This paper demonstrates the intensity modulation characters of orthogonally polarized HeNe lasers with different optical feedback level generated by the variable reflectivity of external reflector. The modulation dept...This paper demonstrates the intensity modulation characters of orthogonally polarized HeNe lasers with different optical feedback level generated by the variable reflectivity of external reflector. The modulation depths of the orthogonally polarized frequencies are increased when the optical feedback level becomes strong. It also observes that the modulation amplitudes are different for different external cavity length. Based on the vectorial extension of Lamb＇s semi-classical theory, it finds that the calculations are consistent with the experimental results.展开更多
We present how residual intensity modulation(RIM) affects the performance of a resonator fiber optic gyro(R-FOG) through a sinusoidal wave phase modulation technique. The expression for the R-FOG system's demodula...We present how residual intensity modulation(RIM) affects the performance of a resonator fiber optic gyro(R-FOG) through a sinusoidal wave phase modulation technique. The expression for the R-FOG system's demodulation curve under RIM is obtained. Through numerical simulation with different RIM coefficients and modulation frequencies, we find that a zero deviation is induced by the RIM effect on the demodulation curve, and this zero deviation varies with the RIM coefficient and modulation frequency. The expression for the system error due to this zero deviation is derived. Simulation results show that the RIM-induced error varies with the RIM coefficient and modulation frequency. There also exists optimum values for the RIM coefficient and modulation frequency to totally eliminate the RIM-induced error, and the error increases as the RIM coefficient or modulation frequency deviates from its optimum value; however, in practical situations, these two parameters would not be exactly fixed but fluctuate from their respective optimum values, and a large system error is induced even if there exists a very small deviation of these two critical parameters from their optimum values. Simulation results indicate that the RIM-induced error should be considered when designing and evaluating an R-FOG system.展开更多
A designed visual geometry group(VGG)-based convolutional neural network(CNN)model with small computational cost and high accuracy is utilized to monitor pulse amplitude modulation-based intensity modulation and direc...A designed visual geometry group(VGG)-based convolutional neural network(CNN)model with small computational cost and high accuracy is utilized to monitor pulse amplitude modulation-based intensity modulation and direct detection channel performance using eye diagram measurements.Experimental results show that the proposed technique can achieve a high accuracy in jointly monitoring modulation format,probabilistic shaping,roll-off factor,baud rate,optical signal-to-noise ratio,and chromatic dispersion.The designed VGG-based CNN model outperforms the other four traditional machine-learning methods in different scenarios.Furthermore,the multitask learning model combined with MobileNet CNN is designed to improve the flexibility of the network.Compared with the designed VGG-based CNN,the MobileNet-based MTL does not need to train all the classes,and it can simultaneously monitor single parameter or multiple parameters without sacrificing accuracy,indicating great potential in various monitoring scenarios.展开更多
The characteristics of a conventional LiNbO3 intensity modulator made up of a Mach-Zehnder(MZ) type annealed proton exchange(APE) waveguide and coplanar waveguide(CPW) modulation electrode are presented. The APE waveg...The characteristics of a conventional LiNbO3 intensity modulator made up of a Mach-Zehnder(MZ) type annealed proton exchange(APE) waveguide and coplanar waveguide(CPW) modulation electrode are presented. The APE waveguide characteristics and their relations with process parameters are analyzed. At the same time, the electrical characteristics of modulation electrode, such as modulation voltage, microwave effective index associated with modulation bandwidth, characteristics impedance, are also investigated in detail.展开更多
The modulation depth, defined according to practical modulation results, which changes with the microwave power and its frequency, is significant for systems utilizing the frequency-shift characteristic of the LiNbO3 ...The modulation depth, defined according to practical modulation results, which changes with the microwave power and its frequency, is significant for systems utilizing the frequency-shift characteristic of the LiNbO3 waveguide Electro-Optic Intensity Modulator （EOIM）. By analyzing the impedance mismatch between the microwave source and the EOIM, the effective voltage applied to the RF port of the EOIM is deprived from the microwave power and its frequency. Associating with analyses of the phase velocity mismatch between the microwave and the optical wave, the theoretical modulation depth has been obtained, which is verified by experimental results. We provide a method to choose the appropriate modulation depth to optimize the desired sideband through proper transmission bias for the system based on the frequency-shift characteristic of the EOIM.展开更多
We experimentally demonstrate the transmission of discrete multi-tone(DMT)millimeter-wave(mm-wave)signals over a 1.2-km distance at the D-band(110–170 GHz)in a cost-effective intensity-modulation and direct-detection...We experimentally demonstrate the transmission of discrete multi-tone(DMT)millimeter-wave(mm-wave)signals over a 1.2-km distance at the D-band(110–170 GHz)in a cost-effective intensity-modulation and direct-detection(IM/DD)communication system.In the experiment,we successfully achieve the transmission of DMT-QPSK and DMT-16QAM mm-wave signals over multiple-input multiple-output(MIMO)links.After the 1.2-km free-space transmission,the bit error rate(BER)of the DMT-16QAM is below the 25%soft decision forward error correction(25%SD-FEC)threshold of 4×10^(-2),with a maximum net bit rate of 24.62 Gbit/s achieved in this system.展开更多
