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In-Memory Probabilistic Computing Using Gate-Tunable Layer Pseudospins in van der Waals Heterostructures
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作者 Jiao Xie Jun-Lin Xiong +2 位作者 Bin Cheng Shi-Jun Liang Feng Miao 《Chinese Physics Letters》 2025年第4期9-22,共14页
Layer pseudospins,exhibiting quantum coherence and precise multistate controllability,present significant potential for the advancement of future computing technologies.In this work,we propose an in-memory probabilist... Layer pseudospins,exhibiting quantum coherence and precise multistate controllability,present significant potential for the advancement of future computing technologies.In this work,we propose an in-memory probabilistic computing scheme based on the electrical manipulation of layer pseudospins in layered materials,by exploiting the interaction between real spins and layer pseudospins. 展开更多
关键词 layer pseudospinsexhibiting layered materialsby real spins probabilistic computing advancement future computing technologiesin electrical manipulation layer pseudospins memory computing gate tunable layer pseudospins
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Full-Blind Delegating Private Quantum Computation 被引量:1
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作者 Wenjie Liu Zhenyu Chen +2 位作者 Jinsuo Liu Zhaofeng Su Lianhua Chi 《Computers, Materials & Continua》 SCIE EI 2018年第8期211-223,共13页
The delegating private quantum computation(DQC)protocol with the universal quantum gate set{X,Z,H,P,R,CNOT}was firstly proposed by Broadbent et al.[Broadbent(2015)],and then Tan et al.[Tan and Zhou(2017)]tried to put ... The delegating private quantum computation(DQC)protocol with the universal quantum gate set{X,Z,H,P,R,CNOT}was firstly proposed by Broadbent et al.[Broadbent(2015)],and then Tan et al.[Tan and Zhou(2017)]tried to put forward a half-blind DQC protocol(HDQC)with another universal set{H,P,CNOT,T}.However,the decryption circuit of Toffoli gate(i.e.T)is a little redundant,and Tan et al.’s protocol[Tan and Zhou(2017)]exists the information leak.In addition,both of these two protocols just focus on the blindness of data(i.e.the client’s input and output),but do not consider the blindness of computation(i.e.the delegated quantum operation).For solving these problems,we propose a full-blind DQC protocol(FDQC)with quantum gate set{H,P,CNOT,T},where the desirable delegated quantum operation,one of{H,P,CNOT,T},is replaced by a fixed sequence(H,P,CZ,CNOT,T)to make the computation blind,and the decryption circuit of Toffoli gate is also optimized.Analysis shows that our protocol can not only correctly perform any delegated quantum computation,but also holds the characteristics of data blindness and computation blindness. 展开更多
关键词 Delegating private quantum computation universal quantum gate set full-blind Toffoli gate circuit optimization
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All-microwave CZ gate based on fixed-frequency driven coupler
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作者 Wanpeng Gao Xiaoliang He +5 位作者 Zhengqi Niu Daqiang Bao Kuang Liu Junfeng Chen Zhen Wang Z.R.Lin 《Chinese Physics B》 2025年第4期201-205,共5页
High-quality entangling gates are crucial for scalable quantum information processing.Implementing all-microwave two-qubit gates on fixed-frequency transmons offers advantages in reducing wiring complexity,but the gat... High-quality entangling gates are crucial for scalable quantum information processing.Implementing all-microwave two-qubit gates on fixed-frequency transmons offers advantages in reducing wiring complexity,but the gate performance is often limited due to the residual ZZ interaction and the frequency crowding problem.Here,we introduce a novel scheme that enables a microwave drive-activated CZ gate compatible with the coupler structure to suppress the residual ZZ interaction.The microwave drive is applied to the coupler and the microwave drive frequency remains far detuned from the system’s transition frequency to alleviate the frequency crowding problem.We model the gate process analytically and demonstrate a theoretical gate fidelity up to 99.9%numerically.Our scheme is compatible with current coupler-structure-based circuits,and insensitive to microwave crosstalk,showing a possible path for all-microwave quantum operations at scale. 展开更多
关键词 quantum computing superconducting qubit two-qubit gate
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Low‑Power Memristor for Neuromorphic Computing:From Materials to Applications
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作者 Zhipeng Xia Xiao Sun +3 位作者 Zhenlong Wang Jialin Meng Boyan Jin Tianyu Wang 《Nano-Micro Letters》 2025年第9期265-289,共25页
