Although E Maddy （1997） says on naturalism： ＂This is not, in itself, a philosophy of mathematics [...]＂ （161）, already by its name, or by those whose interest has called on it （Quine, Putnam et al.） ... it an...Although E Maddy （1997） says on naturalism： ＂This is not, in itself, a philosophy of mathematics [...]＂ （161）, already by its name, or by those whose interest has called on it （Quine, Putnam et al.） ... it anyhow reveals desire to be it. Insofar as otherwise, the semantic potential of the word leaves far behind it （after all scarce） results it achieved from the relation of an exact （mathematical） expression and （overly rich） intuitive reality of Being. We plead here already from the perspective of the slogan ＂One and All＂ of the first philosopher： Tales, when by the number （which one forebodes） one could go to such an extent into areas of reality （Pythagoras）, or when （especially in the human sphere） is being over again actual final cause of Aristotle the philosophy and the mathematics to accomplish far more fruitful encounter with the Being. Alain Badiou （1988） has already pointed that： ＂Mathematics is ontology,＂ and the category theory in mathematics, having covered by itself other fields of this science, continues to find applications in a series of＂non-traditional＂ domains of reality. In that correlation the philosophy can express its （primary） needs for truth, justice, beauty, ... as well as for the overall development in the sense of purpose--also because of an undreamed power of the technological development （of hardwares and softwares） today. Namely, the naturalism in mathematics, which developed an abundant reflection on the place （importance of） the mathematical idiom in sciences--in the balance of criticism--has come rather to meager provisions, such as： ＂preestablished harmony of thinking,＂ ＂ontic commitment,＂ （Quine 1960） ＂the hygiene of mind,＂ （Maddy 1996） ＂success argument,＂ （Putnam 1975） ＂pragmatic argument,＂ （Resnik 1981） etc., which only are few places from the encounter of an exact expression such as is mathematical one and the reality of natuural sciences. Instead of philosophy of mathematics to radicalize its claims from the perspective of that （powerful） mathematical idiom and the excessive reality of Being and man＇s place in it--this time, in the spirit of biocosmology （neo-Aristotelism）.展开更多
1.文学常识free verse(自由体诗)-It is poetry that has anirregular rhythm and line length and that attemptsto avoid any predetermined verse structure;instead.it uses the cadences(声音的抑扬顿挫)of
This paper presents the results of an experimental deprivation study conducted with 64 participants. All participants had to do without mobile phone, internet and TV for 15 days each. The main research objective was t...This paper presents the results of an experimental deprivation study conducted with 64 participants. All participants had to do without mobile phone, internet and TV for 15 days each. The main research objective was to examine the differences of indispensability levels and experiences during these non-usage phases. Mobile phones turned out to be most indispensable followed by Internet. Involvement of the medium into daily routine is an important part of short-term indispensability and will be dealt with in detail in this paper.展开更多
Dear Editor,Aerobic exercise is well known to improve cognitive functions including hippocampus-dependent spatial memory[1]and object recognition[2].Regarding the molecular mechanisms,the indispensable role of brain-d...Dear Editor,Aerobic exercise is well known to improve cognitive functions including hippocampus-dependent spatial memory[1]and object recognition[2].Regarding the molecular mechanisms,the indispensable role of brain-derived neurotrophic factor(BDNF)in governing exercise-induced neural plasticity has been demonstrated for the improvement of learning and memory[3].Our recent study further demonstrated the activation of mechanistic target of rapamycin pathways downstream of BDNF to drive synaptic protein synthesis upon persistent exercise[4],but leaving the effect of exercise on the post-translational modification of proteins largely unknown.展开更多
SOX9(SRY-related HMG box gene 9)is an essential regulator of male sex determination and testis differentiation in many vertebrate species.However,the functional role of Sox9 in testis differentiation has not yet been ...SOX9(SRY-related HMG box gene 9)is an essential regulator of male sex determination and testis differentiation in many vertebrate species.However,the functional role of Sox9 in testis differentiation has not yet been identified in any reptilian species.Herein,Sox9 knockdown in the red-eared slider turtle(Trachemys scripta)embryos at a male-producing temperature led to complete male-to-female sex reversal,characterized by the formation of an ovary-like structure,disappearance of male marker AMH,and ectopic expression of ovarian regulator FOXL2,as well as a female distribution pattern of germ cells.Conversely,in-ovo overexpression of Sox9 at a female-producing temperature resulted in partial masculinization of putative female embryos,with the coexistence of AMH and FOXL2.Our study provides the first direct evidence that Sox9 is indispensable for testicular differentiation in a reptilian species,further confirming the conserved role of Sox9 in vertebrate sexual development.展开更多
