Adhesion molecule CD146(100-130kDa)belongs to the immunoglobulin super family and it is originally identified as a biomarker for melanoma.Recently,CD146 is found as novel target molecule on endothelial cell and involv...Adhesion molecule CD146(100-130kDa)belongs to the immunoglobulin super family and it is originally identified as a biomarker for melanoma.Recently,CD146 is found as novel target molecule on endothelial cell and involved in tumor angiogenesis.Also CD146 is considered as critical molecule in cell invasion and anti-CD146 antibody could inhibit tumor metastasis and angiogenesis through its down regulation of NFk.In this report,we study the quantitative detection of the CD146 molecule in positive serum with the TIRIE biosensor.展开更多
文摘Adhesion molecule CD146(100-130kDa)belongs to the immunoglobulin super family and it is originally identified as a biomarker for melanoma.Recently,CD146 is found as novel target molecule on endothelial cell and involved in tumor angiogenesis.Also CD146 is considered as critical molecule in cell invasion and anti-CD146 antibody could inhibit tumor metastasis and angiogenesis through its down regulation of NFk.In this report,we study the quantitative detection of the CD146 molecule in positive serum with the TIRIE biosensor.