As an emerging memory device,memristor shows great potential in neuromorphic computing applications due to its advantage of low power consumption.This review paper focuses on the application of low-power-based memrist... As an emerging memory device,memristor shows great potential in neuromorphic computing applications due to its advantage of low power consumption.This review paper focuses on the application of low-power-based memristors in various aspects.The concept and structure of memristor devices are introduced.The selection of functional materials for low-power memristors is discussed,including ion transport materials,phase change materials,magnetoresistive materials,and ferroelectric materials.Two common types of memristor arrays,1T1R and 1S1R crossbar arrays are introduced,and physical diagrams of edge computing memristor chips are discussed in detail.Potential applications of low-power memristors in advanced multi-value storage,digital logic gates,and analogue neuromorphic computing are summarized.Furthermore,the future challenges and outlook of neuromorphic computing based on memristor are deeply discussed. 展开更多
关键词 MEMRISTOR Low power Multi-value storage Digital logic gates Neuromorphic computing
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Robust quantum gate optimization with first-order derivatives of ion–phonon and ion–ion couplings in trapped ions
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作者 Jing-Bo Wang 《Chinese Physics B》 2025年第4期287-294,共8页
Trapped ion hardware has made significant progress recently and is now one of the leading platforms for quantum computing.To construct two-qubit gates in trapped ions,experimentalmanipulation approaches for ion chains... Trapped ion hardware has made significant progress recently and is now one of the leading platforms for quantum computing.To construct two-qubit gates in trapped ions,experimentalmanipulation approaches for ion chains are becoming increasingly prevalent.Given the restricted control technology,how implementing high-fidelity quantum gate operations is crucial.Many works in current pulse design optimization focus on ion–phonon and effective ion–ion couplings while ignoring the first-order derivative terms expansion impacts of these two terms brought on by experiment defects.This paper proposes a novel robust quantum control optimization method in trapped ions.By introducing the first-order derivative terms caused by the error into the optimization cost function,we generate an extremely robust Mølmer–Sørensen gate with infidelity below 10^(−3) under a drift noise range of±10 kHz,the relative robustness achieves a tolerance of±5%,compared to the 200-kHz frequency spacing between phonon modes,and for time noise drift,the tolerance reached to 2%.Our work reveals the vital role of the first-order derivative terms of coupling in trapped ion pulse control optimization,especially the first-order derivative terms of ion–ion coupling.It provides a robust optimization scheme for realizing more efficient entangled states in trapped ion platforms. 展开更多
关键词 trapped ion quantum computing robust optimization high-fidelity quantum gates magnus expansion
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Fast Ion Gates without the Lamb-Dicke Approximation by Robust Quantum Optimal Control
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作者 Ran Liu Xiaodong Yang +2 位作者 Yiheng Lin Yao Lu Jun Li 《Chinese Physics Letters》 2025年第8期75-82,共8页
We present a robust quantum optimal control framework for implementing fast entangling gates on ion-trap quantum processors.The framework leverages tailored laser pulses to drive the multiple vibrational sidebands of ... We present a robust quantum optimal control framework for implementing fast entangling gates on ion-trap quantum processors.The framework leverages tailored laser pulses to drive the multiple vibrational sidebands of the ions to create phonon-mediated entangling gates and,unlike the state of the art,requires neither weakcoupling Lamb-Dicke approximation nor perturbation treatment.With the application of gradient-based optimal control,it enables finding amplitude-and phase-modulated laser control protocols that work without the Lamb-Dicke approximation,promising gate speeds on the order of microseconds comparable to the characteristic trap frequencies.Also,robustness requirements on the temperature of the ions and initial optical phase can be conveniently included to pursue high-quality fast gates against experimental imperfections.Our approach represents a step in speeding up quantum gates to achieve larger quantum circuits for quantum computation and simulation,and thus can find applications in near-future experiments. 展开更多