An adaptive dispersion estimation(ADE)is proposed to compensate dispersion and estimate the transfer function of the fiber channel with GerchbergSaxton(G-S)algorithm,using the stochastic gradient descent(SGD)method in...An adaptive dispersion estimation(ADE)is proposed to compensate dispersion and estimate the transfer function of the fiber channel with GerchbergSaxton(G-S)algorithm,using the stochastic gradient descent(SGD)method in the intensity-modulation and direct-detection(IM-DD)system,improving the tolerance of the algorithm to chromatic dispersion(CD).In order to address the divergence arising from the perturbation in the amplitude of the received signal caused by the filtering effect of the non-ideal channels,a channel-compensation equalizer(CCE)derived from the back-to-back(BTB)scenario is employed at the transmitter to make the amplitude of the received signal depicting the CD effect more accurately.The simulation results demonstrate the essentiality of CCE for the convergence and performance improvement of the G-S algorithm.Results show that it supports 112Gb/s four-level pulse amplitude modulation(PAM4)over 100 km standard single-mode fiber(SSMF)transmission under the 7%forward error correction(FEC)threshold of 3.8E-3.Besides,ADE improves the tolerance to wavelength drift from about 4 nm to 42 nm,and there is a better tolerance for fiber distance perturbation,indicating the G-S algorithm and its derived algorithms with the ADE scheme exhibit superior robustness to the perturbation in the system.展开更多
An analytic equation interpreting the intensity of ultrasound-modulated scattering light is derived, based on diffusion theory and previous explanations of the intensity modulation mechanism. Furthermore, an experimen...An analytic equation interpreting the intensity of ultrasound-modulated scattering light is derived, based on diffusion theory and previous explanations of the intensity modulation mechanism. Furthermore, an experiment of ultrasonic modulation of incoherent light in a scattering medium is developed. This analytical model agrees well with experimental results,which confirms the validity of the proposed intensity modulation mechanism. The model supplements the existing research on the ultrasonic modulation mechanism of scattering light.展开更多
Modulation techniques for light fidelity （Li-Fi） are reviewed in this paper. Li-Fi is the fully networked solution for nmltiple users that combines communication and illumination simultaneously. Light emitting diod...Modulation techniques for light fidelity （Li-Fi） are reviewed in this paper. Li-Fi is the fully networked solution for nmltiple users that combines communication and illumination simultaneously. Light emitting diodes （LEDs） are used in Li-Fi as visible light transmitters, therefore, only intensity modulated direct detected modulation techniques can be achieved. Single carrier modulation techniques are straightforward to be used in Li-Fi, however, computationally complex equalization processes are required in fre- quency selective Li-Fi channels. On the other hand, multiearrier modulation techniques offer a viable solution for Li-Fi in terms of power, spectral and computational efficiency. In particular, orthogonal frequency division multiplexing （OFDM） based modulation techniques offer a practical solution for Li-Fi, especially when direct current （DC） wander, and adaptive bit and power loading techniques are considered. Li-Fi modulation techniques need to also satisfy illumination requirements. Flickering avoidance and dimming control are considered in the variant modulation techniques presented. This paper surveys the suitable modulation techniques for Li-Fi including those which explore time, frequency and colour domains.展开更多
Evaluation of Gamma Index Analysis for Detecting Errors in Patient-specific Quality Assurance in Intensity Modulated Radiotherapy Taylan Tugrul1(1.Department of Radiation Oncology,Medicine Faculty of Van Yüzü...Evaluation of Gamma Index Analysis for Detecting Errors in Patient-specific Quality Assurance in Intensity Modulated Radiotherapy Taylan Tugrul1(1.Department of Radiation Oncology,Medicine Faculty of Van YüzüncüYıl University,Van,Turkey)Abstract:Quality assurance practices performed before treatment are believed to identify various potential errors.In this study,2-dimensional(2D)dosimetric results were analyzed by making some intentional mistakes in six different treatment plans.In this way,the detectability of errors was investigated.In all segments of all treatment plans,one of the multileaf collimators was kept fixed at different positions on the central axis.In addition to multileaf collimators error,gantry error was also examined in the study.The dose distribution results obtained by Treatment Planning System(TPS)were compared with those obtained by the 2D array device,both as local calculation and global calculation methods,using the gamma analysis method.When the results are examined in the case where the Multi-leaf collimators(MLC)is fixed at the 1 cm position.展开更多
Subcarrier intensity modulation with direet detection is a modulatiou/detection technique tbr optical wireless communication systems, where a pre-modulated and properly biased radio frequency signal is modulated on th...Subcarrier intensity modulation with direet detection is a modulatiou/detection technique tbr optical wireless communication systems, where a pre-modulated and properly biased radio frequency signal is modulated on the intensity of the optical carrier. The most important benefits of subcarrier intensity modulation are as follows： 1） it does not provide irreducible error floor like the conventional on-off keying intensity modulation with a fixed detection threshold; 2） it provides improved spectral efficiency and supports higher order modulation schemes; and 3） it has much less implementation complexity compared to coherent optical wireless communications with heterodyne or homodyne detection. In this paper, we present an up-to-date review of subcarrier intensity modulated optical wireless communication systems. We survey the error rate and outage performance of subcarrier intensity modulations in the atmospheric turbulence channels considering different modulation and coding schemes. We also explore different contemporary atmospheric turbulence fading mitigation solutions that can be employed for subcarrier intensity modulation. These solutions include diversity combining, adaptive transmission, relay assisted transmission, multiple-subcarrier intensity modulations, and optical orthogonal frequency division multiplexing. Moreover, we review the performance of subcarrier intensity modulations due to the pointing error and synchronization error.展开更多
