Linear transfer function approximations of the fractional integrators 1Is~ with m ^- 0.80-0.99 with steps of 0.01 are calculated systemically from the fractional order calculus and frequency-domain approximation metho...Linear transfer function approximations of the fractional integrators 1Is~ with m ^- 0.80-0.99 with steps of 0.01 are calculated systemically from the fractional order calculus and frequency-domain approximation method. To illustrate the effectiveness for fractional functions, the magnitude Bode diagrams of the actual and approximate transfer functions 1Ism with a slope of -20m dB//decade are depicted. By using the transfer function approxima- tions of the fractional integrators, a new fractional-order nonlinear system is investigated through the bifurcation diagram and Lyapunov exponent. The corresponding circuit of the fractional-order system is designed and the experimental results match perfectly with the numerical simulations.展开更多
NTRU is a lattice-based public key cryptosystem featuring reasonably short, easily created keys, high speed, and low memory requirements, seems viable for wireless network. This paper presents two optimized designs ba...NTRU is a lattice-based public key cryptosystem featuring reasonably short, easily created keys, high speed, and low memory requirements, seems viable for wireless network. This paper presents two optimized designs based on the enhanced NTRU algorithm. One is a light-weight and fast NTRU core, it performs encryption only. This work has a gate-count of 1175 gates and a power consumption of 1.51 μW. It can finish the whole encryption process in 1498 μs at 500 kHz. As such, it is perfect for wireless sensor network. Another high-speed NTRU core is capable of both encryption and decryption, with delays of 16,064 μs and 128,010 μs in encryption and decryption respectively. Moreover, it consists of 25,758 equivalent gates and has a total power consumption of 59.2 μW (it will be reduced greatly if low power methods were adopted). This core is recommended to be used in base stations or servers in wireless network.展开更多
The paper is focused on available server management in Internet connected network environments. The local backup servers are hooked up by LAN and replace broken main server immediately and several different types of b...The paper is focused on available server management in Internet connected network environments. The local backup servers are hooked up by LAN and replace broken main server immediately and several different types of backup servers are also considered. The remote backup servers are hooked up by VPN (Virtual Private Network) with high-speed optical network. A Virtual Private Network (VPN) is a way to use a public network infrastructure and hooks up long-distance servers within a single network infrastructure. The remote backup servers also replace broken main severs immediately under the different conditions with local backups. When the system performs a mandatory routine maintenance of main and local backup servers, auxiliary servers from other location are being used for backups during idle periods. Analytically tractable results are obtained by using several mathematical techniques and the results are demonstrated in the framework of optimized networked server allocation problems. The operational workflow give the guidelines for the actual implementations.展开更多
The advances of digital arithmetic techniques permit computer designers to implement high speed application specific chips. The currently produced digital circuits have demonstrated high performance in terms of severa...The advances of digital arithmetic techniques permit computer designers to implement high speed application specific chips. The currently produced digital circuits have demonstrated high performance in terms of several criteria, such as, high clock rate, short input/output delay, small silicon area, and low power dissipation. In this paper, we implement several sinusoidal generation methods to optimize their performance and output using advanced digital arithmetic techniques. In this paper, the implementations of advanced digital oscillator structures with and without pipelining are proposed. The synthesis results of the implementation with pipelining have proven that it is superior to other sinusoidal generation methods in terms of the maximum frequency and signal resolution. Hence, this method is used in the design of the proposed digital oscillator chip.展开更多
With the rapid development of quantum theory and technology in recent years,especially the emergence of some quantum cloud computing platforms,more and more researchers are not satisfied with the theoretical derivatio...With the rapid development of quantum theory and technology in recent years,especially the emergence of some quantum cloud computing platforms,more and more researchers are not satisfied with the theoretical derivation and simulation verification of quantum computation(especially quantum algorithms),experimental verification on real quantum devices has become a new trend.In this paper,three representative quantum algorithms,namely Deutsch-Jozsa,Grover,and Shor algorithms,are briefly depicted,and then their implementation circuits are presented,respectively.We program these circuits on python with QISKit to connect the remote real quantum devices(i.e.,ibmqx4,ibmqx5)on IBM Q to verify these algorithms.The experimental results not only show the feasibility of these algorithms,but also serve to evaluate the functionality of these devices.展开更多
This article examines vulnerabilities to power analysis attacks between software and hardware implementations of cryptographic algorithms. Representative platforms including an Atmel 89S8252 8-bit processor and a 0.25...This article examines vulnerabilities to power analysis attacks between software and hardware implementations of cryptographic algorithms. Representative platforms including an Atmel 89S8252 8-bit processor and a 0.25 um 1.8 v standard cell circuit are proposed to implement the advance encryption standard （AES）. A simulation-based experimental environment is built to acquire power data, and single-bit differential power analysis （DPA）, and multi-bit DPA and correlation power analysis （CPA） attacks are conducted on two implementations respectively. The experimental results show that the hardware implementation has less data-dependent power leakages to resist power attacks. Furthermore, an improved DPA approach is proposed. It adopts hamming distance of intermediate results as power model and arranges plaintext inputs to differentiate power traces to the maximal probability. Compared with the original power attacks, our improved DPA performs a successful attack on AES hardware implementations with acceptable power measurements and fewer computations.展开更多
