Context: The advent of Artificial Intelligence (AI) requires modeling prior to its implementation in algorithms for most human skills. This observation requires us to have a detailed and precise understanding of the i...Context: The advent of Artificial Intelligence (AI) requires modeling prior to its implementation in algorithms for most human skills. This observation requires us to have a detailed and precise understanding of the interfaces of verbal and emotional communications. The progress of AI is significant on the verbal level but modest in terms of the recognition of facial emotions even if this functionality is one of the oldest in humans and is omnipresent in our daily lives. Dysfunction in the ability for facial emotional expressions is present in many brain pathologies encountered by psychiatrists, neurologists, psychotherapists, mental health professionals including social workers. It cannot be objectively verified and measured due to a lack of reliable tools that are valid and consistently sensitive. Indeed, the articles in the scientific literature dealing with Visual-Facial-Emotions-Recognition (ViFaEmRe), suffer from the absence of 1) consensual and rational tools for continuous quantified measurement, 2) operational concepts. We have invented a software that can use computer-morphing attempting to respond to these two obstacles. It is identified as the Method of Analysis and Research of the Integration of Emotions (M.A.R.I.E.). Our primary goal is to use M.A.R.I.E. to understand the physiology of ViFaEmRe in normal healthy subjects by standardizing the measurements. Then, it will allow us to focus on subjects manifesting abnormalities in this ability. Our second goal is to make our contribution to the progress of AI hoping to add the dimension of recognition of facial emotional expressions. Objective: To study: 1) categorical vs dimensional aspects of recognition of ViFaEmRe, 2) universality vs idiosyncrasy, 3) immediate vs ambivalent Emotional-Decision-Making, 4) the Emotional-Fingerprint of a face and 5) creation of population references data. Methods: M.A.R.I.E. enables the rational, quantified measurement of Emotional Visual Acuity (EVA) in an individual observer and a population aged 20 to 70 years. Meanwhile, it can measure the range and intensity of expressed emotions through three Face- Tests, quantify the performance of a sample of 204 observers with hypernormal measures of cognition, “thymia” (defined elsewhere), and low levels of anxiety, and perform analysis of the six primary emotions. Results: We have individualized the following continuous parameters: 1) “Emotional-Visual- Acuity”, 2) “Visual-Emotional-Feeling”, 3) “Emotional-Quotient”, 4) “Emotional-Decision-Making”, 5) “Emotional-Decision-Making Graph” or “Individual-Gun-Trigger”, 6) “Emotional-Fingerprint” or “Key-graph”, 7) “Emotional-Fingerprint-Graph”, 8) detecting “misunderstanding” and 9) detecting “error”. This allowed us a taxonomy with coding of the face-emotion pair. Each face has specific measurements and graphics. The EVA improves from ages of 20 to 55 years, then decreases. It does not depend on the sex of the observer, nor the face studied. In addition, 1% of people endowed with normal intelligence do not recognize emotions. The categorical dimension is a variable for everyone. The range and intensity of ViFaEmRe is idiosyncratic and not universally uniform. The recognition of emotions is purely categorical for a single individual. It is dimensional for a population sample. Conclusions: Firstly, M.A.R.I.E. has made possible to bring out new concepts and new continuous measurements variables. The comparison between healthy and abnormal individuals makes it possible to take into consideration the significance of this line of study. From now on, these new functional parameters will allow us to identify and name “emotional” disorders or illnesses which can give additional dimension to behavioral disorders in all pathologies that affect the brain. Secondly, the ViFaEmRe is idiosyncratic, categorical, and a function of the identity of the observer and of the observed face. These findings stack up against Artificial Intelligence, which cannot have a globalist or regionalist algorithm that can be programmed into a robot, nor can AI compete with human abilities and judgment in this domain. *Here “Emotional disorders” refers to disorders of emotional expressions and recognition.展开更多
Context: The advent of Artificial Intelligence (AI) requires modeling prior to its implementation in algorithms for most human skills. This observation requires us to have a detailed and precise understanding of the i...Context: The advent of Artificial Intelligence (AI) requires modeling prior to its implementation in algorithms for most human skills. This observation requires us to have a detailed and precise understanding of the interfaces of verbal and emotional communications. The progress of AI is significant on the verbal level but modest in terms of the recognition of facial emotions even if this functionality is one of the oldest in humans and is omnipresent in our daily lives. Dysfunction in the ability for facial emotional expressions is present in many brain pathologies encountered by psychiatrists, neurologists, psychotherapists, mental health professionals including social workers. It cannot be objectively verified and measured due to a lack of reliable tools that are valid and consistently sensitive. Indeed, the articles in the scientific literature dealing with Visual-Facial-Emotions-Recognition (ViFaEmRe), suffer from the absence of 1) consensual and rational tools for continuous quantified measurement, 2) operational concepts. We have invented a software that can use computer-morphing attempting to respond to these two obstacles. It is identified as the Method of Analysis and Research of the Integration of Emotions (M.A.R.I.E.). Our primary goal is to use M.A.R.I.E. to understand the physiology of ViFaEmRe in normal healthy subjects by standardizing the measurements. Then, it will allow us to focus on