AIM:To evaluate impact of radiation therapy dose escalation through intensity modulated radiation therapy with simultaneous integrated boost(IMRT-SIB).METHODS:We retrospectively reviewed the patients who underwent fou...AIM:To evaluate impact of radiation therapy dose escalation through intensity modulated radiation therapy with simultaneous integrated boost(IMRT-SIB).METHODS:We retrospectively reviewed the patients who underwent four-dimensional-based IMRT-SIBbased neoadjuvant chemoradiation protocol.During the concurrent chemoradiation therapy,radiation therapy was through IMRT-SIB delivered in 28 consecutive daily fractions with total radiation doses of 56 Gy to tumor and 5040 Gy dose-painted to clinical tumor volume,with a regimen at the discretion of the treating medical oncologist.This was followed by surgical tumor resection.We analyzed pathological completion response(p CR)rates its relationship with overall survival and event-freesurvival.RESULTS:Seventeen patients underwent dose escalation with the IMRT-SIB protocol between 2007 and 2014 and their records were available for analysis.Among the IMRT-SIB-treated patients,the toxicity appeared mild,the most common side effects were grade 1-3 esophagitis(46%)and pneumonitis(11.7%).There were no cardiac events.The Ro resection rate was 94%(n=16),the p CR rate was 47%(n=8),and the postoperative morbidity was zero.There was one mediastinal failure found,one patient had local failure at the anastomosis site,and the majority of failures were distant in the lung or bone.The 3-year diseasefree survival and overall survival rates were 41%(n=7)and 53%(n=9),respectively.CONCLUSION:The dose escalation through IMRT-SIB in the chemoradiation regimen seems responsible for down-staging the distal esophageal with well-tolerated complications.展开更多
AIM:To study the leakage-penumbra(LP)effect with a proposed correction method for the step-and-shoot intensity modulated radiation therapy(IMRT).METHODS:Leakage-penumbra dose profiles from 10 randomly selected prostat...AIM:To study the leakage-penumbra(LP)effect with a proposed correction method for the step-and-shoot intensity modulated radiation therapy(IMRT).METHODS:Leakage-penumbra dose profiles from 10 randomly selected prostate IMRT plans were studied.The IMRT plans were delivered by a Varian 21 EX linear accelerator equipped with a 120-leaf multileaf collimator(MLC).For each treatment plan created by the Pinnacle3 treatment planning system,a 3-dimensional LP dose distribution generated by 5 coplanar photon beams,starting from 0o with equal separation of 72 o,was investigated.For each photon beam used in the stepand-shoot IMRT plans,the first beam segment was set to have the largest area in the MLC leaf-sequencing,and was equal to the planning target volume(PTV).The overshoot effect(OSE)and the segment positional errors were measured using a solid water phantom with Kodak(TL and X-OMAT V)radiographic films.Film dosimetric analysis and calibration were carried out using a film scanner(Vidar VXR-16).The LP dose profiles were determined by eliminating the OSE and segment positional errors with specific individual irradiations.RESULTS:A non-uniformly distributed leaf LP dose ranging from 3%to 5%of the beam dose was measured in clinical IMRT beams.An overdose at the gap between neighboring segments,represented as dose peaks of up to 10%of the total BP,was measured.The LP effect increased the dose to the PTV and surrounding critical tissues.In addition,the effectdepends on the number of beams and segments for each beam.Segment positional error was less than the maximum tolerance of 1 mm under a dose rate of 600 monitor units per minute in the treatment plans.The OSE varying with the dose rate was observed in all photon beams,and the effect increased from 1 to 1.3 Gy per treatment of the rectal intersection.As the dosimetric impacts from the LP effect and OSE may increase the rectal post-radiation effects,a correction of LP was proposed and demonstrated for the central beam profile for one of the planned beams.CONCLUSION:We concluded that the measured dosimetric impact of the LP dose inaccuracy from photon beam segment in step-and-shoot IMRT can be corrected.展开更多
In this paper, we have evaluated a bidirectional wavelength division multiplexing passive optical network(WDM-PON) employing intensity modulated/direct detection optical orthogonal frequency division multiplexing(IM/D...In this paper, we have evaluated a bidirectional wavelength division multiplexing passive optical network(WDM-PON) employing intensity modulated/direct detection optical orthogonal frequency division multiplexing(IM/DD-OFDM). The proposed system employs 100 Gbit/s 16 quadrature amplitude modulation(16-QAM) downstream and 5 Gbit/s on-off keying(OOK) upstream wavelengths, respectively. The proposed system is considered low-cost as non-coherent IM/DD OFDM technology and a simple reflective semiconductor optical amplifier(RSOA) colorless transmitter are employed and no dispersion compensating fiber(DCF) is needed. Based on the bit error rate(BER) results of WDM signals, the proposed WDM-PON system can achieve up to 1.6 Tbit/s(100 Gbit/s/λ × 16 wavelengths) downstream transmission over a 30 km single mode fiber(SMF).展开更多
High-speed and wide-band LiNbO3 waveguide electro-optic intensity modulator has drawn great attention in the field of optical fiber communication and sensor. This paper reports the research results on the measurement ...High-speed and wide-band LiNbO3 waveguide electro-optic intensity modulator has drawn great attention in the field of optical fiber communication and sensor. This paper reports the research results on the measurement of frequency shift characteristics of Mach-Zehnder electro-optic intensity modulator. Two measurement methods of frequency shift characteristics for high and low frequency modulations are studied in theory and experiment and demonstrate different results. The realization of a multi-wavelength optical source based on Mach-Zehnder electro-optic intensity modulator has been introduced. The technique to reach the maximum intensity for interesting shift frequency, particularly for heterodyne detection of Brillouin distributed optical fiber sensing, has been given.展开更多
We propose a novel light intensity modulator based on magnetic fluid and liquid crystal（LC） filled photonic crystal fibers（PCFs）. The influences of electric and magnetic fields on the transmission intensity are th...We propose a novel light intensity modulator based on magnetic fluid and liquid crystal（LC） filled photonic crystal fibers（PCFs）. The influences of electric and magnetic fields on the transmission intensity are theoretically and experimentally analyzed and investigated. Both the electric and magnetic fields can manipulate the molecular arrangement of LC to array a certain angle without changing the refractive index of the LC. Therefore, light loss in the PCF varies with the electric and magnetic fields whereas the peak wavelengths remain constant. The experimental results show that the transmission intensity decreases with the increase of the electric and magnetic fields. The cut-off electric field is 0.899 V/um at 20 Hz and the cut-off magnetic field is 195 m T. This simple and compacted optical modulator will have a great prospect in sensing applications.展开更多
