Objectives To study the as-sociation between infection with chlamydia pneumoniaand acute myocardial infarction (AMI). MethodsSerology of chlamydia pneumoniae specific IgG、IgMantibodies were measured by microimmunoflu...Objectives To study the as-sociation between infection with chlamydia pneumoniaand acute myocardial infarction (AMI). MethodsSerology of chlamydia pneumoniae specific IgG、IgMantibodies were measured by microimmunofluores-cence test in groups of acute myocardial infarction(AMI) and health control(HC). Results The total in-fection positive rates were 30.6% in HC group and88.1% in AMI group, including the previous infectionrates which were 30.6% and 71.4%, while the acuteinfection rates were 0% and 16.7%. The frequency oftotal infection, previous infection and acute infectionwas significantly higher in AMI group than in the HCgroup. Odds Ratio for the development of AMI were16.82, 5.68, 14.2, respectively(95% CI 5.83 to 48.54,2.46 to 13.11, 1.68 to 119.97). Geometric mean IgGtitre was significantly higher in patients with AMIcompared with the HC group (P<0.01). There is noIgM positive in HC group but there were two cases inAMI group. Conclusions The presence of high titersof immmunoglobulin G in AMI. Chlamydia pneumoniainfection may be a risk factor for the AMI.展开更多
文摘Objectives To study the as-sociation between infection with chlamydia pneumoniaand acute myocardial infarction (AMI). MethodsSerology of chlamydia pneumoniae specific IgG、IgMantibodies were measured by microimmunofluores-cence test in groups of acute myocardial infarction(AMI) and health control(HC). Results The total in-fection positive rates were 30.6% in HC group and88.1% in AMI group, including the previous infectionrates which were 30.6% and 71.4%, while the acuteinfection rates were 0% and 16.7%. The frequency oftotal infection, previous infection and acute infectionwas significantly higher in AMI group than in the HCgroup. Odds Ratio for the development of AMI were16.82, 5.68, 14.2, respectively(95% CI 5.83 to 48.54,2.46 to 13.11, 1.68 to 119.97). Geometric mean IgGtitre was significantly higher in patients with AMIcompared with the HC group (P<0.01). There is noIgM positive in HC group but there were two cases inAMI group. Conclusions The presence of high titersof immmunoglobulin G in AMI. Chlamydia pneumoniainfection may be a risk factor for the AMI.