Objective:This review aimed to identify the barriers and facilitators to equitable coronavirus disease 2019(COVID-19)vaccine distribution in Nigeria using the consolidated framework for implementation research(CFIR).M...Objective:This review aimed to identify the barriers and facilitators to equitable coronavirus disease 2019(COVID-19)vaccine distribution in Nigeria using the consolidated framework for implementation research(CFIR).Methods:A comprehensive search strategy was applied across five databases—Web of Science,MEDLINE,EMBASE,CAB Direct,and CINAHL.The search,conducted as part of a scoping review,yielded 2,751 citations.Seven studies met the inclusion criteria after screening.Data were extracted and analyzed using CFIR constructs to identify key barriers and facilitators to equitable vaccine distribution.Results:Six barriers were identified:limited physical and socioeconomic access,bribery,nepotism,and insufficient availability of translated information.Facilitators included community involvement as local monitoring agents,unannounced staff inspections,healthcare worker training tailored to community needs,and localized outreach strategies such as jingles and call-in programs.CFIR constructs,including Local Conditions,Tailoring Strategies,Available Resources,and Physical Infrastructure,provided a framework for analyzing the findings.Conclusion:This review highlights significant barriers and promising facilitators to equitable vaccine distribution in Nigeria.Targeted interventions,such as community engagement,anti-corruption measures,and culturally tailored strategies,are critical to addressing these challenges and improving access.These findings underscore the need for localized,equity-focused approaches to enhance vaccine distribution systems in Nigeria and other low-resource settings.展开更多
The Royal Tropical Institute(KIT)in Amsterdam is an independent centre of knowledge and expertise in the areas of international and intercultural cooperation,operating at the interface between theory and practice and ...The Royal Tropical Institute(KIT)in Amsterdam is an independent centre of knowledge and expertise in the areas of international and intercultural cooperation,operating at the interface between theory and practice and between policy and implementation.The Institute contributes to sustainable development,poverty alleviation and cultural preservation and exchange.展开更多
Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds tha...Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds that the low-altitude economy can effectively promote the development of high-end and diversified tourism in Zhejiang by innovating tourism formats,optimizing resource allocation,and enhancing tourist experiences.Besides,it analyzes the current development status of the low-altitude economy in Zhejiang and its potential for integration with tourism,revealing specific enabling pathways for tourism transformation,including low-altitude sightseeing,aviation tourism,and low-altitude sports.Finally,it proposes policy recommendations such as strengthening policy support,enhancing infrastructure development,and cultivating market entities.The findings aim to provide theoretical references and practical guidance for the high-quality development of tourism in Zhejiang Province.展开更多
Digital health is transforming healthcare by integrating advanced technologies to make healthcare more accessible,efficient,and personalized.From electronic health records,telemedicine,wearable devices,and artificial ...Digital health is transforming healthcare by integrating advanced technologies to make healthcare more accessible,efficient,and personalized.From electronic health records,telemedicine,wearable devices,and artificial intelligence to the recent smart hospitals,digital health is improving patient care and outcomes while reducing healthcare costs.However,the integration of digital health faces several challenges,including data privacy,cybersecurity risks,and inequitable access to technology.This article provides an overview of the current state of digital health,key challenges in implementation,and potential solutions to maximize the benefits of digital health and ensure efficient,equitable,and patient‐centered healthcare in the future.展开更多
The vonoprazan(VPZ)triple therapy regimen for Helicobacter pylori(H.pylori)eradication developed by Han et al employs a scientifically rigorous clinical trial design.This multicenter randomized controlled trial establ...The vonoprazan(VPZ)triple therapy regimen for Helicobacter pylori(H.pylori)eradication developed by Han et al employs a scientifically rigorous clinical trial design.This multicenter randomized controlled trial establishes a standardized treatment framework aimed at improving H.pylori eradication rates,focusing on simplifying treatment regimens,shortening therapy duration,and optimizing therapeutic outcomes.The core of clinical translation lies in improving drug accessibility,establishing multidimensional safety evaluation systems,and optimizing cost-effectiveness.Conducting regional adaptability studies and comprehensive safety assessments is crucial for enhancing VPZ regimen effectiveness in China’s diverse healthcare environments.This study provides important evidence-based support for optimizing H.pylori treatment strategies in China,though further validation of universal applicability for nationwide implementation remains necessary.展开更多