Objective:Serum prostate specific antigen(PSA)is commonly used to evaluate treatment response after definitive radiation therapy(RT).However,PSA levels can temporarily rise without a clear reason,termed“PSA bounce”,...Objective:Serum prostate specific antigen(PSA)is commonly used to evaluate treatment response after definitive radiation therapy(RT).However,PSA levels can temporarily rise without a clear reason,termed“PSA bounce”,and often engender great anxiety for both patients and physicians.The present study aimed to determine the prevalence and factors that predict“PSA bounce”after intensity-modulated radiation therapy(IMRT),and the relevance to biochemical failure and cancer recurrence in an Asian population.Methods:We retrospectively reviewed 206 patients who received IMRT for prostate cancer from 2004 to 2012 in the National Cancer Centre Singapore.These patients were followed up with regular PSA monitoring.We defined“PSA bounce”as a rise of 0.1 ng/mL,followed by two consecutive falls.Patients with biochemical failure(PSA nadir t 2 ng/mL)were further evaluated for cancer recurrence.Results:Sixty-one patients(29.6%)experienced“PSA bounce”,at a median time of 16 months and lasted for 12 months.Age remained the most consistent predictor of the incidence,duration and extent of“PSA bounce”.Other contributory factors included baseline PSA,Gleason score and PSA nadir.Hormonal therapy and prostate volume did not affect this phenomenon.Sixteen patients(7.8%)developed biochemical recurrence,at median time of 32 months,of which 11 were confirmed to have metastatic disease.The median follow-up time was 71 months.展开更多
Objective: To evaluate the clinical effects of concurrent and sequential therapy for middle and advanced stage non-small cell lung cancer (NSCLC) useing IMRT combined with NP regimen chemotherapy. Methods: Eighty pati...Objective: To evaluate the clinical effects of concurrent and sequential therapy for middle and advanced stage non-small cell lung cancer (NSCLC) useing IMRT combined with NP regimen chemotherapy. Methods: Eighty patients with middle and advanced stage NSCLC were randomized into two groups. Forty patients were underwent sequential therapy and other 40 patients were underwent concurrent therapy. IMRT was used in radiotherapy and NP regimen of vinorelbine+cispatin (NP) was used in chemotherapy. Results: (1) The overall response (CR+PR) rate was 75% in concurrent group and 45% in sequential group (P<0.05); (2) The treatment courses were 84 days and 140 days for concurrent group and sequential group respectively (P<0.05); (3) One-year survival rate in concurrent group was 72.4% and 52.3% in sequential group respectively; (4) The toxic effects can be tolerable by all of patients. Conclusion: The concurrent chemo-radiotherapy has better overall re- sponse, one-year survival rate and shorter treatment course than the sequential chemo-radiotherapy, so it is a better method for the treatment of middle and advanced stage NSCLC, but the long term survival rate will be studied.展开更多
Objective: The purpose of this study was to investigate the impact of intensity modulated radiotherapy (IMRT) on surface doses for brain, abdomen and pelvis deep located tumors treated with 6 MV photon and to evaluate...Objective: The purpose of this study was to investigate the impact of intensity modulated radiotherapy (IMRT) on surface doses for brain, abdomen and pelvis deep located tumors treated with 6 MV photon and to evaluate the skin dose calculation accuracy of the XIO 4.04 treatment planning system. Methods: More investigations for the influences of IMRT on skin doses would increase its applications for many treatment sites. Measuring skin doses in real treatment situations would reduce the uncertainty of skin dose prediction. In this work a pediatric human phantom was covered by a layer of 1 mm bolus at three treatment sites and thermoluminescent dosimeter (TLD) chips were inserted into the bolus at each treatment site before CT scan. Two different treatment plans [three-dimensional conformal radiation therapy (3DCRT) and IMRT] for each treatment sites were performed on XIO 4.04 treatment planning system using superposition algorism. Results: The results showed that the surface doses for 3DCRT were higher than the surface doses in IMRT by 1.6%, 2.5% and 3.2% for brain, abdomen and pelvis sites respectively. There was good agreement between measured and calculated surface doses, where the calculated surface dose was 15.5% for brain tumor calculated with 3DCRT whereas the measured surface dose was 12.1%. For abdomen site the calculated surface dose for IMRT treatment plan was 16.5% whereas the measured surface dose was 12.6%. Conclusion: The skin dose in IMRT for deep seated tumors is lower than that in 3DCRT which is another advantage for the IMRT. The TLD readings showed that the difference between the calculated and measured point dose is negligible. The superposition calculation algorism of the XIO 4.04 treatment planning system modeled the superficial dose well.展开更多
Objective:This study was to compare 5 field conformal technique to the intensity modulated radiotherapy (IMRT) 8 fields technique in boosting locally advanced cancer cervix cases after external beam radiotherapy with ...Objective:This study was to compare 5 field conformal technique to the intensity modulated radiotherapy (IMRT) 8 fields technique in boosting locally advanced cancer cervix cases after external beam radiotherapy with respect to target volume coverage and dose to normal tissues. Methods:We conducted a single institutional comparative dosimetric analysis of 10 patients with cancer cervix who was presented to radiotherapy department in National Cancer Institute, Cairo in period between June 2012 to September 2012 and received a CRT boost in the place of planned brachytherapy after large field pelvic radiotherapy (PRT) with concurrent chemotherapy were retrospectively identified. All tumors were situated in the low central pelvis. Two plans were done for every patient; one using the 8 fields IMRT and the second one using 5 fields' 3DCRT the two techniques were then compared using dose volume histogram (DVH) analysis for the PTV, bladder, rectum and both femoral heads. Results:Comparing different DVHs, it was found that the planning target volume (PTV) was adequately covered in both plans while it was demonstrates that the 8 fields IMRT technique carried less doses reaching OARs (rectum, bladder, both femoral heads). Conclusion:From the present study, it is concluded that IMRT technique spared more efficiently OARs than CRT technique but both techniques covered the PTV adequately so whenever possible IMRT technique should be used.展开更多
基金Project supported by the State Key Program of National Natural Science of China (Grant No 60438010)
文摘This paper demonstrates the intensity modulation characters of orthogonally polarized HeNe lasers with different optical feedback level generated by the variable reflectivity of external reflector. The modulation depths of the orthogonally polarized frequencies are increased when the optical feedback level becomes strong. It also observes that the modulation amplitudes are different for different external cavity length. Based on the vectorial extension of Lamb＇s semi-classical theory, it finds that the calculations are consistent with the experimental results.
