1.INTRODUCTION Vitreoretinal lymphoma(VRL)is a rare subtype of central nervous system lymphoma(CNSL)that predominantly comprises B-cell lymphomas.Because of its clinical resemblance to uveitis and transient response t...1.INTRODUCTION Vitreoretinal lymphoma(VRL)is a rare subtype of central nervous system lymphoma(CNSL)that predominantly comprises B-cell lymphomas.Because of its clinical resemblance to uveitis and transient response to glucocorticoid therapy,the diagnosis of VRL is often delayed.1 Although initial manifestations appear indolent,the disease can lead to irreversible vision loss or central nervous system(CNS)relapse,resulting in a poor prognosis.2 Based on the site of initial malignant lymphocyte infiltration,primary VRL(PVRL)originates in the vitreous or retina without CNS or systemic involvement,whereas secondary VRL(SVRL)arises from CNSL or systemic lymphoma.展开更多
基金Funding received from Noncommunicable Chronic Diseases-National Science and Technology Major Project(2025ZD0544300).
文摘1.INTRODUCTION Vitreoretinal lymphoma(VRL)is a rare subtype of central nervous system lymphoma(CNSL)that predominantly comprises B-cell lymphomas.Because of its clinical resemblance to uveitis and transient response to glucocorticoid therapy,the diagnosis of VRL is often delayed.1 Although initial manifestations appear indolent,the disease can lead to irreversible vision loss or central nervous system(CNS)relapse,resulting in a poor prognosis.2 Based on the site of initial malignant lymphocyte infiltration,primary VRL(PVRL)originates in the vitreous or retina without CNS or systemic involvement,whereas secondary VRL(SVRL)arises from CNSL or systemic lymphoma.