关键词 quantum optimal control framework gradient based optimal control quantum computation Lamb Dicke approximation fast ion gates tailored laser pulses entangling gates robust quantum optimal control
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Ultrafast Ternary Content-Addressable Nonvolatile Floating-Gate Memory Based on van der Waals Heterostructures
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作者 Peng Song Xuanye Liu +8 位作者 Jiequn Sun Nuertai Jiazila Chijun Wei Hui Gao Chengze Du Hui Guo Haitao Yang Lihong Bao Hong-Jun Gao 《Chinese Physics Letters》 2025年第6期297-304,I0001-I0006,共14页
As a typical in-memory computing hardware design, nonvolatile ternary content-addressable memories(TCAMs) enable the logic operation and data storage for high throughout in parallel big data processing. However,TCAM c... As a typical in-memory computing hardware design, nonvolatile ternary content-addressable memories(TCAMs) enable the logic operation and data storage for high throughout in parallel big data processing. However,TCAM cells based on conventional silicon-based devices suffer from structural complexity and large footprintlimitations. Here, we demonstrate an ultrafast nonvolatile TCAM cell based on the MoTe2/hBN/multilayergraphene (MLG) van der Waals heterostructure using a top-gated partial floating-gate field-effect transistor(PFGFET) architecture. Based on its ambipolar transport properties, the carrier type in the source/drain andcentral channel regions of the MoTe2 channel can be efficiently tuned by the control gate and top gate, respectively,enabling the reconfigurable operation of the device in either memory or FET mode. When working inthe memory mode, it achieves an ultrafast 60 ns programming/erase speed with a current on-off ratio of ∼105,excellent retention capability, and robust endurance. When serving as a reconfigurable transistor, unipolar p-typeand n-type FETs are obtained by adopting ultrafast 60 ns control-gate voltage pulses with different polarities.The monolithic integration of memory and logic within a single device enables the content-addressable memory(CAM) functionality. Finally, by integrating two PFGFETs in parallel, a TCAM cell with a high current ratioof ∼10^(5) between the match and mismatch states is achieved without requiring additional peripheral circuitry.These results provide a promising route for the design of high-performance TCAM devices for future in-memorycomputing applications. 展开更多
关键词 van der waals heterostructures floating gate memory memory computing parallel big data processing nonvolatile memory van der waals heterostructure ternary content addressable memory top gated partial floating gate field effect transistor
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Analysis of Heralded Higher-Fidelity Two-Qubit Entangling Gates with Self-Correction
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作者 Yuan Sun 《Chinese Physics Letters》 2025年第7期156-170,共15页
For the quantum error correction and noisy intermediate-scale quantum algorithms to function with high efficiency,the raw fidelity of quantum logic gates on physical qubits needs to satisfy strict requirements.The neu... For the quantum error correction and noisy intermediate-scale quantum algorithms to function with high efficiency,the raw fidelity of quantum logic gates on physical qubits needs to satisfy strict requirements.The neutral atom quantum computing equipped with Rydberg blockade gates has made impressive progress recently,which makes it worthwhile to explore its potential in the two-qubit entangling gates,including the controlledphase gate,and in particular,the CZ gate.Provided the quantum coherence is well preserved,improving the fidelity of Rydberg blockade gates calls for special mechanisms to deal with adverse effects caused by realistic experimental conditions.Here,the heralded very-high-fidelity Rydberg blockade controlled-phase gate is designed to address these issues,which contains self-correction and projection as the key steps.This trailblazing method builds upon the previously established buffer-atom-mediated gate framework,with a special form of symmetry under parity–time transformation playing a crucial role in the process.We further analyze the performance with respect to a few typical sources of imperfections.This procedure can also be regarded as quantum hardware error correction or mitigation.While this paper by itself does not cover every single subtle issue and still contains many oversimplifications,we find it reasonable to anticipate a very-high-fidelity two-qubit quantum logic gate operated in the sense of heralded but probabilistic,whose gate error can be reduced to the level of 10^(-4)–10^(-6)or even lower with reasonably high possibilities. 展开更多
