Organoids possess immense potential for unraveling the intricate functions of human tissues and facilitating preclinical disease treatment.Their applications span from high-throughput drug screening to the modeling of...Organoids possess immense potential for unraveling the intricate functions of human tissues and facilitating preclinical disease treatment.Their applications span from high-throughput drug screening to the modeling of complex diseases,with some even achieving clinical translation.Changes in the overall size,shape,boundary,and other morphological features of organoids provide a noninvasive method for assessing organoid drug sensitivity.However,the precise segmentation of organoids in bright-field microscopy images is made difficult by the complexity of the organoid morphology and interference,including overlapping organoids,bubbles,dust particles,and cell fragments.This paper introduces the precision organoid segmentation technique(POST),which is a deep-learning algorithm for segmenting challenging organoids under simple bright-field imaging conditions.Unlike existing methods,POST accurately segments each organoid and eliminates various artifacts encountered during organoid culturing and imaging.Furthermore,it is sensitive to and aligns with measurements of organoid activity in drug sensitivity experiments.POST is expected to be a valuable tool for drug screening using organoids owing to its capability of automatically and rapidly eliminating interfering substances and thereby streamlining the organoid analysis and drug screening process.展开更多
Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bac...Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions.展开更多
The rising need for precision farming and sustainable land management has catalyzed the requirement for sophisticated means of deriving practical data from remote sensing images.Image segmentation,or the process of di...The rising need for precision farming and sustainable land management has catalyzed the requirement for sophisticated means of deriving practical data from remote sensing images.Image segmentation,or the process of dividing the image into semantically relevant parts,has become a groundbreaking technology that allows resolving the problem of transitioning the pixel-level data to a parcel-level analysis.This review is a synthesis of the segmentation methods and their use in crop research and geospatial science.The architectures of pixel-based,object-based,and deep learning(convolutional neural networks,U-Net,Mask R-CNN,and Transformer models)are considered in terms of principles,capabilities,and limitations.Multi-spectral,hyperspectral,LiDAR,and SAR data are integrated to improve the efficiency of segmentation,allowing the possible delineation of fields,the classification of crops,health monitoring,monitoring of yields,and stress identification.In addition to agriculture,segmentation helps in land use and land cover mapping,identification of temporal change,monitoring of the environment,and is used in combination with GIS-based spatial modeling.Nevertheless,issues related to data heterogeneity,mixed pixels,computational requirements,and inadequate availability of labelled data still exist despite the major progress.The future directions involve multi-source data fusion,pixel-to-parcel pipeline automation,and predictive models based on AI,which are used to enhance its scalability,robustness,and the ability to monitor in real-time.This review makes it clear that the use of image segmentation as a tool in generating precision agriculture,sustainable land use,and informed geospatial.展开更多
Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual infor...Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual information.Although the subsequent U-KAN model enhances nonlinear representation capabilities,it still faces challenges such as gradient vanishing during deep network training and spatial detail loss during feature downsampling,resulting in insufficient segmentation accuracy for edge structures and minute lesions.To address these challenges,this paper proposes the RE-UKAN model,which innovatively improves upon U-KAN.Firstly,a residual network is introduced into the encoder to effectively mitigate gradient vanishing through cross-layer identity mappings,thus enhancing modelling capabilities for complex pathological structures.Secondly,Efficient Local Attention(ELA)is integrated to suppress spatial detail loss during downsampling,thereby improving the perception of edge structures and minute lesions.Experimental results on four public datasets demonstrate that RE-UKAN outperforms existing medical image segmentation methods across multiple evaluation metrics,with particularly outstanding performance on the TN-SCUI 2020 dataset,achieving IoU of 88.18%and Dice of 93.57%.Compared to the baseline model,it achieves improvements of 3.05%and 1.72%,respectively.These results fully demonstrate RE-UKAN’s superior detail retention capability and boundary recognition accuracy in complex medical image segmentation tasks,providing a reliable solution for clinical precision segmentation.展开更多
Satellite image segmentation plays a crucial role in remote sensing,supporting applications such as environmental monitoring,land use analysis,and disaster management.However,traditional segmentation methods often rel...Satellite image segmentation plays a crucial role in remote sensing,supporting applications such as environmental monitoring,land use analysis,and disaster management.However,traditional segmentation methods often rely on large amounts of labeled data,which are costly and time-consuming to obtain,especially in largescale or dynamic environments.To address this challenge,we propose the Semi-Supervised Multi-View Picture Fuzzy Clustering(SS-MPFC)algorithm,which improves segmentation accuracy and robustness,particularly in complex and uncertain remote sensing scenarios.SS-MPFC unifies three paradigms:semi-supervised learning,multi-view clustering,and picture fuzzy set theory.This integration allows the model to effectively utilize a small number of labeled samples,fuse complementary information from multiple data views,and handle the ambiguity and uncertainty inherent in satellite imagery.We design a novel objective function that jointly incorporates picture fuzzy membership functions across multiple views of the data,and embeds pairwise semi-supervised constraints(must-link and cannot-link)directly into the clustering process to enhance segmentation accuracy.Experiments conducted on several benchmark satellite datasets demonstrate that SS-MPFC significantly outperforms existing state-of-the-art methods in segmentation accuracy,noise robustness,and semantic interpretability.On the Augsburg dataset,SS-MPFC achieves a Purity of 0.8158 and an Accuracy of 0.6860,highlighting its outstanding robustness and efficiency.These results demonstrate that SSMPFC offers a scalable and effective solution for real-world satellite-based monitoring systems,particularly in scenarios where rapid annotation is infeasible,such as wildfire tracking,agricultural monitoring,and dynamic urban mapping.展开更多
This article studies the problem of image segmentation-based semantic communication in autonomous driving.In real traffic scenes,the detecting of objects(e.g.,vehicles and pedestrians)is more important to guarantee dr...This article studies the problem of image segmentation-based semantic communication in autonomous driving.In real traffic scenes,the detecting of objects(e.g.,vehicles and pedestrians)is more important to guarantee driving safety,which is always ignored in existing works.Therefore,we propose a vehicular image segmentation-oriented semantic communication system,termed VIS-SemCom,focusing on transmitting and recovering image semantic features of high-important objects to reduce transmission redundancy.First,we develop a semantic codec based on Swin Transformer architecture,which expands the perceptual field thus improving the segmentation accuracy.To highlight the important objects'accuracy,we propose a multi-scale semantic extraction method by assigning the number of Swin Transformer blocks for diverse resolution semantic features.Also,an importance-aware loss incorporating important levels is devised,and an online hard example mining(OHEM)strategy is proposed to handle small sample issues in the dataset.Finally,experimental results demonstrate that the proposed VIS-SemCom can achieve a significant mean intersection over union(mIoU)performance in the SNR regions,a reduction of transmitted data volume by about 60%at 60%mIoU,and improve the segmentation accuracy of important objects,compared to baseline image communication.展开更多