Language policies are of great significance to a nation’s stability,unity,and development.Uzbekistan’s language policies have reflected the political,economic,and cultural dynamics of different periods throughout hi...Language policies are of great significance to a nation’s stability,unity,and development.Uzbekistan’s language policies have reflected the political,economic,and cultural dynamics of different periods throughout historical changes,influencing social structures and ethnic relations.This paper summarizes the characteristics of Uzbekistan’s language policies in different eras:During the Tsarist Russian period,the Russification of language policies hindered the development of local languages;in the Soviet era,policies adopted a dual approach,promoting both Russian and prioritizing ethnic languages;after independence,Uzbekistan established Uzbek as the state language and emphasized foreign language education.The current language policy in Uzbekistan presents a complex landscape:While emphasizing the dominant role of the national language helps preserve its heritage,it may easily spark ethnic and political tensions;promoting pluralism and inclusivity brings benefits but faces challenges in balancing language statuses,resource allocation,management,and communication;modernization efforts encounter difficulties in standardizing dialects and foreign loanwords;and in international exchanges,there is a need to balance relations with global lingua francas.In conclusion,Uzbekistan’s language policies have undergone unique transformations and face numerous challenges.In-depth research is crucial for improving the country’s policies and enhancing China-Uzbekistan cooperation.Proactive measures are needed to address these challenges,ensuring the sustainability of language policies and fostering greater national prosperity.展开更多
Kang et al published a study recently in the World Journal of Gastroenterology introducing an interpretable machine learning model to predict anastomotic leakage after rectal cancer surgery,highlighting postoperative ...Kang et al published a study recently in the World Journal of Gastroenterology introducing an interpretable machine learning model to predict anastomotic leakage after rectal cancer surgery,highlighting postoperative serum calcium as a key predictive feature.While this represents a significant advancement,we argue that reliance on a static calcium threshold may limit clinical applicability.We advocate for a dynamic,trajectory-based assessment of serum calcium levels across perioperative time points,using modeling approaches such as time-series regression or mixed-effects models.Furthermore,the model’s robustness could be improved by incorporating systemic inflammation and nutritional indices such as C-reactive protein,procalcitonin,the neutrophil-to-lymphocyte ratio,and the systemic immune-inflammation index,supported by recent prospective studies.Finally,generalizability remains a concern,warranting broader validation and clearer clinical deployment strategies.By addressing these aspects,the model’s clinical translation and decision-making impact could be substantially enhanced.展开更多
The efficient implementation of the Advanced Encryption Standard(AES)is crucial for network data security.This paper presents novel hardware implementations of the AES S-box,a core component,using tower field represen...The efficient implementation of the Advanced Encryption Standard(AES)is crucial for network data security.This paper presents novel hardware implementations of the AES S-box,a core component,using tower field representations and Boolean Satisfiability(SAT)solvers.Our research makes several significant contri-butions to the field.Firstly,we have optimized the GF(24)inversion,achieving a remarkable 31.35%area reduction(15.33 GE)compared to the best known implementations.Secondly,we have enhanced multiplication implementa-tions for transformation matrices using a SAT-method based on local solutions.This approach has yielded notable improvements,such as a 22.22%reduction in area(42.00 GE)for the top transformation matrix in GF((24)2)-type S-box implementation.Furthermore,we have proposed new implementations of GF(((22)2)2)-type and GF((24)2)-type S-boxes,with the GF(((22)2)2)-type demonstrating superior performance.This implementation offers two variants:a small area variant that sets new area records,and a fast variant that establishes new benchmarks in Area-Execution-Time(AET)and energy consumption.Our approach significantly improves upon existing S-box implementations,offering advancements in area,speed,and energy consumption.These optimizations contribute to more efficient and secure AES implementations,potentially enhancing various cryptographic applications in the field of network security.展开更多
Early childhood character education is a critical element in shaping an individual’s moral foundation and fostering a sense of social responsibility.It plays a fundamental role in overall personal development.Althoug...Early childhood character education is a critical element in shaping an individual’s moral foundation and fostering a sense of social responsibility.It plays a fundamental role in overall personal development.Although China’s early childhood character education has made progress with the support of policies and practical exploration,it still faces challenges such as the homogenization of educational models,a formalization of home-kindergarten cooperation,a single-dimensional evaluation system,and a need for further improvement in teachers’professional competence in character education.This paper draws on core theories of character education(e.g.,social learning theory and cognitive moral development theory)and incorporates representative case studies to conduct an in-depth analysis of the current landscape and associated challenges.It proposes innovative approaches,which include establishing a“threefold”system of implementation,enhancing the mechanisms for home-kindergarten co-education,optimizing and ensuring a multidimensional and dynamic evaluation system,equitably allocating teaching resources,and expanding the social support networks.The aim is to offer theoretical reference and practical solutions to promote the scientific and systematic development of early childhood character education.展开更多
