Active Flux is a third order accurate numerical method which evolves cell averages and point values at cell interfaces independently.It naturally uses a continuous reconstruction,but is stable when applied to hyperbol...Active Flux is a third order accurate numerical method which evolves cell averages and point values at cell interfaces independently.It naturally uses a continuous reconstruction,but is stable when applied to hyperbolic problems.In this work,the Active Flux method is extended for the first time to a nonlinear hyperbolic system of balance laws,namely,to the shallow water equations with bottom topography.We demonstrate how to achieve an Active Flux method that is well-balanced,positivity preserving,and allows for dry states in one spatial dimension.Because of the continuous reconstruction all these properties are achieved using new approaches.To maintain third order accuracy,we also propose a novel high-order approximate evolution operator for the update of the point values.A variety of test problems demonstrates the good performance of the method even in presence of shocks.展开更多
BACKGROUND Dry eye disease(DED)represents a multifactorial condition characterized by ocular discomfort and visual disturbances.The management of DED relies heavily on accurate diagnosis to tailor effective treatments...BACKGROUND Dry eye disease(DED)represents a multifactorial condition characterized by ocular discomfort and visual disturbances.The management of DED relies heavily on accurate diagnosis to tailor effective treatments.Diagnostic approaches encompass both subjective and objective assessments.AIM To review the diagnostic methods used in the process of dry eye disease management.METHODS A comprehensive review of diagnostic approaches for dry eye was performed using scientific databases.Studies published within the last four years were considered.Studies were excluded if a full text was absent or the article was not written in English.Articles were assessed for relevancy,and a total of 107 studies were selected.The selection method used a systematic methodology,which guaranteed an exhaustive assessment of the diagnostic techniques reported in current literature.The study adheres to principles for systematic reviews ensuring dependability and accuracy.The studies were assessed for emphasize on both novel traditional and diagnostic methods for dry eye disease management.RESULTS Key objective tests include tear break-up time,which evaluates tear film stability;fluorescein and lissamine green staining,which assess ocular surface damage and inflammation;tear osmolarity measurement,indicative of tear film quality;and tear volume assessment via Schirmer's test,which evaluates tear production.Advanced imaging techniques such as optical coherence tomography and meibography offer detailed anatomical insights into the ocular surface and meibomian glands,aiding in the diagnosis of underlying structural abnormalities.Moreover,emerging technologies such as matrix metalloproteinase-9 testing and inflammatory biomarkers provide additional diagnostic precision,particularly in identifying inflammatory components of DED.CONCLUSION Integrating a combination of subjective and objective diagnostic tools allows clinicians to comprehensively assess the condition,tailor treatment plans,and monitor therapeutic efficacy.Continued advancements in diagnostic technologies promise to enhance our understanding and management of this prevalent ocular condition.展开更多
Black wolfberry(Lycium ruthenicum)is enriched in phytochemical metabolites which can benefit human health.However,few studies have examined the effects of different fruit drying methods on its polyphenol content,antio...Black wolfberry(Lycium ruthenicum)is enriched in phytochemical metabolites which can benefit human health.However,few studies have examined the effects of different fruit drying methods on its polyphenol content,antioxidant activity,and anti-inflammatory activity.In addition,whether and how consuming dried black wolfberry affects gut microbiota has not been reported.This study assessed the phytochemical profile and bioactivities of black wolfberry dried through different methods,and subsequently characterized changes in human fecal microbiota associated with freeze-dried black wolfberry in vitro.The results showed that freeze-dried samples retained higher total phenolics((49.68±1.62)mg GAE/g DM),tannins((38.64±1.35)mg GAE/g DM),and proanthocyanidins((3.35±0.30)mg/g DM)compared to sun drying or hot air drying(P<0.05),and exhibited higher antioxidant and anti-inflammatory activities.In human fecal inoculum bioreactor fermentations,freeze-dried black wolfberry was associated with increased species richness andα-diversity.At the genus level,fermentations treated with black wolfberry had a higher abundance of lactic acid bacteria including Lactococcus,Bifidobacterium,Lactobacillus,Pediococcus,and Weissella,as well as butyrate-producing bacteria compared to the untreated samples,suggesting enrichment for taxa associated with a healthy gut microbiome.In addition,the black wolfberry treatment group had higher levels of short-chain fatty acids,which were consistent with PICRUSt2 inference.This study defines an optimal method for black wolfberry preservation to retain the beneficial compounds,and provides a foundation for further exploration of its potential benefits for human gut microbiota.展开更多
Suillus granulatus is a valuable wild edible mushroom with a strong umami taste.Different grades of S.granulatus were dried by different methods,including natural air drying(ND),hot air drying(HAD),vacuum drying(VD),a...Suillus granulatus is a valuable wild edible mushroom with a strong umami taste.Different grades of S.granulatus were dried by different methods,including natural air drying(ND),hot air drying(HAD),vacuum drying(VD),and freeze drying(FD).Results showed that VD samples of all grades had the highest equivalent umami concentration(EUC)value(P<0.05).The second grade of ND samples showed the highest EUC value(P<0.05).The first grade of HAD samples showed the highest EUC value(P<0.05).The third grade of FD samples showed the highest EUC value(P<0.05).The third grade of VD samples had a higher EUC value than the other grades of samples dried by VD.Electronic tongue results indicated no significant differences between samples of all grades dried by all methods.Thus,umami taste components are affected by drying method and grade.VD is an appropriate drying method for all sample grades.ND,HAD,and FD are suitable for second-,first-,and third-grade samples,respectively.展开更多