Multilevel image segmentation is a critical task in image analysis,which imposes high requirements on the global search capability and convergence efficiency of segmentation algorithms.In this paper,an improved Artifi...Multilevel image segmentation is a critical task in image analysis,which imposes high requirements on the global search capability and convergence efficiency of segmentation algorithms.In this paper,an improved Artificial Protozoa Optimization algorithm,termed the two-stage Taguchi-assisted Gaussian–Levy Artificial Protozoa Optimization(TGAPO)algorithm,is proposed and applied tomultilevel image segmentation.The proposed algorithm adopts a two-stage evolutionary mechanism.In the first stage,Gaussian perturbation is introduced to enhance local search capability;in the second stage,Levy flight is incorporated to expand the global search range;and finally,the Taguchi strategy is employed to further refine the optimal solution.Consequently,the global optimization performance and robustness of the algorithm are significantly improved.To evaluate the effectiveness of the proposed TGAPO algorithm,comparative experiments are conducted with representative optimization algorithms,including the Grey Wolf Optimizer(GWO)and Particle Swarm Optimization(PSO),in the context ofmultilevel image segmentation.The segmentation quality is assessed using the minimum cross-entropy function as the performance metric.Experimental results demonstrate that the TGAPO algorithm outperforms the comparison algorithms in terms of segmentation accuracy and convergence speed,and exhibits superior stability in high-threshold segmentation tasks.Furthermore,the proposedmethod achieves excellentmulti-threshold segmentation performance for color images and shows strong potential for practical applications.展开更多
Automatic and accurate medical image segmentation remains a fundamental task in computer-aided diagnosis and treatment planning.Recent advances in foundation models,such as the medical-focused Segment AnythingModel(Me...Automatic and accurate medical image segmentation remains a fundamental task in computer-aided diagnosis and treatment planning.Recent advances in foundation models,such as the medical-focused Segment AnythingModel(MedSAM),have demonstrated strong performance but face challenges inmanymedical applications due to anatomical complexity and a limited domain-specific prompt.Thiswork introduces amethodology that enhances segmentation robustness and precision by automatically generating multiple informative point prompts,rather than relying on single inputs.The proposed approach randomly samples sets of spatially distributed point prompts based on image features,enabling MedSAM to better capture fine-grained anatomical structures and boundaries.During inference,probability maps are aggregated to reduce local misclassifications without additional model training.Extensive experiments on various computed tomography(CT)and magnetic resonance imaging(MRI)datasets demonstrate improvements in Dice Similarity Coefficient(DSC)and Normalized Surface Dice(NSD)metrics compared to baseline SAM and Scribble Prompt models.A semi-automatic point sampling version based on the ground truth segmentations yielded enhanced results,achieving up to 92.1%DSC and 86.6%NSD,with significant gains in delineating complex organs such as the pancreas,colon,kidney,and brain tumours.The main novelty of our method consists of effectively combining the results of multiple point prompts into the medical segmentation pipeline so that single-point prompt methods are outperformed.Overall,the proposed model offers a straightforward yet effective approach to improve medical image segmentation performance while maintaining computational efficiency.展开更多
Background:Diabetic macular edema is a prevalent retinal condition and a leading cause of visual impairment among diabetic patients’Early detection of affected areas is beneficial for effective diagnosis and treatmen...Background:Diabetic macular edema is a prevalent retinal condition and a leading cause of visual impairment among diabetic patients’Early detection of affected areas is beneficial for effective diagnosis and treatment.Traditionally,diagnosis relies on optical coherence tomography imaging technology interpreted by ophthalmologists.However,this manual image interpretation is often slow and subjective.Therefore,developing automated segmentation for macular edema images is essential to enhance to improve the diagnosis efficiency and accuracy.Methods:In order to improve clinical diagnostic efficiency and accuracy,we proposed a SegNet network structure integrated with a convolutional block attention module(CBAM).This network introduces a multi-scale input module,the CBAM attention mechanism,and jump connection.The multi-scale input module enhances the network’s perceptual capabilities,while the lightweight CBAM effectively fuses relevant features across channels and spatial dimensions,allowing for better learning of varying information levels.Results:Experimental results demonstrate that the proposed network achieves an IoU of 80.127%and an accuracy of 99.162%.Compared to the traditional segmentation network,this model has fewer parameters,faster training and testing speed,and superior performance on semantic segmentation tasks,indicating its highly practical applicability.Conclusion:The C-SegNet proposed in this study enables accurate segmentation of Diabetic macular edema lesion images,which facilitates quicker diagnosis for healthcare professionals.展开更多
Image segmentation is attracting increasing attention in the field of medical image analysis.Since widespread utilization across various medical applications,ensuring and improving segmentation accuracy has become a c...Image segmentation is attracting increasing attention in the field of medical image analysis.Since widespread utilization across various medical applications,ensuring and improving segmentation accuracy has become a crucial topic of research.With advances in deep learning,researchers have developed numerous methods that combine Transformers and convolutional neural networks(CNNs)to create highly accurate models for medical image segmentation.However,efforts to further enhance accuracy by developing larger and more complex models or training with more extensive datasets,significantly increase computational resource consumption.To address this problem,we propose BiCLIP-nnFormer(the prefix"Bi"refers to the use of two distinct CLIP models),a virtual multimodal instrument that leverages CLIP models to enhance the segmentation performance of a medical segmentation model nnFormer.Since two CLIP models(PMC-CLIP and CoCa-CLIP)are pre-trained on large datasets,they do not require additional training,thus conserving computation resources.These models are used offline to extract image and text embeddings from medical images.These embeddings are then processed by the proposed 3D CLIP adapter,which adapts the CLIP knowledge for segmentation tasks by fine-tuning.Finally,the adapted embeddings are fused with feature maps extracted from the nnFormer encoder for generating predicted masks.This process enriches the representation capabilities of the feature maps by integrating global multimodal information,leading to more precise segmentation predictions.We demonstrate the superiority of BiCLIP-nnFormer and the effectiveness of using CLIP models to enhance nnFormer through experiments on two public datasets,namely the Synapse multi-organ segmentation dataset(Synapse)and the Automatic Cardiac Diagnosis Challenge dataset(ACDC),as well as a self-annotated lung multi-category segmentation dataset(LMCS).展开更多
Potential high-temperature risks exist in heat-prone components of electric moped charging devices,such as sockets,interfaces,and controllers.Traditional detection methods have limitations in terms of real-time perfor...Potential high-temperature risks exist in heat-prone components of electric moped charging devices,such as sockets,interfaces,and controllers.Traditional detection methods have limitations in terms of real-time performance and monitoring scope.To address this,a temperature detection method based on infrared image processing has been proposed:utilizing the median filtering algorithm to denoise the original infrared image,then applying an image segmentation algorithm to divide the image.展开更多