Pipeline plays an indispensable role in process industries,because the progressing crack-like defects of in it may result in serious accidents and significant economic losses.Therefore,it is essential to detect the cr...Pipeline plays an indispensable role in process industries,because the progressing crack-like defects of in it may result in serious accidents and significant economic losses.Therefore,it is essential to detect the cracks occurred in pipelines.The axial crack-like defects in elbows with different angle are inspected by using the T(0,1)mode guided waves,in which different configurations including 45°,90°,135°and 180°(straight pipe)are considered respectively.Firstly,the detection sensitivity for different defect location is experimentally investigated.After that,finite element simulation is used to explore the propagation behaviors of T(0,1)mode in different bend structures.Simulation and experiment results show that the crack in different areas of the elbow can affect the detection sensitivity.It can be found that the detection sensitivity of crack in the middle area of the elbow is higher compared to the extrados and intrados of the elbow.Finally,the mode conversion is also investigated when the T(0,1)crosses the bend,and the results show that bend is a key factor to the mode conversion phenomenon which presents between the T(0,1)mode and F(1,2)mode.展开更多
Electro-auriculoacupuncture anesthe-sia was used in 57 instances of cystoscopy incomparison witn 22 similar cases with sur-face anesthesia. The results are reported asfollows:
In recent years,high fidelity numerical models simultaneously reflecting the behaviors of mechanical systems and their underlying materials have gradually become an indispensable part of modern mechanical and producti...In recent years,high fidelity numerical models simultaneously reflecting the behaviors of mechanical systems and their underlying materials have gradually become an indispensable part of modern mechanical and production engineering.In different contexts,the attempt to bridge me chanical engineering with materials science and to replace phenomenological models by the physical ones are named either as integrated computational materials engineering(ICME)or integrated structures and materi als design(ISMD).展开更多
0 INTRODUCTION China's dependence on foreign crude oil exceeds 70%,posing significant challenges to national energy security.However,traditional,easily discoverable conventional oil exploration targets are increas...0 INTRODUCTION China's dependence on foreign crude oil exceeds 70%,posing significant challenges to national energy security.However,traditional,easily discoverable conventional oil exploration targets are increasingly scarce.As an important strategic replacement resource,shale oil plays an indispensable role in safeguarding national energy security and has gradually become a hotspot in the oil and gas exploration sector.展开更多
The Nucleic Acid Laboratory,a division of the Clinical Laboratory Department,is responsible for performing real-time PCR(qPCR)assays to rapidly detect infectious diseases,genetic disorders,and more[1].As the gold stan...The Nucleic Acid Laboratory,a division of the Clinical Laboratory Department,is responsible for performing real-time PCR(qPCR)assays to rapidly detect infectious diseases,genetic disorders,and more[1].As the gold standard,qPCR has played an indispensable role in diagnosing pandemic infections,such as the coronavirus disease 2019(COVID-19)[2].展开更多
Alzheimer's disease(AD) is the most common age-related dementia without cures. Between 2000 and 2017, deaths resulting from AD increased 145%. Based on the latest statistical data, more than 50 million people in t...Alzheimer's disease(AD) is the most common age-related dementia without cures. Between 2000 and 2017, deaths resulting from AD increased 145%. Based on the latest statistical data, more than 50 million people in the world suffered this devastating disease, which is one of major burdens in modern public health system(Alzheimer's Association, 2020).展开更多
The Italian care situation with regards to prostheses and aids is satisfying. The norm which establishes the ways in which aids can be supplied to disabled people goes back to 1999 and,even though it is based on corre...The Italian care situation with regards to prostheses and aids is satisfying. The norm which establishes the ways in which aids can be supplied to disabled people goes back to 1999 and,even though it is based on correct principles and even though it has produced positive effects in the improvement of the life of disabled people,it must be updated in the light of the more recent technological and scientific innovations and of the new information instruments such as the diffusion of information and communication systems.展开更多