[Objectives] This study was conducted to investigate the drying methods,functional and structure properties of dietary fiber( DF) from peanut shells.[Methods]Peanut shells were used as a raw material to prepare peanut...[Objectives] This study was conducted to investigate the drying methods,functional and structure properties of dietary fiber( DF) from peanut shells.[Methods]Peanut shells were used as a raw material to prepare peanut shell dietary fiber( DF) by hot air drying( HA) and vacuum freeze drying( VF),respectively,and their functional and structural characteristics were compared in detail. [Results]The solubility,water holding capacity,oil holding capacity and swelling capacity of HA-DF and VF-DF were 2. 15 %,7. 63 g/g,7. 73 g/g,10. 35 ml/g and 3. 85 %,14. 98 g/g,15. 25 g/g,15. 85 ml/g,respectively. The total phenol contents were 2. 623 and 5. 173 mg GAE/g,respectively. The IC(50) values of ·OH,O2^-· and DPPH free radicals were 4. 16 and 4. 09 mg/ml,7. 90 and 3. 32 mg/ml,and 3. 19 and 3. 09 mg/ml,respectively. The molecular weight of VF-DF was smaller,and it had narrow molecular weight distribution and denser particles. Electron microscopy showed that VF-DF had a porous network like honeycomb and swelled structure. [Conclusions]This study can provide a theoretical basis for the functional modification and comprehensive utilization of peanut shell dietary fiber.展开更多
Japanese pine, Korean pine and larch are three major softwood species in Korea. Their colors are relatively light, thus easily discolored due to drying and UV irradiation. In this study, they were dried with five diff...Japanese pine, Korean pine and larch are three major softwood species in Korea. Their colors are relatively light, thus easily discolored due to drying and UV irradiation. In this study, they were dried with five different drying methods, steam treated and exposed to weathering. Their colors were measured using a spectrophotometer and comparisons made both among species and drying methods. For Japanese and Korean pines, high temperature dried and steam-dried specimens showed distinct color differences compared with the controls. Steam treatment discolored the dried specimens of Japanese and Korean pines but did not discolor those of larch. After weathering for 144 days the specimens of Japanese pine showed slight color differences among drying methods.展开更多
The porous spherical LiFePO4/C powders were prepared by spray drying and carbothermal method （SDCTM）. Cheaper trivalent iron ion was used as the precursor. The pure olivine phase can be prepared with the spray dryin...The porous spherical LiFePO4/C powders were prepared by spray drying and carbothermal method （SDCTM）. Cheaper trivalent iron ion was used as the precursor. The pure olivine phase can be prepared with the spray drying and subsequent heat-treatment. The average particle size is around 10μm, and the value of porosity is 63.04%. The results indicate that the initial discharge capacity decreases with increasing charge/ discharge rate and reduces from 138.8 mAh · g^-1 at C/20 rate to 98.3 mAh ·g^-1 at 2C rate, while the polarization between the charge and discharge plateaux is enlarged from 53 mv to 347 mv. However, the average discharge efficiency is up to 99.5% at 2C rate compared to 80.6% at C/20 rate from the second cycle.展开更多
A particular porosity method named ＂slot method＂ is implemented in a depth-integrated shallow water flow model （DIVAST） to simulate wetting and drying processes. Discussed is the relationship between the shape fac...A particular porosity method named ＂slot method＂ is implemented in a depth-integrated shallow water flow model （DIVAST） to simulate wetting and drying processes. Discussed is the relationship between the shape factors of the ＂slot＂ and the preset depth used in ＂wetting-drying＂ algorithm. Two typical tests are conducted to examine the performance of the method with the effect of the shape factors of the ＂slot＂ being checked in detail in the first test. Numerical results demonstrate that： 1 ） no additional effort to improve the finite difference scheme is needed to implement ＂slot method＂ in DIVAST, and 2） ＂slot method＂ will simulate wetting and diying processes correctly if the shape factors of the ＂slot＂ being selected properly.展开更多
Background：This experiment was conducted to determine the nutritive value of corn from the north of China for growing pigs.The experiment examined corn variety（LS1,LS2,LS3 and LS4）grown in one location,drying metho...Background：This experiment was conducted to determine the nutritive value of corn from the north of China for growing pigs.The experiment examined corn variety（LS1,LS2,LS3 and LS4）grown in one location,drying method（sun dried and artificially dried）and different drying temperatures.Corn harvested at 20-25%moisture was dried to about 12%moisture by sun drying and artificially drying at 80,100,or 120℃ in a fluidized bed dryer.Ninety-six barrows（average BW of 33.4 ± 2.7 kg）were housed in individual metabolism crates to facilitate separate collection of feces and urine.A five-day collection period followed a seven-day diet acclimation period.Results：The results indicated that variety significantly influenced（P〈0.01）the 1,000 kernel weight of corn but not the bulk weight.Variety also influenced the available energy content（digestible energy of dry matter,P〈0.01;metabolisable energy of dry matter,P〈0.01）and digestibility of organic matter（P〈0.01）,as well as dry matter（P〈0.01）and gross energy（GE）content（P〈0.02）.The drying method of corn significantly influenced the 1,000 kernel weight（P〈0.01）,bulk weight（P〈0.01）and digestibility of ether extract（EE）（P〈0.01）.No effect of drying temperature on the digestibility of organic matter,dry matter（DM）,crude protein（CP）,neutral detergent fiber（NDF）,acid detergent fiber（ADF）and gross energy was observed,but gelatinization（P〈0.05）and test weight（P〈0.01）decreased with an increase in temperature.Conclusions：Variety has a significant impact on the nutritive value of corn for growing pigs,and greater attention needs to be paid to these influences in the assignment of the nutritive value of corn given to growing pigs.展开更多
Ammonium aluminum carbonate hydroxide (AACH) precursor was synthesized by the precipitation reaction of aluminum sulfate and ammonium carbonate. Then the precursor was dealt with five drying methods including ordinary...Ammonium aluminum carbonate hydroxide (AACH) precursor was synthesized by the precipitation reaction of aluminum sulfate and ammonium carbonate. Then the precursor was dealt with five drying methods including ordinary drying, alcohol exchange, vacuum freeze-drying, glycol distillation, n-butanol azeotropic distillation respectively and calcined at 1 200 ℃ for 2 h to get α-Al2O3. The effects of drying methods on preparation of nanometer α-Al2O3 were discussed, and the optimal drying method was confirmed. The structural properties of powders were characterized by XRD, SEM and BET measurements. The results show that vacuum freeze-drying, glycol distillation and n-butanol azeotropic distillation can prevent the powders from aggregating, and among them the n-butanol azeotropic distillation is the best method. The nanometer α-Al2O3 powder with non-aggregation can be manufactured using n-butanol azeotropic distillation and the average particle size is about 40 nm.展开更多