关键词 rydberg blockade gates controlledphase gateand neutral atom quantum computing quantum coherence quantum error correction cz gateprovided heralded higher fidelity two qubit entangling gates self correction
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An improvement to computational efficiency of the drain current model for double-gate MOSFET
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作者 周幸叶 张健 +5 位作者 周致赜 张立宁 马晨月 吴文 赵巍 张兴 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第9期392-395,共4页
As a connection between the process and the circuit design, the device model is greatly desired for emerging devices, such as the double-gate MOSFET. Time efficiency is one of the most important requirements for devic... As a connection between the process and the circuit design, the device model is greatly desired for emerging devices, such as the double-gate MOSFET. Time efficiency is one of the most important requirements for device modeling. In this paper, an improvement to the computational efficiency of the drain current model for double-gate MOSFETs is extended, and different calculation methods are compared and discussed. The results show that the calculation speed of the improved model is substantially enhanced. A two-dimensional device simulation is performed to verify the improved model. Furthermore, the model is implemented into the HSPICE circuit simulator in Verilog-A for practical application. 展开更多
关键词 computational efficiency compact model DOUBLE-GATE MOSFET
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All-optical logic gate computing for high-speed parallel information processing 被引量:5
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作者 Shuming Jiao Junwei Liu +6 位作者 Liwen Zhang Feihong Yu Guomeng Zuo Jingming Zhang Fang Zhao Weihao Lin Liyang Shao 《Opto-Electronic Science》 2022年第9期11-32,共22页
Optical computing and optical neural network have gained increasing attention in recent years because of their potential advantages of parallel processing at the speed of light and low power consumption by comparison ... Optical computing and optical neural network have gained increasing attention in recent years because of their potential advantages of parallel processing at the speed of light and low power consumption by comparison with electronic computing.The optical implementation of the fundamental building blocks of a digital computer,i.e.logic gates,has been investigated extensively in the past few decades.Optical logic gate computing is an alternative approach to various analogue optical computing architectures.In this paper,the latest development of optical logic gate computing with different kinds of implementations is reviewed.Firstly,the basic concepts of analogue and digital computing with logic gates in the electronic and optical domains are introduced.And then a comprehensive summary of various optical logic gate schemes including spatial encoding of light field,semiconductor optical amplifiers(SOA),highly nonlinear fiber(HNLF),microscale and nanoscale waveguides,and photonic crystal structures is presented.To conclude,the formidable challenges in developing practical all-optical logic gates are analyzed and the prospects of the future are discussed. 展开更多
关键词 logic gate optical computing artificial intelligence WAVEGUIDE crystal structure
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Study of Decoherence of Elementary Gates Implemented in a Chain of Few Nuclear Spins Quantum Computer Model 被引量:2
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作者 G. V. López P. López 《Journal of Modern Physics》 2012年第1期85-101,共17页
We study the phenomenon of decoherence during the operation of one qubit transformation, controlled-not (CNOT) and controlled-controlled-not (C2NOT) quantum gates in a quantum computer model formed by a linear chain o... We study the phenomenon of decoherence during the operation of one qubit transformation, controlled-not (CNOT) and controlled-controlled-not (C2NOT) quantum gates in a quantum computer model formed by a linear chain of three nuclear spins system. We make this study with different type of environments, and we determine the associated decoherence time as a function of the dissipative parameter. We found that the dissipation parameter to get a well defined quantum gates (without significant decoherence) must be within the range of . We also study the behavior of the purity parameter for these gates and different environments and found linear or quadratic decays of this parameter depending on the type of environments. 展开更多
