Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often stru...Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often struggle with low-contrast MRI images,class imbalance,and suboptimal feature extraction.This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans.Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization(CLAHE)and Enhanced Super-Resolution Generative Adversarial Networks(ESRGAN).A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient(MCC)-based evaluation method into the design.The trained and validated model gives a 98.88%accuracy rate and 0.9614 MCC score.We also performed a 10-fold cross-validation experiment with an average accuracy of 96.52%(±1.51),a loss of 0.1671,and an MCC score of 0.9429 across folds.The proposed framework outperforms the state-of-the-art models with a 98%weighted F1-score while decreasing misdiagnosis results for every AD stage.The model demonstrates apparent separation abilities between AD progression stages according to the results of the confusion matrix analysis.These results validate the effectiveness of hybrid DL models with adaptive preprocessing for early and reliable Alzheimer’s diagnosis,contributing to improved computer-aided diagnosis(CAD)systems in clinical practice.展开更多
The rapid development of brain-like neural networks and secure data transmission technologies has placed greater demands on highly complex neural network systems and highly secure encryption methods.To this end,the pa...The rapid development of brain-like neural networks and secure data transmission technologies has placed greater demands on highly complex neural network systems and highly secure encryption methods.To this end,the paper proposes a novel high-dimensional memristor synapse-coupled hyperchaotic neural network by using the designed memristor as the synapse to connect an inertial neuron(IN)and a Hopfield neural network(HNN).By using numerical tools including bifurcation plots,phase plots,and basins of attraction,it is found that the dynamics of this system are closely related to the memristor coupling strength,self-connection synaptic weights,and inter-connection synaptic weights,and it can exhibit excellent hyperchaotic behaviors and coexisting multi-stable patterns.Through PSIM circuit simulations,the complex dynamics of the coupled IN-HNN system are verified.Furthermore,a DNA-encoded encryption algorithm is given,which utilizes generated hyperchaotic sequences to achieve encoding,operation,and decoding of DNA.The results show that this algorithm possesses strong robustness against statistical attacks,differential attacks,and noise interference,and can effectively resist known/selected plaintext attacks.This work will provide new ideas for the modeling of large-scale brainlike neural networks and high-security image encryption.展开更多
Recent studies indicate that millions of individuals suffer from renal diseases,with renal carcinoma,a type of kidney cancer,emerging as both a chronic illness and a significant cause of mortality.Magnetic Resonance I...Recent studies indicate that millions of individuals suffer from renal diseases,with renal carcinoma,a type of kidney cancer,emerging as both a chronic illness and a significant cause of mortality.Magnetic Resonance Imaging(MRI)and Computed Tomography(CT)have become essential tools for diagnosing and assessing kidney disorders.However,accurate analysis of thesemedical images is critical for detecting and evaluating tumor severity.This study introduces an integrated hybrid framework that combines three complementary deep learning models for kidney tumor segmentation from MRI images.The proposed framework fuses a customized U-Net and Mask R-CNN using a weighted scheme to achieve semantic and instance-level segmentation.The fused outputs are further refined through edge detection using Stochastic FeatureMapping Neural Networks(SFMNN),while volumetric consistency is ensured through Improved Mini-Batch K-Means(IMBKM)clustering integrated with an Encoder-Decoder Convolutional Neural Network(EDCNN).The outputs of these three stages are combined through a weighted fusion mechanism,with optimal weights determined empirically.Experiments on MRI scans from the TCGA-KIRC dataset demonstrate that the proposed hybrid framework significantly outperforms standalone models,achieving a Dice Score of 92.5%,an IoU of 87.8%,a Precision of 93.1%,a Recall of 90.8%,and a Hausdorff Distance of 2.8 mm.These findings validate that the weighted integration of complementary architectures effectively overcomes key limitations in kidney tumor segmentation,leading to improved diagnostic accuracy and robustness in medical image analysis.展开更多
基金funded by the Deanship of Graduate Studies and Scientific Research at Jouf University under grant No.(DGSSR-2025-02-01295).