The visual noise of each light intensity area is different when the image is drawn by Monte Carlo method.However,the existing denoising algorithms have limited denoising performance under complex lighting conditions a...The visual noise of each light intensity area is different when the image is drawn by Monte Carlo method.However,the existing denoising algorithms have limited denoising performance under complex lighting conditions and are easy to lose detailed information.So we propose a rendered image denoising method with filtering guided by lighting information.First,we design an image segmentation algorithm based on lighting information to segment the image into different illumination areas.Then,we establish the parameter prediction model guided by lighting information for filtering(PGLF)to predict the filtering parameters of different illumination areas.For different illumination areas,we use these filtering parameters to construct area filters,and the filters are guided by the lighting information to perform sub-area filtering.Finally,the filtering results are fused with auxiliary features to output denoised images for improving the overall denoising effect of the image.Under the physically based rendering tool(PBRT)scene and Tungsten dataset,the experimental results show that compared with other guided filtering denoising methods,our method improves the peak signal-to-noise ratio(PSNR)metrics by 4.2164 dB on average and the structural similarity index(SSIM)metrics by 7.8%on average.This shows that our method can better reduce the noise in complex lighting scenesand improvethe imagequality.展开更多
Data augmentation plays an important role in training deep neural model by expanding the size and diversity of the dataset.Initially,data augmentation mainly involved some simple transformations of images.Later,in ord...Data augmentation plays an important role in training deep neural model by expanding the size and diversity of the dataset.Initially,data augmentation mainly involved some simple transformations of images.Later,in order to increase the diversity and complexity of data,more advanced methods appeared and evolved to sophisticated generative models.However,these methods required a mass of computation of training or searching.In this paper,a novel training-free method that utilises the Pre-Trained Segment Anything Model(SAM)model as a data augmentation tool(PTSAM-DA)is proposed to generate the augmented annotations for images.Without the need for training,it obtains prompt boxes from the original annotations and then feeds the boxes to the pre-trained SAM to generate diverse and improved annotations.In this way,annotations are augmented more ingenious than simple manipulations without incurring huge computation for training a data augmentation model.Multiple comparative experiments on three datasets are conducted,including an in-house dataset,ADE20K and COCO2017.On this in-house dataset,namely Agricultural Plot Segmentation Dataset,maximum improvements of 3.77%and 8.92%are gained in two mainstream metrics,mIoU and mAcc,respectively.Consequently,large vision models like SAM are proven to be promising not only in image segmentation but also in data augmentation.展开更多
Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to ...Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to the inability to effectively capture global information from images,CNNs can easily lead to loss of contours and textures in segmentation results.Notice that the transformer model can effectively capture the properties of long-range dependencies in the image,and furthermore,combining the CNN and the transformer can effectively extract local details and global contextual features of the image.Motivated by this,we propose a multi-branch and multi-scale attention network(M2ANet)for medical image segmentation,whose architecture consists of three components.Specifically,in the first component,we construct an adaptive multi-branch patch module for parallel extraction of image features to reduce information loss caused by downsampling.In the second component,we apply residual block to the well-known convolutional block attention module to enhance the network’s ability to recognize important features of images and alleviate the phenomenon of gradient vanishing.In the third component,we design a multi-scale feature fusion module,in which we adopt adaptive average pooling and position encoding to enhance contextual features,and then multi-head attention is introduced to further enrich feature representation.Finally,we validate the effectiveness and feasibility of the proposed M2ANet method through comparative experiments on four benchmark medical image segmentation datasets,particularly in the context of preserving contours and textures.展开更多
Convolutional neural network(CNN)with the encoder-decoder structure is popular in medical image segmentation due to its excellent local feature extraction ability but it faces limitations in capturing the global featu...Convolutional neural network(CNN)with the encoder-decoder structure is popular in medical image segmentation due to its excellent local feature extraction ability but it faces limitations in capturing the global feature.The transformer can extract the global information well but adapting it to small medical datasets is challenging and its computational complexity can be heavy.In this work,a serial and parallel network is proposed for the accurate 3D medical image segmentation by combining CNN and transformer and promoting feature interactions across various semantic levels.The core components of the proposed method include the cross window self-attention based transformer(CWST)and multi-scale local enhanced(MLE)modules.The CWST module enhances the global context understanding by partitioning 3D images into non-overlapping windows and calculating sparse global attention between windows.The MLE module selectively fuses features by computing the voxel attention between different branch features,and uses convolution to strengthen the dense local information.The experiments on the prostate,atrium,and pancreas MR/CT image datasets consistently demonstrate the advantage of the proposed method over six popular segmentation models in both qualitative evaluation and quantitative indexes such as dice similarity coefficient,Intersection over Union,95%Hausdorff distance and average symmetric surface distance.展开更多
Existing semi-supervisedmedical image segmentation algorithms use copy-paste data augmentation to correct the labeled-unlabeled data distribution mismatch.However,current copy-paste methods have three limitations:(1)t...Existing semi-supervisedmedical image segmentation algorithms use copy-paste data augmentation to correct the labeled-unlabeled data distribution mismatch.However,current copy-paste methods have three limitations:(1)training the model solely with copy-paste mixed pictures from labeled and unlabeled input loses a lot of labeled information;(2)low-quality pseudo-labels can cause confirmation bias in pseudo-supervised learning on unlabeled data;(3)the segmentation performance in low-contrast and local regions is less than optimal.We design a Stochastic Augmentation-Based Dual-Teaching Auxiliary Training Strategy(SADT),which enhances feature diversity and learns high-quality features to overcome these problems.To be more precise,SADT trains the Student Network by using pseudo-label-based training from Teacher Network 1 and supervised learning with labeled data,which prevents the loss of rare labeled data.We introduce a bi-directional copy-pastemask with progressive high-entropy filtering to reduce data distribution disparities and mitigate confirmation bias in pseudo-supervision.For the mixed images,Deep-Shallow Spatial Contrastive Learning(DSSCL)is proposed in the feature spaces of Teacher Network 2 and the Student Network to improve the segmentation capabilities in low-contrast and local areas.In this procedure,the features retrieved by the Student Network are subjected to a random feature perturbation technique.On two openly available datasets,extensive trials show that our proposed SADT performs much better than the state-ofthe-art semi-supervised medical segmentation techniques.Using only 10%of the labeled data for training,SADT was able to acquire a Dice score of 90.10%on the ACDC(Automatic Cardiac Diagnosis Challenge)dataset.展开更多