subjects manifesting abnormalities in this ability. Our second goal is to make our contribution to the progress of AI hoping to add the dimension of recognition of facial emotional expressions. Objective: To study: 1) categorical vs dimensional aspects of recognition of ViFaEmRe, 2) universality vs idiosyncrasy, 3) immediate vs ambivalent Emotional-Decision-Making, 4) the Emotional-Fingerprint of a face and 5) creation of population references data. Methods: With M.A.R.I.E. enable a rational quantified measurement of Emotional-Visual-Acuity (EVA) of 1) a) an individual observer, b) in a population aged 20 to 70 years old, 2) measure the range and intensity of expressed emotions by 3 Face-Tests, 3) quantify the performance of a sample of 204 observers with hyper normal measures of cognition, “thymia,” (ibid. defined elsewhere) and low levels of anxiety 4) analysis of the 6 primary emotions. Results: We have individualized the following continuous parameters: 1) “Emotional-Visual-Acuity”, 2) “Visual-Emotional-Feeling”, 3) “Emotional-Quotient”, 4) “Emotional-Deci-sion-Making”, 5) “Emotional-Decision-Making Graph” or “Individual-Gun-Trigger”6) “Emotional-Fingerprint” or “Key-graph”, 7) “Emotional-Finger-print-Graph”, 8) detecting “misunderstanding” and 9) detecting “error”. This allowed us a taxonomy with coding of the face-emotion pair. Each face has specific measurements and graphics. The EVA improves from ages of 20 to 55 years, then decreases. It does not depend on the sex of the observer, nor the face studied. In addition, 1% of people endowed with normal intelligence do not recognize emotions. The categorical dimension is a variable for everyone. The range and intensity of ViFaEmRe is idiosyncratic and not universally uniform. The recognition of emotions is purely categorical for a single individual. It is dimensional for a population sample. Conclusions: Firstly, M.A.R.I.E. has made possible to bring out new concepts and new continuous measurements variables. The comparison between healthy and abnormal individuals makes it possible to take into consideration the significance of this line of study. From now on, these new functional parameters will allow us to identify and name “emotional” disorders or illnesses which can give additional dimension to behavioral disorders in all pathologies that affect the brain. Secondly, the ViFaEmRe is idiosyncratic, categorical, and a function of the identity of the observer and of the observed face. These findings stack up against Artificial Intelligence, which cannot have a globalist or regionalist algorithm that can be programmed into a robot, nor can AI compete with human abilities and judgment in this domain. *Here “Emotional disorders” refers to disorders of emotional expressions and recognition.展开更多
In accordance with previous reports, the sequences related to phosporylated protein segments occur in conserved variable domains of immunoglobulins including first of all certain N-terminally located segments. Consequ...In accordance with previous reports, the sequences related to phosporylated protein segments occur in conserved variable domains of immunoglobulins including first of all certain N-terminally located segments. Consequently, we look here for the sequences 1) composing human and mouse proteins different from antigen receptors, 2) identical with or highly similar to nucleotide sequence representatives of conserved variable immunoglobulin segments and 3) identical with or closely related to phosphorylation sites. More precisely, we searched for the corresponding actual pairs of DNA and protein sequence segments using five-step bilingual approach employing among others a) different types of BLAST searches, b) two in-principle-different machine-learning methods predicting phosphorylated sites and c) two large databases recording existing phosphorylation sites. The approach identified seven existing phosphorylation sites and thirty-seven related human and mouse segments achieving limits for several predictions or phylogenic parameters. Mostly serines phosporylated with ataxia-telangiectasia-related kinase (involved in regulation of DNA-double-strand-break repair) were indicated or predicted in this study. Hypermutation motifs, located in effective positions of the selected sequence segments, occurred significantly less frequently in transcribed than non-transcribed DNA strands suggesting thus the incidence of mutation events. In addition, marked differences between the numbers and proportions of human and mouse cancer-related sequence items were found in different steps of selection process. The possible role of hypermutation changes within the selected segments and the observed structural relationships are discussed here with respect to DNA damage, carcinogenesis, cancer vaccination, ageing and evolution. Taken together, our data represent additional and sometimes perhaps complementary information to the existing databases of empirically proven phosphorylation sites or pathogenically important spots.展开更多
The Denglou Cape, southwest of the Leizhou Peninsula, is the most typical tropical coast in the continent of China.The coastal geomorphic development basics of the geology and Quaternary environment change are discus...The Denglou Cape, southwest of the Leizhou Peninsula, is the most typical tropical coast in the continent of China.The coastal geomorphic development basics of the geology and Quaternary environment change are discussed. Aerial photograph interpretation with fieldwork is applied to draw the outlines of geomorphic types. Based on the investigative data, the exogenic forces and marine organism conditions concerning tropical coast development in the area are expounded, and coastal dynamo-deposition geomorphic bodies are analysed, mainly with sea cliff-abrasion platform,barrier-lagoon system, modern beach, coral reef and mangrove tidal flat, and the general process of coastal evolution at this area, as well as coastline changes since middle Holocene transgression.展开更多
