Objective:To discuss the value of lymph node mapping in rabbit liver cancer with nanocarbon and methylene blue injecta.Methods:Rabbit liver cancer model was established by transplanting VX2 cells with laparotomy in ce...Objective:To discuss the value of lymph node mapping in rabbit liver cancer with nanocarbon and methylene blue injecta.Methods:Rabbit liver cancer model was established by transplanting VX2 cells with laparotomy in celiac planting method.Twenty Japan white rabbits were divided into two groups randomly.Each group had 10 rabbits.Lymph node mapping in (wo groups rabbit liver cancer were observed.Two groups rabbit liver cancer and local lymph nodes were removed.The number and location of local lymph nodes were recorded,and then the samples were obtained from both groups.Results:The lymph nodes dyed time was(100.50±29.92) s in nanocarbon group,and(11.20+4.18) s in methylene blue group with statistical significance between two groups(P=0.000).In the comparison of lymph node fading time,nanocarbon group was(2.22±0.74) h,methylene blue group was(1.63+0.54) h,nanocarbon group was longer than the methylene blue group,but without statistical significance(P=0.058).The accuracy was 87.5% (35/40) in methylene blue group,while,the nanocarbon group was 87.2%(34/39),with statistical significance(P=1.000).Conclusions:Experimental results show that application of nanocarbon injection and methylene blue injection during resection of liver cancer and local lymph nodes in rabbit liver cancer model has obvious tracer function in liver cancer and lymphatic drainage. It can reduce the complexity and risk of the operation,and avoid the blindness in the process of traditional lymph node dissection surgery.Besides,they can effectively reduce the number of residual lymph nodes after operation.It can achieve the lymph node dissection more thoroughly, promptly,easily and safely.展开更多
To study the curative effect of wil sonii injecta on severe head injury (SHI).Methods: A total of 120 patients with SHI were divided randomly into 2 groups, the patients treated with conventional methods as Group A (n...To study the curative effect of wil sonii injecta on severe head injury (SHI).Methods: A total of 120 patients with SHI were divided randomly into 2 groups, the patients treated with conventional methods as Group A (n=60) and the patients treated with wilsonii injecta as Group B (n=60). The changes o f neural function indexes were evaluated with Glasgow Coma Scale (GCS) before tr eatment and with Glasgow Outcome Scale (GOS) after treatment, simultaneously, th e parameters of hemorrheological indexes (HI), brain electrical activity map (BE AM) and transcranial Doppler sonography (TCD) were observed before and after tre atment.Results: In Group B, the clinical GCS, the HI, the BEAM and the prognosis GOS were improved much more than those in Group A. And the TCD parame ters in Group B decreased, which had significant difference compared with that i n Group A (P< 0.01 ).Conclusions: Wilsonii injecta can rapidly improve the injured p ersons’ conscious states, the abnormal BEAM and the surviving quality. It sugges ts that the improvement of the HI is related to the relief of the vasospasm of the arterial blood vessels in the brain, which may be one of the important mecha nisms of wilsonii injecta in improving the prognosis.展开更多
文摘Objective:To discuss the value of lymph node mapping in rabbit liver cancer with nanocarbon and methylene blue injecta.Methods:Rabbit liver cancer model was established by transplanting VX2 cells with laparotomy in celiac planting method.Twenty Japan white rabbits were divided into two groups randomly.Each group had 10 rabbits.Lymph node mapping in (wo groups rabbit liver cancer were observed.Two groups rabbit liver cancer and local lymph nodes were removed.The number and location of local lymph nodes were recorded,and then the samples were obtained from both groups.Results:The lymph nodes dyed time was(100.50±29.92) s in nanocarbon group,and(11.20+4.18) s in methylene blue group with statistical significance between two groups(P=0.000).In the comparison of lymph node fading time,nanocarbon group was(2.22±0.74) h,methylene blue group was(1.63+0.54) h,nanocarbon group was longer than the methylene blue group,but without statistical significance(P=0.058).The accuracy was 87.5% (35/40) in methylene blue group,while,the nanocarbon group was 87.2%(34/39),with statistical significance(P=1.000).Conclusions:Experimental results show that application of nanocarbon injection and methylene blue injection during resection of liver cancer and local lymph nodes in rabbit liver cancer model has obvious tracer function in liver cancer and lymphatic drainage. It can reduce the complexity and risk of the operation,and avoid the blindness in the process of traditional lymph node dissection surgery.Besides,they can effectively reduce the number of residual lymph nodes after operation.It can achieve the lymph node dissection more thoroughly, promptly,easily and safely.
文摘To study the curative effect of wil sonii injecta on severe head injury (SHI).Methods: A total of 120 patients with SHI were divided randomly into 2 groups, the patients treated with conventional methods as Group A (n=60) and the patients treated with wilsonii injecta as Group B (n=60). The changes o f neural function indexes were evaluated with Glasgow Coma Scale (GCS) before tr eatment and with Glasgow Outcome Scale (GOS) after treatment, simultaneously, th e parameters of hemorrheological indexes (HI), brain electrical activity map (BE AM) and transcranial Doppler sonography (TCD) were observed before and after tre atment.Results: In Group B, the clinical GCS, the HI, the BEAM and the prognosis GOS were improved much more than those in Group A. And the TCD parame ters in Group B decreased, which had significant difference compared with that i n Group A (P< 0.01 ).Conclusions: Wilsonii injecta can rapidly improve the injured p ersons’ conscious states, the abnormal BEAM and the surviving quality. It sugges ts that the improvement of the HI is related to the relief of the vasospasm of the arterial blood vessels in the brain, which may be one of the important mecha nisms of wilsonii injecta in improving the prognosis.