Both the complex geometrical morphology of rough-walled rock fractures and the nonlinearity of fluid flow contribute to resistance in fluid flow through rock fractures.The interactions of the shear-flow process furthe...Both the complex geometrical morphology of rough-walled rock fractures and the nonlinearity of fluid flow contribute to resistance in fluid flow through rock fractures.The interactions of the shear-flow process further complicate the characterisation of flow behaviours in rock fractures.In this study,an improved friction factor model involving both the effects of viscous and inertial forces is presented based on the Forchheimer equation.The model incorporates two key variables,i.e.Reynolds number and relative roughness,which reflect the effects of flow regimes and fracture roughness,respectively.The changes in geometrical parameters induced by shearing are considered,with the peak asperity height predicted through a correlation with post-peak roughness degradation.The hydraulic aperture during shearing is estimated using a suggested equation that accounts for the mobilised contact area ratio and variable aperture distribution.The parametric sensitivity analysis reveals that shear-induced changes in fracture geometry enhance the flow nonlinearity in rock fractures.The model performs well in predicting the friction factor based on two validation criteria.Then,the proposed friction factor model is incorporated into the three-dimensional distinct element code(3DEC)in the form of the Darcy-Weisbach equation.Coupled with the numerically implemented mechanical model and hydraulic aperture prediction model,numerical simulations of coupled shear-flow processes in single rock fractures are conducted.The simulation outcomes are validated through comparison with the experimental results,showing acceptable agreement and demonstrating that the numerical model is capable of accurately evaluating the hydro-mechanical coupling behaviour during the shearing of rock fractures.展开更多
As an emerging technological form,the metaverse provides innovative transformations for all levels of education-including scenarios,resources,and models-through its highly immersive and powerful social interaction cha...As an emerging technological form,the metaverse provides innovative transformations for all levels of education-including scenarios,resources,and models-through its highly immersive and powerful social interaction characteristics.Educational evaluation is core to assessing teaching effects and improving teaching strategies.With the technical support of the metaverse,challenges in traditional educational evaluation can be addressed,and comprehensive multi-dimensional portraits of individuals and collectives can be depicted,effectively enhancing teaching outcomes.Therefore,it has important value and untapped potential.This paper first analyzes the characteristics of educational evaluation in the metaverse context,discusses possible opportunities and challenges,then explores comprehensive practical paths from macro,meso,and micro levels,providing suggestions for the reform of educational evaluation in the metaverse environment.展开更多
Oncology covers a wide range of knowledge and is more difficult compared to other clinical disciplines.Therefore,it is crucial to seek an efficient teaching method for oncology education.In recent years,China’s inter...Oncology covers a wide range of knowledge and is more difficult compared to other clinical disciplines.Therefore,it is crucial to seek an efficient teaching method for oncology education.In recent years,China’s internet technology has achieved rapid development.Massive Open Online Course(MOOC),a blended learning approach based on internet technology,has strong applicability to medical education.It can not only improve teaching quality but also promote further reform of the discipline.Based on this,our study searched for relevant research at home and abroad and reviewed the implementation path of integrating MOOC and blended learning in oncology education.This provides a theoretical foundation for the innovation of oncology teaching models,improves the level of oncology teaching,and lays a solid foundation for talent reserves in oncology departments.展开更多
In the wave of higher education internationalization,college students’career education is faced with problems such as inadequate integration of international elements in teaching content,insufficient depth of interna...In the wave of higher education internationalization,college students’career education is faced with problems such as inadequate integration of international elements in teaching content,insufficient depth of international cooperation in practical links,lack of international professional experience among the teaching staff,and insufficient emphasis on the cultivation of multicultural adaptability in the education model.Based on this,this paper deeply explores the new requirements put forward by internationalization for college students’career education and its diversified implementation paths from the perspective of higher education internationalization.It aims to build a comprehensive and multi-level career education system and improve students’international competitiveness through strategies such as constructing an internationalized curriculum system,expanding international cooperation practice projects,strengthening international exchanges and training for teachers,and integrating multicultural education.展开更多
Background:Community-based first responders face high levels of workplace stressors that can pro-foundly impact their physical and mental health.Mindfulness-based interventions have shown promise in decreasing stress ...Background:Community-based first responders face high levels of workplace stressors that can pro-foundly impact their physical and mental health.Mindfulness-based interventions have shown promise in decreasing stress and increasing psychological resilience;however,implementation is difficult due to unpredictability of the job,department culture,and generational preferences.The objective of this qualitative study was to identify and enhance understanding of the specific needs and potential barriers and facilitators for the implementation of mindfulness-based programming for community-based first responders.Methods:A phenomenological qualitative study design was used to gain insights into the lived experiences of first responders and elicit perceptions regarding barriers and facilitators for engaging in mindfulness