<strong>Introduction:</strong> Modern family planning methods (MFPM) prevent unwanted pregnancies, reduce fertility rate, and increase the interval between pregnancies. They prevent pregnancy by preventing...<strong>Introduction:</strong> Modern family planning methods (MFPM) prevent unwanted pregnancies, reduce fertility rate, and increase the interval between pregnancies. They prevent pregnancy by preventing fertilization or implantation of the fertilized ovum. MFPM include tubal ligation (TL), vasectomy, oral contraceptive pills, the intrauterine contraceptive device (IUCD), depot injections, sub-dermal implants, and male and female condoms. <strong>Objective: </strong>To determine the level of knowledge of modern family planning methods (MFPM) among women of reproductive age (18 - 49 years) at the Mathari North Health Center in Nairobi County, Kenya. <strong>Methods: </strong>The study conducted among women of reproductive age at Mathare North Health Center in Nairobi was a cross-sectional descriptive survey between March 2016 and November 2018. It provided both qualitative and quantitative data. The sample size comprised of 274 women of reproductive age,<em> i.e.</em> (18 - 49 years) attending antenatal and postnatal clinics at the facility. Those excluded were women below 18 years of age, as they could not give consent according to Kenyan Laws. The data were collected using an interviewer-administered structured questionnaire, which consisted of socio-demographic and characteristics, knowledge of modern family planning methods and distance from the facility. Likert scale was used to ensure that data was tabulated on daily basis and subjected to statistical manipulation using Statistical Package for Social Sciences (SPSS). <strong>Results:</strong> The four leading MFPM in use in order of acceptability were injectables, implants, intrauterine contraceptive device and pills in that order. 91% of respondents were aware or had heard about modern family planning methods. Level of education of mother and father were the two variables that influenced the uptake of MFPM with <em>p</em>-values of 0.0260 and 0.025, respectively. The study further found that knowledge of MFPM had a significant influence on their assimilation and utilization. All secondary variables considered in the research exhibit a substantial relationship concerning the use of MFPM. <strong>Conclusion:</strong> Communities around Mathari North Health Center need to be given information;education and counselling on MFPM to enable them make an informed decision and choice on their preferred method of family planning.展开更多
Objective: To examine and measure the decision-making processes involved in Visual Recognition of Facial Emotional Expressions (VRFEE) and to study the effects of demographic factors on this process. Method: We evalua...Objective: To examine and measure the decision-making processes involved in Visual Recognition of Facial Emotional Expressions (VRFEE) and to study the effects of demographic factors on this process. Method: We evaluated a newly designed software application (M.A.R.I.E.) that permits computerized metric measurement of VRFEE. We administered it to 204 cognitively normal participants ranging in age from 20 to 70 years. Results: We established normative values for the recognition of anger, disgust, joy, fear, surprise and sadness expressed on the faces of three individuals. There was a significant difference in the: 1) measurement (F (8.189) = 3896, p = 0.0001);2) education level (x2(12) = 28.4, p = 0.005);3) face (F(2.195) = 10, p = 0.0001);4)series (F (8.189)=28, p = 0.0001);5) interaction between the identity and recognition of emotions (F (16, 181 =11, p = 0.0001). However, performance did not differ according to: 1) age (F (6.19669) = 1.35, p = 0.2) or 2) level of education (F (1, 1587) = 0.6, p = 0.4). Conclusions: In healthy participants, the VRFEE remains stable throughout the lifespan when cognitive functions remain optimal. Disgust, sadness, fear, and joy seem to be the four most easily recognized facial emotions, while anger and surprise are not easily recognized. Visual recognition of disgust and fear is independent of aging. The characteristics of a face have a significant influence on the ease with which people recognize expressed emotions (idiosyncrasy). Perception and recognition of emotions is categorical, even when the facial images are integrated in a spectrum of morphs reflecting two different emotions on either side.展开更多
This paper begins with the overthrow of the concept of combining ability in crossbreeding by the concept of heritability.The reason is that general combining ability changes with the number and kind of pure strains in...This paper begins with the overthrow of the concept of combining ability in crossbreeding by the concept of heritability.The reason is that general combining ability changes with the number and kind of pure strains in the foundation stock and hence special combining ability changes also,so that work with different kinds of pure strains in the foundation stock cannot be compared.Hence combining ability is useless as a parameter to predict the amount of heterosis expected in the next generation.On the other hand,since each cross has a separate heritability,it can be applied to a cross population just as successfully as in purebreeding.Since the same concept holds in both cases,resort to any other concept would be superfluous.That's why combining ability must be rejected.Another reason(not given in the full text)is,an infinite number of pure strains would be required in the foundation stock for its results to be comparable with those of the heritability theory,which disposes of its utility altogether.The main content of the thesis is then the centennial enigma of heterosis can be resolved by Descarte's theoretic method of deduction.Accordingly we start from the definition of heterosis.H=F¡-MP,where H is heterosis,F,is the first generation offspring,MP is the mean of the parents or midparent,and from the use of a binomial random variable and its extention to the multinomial case derive the basic relations