The Immersed Interface Method (IIM) is derived to solve the corresponding Fokker-Planck equation of Brownian motion with pure dry friction, which is one of the simplest models of piecewise-smooth stochastic systems. T...The Immersed Interface Method (IIM) is derived to solve the corresponding Fokker-Planck equation of Brownian motion with pure dry friction, which is one of the simplest models of piecewise-smooth stochastic systems. The IIM is capable of treating a discontinuity in the drift of Fokker-Planck equation and it is readily extended to the dry and viscous friction model. Analytic results of the considered model are used to confirm the effectiveness and design accuracy of the scheme.展开更多
The heating area of the material is large and the thermal efficiency is high,but it is n ecessary to control the suitable drying temperature ofdiffere nt medici nal materials to preserve the effective in gredients.D i...The heating area of the material is large and the thermal efficiency is high,but it is n ecessary to control the suitable drying temperature ofdiffere nt medici nal materials to preserve the effective in gredients.D iff ere nt kinds of Chinese medicine need different drying conditions to fulfill good drying requirements.Natural drying in the shade is one of the traditional drying methods,which takes a long time and is easily affected by the weather.The water volatilizes slowly.It is prone to mildew and discoloration during the drying process.However,it can better preserve the volatile oil components of Chinese medicine.The hot-air drying machine has lower requirements.The medicinal materials have a large heating area and high thermal efficiency,but it is necessary to control the appropriate drying temperature of different medicinal materials in order to preserve the active ingredients of the medicinal materials;it is not suitable for medicinal materials that stick and bind easily.The microwave drying method possesses superiority in drying some valuable medicinal materials such as Ren she n(Radix et Rhizoma Ginseng)and Lurong(Co「nu Cervi Pantotrichum),and the effective ingredients are preserved at a high degree;it can also achieve the purpose of killing enzymes and protecting glycosides and have a good bactericidal effect,but it is not suitable for Chinese medicines containing heat-sensitive ingredients,because it will destroy most of the proteins,amino acids,and peptides of Chinese medicine and result in the loss of efficacy.The far-infrared drying method is suitable for drying thin-layer medicinal materials and is friendly to the environment.Freeze-drying can preserve the active ingredients very well and greatly retain the efficacy,but it has obvious limitations in preserving some Chinese medicinal materials that need to kill enzymes and protect glycosides;besides,the cost is relatively high and the drying time is long.展开更多
[Objectives] To study the effects of different drying methods on quality of Chinese wolfberry powder. [Methods] The physical properties and nutritional contents of Chinese wolfberry powder prepared by hot air drying,v...[Objectives] To study the effects of different drying methods on quality of Chinese wolfberry powder. [Methods] The physical properties and nutritional contents of Chinese wolfberry powder prepared by hot air drying,vacuum freeze drying,microwave vacuum drying,drum drying and spray drying were measured and analyzed to explore the effects of different drying methods on quality characteristics of Chinese wolfberry powder. [Results] The total sugar content and reducing sugar contents of product: vacuum freeze drying > spray drying > microwave vacuum drying > drum drying > hot air drying; carotene and total flavonoid contents: vacuum freeze drying > microwave vacuum drying > spray drying > drum drying > hot air drying; after drying process,the dietary fiber content of product obtained by drum drying and spray drying was relatively higher,while the Vc content of Chinese wolfberry powder prepared by vacuum freeze drying was the highest. a~*value( redness to greenness) of color: vacuum freeze drying > microwave vacuum drying > spray drying > drum drying > hot air drying; the Chinese wolfberry powder prepared by vacuum freeze drying had the best solubility,hygroscopicity and rehydration ratio. [Conclusions] Microwave vacuum drying was the best method to prepare Chinese wolfberry powder,in order to keep its quality and consider the cost of production.展开更多
In this study, the Single Factor Test（SFT） was used to optimize the pre-freezing conditions of L. plantarum KLDS1.0391（KLDS1.0391）. Further, the Freeze-Drying Protective Agents（FDPA） of KLDS1.0391 was optimized ...In this study, the Single Factor Test（SFT） was used to optimize the pre-freezing conditions of L. plantarum KLDS1.0391（KLDS1.0391）. Further, the Freeze-Drying Protective Agents（FDPA） of KLDS1.0391 was optimized by Response Surface Methodology（RSM）. The optimum pretreatment conditions were as the follows： initial concentration of KLDS1.0391 was 1011 CFU · m L-1 and KLDS1.0391 was pre-freezed at –80℃ for 8 h to achieve the survival rate of 46.21%. The main components of FDPA were skim milk, sucrose, sodium glutamate and Tween-80. And the influence of four factors on the survival rate of KLDS1.0391 in freeze-drying was in order as the follows： skim milk〉sucrose〉Tween-80〉sodium glutamate. The optimal FDPA composition was skim milk 11.3%, sucrose 9.8%, sodium glutamate 5.1% and Tween-80 0.2%. Under the above conditions, the survival rate of the cells was 82.98%. Comparing the predicted values, the relative error was 0.37% and the difference was not significant, which indicated that the established model could effectively reflect the actual protection of FDPA to KLDS1.0391.展开更多
[Objectives] This paper was to clarify the effects of different drying methods on the physiological activities of kiwifruit,so as to provide theoretical bases for the drying processing of kiwifruit.[Methods]With kiwif...[Objectives] This paper was to clarify the effects of different drying methods on the physiological activities of kiwifruit,so as to provide theoretical bases for the drying processing of kiwifruit.[Methods]With kiwifruit as the research object,the effects of hot air drying,microwave drying,and vacuum freeze drying on the active ingredients in dried kiwifruit were studied,and antioxidant activity of the ingredients were determined through the scavenging capacity of 1,1-phenyl-2-picrylhydrazyl free radicals( DPPH),hydroxyl radical scavenging capacity and the antioxidant capacity of ferrous ions.[Results] Vacuum freeze drying greatly reduced the physiological activities of kiwifruit,followed by microwave drying.Hot air drying was the best choice for dehydration of kiwifruit.Under the same conditions,the total flavonoid content of kiwifruit from hot air drying was 70.12 mg/ml,and the DPPH· free radicals scavenging ability of the treatment solution was the strongest,with the scavenging rate reaching 9.42%.The OH radicals scavenging rate was the highest at the concentration of 0.015 mg/ml,reaching69.92%.The absorbance reached the maximum at the concentration of 0.025 mg/ml,and the ferrous ion reduction capacity was also the greatest with the absorbance of 2.542.[Conclusions] Hot air drying could well maintain the shape and nutrients of kiwifruit,making it a proper drying method for kiwifruit processing.展开更多