activities.During virtual semi-structured interviews,eleven career firefighters and emergency medical service(EMS)providers offered feedback relative to worksite mindfulness practices,and the use of a stress reduction smartphone application.The Consolidated Framework for Implementation Research was used to guide the analysis relative to barriers and facilitators of implementation success and sustainability.Results:First responders expressed openness to mindfulness-based interventions and a smartphone app that would provide stress reduction content,however,they were adamant that programming needed to be accessible and easily integrated into their workday.They also reinforced that organizational culture and leadership support for their health and well-being were overarching factors essential for implementation success.Conclusions:First responders were supportive of evidence-based mindfulness practices,optimally developed and/or facilitated by someone with intimate knowledge of their unique work environments and challenges.Organizational culture and leadership support were essential for implementation success and sustainability.展开更多
基金Supported by the National Natural Science Foundation of China under Grant No 51475246the Natural Science Foundation of Jiangsu Province under Grant No Bk20131402the Ministry-of-Education Overseas Returnees Start-up Research Fund under Grant No[2012]1707
文摘Linear transfer function approximations of the fractional integrators 1Is~ with m ^- 0.80-0.99 with steps of 0.01 are calculated systemically from the fractional order calculus and frequency-domain approximation method. To illustrate the effectiveness for fractional functions, the magnitude Bode diagrams of the actual and approximate transfer functions 1Ism with a slope of -20m dB//decade are depicted. By using the transfer function approxima- tions of the fractional integrators, a new fractional-order nonlinear system is investigated through the bifurcation diagram and Lyapunov exponent. The corresponding circuit of the fractional-order system is designed and the experimental results match perfectly with the numerical simulations.
文摘NTRU is a lattice-based public key cryptosystem featuring reasonably short, easily created keys, high speed, and low memory requirements, seems viable for wireless network. This paper presents two optimized designs based on the enhanced NTRU algorithm. One is a light-weight and fast NTRU core, it performs encryption only. This work has a gate-count of 1175 gates and a power consumption of 1.51 μW. It can finish the whole encryption process in 1498 μs at 500 kHz. As such, it is perfect for wireless sensor network. Another high-speed NTRU core is capable of both encryption and decryption, with delays of 16,064 μs and 128,010 μs in encryption and decryption respectively. Moreover, it consists of 25,758 equivalent gates and has a total power consumption of 59.2 μW (it will be reduced greatly if low power methods were adopted). This core is recommended to be used in base stations or servers in wireless network.
文摘The paper is focused on available server management in Internet connected network environments. The local backup servers are hooked up by LAN and replace broken main server immediately and several different types of backup servers are also considered. The remote backup servers are hooked up by VPN (Virtual Private Network) with high-speed optical network. A Virtual Private Network (VPN) is a way to use a public network infrastructure and hooks up long-distance servers within a single network infrastructure. The remote backup servers also replace broken main severs immediately under the different conditions with local backups. When the system performs a mandatory routine maintenance of main and local backup servers, auxiliary servers from other location are being used for backups during idle periods. Analytically tractable results are obtained by using several mathematical techniques and the results are demonstrated in the framework of optimized networked server allocation problems. The operational workflow give the guidelines for the actual implementations.
文摘The advances of digital arithmetic techniques permit computer designers to implement high speed application specific chips. The currently produced digital circuits have demonstrated high performance in terms of several criteria, such as, high clock rate, short input/output delay, small silicon area, and low power dissipation. In this paper, we implement several sinusoidal generation methods to optimize their performance and output using advanced digital arithmetic techniques. In this paper, the implementations of advanced digital oscillator structures with and without pipelining are proposed. The synthesis results of the implementation with pipelining have proven that it is superior to other sinusoidal generation methods in terms of the maximum frequency and signal resolution. Hence, this method is used in the design of the proposed digital oscillator chip.
基金This work was supported by the Natural Science Foundation of Jiangsu Province under Grant BK20171458in part by the Natural Science Foundation of China under Grant Nos.61672290 and 61802002+2 种基金the Natural Science Foundation of Jiangsu Higher Education Institutions of China under Grant No.19KJB520028Jiangsu Graduate Scientific Research Innovation Program under Grant No.KYCX20_0978the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
文摘With the rapid development of quantum theory and technology in recent years,especially the emergence of some quantum cloud computing platforms,more and more researchers are not satisfied with the theoretical derivation and simulation verification of quantum computation(especially quantum algorithms),experimental verification on real quantum devices has become a new trend.In this paper,three representative quantum algorithms,namely Deutsch-Jozsa,Grover,and Shor algorithms,are briefly depicted,and then their implementation circuits are presented,respectively.We program these circuits on python with QISKit to connect the remote real quantum devices(i.e.,ibmqx4,ibmqx5)on IBM Q to verify these algorithms.The experimental results not only show the feasibility of these algorithms,but also serve to evaluate the functionality of these devices.