Lung cancer(LC)is a major cancer which accounts for higher mortality rates worldwide.Doctors utilise many imaging modalities for identifying lung tumours and their severity in earlier stages.Nowadays,machine learning(...Lung cancer(LC)is a major cancer which accounts for higher mortality rates worldwide.Doctors utilise many imaging modalities for identifying lung tumours and their severity in earlier stages.Nowadays,machine learning(ML)and deep learning(DL)methodologies are utilised for the robust detection and prediction of lung tumours.Recently,multi modal imaging emerged as a robust technique for lung tumour detection by combining various imaging features.To cope with that,we propose a novel multi modal imaging technique named versatile scale malleable image integration and patch wise attention network(VSMI2−PANet)which adopts three imaging modalities named computed tomography(CT),magnetic resonance imaging(MRI)and single photon emission computed tomography(SPECT).The designed model accepts input from CT and MRI images and passes it to the VSMI2 module that is composed of three sub-modules named image cropping module,scale malleable convolution layer(SMCL)and PANet module.CT and MRI images are subjected to image cropping module in a parallel manner to crop the meaningful image patches and provide them to the SMCL module.The SMCL module is composed of adaptive convolutional layers that investigate those patches in a parallel manner by preserving the spatial information.The output from the SMCL is then fused and provided to the PANet module.The PANet module examines the fused patches by analysing its height,width and channels of the image patch.As a result,it provides an output as high-resolution spatial attention maps indicating the location of suspicious tumours.The high-resolution spatial attention maps are then provided as an input to the backbone module which uses light wave transformer(LWT)for segmenting the lung tumours into three classes,such as normal,benign and malignant.In addition,the LWT also accepts SPECT image as input for capturing the variations precisely to segment the lung tumours.The performance of the proposed model is validated using several performance metrics,such as accuracy,precision,recall,F1-score and AUC curve,and the results show that the proposed work outperforms the existing approaches.展开更多
Background:Source-free unsupervised domain adaptation(SFUDA)methods aim to address the challenge of domain shift while preserving data privacy.Existing SFUDA approaches construct reliable and confident pseudo-labels f...Background:Source-free unsupervised domain adaptation(SFUDA)methods aim to address the challenge of domain shift while preserving data privacy.Existing SFUDA approaches construct reliable and confident pseudo-labels for target-domain data through denoising methods,thereby guiding the training of the target-domain model.The effectiveness of denoising approaches is influenced by the degree of domain gap between the source and target domains.A marked shift can cause the pseudo-labels to be unreliable,even after applying denoising.Methods:We propose a novel 2-stage framework for SFUDA called visual prompt source-free domain adaptation(VP-SFDA).We propose input-specific visual prompt in the first stage,prompting process,which bridges the target-domain data to source-domain distribution.Our method utilizes visual prompts and batch normalization constraint to enable the alignment model to learn domainspecific knowledge and align the target-domain data with the source-domain contribution.The second stage is the adaptation process,which aims at optimizing the segmentation model from the source domain to the target domain.This is accomplished through the denoising techniques,ultimately enhancing the performance.Results:Our study presents a comparative analysis of several SFUDA techniques in the VPSFDA framework across 4 tasks:abdominal magnetic resonance imaging(MRI)to computed tomography(CT),abdominal CT to MRI,cardiac MRI to CT,and cardiac CT to MRI.Notably,in the abdominal MRI to CT adaptation task,the VP-OS method achieved a remarkable improvement,increasing the average DICE score from 0.658 to 0.773(P<0.01)and reducing the average surface distance(ASD)from 3.489 to 2.961(P<0.01).Similarly,the VP-LD and VP-DPL methods also showed significant improvements over their base algorithms in both abdominal and cardiac MRI to CT tasks.Conclusions:This paper proposes VP-SFDA,a novel 2-stage framework for SFUDA in medical imaging,which achieves superior performance through input-specific visual prompts and batch normalization constraint for domain adaptation,coupled with denoising methods for enhanced results.Comparative experiments on 4 medical SFUDA tasks demonstrate that VO-SFDA surpasses existing methods,with ablation studies confirming the benefits of domain-specific patterns.展开更多
Deep learning now underpins many state-of-the-art systems for biomedical image and signal processing,enabling automated lesion detection,physiological monitoring,and therapy planning with accuracy that rivals expert p...Deep learning now underpins many state-of-the-art systems for biomedical image and signal processing,enabling automated lesion detection,physiological monitoring,and therapy planning with accuracy that rivals expert performance.This survey reviews the principal model families as convolutional,recurrent,generative,reinforcement,autoencoder,and transfer-learning approaches as emphasising how their architectural choices map to tasks such as segmentation,classification,reconstruction,and anomaly detection.A dedicated treatment of multimodal fusion networks shows how imaging features can be integrated with genomic profiles and clinical records to yield more robust,context-aware predictions.To support clinical adoption,we outline post-hoc explainability techniques(Grad-CAM,SHAP,LIME)and describe emerging intrinsically interpretable designs that expose decision logic to end users.Regulatory guidance from the U.S.FDA,the European Medicines Agency,and the EU AI Act is summarised,linking transparency and lifecycle-monitoring requirements to concrete development practices.Remaining challenges as data imbalance,computational cost,privacy constraints,and cross-domain generalization are discussed alongside promising solutions such as federated learning,uncertainty quantification,and lightweight 3-D architectures.The article therefore offers researchers,clinicians,and policymakers a concise,practice-oriented roadmap for deploying trustworthy deep-learning systems in healthcare.展开更多
Medical image segmentation has become a cornerstone for many healthcare applications,allowing for the automated extraction of critical information from images such as Computed Tomography(CT)scans,Magnetic Resonance Im...Medical image segmentation has become a cornerstone for many healthcare applications,allowing for the automated extraction of critical information from images such as Computed Tomography(CT)scans,Magnetic Resonance Imaging(MRIs),and X-rays.The introduction of U-Net in 2015 has significantly advanced segmentation capabilities,especially for small datasets commonly found in medical imaging.Since then,various modifications to the original U-Net architecture have been proposed to enhance segmentation accuracy and tackle challenges like class imbalance,data scarcity,and multi-modal image processing.This paper provides a detailed review and comparison of several U-Net-based architectures,focusing on their effectiveness in medical image segmentation tasks.We evaluate performance metrics such as Dice Similarity Coefficient(DSC)and Intersection over Union(IoU)across different U-Net variants including HmsU-Net,CrossU-Net,mResU-Net,and others.Our results indicate that architectural enhancements such as transformers,attention mechanisms,and residual connections improve segmentation performance across diverse medical imaging applications,including tumor detection,organ segmentation,and lesion identification.The study also identifies current challenges in the field,including data variability,limited dataset sizes,and issues with class imbalance.Based on these findings,the paper suggests potential future directions for improving the robustness and clinical applicability of U-Net-based models in medical image segmentation.展开更多
基金supported by the National Key R&D Program of China(No.2022YFC2504403)the National Natural Science Foundation of China(No.62172202)+1 种基金the Experiment Project of China Manned Space Program(No.HYZHXM01019)the Fundamental Research Funds for the Central Universities from Southeast University(No.3207032101C3)。
文摘Organoids possess immense potential for unraveling the intricate functions of human tissues and facilitating preclinical disease treatment.Their applications span from high-throughput drug screening to the modeling of complex diseases,with some even achieving clinical translation.Changes in the overall size,shape,boundary,and other morphological features of organoids provide a noninvasive method for assessing organoid drug sensitivity.However,the precise segmentation of organoids in bright-field microscopy images is made difficult by the complexity of the organoid morphology and interference,including overlapping organoids,bubbles,dust particles,and cell fragments.This paper introduces the precision organoid segmentation technique(POST),which is a deep-learning algorithm for segmenting challenging organoids under simple bright-field imaging conditions.Unlike existing methods,POST accurately segments each organoid and eliminates various artifacts encountered during organoid culturing and imaging.Furthermore,it is sensitive to and aligns with measurements of organoid activity in drug sensitivity experiments.POST is expected to be a valuable tool for drug screening using organoids owing to its capability of automatically and rapidly eliminating interfering substances and thereby streamlining the organoid analysis and drug screening process.