It was tried to prepare the microcapsules containing grape polyphenol with the spray drying method followed by the layer-by-layer method. As grape polyphenol was water soluble, the spray drying method was adopted to o...It was tried to prepare the microcapsules containing grape polyphenol with the spray drying method followed by the layer-by-layer method. As grape polyphenol was water soluble, the spray drying method was adopted to obtain the higher content. As the shell material of the first microcapsules prepared by the spray drying method, palmitic acid with the melting point of 60°C was adopted in order to prevent grape polyphenol from dissolution into water. As the shell material of the second microcapsules prepared by the layer-by-layer method, chitosan was used to coat the first microcapsules and to give the microcapsules alcohol resistance. In the experiment, the spray drying conditions such as the inlet temperature and the spraying pressure, the oil soluble surfactant species and the chitosan concentration were changed. The mean diameters of microcapsules could be controlled in the range from 5 μm to 35 μm by changing the spraying pressure and the inlet temperature. The yield of microcapsules and the microencapsulation efficiency over 50% could be obtained under the conditions of P = 1.0 kgf/cm2 and Tin = 100°C. Furthermore, the microencapsulation efficiency could be increased by adding the oil soluble surfactant with the larger HLB value. Coating with chitosan could considerably increase alcohol resistance.展开更多
It was tried to prepare temperature and water responsive microcapsules containing hydroquinone as a water soluble core material with the spray drying method. Microcapsules were composed of ethyl cellulose (EC), methyl...It was tried to prepare temperature and water responsive microcapsules containing hydroquinone as a water soluble core material with the spray drying method. Microcapsules were composed of ethyl cellulose (EC), methyl cellulose (MC) and P-N-isopropylacrylamid (PNIPAM). P-N-isopropylacrylamid and methyl cellulose were used as a temperature responsive polymer and as a water responsive polymer, respectively. Ethyl cellulose was the main shell material of microcapsule. At the microencapsulation process, the core and shell materials were dissolved in ethyl alcohol dissolving water (20 wt%) and then, spray-dried to prepare microcapsules. In the fundamental operation, the concentration and molecular weight of methyl cellulose were mainly changed. The releasing rate of hydroquinone was repressed at 40°C and increased at 20°C due to temperature responsive PNIPAM. Furthermore, responsibility to water was increased with the concentration of methyl cellulose.展开更多
Two-year-old Medicago sativa at budding initial stage was taken as research materials.Five methods were used to make green hay,including flatting stems ＋ spraying 2.5% K2CO3,flatting stems,sun curing,drying in shade ...Two-year-old Medicago sativa at budding initial stage was taken as research materials.Five methods were used to make green hay,including flatting stems ＋ spraying 2.5% K2CO3,flatting stems,sun curing,drying in shade and drying under 105 ℃ condition（CK）.Besides,effects of different green hay making methods on dry characteristics and nutritional quality of M.sativa green hay were studied,and a comprehensive evaluation of M.sativa green hays was conducted.Results showed that,except CK,the drying rates in other making methods were all fast at first,and then slow down.Both of drying under 105 ℃ condition and flatting stems ＋ spraying K2CO3 could speed up drying rate and reduce nutritional losses of green hay.Sun curing could also speed up drying rate,but it could not maintain the quality of green hay.The results of Grey Relational Analysis on five green hay making methods indicated that CK had the best comprehensive performance,followed by green hays made by flatting stems ＋ spraying K2CO3.Therefore,flatting stems ＋ spraying K2CO3 was a quick and easy method to make green hay,and it was worth to be recommended in practical production.展开更多
Dry friction damping structures are widely-used in aero-engines to mitigate vibration.The nonlinear nature of friction and the two-dimensional in-plane motion on the contact interface bring challenges to accurately an...Dry friction damping structures are widely-used in aero-engines to mitigate vibration.The nonlinear nature of friction and the two-dimensional in-plane motion on the contact interface bring challenges to accurately and efficiently predict the forced response of frictionally damped structures.The state-of-the-art Multi-Harmonic Balance Method(MHBM)on quasi-3D contact model in engineering cannot precisely capture the kinematics on the friction interface although the efficiency is high.The full-3D contact model can describe the constitutive relationship of the interface in a more accurate manner;however,the efficiency and convergence are not guaranteed for large-scale models.In this paper,a semi-analytical MHBM on full-3D contact model is proposed.The original Trajectory Tracking Method(TTM)for evaluating the contact force is reformulated to make the calculation more concise and the derivation of the Analytical Jacobian Matrix(AJM)feasible.Based on the chain rule of derivation,the AJM which is the core to upgrade the performance is deduced.Through a shrouded blade finite element model,the accuracy and efficiency of the proposed method are compared with both the MHBM on full-3D contact model with numerical Jacobian matrix and the MHBM on quasi-3D contact model with AJM.The results show that the AJM improves significantly the efficiency of the MHBM on full-3D contact model.The time cost of the proposed method is in the same order of magnitude as that of the MHBM on quasi-3D contact model.We also confirm that the full-3D contact model is necessary for the dynamic analyses of shrouded blades.If one uses the quasi-3D model,the estimation relative error of damping can even reach 31.8%in some cases.In addition,the AJM also brings benefits for stability analysis.It is highly recommended that engineers use the MHBM on full-3D contact model for the dynamic analysis and design of shrouded blades.展开更多
基金supported by the Deutsche Forschungsgemeinschaft(DFG)through project 429491391(BA 6878/1-1).
