,induces bone regeneration using distractive mechanical forces.Nevertheless,Wolff's law holds that bone adapts to reverse compressive mechanical loads,growing den...Distraction osteogenesis,or the Illizarov technique,induces bone regeneration using distractive mechanical forces.Nevertheless,Wolff's law holds that bone adapts to reverse compressive mechanical loads,growing denser in areas of high pressure and resorbing in zones of low pressure.These two forms of new bone formation together suggest that mechanical stimuli play an important role in bone remodeling and regeneration.The therapeutic efficacy of distraction osteogenesis has been recognized in orthopedics and maxillofacial surgeries.Distraction osteogenesis was even used for the regeneration of various other tissues/organs,such as blood vessels and skin(e.g.,in the treatment of limb ischemic diseases and foot ulcers),suggesting the principle of distraction histogenesis.However,the underlying mechanisms,particularly those of the cross-organ effects and in terms of mechanotransduction,remain poorly understood.Thus,this review aims to explore the recent advances in research on musculoskeletal regeneration and its association with mechanosensitive channels from a new interdisciplinary application perspective.The contents can provide insights into potential research directions for understanding the molecular mechanisms of musculoskeletal regeneration and its clinical applications.展开更多
The internal structures of cells as the basic units of life are a major wonder of the microscopic world.Cellular images provide an intriguing window to help explore and understand the composition and function of these...The internal structures of cells as the basic units of life are a major wonder of the microscopic world.Cellular images provide an intriguing window to help explore and understand the composition and function of these structures.Scientific imagery combined with artistic expression can further expand the potential of imaging in educational dissemination and interdisciplinary applications.展开更多
In the context of globalization, there is an urgent need to cultivate interdisciplinary talents with knowledge of tourism management and proficiency in English. Guided by the New Liberal Arts concept, the “Tourism Ma...In the context of globalization, there is an urgent need to cultivate interdisciplinary talents with knowledge of tourism management and proficiency in English. Guided by the New Liberal Arts concept, the “Tourism Management + English” talent cultivation model has emerged. Taking the tourism management talent cultivation of Hainan province as an example, this article analyzes the issues present in traditional tourism management programs and proposes a construction framework that involves conducting in-depth industry research, improving management systems, increasing financial support, implementing strict and standardized management, optimizing talent cultivation plans, highlighting distinctive training features, and strengthening industry services.展开更多
Amidst escalating energy demands and intensifying environmental pressures,advanced phase change materials(PCMs)have emerged as highly efficient and sustainable storage solutions,owing to their unique operational princ...Amidst escalating energy demands and intensifying environmental pressures,advanced phase change materials(PCMs)have emerged as highly efficient and sustainable storage solutions,owing to their unique operational principles.However,pristine PCMs encounter a multitude of challenges,including susceptibility to leakage,inferior thermal/electrical conductivity,inadequate light responsiveness,intrinsic rigidity,and limited functionality,which impede their effectiveness in addressing the complex demands of real-world applications.Longitudinal confinement of PCMs using advanced multifunctional 1D materials is accepted as a cutting-edge solution to these limitations.A corresponding comprehensive review of longitudinally confined composite PCMs is thus imperative for subsequent studies and yet is missing from the literature,unlike reviews of 0D,2D,and 3D materials for PCMs.Herein,this review systematically highlights the diverse roles of longitudinal materials in PCMs and analyzes the relationships between their architectures and thermophysical properties,with particular emphasis on design principles and advanced multifunctional interdisciplinary applications.Additionally,we provide an in-depth understanding of thermal transfer,energy conversion mechanisms,and rationalized routes to high-efficiency energy conversion PCMs.Finally,we introduce critical considerations for current challenges and future solutions to them,hoping to offer constructive guidance and facilitate significant breakthroughs for longitudinally confined composite PCMs in both fundamental interdisciplinary research and commercial applications.展开更多
基金supported by grants from the National Natural Science Foundation of China(No.82360429 and 82060406)Natural Science Foundation of Guangxi,China(No.2023GXNSFAA026474)+1 种基金Advanced Innovation Teams and Xinghu Scholars Program of Guangxi Medical University,China Postdoctoral Science Foundation(No.2019M650235)Key R&D Project of Qingxiu District,Nanning,Guangxi,China(No.2021003).