of heterosis with its components.Starting with second degree statistics,we obtain Vn=Vr,-2cov(F,,MP)+Vup,where V and cov stand for variance and covariance.The equations of heterosis are v„=(1/2)Na²+(1/4)Nd’+Vr(F,)=additive dominance F,epistasis Vup=(1/2)Na’+(1/2)V1,additive parental epistasis V„=(1/4)Nd’+V(F)+(1/2)V1,dominance F,epistasis parental epistasis.where N is number of genes controlling a trait,a=(P1-P,)12,d is deviation from midparent,while the variance components are all indicated by their names under the repective terms.It turns out that all these can be easily computed from the data so that the problem becomes a simple one which any college student may solve.In other words,the right answers are found when the right questions are asked.Who had ever shown that the heritability principle is inapplicable in crossbreeding,e.g.,in a crossing of two pure strains?From this cue arose the realization that the F,of a cross of two pure strains must also be a Mendelian population,with p and q both equal to 1/2 which simplifies the algebra outright.This Heritability Theory of Heterosis,or HTH in capital letters,re-sts on 2 initial anguments:1)Since 0.5+0.5=1,crossing two pure strains gives a population which is only a special case of pure-breeding,thereforea heritability coefficient must exist for the F1;2)Our problem reduces to that of finding that coefficient;the an-swer is given by the additive component divided by Ve.,i.e.,(1/2)No'1 Vp..which is readily found from the solution of the het-erosis equations.Thus the elemnal enigma of heterosis is resolved!This happened at the end of the 20th century.We now come to the second point of the discovery,the new genetic parameter crossheritability which will rise in size with the increase of the number of times it's used and form the link between breeding and evolution.The advent of the Age of Evolution Engineering in the 21st century marks a totally new era,showing that artificial will ultimately supercede natural selection,with the long span of time element eliminated.For agriculture at least,it means there is no limit to the increase of food supply by the new method,with the concentra-tion of desirable genes by hybridization in place of the old theory of their fixation.Genetic gain is achieved through artificial selec-tion,with an 80%saving of time,labor and cost by adoption of the new method.Applied to a further increase in all kinds of agri-cultural products including hybrd rice,it means that a huge eacalation,in fact a New Green Revolution,on a much langer scale than that of any such before,is in view,provided it is adopted in our research and educational institutions as early as possible,ere its spread elsewhere.The possibilities from the evolution point of view can only be pictured by science fiction.展开更多
The underpinning problems of deep-water facies still remain unresolved.(1) The Tb, Tc, and Td divisions of the turbidite facies model, with traction structures, are an integral part of the "Bouma Sequence"(T...The underpinning problems of deep-water facies still remain unresolved.(1) The Tb, Tc, and Td divisions of the turbidite facies model, with traction structures, are an integral part of the "Bouma Sequence"(Ta, Tb, Tc, Td, Te).However, deposits of thermohaline contour currents, wind-driven bottom currents, deep-marine tidal currents, and baroclinic currents(internal waves and tides) also develop discrete rippled units, mimicking Tc.(2) The application of "cut-out" logic of sequences, which was originally introduced for the "Bouma Sequence", with sharp basal contacts and sandy divisions containing well-developed traction structures, to muddy contorts with gradational basal contacts and an absence of well-developed traction structures is incongruent.(3) The presence of five internal divisions and hiatus in the muddy contoured facies model is in dispute.(4) Intersection of along slope contour currents with down slope sediment-gravity flows, triggering hybrid flows, also develops traction structures.(5) The comparison of genuine hybrid flows with down slope flow transformation of gravity flows is inconsistent with etymology of the term "hybrid".(6) A reexamination of the Annot Sandstone at the Peira Cava type locality in SE France fails to validate either the orthodoxy of five internal divisions of the "Bouma Sequence" or their origin by turbidity currents. For example, the "Ta" division is composed of amalgamated units with inverse grading and floating mudstone clasts, suggesting a mass-transport deposit(MTD). The "Tb" and "Tc" divisions are composed of double mud layers and sigmoidal cross bedding, respectively, which suggest a tidalite origin.(7) Although it was reasonable to introduce a simplistic "Bouma Sequence" in 1962, at a time of limited knowledge on deep-water processes, it is obsolete now in 2021 to apply this model to the rock record amid a wealth of new knowledge.(8)The disconnect between 12 observed, but questionable, modern turbidity currents and over 10,000 interpreted ancient turbidites defies the doctrine of uniformitarianism. This disconnect is attributed to routine application of genetic facies models, without a pragmatic interpretation of empirical data.(9) A suggested solution to these problems is to interpret traction structures in the sedimentary record pragmatically on the basis of empirical field and experimental evidence, without any built-in bias using facies models, such as the "Bouma Sequence".(10) Until reliable criteria are developed to distinguish traction structures of each type of bottom currents based on uniformitarianism, a general term "BCRS"(i.e., bottom-current reworked sands) is appropriate for deposits of all four kinds of bottom currents.展开更多
The typeⅡ codes have been studied widely in applications since their appearance. With analysis of the algebraic structure of finite field of order 4 （i.e., GF（4））, some necessary and sufficient conditions that a ...The typeⅡ codes have been studied widely in applications since their appearance. With analysis of the algebraic structure of finite field of order 4 （i.e., GF（4））, some necessary and sufficient conditions that a generalized H-code （i.e., GH-code） is a type Ⅱ code over GF（4） are given in this article, and an efficient and simple method to generate type Ⅱ codes from GH-codes over GF（4） is shown. The conclusions further extend the coding theory of type Ⅱ.展开更多