文摘Active Flux is a third order accurate numerical method which evolves cell averages and point values at cell interfaces independently.It naturally uses a continuous reconstruction,but is stable when applied to hyperbolic problems.In this work,the Active Flux method is extended for the first time to a nonlinear hyperbolic system of balance laws,namely,to the shallow water equations with bottom topography.We demonstrate how to achieve an Active Flux method that is well-balanced,positivity preserving,and allows for dry states in one spatial dimension.Because of the continuous reconstruction all these properties are achieved using new approaches.To maintain third order accuracy,we also propose a novel high-order approximate evolution operator for the update of the point values.A variety of test problems demonstrates the good performance of the method even in presence of shocks.
文摘BACKGROUND Dry eye disease(DED)represents a multifactorial condition characterized by ocular discomfort and visual disturbances.The management of DED relies heavily on accurate diagnosis to tailor effective treatments.Diagnostic approaches encompass both subjective and objective assessments.AIM To review the diagnostic methods used in the process of dry eye disease management.METHODS A comprehensive review of diagnostic approaches for dry eye was performed using scientific databases.Studies published within the last four years were considered.Studies were excluded if a full text was absent or the article was not written in English.Articles were assessed for relevancy,and a total of 107 studies were selected.The selection method used a systematic methodology,which guaranteed an exhaustive assessment of the diagnostic techniques reported in current literature.The study adheres to principles for systematic reviews ensuring dependability and accuracy.The studies were assessed for emphasize on both novel traditional and diagnostic methods for dry eye disease management.RESULTS Key objective tests include tear break-up time,which evaluates tear film stability;fluorescein and lissamine green staining,which assess ocular surface damage and inflammation;tear osmolarity measurement,indicative of tear film quality;and tear volume assessment via Schirmer's test,which evaluates tear production.Advanced imaging techniques such as optical coherence tomography and meibography offer detailed anatomical insights into the ocular surface and meibomian glands,aiding in the diagnosis of underlying structural abnormalities.Moreover,emerging technologies such as matrix metalloproteinase-9 testing and inflammatory biomarkers provide additional diagnostic precision,particularly in identifying inflammatory components of DED.CONCLUSION Integrating a combination of subjective and objective diagnostic tools allows clinicians to comprehensively assess the condition,tailor treatment plans,and monitor therapeutic efficacy.Continued advancements in diagnostic technologies promise to enhance our understanding and management of this prevalent ocular condition.
基金supported by Key Research and Development Program in Xizang Autonomous Region(XZ202301ZY0018N)Xizang Autonomous Region financial special project(XZCZ-SS-2024)+1 种基金the Science and Technology Program of Gansu Province(22JR5RA463)the Science and Technology Program of Guangdong Province(2023A0505050104)。
文摘Black wolfberry(Lycium ruthenicum)is enriched in phytochemical metabolites which can benefit human health.However,few studies have examined the effects of different fruit drying methods on its polyphenol content,antioxidant activity,and anti-inflammatory activity.In addition,whether and how consuming dried black wolfberry affects gut microbiota has not been reported.This study assessed the phytochemical profile and bioactivities of black wolfberry dried through different methods,and subsequently characterized changes in human fecal microbiota associated with freeze-dried black wolfberry in vitro.The results showed that freeze-dried samples retained higher total phenolics((49.68±1.62)mg GAE/g DM),tannins((38.64±1.35)mg GAE/g DM),and proanthocyanidins((3.35±0.30)mg/g DM)compared to sun drying or hot air drying(P<0.05),and exhibited higher antioxidant and anti-inflammatory activities.In human fecal inoculum bioreactor fermentations,freeze-dried black wolfberry was associated with increased species richness andα-diversity.At the genus level,fermentations treated with black wolfberry had a higher abundance of lactic acid bacteria including Lactococcus,Bifidobacterium,Lactobacillus,Pediococcus,and Weissella,as well as butyrate-producing bacteria compared to the untreated samples,suggesting enrichment for taxa associated with a healthy gut microbiome.In addition,the black wolfberry treatment group had higher levels of short-chain fatty acids,which were consistent with PICRUSt2 inference.This study defines an optimal method for black wolfberry preservation to retain the beneficial compounds,and provides a foundation for further exploration of its potential benefits for human gut microbiota.
基金Liaoning Provincial Department of Education Annual(2019)Scientific Research Fund Project(No.LSNZD201903)National Key R&D Program of China(No.2018YFD0400200)+1 种基金Liaoning Province,Shenyang Agricultural University,High-end Talent Introduction Fund Project(NO.SYAU20160003)Natural Science Foundation of Liaoning Province(No.20170540822).
