目的:观察微创超薄与计算机辅助设计与制造(Computer Aided Design/Computer Aided Manufacturing,CAD/CAM)全瓷贴面修复前牙间隙的美学效果及对口腔菌群微环境的影响。方法:选取笔者医院2023年2月-2025年2月收治的94例(共135颗患牙)前...目的:观察微创超薄与计算机辅助设计与制造(Computer Aided Design/Computer Aided Manufacturing,CAD/CAM)全瓷贴面修复前牙间隙的美学效果及对口腔菌群微环境的影响。方法:选取笔者医院2023年2月-2025年2月收治的94例(共135颗患牙)前牙间隙患者为研究对象,采用随机数字表法分为两组。微创组47例(67颗患牙),采用微创超薄贴面修复;研究组47例(68颗患牙),采用CAD/CAM全瓷贴面修复。比较两组患者炎症反应、口腔菌群微环境、牙体美观度、修复效果及并发症发生率。结果:治疗后1个月,研究组肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)水平低于微创组(P<0.05);研究组牙卟啉单胞菌、具核梭杆菌、伴放线放线杆菌数量均低于微创组(P<0.05)。治疗后6个月,研究组红色美学指数评分(Pink Esthetic Score,PES)、改良版美国公共卫生服务(United States Public Health Service,USPHS)评分均高于微创组(P<0.05)。研究组并发症发生率低于微创组(P<0.05)。结论:CAD/CAM全瓷贴面修复前牙间隙修复效果和安全性良好,不仅对患者口腔菌群微环境影响较小,有利于减轻修复后炎症反应,还能明显提升牙体美观度。展开更多
This study investigated the impacts of key parameters in CAM6's deep convection and cloud physics schemes on the simulation of summer-mean precipitation over East Asia through conducting perturbed parameter ensemb...This study investigated the impacts of key parameters in CAM6's deep convection and cloud physics schemes on the simulation of summer-mean precipitation over East Asia through conducting perturbed parameter ensemble(PPE)experiments.Utilizing the experimental platform of CAM6,a suite of 128 PPE simulations spanning 19792014 were generated through simultaneously perturbing 12 selected parameters.Using EOF analysis,this study firstly extracted the first two leading modes of the precipitation simulation biases.The authors further pinpointed the most critical parameters that have the most influential effects on the precipitation simulation biases,through conducting generalized linear model analysis.The first leading mode of precipitation simulation biases is primarily influenced by parameters from the cloud physics scheme,including the linear effects of dcs and eii,and the nonlinear effect of rhminl*dcs.These parameters influence the simulated total precipitation(PrecT)mainly by altering the large-scale precipitation(PrecL).The second leading mode is predominantly governed by the convection scheme parameter dmpdz,reflecting a competition between the changes in convective precipitation(PrecC)and PrecL in response to variations in dmpdz.An increase in dmpdz induces decreased PrecC and increased PrecL in East Asia,and both of the changes collectively shape the ultimate PrecT response to the adjusted dmpdz.Lastly,it is noteworthy that the nonlinear effect due to the interaction among parameters warrants attention when concurrently adjusting multiple parameters,and the precipitation biases from the PPE simulations resemble those identified through EOF analysis on the AMIP simulations,implying our findings may provide potential reference for other AGCMs.展开更多
针对金刚石滚轮是一种回转体零件以及其加工制造过程中信息化集成程度低等特点,对金刚石滚轮的特征信息提取、特征加工方案决策、数控程序后置处理等关键技术进行了研究,采用了产品模型数据交换标准STEP AP 242,实现对金刚石滚轮的制造...针对金刚石滚轮是一种回转体零件以及其加工制造过程中信息化集成程度低等特点,对金刚石滚轮的特征信息提取、特征加工方案决策、数控程序后置处理等关键技术进行了研究,采用了产品模型数据交换标准STEP AP 242,实现对金刚石滚轮的制造特征信息提取,使用STEP AP 242和PDM相结合的集成方式,将金刚石滚轮三维模型作为制造加工信息的载体,并选择SolidWorks作为CAD和CAM软件,以及选择Aras Innovator作为PDM平台,使用C#编程语言和数据库技术开发了金刚石滚轮CAD/CAPP/CAM/PDM集成系统,并进行了实例验证。展开更多