基金Project supported by the Zhejiang Provincial Natural ScienceFoundation of China(No.LQ13F050001)
文摘We present how residual intensity modulation(RIM) affects the performance of a resonator fiber optic gyro(R-FOG) through a sinusoidal wave phase modulation technique. The expression for the R-FOG system's demodulation curve under RIM is obtained. Through numerical simulation with different RIM coefficients and modulation frequencies, we find that a zero deviation is induced by the RIM effect on the demodulation curve, and this zero deviation varies with the RIM coefficient and modulation frequency. The expression for the system error due to this zero deviation is derived. Simulation results show that the RIM-induced error varies with the RIM coefficient and modulation frequency. There also exists optimum values for the RIM coefficient and modulation frequency to totally eliminate the RIM-induced error, and the error increases as the RIM coefficient or modulation frequency deviates from its optimum value; however, in practical situations, these two parameters would not be exactly fixed but fluctuate from their respective optimum values, and a large system error is induced even if there exists a very small deviation of these two critical parameters from their optimum values. Simulation results indicate that the RIM-induced error should be considered when designing and evaluating an R-FOG system.
基金supported by the National Key Research and Development Program of China (Grant No.2019YFB1803700)the Key Technologies Research and Development Program of Tianjin (Grant No.20YFZCGX00440).
文摘A designed visual geometry group(VGG)-based convolutional neural network(CNN)model with small computational cost and high accuracy is utilized to monitor pulse amplitude modulation-based intensity modulation and direct detection channel performance using eye diagram measurements.Experimental results show that the proposed technique can achieve a high accuracy in jointly monitoring modulation format,probabilistic shaping,roll-off factor,baud rate,optical signal-to-noise ratio,and chromatic dispersion.The designed VGG-based CNN model outperforms the other four traditional machine-learning methods in different scenarios.Furthermore,the multitask learning model combined with MobileNet CNN is designed to improve the flexibility of the network.Compared with the designed VGG-based CNN,the MobileNet-based MTL does not need to train all the classes,and it can simultaneously monitor single parameter or multiple parameters without sacrificing accuracy,indicating great potential in various monitoring scenarios.
文摘The characteristics of a conventional LiNbO3 intensity modulator made up of a Mach-Zehnder(MZ) type annealed proton exchange(APE) waveguide and coplanar waveguide(CPW) modulation electrode are presented. The APE waveguide characteristics and their relations with process parameters are analyzed. At the same time, the electrical characteristics of modulation electrode, such as modulation voltage, microwave effective index associated with modulation bandwidth, characteristics impedance, are also investigated in detail.
基金supported by Program for New Century Excellent Talents in University(No.NCET-06-0925)
文摘The modulation depth, defined according to practical modulation results, which changes with the microwave power and its frequency, is significant for systems utilizing the frequency-shift characteristic of the LiNbO3 waveguide Electro-Optic Intensity Modulator （EOIM）. By analyzing the impedance mismatch between the microwave source and the EOIM, the effective voltage applied to the RF port of the EOIM is deprived from the microwave power and its frequency. Associating with analyses of the phase velocity mismatch between the microwave and the optical wave, the theoretical modulation depth has been obtained, which is verified by experimental results. We provide a method to choose the appropriate modulation depth to optimize the desired sideband through proper transmission bias for the system based on the frequency-shift characteristic of the EOIM.
基金supported by the National Key R&D Program of China(No.2023YFB2905600)the National Natural Science Foundation of China(Nos.61935005,62127802,62331004,62305067)the Key Project of Jiangsu Province of China(No.BE2023001-4)。
文摘We experimentally demonstrate the transmission of discrete multi-tone(DMT)millimeter-wave(mm-wave)signals over a 1.2-km distance at the D-band(110–170 GHz)in a cost-effective intensity-modulation and direct-detection(IM/DD)communication system.In the experiment,we successfully achieve the transmission of DMT-QPSK and DMT-16QAM mm-wave signals over multiple-input multiple-output(MIMO)links.After the 1.2-km free-space transmission,the bit error rate(BER)of the DMT-16QAM is below the 25%soft decision forward error correction(25%SD-FEC)threshold of 4×10^(-2),with a maximum net bit rate of 24.62 Gbit/s achieved in this system.