The effect of popping and fermentation on protein quality of three different varieties of amaranth grains cultivated in Ethiopia was evaluated. Total lysine content of the grains was higher than that of commonly avail...The effect of popping and fermentation on protein quality of three different varieties of amaranth grains cultivated in Ethiopia was evaluated. Total lysine content of the grains was higher than that of commonly available cereals but close to that of legumes. Methionine and cysteine contents in the grains were also higher than that found in cereal and legume proteins. Percentage of total indispensable amino acids, excluding tryptophan, was 43% - 49%, which was higher than WHO reference pattern (31%). Popping resulted in 36% and 37% reduction in total lysine and cysteine contents, respectively, whereas fermentation reduced cysteine, lysine and methionine contents by 16%, 20% and 20%, respectively. From the free amino acids, histidine was the major indispensable amino acid but threonine was not detected. During popping, all free amino acids, except threonine, were reduced. On the other hand, fermentation significantly increased (p < 0.01) most amino acids except arginine, which was significantly decreased (p < 0.01), and tyrosine and glutamic acid, for which no change was observed. Popping decreased in vitro protein digestibility (IVPD) by 8.3% - 17.1% while fermentation increased IVPD by 4.8% - 7.5%. Substitution of amaranth for wheat and/or maize during complementary food formulation could contribute much to the daily requirements of indispensable amino acids of young children.展开更多
Water is indispensable to life having a direct influence on man’s health. Since environmental pollution is getting worse with each passing day, drinking water is also becoming seriously polluted which threatens healt...Water is indispensable to life having a direct influence on man’s health. Since environmental pollution is getting worse with each passing day, drinking water is also becoming seriously polluted which threatens health and safety, Many people have contracted cancers and other serious diseases as a result of drinking such water for a long time. The Jinning Brand water purifier serial product designed and developed展开更多
The Negative list is an indispensable part of free trade zone constructions.The success of Shanghai’s Free Trade Experiment zone has a remarkable feature that the deep promotion of pre-establishment national treatmen...The Negative list is an indispensable part of free trade zone constructions.The success of Shanghai’s Free Trade Experiment zone has a remarkable feature that the deep promotion of pre-establishment national treatment and negative list system.Popular trend Since the first edition of the"negative list"came out in the Shanghai Free Trade Zone in 2013,it has become a popular trend in展开更多
Water is indispensable to life having a direct influence on man’s health. Since environmental pollution is getting worse with each passing day, drinking water is also becoming seriously polluted which threatens healt...Water is indispensable to life having a direct influence on man’s health. Since environmental pollution is getting worse with each passing day, drinking water is also becoming seriously polluted which threatens health and safety. Many people have contracted cancers展开更多
文摘Although E Maddy （1997） says on naturalism： ＂This is not, in itself, a philosophy of mathematics [...]＂ （161）, already by its name, or by those whose interest has called on it （Quine, Putnam et al.） ... it anyhow reveals desire to be it. Insofar as otherwise, the semantic potential of the word leaves far behind it （after all scarce） results it achieved from the relation of an exact （mathematical） expression and （overly rich） intuitive reality of Being. We plead here already from the perspective of the slogan ＂One and All＂ of the first philosopher： Tales, when by the number （which one forebodes） one could go to such an extent into areas of reality （Pythagoras）, or when （especially in the human sphere） is being over again actual final cause of Aristotle the philosophy and the mathematics to accomplish far more fruitful encounter with the Being. Alain Badiou （1988） has already pointed that： ＂Mathematics is ontology,＂ and the category theory in mathematics, having covered by itself other fields of this science, continues to find applications in a series of＂non-traditional＂ domains of reality. In that correlation the philosophy can express its （primary） needs for truth, justice, beauty, ... as well as for the overall development in the sense of purpose--also because of an undreamed power of the technological development （of hardwares and softwares） today. Namely, the naturalism in mathematics, which developed an abundant reflection on the place （importance of） the mathematical idiom in sciences--in the balance of criticism--has come rather to meager provisions, such as： ＂preestablished harmony of thinking,＂ ＂ontic commitment,＂ （Quine 1960） ＂the hygiene of mind,＂ （Maddy 1996） ＂success argument,＂ （Putnam 1975） ＂pragmatic argument,＂ （Resnik 1981） etc., which only are few places from the encounter of an exact expression such as is mathematical one and the reality of natuural sciences. Instead of philosophy of mathematics to radicalize its claims from the perspective of that （powerful） mathematical idiom and the excessive reality of Being and man＇s place in it--this time, in the spirit of biocosmology （neo-Aristotelism）.