文摘目的:观察微创超薄与计算机辅助设计与制造(Computer Aided Design/Computer Aided Manufacturing,CAD/CAM)全瓷贴面修复前牙间隙的美学效果及对口腔菌群微环境的影响。方法:选取笔者医院2023年2月-2025年2月收治的94例(共135颗患牙)前牙间隙患者为研究对象,采用随机数字表法分为两组。微创组47例(67颗患牙),采用微创超薄贴面修复;研究组47例(68颗患牙),采用CAD/CAM全瓷贴面修复。比较两组患者炎症反应、口腔菌群微环境、牙体美观度、修复效果及并发症发生率。结果:治疗后1个月,研究组肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)水平低于微创组(P<0.05);研究组牙卟啉单胞菌、具核梭杆菌、伴放线放线杆菌数量均低于微创组(P<0.05)。治疗后6个月,研究组红色美学指数评分(Pink Esthetic Score,PES)、改良版美国公共卫生服务(United States Public Health Service,USPHS)评分均高于微创组(P<0.05)。研究组并发症发生率低于微创组(P<0.05)。结论:CAD/CAM全瓷贴面修复前牙间隙修复效果和安全性良好,不仅对患者口腔菌群微环境影响较小,有利于减轻修复后炎症反应,还能明显提升牙体美观度。
基金jointly supported by the National Key Research and Development Program of China [grant number 2022YFF0802004]the Excellent Youth Natural Science Foundation of Jiangsu Province [grant number BK20230061]the Joint Open Project of KLME&CIC-FEMD[grant number KLME202501]。
文摘This study investigated the impacts of key parameters in CAM6's deep convection and cloud physics schemes on the simulation of summer-mean precipitation over East Asia through conducting perturbed parameter ensemble(PPE)experiments.Utilizing the experimental platform of CAM6,a suite of 128 PPE simulations spanning 19792014 were generated through simultaneously perturbing 12 selected parameters.Using EOF analysis,this study firstly extracted the first two leading modes of the precipitation simulation biases.The authors further pinpointed the most critical parameters that have the most influential effects on the precipitation simulation biases,through conducting generalized linear model analysis.The first leading mode of precipitation simulation biases is primarily influenced by parameters from the cloud physics scheme,including the linear effects of dcs and eii,and the nonlinear effect of rhminl*dcs.These parameters influence the simulated total precipitation(PrecT)mainly by altering the large-scale precipitation(PrecL).The second leading mode is predominantly governed by the convection scheme parameter dmpdz,reflecting a competition between the changes in convective precipitation(PrecC)and PrecL in response to variations in dmpdz.An increase in dmpdz induces decreased PrecC and increased PrecL in East Asia,and both of the changes collectively shape the ultimate PrecT response to the adjusted dmpdz.Lastly,it is noteworthy that the nonlinear effect due to the interaction among parameters warrants attention when concurrently adjusting multiple parameters,and the precipitation biases from the PPE simulations resemble those identified through EOF analysis on the AMIP simulations,implying our findings may provide potential reference for other AGCMs.
文摘针对金刚石滚轮是一种回转体零件以及其加工制造过程中信息化集成程度低等特点,对金刚石滚轮的特征信息提取、特征加工方案决策、数控程序后置处理等关键技术进行了研究,采用了产品模型数据交换标准STEP AP 242,实现对金刚石滚轮的制造特征信息提取,使用STEP AP 242和PDM相结合的集成方式,将金刚石滚轮三维模型作为制造加工信息的载体,并选择SolidWorks作为CAD和CAM软件,以及选择Aras Innovator作为PDM平台,使用C#编程语言和数据库技术开发了金刚石滚轮CAD/CAPP/CAM/PDM集成系统,并进行了实例验证。