文摘Suillus granulatus is a valuable wild edible mushroom with a strong umami taste.Different grades of S.granulatus were dried by different methods,including natural air drying(ND),hot air drying(HAD),vacuum drying(VD),and freeze drying(FD).Results showed that VD samples of all grades had the highest equivalent umami concentration(EUC)value(P<0.05).The second grade of ND samples showed the highest EUC value(P<0.05).The first grade of HAD samples showed the highest EUC value(P<0.05).The third grade of FD samples showed the highest EUC value(P<0.05).The third grade of VD samples had a higher EUC value than the other grades of samples dried by VD.Electronic tongue results indicated no significant differences between samples of all grades dried by all methods.Thus,umami taste components are affected by drying method and grade.VD is an appropriate drying method for all sample grades.ND,HAD,and FD are suitable for second-,first-,and third-grade samples,respectively.
基金Supported by Tangshan Science Project (19150204E)。
文摘[Objectives] This study was conducted to investigate the drying methods,functional and structure properties of dietary fiber( DF) from peanut shells.[Methods]Peanut shells were used as a raw material to prepare peanut shell dietary fiber( DF) by hot air drying( HA) and vacuum freeze drying( VF),respectively,and their functional and structural characteristics were compared in detail. [Results]The solubility,water holding capacity,oil holding capacity and swelling capacity of HA-DF and VF-DF were 2. 15 %,7. 63 g/g,7. 73 g/g,10. 35 ml/g and 3. 85 %,14. 98 g/g,15. 25 g/g,15. 85 ml/g,respectively. The total phenol contents were 2. 623 and 5. 173 mg GAE/g,respectively. The IC(50) values of ·OH,O2^-· and DPPH free radicals were 4. 16 and 4. 09 mg/ml,7. 90 and 3. 32 mg/ml,and 3. 19 and 3. 09 mg/ml,respectively. The molecular weight of VF-DF was smaller,and it had narrow molecular weight distribution and denser particles. Electron microscopy showed that VF-DF had a porous network like honeycomb and swelled structure. [Conclusions]This study can provide a theoretical basis for the functional modification and comprehensive utilization of peanut shell dietary fiber.
文摘Japanese pine, Korean pine and larch are three major softwood species in Korea. Their colors are relatively light, thus easily discolored due to drying and UV irradiation. In this study, they were dried with five different drying methods, steam treated and exposed to weathering. Their colors were measured using a spectrophotometer and comparisons made both among species and drying methods. For Japanese and Korean pines, high temperature dried and steam-dried specimens showed distinct color differences compared with the controls. Steam treatment discolored the dried specimens of Japanese and Korean pines but did not discolor those of larch. After weathering for 144 days the specimens of Japanese pine showed slight color differences among drying methods.
文摘The porous spherical LiFePO4/C powders were prepared by spray drying and carbothermal method （SDCTM）. Cheaper trivalent iron ion was used as the precursor. The pure olivine phase can be prepared with the spray drying and subsequent heat-treatment. The average particle size is around 10μm, and the value of porosity is 63.04%. The results indicate that the initial discharge capacity decreases with increasing charge/ discharge rate and reduces from 138.8 mAh · g^-1 at C/20 rate to 98.3 mAh ·g^-1 at 2C rate, while the polarization between the charge and discharge plateaux is enlarged from 53 mv to 347 mv. However, the average discharge efficiency is up to 99.5% at 2C rate compared to 80.6% at C/20 rate from the second cycle.
基金the National Natural Science Foundation of China (Grant No.10702050)the Natural Science Foundation of Tianjin (Grant No.07JCYBJC07500)the Support Plan of Science and Technology of Tianjin (Grant No.07ZCGYSH01700)
文摘A particular porosity method named ＂slot method＂ is implemented in a depth-integrated shallow water flow model （DIVAST） to simulate wetting and drying processes. Discussed is the relationship between the shape factors of the ＂slot＂ and the preset depth used in ＂wetting-drying＂ algorithm. Two typical tests are conducted to examine the performance of the method with the effect of the shape factors of the ＂slot＂ being checked in detail in the first test. Numerical results demonstrate that： 1 ） no additional effort to improve the finite difference scheme is needed to implement ＂slot method＂ in DIVAST, and 2） ＂slot method＂ will simulate wetting and diying processes correctly if the shape factors of the ＂slot＂ being selected properly.
基金financially supported by the National Key Technology R&D Program in the 11~(th) Five Year Plan of China(2006BAD12B01)Special Public Sector Fund in Agriculture(200903006)
文摘Background：This experiment was conducted to determine the nutritive value of corn from the north of China for growing pigs.The experiment examined corn variety（LS1,LS2,LS3 and LS4）grown in one location,drying method（sun dried and artificially dried）and different drying temperatures.Corn harvested at 20-25%moisture was dried to about 12%moisture by sun drying and artificially drying at 80,100,or 120℃ in a fluidized bed dryer.Ninety-six barrows（average BW of 33.4 ± 2.7 kg）were housed in individual metabolism crates to facilitate separate collection of feces and urine.A five-day collection period followed a seven-day diet acclimation period.Results：The results indicated that variety significantly influenced（P〈0.01）the 1,000 kernel weight of corn but not the bulk weight.Variety also influenced the available energy content（digestible energy of dry matter,P〈0.01;metabolisable energy of dry matter,P〈0.01）and digestibility of organic matter（P〈0.01）,as well as dry matter（P〈0.01）and gross energy（GE）content（P〈0.02）.The drying method of corn significantly influenced the 1,000 kernel weight（P〈0.01）,bulk weight（P〈0.01）and digestibility of ether extract（EE）（P〈0.01）.No effect of drying temperature on the digestibility of organic matter,dry matter（DM）,crude protein（CP）,neutral detergent fiber（NDF）,acid detergent fiber（ADF）and gross energy was observed,but gelatinization（P〈0.05）and test weight（P〈0.01）decreased with an increase in temperature.Conclusions：Variety has a significant impact on the nutritive value of corn for growing pigs,and greater attention needs to be paid to these influences in the assignment of the nutritive value of corn given to growing pigs.