关键词 DECOHERENCE Not GATE Controlled-Not GATES Controlled-Controlled-Not GATE Nuclear Spin CHAIN QUANTUM computer
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Nonadiabatic Geometric Quantum Computation with Asymmetric Superconducting Quantum Interference Device
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作者 HAO San-Ru HOU Bo-Yu XI Xiao-Qiang YUE Rui-Hong 《Communications in Theoretical Physics》 SCIE CAS CSCD 2002年第9期285-291,共7页
We propose a method of controlling the dc-SQUID (superconducting quantum interference device) systemby changing the gate voltages, which controls the amplitude of the fictitious magnetic fields Bz, and the externallya... We propose a method of controlling the dc-SQUID (superconducting quantum interference device) systemby changing the gate voltages, which controls the amplitude of the fictitious magnetic fields Bz, and the externallyapplied current that produces the piercing magnetic fiux φx for the dc-SQUID system. We have also introduced aphysical model for the dc-SQUID system. Using this physical model, one can obtain the non-adiabatic geometric phasegate for the single qubit and the non-adiabatic conditional geometric phase gate (controlled NOT gate) for the twoqubits. It is shown that when the gate voltage and the externally applied current of the dc-SQUID system satisfies anappropriate constraint condition, the charge state evolution can be controlled exactly on a dynamic phase free path. Thenon-adiabatic evolution of the charge states is given as well. 展开更多
关键词 NON-ADIABATIC GEOMETRIC phase gate DC-SQUID quantum computation
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Nonadiabatic Geometric Quantum Computation with Asymmetric Superconducting Quantum Interference Device
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作者 HAO San-Ru HOU Bo-Yu XI Xiao-Qiang YUE Rui-Hong 《Communications in Theoretical Physics》 SCIE CAS CSCD 2002年第3期285-291,共7页
We propose a method of controlling the dc-SQUID (superconducting quantum interference device) system by changing the gate voltages, which controls the amplitude of the fictitious magnetic fields B-z, and the externall... We propose a method of controlling the dc-SQUID (superconducting quantum interference device) system by changing the gate voltages, which controls the amplitude of the fictitious magnetic fields B-z, and the externally applied current that produces the piercing magnetic flux Phi(x) for the dc-SQUID system. We have also introduced a physical model for the dc-SQUID system. Using this physical model, one can obtain the non-adiabatic geometric phase gate for the single qubit and the non-adiabatic conditional geometric phase gate (controlled NOT gate) for the two qubits. It is shown that when the gate voltage and the externally applied current of the dc-SQUID system satisfies an appropriate constraint condition, the charge state evolution can be controlled exactly on a dynamic phase free path. The non-adiabatic evolution of the charge states is given as well. 展开更多
关键词 non-adiabatic geometric phase gate DC-SQUID quantum computation
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Computational Cluster with Entangled States
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作者 Nikolay Raychev 《Journal of Applied Mathematics and Physics》 2016年第9期1777-1786,共11页
In this article the inherent computational power of the quantum entangled cluster states examined by measurement-based quantum computations is studied. By defining a common framework of rules for measurement of quantu... In this article the inherent computational power of the quantum entangled cluster states examined by measurement-based quantum computations is studied. By defining a common framework of rules for measurement of quantum entangled cluster states based on classical computations, the precise and detailed meaning of the computing power of the correlations in the quantum cluster states is made. This study exposes a connection, arousing interest, between the infringement of the realistic models that are local and the computing power of the quantum entangled cluster states. 展开更多
关键词 Quantum computing computational Complexity Cluster States GATES
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Ferroelectric Liquid Crystal Gates and Optical Computing
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作者 SHIJian-jun SHIYon-ji 《Semiconductor Photonics and Technology》 CAS 1999年第3期179-185,共7页