基金financially supported by the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2022WNLOKF009)the National Natural Science Foundation of China(No.62475216)+2 种基金the Key Research and Development Program of Shaanxi(No.2024GH-ZDXM-37)the Fujian Provincial Natural Science Foundation of China(No.2024J01060)the Startup Program of XMU,and the Fundamental Research Funds for the Central Universities.
文摘Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions.
基金supported under the 2024 Foshan City Self-Funded Science and Technology Innovation Project“Research on Image Segmentation Technology Based on Convolutional Neural Networks in Crop Images”(Project Number:2420001004686).
文摘The rising need for precision farming and sustainable land management has catalyzed the requirement for sophisticated means of deriving practical data from remote sensing images.Image segmentation,or the process of dividing the image into semantically relevant parts,has become a groundbreaking technology that allows resolving the problem of transitioning the pixel-level data to a parcel-level analysis.This review is a synthesis of the segmentation methods and their use in crop research and geospatial science.The architectures of pixel-based,object-based,and deep learning(convolutional neural networks,U-Net,Mask R-CNN,and Transformer models)are considered in terms of principles,capabilities,and limitations.Multi-spectral,hyperspectral,LiDAR,and SAR data are integrated to improve the efficiency of segmentation,allowing the possible delineation of fields,the classification of crops,health monitoring,monitoring of yields,and stress identification.In addition to agriculture,segmentation helps in land use and land cover mapping,identification of temporal change,monitoring of the environment,and is used in combination with GIS-based spatial modeling.Nevertheless,issues related to data heterogeneity,mixed pixels,computational requirements,and inadequate availability of labelled data still exist despite the major progress.The future directions involve multi-source data fusion,pixel-to-parcel pipeline automation,and predictive models based on AI,which are used to enhance its scalability,robustness,and the ability to monitor in real-time.This review makes it clear that the use of image segmentation as a tool in generating precision agriculture,sustainable land use,and informed geospatial.
文摘Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual information.Although the subsequent U-KAN model enhances nonlinear representation capabilities,it still faces challenges such as gradient vanishing during deep network training and spatial detail loss during feature downsampling,resulting in insufficient segmentation accuracy for edge structures and minute lesions.To address these challenges,this paper proposes the RE-UKAN model,which innovatively improves upon U-KAN.Firstly,a residual network is introduced into the encoder to effectively mitigate gradient vanishing through cross-layer identity mappings,thus enhancing modelling capabilities for complex pathological structures.Secondly,Efficient Local Attention(ELA)is integrated to suppress spatial detail loss during downsampling,thereby improving the perception of edge structures and minute lesions.Experimental results on four public datasets demonstrate that RE-UKAN outperforms existing medical image segmentation methods across multiple evaluation metrics,with particularly outstanding performance on the TN-SCUI 2020 dataset,achieving IoU of 88.18%and Dice of 93.57%.Compared to the baseline model,it achieves improvements of 3.05%and 1.72%,respectively.These results fully demonstrate RE-UKAN’s superior detail retention capability and boundary recognition accuracy in complex medical image segmentation tasks,providing a reliable solution for clinical precision segmentation.
基金funded by the Research Project:THTETN.05/24-25,VietnamAcademy of Science and Technology.
文摘Satellite image segmentation plays a crucial role in remote sensing,supporting applications such as environmental monitoring,land use analysis,and disaster management.However,traditional segmentation methods often rely on large amounts of labeled data,which are costly and time-consuming to obtain,especially in largescale or dynamic environments.To address this challenge,we propose the Semi-Supervised Multi-View Picture Fuzzy Clustering(SS-MPFC)algorithm,which improves segmentation accuracy and robustness,particularly in complex and uncertain remote sensing scenarios.SS-MPFC unifies three paradigms:semi-supervised learning,multi-view clustering,and picture fuzzy set theory.This integration allows the model to effectively utilize a small number of labeled samples,fuse complementary information from multiple data views,and handle the ambiguity and uncertainty inherent in satellite imagery.We design a novel objective function that jointly incorporates picture fuzzy membership functions across multiple views of the data,and embeds pairwise semi-supervised constraints(must-link and cannot-link)directly into the clustering process to enhance segmentation accuracy.Experiments conducted on several benchmark satellite datasets demonstrate that SS-MPFC significantly outperforms existing state-of-the-art methods in segmentation accuracy,noise robustness,and semantic interpretability.On the Augsburg dataset,SS-MPFC achieves a Purity of 0.8158 and an Accuracy of 0.6860,highlighting its outstanding robustness and efficiency.These results demonstrate that SSMPFC offers a scalable and effective solution for real-world satellite-based monitoring systems,particularly in scenarios where rapid annotation is infeasible,such as wildfire tracking,agricultural monitoring,and dynamic urban mapping.
基金National Natural Science Foundation of China under Grants No.62171047,U22B2001,62271065,62001051Beijing Natural Science Foundation under Grant L223027BUPT Excellent Ph.D Students Foundation under Grants CX2021114。
文摘This article studies the problem of image segmentation-based semantic communication in autonomous driving.In real traffic scenes,the detecting of objects(e.g.,vehicles and pedestrians)is more important to guarantee driving safety,which is always ignored in existing works.Therefore,we propose a vehicular image segmentation-oriented semantic communication system,termed VIS-SemCom,focusing on transmitting and recovering image semantic features of high-important objects to reduce transmission redundancy.First,we develop a semantic codec based on Swin Transformer architecture,which expands the perceptual field thus improving the segmentation accuracy.To highlight the important objects'accuracy,we propose a multi-scale semantic extraction method by assigning the number of Swin Transformer blocks for diverse resolution semantic features.Also,an importance-aware loss incorporating important levels is devised,and an online hard example mining(OHEM)strategy is proposed to handle small sample issues in the dataset.Finally,experimental results demonstrate that the proposed VIS-SemCom can achieve a significant mean intersection over union(mIoU)performance in the SNR regions,a reduction of transmitted data volume by about 60%at 60%mIoU,and improve the segmentation accuracy of important objects,compared to baseline image communication.