文摘Distraction osteogenesis,or the Illizarov technique,induces bone regeneration using distractive mechanical forces.Nevertheless,Wolff's law holds that bone adapts to reverse compressive mechanical loads,growing denser in areas of high pressure and resorbing in zones of low pressure.These two forms of new bone formation together suggest that mechanical stimuli play an important role in bone remodeling and regeneration.The therapeutic efficacy of distraction osteogenesis has been recognized in orthopedics and maxillofacial surgeries.Distraction osteogenesis was even used for the regeneration of various other tissues/organs,such as blood vessels and skin(e.g.,in the treatment of limb ischemic diseases and foot ulcers),suggesting the principle of distraction histogenesis.However,the underlying mechanisms,particularly those of the cross-organ effects and in terms of mechanotransduction,remain poorly understood.Thus,this review aims to explore the recent advances in research on musculoskeletal regeneration and its association with mechanosensitive channels from a new interdisciplinary application perspective.The contents can provide insights into potential research directions for understanding the molecular mechanisms of musculoskeletal regeneration and its clinical applications.
基金supported by the Fundamental Research Funds for the Central Universities(No.226-2024-00038),China.
文摘The internal structures of cells as the basic units of life are a major wonder of the microscopic world.Cellular images provide an intriguing window to help explore and understand the composition and function of these structures.Scientific imagery combined with artistic expression can further expand the potential of imaging in educational dissemination and interdisciplinary applications.
基金This research is a product of the project“Innovation and Practice of Cultivating High-Quality and Interdisciplinary Talents in‘Tourism Management+English’Based on the New Liberal Arts Concept”(RHYxgnw2024-20)It is also a research outcome of the school-level Ideological and Political Education in Courses project(RHKSsk2024-28).
文摘In the context of globalization, there is an urgent need to cultivate interdisciplinary talents with knowledge of tourism management and proficiency in English. Guided by the New Liberal Arts concept, the “Tourism Management + English” talent cultivation model has emerged. Taking the tourism management talent cultivation of Hainan province as an example, this article analyzes the issues present in traditional tourism management programs and proposes a construction framework that involves conducting in-depth industry research, improving management systems, increasing financial support, implementing strict and standardized management, optimizing talent cultivation plans, highlighting distinctive training features, and strengthening industry services.
基金supported by National Natural Science Foundation of China(No.51902025)Open Research Fund of Guangdong Advanced Carbon Materials Co.,Ltd(No.Kargen-2024B1707).
文摘Amidst escalating energy demands and intensifying environmental pressures,advanced phase change materials(PCMs)have emerged as highly efficient and sustainable storage solutions,owing to their unique operational principles.However,pristine PCMs encounter a multitude of challenges,including susceptibility to leakage,inferior thermal/electrical conductivity,inadequate light responsiveness,intrinsic rigidity,and limited functionality,which impede their effectiveness in addressing the complex demands of real-world applications.Longitudinal confinement of PCMs using advanced multifunctional 1D materials is accepted as a cutting-edge solution to these limitations.A corresponding comprehensive review of longitudinally confined composite PCMs is thus imperative for subsequent studies and yet is missing from the literature,unlike reviews of 0D,2D,and 3D materials for PCMs.Herein,this review systematically highlights the diverse roles of longitudinal materials in PCMs and analyzes the relationships between their architectures and thermophysical properties,with particular emphasis on design principles and advanced multifunctional interdisciplinary applications.Additionally,we provide an in-depth understanding of thermal transfer,energy conversion mechanisms,and rationalized routes to high-efficiency energy conversion PCMs.Finally,we introduce critical considerations for current challenges and future solutions to them,hoping to offer constructive guidance and facilitate significant breakthroughs for longitudinally confined composite PCMs in both fundamental interdisciplinary research and commercial applications.