The surface stabilized ferroelectric liquid crystal device configuration and ferroelectric liquid crystal gates are described.The liquid crystal electrooptical gates have numerous applications,including optical comput... The surface stabilized ferroelectric liquid crystal device configuration and ferroelectric liquid crystal gates are described.The liquid crystal electrooptical gates have numerous applications,including optical computation,optodigital circuits,and optical communication networks. 展开更多
关键词 Cellular Logic Liquid Crystal Electrooptical Gates Optical computation Optical Interconnection Network Optical Parallel Array Logic System CLC number:TP38 Document code:A
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Heralded hyper-CNOT gates for two-photon systems assisted by quantum scattering in waveguides
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作者 Jing-Xue Zhang Xue-Tong Sun +2 位作者 Lin-Xiong Wang Hai-Rui Wei Guo-Zhu Song 《Communications in Theoretical Physics》 SCIE CAS CSCD 2024年第11期76-84,共9页
Photonic hyper-parallel quantum gates play a critical role in high-capacity quantum communication and fast quantum computing.Here,based on photon scattering in onedimensional(1D)waveguides,we present some heralded sch... Photonic hyper-parallel quantum gates play a critical role in high-capacity quantum communication and fast quantum computing.Here,based on photon scattering in onedimensional(1D)waveguides,we present some heralded schemes for constructing four-qubit hyper-controlled-not(hyper-CNOT)gates in two-photon systems.The qubits are encoded on both the polarization and spatial-mode degrees of freedoms(DOFs)of the photons,which can simplify the quantum circuit and reduce the quantum resource consumption.In our schemes,the faulty scattering events between photons and emitters caused by system imperfections can be filtered out and discarded.That is,our protocols for hyper-CNOT gates work in a heralded way.Our calculations show that,with great progress in the emitter-waveguide systems,our photonic hyper-CNOT gates may be experimentally feasible. 展开更多
关键词 quantum computation hyper-CNOT gate waveguide QED
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Delayed-measurement one-way quantum computing on cloud quantum computer
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作者 Zhi-Peng Yang Yu-Ran Zhang +1 位作者 Fu-Li Li Heng Fan 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第9期125-131,共7页
One-way quantum computation focuses on initially generating an entangled cluster state followed by a sequence of measurements with classical communication of their individual outcomes.Recently,a delayed-measurement ap... One-way quantum computation focuses on initially generating an entangled cluster state followed by a sequence of measurements with classical communication of their individual outcomes.Recently,a delayed-measurement approach has been applied to replace classical communication of individual measurement outcomes.In this work,by considering the delayed-measurement approach,we demonstrate a modified one-way CNOT gate using the on-cloud superconducting quantum computing platform:Quafu.The modified protocol for one-way quantum computing requires only three qubits rather than the four used in the standard protocol.Since this modified cluster state decreases the number of physical qubits required to implement one-way computation,both the scalability and complexity of the computing process are improved.Compared to previous work,this modified one-way CNOT gate is superior to the standard one in both fidelity and resource requirements.We have also numerically compared the behavior of standard and modified methods in large-scale one-way quantum computing.Our results suggest that in a noisy intermediate-scale quantum(NISQ)era,the modified method shows a significant advantage for one-way quantum computation. 展开更多
关键词 measurement-based quantum computing quantum entanglement quantum gates
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Deep Learning Applied to Computational Mechanics:A Comprehensive Review,State of the Art,and the Classics 被引量:1
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作者 Loc Vu-Quoc Alexander Humer 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第11期1069-1343,共275页