The pristine point of zero charge(p.p.z.c)and zeta potential as a function of pH of boehmite oxide/hydroxide(α-Al_(2)O_(3)·H_(2)O)have been determined for three filter media.The active component in the first two...The pristine point of zero charge(p.p.z.c)and zeta potential as a function of pH of boehmite oxide/hydroxide(α-Al_(2)O_(3)·H_(2)O)have been determined for three filter media.The active component in the first two filter media is boehmite nanofibers,only 2 nm in diameter and about 300 nm long.Boehmite nanofibers create high zeta potential(ζtrue≥46 mV)in aqueous solutions in the pH range of 3–8.The p.p.z.c.values were determined to be 11.60±0.15 for nanofibers grafted onto microglass fibers and 11.40±0.15 for agglomerated nanofibers.In the third filter media,a boehmite nanolayer in the form of monocrystalline oxide/hydroxide with a thickness of approximately 1.2 nm is electroadhesively deposited onto siliceous support material with large surface area of about 50 m^(2)/g,therefore forming a highly electropositive composite of boehmite nanolayer on the second highly electronegative solid.Boehmite’s oxide-hydroxide nanolayer surface creates high zeta potential(ζtrue≥50 mV)in aqueous solutions in the pH range of 3–8.The p.p.z.c.value was determined to be 11.38±0.15.The reported values are within accuracy,but they are much higher than the values reported in the literature.X-ray powder diffraction data were supplemented by microscopy,infrared spectroscopy in order to characterize fully synthetic boehmite surfaces.展开更多
文摘Context: The advent of Artificial Intelligence (AI) requires modeling prior to its implementation in algorithms for most human skills. This observation requires us to have a detailed and precise understanding of the interfaces of verbal and emotional communications. The progress of AI is significant on the verbal level but modest in terms of the recognition of facial emotions even if this functionality is one of the oldest in humans and is omnipresent in our daily lives. Dysfunction in the ability for facial emotional expressions is present in many brain pathologies encountered by psychiatrists, neurologists, psychotherapists, mental health professionals including social workers. It cannot be objectively verified and measured due to a lack of reliable tools that are valid and consistently sensitive. Indeed, the articles in the scientific literature dealing with Visual-Facial-Emotions-Recognition (ViFaEmRe), suffer from the absence of 1) consensual and rational tools for continuous quantified measurement, 2) operational concepts. We have invented a software that can use computer-morphing attempting to respond to these two obstacles. It is identified as the Method of Analysis and Research of the Integration of Emotions (M.A.R.I.E.). Our primary goal is to use M.A.R.I.E. to understand the physiology of ViFaEmRe in normal healthy subjects by standardizing the measurements. Then, it will allow us to focus on subjects manifesting abnormalities in this ability. Our second goal is to make our contribution to the progress of AI hoping to add the dimension of recognition of facial emotional expressions. Objective: To study: 1) categorical vs dimensional aspects of recognition of ViFaEmRe, 2) universality vs idiosyncrasy, 3) immediate vs ambivalent Emotional-Decision-Making, 4) the Emotional-Fingerprint of a face and 5) creation of population references data. Methods: M.A.R.I.E. enables the rational, quantified measurement of Emotional Visual Acuity (EVA) in an individual observer and a population aged 20 to 70 years. Meanwhile, it can measure the range and intensity of expressed emotions through three Face- Tests, quantify the performance of a sample of 204 observers with hypernormal measures of cognition, “thymia” (defined elsewhere), and low levels of anxiety, and perform analysis of the six primary emotions. Results: We have individualized the following continuous parameters: 1) “Emotional-Visual- Acuity”, 2) “Visual-Emotional-Feeling”, 3) “Emotional-Quotient”, 4) “Emotional-Decision-Making”, 5) “Emotional-Decision-Making Graph” or “Individual-Gun-Trigger”, 6) “Emotional-Fingerprint” or “Key-graph”, 7) “Emotional-Fingerprint-Graph”, 8) detecting “misunderstanding” and 9) detecting “error”. This allowed us a taxonomy with coding of the face-emotion pair. Each face has specific measurements and graphics. The EVA improves from ages of 20 to 55 years, then decreases. It does not depend on the sex of the observer, nor the face studied. In addition, 1% of people endowed with normal intelligence do not recognize emotions. The categorical dimension is a variable for everyone. The range and intensity of ViFaEmRe is idiosyncratic and not universally uniform. The recognition of emotions is purely categorical for a single individual. It is dimensional for a population sample. Conclusions: Firstly, M.A.R.I.E. has made possible to bring out new concepts and new continuous measurements variables. The comparison between healthy and abnormal individuals makes it possible to take into consideration the significance of this line of study. From now on, these new functional parameters will allow us to identify and name “emotional” disorders or illnesses which can give additional dimension to behavioral disorders in all pathologies that affect the brain. Secondly, the ViFaEmRe is idiosyncratic, categorical, and a function of the identity of the observer and of the observed face. These findings stack up against Artificial Intelligence, which cannot have a globalist or regionalist algorithm that can be programmed into a robot, nor can AI compete with human abilities and judgment in this domain. *Here “Emotional disorders” refers to disorders of emotional expressions and recognition.