文摘Multilevel image segmentation is a critical task in image analysis,which imposes high requirements on the global search capability and convergence efficiency of segmentation algorithms.In this paper,an improved Artificial Protozoa Optimization algorithm,termed the two-stage Taguchi-assisted Gaussian–Levy Artificial Protozoa Optimization(TGAPO)algorithm,is proposed and applied tomultilevel image segmentation.The proposed algorithm adopts a two-stage evolutionary mechanism.In the first stage,Gaussian perturbation is introduced to enhance local search capability;in the second stage,Levy flight is incorporated to expand the global search range;and finally,the Taguchi strategy is employed to further refine the optimal solution.Consequently,the global optimization performance and robustness of the algorithm are significantly improved.To evaluate the effectiveness of the proposed TGAPO algorithm,comparative experiments are conducted with representative optimization algorithms,including the Grey Wolf Optimizer(GWO)and Particle Swarm Optimization(PSO),in the context ofmultilevel image segmentation.The segmentation quality is assessed using the minimum cross-entropy function as the performance metric.Experimental results demonstrate that the TGAPO algorithm outperforms the comparison algorithms in terms of segmentation accuracy and convergence speed,and exhibits superior stability in high-threshold segmentation tasks.Furthermore,the proposedmethod achieves excellentmulti-threshold segmentation performance for color images and shows strong potential for practical applications.
基金supported by the Autonomous Government of Andalusia(Spain)under project UMA20-FEDERJA-108also by the Ministry of Science and Innovation of Spain,grant number PID2022-136764OA-I00+1 种基金It includes funds fromthe European Regional Development Fund(ERDF),It is also partially supported by the Fundación Unicaja(PUNI-003_2023)the Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND(ATECH-25-02).
文摘Automatic and accurate medical image segmentation remains a fundamental task in computer-aided diagnosis and treatment planning.Recent advances in foundation models,such as the medical-focused Segment AnythingModel(MedSAM),have demonstrated strong performance but face challenges inmanymedical applications due to anatomical complexity and a limited domain-specific prompt.Thiswork introduces amethodology that enhances segmentation robustness and precision by automatically generating multiple informative point prompts,rather than relying on single inputs.The proposed approach randomly samples sets of spatially distributed point prompts based on image features,enabling MedSAM to better capture fine-grained anatomical structures and boundaries.During inference,probability maps are aggregated to reduce local misclassifications without additional model training.Extensive experiments on various computed tomography(CT)and magnetic resonance imaging(MRI)datasets demonstrate improvements in Dice Similarity Coefficient(DSC)and Normalized Surface Dice(NSD)metrics compared to baseline SAM and Scribble Prompt models.A semi-automatic point sampling version based on the ground truth segmentations yielded enhanced results,achieving up to 92.1%DSC and 86.6%NSD,with significant gains in delineating complex organs such as the pancreas,colon,kidney,and brain tumours.The main novelty of our method consists of effectively combining the results of multiple point prompts into the medical segmentation pipeline so that single-point prompt methods are outperformed.Overall,the proposed model offers a straightforward yet effective approach to improve medical image segmentation performance while maintaining computational efficiency.
基金supported by the Guangdong Pharmaceutical University 2024 Higher Education Research Projects(GKP202403,GMP202402)the Guangdong Pharmaceutical University College Students’Innovation and Entrepreneurship Training Programs(Grant No.202504302033,202504302034,202504302036,and 202504302244).
文摘Background:Diabetic macular edema is a prevalent retinal condition and a leading cause of visual impairment among diabetic patients’Early detection of affected areas is beneficial for effective diagnosis and treatment.Traditionally,diagnosis relies on optical coherence tomography imaging technology interpreted by ophthalmologists.However,this manual image interpretation is often slow and subjective.Therefore,developing automated segmentation for macular edema images is essential to enhance to improve the diagnosis efficiency and accuracy.Methods:In order to improve clinical diagnostic efficiency and accuracy,we proposed a SegNet network structure integrated with a convolutional block attention module(CBAM).This network introduces a multi-scale input module,the CBAM attention mechanism,and jump connection.The multi-scale input module enhances the network’s perceptual capabilities,while the lightweight CBAM effectively fuses relevant features across channels and spatial dimensions,allowing for better learning of varying information levels.Results:Experimental results demonstrate that the proposed network achieves an IoU of 80.127%and an accuracy of 99.162%.Compared to the traditional segmentation network,this model has fewer parameters,faster training and testing speed,and superior performance on semantic segmentation tasks,indicating its highly practical applicability.Conclusion:The C-SegNet proposed in this study enables accurate segmentation of Diabetic macular edema lesion images,which facilitates quicker diagnosis for healthcare professionals.
基金funded by the National Natural Science Foundation of China(Grant No.6240072655)the Hubei Provincial Key Research and Development Program(Grant No.2023BCB151)+1 种基金the Wuhan Natural Science Foundation Exploration Program(Chenguang Program,Grant No.2024040801020202)the Natural Science Foundation of Hubei Province of China(Grant No.2025AFB148).
文摘Image segmentation is attracting increasing attention in the field of medical image analysis.Since widespread utilization across various medical applications,ensuring and improving segmentation accuracy has become a crucial topic of research.With advances in deep learning,researchers have developed numerous methods that combine Transformers and convolutional neural networks(CNNs)to create highly accurate models for medical image segmentation.However,efforts to further enhance accuracy by developing larger and more complex models or training with more extensive datasets,significantly increase computational resource consumption.To address this problem,we propose BiCLIP-nnFormer(the prefix"Bi"refers to the use of two distinct CLIP models),a virtual multimodal instrument that leverages CLIP models to enhance the segmentation performance of a medical segmentation model nnFormer.Since two CLIP models(PMC-CLIP and CoCa-CLIP)are pre-trained on large datasets,they do not require additional training,thus conserving computation resources.These models are used offline to extract image and text embeddings from medical images.These embeddings are then processed by the proposed 3D CLIP adapter,which adapts the CLIP knowledge for segmentation tasks by fine-tuning.Finally,the adapted embeddings are fused with feature maps extracted from the nnFormer encoder for generating predicted masks.This process enriches the representation capabilities of the feature maps by integrating global multimodal information,leading to more precise segmentation predictions.We demonstrate the superiority of BiCLIP-nnFormer and the effectiveness of using CLIP models to enhance nnFormer through experiments on two public datasets,namely the Synapse multi-organ segmentation dataset(Synapse)and the Automatic Cardiac Diagnosis Challenge dataset(ACDC),as well as a self-annotated lung multi-category segmentation dataset(LMCS).
基金supported by the National Key Research and Development Project of China(No.2023YFB3709605)the National Natural Science Foundation of China(No.62073193)the National College Student Innovation Training Program(No.202310422122)。
文摘Potential high-temperature risks exist in heat-prone components of electric moped charging devices,such as sockets,interfaces,and controllers.Traditional detection methods have limitations in terms of real-time performance and monitoring scope.To address this,a temperature detection method based on infrared image processing has been proposed:utilizing the median filtering algorithm to denoise the original infrared image,then applying an image segmentation algorithm to divide the image.