基金funded by the National Natural Science Foundation of China NSFC,U22A2005 and 62201033theYoung Elite Scientists Sponsorship Program of CIC 2021QNRC001。
文摘An adaptive dispersion estimation(ADE)is proposed to compensate dispersion and estimate the transfer function of the fiber channel with GerchbergSaxton(G-S)algorithm,using the stochastic gradient descent(SGD)method in the intensity-modulation and direct-detection(IM-DD)system,improving the tolerance of the algorithm to chromatic dispersion(CD).In order to address the divergence arising from the perturbation in the amplitude of the received signal caused by the filtering effect of the non-ideal channels,a channel-compensation equalizer(CCE)derived from the back-to-back(BTB)scenario is employed at the transmitter to make the amplitude of the received signal depicting the CD effect more accurately.The simulation results demonstrate the essentiality of CCE for the convergence and performance improvement of the G-S algorithm.Results show that it supports 112Gb/s four-level pulse amplitude modulation(PAM4)over 100 km standard single-mode fiber(SSMF)transmission under the 7%forward error correction(FEC)threshold of 3.8E-3.Besides,ADE improves the tolerance to wavelength drift from about 4 nm to 42 nm,and there is a better tolerance for fiber distance perturbation,indicating the G-S algorithm and its derived algorithms with the ADE scheme exhibit superior robustness to the perturbation in the system.
基金Project supported by the National Natural Science Foundation of China(Grant No.61178089)the Key Program of Science and Technology of Fujian Province,China(Grant No.2011Y0019)the Educational Department of Fujian Province,China(Grant No.JA13074)
文摘An analytic equation interpreting the intensity of ultrasound-modulated scattering light is derived, based on diffusion theory and previous explanations of the intensity modulation mechanism. Furthermore, an experiment of ultrasonic modulation of incoherent light in a scattering medium is developed. This analytical model agrees well with experimental results,which confirms the validity of the proposed intensity modulation mechanism. The model supplements the existing research on the ultrasonic modulation mechanism of scattering light.
基金support by the UK Engineering and Physical Sciences Research Council(EPSRC)under Grants EP/K008757/1 and EP/M506515/1
文摘Modulation techniques for light fidelity （Li-Fi） are reviewed in this paper. Li-Fi is the fully networked solution for nmltiple users that combines communication and illumination simultaneously. Light emitting diodes （LEDs） are used in Li-Fi as visible light transmitters, therefore, only intensity modulated direct detected modulation techniques can be achieved. Single carrier modulation techniques are straightforward to be used in Li-Fi, however, computationally complex equalization processes are required in fre- quency selective Li-Fi channels. On the other hand, multiearrier modulation techniques offer a viable solution for Li-Fi in terms of power, spectral and computational efficiency. In particular, orthogonal frequency division multiplexing （OFDM） based modulation techniques offer a practical solution for Li-Fi, especially when direct current （DC） wander, and adaptive bit and power loading techniques are considered. Li-Fi modulation techniques need to also satisfy illumination requirements. Flickering avoidance and dimming control are considered in the variant modulation techniques presented. This paper surveys the suitable modulation techniques for Li-Fi including those which explore time, frequency and colour domains.
文摘Evaluation of Gamma Index Analysis for Detecting Errors in Patient-specific Quality Assurance in Intensity Modulated Radiotherapy Taylan Tugrul1(1.Department of Radiation Oncology,Medicine Faculty of Van YüzüncüYıl University,Van,Turkey)Abstract:Quality assurance practices performed before treatment are believed to identify various potential errors.In this study,2-dimensional(2D)dosimetric results were analyzed by making some intentional mistakes in six different treatment plans.In this way,the detectability of errors was investigated.In all segments of all treatment plans,one of the multileaf collimators was kept fixed at different positions on the central axis.In addition to multileaf collimators error,gantry error was also examined in the study.The dose distribution results obtained by Treatment Planning System(TPS)were compared with those obtained by the 2D array device,both as local calculation and global calculation methods,using the gamma analysis method.When the results are examined in the case where the Multi-leaf collimators(MLC)is fixed at the 1 cm position.
文摘Subcarrier intensity modulation with direet detection is a modulatiou/detection technique tbr optical wireless communication systems, where a pre-modulated and properly biased radio frequency signal is modulated on the intensity of the optical carrier. The most important benefits of subcarrier intensity modulation are as follows： 1） it does not provide irreducible error floor like the conventional on-off keying intensity modulation with a fixed detection threshold; 2） it provides improved spectral efficiency and supports higher order modulation schemes; and 3） it has much less implementation complexity compared to coherent optical wireless communications with heterodyne or homodyne detection. In this paper, we present an up-to-date review of subcarrier intensity modulated optical wireless communication systems. We survey the error rate and outage performance of subcarrier intensity modulations in the atmospheric turbulence channels considering different modulation and coding schemes. We also explore different contemporary atmospheric turbulence fading mitigation solutions that can be employed for subcarrier intensity modulation. These solutions include diversity combining, adaptive transmission, relay assisted transmission, multiple-subcarrier intensity modulations, and optical orthogonal frequency division multiplexing. Moreover, we review the performance of subcarrier intensity modulations due to the pointing error and synchronization error.