基金the Hi-Tech Research and Development Program of China (2006AA01Z226)the Scientific Research Foundation of Huazhong University of Science and Technology (2006Z001B)
文摘This article examines vulnerabilities to power analysis attacks between software and hardware implementations of cryptographic algorithms. Representative platforms including an Atmel 89S8252 8-bit processor and a 0.25 um 1.8 v standard cell circuit are proposed to implement the advance encryption standard （AES）. A simulation-based experimental environment is built to acquire power data, and single-bit differential power analysis （DPA）, and multi-bit DPA and correlation power analysis （CPA） attacks are conducted on two implementations respectively. The experimental results show that the hardware implementation has less data-dependent power leakages to resist power attacks. Furthermore, an improved DPA approach is proposed. It adopts hamming distance of intermediate results as power model and arranges plaintext inputs to differentiate power traces to the maximal probability. Compared with the original power attacks, our improved DPA performs a successful attack on AES hardware implementations with acceptable power measurements and fewer computations.
文摘Objective:This review aimed to identify the barriers and facilitators to equitable coronavirus disease 2019(COVID-19)vaccine distribution in Nigeria using the consolidated framework for implementation research(CFIR).Methods:A comprehensive search strategy was applied across five databases—Web of Science,MEDLINE,EMBASE,CAB Direct,and CINAHL.The search,conducted as part of a scoping review,yielded 2,751 citations.Seven studies met the inclusion criteria after screening.Data were extracted and analyzed using CFIR constructs to identify key barriers and facilitators to equitable vaccine distribution.Results:Six barriers were identified:limited physical and socioeconomic access,bribery,nepotism,and insufficient availability of translated information.Facilitators included community involvement as local monitoring agents,unannounced staff inspections,healthcare worker training tailored to community needs,and localized outreach strategies such as jingles and call-in programs.CFIR constructs,including Local Conditions,Tailoring Strategies,Available Resources,and Physical Infrastructure,provided a framework for analyzing the findings.Conclusion:This review highlights significant barriers and promising facilitators to equitable vaccine distribution in Nigeria.Targeted interventions,such as community engagement,anti-corruption measures,and culturally tailored strategies,are critical to addressing these challenges and improving access.These findings underscore the need for localized,equity-focused approaches to enhance vaccine distribution systems in Nigeria and other low-resource settings.
文摘The Royal Tropical Institute(KIT)in Amsterdam is an independent centre of knowledge and expertise in the areas of international and intercultural cooperation,operating at the interface between theory and practice and between policy and implementation.The Institute contributes to sustainable development,poverty alleviation and cultural preservation and exchange.
文摘Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds that the low-altitude economy can effectively promote the development of high-end and diversified tourism in Zhejiang by innovating tourism formats,optimizing resource allocation,and enhancing tourist experiences.Besides,it analyzes the current development status of the low-altitude economy in Zhejiang and its potential for integration with tourism,revealing specific enabling pathways for tourism transformation,including low-altitude sightseeing,aviation tourism,and low-altitude sports.Finally,it proposes policy recommendations such as strengthening policy support,enhancing infrastructure development,and cultivating market entities.The findings aim to provide theoretical references and practical guidance for the high-quality development of tourism in Zhejiang Province.
文摘Digital health is transforming healthcare by integrating advanced technologies to make healthcare more accessible,efficient,and personalized.From electronic health records,telemedicine,wearable devices,and artificial intelligence to the recent smart hospitals,digital health is improving patient care and outcomes while reducing healthcare costs.However,the integration of digital health faces several challenges,including data privacy,cybersecurity risks,and inequitable access to technology.This article provides an overview of the current state of digital health,key challenges in implementation,and potential solutions to maximize the benefits of digital health and ensure efficient,equitable,and patient‐centered healthcare in the future.
文摘The vonoprazan(VPZ)triple therapy regimen for Helicobacter pylori(H.pylori)eradication developed by Han et al employs a scientifically rigorous clinical trial design.This multicenter randomized controlled trial establishes a standardized treatment framework aimed at improving H.pylori eradication rates,focusing on simplifying treatment regimens,shortening therapy duration,and optimizing therapeutic outcomes.The core of clinical translation lies in improving drug accessibility,establishing multidimensional safety evaluation systems,and optimizing cost-effectiveness.Conducting regional adaptability studies and comprehensive safety assessments is crucial for enhancing VPZ regimen effectiveness in China’s diverse healthcare environments.This study provides important evidence-based support for optimizing H.pylori treatment strategies in China,though further validation of universal applicability for nationwide implementation remains necessary.
基金the 2023 Open Project of the Kazakhstan Research Center at YiIi Normal University,Study on National Language Education Policy in Kazakhstan Under the Belt and Road Initiative(No.2023HSKSTYJYB007).