基金supported by the National Natural Science(No.U19A2063)the Jilin Provincial Development Program of Science and Technology (No.20230201080GX)the Jilin Province Education Department Scientific Research Project (No.JJKH20230851KJ)。
文摘The visual noise of each light intensity area is different when the image is drawn by Monte Carlo method.However,the existing denoising algorithms have limited denoising performance under complex lighting conditions and are easy to lose detailed information.So we propose a rendered image denoising method with filtering guided by lighting information.First,we design an image segmentation algorithm based on lighting information to segment the image into different illumination areas.Then,we establish the parameter prediction model guided by lighting information for filtering(PGLF)to predict the filtering parameters of different illumination areas.For different illumination areas,we use these filtering parameters to construct area filters,and the filters are guided by the lighting information to perform sub-area filtering.Finally,the filtering results are fused with auxiliary features to output denoised images for improving the overall denoising effect of the image.Under the physically based rendering tool(PBRT)scene and Tungsten dataset,the experimental results show that compared with other guided filtering denoising methods,our method improves the peak signal-to-noise ratio(PSNR)metrics by 4.2164 dB on average and the structural similarity index(SSIM)metrics by 7.8%on average.This shows that our method can better reduce the noise in complex lighting scenesand improvethe imagequality.
基金Natural Science Foundation of Zhejiang Province,Grant/Award Number:LY23F020025Science and Technology Commissioner Program of Huzhou,Grant/Award Number:2023GZ42Sichuan Provincial Science and Technology Support Program,Grant/Award Numbers:2023ZHCG0005,2023ZHCG0008。
文摘Data augmentation plays an important role in training deep neural model by expanding the size and diversity of the dataset.Initially,data augmentation mainly involved some simple transformations of images.Later,in order to increase the diversity and complexity of data,more advanced methods appeared and evolved to sophisticated generative models.However,these methods required a mass of computation of training or searching.In this paper,a novel training-free method that utilises the Pre-Trained Segment Anything Model(SAM)model as a data augmentation tool(PTSAM-DA)is proposed to generate the augmented annotations for images.Without the need for training,it obtains prompt boxes from the original annotations and then feeds the boxes to the pre-trained SAM to generate diverse and improved annotations.In this way,annotations are augmented more ingenious than simple manipulations without incurring huge computation for training a data augmentation model.Multiple comparative experiments on three datasets are conducted,including an in-house dataset,ADE20K and COCO2017.On this in-house dataset,namely Agricultural Plot Segmentation Dataset,maximum improvements of 3.77%and 8.92%are gained in two mainstream metrics,mIoU and mAcc,respectively.Consequently,large vision models like SAM are proven to be promising not only in image segmentation but also in data augmentation.
基金supported by the Natural Science Foundation of the Anhui Higher Education Institutions of China(Grant Nos.2023AH040149 and 2024AH051915)the Anhui Provincial Natural Science Foundation(Grant No.2208085MF168)+1 种基金the Science and Technology Innovation Tackle Plan Project of Maanshan(Grant No.2024RGZN001)the Scientific Research Fund Project of Anhui Medical University(Grant No.2023xkj122).
文摘Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to the inability to effectively capture global information from images,CNNs can easily lead to loss of contours and textures in segmentation results.Notice that the transformer model can effectively capture the properties of long-range dependencies in the image,and furthermore,combining the CNN and the transformer can effectively extract local details and global contextual features of the image.Motivated by this,we propose a multi-branch and multi-scale attention network(M2ANet)for medical image segmentation,whose architecture consists of three components.Specifically,in the first component,we construct an adaptive multi-branch patch module for parallel extraction of image features to reduce information loss caused by downsampling.In the second component,we apply residual block to the well-known convolutional block attention module to enhance the network’s ability to recognize important features of images and alleviate the phenomenon of gradient vanishing.In the third component,we design a multi-scale feature fusion module,in which we adopt adaptive average pooling and position encoding to enhance contextual features,and then multi-head attention is introduced to further enrich feature representation.Finally,we validate the effectiveness and feasibility of the proposed M2ANet method through comparative experiments on four benchmark medical image segmentation datasets,particularly in the context of preserving contours and textures.
基金National Key Research and Development Program of China,Grant/Award Number:2018YFE0206900China Postdoctoral Science Foundation,Grant/Award Number:2023M731204+2 种基金The Open Project of Key Laboratory for Quality Evaluation of Ultrasound Surgical Equipment of National Medical Products Administration,Grant/Award Number:SMDTKL-2023-1-01The Hubei Province Key Research and Development Project,Grant/Award Number:2023BCB007CAAI-Huawei MindSpore Open Fund。
文摘Convolutional neural network(CNN)with the encoder-decoder structure is popular in medical image segmentation due to its excellent local feature extraction ability but it faces limitations in capturing the global feature.The transformer can extract the global information well but adapting it to small medical datasets is challenging and its computational complexity can be heavy.In this work,a serial and parallel network is proposed for the accurate 3D medical image segmentation by combining CNN and transformer and promoting feature interactions across various semantic levels.The core components of the proposed method include the cross window self-attention based transformer(CWST)and multi-scale local enhanced(MLE)modules.The CWST module enhances the global context understanding by partitioning 3D images into non-overlapping windows and calculating sparse global attention between windows.The MLE module selectively fuses features by computing the voxel attention between different branch features,and uses convolution to strengthen the dense local information.The experiments on the prostate,atrium,and pancreas MR/CT image datasets consistently demonstrate the advantage of the proposed method over six popular segmentation models in both qualitative evaluation and quantitative indexes such as dice similarity coefficient,Intersection over Union,95%Hausdorff distance and average symmetric surface distance.
基金supported by the Natural Science Foundation of China(No.41804112,author:Chengyun Song).
文摘Existing semi-supervisedmedical image segmentation algorithms use copy-paste data augmentation to correct the labeled-unlabeled data distribution mismatch.However,current copy-paste methods have three limitations:(1)training the model solely with copy-paste mixed pictures from labeled and unlabeled input loses a lot of labeled information;(2)low-quality pseudo-labels can cause confirmation bias in pseudo-supervised learning on unlabeled data;(3)the segmentation performance in low-contrast and local regions is less than optimal.We design a Stochastic Augmentation-Based Dual-Teaching Auxiliary Training Strategy(SADT),which enhances feature diversity and learns high-quality features to overcome these problems.To be more precise,SADT trains the Student Network by using pseudo-label-based training from Teacher Network 1 and supervised learning with labeled data,which prevents the loss of rare labeled data.We introduce a bi-directional copy-pastemask with progressive high-entropy filtering to reduce data distribution disparities and mitigate confirmation bias in pseudo-supervision.For the mixed images,Deep-Shallow Spatial Contrastive Learning(DSSCL)is proposed in the feature spaces of Teacher Network 2 and the Student Network to improve the segmentation capabilities in low-contrast and local areas.In this procedure,the features retrieved by the Student Network are subjected to a random feature perturbation technique.On two openly available datasets,extensive trials show that our proposed SADT performs much better than the state-ofthe-art semi-supervised medical segmentation techniques.Using only 10%of the labeled data for training,SADT was able to acquire a Dice score of 90.10%on the ACDC(Automatic Cardiac Diagnosis Challenge)dataset.