文摘1.文学常识free verse(自由体诗)-It is poetry that has anirregular rhythm and line length and that attemptsto avoid any predetermined verse structure;instead.it uses the cadences(声音的抑扬顿挫)of
文摘This paper presents the results of an experimental deprivation study conducted with 64 participants. All participants had to do without mobile phone, internet and TV for 15 days each. The main research objective was to examine the differences of indispensability levels and experiences during these non-usage phases. Mobile phones turned out to be most indispensable followed by Internet. Involvement of the medium into daily routine is an important part of short-term indispensability and will be dealt with in detail in this paper.
基金by the National Key Research and Development Program of China(2016YFC1306702 and 2020YFA0113600)the National Natural Science Foundation of China(81771455,81971067,and 32070955)+3 种基金the Science and Technology Program of Guangdong Province,China(2018B030334001)the Outstanding Scholar Program of Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory)(2018GZR110102002)the Science and Technology Program of Guangzhou,China(202007030012)the Natural Science Foundation of Guangdong Province,China(2019A1515011772).
文摘Dear Editor,Aerobic exercise is well known to improve cognitive functions including hippocampus-dependent spatial memory[1]and object recognition[2].Regarding the molecular mechanisms,the indispensable role of brain-derived neurotrophic factor(BDNF)in governing exercise-induced neural plasticity has been demonstrated for the improvement of learning and memory[3].Our recent study further demonstrated the activation of mechanistic target of rapamycin pathways downstream of BDNF to drive synaptic protein synthesis upon persistent exercise[4],but leaving the effect of exercise on the post-translational modification of proteins largely unknown.
基金This study was supported by the National Key Research and Development Program(2018YFD0900203)National Natural Science Foundation of China(31922084,31872960)+1 种基金Natural Science Foundation of Zhejiang Province for Distinguished Young Scholars(LR19C190001)Key Agricultural Project of Ningbo(2019C10018)。
文摘SOX9(SRY-related HMG box gene 9)is an essential regulator of male sex determination and testis differentiation in many vertebrate species.However,the functional role of Sox9 in testis differentiation has not yet been identified in any reptilian species.Herein,Sox9 knockdown in the red-eared slider turtle(Trachemys scripta)embryos at a male-producing temperature led to complete male-to-female sex reversal,characterized by the formation of an ovary-like structure,disappearance of male marker AMH,and ectopic expression of ovarian regulator FOXL2,as well as a female distribution pattern of germ cells.Conversely,in-ovo overexpression of Sox9 at a female-producing temperature resulted in partial masculinization of putative female embryos,with the coexistence of AMH and FOXL2.Our study provides the first direct evidence that Sox9 is indispensable for testicular differentiation in a reptilian species,further confirming the conserved role of Sox9 in vertebrate sexual development.
基金supported by the National Natural Science Foundation of China(Nos.51575185,51175178)
文摘Pipeline plays an indispensable role in process industries,because the progressing crack-like defects of in it may result in serious accidents and significant economic losses.Therefore,it is essential to detect the cracks occurred in pipelines.The axial crack-like defects in elbows with different angle are inspected by using the T(0,1)mode guided waves,in which different configurations including 45°,90°,135°and 180°(straight pipe)are considered respectively.Firstly,the detection sensitivity for different defect location is experimentally investigated.After that,finite element simulation is used to explore the propagation behaviors of T(0,1)mode in different bend structures.Simulation and experiment results show that the crack in different areas of the elbow can affect the detection sensitivity.It can be found that the detection sensitivity of crack in the middle area of the elbow is higher compared to the extrados and intrados of the elbow.Finally,the mode conversion is also investigated when the T(0,1)crosses the bend,and the results show that bend is a key factor to the mode conversion phenomenon which presents between the T(0,1)mode and F(1,2)mode.