文摘Language policies are of great significance to a nation’s stability,unity,and development.Uzbekistan’s language policies have reflected the political,economic,and cultural dynamics of different periods throughout historical changes,influencing social structures and ethnic relations.This paper summarizes the characteristics of Uzbekistan’s language policies in different eras:During the Tsarist Russian period,the Russification of language policies hindered the development of local languages;in the Soviet era,policies adopted a dual approach,promoting both Russian and prioritizing ethnic languages;after independence,Uzbekistan established Uzbek as the state language and emphasized foreign language education.The current language policy in Uzbekistan presents a complex landscape:While emphasizing the dominant role of the national language helps preserve its heritage,it may easily spark ethnic and political tensions;promoting pluralism and inclusivity brings benefits but faces challenges in balancing language statuses,resource allocation,management,and communication;modernization efforts encounter difficulties in standardizing dialects and foreign loanwords;and in international exchanges,there is a need to balance relations with global lingua francas.In conclusion,Uzbekistan’s language policies have undergone unique transformations and face numerous challenges.In-depth research is crucial for improving the country’s policies and enhancing China-Uzbekistan cooperation.Proactive measures are needed to address these challenges,ensuring the sustainability of language policies and fostering greater national prosperity.
基金Supported by Clinical Translational Medicine Project of the Department of Science and Technology of Anhui Province,No.202427b10020138.
文摘Kang et al published a study recently in the World Journal of Gastroenterology introducing an interpretable machine learning model to predict anastomotic leakage after rectal cancer surgery,highlighting postoperative serum calcium as a key predictive feature.While this represents a significant advancement,we argue that reliance on a static calcium threshold may limit clinical applicability.We advocate for a dynamic,trajectory-based assessment of serum calcium levels across perioperative time points,using modeling approaches such as time-series regression or mixed-effects models.Furthermore,the model’s robustness could be improved by incorporating systemic inflammation and nutritional indices such as C-reactive protein,procalcitonin,the neutrophil-to-lymphocyte ratio,and the systemic immune-inflammation index,supported by recent prospective studies.Finally,generalizability remains a concern,warranting broader validation and clearer clinical deployment strategies.By addressing these aspects,the model’s clinical translation and decision-making impact could be substantially enhanced.
基金supported in part by the National Natural Science Foundation of China(No.62162016)in part by the Innovation Project of Guangxi Graduate Education(Nos.YCBZ2023132 and YCSW2023304).
文摘The efficient implementation of the Advanced Encryption Standard(AES)is crucial for network data security.This paper presents novel hardware implementations of the AES S-box,a core component,using tower field representations and Boolean Satisfiability(SAT)solvers.Our research makes several significant contri-butions to the field.Firstly,we have optimized the GF(24)inversion,achieving a remarkable 31.35%area reduction(15.33 GE)compared to the best known implementations.Secondly,we have enhanced multiplication implementa-tions for transformation matrices using a SAT-method based on local solutions.This approach has yielded notable improvements,such as a 22.22%reduction in area(42.00 GE)for the top transformation matrix in GF((24)2)-type S-box implementation.Furthermore,we have proposed new implementations of GF(((22)2)2)-type and GF((24)2)-type S-boxes,with the GF(((22)2)2)-type demonstrating superior performance.This implementation offers two variants:a small area variant that sets new area records,and a fast variant that establishes new benchmarks in Area-Execution-Time(AET)and energy consumption.Our approach significantly improves upon existing S-box implementations,offering advancements in area,speed,and energy consumption.These optimizations contribute to more efficient and secure AES implementations,potentially enhancing various cryptographic applications in the field of network security.
文摘Early childhood character education is a critical element in shaping an individual’s moral foundation and fostering a sense of social responsibility.It plays a fundamental role in overall personal development.Although China’s early childhood character education has made progress with the support of policies and practical exploration,it still faces challenges such as the homogenization of educational models,a formalization of home-kindergarten cooperation,a single-dimensional evaluation system,and a need for further improvement in teachers’professional competence in character education.This paper draws on core theories of character education(e.g.,social learning theory and cognitive moral development theory)and incorporates representative case studies to conduct an in-depth analysis of the current landscape and associated challenges.It proposes innovative approaches,which include establishing a“threefold”system of implementation,enhancing the mechanisms for home-kindergarten co-education,optimizing and ensuring a multidimensional and dynamic evaluation system,equitably allocating teaching resources,and expanding the social support networks.The aim is to offer theoretical reference and practical solutions to promote the scientific and systematic development of early childhood character education.
基金supported by the China Scholarship Council(CSC)(Grant No.202006060033).