文摘AIM:To evaluate impact of radiation therapy dose escalation through intensity modulated radiation therapy with simultaneous integrated boost(IMRT-SIB).METHODS:We retrospectively reviewed the patients who underwent four-dimensional-based IMRT-SIBbased neoadjuvant chemoradiation protocol.During the concurrent chemoradiation therapy,radiation therapy was through IMRT-SIB delivered in 28 consecutive daily fractions with total radiation doses of 56 Gy to tumor and 5040 Gy dose-painted to clinical tumor volume,with a regimen at the discretion of the treating medical oncologist.This was followed by surgical tumor resection.We analyzed pathological completion response(p CR)rates its relationship with overall survival and event-freesurvival.RESULTS:Seventeen patients underwent dose escalation with the IMRT-SIB protocol between 2007 and 2014 and their records were available for analysis.Among the IMRT-SIB-treated patients,the toxicity appeared mild,the most common side effects were grade 1-3 esophagitis(46%)and pneumonitis(11.7%).There were no cardiac events.The Ro resection rate was 94%(n=16),the p CR rate was 47%(n=8),and the postoperative morbidity was zero.There was one mediastinal failure found,one patient had local failure at the anastomosis site,and the majority of failures were distant in the lung or bone.The 3-year diseasefree survival and overall survival rates were 41%(n=7)and 53%(n=9),respectively.CONCLUSION:The dose escalation through IMRT-SIB in the chemoradiation regimen seems responsible for down-staging the distal esophageal with well-tolerated complications.
文摘AIM:To study the leakage-penumbra(LP)effect with a proposed correction method for the step-and-shoot intensity modulated radiation therapy(IMRT).METHODS:Leakage-penumbra dose profiles from 10 randomly selected prostate IMRT plans were studied.The IMRT plans were delivered by a Varian 21 EX linear accelerator equipped with a 120-leaf multileaf collimator(MLC).For each treatment plan created by the Pinnacle3 treatment planning system,a 3-dimensional LP dose distribution generated by 5 coplanar photon beams,starting from 0o with equal separation of 72 o,was investigated.For each photon beam used in the stepand-shoot IMRT plans,the first beam segment was set to have the largest area in the MLC leaf-sequencing,and was equal to the planning target volume(PTV).The overshoot effect(OSE)and the segment positional errors were measured using a solid water phantom with Kodak(TL and X-OMAT V)radiographic films.Film dosimetric analysis and calibration were carried out using a film scanner(Vidar VXR-16).The LP dose profiles were determined by eliminating the OSE and segment positional errors with specific individual irradiations.RESULTS:A non-uniformly distributed leaf LP dose ranging from 3%to 5%of the beam dose was measured in clinical IMRT beams.An overdose at the gap between neighboring segments,represented as dose peaks of up to 10%of the total BP,was measured.The LP effect increased the dose to the PTV and surrounding critical tissues.In addition,the effectdepends on the number of beams and segments for each beam.Segment positional error was less than the maximum tolerance of 1 mm under a dose rate of 600 monitor units per minute in the treatment plans.The OSE varying with the dose rate was observed in all photon beams,and the effect increased from 1 to 1.3 Gy per treatment of the rectal intersection.As the dosimetric impacts from the LP effect and OSE may increase the rectal post-radiation effects,a correction of LP was proposed and demonstrated for the central beam profile for one of the planned beams.CONCLUSION:We concluded that the measured dosimetric impact of the LP dose inaccuracy from photon beam segment in step-and-shoot IMRT can be corrected.
基金supported by the Erciyes University Scientific Research Projects Coordination Unit (No.FDK-2019-8750)。
文摘In this paper, we have evaluated a bidirectional wavelength division multiplexing passive optical network(WDM-PON) employing intensity modulated/direct detection optical orthogonal frequency division multiplexing(IM/DD-OFDM). The proposed system employs 100 Gbit/s 16 quadrature amplitude modulation(16-QAM) downstream and 5 Gbit/s on-off keying(OOK) upstream wavelengths, respectively. The proposed system is considered low-cost as non-coherent IM/DD OFDM technology and a simple reflective semiconductor optical amplifier(RSOA) colorless transmitter are employed and no dispersion compensating fiber(DCF) is needed. Based on the bit error rate(BER) results of WDM signals, the proposed WDM-PON system can achieve up to 1.6 Tbit/s(100 Gbit/s/λ × 16 wavelengths) downstream transmission over a 30 km single mode fiber(SMF).
基金supported by Program for New Century Excellent Talents in University under Grand No. NCET-06-0925.
文摘High-speed and wide-band LiNbO3 waveguide electro-optic intensity modulator has drawn great attention in the field of optical fiber communication and sensor. This paper reports the research results on the measurement of frequency shift characteristics of Mach-Zehnder electro-optic intensity modulator. Two measurement methods of frequency shift characteristics for high and low frequency modulations are studied in theory and experiment and demonstrate different results. The realization of a multi-wavelength optical source based on Mach-Zehnder electro-optic intensity modulator has been introduced. The technique to reach the maximum intensity for interesting shift frequency, particularly for heterodyne detection of Brillouin distributed optical fiber sensing, has been given.
基金Supported by the Joint Research Fund in Astronomy under Cooperative Agreement between the National Natural Science Foundation of China and Chinese Academy of Sciences under Grant No U1531102the Fundamental Research Funds for the Central Universities under Grant No HEUCF181116the National Natural Science Foundation of China under Grant Nos61107059,61077047 and 11264001
文摘We propose a novel light intensity modulator based on magnetic fluid and liquid crystal（LC） filled photonic crystal fibers（PCFs）. The influences of electric and magnetic fields on the transmission intensity are theoretically and experimentally analyzed and investigated. Both the electric and magnetic fields can manipulate the molecular arrangement of LC to array a certain angle without changing the refractive index of the LC. Therefore, light loss in the PCF varies with the electric and magnetic fields whereas the peak wavelengths remain constant. The experimental results show that the transmission intensity decreases with the increase of the electric and magnetic fields. The cut-off electric field is 0.899 V/um at 20 Hz and the cut-off magnetic field is 195 m T. This simple and compacted optical modulator will have a great prospect in sensing applications.
