Myocardial infarction results in the loss of a massive amount of cardiomyocytes(CMs),ultimately leading to heart failure(HF).Although current medical therapeutics can alleviate the symptoms of myocardial infarction,th...Myocardial infarction results in the loss of a massive amount of cardiomyocytes(CMs),ultimately leading to heart failure(HF).Although current medical therapeutics can alleviate the symptoms of myocardial infarction,they cannot eliminate the ischemia-induced CM loss(Hume et al.,2023).In adult mammals,the reparatory response to myocardial infarction is the formation of scar tissue,which compromises heart function(Ebrahimi,2018).展开更多
基金financially supported by the National Key R&D Program of China(2023YFA1800600 and 2018YFA0800501)the National Natural Science Foundation of China(32230032 and 82400316)。
文摘Myocardial infarction results in the loss of a massive amount of cardiomyocytes(CMs),ultimately leading to heart failure(HF).Although current medical therapeutics can alleviate the symptoms of myocardial infarction,they cannot eliminate the ischemia-induced CM loss(Hume et al.,2023).In adult mammals,the reparatory response to myocardial infarction is the formation of scar tissue,which compromises heart function(Ebrahimi,2018).