文摘Both the complex geometrical morphology of rough-walled rock fractures and the nonlinearity of fluid flow contribute to resistance in fluid flow through rock fractures.The interactions of the shear-flow process further complicate the characterisation of flow behaviours in rock fractures.In this study,an improved friction factor model involving both the effects of viscous and inertial forces is presented based on the Forchheimer equation.The model incorporates two key variables,i.e.Reynolds number and relative roughness,which reflect the effects of flow regimes and fracture roughness,respectively.The changes in geometrical parameters induced by shearing are considered,with the peak asperity height predicted through a correlation with post-peak roughness degradation.The hydraulic aperture during shearing is estimated using a suggested equation that accounts for the mobilised contact area ratio and variable aperture distribution.The parametric sensitivity analysis reveals that shear-induced changes in fracture geometry enhance the flow nonlinearity in rock fractures.The model performs well in predicting the friction factor based on two validation criteria.Then,the proposed friction factor model is incorporated into the three-dimensional distinct element code(3DEC)in the form of the Darcy-Weisbach equation.Coupled with the numerically implemented mechanical model and hydraulic aperture prediction model,numerical simulations of coupled shear-flow processes in single rock fractures are conducted.The simulation outcomes are validated through comparison with the experimental results,showing acceptable agreement and demonstrating that the numerical model is capable of accurately evaluating the hydro-mechanical coupling behaviour during the shearing of rock fractures.
文摘As an emerging technological form,the metaverse provides innovative transformations for all levels of education-including scenarios,resources,and models-through its highly immersive and powerful social interaction characteristics.Educational evaluation is core to assessing teaching effects and improving teaching strategies.With the technical support of the metaverse,challenges in traditional educational evaluation can be addressed,and comprehensive multi-dimensional portraits of individuals and collectives can be depicted,effectively enhancing teaching outcomes.Therefore,it has important value and untapped potential.This paper first analyzes the characteristics of educational evaluation in the metaverse context,discusses possible opportunities and challenges,then explores comprehensive practical paths from macro,meso,and micro levels,providing suggestions for the reform of educational evaluation in the metaverse environment.
基金Mechanism of Nanotechnology-driven Polyphyllin I in Sensitizing PD-1 Monoclonal Antibody in Breast Cancer(82204922)Nanotechnology-driven Polyphyllin I Affects Mitochondrial Homeostasis via Cuproptosis and Its Mechanism in Breast Cancer Treatment(ZZ18-YQ-022)。
文摘Oncology covers a wide range of knowledge and is more difficult compared to other clinical disciplines.Therefore,it is crucial to seek an efficient teaching method for oncology education.In recent years,China’s internet technology has achieved rapid development.Massive Open Online Course(MOOC),a blended learning approach based on internet technology,has strong applicability to medical education.It can not only improve teaching quality but also promote further reform of the discipline.Based on this,our study searched for relevant research at home and abroad and reviewed the implementation path of integrating MOOC and blended learning in oncology education.This provides a theoretical foundation for the innovation of oncology teaching models,improves the level of oncology teaching,and lays a solid foundation for talent reserves in oncology departments.
文摘In the wave of higher education internationalization,college students’career education is faced with problems such as inadequate integration of international elements in teaching content,insufficient depth of international cooperation in practical links,lack of international professional experience among the teaching staff,and insufficient emphasis on the cultivation of multicultural adaptability in the education model.Based on this,this paper deeply explores the new requirements put forward by internationalization for college students’career education and its diversified implementation paths from the perspective of higher education internationalization.It aims to build a comprehensive and multi-level career education system and improve students’international competitiveness through strategies such as constructing an internationalized curriculum system,expanding international cooperation practice projects,strengthening international exchanges and training for teachers,and integrating multicultural education.
文摘Background:Community-based first responders face high levels of workplace stressors that can pro-foundly impact their physical and mental health.Mindfulness-based interventions have shown promise in decreasing stress and increasing psychological resilience;however,implementation is difficult due to unpredictability of the job,department culture,and generational preferences.The objective of this qualitative study was to identify and enhance understanding of the specific needs and potential barriers and facilitators for the implementation of mindfulness-based programming for community-based first responders.Methods:A phenomenological qualitative study design was used to gain insights into the lived experiences of first responders and elicit perceptions regarding barriers and facilitators for engaging in mindfulness activities.During virtual semi-structured interviews,eleven career firefighters and emergency medical service(EMS)providers offered feedback relative to worksite mindfulness practices,and the use of a stress reduction smartphone application.The Consolidated Framework for Implementation Research was used to guide the analysis relative to barriers and facilitators of implementation success and sustainability.Results:First responders expressed openness to mindfulness-based interventions and a smartphone app that would provide stress reduction content,however,they were adamant that programming needed to be accessible and easily integrated into their workday.They also reinforced that organizational culture and leadership support for their health and well-being were overarching factors essential for implementation success.Conclusions:First responders were supportive of evidence-based mindfulness practices,optimally developed and/or facilitated by someone with intimate knowledge of their unique work environments and challenges.Organizational culture and leadership support were essential for implementation success and sustainability.