基金Project (5JJ30103) supported by the Natural Science Foundation of Hunan Province, China
文摘Ammonium aluminum carbonate hydroxide (AACH) precursor was synthesized by the precipitation reaction of aluminum sulfate and ammonium carbonate. Then the precursor was dealt with five drying methods including ordinary drying, alcohol exchange, vacuum freeze-drying, glycol distillation, n-butanol azeotropic distillation respectively and calcined at 1 200 ℃ for 2 h to get α-Al2O3. The effects of drying methods on preparation of nanometer α-Al2O3 were discussed, and the optimal drying method was confirmed. The structural properties of powders were characterized by XRD, SEM and BET measurements. The results show that vacuum freeze-drying, glycol distillation and n-butanol azeotropic distillation can prevent the powders from aggregating, and among them the n-butanol azeotropic distillation is the best method. The nanometer α-Al2O3 powder with non-aggregation can be manufactured using n-butanol azeotropic distillation and the average particle size is about 40 nm.
文摘The Immersed Interface Method (IIM) is derived to solve the corresponding Fokker-Planck equation of Brownian motion with pure dry friction, which is one of the simplest models of piecewise-smooth stochastic systems. The IIM is capable of treating a discontinuity in the drift of Fokker-Planck equation and it is readily extended to the dry and viscous friction model. Analytic results of the considered model are used to confirm the effectiveness and design accuracy of the scheme.
文摘The heating area of the material is large and the thermal efficiency is high,but it is n ecessary to control the suitable drying temperature ofdiffere nt medici nal materials to preserve the effective in gredients.D iff ere nt kinds of Chinese medicine need different drying conditions to fulfill good drying requirements.Natural drying in the shade is one of the traditional drying methods,which takes a long time and is easily affected by the weather.The water volatilizes slowly.It is prone to mildew and discoloration during the drying process.However,it can better preserve the volatile oil components of Chinese medicine.The hot-air drying machine has lower requirements.The medicinal materials have a large heating area and high thermal efficiency,but it is necessary to control the appropriate drying temperature of different medicinal materials in order to preserve the active ingredients of the medicinal materials;it is not suitable for medicinal materials that stick and bind easily.The microwave drying method possesses superiority in drying some valuable medicinal materials such as Ren she n(Radix et Rhizoma Ginseng)and Lurong(Co「nu Cervi Pantotrichum),and the effective ingredients are preserved at a high degree;it can also achieve the purpose of killing enzymes and protecting glycosides and have a good bactericidal effect,but it is not suitable for Chinese medicines containing heat-sensitive ingredients,because it will destroy most of the proteins,amino acids,and peptides of Chinese medicine and result in the loss of efficacy.The far-infrared drying method is suitable for drying thin-layer medicinal materials and is friendly to the environment.Freeze-drying can preserve the active ingredients very well and greatly retain the efficacy,but it has obvious limitations in preserving some Chinese medicinal materials that need to kill enzymes and protect glycosides;besides,the cost is relatively high and the drying time is long.
基金Supported by National Science and Technology Support Plan Program(2016-YFD0400704-3)
文摘[Objectives] To study the effects of different drying methods on quality of Chinese wolfberry powder. [Methods] The physical properties and nutritional contents of Chinese wolfberry powder prepared by hot air drying,vacuum freeze drying,microwave vacuum drying,drum drying and spray drying were measured and analyzed to explore the effects of different drying methods on quality characteristics of Chinese wolfberry powder. [Results] The total sugar content and reducing sugar contents of product: vacuum freeze drying > spray drying > microwave vacuum drying > drum drying > hot air drying; carotene and total flavonoid contents: vacuum freeze drying > microwave vacuum drying > spray drying > drum drying > hot air drying; after drying process,the dietary fiber content of product obtained by drum drying and spray drying was relatively higher,while the Vc content of Chinese wolfberry powder prepared by vacuum freeze drying was the highest. a~*value( redness to greenness) of color: vacuum freeze drying > microwave vacuum drying > spray drying > drum drying > hot air drying; the Chinese wolfberry powder prepared by vacuum freeze drying had the best solubility,hygroscopicity and rehydration ratio. [Conclusions] Microwave vacuum drying was the best method to prepare Chinese wolfberry powder,in order to keep its quality and consider the cost of production.
基金Supported by the Outstanding Youth Scientists Foundation of Harbin City(2014RFYXJ006)
文摘In this study, the Single Factor Test（SFT） was used to optimize the pre-freezing conditions of L. plantarum KLDS1.0391（KLDS1.0391）. Further, the Freeze-Drying Protective Agents（FDPA） of KLDS1.0391 was optimized by Response Surface Methodology（RSM）. The optimum pretreatment conditions were as the follows： initial concentration of KLDS1.0391 was 1011 CFU · m L-1 and KLDS1.0391 was pre-freezed at –80℃ for 8 h to achieve the survival rate of 46.21%. The main components of FDPA were skim milk, sucrose, sodium glutamate and Tween-80. And the influence of four factors on the survival rate of KLDS1.0391 in freeze-drying was in order as the follows： skim milk〉sucrose〉Tween-80〉sodium glutamate. The optimal FDPA composition was skim milk 11.3%, sucrose 9.8%, sodium glutamate 5.1% and Tween-80 0.2%. Under the above conditions, the survival rate of the cells was 82.98%. Comparing the predicted values, the relative error was 0.37% and the difference was not significant, which indicated that the established model could effectively reflect the actual protection of FDPA to KLDS1.0391.