Three recent breakthroughs due to AI in arts and science serve as motivation:An award winning digital image,protein folding,fast matrix multiplication.Many recent developments in artificial neural networks,particularl... Three recent breakthroughs due to AI in arts and science serve as motivation:An award winning digital image,protein folding,fast matrix multiplication.Many recent developments in artificial neural networks,particularly deep learning(DL),applied and relevant to computational mechanics(solid,fluids,finite-element technology)are reviewed in detail.Both hybrid and pure machine learning(ML)methods are discussed.Hybrid methods combine traditional PDE discretizations with ML methods either(1)to help model complex nonlinear constitutive relations,(2)to nonlinearly reduce the model order for efficient simulation(turbulence),or(3)to accelerate the simulation by predicting certain components in the traditional integration methods.Here,methods(1)and(2)relied on Long-Short-Term Memory(LSTM)architecture,with method(3)relying on convolutional neural networks.Pure ML methods to solve(nonlinear)PDEs are represented by Physics-Informed Neural network(PINN)methods,which could be combined with attention mechanism to address discontinuous solutions.Both LSTM and attention architectures,together with modern and generalized classic optimizers to include stochasticity for DL networks,are extensively reviewed.Kernel machines,including Gaussian processes,are provided to sufficient depth for more advanced works such as shallow networks with infinite width.Not only addressing experts,readers are assumed familiar with computational mechanics,but not with DL,whose concepts and applications are built up from the basics,aiming at bringing first-time learners quickly to the forefront of research.History and limitations of AI are recounted and discussed,with particular attention at pointing out misstatements or misconceptions of the classics,even in well-known references.Positioning and pointing control of a large-deformable beam is given as an example. 展开更多
关键词 Deep learning breakthroughs network architectures backpropagation stochastic optimization methods from classic to modern recurrent neural networks long short-term memory gated recurrent unit attention transformer kernel machines Gaussian processes libraries Physics-Informed Neural Networks state-of-the-art history limitations challenges Applications to computational mechanics Finite-element matrix integration improved Gauss quadrature Multiscale geomechanics fluid-filled porous media Fluid mechanics turbulence proper orthogonal decomposition Nonlinear-manifold model-order reduction autoencoder hyper-reduction using gappy data control of large deformable beam
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Recent progress in stimuli-responsive DNA-based logic gates:Design,working principles and biological applications
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作者 Ling Sum Liu Hoi Man Leung +1 位作者 Yuzhen Cai Pik Kwan Lo 《Smart Molecules》 2024年第1期25-43,共19页
Stimuli-responsive DNA-based logic gates have emerged as a promising field at the intersection of synthetic biology and nanotechnology.These gates exploit the unique properties of DNA molecules to perform programmable... Stimuli-responsive DNA-based logic gates have emerged as a promising field at the intersection of synthetic biology and nanotechnology.These gates exploit the unique properties of DNA molecules to perform programmable computational operations in response to specific stimuli.This review provides a comprehensive overview of recent advancements in the design,working principles,and applications of stimuli-responsive DNA-based logic gates.The progress made in developing various types of logic gates triggered by metal ions,pH,oligonucleotides,small molecules,proteins,and light is highlighted.The applications of these logic gates in imaging and biosensing,drug delivery,synthetic biology and molecular computing are discussed.This review underscores the significant contributions and future prospects of stimuli-responsive DNA-based logic gates in advancing the field of nanotechnology. 展开更多
关键词 DNA logic gates drug delivery IMAGING molecular computation STIMULI-RESPONSIVE
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新一代冠状动脉运动追踪冻结技术用于改善不同心率患者冠状动脉CT血管成像质量
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作者 安备 张卓璐 +4 位作者 刘卓 付玲 商旭 刘磊 程瑾 《中国介入影像与治疗学》 北大核心 2025年第2期131-135,共5页
目的观察新一代冠状动脉追踪冻结(NG SSF)技术用于改善不同心率(HR)患者冠状动脉CT血管成像(CCTA)质量的效果。方法回顾性分析利用256排CT机于1个心动周期内采集的164例CCTA数据,管电压分别为80、100及120 kV,以智能心电门控技术判断HR... 目的观察新一代冠状动脉追踪冻结(NG SSF)技术用于改善不同心率(HR)患者冠状动脉CT血管成像(CCTA)质量的效果。方法回顾性分析利用256排CT机于1个心动周期内采集的164例CCTA数据,管电压分别为80、100及120 kV,以智能心电门控技术判断HR并自动选择曝光期相:对HR≤65次/分者(低HR组)将曝光时间窗设在70%~80%R-R间期,65次/分<HR≤85次/分者(中等HR组)设在40%~80%R-R间期,HR>85次/分(高HR组)者设在40%~60%R-R间期;对3组图像分别以标准重建算法(STD)、第一代追踪冻结(SSF1)技术及NG SSF进行重建。以Likert量表对3种图像所示右冠状动脉(RCA)、左前降支(LAD)及左回旋支(LCX)各节段进行主观评分。结果低HR组NG SSF重建图像中的LAD中远段、RCA及LCX全段得分均高于STD,而NG SSF重建图像中的RCA中段及LAD远段得分高于SSF1重建图像(P均<0.05);中等HR组NG SSF重图像显示冠状动脉各节段的主观评分均高于STD及SSF1重建图像(P均<0.05);高HR组NG SSF重建图像显示冠状动脉各节段的主观评分均高于STD,显示RCA近远段、LAD中远段及LCX全段的主观评分均高于SSF1重建图像(P均<0.05)。结论利用NG SSF技术能有效提升不同HR患者前瞻性心电门控CCTA成像质量。 展开更多
关键词 冠状动脉疾病 CT血管成像 前瞻性心电门控扫描 追踪冻结技术
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