文摘Context: The advent of Artificial Intelligence (AI) requires modeling prior to its implementation in algorithms for most human skills. This observation requires us to have a detailed and precise understanding of the interfaces of verbal and emotional communications. The progress of AI is significant on the verbal level but modest in terms of the recognition of facial emotions even if this functionality is one of the oldest in humans and is omnipresent in our daily lives. Dysfunction in the ability for facial emotional expressions is present in many brain pathologies encountered by psychiatrists, neurologists, psychotherapists, mental health professionals including social workers. It cannot be objectively verified and measured due to a lack of reliable tools that are valid and consistently sensitive. Indeed, the articles in the scientific literature dealing with Visual-Facial-Emotions-Recognition (ViFaEmRe), suffer from the absence of 1) consensual and rational tools for continuous quantified measurement, 2) operational concepts. We have invented a software that can use computer-morphing attempting to respond to these two obstacles. It is identified as the Method of Analysis and Research of the Integration of Emotions (M.A.R.I.E.). Our primary goal is to use M.A.R.I.E. to understand the physiology of ViFaEmRe in normal healthy subjects by standardizing the measurements. Then, it will allow us to focus on subjects manifesting abnormalities in this ability. Our second goal is to make our contribution to the progress of AI hoping to add the dimension of recognition of facial emotional expressions. Objective: To study: 1) categorical vs dimensional aspects of recognition of ViFaEmRe, 2) universality vs idiosyncrasy, 3) immediate vs ambivalent Emotional-Decision-Making, 4) the Emotional-Fingerprint of a face and 5) creation of population references data. Methods: With M.A.R.I.E. enable a rational quantified measurement of Emotional-Visual-Acuity (EVA) of 1) a) an individual observer, b) in a population aged 20 to 70 years old, 2) measure the range and intensity of expressed emotions by 3 Face-Tests, 3) quantify the performance of a sample of 204 observers with hyper normal measures of cognition, “thymia,” (ibid. defined elsewhere) and low levels of anxiety 4) analysis of the 6 primary emotions. Results: We have individualized the following continuous parameters: 1) “Emotional-Visual-Acuity”, 2) “Visual-Emotional-Feeling”, 3) “Emotional-Quotient”, 4) “Emotional-Deci-sion-Making”, 5) “Emotional-Decision-Making Graph” or “Individual-Gun-Trigger”6) “Emotional-Fingerprint” or “Key-graph”, 7) “Emotional-Finger-print-Graph”, 8) detecting “misunderstanding” and 9) detecting “error”. This allowed us a taxonomy with coding of the face-emotion pair. Each face has specific measurements and graphics. The EVA improves from ages of 20 to 55 years, then decreases. It does not depend on the sex of the observer, nor the face studied. In addition, 1% of people endowed with normal intelligence do not recognize emotions. The categorical dimension is a variable for everyone. The range and intensity of ViFaEmRe is idiosyncratic and not universally uniform. The recognition of emotions is purely categorical for a single individual. It is dimensional for a population sample. Conclusions: Firstly, M.A.R.I.E. has made possible to bring out new concepts and new continuous measurements variables. The comparison between healthy and abnormal individuals makes it possible to take into consideration the significance of this line of study. From now on, these new functional parameters will allow us to identify and name “emotional” disorders or illnesses which can give additional dimension to behavioral disorders in all pathologies that affect the brain. Secondly, the ViFaEmRe is idiosyncratic, categorical, and a function of the identity of the observer and of the observed face. These findings stack up against Artificial Intelligence, which cannot have a globalist or regionalist algorithm that can be programmed into a robot, nor can AI compete with human abilities and judgment in this domain. *Here “Emotional disorders” refers to disorders of emotional expressions and recognition.
文摘In accordance with previous reports, the sequences related to phosporylated protein segments occur in conserved variable domains of immunoglobulins including first of all certain N-terminally located segments. Consequently, we look here for the sequences 1) composing human and mouse proteins different from antigen receptors, 2) identical with or highly similar to nucleotide sequence representatives of conserved variable immunoglobulin segments and 3) identical with or closely related to phosphorylation sites. More precisely, we searched for the corresponding actual pairs of DNA and protein sequence segments using five-step bilingual approach employing among others a) different types of BLAST searches, b) two in-principle-different machine-learning methods predicting phosphorylated sites and c) two large databases recording existing phosphorylation sites. The approach identified seven existing phosphorylation sites and thirty-seven related human and mouse segments achieving limits for several predictions or phylogenic parameters. Mostly serines phosporylated with ataxia-telangiectasia-related kinase (involved in regulation of DNA-double-strand-break repair) were indicated or predicted in this study. Hypermutation motifs, located in effective positions of the selected sequence segments, occurred significantly less frequently in transcribed than non-transcribed DNA strands suggesting thus the incidence of mutation events. In addition, marked differences between the numbers and proportions of human and mouse cancer-related sequence items were found in different steps of selection process. The possible role of hypermutation changes within the selected segments and the observed structural relationships are discussed here with respect to DNA damage, carcinogenesis, cancer vaccination, ageing and evolution. Taken together, our data represent additional and sometimes perhaps complementary information to the existing databases of empirically proven phosphorylation sites or pathogenically important spots.
文摘The Denglou Cape, southwest of the Leizhou Peninsula, is the most typical tropical coast in the continent of China.The coastal geomorphic development basics of the geology and Quaternary environment change are discussed. Aerial photograph interpretation with fieldwork is applied to draw the outlines of geomorphic types. Based on the investigative data, the exogenic forces and marine organism conditions concerning tropical coast development in the area are expounded, and coastal dynamo-deposition geomorphic bodies are analysed, mainly with sea cliff-abrasion platform,barrier-lagoon system, modern beach, coral reef and mangrove tidal flat, and the general process of coastal evolution at this area, as well as coastline changes since middle Holocene transgression.