基金supported by the VTT Technical Research Centre of Finland and the work of Nayef Alqahtani is supported by the Deanship of Scientific Research,Vice Presidency for Graduate Studies and Scientific Research,King Faisal University,Saudi Arabia(Grant KFU251882).
文摘Lung cancer(LC)is a major cancer which accounts for higher mortality rates worldwide.Doctors utilise many imaging modalities for identifying lung tumours and their severity in earlier stages.Nowadays,machine learning(ML)and deep learning(DL)methodologies are utilised for the robust detection and prediction of lung tumours.Recently,multi modal imaging emerged as a robust technique for lung tumour detection by combining various imaging features.To cope with that,we propose a novel multi modal imaging technique named versatile scale malleable image integration and patch wise attention network(VSMI2−PANet)which adopts three imaging modalities named computed tomography(CT),magnetic resonance imaging(MRI)and single photon emission computed tomography(SPECT).The designed model accepts input from CT and MRI images and passes it to the VSMI2 module that is composed of three sub-modules named image cropping module,scale malleable convolution layer(SMCL)and PANet module.CT and MRI images are subjected to image cropping module in a parallel manner to crop the meaningful image patches and provide them to the SMCL module.The SMCL module is composed of adaptive convolutional layers that investigate those patches in a parallel manner by preserving the spatial information.The output from the SMCL is then fused and provided to the PANet module.The PANet module examines the fused patches by analysing its height,width and channels of the image patch.As a result,it provides an output as high-resolution spatial attention maps indicating the location of suspicious tumours.The high-resolution spatial attention maps are then provided as an input to the backbone module which uses light wave transformer(LWT)for segmenting the lung tumours into three classes,such as normal,benign and malignant.In addition,the LWT also accepts SPECT image as input for capturing the variations precisely to segment the lung tumours.The performance of the proposed model is validated using several performance metrics,such as accuracy,precision,recall,F1-score and AUC curve,and the results show that the proposed work outperforms the existing approaches.
基金supportted by the Natural Science Foundation of China(62394311,62394310)Beijing Natural Science Foundation(QY24034)National Biomedical Imaging Facility Grant and from the startup funds of Peking University Health Science Center.
文摘Background:Source-free unsupervised domain adaptation(SFUDA)methods aim to address the challenge of domain shift while preserving data privacy.Existing SFUDA approaches construct reliable and confident pseudo-labels for target-domain data through denoising methods,thereby guiding the training of the target-domain model.The effectiveness of denoising approaches is influenced by the degree of domain gap between the source and target domains.A marked shift can cause the pseudo-labels to be unreliable,even after applying denoising.Methods:We propose a novel 2-stage framework for SFUDA called visual prompt source-free domain adaptation(VP-SFDA).We propose input-specific visual prompt in the first stage,prompting process,which bridges the target-domain data to source-domain distribution.Our method utilizes visual prompts and batch normalization constraint to enable the alignment model to learn domainspecific knowledge and align the target-domain data with the source-domain contribution.The second stage is the adaptation process,which aims at optimizing the segmentation model from the source domain to the target domain.This is accomplished through the denoising techniques,ultimately enhancing the performance.Results:Our study presents a comparative analysis of several SFUDA techniques in the VPSFDA framework across 4 tasks:abdominal magnetic resonance imaging(MRI)to computed tomography(CT),abdominal CT to MRI,cardiac MRI to CT,and cardiac CT to MRI.Notably,in the abdominal MRI to CT adaptation task,the VP-OS method achieved a remarkable improvement,increasing the average DICE score from 0.658 to 0.773(P<0.01)and reducing the average surface distance(ASD)from 3.489 to 2.961(P<0.01).Similarly,the VP-LD and VP-DPL methods also showed significant improvements over their base algorithms in both abdominal and cardiac MRI to CT tasks.Conclusions:This paper proposes VP-SFDA,a novel 2-stage framework for SFUDA in medical imaging,which achieves superior performance through input-specific visual prompts and batch normalization constraint for domain adaptation,coupled with denoising methods for enhanced results.Comparative experiments on 4 medical SFUDA tasks demonstrate that VO-SFDA surpasses existing methods,with ablation studies confirming the benefits of domain-specific patterns.
基金supported by the Science Committee of the Ministry of Higher Education and Science of the Republic of Kazakhstan within the framework of grant AP23489899“Applying Deep Learning and Neuroimaging Methods for Brain Stroke Diagnosis”.
文摘Deep learning now underpins many state-of-the-art systems for biomedical image and signal processing,enabling automated lesion detection,physiological monitoring,and therapy planning with accuracy that rivals expert performance.This survey reviews the principal model families as convolutional,recurrent,generative,reinforcement,autoencoder,and transfer-learning approaches as emphasising how their architectural choices map to tasks such as segmentation,classification,reconstruction,and anomaly detection.A dedicated treatment of multimodal fusion networks shows how imaging features can be integrated with genomic profiles and clinical records to yield more robust,context-aware predictions.To support clinical adoption,we outline post-hoc explainability techniques(Grad-CAM,SHAP,LIME)and describe emerging intrinsically interpretable designs that expose decision logic to end users.Regulatory guidance from the U.S.FDA,the European Medicines Agency,and the EU AI Act is summarised,linking transparency and lifecycle-monitoring requirements to concrete development practices.Remaining challenges as data imbalance,computational cost,privacy constraints,and cross-domain generalization are discussed alongside promising solutions such as federated learning,uncertainty quantification,and lightweight 3-D architectures.The article therefore offers researchers,clinicians,and policymakers a concise,practice-oriented roadmap for deploying trustworthy deep-learning systems in healthcare.
文摘Medical image segmentation has become a cornerstone for many healthcare applications,allowing for the automated extraction of critical information from images such as Computed Tomography(CT)scans,Magnetic Resonance Imaging(MRIs),and X-rays.The introduction of U-Net in 2015 has significantly advanced segmentation capabilities,especially for small datasets commonly found in medical imaging.Since then,various modifications to the original U-Net architecture have been proposed to enhance segmentation accuracy and tackle challenges like class imbalance,data scarcity,and multi-modal image processing.This paper provides a detailed review and comparison of several U-Net-based architectures,focusing on their effectiveness in medical image segmentation tasks.We evaluate performance metrics such as Dice Similarity Coefficient(DSC)and Intersection over Union(IoU)across different U-Net variants including HmsU-Net,CrossU-Net,mResU-Net,and others.Our results indicate that architectural enhancements such as transformers,attention mechanisms,and residual connections improve segmentation performance across diverse medical imaging applications,including tumor detection,organ segmentation,and lesion identification.The study also identifies current challenges in the field,including data variability,limited dataset sizes,and issues with class imbalance.Based on these findings,the paper suggests potential future directions for improving the robustness and clinical applicability of U-Net-based models in medical image segmentation.