文摘Objective:Serum prostate specific antigen(PSA)is commonly used to evaluate treatment response after definitive radiation therapy(RT).However,PSA levels can temporarily rise without a clear reason,termed“PSA bounce”,and often engender great anxiety for both patients and physicians.The present study aimed to determine the prevalence and factors that predict“PSA bounce”after intensity-modulated radiation therapy(IMRT),and the relevance to biochemical failure and cancer recurrence in an Asian population.Methods:We retrospectively reviewed 206 patients who received IMRT for prostate cancer from 2004 to 2012 in the National Cancer Centre Singapore.These patients were followed up with regular PSA monitoring.We defined“PSA bounce”as a rise of 0.1 ng/mL,followed by two consecutive falls.Patients with biochemical failure(PSA nadir t 2 ng/mL)were further evaluated for cancer recurrence.Results:Sixty-one patients(29.6%)experienced“PSA bounce”,at a median time of 16 months and lasted for 12 months.Age remained the most consistent predictor of the incidence,duration and extent of“PSA bounce”.Other contributory factors included baseline PSA,Gleason score and PSA nadir.Hormonal therapy and prostate volume did not affect this phenomenon.Sixteen patients(7.8%)developed biochemical recurrence,at median time of 32 months,of which 11 were confirmed to have metastatic disease.The median follow-up time was 71 months.
基金Supported by a grant from Health Bureau of Lianyungang City’s Fund Program (No. 05051).
文摘Objective: To evaluate the clinical effects of concurrent and sequential therapy for middle and advanced stage non-small cell lung cancer (NSCLC) useing IMRT combined with NP regimen chemotherapy. Methods: Eighty patients with middle and advanced stage NSCLC were randomized into two groups. Forty patients were underwent sequential therapy and other 40 patients were underwent concurrent therapy. IMRT was used in radiotherapy and NP regimen of vinorelbine+cispatin (NP) was used in chemotherapy. Results: (1) The overall response (CR+PR) rate was 75% in concurrent group and 45% in sequential group (P<0.05); (2) The treatment courses were 84 days and 140 days for concurrent group and sequential group respectively (P<0.05); (3) One-year survival rate in concurrent group was 72.4% and 52.3% in sequential group respectively; (4) The toxic effects can be tolerable by all of patients. Conclusion: The concurrent chemo-radiotherapy has better overall re- sponse, one-year survival rate and shorter treatment course than the sequential chemo-radiotherapy, so it is a better method for the treatment of middle and advanced stage NSCLC, but the long term survival rate will be studied.
文摘Objective: The purpose of this study was to investigate the impact of intensity modulated radiotherapy (IMRT) on surface doses for brain, abdomen and pelvis deep located tumors treated with 6 MV photon and to evaluate the skin dose calculation accuracy of the XIO 4.04 treatment planning system. Methods: More investigations for the influences of IMRT on skin doses would increase its applications for many treatment sites. Measuring skin doses in real treatment situations would reduce the uncertainty of skin dose prediction. In this work a pediatric human phantom was covered by a layer of 1 mm bolus at three treatment sites and thermoluminescent dosimeter (TLD) chips were inserted into the bolus at each treatment site before CT scan. Two different treatment plans [three-dimensional conformal radiation therapy (3DCRT) and IMRT] for each treatment sites were performed on XIO 4.04 treatment planning system using superposition algorism. Results: The results showed that the surface doses for 3DCRT were higher than the surface doses in IMRT by 1.6%, 2.5% and 3.2% for brain, abdomen and pelvis sites respectively. There was good agreement between measured and calculated surface doses, where the calculated surface dose was 15.5% for brain tumor calculated with 3DCRT whereas the measured surface dose was 12.1%. For abdomen site the calculated surface dose for IMRT treatment plan was 16.5% whereas the measured surface dose was 12.6%. Conclusion: The skin dose in IMRT for deep seated tumors is lower than that in 3DCRT which is another advantage for the IMRT. The TLD readings showed that the difference between the calculated and measured point dose is negligible. The superposition calculation algorism of the XIO 4.04 treatment planning system modeled the superficial dose well.
文摘Objective:This study was to compare 5 field conformal technique to the intensity modulated radiotherapy (IMRT) 8 fields technique in boosting locally advanced cancer cervix cases after external beam radiotherapy with respect to target volume coverage and dose to normal tissues. Methods:We conducted a single institutional comparative dosimetric analysis of 10 patients with cancer cervix who was presented to radiotherapy department in National Cancer Institute, Cairo in period between June 2012 to September 2012 and received a CRT boost in the place of planned brachytherapy after large field pelvic radiotherapy (PRT) with concurrent chemotherapy were retrospectively identified. All tumors were situated in the low central pelvis. Two plans were done for every patient; one using the 8 fields IMRT and the second one using 5 fields' 3DCRT the two techniques were then compared using dose volume histogram (DVH) analysis for the PTV, bladder, rectum and both femoral heads. Results:Comparing different DVHs, it was found that the planning target volume (PTV) was adequately covered in both plans while it was demonstrates that the 8 fields IMRT technique carried less doses reaching OARs (rectum, bladder, both femoral heads). Conclusion:From the present study, it is concluded that IMRT technique spared more efficiently OARs than CRT technique but both techniques covered the PTV adequately so whenever possible IMRT technique should be used.