文摘Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often struggle with low-contrast MRI images,class imbalance,and suboptimal feature extraction.This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans.Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization(CLAHE)and Enhanced Super-Resolution Generative Adversarial Networks(ESRGAN).A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient(MCC)-based evaluation method into the design.The trained and validated model gives a 98.88%accuracy rate and 0.9614 MCC score.We also performed a 10-fold cross-validation experiment with an average accuracy of 96.52%(±1.51),a loss of 0.1671,and an MCC score of 0.9429 across folds.The proposed framework outperforms the state-of-the-art models with a 98%weighted F1-score while decreasing misdiagnosis results for every AD stage.The model demonstrates apparent separation abilities between AD progression stages according to the results of the confusion matrix analysis.These results validate the effectiveness of hybrid DL models with adaptive preprocessing for early and reliable Alzheimer’s diagnosis,contributing to improved computer-aided diagnosis(CAD)systems in clinical practice.
基金Project supported by the Training Plan of Young Backbone Teachers in Universities of Henan Province(Grant No.2023GGJS142)the Key Scientific Research of Colleges and Universities in Henan Province,China(Grant No.25A120009)+1 种基金Changzhou Leading Innovative Talent Introduction and Cultivation Project(Grant No.CQ20240102)Changzhou Applied Basic Research Program(Grant No.CJ20253065)。
文摘The rapid development of brain-like neural networks and secure data transmission technologies has placed greater demands on highly complex neural network systems and highly secure encryption methods.To this end,the paper proposes a novel high-dimensional memristor synapse-coupled hyperchaotic neural network by using the designed memristor as the synapse to connect an inertial neuron(IN)and a Hopfield neural network(HNN).By using numerical tools including bifurcation plots,phase plots,and basins of attraction,it is found that the dynamics of this system are closely related to the memristor coupling strength,self-connection synaptic weights,and inter-connection synaptic weights,and it can exhibit excellent hyperchaotic behaviors and coexisting multi-stable patterns.Through PSIM circuit simulations,the complex dynamics of the coupled IN-HNN system are verified.Furthermore,a DNA-encoded encryption algorithm is given,which utilizes generated hyperchaotic sequences to achieve encoding,operation,and decoding of DNA.The results show that this algorithm possesses strong robustness against statistical attacks,differential attacks,and noise interference,and can effectively resist known/selected plaintext attacks.This work will provide new ideas for the modeling of large-scale brainlike neural networks and high-security image encryption.
基金funded by the Ongoing Research Funding Program-Research Chairs(ORF-RC-2025-2400),King Saud University,Riyadh,Saudi Arabia。
文摘Recent studies indicate that millions of individuals suffer from renal diseases,with renal carcinoma,a type of kidney cancer,emerging as both a chronic illness and a significant cause of mortality.Magnetic Resonance Imaging(MRI)and Computed Tomography(CT)have become essential tools for diagnosing and assessing kidney disorders.However,accurate analysis of thesemedical images is critical for detecting and evaluating tumor severity.This study introduces an integrated hybrid framework that combines three complementary deep learning models for kidney tumor segmentation from MRI images.The proposed framework fuses a customized U-Net and Mask R-CNN using a weighted scheme to achieve semantic and instance-level segmentation.The fused outputs are further refined through edge detection using Stochastic FeatureMapping Neural Networks(SFMNN),while volumetric consistency is ensured through Improved Mini-Batch K-Means(IMBKM)clustering integrated with an Encoder-Decoder Convolutional Neural Network(EDCNN).The outputs of these three stages are combined through a weighted fusion mechanism,with optimal weights determined empirically.Experiments on MRI scans from the TCGA-KIRC dataset demonstrate that the proposed hybrid framework significantly outperforms standalone models,achieving a Dice Score of 92.5%,an IoU of 87.8%,a Precision of 93.1%,a Recall of 90.8%,and a Hausdorff Distance of 2.8 mm.These findings validate that the weighted integration of complementary architectures effectively overcomes key limitations in kidney tumor segmentation,leading to improved diagnostic accuracy and robustness in medical image analysis.