文摘Electro-auriculoacupuncture anesthe-sia was used in 57 instances of cystoscopy incomparison witn 22 similar cases with sur-face anesthesia. The results are reported asfollows:
文摘In recent years,high fidelity numerical models simultaneously reflecting the behaviors of mechanical systems and their underlying materials have gradually become an indispensable part of modern mechanical and production engineering.In different contexts,the attempt to bridge me chanical engineering with materials science and to replace phenomenological models by the physical ones are named either as integrated computational materials engineering(ICME)or integrated structures and materi als design(ISMD).
基金supported by the National Natural Science Foundation of China(No.42122017)the Independent innovation research program of China University of Petroleum(East China)(No.21CX06001A)。
文摘0 INTRODUCTION China's dependence on foreign crude oil exceeds 70%,posing significant challenges to national energy security.However,traditional,easily discoverable conventional oil exploration targets are increasingly scarce.As an important strategic replacement resource,shale oil plays an indispensable role in safeguarding national energy security and has gradually become a hotspot in the oil and gas exploration sector.
基金supported by the Basic research and achievement transformation project of Jiulongpo District Science and Technology Bureau[No.2022-02-013-Y].
文摘The Nucleic Acid Laboratory,a division of the Clinical Laboratory Department,is responsible for performing real-time PCR(qPCR)assays to rapidly detect infectious diseases,genetic disorders,and more[1].As the gold standard,qPCR has played an indispensable role in diagnosing pandemic infections,such as the coronavirus disease 2019(COVID-19)[2].
文摘Alzheimer's disease(AD) is the most common age-related dementia without cures. Between 2000 and 2017, deaths resulting from AD increased 145%. Based on the latest statistical data, more than 50 million people in the world suffered this devastating disease, which is one of major burdens in modern public health system(Alzheimer's Association, 2020).
文摘The Italian care situation with regards to prostheses and aids is satisfying. The norm which establishes the ways in which aids can be supplied to disabled people goes back to 1999 and,even though it is based on correct principles and even though it has produced positive effects in the improvement of the life of disabled people,it must be updated in the light of the more recent technological and scientific innovations and of the new information instruments such as the diffusion of information and communication systems.
文摘The effect of popping and fermentation on protein quality of three different varieties of amaranth grains cultivated in Ethiopia was evaluated. Total lysine content of the grains was higher than that of commonly available cereals but close to that of legumes. Methionine and cysteine contents in the grains were also higher than that found in cereal and legume proteins. Percentage of total indispensable amino acids, excluding tryptophan, was 43% - 49%, which was higher than WHO reference pattern (31%). Popping resulted in 36% and 37% reduction in total lysine and cysteine contents, respectively, whereas fermentation reduced cysteine, lysine and methionine contents by 16%, 20% and 20%, respectively. From the free amino acids, histidine was the major indispensable amino acid but threonine was not detected. During popping, all free amino acids, except threonine, were reduced. On the other hand, fermentation significantly increased (p < 0.01) most amino acids except arginine, which was significantly decreased (p < 0.01), and tyrosine and glutamic acid, for which no change was observed. Popping decreased in vitro protein digestibility (IVPD) by 8.3% - 17.1% while fermentation increased IVPD by 4.8% - 7.5%. Substitution of amaranth for wheat and/or maize during complementary food formulation could contribute much to the daily requirements of indispensable amino acids of young children.
文摘Water is indispensable to life having a direct influence on man’s health. Since environmental pollution is getting worse with each passing day, drinking water is also becoming seriously polluted which threatens health and safety, Many people have contracted cancers and other serious diseases as a result of drinking such water for a long time. The Jinning Brand water purifier serial product designed and developed
文摘The Negative list is an indispensable part of free trade zone constructions.The success of Shanghai’s Free Trade Experiment zone has a remarkable feature that the deep promotion of pre-establishment national treatment and negative list system.Popular trend Since the first edition of the"negative list"came out in the Shanghai Free Trade Zone in 2013,it has become a popular trend in
文摘Water is indispensable to life having a direct influence on man’s health. Since environmental pollution is getting worse with each passing day, drinking water is also becoming seriously polluted which threatens health and safety. Many people have contracted cancers
