Cells in the body are exposed to physiological and pathophysiological stimuli that encompass both chemical and mechanical factors,which coordinately modulate cellular functions. Compared to the large amount of informa...Cells in the body are exposed to physiological and pathophysiological stimuli that encompass both chemical and mechanical factors,which coordinately modulate cellular functions. Compared to the large amount of information on cellular re-展开更多
Theranostics is an appealing approach in precision medicine and it is still a critical challenge to design smart strategies which can precisely accumulate the functional probes/drugs into targeted disease areas.Cell-s...Theranostics is an appealing approach in precision medicine and it is still a critical challenge to design smart strategies which can precisely accumulate the functional probes/drugs into targeted disease areas.Cell-surface cascaded landing location is an effective strategy to develop functional drug-loading platforms to explore basic physiological processes at the cellular level and to facilitate the development of nanotheranostics for disease treatment.展开更多
基金supported in part by grants from NIH HL098472, CA139272, NS063405NSF CBET0846429,CMMI0800870the Wallace H Coulter Foundation,and the Beckman Laser Institute Inc
文摘Cells in the body are exposed to physiological and pathophysiological stimuli that encompass both chemical and mechanical factors,which coordinately modulate cellular functions. Compared to the large amount of information on cellular re-
基金supported by the Major State Basic Research Development Program of China(Nos.2017YFA0205201,2014CB744503,and 2013CB733802)the National Natural Science Foundation of China(NSFC)(Nos.81422023,81371596,51273165,and U1505221)
文摘Theranostics is an appealing approach in precision medicine and it is still a critical challenge to design smart strategies which can precisely accumulate the functional probes/drugs into targeted disease areas.Cell-surface cascaded landing location is an effective strategy to develop functional drug-loading platforms to explore basic physiological processes at the cellular level and to facilitate the development of nanotheranostics for disease treatment.