文摘<strong>Introduction:</strong> Modern family planning methods (MFPM) prevent unwanted pregnancies, reduce fertility rate, and increase the interval between pregnancies. They prevent pregnancy by preventing fertilization or implantation of the fertilized ovum. MFPM include tubal ligation (TL), vasectomy, oral contraceptive pills, the intrauterine contraceptive device (IUCD), depot injections, sub-dermal implants, and male and female condoms. <strong>Objective: </strong>To determine the level of knowledge of modern family planning methods (MFPM) among women of reproductive age (18 - 49 years) at the Mathari North Health Center in Nairobi County, Kenya. <strong>Methods: </strong>The study conducted among women of reproductive age at Mathare North Health Center in Nairobi was a cross-sectional descriptive survey between March 2016 and November 2018. It provided both qualitative and quantitative data. The sample size comprised of 274 women of reproductive age,<em> i.e.</em> (18 - 49 years) attending antenatal and postnatal clinics at the facility. Those excluded were women below 18 years of age, as they could not give consent according to Kenyan Laws. The data were collected using an interviewer-administered structured questionnaire, which consisted of socio-demographic and characteristics, knowledge of modern family planning methods and distance from the facility. Likert scale was used to ensure that data was tabulated on daily basis and subjected to statistical manipulation using Statistical Package for Social Sciences (SPSS). <strong>Results:</strong> The four leading MFPM in use in order of acceptability were injectables, implants, intrauterine contraceptive device and pills in that order. 91% of respondents were aware or had heard about modern family planning methods. Level of education of mother and father were the two variables that influenced the uptake of MFPM with <em>p</em>-values of 0.0260 and 0.025, respectively. The study further found that knowledge of MFPM had a significant influence on their assimilation and utilization. All secondary variables considered in the research exhibit a substantial relationship concerning the use of MFPM. <strong>Conclusion:</strong> Communities around Mathari North Health Center need to be given information;education and counselling on MFPM to enable them make an informed decision and choice on their preferred method of family planning.
文摘Objective: To examine and measure the decision-making processes involved in Visual Recognition of Facial Emotional Expressions (VRFEE) and to study the effects of demographic factors on this process. Method: We evaluated a newly designed software application (M.A.R.I.E.) that permits computerized metric measurement of VRFEE. We administered it to 204 cognitively normal participants ranging in age from 20 to 70 years. Results: We established normative values for the recognition of anger, disgust, joy, fear, surprise and sadness expressed on the faces of three individuals. There was a significant difference in the: 1) measurement (F (8.189) = 3896, p = 0.0001);2) education level (x2(12) = 28.4, p = 0.005);3) face (F(2.195) = 10, p = 0.0001);4)series (F (8.189)=28, p = 0.0001);5) interaction between the identity and recognition of emotions (F (16, 181 =11, p = 0.0001). However, performance did not differ according to: 1) age (F (6.19669) = 1.35, p = 0.2) or 2) level of education (F (1, 1587) = 0.6, p = 0.4). Conclusions: In healthy participants, the VRFEE remains stable throughout the lifespan when cognitive functions remain optimal. Disgust, sadness, fear, and joy seem to be the four most easily recognized facial emotions, while anger and surprise are not easily recognized. Visual recognition of disgust and fear is independent of aging. The characteristics of a face have a significant influence on the ease with which people recognize expressed emotions (idiosyncrasy). Perception and recognition of emotions is categorical, even when the facial images are integrated in a spectrum of morphs reflecting two different emotions on either side.
文摘This paper begins with the overthrow of the concept of combining ability in crossbreeding by the concept of heritability.The reason is that general combining ability changes with the number and kind of pure strains in the foundation stock and hence special combining ability changes also,so that work with different kinds of pure strains in the foundation stock cannot be compared.Hence combining ability is useless as a parameter to predict the amount of heterosis expected in the next generation.On the other hand,since each cross has a separate heritability,it can be applied to a cross population just as successfully as in purebreeding.Since the same concept holds in both cases,resort to any other concept would be superfluous.That's why combining ability must be rejected.Another reason(not given in the full text)is,an infinite number of pure strains would be required in the foundation stock for its results to be comparable with those of the heritability theory,which disposes of its utility altogether.The main content of the thesis is then the centennial enigma of heterosis can be resolved by Descarte's theoretic method of deduction.Accordingly we start from the definition of heterosis.H=F¡-MP,where H is heterosis,F,is the first generation offspring,MP is the mean of the parents or midparent,and from the use of a binomial random variable and its extention to the multinomial case derive the basic relations of heterosis with its components.Starting with second degree statistics,we obtain Vn=Vr,-2cov(F,,MP)+Vup,where V and cov stand for variance and covariance.The equations of heterosis are v„=(1/2)Na²+(1/4)Nd’+Vr(F,)=additive dominance F,epistasis Vup=(1/2)Na’+(1/2)V1,additive parental epistasis V„=(1/4)Nd’+V(F)+(1/2)V1,dominance F,epistasis parental epistasis.where N is number of genes controlling a trait,a=(P1-P,)12,d is deviation from midparent,while the variance components are all indicated by their names under the repective terms.It turns out that all these can be easily computed from the data so that the problem becomes a simple one which any college student may solve.In other words,the right answers are found when the right questions are asked.Who had ever shown that the heritability principle is inapplicable in crossbreeding,e.g.,in a crossing of two pure strains?From this cue arose the realization that the F,of a cross of two pure strains must also be a Mendelian population,with p and q both equal to 1/2 which simplifies the algebra outright.This Heritability Theory of Heterosis,or HTH in capital letters,re-sts on 2 initial anguments:1)Since 0.5+0.5=1,crossing two pure strains gives a population which is only a special case of pure-breeding,thereforea heritability coefficient must exist for the F1;2)Our problem reduces to that of finding that coefficient;the an-swer is given by the additive component divided by Ve.,i.e.,(1/2)No'1 Vp..which is readily found from the solution of the het-erosis equations.Thus the elemnal enigma of heterosis is resolved!This happened at the end of the 20th century.We now come to the second point of the discovery,the new genetic parameter crossheritability which will rise in size with the increase of the number of times it's used and form the link between breeding and evolution.The advent of the Age of Evolution Engineering in the 21st century marks a totally new era,showing that artificial will ultimately supercede natural selection,with the long span of time element eliminated.For agriculture at least,it means there is no limit to the increase of food supply by the new method,with the concentra-tion of desirable genes by hybridization in place of the old theory of their fixation.Genetic gain is achieved through artificial selec-tion,with an 80%saving of time,labor and cost by adoption of the new method.Applied to a further increase in all kinds of agri-cultural products including hybrd rice,it means that a huge eacalation,in fact a New Green Revolution,on a much langer scale than that of any such before,is in view,provided it is adopted in our research and educational institutions as early as possible,ere its spread elsewhere.The possibilities from the evolution point of view can only be pictured by science fiction.