基金Supported by the Quality Project of Shanxi Normal University(2017YZKC-06)
文摘[Objectives] This paper was to clarify the effects of different drying methods on the physiological activities of kiwifruit,so as to provide theoretical bases for the drying processing of kiwifruit.[Methods]With kiwifruit as the research object,the effects of hot air drying,microwave drying,and vacuum freeze drying on the active ingredients in dried kiwifruit were studied,and antioxidant activity of the ingredients were determined through the scavenging capacity of 1,1-phenyl-2-picrylhydrazyl free radicals( DPPH),hydroxyl radical scavenging capacity and the antioxidant capacity of ferrous ions.[Results] Vacuum freeze drying greatly reduced the physiological activities of kiwifruit,followed by microwave drying.Hot air drying was the best choice for dehydration of kiwifruit.Under the same conditions,the total flavonoid content of kiwifruit from hot air drying was 70.12 mg/ml,and the DPPH· free radicals scavenging ability of the treatment solution was the strongest,with the scavenging rate reaching 9.42%.The OH radicals scavenging rate was the highest at the concentration of 0.015 mg/ml,reaching69.92%.The absorbance reached the maximum at the concentration of 0.025 mg/ml,and the ferrous ion reduction capacity was also the greatest with the absorbance of 2.542.[Conclusions] Hot air drying could well maintain the shape and nutrients of kiwifruit,making it a proper drying method for kiwifruit processing.
文摘It was tried to prepare the microcapsules containing grape polyphenol with the spray drying method followed by the layer-by-layer method. As grape polyphenol was water soluble, the spray drying method was adopted to obtain the higher content. As the shell material of the first microcapsules prepared by the spray drying method, palmitic acid with the melting point of 60°C was adopted in order to prevent grape polyphenol from dissolution into water. As the shell material of the second microcapsules prepared by the layer-by-layer method, chitosan was used to coat the first microcapsules and to give the microcapsules alcohol resistance. In the experiment, the spray drying conditions such as the inlet temperature and the spraying pressure, the oil soluble surfactant species and the chitosan concentration were changed. The mean diameters of microcapsules could be controlled in the range from 5 μm to 35 μm by changing the spraying pressure and the inlet temperature. The yield of microcapsules and the microencapsulation efficiency over 50% could be obtained under the conditions of P = 1.0 kgf/cm2 and Tin = 100°C. Furthermore, the microencapsulation efficiency could be increased by adding the oil soluble surfactant with the larger HLB value. Coating with chitosan could considerably increase alcohol resistance.
文摘It was tried to prepare temperature and water responsive microcapsules containing hydroquinone as a water soluble core material with the spray drying method. Microcapsules were composed of ethyl cellulose (EC), methyl cellulose (MC) and P-N-isopropylacrylamid (PNIPAM). P-N-isopropylacrylamid and methyl cellulose were used as a temperature responsive polymer and as a water responsive polymer, respectively. Ethyl cellulose was the main shell material of microcapsule. At the microencapsulation process, the core and shell materials were dissolved in ethyl alcohol dissolving water (20 wt%) and then, spray-dried to prepare microcapsules. In the fundamental operation, the concentration and molecular weight of methyl cellulose were mainly changed. The releasing rate of hydroquinone was repressed at 40°C and increased at 20°C due to temperature responsive PNIPAM. Furthermore, responsibility to water was increased with the concentration of methyl cellulose.
基金Supported by Tibet High Quality Freeze Resistance Bluegrass Varieties Breeding(Z2013C02N02_02)National Wool Sheep Grazing Grassland Ecological Position of Scientific Research Project(CARS-40-09B)
文摘Two-year-old Medicago sativa at budding initial stage was taken as research materials.Five methods were used to make green hay,including flatting stems ＋ spraying 2.5% K2CO3,flatting stems,sun curing,drying in shade and drying under 105 ℃ condition（CK）.Besides,effects of different green hay making methods on dry characteristics and nutritional quality of M.sativa green hay were studied,and a comprehensive evaluation of M.sativa green hays was conducted.Results showed that,except CK,the drying rates in other making methods were all fast at first,and then slow down.Both of drying under 105 ℃ condition and flatting stems ＋ spraying K2CO3 could speed up drying rate and reduce nutritional losses of green hay.Sun curing could also speed up drying rate,but it could not maintain the quality of green hay.The results of Grey Relational Analysis on five green hay making methods indicated that CK had the best comprehensive performance,followed by green hays made by flatting stems ＋ spraying K2CO3.Therefore,flatting stems ＋ spraying K2CO3 was a quick and easy method to make green hay,and it was worth to be recommended in practical production.
基金financially supported by the National Natural Science Foundation of China(Nos.52175071,91860205)the Major Projects of Aero-engines and Gas turbines(No.J2019-IV-023-0091)。
文摘Dry friction damping structures are widely-used in aero-engines to mitigate vibration.The nonlinear nature of friction and the two-dimensional in-plane motion on the contact interface bring challenges to accurately and efficiently predict the forced response of frictionally damped structures.The state-of-the-art Multi-Harmonic Balance Method(MHBM)on quasi-3D contact model in engineering cannot precisely capture the kinematics on the friction interface although the efficiency is high.The full-3D contact model can describe the constitutive relationship of the interface in a more accurate manner;however,the efficiency and convergence are not guaranteed for large-scale models.In this paper,a semi-analytical MHBM on full-3D contact model is proposed.The original Trajectory Tracking Method(TTM)for evaluating the contact force is reformulated to make the calculation more concise and the derivation of the Analytical Jacobian Matrix(AJM)feasible.Based on the chain rule of derivation,the AJM which is the core to upgrade the performance is deduced.Through a shrouded blade finite element model,the accuracy and efficiency of the proposed method are compared with both the MHBM on full-3D contact model with numerical Jacobian matrix and the MHBM on quasi-3D contact model with AJM.The results show that the AJM improves significantly the efficiency of the MHBM on full-3D contact model.The time cost of the proposed method is in the same order of magnitude as that of the MHBM on quasi-3D contact model.We also confirm that the full-3D contact model is necessary for the dynamic analyses of shrouded blades.If one uses the quasi-3D model,the estimation relative error of damping can even reach 31.8%in some cases.In addition,the AJM also brings benefits for stability analysis.It is highly recommended that engineers use the MHBM on full-3D contact model for the dynamic analysis and design of shrouded blades.
