B iolum inescence in aghg is a khd ofem erghg detection technology at cellular, m olecu lar and genetic level. The most popular b io lum m inescence in aghg model is diffusion approxin ation （DA）. However, because ...B iolum inescence in aghg is a khd ofem erghg detection technology at cellular, m olecu lar and genetic level. The most popular b io lum m inescence in aghg model is diffusion approxin ation （DA）. However, because of the ill-posedness of the D A -based hverse problem and the instability of reconstruction algorithm s, the location accuracy of the reconstucted sources is low. Radiative transfer equation （RTE）, which considers the direction of the photon m igration and the effect of absorption and scattering in tissues, can accurately express the transmission ofbiolum hescent photns through the tissues. In this paper, we studied the biolum hescence inaging based on the RTE. 2D sinuiations were performed, and quantitative evaluation was given by the absolute source position error, the relative source area error and the m h in um bound hg box. The resu Its of the experin ent showed that the in aging quality based on R TE was beer than thatone based on D A.展开更多
The photonic characteristics of chromophore-containing metal-organic frameworks(MOFs)have led to extensive photophysical studies in an effort to capitalize on the potency of precisely controlled chromophore ensembles....The photonic characteristics of chromophore-containing metal-organic frameworks(MOFs)have led to extensive photophysical studies in an effort to capitalize on the potency of precisely controlled chromophore ensembles.Several examples have laid the foundation that demonstrates how photophysical properties of chromophores can be manipulated by tuning their communications(interactions)through integration within a MOF matrix.The main focus of this review is on harnessing the versatile MOF platform to accentuate the photophysical properties of integrated chromophores.In particular,this review will highlight chromophore dynamics that enhance,alter,or tune the photoluminescence response of single-and multi-chromophore-containing scaffolds,as well as alignment-guided anisotropic fluorescence.Building upon this groundwork,utilization of a hybrid crystalline motif can induce preferential orientation of chromophores resulting in enhanced communication and tailored behavior compared to randomly oriented emissive molecules.Moreover,frameworks that produce upconverted emission via sensitized triplet-triplet annihilation(sTTA),excited-state absorption(ESA),energy transfer upconversion(ETU),multi-photon absorption(MPA),or second-harmonic generation(SHG)can invoke dynamic control of material properties using photochromic linkers and will be discussed herein with a focus on the effects of chromophore alignment.Integration within a framework is a vehicle tofuse chromophores into solid-state platforms,opening an avenue for chromophore utilization in applications such as portable electronics that require solids or thin films.For those reasons,the design of chromophore-containing MOFs with desirable properties that rely on the alignment and communication of hundreds of chromophores within a single platform is a pressing demand for the development of futuristic technologies.展开更多
基金The Funding of Jiangsu Innovation Program for Graduate Educationgrant number:SJLX15_0115+1 种基金the Fundamental Research Funds for the Central Universities of Chinagrant number NZ2014101
文摘B iolum inescence in aghg is a khd ofem erghg detection technology at cellular, m olecu lar and genetic level. The most popular b io lum m inescence in aghg model is diffusion approxin ation （DA）. However, because of the ill-posedness of the D A -based hverse problem and the instability of reconstruction algorithm s, the location accuracy of the reconstucted sources is low. Radiative transfer equation （RTE）, which considers the direction of the photon m igration and the effect of absorption and scattering in tissues, can accurately express the transmission ofbiolum hescent photns through the tissues. In this paper, we studied the biolum hescence inaging based on the RTE. 2D sinuiations were performed, and quantitative evaluation was given by the absolute source position error, the relative source area error and the m h in um bound hg box. The resu Its of the experin ent showed that the in aging quality based on R TE was beer than thatone based on D A.
基金the NSF CAREER Award(DM R-1553634)a Cottrell Scholar Award from the Research Corporation for Science Advancement.N.B.S.also acknowledges support from the Sloan Research Fellowship provided by the Alfred P.Sloan Foundation and the Dreyfus Teaching-Scholar Award supported by the Dreyflis Foundation.
文摘The photonic characteristics of chromophore-containing metal-organic frameworks(MOFs)have led to extensive photophysical studies in an effort to capitalize on the potency of precisely controlled chromophore ensembles.Several examples have laid the foundation that demonstrates how photophysical properties of chromophores can be manipulated by tuning their communications(interactions)through integration within a MOF matrix.The main focus of this review is on harnessing the versatile MOF platform to accentuate the photophysical properties of integrated chromophores.In particular,this review will highlight chromophore dynamics that enhance,alter,or tune the photoluminescence response of single-and multi-chromophore-containing scaffolds,as well as alignment-guided anisotropic fluorescence.Building upon this groundwork,utilization of a hybrid crystalline motif can induce preferential orientation of chromophores resulting in enhanced communication and tailored behavior compared to randomly oriented emissive molecules.Moreover,frameworks that produce upconverted emission via sensitized triplet-triplet annihilation(sTTA),excited-state absorption(ESA),energy transfer upconversion(ETU),multi-photon absorption(MPA),or second-harmonic generation(SHG)can invoke dynamic control of material properties using photochromic linkers and will be discussed herein with a focus on the effects of chromophore alignment.Integration within a framework is a vehicle tofuse chromophores into solid-state platforms,opening an avenue for chromophore utilization in applications such as portable electronics that require solids or thin films.For those reasons,the design of chromophore-containing MOFs with desirable properties that rely on the alignment and communication of hundreds of chromophores within a single platform is a pressing demand for the development of futuristic technologies.