文摘The underpinning problems of deep-water facies still remain unresolved.(1) The Tb, Tc, and Td divisions of the turbidite facies model, with traction structures, are an integral part of the "Bouma Sequence"(Ta, Tb, Tc, Td, Te).However, deposits of thermohaline contour currents, wind-driven bottom currents, deep-marine tidal currents, and baroclinic currents(internal waves and tides) also develop discrete rippled units, mimicking Tc.(2) The application of "cut-out" logic of sequences, which was originally introduced for the "Bouma Sequence", with sharp basal contacts and sandy divisions containing well-developed traction structures, to muddy contorts with gradational basal contacts and an absence of well-developed traction structures is incongruent.(3) The presence of five internal divisions and hiatus in the muddy contoured facies model is in dispute.(4) Intersection of along slope contour currents with down slope sediment-gravity flows, triggering hybrid flows, also develops traction structures.(5) The comparison of genuine hybrid flows with down slope flow transformation of gravity flows is inconsistent with etymology of the term "hybrid".(6) A reexamination of the Annot Sandstone at the Peira Cava type locality in SE France fails to validate either the orthodoxy of five internal divisions of the "Bouma Sequence" or their origin by turbidity currents. For example, the "Ta" division is composed of amalgamated units with inverse grading and floating mudstone clasts, suggesting a mass-transport deposit(MTD). The "Tb" and "Tc" divisions are composed of double mud layers and sigmoidal cross bedding, respectively, which suggest a tidalite origin.(7) Although it was reasonable to introduce a simplistic "Bouma Sequence" in 1962, at a time of limited knowledge on deep-water processes, it is obsolete now in 2021 to apply this model to the rock record amid a wealth of new knowledge.(8)The disconnect between 12 observed, but questionable, modern turbidity currents and over 10,000 interpreted ancient turbidites defies the doctrine of uniformitarianism. This disconnect is attributed to routine application of genetic facies models, without a pragmatic interpretation of empirical data.(9) A suggested solution to these problems is to interpret traction structures in the sedimentary record pragmatically on the basis of empirical field and experimental evidence, without any built-in bias using facies models, such as the "Bouma Sequence".(10) Until reliable criteria are developed to distinguish traction structures of each type of bottom currents based on uniformitarianism, a general term "BCRS"(i.e., bottom-current reworked sands) is appropriate for deposits of all four kinds of bottom currents.
基金the National Natural Science Foundation of China (60743007)Fujian Province Young Talent Program (2006F3044)+2 种基金Province Natural Science Foundation of Fujian (JA04169)Province Education Department Foundation of Fujian (JB05331)Beijing Municipal Commission of Education Disciplines and Graduate Education Projects (XK100130648)
文摘The typeⅡ codes have been studied widely in applications since their appearance. With analysis of the algebraic structure of finite field of order 4 （i.e., GF（4））, some necessary and sufficient conditions that a generalized H-code （i.e., GH-code） is a type Ⅱ code over GF（4） are given in this article, and an efficient and simple method to generate type Ⅱ codes from GH-codes over GF（4） is shown. The conclusions further extend the coding theory of type Ⅱ.
文摘The pristine point of zero charge(p.p.z.c)and zeta potential as a function of pH of boehmite oxide/hydroxide(α-Al_(2)O_(3)·H_(2)O)have been determined for three filter media.The active component in the first two filter media is boehmite nanofibers,only 2 nm in diameter and about 300 nm long.Boehmite nanofibers create high zeta potential(ζtrue≥46 mV)in aqueous solutions in the pH range of 3–8.The p.p.z.c.values were determined to be 11.60±0.15 for nanofibers grafted onto microglass fibers and 11.40±0.15 for agglomerated nanofibers.In the third filter media,a boehmite nanolayer in the form of monocrystalline oxide/hydroxide with a thickness of approximately 1.2 nm is electroadhesively deposited onto siliceous support material with large surface area of about 50 m^(2)/g,therefore forming a highly electropositive composite of boehmite nanolayer on the second highly electronegative solid.Boehmite’s oxide-hydroxide nanolayer surface creates high zeta potential(ζtrue≥50 mV)in aqueous solutions in the pH range of 3–8.The p.p.z.c.value was determined to be 11.38±0.15.The reported values are within accuracy,but they are much higher than the values reported in the literature.X-ray powder diffraction data were supplemented by microscopy,infrared spectroscopy in order to characterize fully synthetic boehmite surfaces.
